i think its different for everyone, personally i never experience high high and low lows. im a sagitarious so my sign says i have a pretty happy go lucky attitude and seek adventure and all that. i move about every 4 years sanfrancisco , LA,NY etc.
i have good friends in those places and they definitely allow me to be happy, as i can express myself and they "get" me. so i know its a bummer if you feel like people left you.
again though i think its different for everyone, i only recently opened up to the idea of reincarnation and spirituality on the whole. its made me more at peace and far less judgemental of people and more accepting of the yin and the yang, good and bad- which has led to less frustration.
i would say if they left you, you should look inward and learn to rely on your inner strength which we all have loads of. i dont know what you need to achieve this but i would say maybe they left if they felt you relied on them too much and were not growing.
in the same way "god helps those who help themselves" is the same reason why ET's wont "save" us, WE need to save us. we grow from having to deal with our own problems and not relying on others.
thats not to say they cant help, but when help becomes a crutch its not really help anymore.
hope thats not too cold of an analysis!