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Tesla_WTC_Solution
22nd September 2013, 01:09
Hello Avalon,
I wanted to make a safe place where anyone who wants to share an autism research link can post that, and of course, discuss the papers posted.

Since there are so many possible underlying factors being investigated, threads about autism often get derailed as people talk about more familiar assumptions and theories, and of course, the vaccination debate tends to darken some of those discussions for people who are unfamiliar with the more recent body of research in regards to de novo mutations and lack of evidence regarding whether autism is heritable.

There was a paper in particular that I want you guys to read if and when you have time. The reason I want to talk about this here is that I trust most of you not only to leave this material safely here, but also to engage and to care about this issue, as people with autism and mental retardation often suffer a lot of discrimination when their families seek benefits from the state or federal gov'ts.

The paper my spouse and I found is called:


Somatic Mutation, Genomic Variation,
and Neurological Disease
Annapurna Poduri, Gilad D. Evrony, Xuyu Cai, Christopher A. Walsh*

http://www.walshlab.org/uploads/publications/244/2013sciencesomaticmutationreviewpoduri.pdf

Background: Genetic mutations that cause human disease are conventionally considered to be inherited from one’s parents and present in all somatic (body) cells. We do know, however, that most mutations that cause cancer arise somatically, and we are becoming increasingly aware of mutations that cause otherdiseases and that arise de novo, meaning they are undetectable inthe parents. Some such de novo mutations arise in the gamete of a parent, but some arise after fertilization during embryonic development,generating somatic mutations. Somatic mutations occur in several neurodevelopmental diseases associated with epilepsy, autism spectrum disorders, and intellectual disability, although their broader relevance for neurological disease is unknown.

Advances: A key recent advance has been the increasing identification of somatic mutations in affected tissues. For example, somatic mutations in several genes (PIK3CA, AKT3, and mTOR) cause enlargement of just one hemisphere of the brain, a malformation called hemimegalencephaly that is highly associated with epilepsy.




A similar
phenomenon occurs in the multisystem disorder
tuberous sclerosis complex (TSC), a condition
caused by mutations in the genes TSC1 and TSC2
(33, 34), whose gene products form a protein complex together and regulate the mammalian target of rapamycin (mTOR) pathway;

I am not going to post the whole document here and I respectfully ask that people try to copy/paste the specific parts of documents being referenced in conversation, in an effort to keep the total wordcount of the thread to a usable minimum while we talk about what's in the papers and how it affects our beliefs regarding the causation of autism.

In regards to what I posted above from the document, I wanted to say, on my website Nuclearnuttery.com, I predicted about two years ago that autism and the mTOR pathway had something to do with each other. I had been reading about experimental vaccines and vaccine adjuvants that affect the mTOR pathway while allegedly having something to do with the AIDS cure. I wrote an article covering lots of different things, but when I found that bit about mTOR pathway, something inside told me it was a thing I needed to follow up on. And here it is, published in July 2013 LOL!

I am actually quite hurt that my own research was taken offline. The autism articles on my website were getting 100s of reads per week at the end of the life of the blog.

Please contribute any number of links you wish, hopefully most of them from the last few years if you don't mind, here for us to see and think about. I know for a fact that there are people out there who DO care and WANT to find a cure. It doesn't matter if eugenicists like J Craig Venter or Bill Gates would rather keep on reducing the numbers of useful people in the world. We are people too and we care more, so we are going to win against the corporations.

I am looking forward to visiting this thread frequently and hope that anyone/everyone finds a link that will surprise me and give me food for thought. Most people don't have the knowledge to discuss these ideas, including me, but education is a process and we are all capable of learning more.

Tesla_WTC_Solution
22nd September 2013, 16:23
the message i entered was too short as it was 100% quoted, lol


http://law-roundtable.uchicago.edu/s05.html
THE UNIVERSITY OF CHICAGO LAW SCHOOL
R O U N D T A B L E
1 1 1 1 E A S T 6 0 T H S T R E E T
C H I C A G O I L L I N O I S 6 0 6 3 7
Return to Home Page
1996 Symposium Abstracts

Genetics and the Law: The Ethical, Legal, and Social Implications of Genetic Technology and Biomedical Ethics



http://www.igs.cnrs-mrs.fr/SERV/supplementalData/Legendre_SupplementalTableS3full.php

Genelists


http://www.walshlab.org/uploads/publications/244/2013sciencesomaticmutationreviewpoduri.pdf

Somatic Mutation, Genomic Variation,
and Neurological Disease
Annapurna Poduri, Gilad D. Evrony, Xuyu Cai, Christopher A. Walsh*


http://www.tcdb.org/search/index.php?query=&type=system

The voltage-dependent L-type Ca2+ channel α-subunit-1C (L-type Cav1.2), CACNA1C (mutations cause Timothy's syndrome, a disorder associated with autism) (Splawski et al., 2006). The C-terminus of Cav1.2 encodes a transcription factor (Gomez-Ospina et al., 2006). Cav1.2 associates with the α-2, δ-1, β and γ subunits (Yang et al., 2011). The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channel, Cav1.2 (Park et al., 2010). This channel appears to function as the molecular switch for synaptic transmission (Atlas 2013). Intramembrane signalling occurs with syntaxin 1A for catecholamine release in chromaffin cells (Bachnoff et al. 2013).

Animals

CACNA1C of Homo sapiens (2221 aas; Q13936)

The voltage-dependent L-type Ca2 channel α-subunit-1H (T-type Cav3.2), CACNA1H (mutations can cause an increased propensity for autism spectrum disorders (ASD) characterized by impaired social interactions, communication skills and restricted and repetitive behaviors) (Splawski et al., 2006). Also called Cav3.2 or VSCC. Involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1H gives rise to T-type calcium currents, ''low-voltage activated'' currents blocked by nickel and mibefradil. Defective in Childhood Absence Epilepsy. Are permeated by divalent metal ions, such as Fe2 and Mn2 , and possibly Cd2 (Thévenod, 2010). Patented inhibitors of T-type calcium channels have been reviewed (Giordanetto et al. 2011).

Animals

CACNA1H of Homo sapiens (2353 aas; Q95180)


http://www.frontiersin.org/Cellular_Neuroscience/10.3389/fncel.2013.00028/full

| doi: 10.3389/fncel.2013.00028
Reversing autism by targeting downstream mTOR signaling
Hansen Wang1* and Laurie C. Doering2*
1Faculty of Medicine, University of Toronto, Toronto, ON, Canada
2Department of Pathology and Molecular Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada
A commentary on
Autism-related deficits via dysregulated eIF4E-dependent translational control
by Gkogkas, C. G., Khoutorsky, A., Ran, I., Rampakakis, E., Nevarko, T., Weatherill, D. B., et al. (2013). Nature 493, 371–377.



http://onlinelibrary.wiley.com/doi/10.1002/ajmg.b.30761/abstract;jsessionid=9667C0C88CFB401A74D413DBF781FD23.d02t02?systemMessage=Wiley+Online+Library+will+ be+unavailable+for+approximately+4+hours+between+09%3A00+EDT+and+14%3A00+EDT+on+Saturday%2C+28+Septe mber+2013+as+we+make+upgrades+to+improve+our+services+to+you.+There+will+also+be+some+delays+to+onli ne+publishing+between+25+to+28+September+2013.+We+apologize+for+the+inconvenience+and+appreciate+you r+patience.+Thank+you+for+using+Wiley+Online+Library%21&userIsAuthenticated=false&deniedAccessCustomisedMessage=

PRNP mutations in a series of apparently sporadic neurodegenerative dementias in China†

Liu Zheng1,2, Jia Longfei1,2, Ye Jing1,2, Zhang Xinqing1,2, Song Haiqing1,2, Lv Haiyan1,2, Wang Fen1,2, Dong Xiumin1,2, Jia Jianping1,2,*
Article first published online: 18 APR 2008

DOI: 10.1002/ajmg.b.30761

Copyright © 2008 Wiley-Liss, Inc.


http://www.autismspeaks.org/science/grants/pi3kmtor-signaling-novel-biomarker-and-therapeutic-target-autism
Science » Grant Search » Results » PI3K/mTOR signaling as a novel biomarker and therapeutic target in autism
Search
PI3K/mTOR signaling as a novel biomarker and therapeutic target in autism

Status: Completed

Investigator: Bassell, Gary

Institution: Emory University

Grant Amount: $100,000.00



https://sfari.org/funding/grants/abstracts/role-of-tsc-mtor-signaling-pathway-in-autism-and-autism-spectrum-disorders


Home > Funding > Grant opportunities > Abstracts > Role of TSC/mTOR signaling pathway in autism and autism spectrum disorders
Role of TSC/mTOR signaling pathway in autism and autism spectrum disorders
Vijaya Ramesh, Ph.D.
Massachusetts General Hospital


For years, autism has been noted in individuals with tuberous sclerosis, leading researchers to speculate that the two disorders may develop after troubles in the same biological pathway. Vijaya Ramesh and her colleagues at Massachusetts General Hospital are pursuing this lead by investigating whether genes linked to tuberous sclerosis are also associated with autism spectrum disorders.

The TOR pathway, which is named after a key protein that receives information on the cell surface, controls the growth of many cells and regulates the connections neurons make with each other. Mutations that remove regulators of the TOR pathway are associated with tuberous sclerosis. Ramesh hypothesizes that disruptions in this pathway may also cause the neuronal abnormalities that lead to autism.

Ramesh and her colleagues are examining the genes of several components of the TOR pathway, looking for rare variations that are associated with autism. By narrowing their focus, the researchers will be able to analyze more samples drawn from the Simons Simplex Collection, with a greater attention to detail in the candidate genes. Once one mutation is linked to autism, the researchers can try to find the mutation among more people with autism to make the correlation stronger. The team will also perform assays in cultured neurons to see how the mutations affect TOR pathway activity.

The investigators have adopted a two-tier pooling strategy wherein 10 DNA pools each of 300 patients (30 samples per pool) and 600 control samples (60 samples per pool) have been assembled. After completing sequencing of the 300 patient samples and 600 controls, the researchers plan to identify rare variations that are specific to autism samples. In future studies, they aim to confirm the identified variants in additional samples and validate these variants in functional assays using cultured neurons. This work will potentially identify novel pathways and strategies for autism treatment.

Tesla_WTC_Solution
22nd September 2013, 16:27
And more on mTOR

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075964/

Rapamycin for treating Tuberous Sclerosis and Autism Spectrum Disorders
Dan Ehninger and Alcino J. Silva

Additional article information

Abstract
Tuberous sclerosis (TSC) is a genetic disorder caused by heterozygous mutations in the TSC1 or TSC2 genes and is associated with autism spectrum disorders (ASD) in 20–60% of cases. In addition, altered TSC/mTOR signaling is emerging as a feature common to a subset of ASD. Recent findings, in animal models, show that restoration of the underlying molecular defect can improve neurological dysfunction in several of these models, even if treatment is initiated in adult animals, suggesting that pathophysiological processes in the mature brain contribute significantly to the overall neurological phenotype in these models. These findings suggest that windows for therapeutic intervention in ASD may be wider than thought previously.

Keywords: Tuberous sclerosis, TSC, mTOR, autism, ASD, rapamycin, pharmacology, treatment





http://medicalxpress.com/news/2013-06-role-mtor-autism-related-disorders.html
HomeNeuroscienceJune 3, 2013
Researchers have found new role for mTOR in autism-related disorders
by Shraddha Chakradhar

(Medical Xpress)—Researchers have found a novel role for a protein that has been implicated in an autism-related disorder known as tuberous sclerosis complex (TSC).
The disease, which affects 1 in about 8,000 children, manifests itself in the form of mental retardation in addition to severe epileptic episodes. The disease is caused by mutations in two tumor-suppressing proteins, TSC1 and TSC2.
"Kids with this condition have benign tumors that grow all over the body," said Bernardo Sabatini, the Takeda Professor of Neurobiology at Harvard Medical School and senior author of the study, "but we wanted to know what happened in the brain."
The researchers found that when mutations in TSC1 and TSC2 adversely affected a third protein, mTOR, this mutation increased brain activity, which can result in epileptic seizures.

The findings were published in the May 8 issue of Neuron.
A protein kinase, mTOR is responsible for controlling cell growth in many parts of the body and has been widely implicated in epilepsy and autism. TSC1 and TSC2 normally repress the activity of mTOR to keep cell growth in check. In the case of TSC, there are mutations in TSC1 or TSC2, and mTOR's ability to promote cell growth goes unchecked, resulting in tumors in regularly dividing cells.

"But neurons don't divide," said Sabatini. "So it was important to note the changes in these non-dividing cells."
The researchers hypothesized that mTOR's function in the brain related to homeostasis, the brain's ability to maintain a controlled level of electrical activity. When there's a lot of electrical activity, a negative feedback system switches on to suppress activity. Conversely, when levels are too low, other positive feedback pathways are engaged that bring the activity level back up.

Tesla_WTC_Solution
22nd September 2013, 16:37
infantile spasms


http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075964/

Epilepsy is also an important and common clinical feature of TSC and affects approximately 70–80% of subjects over their lifetime [90, 93]. Infantile spasms, a form of early childhood epilepsy, are diagnosed in approximately 50% of individuals with TSC [90, 93] and constitute a risk factor for ASD. Psychiatric disorders, including depression and anxiety, are also frequently encountered in TSC populations [13, 94].



http://community.babycenter.com/post/a27237503/vaccines_and_infantile_spasms

Vaccines and Infantile Spasms

Bookmark it

SunkistSweete
Posted 04/12/2011
I posted this on the non-vaxing board too but I wanted to get a lot of opinions so Im posting here as well.

My friend just called me and told me that her son was diagnosed with infantile spasms.� He just received his 6 month shots last week and started showing symtoms on Saturday.� She took him to the ped yesterday after he had a severe spasm and his eyes rolled back into his head and they sent her to the hosptial.� From what I have been able to research there is a link between the DTaP shot and infantile spasms, but of course doctors will deny this.� I had talked to her about vaccine dangers before he was born and she did not want to vaccinate, but her husband was totally opposed to that.� She has decided to discontinue vaccines and now that this has happened he agreed.� Does anyone have any information or evidence on the link between vaccines and infantile spasms or has anyone encountered this before with a vaxed child?

--
TTC #1 since 9/10 M/C 3/11/11 at 6 weeks 2 days:(

penn
23rd September 2013, 01:51
Thought you might be interested in Keri Riverra's success with autism. Search on her name or mms and autism. Some awesome testimonials. I'd put you some links but they probably wouldn't go anywhere. :)

A total of 100 children have been recovered (ATEC score of 10 or below,) using the CD Autism parasite protocol published in Kerri Rivera´s new book Healing the Symptoms Known as Autism.

CD = Chlorine Dioxide, the active ingredient of MMS1.

Tesla_WTC_Solution
23rd September 2013, 07:41
http://www.autismspeaks.org/news/news-item/clinical-trial-tests-possible-treatment-autism
http://www.autismspeaks.org/science/science-news/autism-risk-gene-linked-sensory-overload

However, these effects could be blocked by treating the PTEN-deficient mice with rapamycin, a powerful immune-system suppressant most commonly prescribed to prevent organ rejection. In examining the animal’s brain tissues, the researchers found that the drug prevented the abnormal increase in cell interconnections otherwise seen in PTEN-deficient mice (image above).

“While this study is exciting, we need to know more before it would be appropriate to use rapamycin as a treatment for individuals with autism,” adds Joe Horrigan, M.D., Autism Speaks head of medical research. “Safety considerations are of paramount importance as rapamycin can increase susceptibility to infections and malignancies such as lymphoma. At present, it should be prescribed only by physicians experienced in immunosuppressive therapy.”


http://clinicaltrials.gov/ct2/show/NCT01929642

Rapamycin for Autism Phenotype in TSC: A Feasibility Study (RAPT)
This study is currently recruiting participants.
Verified August 2013 by Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Sponsor:
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Information provided by (Responsible Party):
Tanjala Gipson, Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
ClinicalTrials.gov Identifier:
NCT01929642
First received: August 7, 2013
Last updated: August 28, 2013
Last verified: August 2013
History of Changes
Full Text View Tabular ViewNo Study Results PostedDisclaimerHow to Read a Study Record
Purpose
The purpose of this study is to assess the feasibility and safety of administering sirolimus in participants with Tuberous Sclerosis Complex (TSC) and self-injury and to measure cognitive and behavioral changes, including reduction in autistic symptoms, self-injurious and aggressive behaviors, as well as improvements in cognition across multiple domains of cognitive function.

http://www.ncbi.nlm.nih.gov/pubmed/23250422

Nat Commun. 2012;3:1292. doi: 10.1038/ncomms2295.
Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex.
Sato A, Kasai S, Kobayashi T, Takamatsu Y, Hino O, Ikeda K, Mizuguchi M.
Source
Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156 8506, Japan.
Abstract
Impairment of reciprocal social interaction is a core symptom of autism spectrum disorder. Genetic disorders frequently accompany autism spectrum disorder, such as tuberous sclerosis complex caused by haploinsufficiency of the TSC1 and TSC2 genes. Accumulating evidence implicates a relationship between autism spectrum disorder and signal transduction that involves tuberous sclerosis complex 1, tuberous sclerosis complex 2 and mammalian target of rapamycin. Here we show behavioural abnormalities relevant to autism spectrum disorder and their recovery by the mammalian target of rapamycin inhibitor rapamycin in mouse models of tuberous sclerosis complex. In Tsc2(+/-) mice, we find enhanced transcription of multiple genes involved in mammalian target of rapamycin signalling, which is dependent on activated mammalian target of rapamycin signalling with a minimal influence of Akt. The findings indicate a crucial role of mammalian target of rapamycin signalling in deficient social behaviour in mouse models of tuberous sclerosis complex, supporting the notion that mammalian target of rapamycin inhibitors may be useful for the pharmacological treatment of autism spectrum disorder associated with tuberous sclerosis complex and other conditions that result from dysregulated mammalian target of rapamycin signalling.
PMID: 23250422 [PubMed - indexed for MEDLINE] PMCID: PMC3535343 Free PMC Article

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607786/

Reversing autism by targeting downstream mTOR signaling
Hansen Wang and Laurie C. Doering

Additional article information

Autism spectrum disorders (ASDs) are a group of clinically and genetically heterogeneous neurodevelopmental disorders characterized by impaired social interactions, repetitive behaviors and restricted interests (Baird et al., 2006; Zoghbi and Bear, 2012). The genetic defects in ASDs may interfere with synaptic protein synthesis. Synaptic dysfunction caused by aberrant protein synthesis is a key pathogenic mechanism for ASDs (Kelleher and Bear, 2008; Richter and Klann, 2009; Ebert and Greenberg, 2013). Understanding the details about aberrant synaptic protein synthesis is important to formulate potential treatment for ASDs. The mammalian target of the rapamycin (mTOR) pathway plays central roles in synaptic protein synthesis (Hay and Sonenberg, 2004; Hoeffer and Klann, 2010; Hershey et al., 2012). Recently, Gkogkas and colleagues published exciting data on the role of downstream mTOR pathway in autism (Gkogkas et al., 2013) (Figure ​(Figure11).


Previous studies have indicated that upstream mTOR signaling is linked to ASDs. Mutations in tuberous sclerosis complex (TSC) 1/TSC2, neurofibromatosis 1 (NF1), and Phosphatase and tensin homolog (PTEN) lead to syndromic ASD with tuberous sclerosis, neurofibromatosis, or macrocephaly, respectively (Kelleher and Bear, 2008; Bourgeron, 2009; Hoeffer and Klann, 2010; Sawicka and Zukin, 2012). TSC1/TSC2, NF1, and PTEN act as negative regulators of mTOR complex 1 (mTORC1), which is activated by phosphoinositide-3 kinase (PI3K) pathway (Kelleher and Bear, 2008; Auerbach et al., 2011; Sawicka and Zukin, 2012) (Figure ​(Figure1).1). Activation of cap-dependent translation is a principal downstream mechanism of mTORC1. The eIF4E recognizes the 5′ mRNA cap, recruits eIF4G and the small ribosomal subunit (Richter and Sonenberg, 2005; Hershey et al., 2012). The eIF4E-binding proteins (4E-BPs) bind to eIF4E and inhibit translation initiation.

http://questioning-answers.blogspot.com/2012/06/mtor-and-autism.html

http://questioning-answers.blogspot.com/2012/06/mtor-and-autism.html

http://asdresearchinitiative.wordpress.com/2013/03/02/autism-epilepsy-tuberous-sclerosis-and-the-mtor-pathway/

Autism , Epilepsy, Tuberous Sclerosis and the mTOR pathway
Posted on March 2, 2013 by researchinitiative
Autism, epilepsy and tuberous sclerosis complex: a functional model linked to mTOR pathway.

http://www.ncbi.nlm.nih.gov/pubmed/23446718

Hospital Infantil Universitario Nino Jesus, 28009 Madrid, Espana.

Abstract

INTRODUCTION.

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that results from mutations in the TSC1 or TSC2 genes and is associated with hamartoma formation in multiple organ systems. Brain disorders are the origin of more frequent and severe problems and include infantile spasms, intractable epilepsy, brain tumors, cognitive disabilities, and autism. TSC1 or TSC2 encoded proteins modulate cell function via the mTOR signaling cascade and serve as keystones in regulating cell growth and proliferation.

AIM.

To review the etiopathogenic mechanisms and the natural course of the association of autism and epilepsy in TSC.

DEVELOPMENT.

Both the clinical and the neuroimaging findings of TSC, including early onset epilepsy and the localization of cortical tubers in the temporal lobes, and the molecular understanding of the mTOR signaling pathway, not only involved in cell growth, but also in synaptogenesis, synaptic plasticity and neuronal functioning, have suggested a multimodal origin of autism in these patients.

CONCLUSIONS. A greater understanding of the pathogenetic mechanisms underlying autism in TSC could help in devising targeted and potentially more effective treatment strategies. Antagonism of the mTOR pathway with rapamycin and everolimus may provide new therapeutic options for these TSC patients.

——————-

Neural connectivity abnormalities in autism: Insights from the tuberous sclerosis model.

http://www.ncbi.nlm.nih.gov/pubmed/23445933

Autism Spectrum Disorder (ASD) is a behavioral syndrome caused by complex genetic and non-genetic risk factors. It has been proposed that these risk factors lead to alterations in the development and ‘wiring’ of brain circuits and hence, the emergence of ASD.

Although several lines of research lend support to this theory, etiological and clinical heterogeneity, methodological issues and inconsistent findings have led to significant doubts. One of the best established, albeit rare, causes of ASD is the genetic condition Tuberous Sclerosis Complex (TSC), where 40% of individuals develop ASD.

A recent study by Peters and Taquet et al. analyzed electroencephalography (EEG) data using graph theory to model neural ‘connectivity’ in individuals with TSC with and without ASD and cases with ‘idiopathic’ ASD. TSC cases exhibited global under-connectivity and abnormal network topology, whereas individuals with TSC + ASD demonstrated similar connectivity patterns to those seen in individuals with idiopathic ASD: decreased long- over short-range connectivity.

The similarity in connectivity abnormalities in TSC + ASD and ASD suggest a common final pathway and provide further support for ‘mis-wired’ neural circuitry in ASD. The origins of the connectivity changes, and their role in mediating between the neural and the cognitive / behavioral manifestations, will require further study. Please see related research article here http://www.biomedcentral.com/1741-7015/11/54.

———————–

Brain functional networks in syndromic and non-syndromic autism: a graph theoretical study of EEG connectivity.

http://www.ncbi.nlm.nih.gov/pubmed/23445896
BACKGROUND:

Graph theory has been recently introduced to characterize complex brain networks, making it highly suitable to investigate altered connectivity in neurologic disorders.

A current model proposes autism spectrum disorder (ASD) as a developmental disconnection syndrome, supported by converging evidence in both non-syndromic and syndromic ASD. However, the effects of abnormal connectivity on network properties have not been well studied, particularly in syndromic ASD. To close this gap, brain functional networks of electroencephalographic (EEG) connectivity were studied through graph measures in patients with Tuberous Sclerosis Complex (TSC), a disorder with a high prevalence of ASD, as well as in patients with non-syndromic ASD.

Tesla_WTC_Solution
23rd September 2013, 07:44
SV40 MAY BE CAUSING MTOR CHANGES IN AUTISM

http://jvi.asm.org/content/79/11/6882


Effects of Simian Virus 40 Large and Small Tumor Antigens on Mammalian Target of Rapamycin Signaling: Small Tumor Antigen Mediates Hypophosphorylation of eIF4E-Binding Protein 1 Late in Infection
Yongjun Yu, Sagar B. Kudchodkar, and James C. Alwine*
+ Author Affiliations

Department of Cancer Biology, Abramson Family Cancer Research Institute, University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania 19104-6142
ABSTRACT

We report that late in a simian virus 40 (SV40) infection in CV-1 cells, there are significant decreases in phosphorylations of two mammalian target of rapamycin (mTOR) signaling effectors, the eIF4E-binding protein (4E-BP1) and p70 S6 kinase (p70S6K). The hypophosphorylation of 4E-BP1 results in 4E-BP1 binding to eIF4E, leading to the inhibition of cap-dependent translation. The dephosphorylation of 4E-BP1 is specifically mediated by SV40 small t antigen and requires the protein phosphatase 2A binding domain but not an active DnaJ domain. Serum-starved primary African green monkey kidney (AGMK) cells also showed decreased phosphorylations of mTOR, 4E-BP1, and p70S6K at late times in infection (48 h postinfection [hpi]). However, at earlier times (12 and 24 hpi), in AGMK cells, phosphorylated p70S6K was moderately increased, correlating with a significant increase in phosphorylation of the p70S6K substrate, ribosomal protein S6. Hyperphosphorylation of 4E-BP1 at early times could not be determined, since hyperphosphorylated 4E-BP1 was present in mock-infected AGMK cells. Elevated levels of phosphorylated eIF4G, a third mTOR effector, were detected in both CV-1 and AGMK cells at all times after infection, indicating that eIF4G phosphorylation was induced throughout the infection and unaffected by small t antigen. The data suggest that during SV40 lytic infection in monkey cells, the phosphorylations of p70S6K, S6, and eIF4G are increased early in the infection (12 and 24 hpi), but late in the infection (48 hpi), the phosphorylations of mTOR, p70S6K, and 4E-BP1 are dramatically decreased by a mechanism mediated, at least in part, by small t antigen.

FOOTNOTES

Received 22 December 2004.
Accepted 7 February 2005.
↵*Corresponding author. Mailing address: 314 Biomedical Research Building, 421 Curie Blvd., University of Pennsylvania, Philadelphia, PA 19104-6142. Phone: (215) 898-3256. Fax: (215) 573-3888. E-mail: alwine@mail.med.upenn.edu.


http://en.wikipedia.org/wiki/SV40


SV40 is an abbreviation for Simian vacuolating virus 40 or Simian virus 40, a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses, SV40 is a DNA virus that has the potential to cause tumors, but most often persists as a latent infection.

SV40 became a highly controversial subject after it was revealed that millions were exposed to the virus after receiving a contaminated polio vaccine produced between 1955 and 1961.[1]

http://www.ncbi.nlm.nih.gov/pubmed/20345322


J Neurovirol. 2010 Mar;16(2):141-9. doi: 10.3109/13550281003685839.
Association of autism with polyomavirus infection in postmortem brains.
Lintas C, Altieri L, Lombardi F, Sacco R, Persico AM.
Source
Laboratory of Molecular Psychiatry and Neurogenetics, University Campus Bio-Medico, Rome, Italy.
Abstract
Autism is a highly heritable behavioral disorder. Yet, two decades of genetic investigation have unveiled extremely few cases that can be solely explained on the basis of de novo mutations or cytogenetic abnormalities. Vertical viral transmission represents a nongenetic mechanism of disease compatible with high parent-to-offspring transmission and with low rates of disease-specific genetic abnormalities. Vertically transmitted viruses should be found more frequently in the affected tissues of autistic individuals compared to controls. Our initial step was thus to assess by nested polymerase chain reaction (PCR) and DNA sequence analysis the presence of cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes simplex virus type 1 (HSV1), herpes simplex virus type 2 (HSV2), human herpes virus 6 (HHV6), BK virus (BKV), JC virus (JCV), and simian virus 40 (SV40) in genomic DNA extracted from postmortem temporocortical tissue (Brodmann areas 41/42) belonging to 15 autistic patients and 13 controls. BKV, JCV, and SV40 combined are significantly more frequent among autistic patients compared to controls (67% versus 23%, respectively; P < .05). The majority of positives yielded archetypal sequences, whereas six patients and two controls unveiled single-base pair changes in two or more sequenced clones. No association is present with the remaining viruses, which are found in relatively few individuals (N <or= 3). Also polyviral infections tend to occur more frequently in the brains of autistic patients compared to controls (40% versus 7.7%, respectively; P = .08). Follow-up studies exploring vertical viral transmission as a possible pathogenetic mechanism in autistic disorder should focus on, but not be limited to, the role of polyomaviruses.
Comment in
Polyomaviruses and autism: more than simple association? [J Neurovirol. 2010]
PMID: 20345322 [PubMed - indexed for MEDLINE]
Publication Types, MeSH Terms, Substances
LinkOut - more resources

sheme
19th October 2013, 17:58
Here is one more for the file

https://goodhealthhelpdesk.com/index.php?/News/NewsItem/View/52/it-takes-guts-to-cure-autism

Jul
30

It takes Guts to Cure Autism.
Posted by Pedro Alvarez on 30 July 2013 07:06 PM



Health News (Week 30 - 2013)
By Robert Redfern

Of course I am not talking about bravery or determination but a healthy digestive system.

As well as Autism, I also include ADHD, ADD and Asperger’s – these are all other manifestations of a Gut/Brain disorder. The knowledge of this is not new (how the brain is linked to the gut). Hippocrates in ancient Greece said, “let food be thy medicine and medicine be thy food”.

There have been many studies on Autism and the digestive system. James Adams -- director of just one Autism/Asperger's Research Program said "One of the reasons we started addressing this topic is the fact that autistic children have a lot of GI problems that can last into adulthood," and Krajmalnik-Brown (a researcher for the program) said: "Studies have shown that when we manage these problems, their behavior improves dramatically."

There is no possible solution without a full diet change and this is especially difficult for Gut/Brain disorders as the determination needed to achieve a healthy gut is undermined by an abnormal fixation with unhealthy foods. Change is difficult for most human beings but it seems almost impossible for those with a Gut/Brain disorder or those caring for sufferers.

Especially children.

It is estimated that 15 years ago, around 1 in 10,000 kids had autism in the U.S.

Now it is estimated to be 1 in 50.

At this rate, what will it be in another 15 years’ time?

I know I’ve suffered from many of the symptoms of a Gut/Brain disorder and still do if I fall off the ‘healthy food wagon’. Many people feel like they are suffering, but also find it isn’t easy to change their diet – even if their life depends upon it. That’s because it can be difficult for some to change a lifetime of poor dietary choices.

The topic for this week’s newsletter came to me while watching a programme of a guy whose health was so bad he decided to consume only juiced vegetables and fruits for 60 days.

Not only did he lose lots of weight, get off his prescription drugs and look much healthier but one of his employees in his business pointed out his thinking and clarity of decision making had considerably improved.

I have no doubt that since he was only eating (juicing) raw fresh foods he was also taking in friendly bacteria as well as feeding the existing friendly bacteria which would accelerate his recovery (plus he had cut out dairy, carbs etc). Maybe the simple solution is to do anything we can to improve our gut, then everything after that may become much easier?

Easy steps for a healthy Gut/Brain (all supported by studies), include:

Taking a powerful Probiotic such as Prescript Assist, which can be opened and mixed with any food. Studies show the brain is affected positively with this
Taking specific relaxation supplements such as RelaxWell, to help with the anxiety that change causes and for a more relaxed sleep (opened and mixed for easy use).
Taking critical nutrients missing from the diet including Nascent Iodine Drops (4 drops x 4 times per day in a little water), and a good multivitamin such as Active Life (90 liquid vitamins in one)/MaxiVision containing selenium as a critical co-factor of Iodine.
Taking Coconut Oil for its effective MCT's is helpful and is good for mixing in foods such as ‘Paleo cookies’.
Krill Oil, Fish Oil complex or Hemp Oil for vegans.
Ancient Minerals Magnesium OIL Lotion
A better alternative is Magnesium Oil with added plant derived Melatonin (see studies at end)
Diet is the one solution that will make the biggest change. The diet that makes a dramatic difference is the ‘My Really Healthy Foods’ diet. There are lots of other recipes on the internet and you can find them by searching on ‘Ketogenic’ recipes and ‘Paleo’ recipes.

When it comes to children, get the mixing bowl out and start making the ‘Olivia's Choclate Brownies’ and ‘Ann’s Chocolate Cake’. There are many delicious desserts that will help to sweeten the change!

Please help by sending me your ‘Really Healthy Foods’ ideas that a child suffering with Gut/Brain disorder may find acceptable. Email this directly to me.

Questions and advice should come via Contact Me at the top, Robert’s Questions and then Next.


With kind regards,


Robert Redfern
Nutritionalist, Author & Broadcaster
www.GoodHealthHelpDesk.com


PS.
The initial cause of Gut/Brain disorders arises from lack of friendly bacteria available at birth or in the first year. It is also likely to be compounded by vaccinations, the latest studies confirm. The good news it is a dysfunction - not a life sentence.

Studies:
Iodine Deficiency Linked to Autisim In a number of countries with reported increases in autism there has been a concomitant increase in the prevalence of iodine deficiency.
(3 4 5) Another line of evidence is the effect of iodine deficiency on brain development and the findings in some children with autism. Iodine deficiency during the prenatal period has been associated with a number of adverse effects on the brain resulting in a continuum of effects from mild to severe depending on the degree of iodine deficiency, from lowered IQ to severe mental retardation, i.e., cretinism. The mechanism of iodine deficiency is that insufficient levels of iodine lead to an imbalance in thyroid hormone metabolism with a decrease in circulating thyroxin (T4) in both the pregnant mother and the fetus. This results in irreversible changes in brain architecture such as less dense neural connections.
(6) It has been reported that some children with autism have “underconnectivity” in certain regions of the brain.
(7) http://www.bmj.com/rapid-response/2011/10/30/iodine-deficiency-cause-autism

According to World Health Organization, in 2007, nearly 2 billion individuals had insufficient iodine intake, a third being of school age. ... Thus iodine deficiency, as the single greatest preventable cause of mental retardation, is an important public-health problem."

Melatonin for sleep in children with autism: a controlled trial examining dose, tolerability, and outcomes. Malow B, Adkins KW, McGrew SG, Wang L, Goldman SE, Fawkes D, Burnette C.
Source
Sleep Disorders Division, Department of Neurology and Kennedy Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. beth.malow@vanderbilt.edu Supplemental melatonin has shown promise in treating sleep onset insomnia in children with autism spectrum disorders (ASD). Twenty-four children, free of psychotropic medications, completed an open-label dose-escalation study to assess dose-response, tolerability, safety, feasibility of collecting actigraphy data, and ability of outcome measures to detect change during a 14-week intervention. Supplemental melatonin improved sleep latency, as measured by actigraphy, in most children at 1 or 3 mg dosages. It was effective in week 1 of treatment, maintained effects over several months, was well tolerated and safe, and showed improvement in sleep, behavior, and parenting stress. Our findings contribute to the growing literature on supplemental melatonin for insomnia in ASD.

Tesla_WTC_Solution
23rd October 2013, 03:58
http://www.autismspeaks.org/science/grants/glia-pathology-autism

Glia Pathology in Autism

Status: Completed

Investigator: Ordway, Gregory

Institution: East Tennessee State University

Grant Amount: $119,663.00

Grant Term: 2 years

Award Type: Pilot

City: Johnson City

State: TN

Country: United States

Year: 2010

Website: http://www.etsu.edu

Description
It is inherently difficult to devise targeted treatment for autism when little is known about how the brain is different in individuals with autism versus neurotypical individuals. The development of better treatments for autism will be facilitated greatly by the identification of precise molecular pathology of the human brain in individuals with autism. Several previous studies of individuals with autism have shown that there is reduced activity in a specific brain region called the anterior cingulate cortex, an area of the brain that regulates social interaction. This area of the brain has a complex circuitry that involves among others, two principal cellular players, glial cells and pyramidal neurons. Glial cells are often considered to be helper cells to neurons. However, many recent advances have shown that several brain disorders are characterized by pathology of glia, and numerous studies demonstrate that glia play a major role in the transmission of information between neurons in the brain. This study will examine a specific type of glia, astrocytes, in the anterior cingulate cortex. The investigators believe that circuitry dysfunction in the anterior cingulate cortex may underlie disruption of social interactions, a core feature of autism. Since astrocytes play a major role in regulating neurotransmission in the cortex, and because there is evidence of deficits in astrocyte markers in autism, the specific hypothesis of this proposal is that glial dysfunction in autism directly contributes to altered neurotransmission in anterior cingulate cortex. This pilot study measures the levels of expression several genes that will provide an index of neurotransmission in the anterior cortex. Gene expression in two distinct cell types in the brain will be studied using a high technology method of laser capture microdissection along with traditional molecular biological techniques. The research represents a novel exploration of non-neuronal elements (i.e., astrocytes) of neural transmission in autism, and has the potential to facilitate the identification of new specific molecular pathologies. Knowledge of these pathologies will contribute directly or indirectly to the development of novel and improved treatments for autism.


http://sfari.org/news-and-opinion/conference-news/2012/society-for-neuroscience-2012/video-connecting-astrocytes-to-autism

Video: Connecting astrocytes to autism
E-mail Print Share This Virginia Hughes
13 October 2012
The great majority of researchers studying the neuroscience of autism focus on neurons, brain cells that pass messages to each other via chemical and electrical signals. That makes sense, as many genes linked to the disorder function at the synapse, or junction between neurons.

But neurons make up just ten percent of cells in the human brain. The rest, called glia — from the Greek word for glue — were for decades thought of simply as support cells for neurons.

In the past few years, however, researchers have discovered that glia play a direct role in cell communication and are involved in many brain disorders, including autism-related syndromes.

Take, for example, the star-shaped glia called astrocytes, which wrap themselves around synapses. In 2005, Ben Barres’s team at Stanford University showed that developing neurons must be in the presence of astrocytes (or the chemicals they secrete) in order to form synapses. “Glia are literally acting as an on/off switch for synapse formation,” Barres says.

SFARI.org sat down with Barres on Saturday morning at the 2012 Society for Neuroscience annual meeting in New Orleans. Barres talked about a new project in which he and colleague Ricardo Dolmetsch are studying astrocytes in culture by reprogramming stem cells from children with autism.




http://en.wikipedia.org/wiki/Hepatic_encephalopathy

There are various explanations why liver dysfunction or portosystemic shunting might lead to encephalopathy. In healthy subjects, nitrogen-containing compounds from the intestine, generated by gut bacteria from food, are transported by the portal vein to the liver, where 80–90% is metabolised through the urea cycle and/or excreted immediately. This process is impaired in all subtypes of hepatic encephalopathy, either because the hepatocytes (liver cells) are incapable of metabolising the waste products or because portal venous blood bypasses the liver through collateral circulation or a medically constructed shunt. Nitrogenous waste products accumulate in the systemic circulation (hence the older term "portosystemic encephalopathy"). The most important waste product is ammonia (NH3). This small molecule crosses the blood–brain barrier and is absorbed and metabolised by the astrocytes, a population of cells in the brain that constitutes 30% of the cerebral cortex. Astrocytes use ammonia when synthesising glutamine from glutamate. The increased levels of glutamine lead to an increase in osmotic pressure in the astrocytes, which become swollen. There is increased activity of the inhibitory γ-aminobutyric acid (GABA) system, and the energy supply to other brain cells is decreased. This can be thought of as an example of brain oedema of the "cytotoxic" type.[11]

Despite numerous studies demonstrating the central role of ammonia, ammonia levels don't always correlate with the severity of the encephalopathy; it is suspected that this means that more ammonia has already been absorbed into the brain in those with severe symptoms whose serum levels are relatively low.[1][2] Other waste products implicated in hepatic encephalopathy include mercaptans (substances containing a thiol group), short-chain fatty acids and phenol.[2]

Numerous other abnormalities have been described in hepatic encephalopathy, although their relative contribution to the disease state is uncertain. Benzodiazepine-like compounds have been detected at increased levels as well as abnormalities in the GABA neurotransmission system. An imbalance between aromatic amino acids (phenylalanine, tryptophan and tyrosine) and branched-chain amino acids (leucine, isoleucine and valine) has been described; this would lead to the generation of false neurotransmitters (such octopamine and 2-hydroxyphenethylamine). Dysregulation of the serotonin system, too, has been reported. Depletion of zinc and accumulation of manganese may play a role.[1][2] Inflammation elsewhere in the body may precipitate encephalopathy through the action of cytokines and bacterial lipopolysaccharide on astrocytes.[4]

Tesla_WTC_Solution
23rd October 2013, 04:01
http://questioning-answers.blogspot.com/2012/04/short-chain-fatty-acids-and-ammonia-in.html

Views on autism research and other musings.

Friday, 27 April 2012

Short chain fatty acids and ammonia in autism
It is perhaps apt that Jon Brock over at Cracking the Enigma recently posted about the Australasian Society for Autism Research highlighting the various links being forged regarding autism research in that part of the world. Apt because there are several very good autism research groups producing findings which have some potential real-world application to autism, in that part of the World. I speak in particular of the team based at the Sansom Institute for Health Research based at the University of South Australia. Members of UNISA recently publishing a fine review of how glutathione and relations show quite a consistent relationship to cases of autism. Autism research movers and shakers please take note.

Indeed another paper published by Wang and colleagues* adds to the repertoire, suggesting that levels of fecal short chain fatty acids (SCFAs) and ammonia were higher in their cohort of children with autism compared to asymptomatic controls and hence showing alteration in the fermentation process.

As a sort of introduction to SCFAs and fermentation, readers might find this article by Topping & Clifton** (full-text) and this article by Macfarlane & Macfarlane*** (full-text) to be of interest. Basically, think carbohydrates and gut bacteria and eventually you head the direction of SCFAs. If you happen to brew your own beer, fermentation might not necessarily be a strange concept alongside memories of 'auto-brewery syndrome' (not personal memories I might add).

Unfortunately I can't post a link to the full-text but here are a few details:

Based on the collective studies of Dr Wang's PhD (scroll down to see her thesis details), this study looked at fecal specimens from a relatively small group: 23 children (mean age ~ 10 years) diagnosed with ASD compared with 31 age-matched controls.
Although not everyone's choice of biological medium to work with, fecal samples - as in poo samples - were analysed via various methods including colorimetry (ammonia) and gas chromatography (SCFAs). Other compounds such as p-cresol were analysed via liquid chromatography.
Results: fecal concentrations of total SCFAs were elevated in autism samples (p=0.012) as were levels of ammonia (p=0.007). Interestingly no elevation was observed in levels of p-cresol in autism samples as has previously been described.
More specifically with individual SCFAs, some interesting compounds cropped up as being elevated in autism samples including: propionic acid, butyric and isobutyric acids and valeric and isovaleric acids. Indeed out of the battery of SCFAs analysed, only caproic acid showed no significant difference between the groups.
The authors conclude that fecal levels of these large bowel fermentation products might tie into the accompanying gastrointestinal (GI) findings observed in some children with autism and differences in the bacteria inhabiting the darkest recesses.

There are some obvious caveats to accompany this latest study. Aside from participant numbers being relatively small and covering quite a lot of chronological age in childhood, and the slight discrepancy in controlling for gender, there was quite a bit of 'overlap' when it came to individual results from the autism and control groups. Indeed if I were to criticise at all, I perhaps would have like to have seen some plotted information on the dispersion of values obtained from individuals just to visualise and ensure that results were not skewed by a few outlier results. As has however been discussed recently, outliers in a heterogeneous condition like autism are very often a source of great interest.

This is not the first time that the words 'autism' and 'fermentation' have come to my attention. Quite a few years back I remember some interesting work being done at Cranfield University by Maria Pilar Bilbao Montoya as part of her higher studies. Working with gastroenterologist, John Hunter, Maria presented some initial work suggesting similar things in their cohort I believe. I might be wrong but I also remember that Dr Sophie Rosseneu might have had some unpublished work in this area also as a tie up with her findings on yeasts and autism?

Memories aside, there are some interesting points to take from this research. SCFAs such as propionic acid (PA) have recently been seen in the autism research arena as per this paper (full-text) by El-Ansary and colleagues looking at what happens when you inject rats with PA in sizeable quantities. For those of you who are unimpressed with the proposed PA-gut-brain link, maybe a few other choice papers might be useful, here and here. And perhaps some evidence for the presence of PA in other biological fluids from cases of autism?

I've talked ammonia before on this blog with reference to some mitochondrial findings. Wang and colleagues look more to the GI effects of ammonia given that it was detected in stool samples and how this might tie into issues with gut permeability so commonly discussed. Indeed ammonia - the whole nitrogen balance - takes us back to some old friends, glutamine and glutamate, one of which has been making quite a bit of news lately (here's the paper abstract).

The big question has to be why the reported differences in this latest study? I can't give a specific answer to this question but given the interest in carbohydrate metabolism and autism, the suggestion of things like lactose intolerance, added to the growing research base on gut bacteria and autism, one has to suspect that the answer might lie, partially at least, somewhere in these regions.

* Wang L. et al. Elevated fecal short chain fatty acids and ammonia concentrations in children with autism spectrum disorder. Digestive Diseases and Sciences. April 2012
DOI: 10.1007/s10620-01202167-7

** Topping DL. & Clifton PM. Short-Chain Fatty Acids and Human Colonic Function: Roles of Resistant Starch and Nonstarch Polysaccharides. Physiological Reviews. 2001; 81: 1031-1064

*** Macfarlane S. & Macfarlane GT. Regulation of short chain fatty acid production. Proceedings of the Nutrition Society. 2003; 62: 67-72
Posted by Paul Whiteley at 12:53












http://articles.mercola.com/sites/articles/archive/2004/06/26/autism-malnutrition.aspx



Autism and Malnutrition: The Milk Connection
June 26, 2004 | 17,327 views


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By Linda Carlton
To understand autism we can begin this journey from what we have learned about how seemingly insignificant dietary changes can affect newborn primates. In October 1975, three Japanese scientists raised a group of infant primates. By artificial nursing, these primates were fed a casein powdered milk formula. When they modified the infant formula to reduce the content of protein and increased the lactose to supplement the appropriate number of calories, the primate infants developed abnormal behaviors such as stereotype rocking, fear, aggression, head banging and other autistic-like behaviors. Completely unaware of what they had discovered, the scientists had induced autism in a clinical setting.

Now, they were aware that by reducing the protein content they caused the infants to become malnourished. They also observed that without human contact some infants were much more impaired. They learned that the infants that received the standard solution were reared successfully. At that time they concluded that a protein deficiency had caused a decline in physical and mental growth. Subsequent studies have supported this, whereby protein deficiency does cause developmental delay.

Autism Versus Developmental Delay

But it is important to know which symptoms are truly autistic and which are that of developmental delay. These disorders are often used interchangeably, but they are very different. For example, hand flapping is an autistic symptom, but it is not a common characteristic of developmental delay. In developmental delay children are often slow to learn, and will quickly fall behind their peers. The symptoms of these primates were more than just symptoms of developmental delay--they were symptoms of autism.

The most important information we have about these infant primates is that the researchers had also increased the lactose content in their diet. If the quantity of protein matched that of the quantity of lactose, this might not have occurred, or it might also have occurred if they had been fed too much protein. The standard formula given to the infant primates that were reared successfully were given the same amount of lactose, and what would have been the normal amount of protein for these size mammals.

Lactose and Autism

Lactose is the key to unraveling what happened to these infants. Bacteria use lactose, or milk sugar, as a nutrient base. Bifidobacteria and clostridia use lactose, and they often describe these strains of bacteria as lactose-fermenting bacteria. One difference in Bifidobacteria and Clostridia is that only one can produce significant amounts of ammonia, only one can damage the intestines. Milk oligosaccharides contain lactose; they are fermented in the infant colon where they selectively stimulate the growth of Bifidobacteria. Clostridia are competitors of Bifidobacteria, and Clostridia produce ammonia. Ammonia and only ammonia produced from bacteria could have caused the aberrant behaviors.

The infant primates had developed symptoms of autism because there was protein restriction, milk proteins needed for ammonia detoxification, and not necessarily just casein. They were fed lactose and lactose ferments ammonia, producing bacteria. They were unable to detoxify on a protein-deficient diet. It is a simple formula:

Protein + Lactose = Normal Development
Low protein + High Lactose = Autism

But protein malnutrition does not equal autism nor does lactose feeding equal autism. However,

Protein malnutrition + high-lactose feeding + (the unknown factor) = Autism

There has to be an unknown factor for this to occur, a combination of things that all relate to one another. The unknown factor can be found by testing these three variables. We have to review other information that we have on children with autism to give us the correct answer to the unknown factor.

A low-protein diet offsets a nitrogen balance to detoxify ammonia, whereas lactose feeding ferments bacteria. The only variable that could account for the unknown factor is ammonia. In autism, there are signs of ammonia detoxification, for example when GABA and nitric oxide are increased. So instead of developing overt ammonia toxicity, they are able to detoxify this excess ammonia. As encouraging as this sounds it still depletes cellular energy. Many parents can recall 'staring spells' as the first behavioral change in a child prior to autistic regression. This can be the first sign of increased blood ammonia.

Other symptoms found in children with only minimal increases in blood ammonia were:

Developmental regression
Loss of acquired speech
Stereotype hand movements
Myoclonic seizures
Generalized epileptic discharges
Repetitive behaviors
Sensory dysfunction
Auditory and visual hallucinations
Finegold and his colleagues have published three studies on children with autism. The first study was with the use of antibiotics. The second study of stool specimens indicated a vast overpopulation of Clostridia in children with autism. Many physicians use antibiotics for treatment of elevated blood ammonia to kill the ammonia-producing bacteria. Antibiotics have produced dramatic effects in children with autism, however this treatment did inevitably fail. Experiments with fermented foods after antibiotic treatments have been somewhat successful in preventing relapsing Clostridial infections.


Chris Rock: Never Scared (2004)
00:49:32 I'm talking about the white family that owns all the Similac. Those rich mother****ers.

Time - Phrase
00:49:24 "Bling-bling!"

00:49:28 I'm not talking 'bout rich, I'm talking 'bout wealth, OK?

00:49:32 I'm talking about the white family that owns all the Similac. Those rich mother****ers.

00:49:38 I'm talking about the white family that owns the colour blue. Those rich bastards.

00:49:45 I ain't talking 'bout Oprah, I'm talking 'bout Bill Gates, OK?

Tesla_WTC_Solution
3rd November 2013, 20:01
A thread on this topic exists at : http://projectavalon.net/forum4/showthread.php?65092-Transduction-and-Modern-Illnesses-Can-Wild-Strains-Gene-Swap-with-Tamed-Ones--Autism.-&p=752909#post752909

but I wanted to link it here because it's key to autism research.

http://www.ncbi.nlm.nih.gov/pubmed/9881820

Med Hypotheses. 1998 Aug;51(2):133-44.
Autism and Clostridium tetani.
Bolte ER.
Abstract
Autism is a severe developmental disability believed to have multiple etiologies. This paper outlines the possibility of a subacute, chronic tetanus infection of the intestinal tract as the underlying cause for symptoms of autism observed in some individuals. A significant percentage of individuals with autism have a history of extensive antibiotic use. Oral antibiotics significantly disrupt protective intestinal microbiota, creating a favorable environment for colonization by opportunistic pathogens. Clostridium tetani is an ubiquitous anaerobic bacillus that produces a potent neurotoxin. Intestinal colonization by C. tetani, and subsequent neurotoxin release, have been demonstrated in laboratory animals which were fed vegetative cells. The vagus nerve is capable of transporting tetanus neurotoxin (TeNT) and provides a route of ascent from the intestinal tract to the CNS. This route bypasses TeNT's normal preferential binding sites in the spinal cord, and therefore the symptoms of a typical tetanus infection are not evident. Once in the brain, TeNT disrupts the release of neurotransmitters by the proteolytic cleavage of synaptobrevin, a synaptic vesicle membrane protein. This inhibition of neurotransmitter release would explain a wide variety of behavioral deficits apparent in autism. Lab animals injected in the brain with TeNT have exhibited many of these behaviors. Some children with autism have also shown a significant reduction in stereotyped behaviors when treated with antimicrobials effective against intestinal clostridia. When viewed as sequelae to a subacute, chronic tetanus infection, many of the puzzling abnormalities of autism have a logical basis. A review of atypical tetanus cases, and strategies to test the validity of this paper's hypothesis, are included.
PMID: 9881820 [PubMed - indexed for MEDLINE]

_____________________________________________

I told a fellow in my autism support group that Clostridia is behind some cases of autism, without knowing why, and now I know exactly why -- the infection is sub-acute and gradually poisons the brain without the typical symptom of paralysis.

Tesla_WTC_Solution
24th November 2013, 17:07
http://sfari.org/news-and-opinion/viewpoint/2012/maternal-anti-brain-antibodies-may-play-a-role-in-autism

Maternal anti-brain antibodies may play a role in autism
E-mail Print Share This Betty Diamond, Lior Brimberg, Peter Gregersen
21 February 2012

Self destruction: Antibodies carried in the blood of mothers of children with autism (top), but not those of mothers of typically developing children (bottom) attack proteins in mouse brains.

The possibility that autoimmune mechanisms are a contributing factor in autism spectrum disorders has been entertained for decades, ever since early studies suggested that individuals with autism have a family history of autoimmune disease1,2.

Much of the early data were acquired from a fairly small number of individuals with autism. However, a 2009 Danish study examined autoimmune disorders in more than 600,000 children born between 1993 and 2004, and found an association between autism and both rheumatoid arthritis and celiac disease1. In fact, the study concluded that the risk of autism more than doubles for children who have a mother with one of these disorders.

The presence of autoantibodies, which are immune proteins that mistakenly attack the body’s own cells, in both diseases raises the possibility of a relationship between maternal autoantibodies and autism. In this model, maternal autoantibodies cross the placenta and enter the fetal brain, leading to alterations in its development. A variety of data published in the past few years provide evidence that such a model is biologically plausible.

The passage of maternal antibodies across the placenta is a well-known mechanism for fetal immune protection. Maternal antibodies reach all fetal tissues, even the brain. In adults, the entry of circulating soluble molecules and cells into brain tissue is limited by the blood-brain barrier, but in recent years it has become increasingly clear that the brain is less of an immune-privileged organ than it was previously considered to be.

In the fetus, the blood-brain barrier is not fully formed, making the developing brain vulnerable to blood-borne substances. In fact, acquired changes or genetic impairments in cognition and behavior have been shown to be a consequence of circulating brain-specific antibodies that can alter function if they gain access to brain tissue3.

Case studies:

The children of individuals with systemic lupus erythematosus (SLE) provide compelling data supporting this hypothesis. Congenital heart block, a type of arrhythmia, and skin rash are clearly transmissible to children by autoantibodies that are commonly present in women who have SLE.

The children of women with SLE also have a high incidence of learning disorders4. This effect has been linked to autoantibodies in mice, but not in humans, however. Intriguingly, many anti-DNA antibodies that are characteristic of SLE cross-react with the N-methyl-D-aspartate receptor (NMDAR), which is involved in learning and memory5.

We have shown that pregnant female mice harboring DNA- and NMDAR-specific antibodies have pups with abnormal fetal brain development. When the pups are born, their reflexes don’t develop as quickly as those of controls and, as adults, they have selected impairments in cognitive tasks6.

Several investigators have identified the presence of antibodies that bind to human fetal brain tissue in a subset of women who have children with autism7,8. When researchers gave these antibodies to pregnant mice and monkeys, they caused abnormal behavior in their offspring9.

In a 2003 study, researchers gave serum with anti-brain antibodies from mothers of children with autism to pregnant mice. The offspring had deficits in social behavior and motor skills, as well as cerebellar abnormalities10.

In a subsequent study, pregnant mice were given immunoglobulin antibodies isolated from the blood of mothers of children with autism. In this case, the offspring were more anxious during adolescence, had alterations in sociability and were more sensitive to noise than controls were11.

Researchers have also administered similar antibodies to pregnant rhesus monkeys. The offspring have more social deficits, motor activity and repetitive behaviors compared with offspring born to monkeys given immunoglobulin from mothers of typically developing children12.

The results from these studies suggest that maternal antibodies targeting the brain can affect brain development in their offspring, resulting in altered cognition, behavior and motor skills.

Risk rate:

By studying families in the Simons Simplex Collection (SSC), we have confirmed that mothers of children with autism are five times more likely to have anti-brain antibodies than are members of a control group consisting of healthy women of childbearing age. The SSC is a database of genetic and clinical information from families that have one child with autism, and unaffected parents and siblings, funded by SFARI.org’s parent organization.

Anti-nuclear antibodies, which are directed against the cell’s nucleus, are characteristic of many autoimmune diseases. We found that they are elevated in the blood of mothers of children with autism who also carry anti-brain antibodies compared with those who do not have anti-brain antibodies. This is consistent with the theory that autoimmunity predisposes mothers to having brain-reactive antibodies and giving birth to children with autism.

Interestingly, women with rheumatoid arthritis are as likely to have anti-brain antibodies as are mothers of children with autism. We are investigating whether genetic variants that have been linked to rheumatic arthritis and celiac disease are present in women who have both anti-brain antibodies and a child with autism.

Confirming an immune mechanism for some proportion of autism cases may help identify at-risk pregnancies, by allowing pregnant women or women planning to become pregnant to be screened for harmful anti-brain antibodies. It could eventually lead to the development of drugs that block these antibodies, thereby preventing autism from developing in vulnerable children.

These observations suggest that genetic studies in autism should be integrated with investigations into environmental exposures, including the maternal immune repertoire, in order to fully understand the genetic susceptibility of autism. Studying the targets of harmful anti-brain antibodies may also provide insights into disease mechanisms and pathways — which is a top priority for our future studies.

Betty Diamond is head of the Center for Autoimmune and Musculoskeletal Disorders at The Feinstein Institute for Medical Research in Long Island, New York. Lior Brimberg is a postdoctoral fellow in her laboratory. Peter Gregersen is head of the Robert S. Boas Center for Genomics and Human Genetics at the Feinstein Institute.

References:

1: Atladóttir H.O. et al. Pediatrics 124, 687-694 (2009) PubMed

2: Keil A. et al. Epidemiology 21, 805-808 (2010) PubMed

3: Diamond B. et al. Nat. Rev. Immunol. 9, 449-456 (2009) PubMed

4: Lahita R.G. Psychoneuroendocrinology 13, 385-396 (1988) PubMed

5: DeGiorgio L.A. et al. Nat. Med. 7, 1189-1193 (2001) PubMed

6: Lee J.Y. et al. Nat. Med. 15, 91-96 (2009) PubMed

7: Croen L.A. et al.. Biol. Psychiatry 64, 583-588 (2008) PubMed

8: Singer H.S. et al. J. Neuroimmunol. 194, 165-172 (2008) PubMed

9: Enstrom A.M. et al. Curr. Opin. Investig. Drugs 10, 463-473 (2009) PubMed

10: Dalton P. et al. Ann. Neurol. 53, 533-537 (2003) PubMed

11: Singer H.S. et al. J. Neuroimmunol. 211, 39-48 (2009) PubMed

12: Martin L.A. et al. Brain Behav. Immun. 22, 806-816 (2008) PubMed

Related Content:

http://www.ageofautism.com/2013/07/maternal-antibodies-and-autism.html

Maternal Antibodies and Autism and Flu Shots Oh Why?

Vax PregnantBy Teresa Conrick

The research on maternal antibodies as a cause of some cases of autism continues to grow. From TIME this week: "Mother’s Antibodies May Explain a Quarter of Autism Cases"

In a study published in Translational Psychiatry, researchers report that 23% of all cases of autism may result from the presence of maternal antibodies that interfere with fetal brain development during pregnancy. The work builds on a 2008 study from the same scientists that first described the group of antibodies in mothers-to-be.

This is interesting and important work as we continue to see autism as a disorder with roots to the immune system. It did make me wonder if it was possible that the maternal immune activation discussed here as a cause in 23% of the cases could correlate to immune activation created artifically by influenza vaccination. It seemed a valid point and one worth investigating especially when I saw this, also in that TIME article:

The antibodies belong to a class of compounds called autoantibodies, which are immune cells that the body makes to target — often mistakenly — its own cells. Scientists do not know why or when the mothers produce these antibodies, which appear to monkey with normal nerve development in the fetal brain by interfering with their growth, migration and genetic replication. It is possible that infections during pregnancy — a known risk factor for autism —can prompt the immune system to produce them. Exposure to toxic chemicals can also cause immune defenders to mistake healthy cells for invaders, Van de Water notes.


Note the last two sentences - the first related to infection in pregnancy and the second to toxic chemicals.

Can infection in pregnancy cause autism? I wondered about that and did some background reading and wrote this article in January, "Can Influenza Vaccines Cause Maternal Immune Activation Linked To Autism?

Mothers who get the flu while pregnant could risk affecting their baby's brain, which might lead to 'infantile autism' in their child.

A Danish study shows that children were slightly more likely to be diagnosed with the condition before the age of three if their mother had the flu.

Researchers claim that when the mother's immune system is triggered - for example, when they have an influenza virus - it is possible that the foetus' developing brain could be affected.
But they have clarified that pregnant women and mothers should not be concerned by the findings, as only a tiny portion of those who had influenza gave birth to children with 'infantile autism' and that the research was so limited and early that no concrete findings had been discovered."

Interesting. So why is it then that in 1918, the Great Influenza Epidemic swept the world, but yet autism was not identified nor described until Dr. Leo Kanner diagnosed it with those first eleven children born in the 1930's?:

“Since 1938 , there have come to our attention a number of children whose condition differs so markedly and uniquely from anything reported so far that each case merits—and, I hope will eventually receive—a detailed consideration of its fascinating peculiarities...."

So let's look at the mechanism described:

"..the pro-inflammatory cytokine interleukin 6, which is known to induce placental inflammatory processes46 and has been shown to mediate the neurodevelopmental effects of gestational inflammation.47 It is possible that such inflammatory processes could be related to the production of maternal antibodies that recognize fetal antigens through maternal-fetal cross talk48 or that maternal antibody to antigen interactions may precipitate inflammation-induced neurodevelopmental alterations similarly to bacterial or viral challenge."



That is interesting and similar to what I found in my reading, which brings me to the second method identified as a causative factor in producing these maternal antibodies -- toxic chemicals. What else can cause Interleukin 6 (IL-6) a pro-inflammatory cytokine, to be produced?
"Effect of influenza vaccine on markers of inflammation and lipid profile"

Despite wide use of the influenza vaccine, relatively little is known about its effect on the measurement of inflammatory markers....We drew blood from 22 healthy individuals 1 to 6 hours before they were given an influenza vaccination and 1, 3, and 7 days after the vaccination...Our findings show that the influenza vaccination causes transient changes in select markers of inflammation and lipids. Consequently, clinical and epidemiologic interpretation of the biomarkers affected should take into account the possible effects of influenza vaccination.

Inflammatory responses to trivalent influenza virus vaccine among pregnant women
In the U.S., seasonal trivalent influenza virus vaccine (TIV) is currently universally recommended for all pregnant women. However, data on the maternal inflammatory response to vaccination is lacking and would better delineate the safety and clinical utility of immunization.......Significant increases in CRP were seen at one and two days post-vaccination (ps<05). A similar effect was seen for TNF-α, for which an increase at two days post-vaccination approached statistical significance (p=.06). There was considerable variability in magnitude of response; coefficients of variation for change at two days post-vaccination ranged from 122% to 728%, with the greatest variability in IL-6 responses at this timepoint.......Trivalent influenza virus vaccination elicits a measurable inflammatory response among pregnant women. ......further research is needed to confirm that the mild inflammatory response elicited by vaccination is benign in pregnancy.

Can Thimerosal, the mercury used in vaccines as a preservative, be part of this picture? This past year, it was reported by the CDC about the total number of flu shots and then the Thimerosal-free flu shots:

"145 million doses of influenza vaccine .... 62 million doses of thimerosal-free or preservative-free (trace thimerosal) influenza vaccine."

Could any of these women, who were part of this study, have had a flu shot? It looks as if Thimerosal in any of those flu vaccines could possibly cause an increase in IL-6, the same IL-6 described above in the study -- "the pro-inflammatory cytokine interleukin 6, which is known to induce placental inflammatory processes46 and has been shown to mediate the neurodevelopmental effects of gestational inflammation...."

Thimerosal is shown to have profound effects on the immune system and is in many of the influenza vaccines:

"When thimerosal, at a concentration as low as 20 parts per billion, alters the fidelity of normal calcium signals, dendritic cells show abnormal secretion of IL-6 cytokine - a potent chemical signal that initiates inflammatory responses."

It appears very possible that influenza vaccination, especially with Thimerosal, could start off this inflammatory process in a pregnancy. I need to mention too, that the percent in this study, the 23% who went on and had a child diagnosed with autism -- is in the ballpark of the percent of pregnant women who reportedly get a flu shot -" between 10 percent and one-quarter of women"
Another imperative reason we need this research and precautions is that I met one of the women in this study. She had a flu shot when pregnant.

Teresa Conrick is Contributing Editor to Age of Autism.


Posted by Age of Autism at July 22, 2013 at 5:45 AM in Teresa Conrick | Permalink | Comments (28)

Tesla_WTC_Solution
24th November 2013, 17:19
Wanted to point out: I received a flu shot in 2007, mere months before my son was born on Jan 1.
Some days afterwards, I ended up in the hospital because my fetus had stopped moving.
Years later, in 2013, doctors are starting to realize that maternal antibodies play a role in the brain protein loss typical of autism.
What we are wondering now, of course, is whether maternal exposure to influenza vaccine during pregnancy may have caused autoimmunity against fetal tissue.

It was almost as if my son had the flu himself after I got the vaccine.
What could make a healthy fetus stop moving for a week?

He was diagnosed with autism at age 1, shortly before second birthday.
We've always wondered if his babyhood shot regimen worsened his autism.

Tesla_WTC_Solution
24th November 2013, 21:07
http://www.medicinenet.com/flu_vaccination/patient-comments-859.htm

Patient Comments: Flu Vaccination - Side Effects


Comment from: skategirl, 65-74 Female (Patient)Published: March 07
I have gotten a yearly flu shot for years and had no problems. However, this year I was given the flu shot for seniors (I'm 68). I had a number of side effects with this one, including nausea, severe neck and shoulder pain on my left side. The neck and shoulder pain lasted for about a couple of weeks. I began to do some gentle exercise again after that, and the shoulder pain came back. It was severe and I was only able to sleep 4 or 5 hours at a time after taking Ibuprofen. I couldn't eat much because of the nausea and pain and lost weight. The second episode of shoulder pain also lasted two weeks. I also had tingling in my left arm and hand. I was given the shot in my right arm. I haven't had any pain in three weeks, and the tingling is almost gone now, so hope I'm over this. I'm not aware of anything I did to cause the pain, so believe it was the flu shot. It was scary as I'm not a sickly person & had never had anything like this. I'll never get another flu shot!
Related Medications: Ibuprofen


Comment from: Bev, 55-64 Female (Patient)Published: March 07
I received a flu shot in 09 just about killed me. I was passing out on leaving the exam room. I was wheeled back in the exam room where I felt extremely hot, a burning back up my back as if I was on fire. I was in terrible pain to the point of crying. I have a high tolerance for pain but this was something horrific. My heart was racing extremely fast my blood pressure dropped to almost nothing. I was given an injection to counter act the adverse reaction. Within 20 minutes I was feeling better. Months after this I was diagnosed with Rheumatoid Arthritis though no one in my family has had this. Now I read it could be linked to the flu shot. I am need of surgeries for knee replacements, I have pain in every joint in my body from the R/A. I have not taken a flu shot since but will regret doing so for the rest of my life.

http://www.hindawi.com/crim/rheumatology/2012/785028/


Case Reports in Rheumatology
Volume 2012 (2012), Article ID 785028, 3 pages
http://dx.doi.org/10.1155/2012/785028
Case Report
Rheumatoid Arthritis and Swine Influenza Vaccine: A Case Report

Gurjot Basra,1 Praveen Jajoria,2 and Emilio Gonzalez2
1Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA
2Division of Rheumatology, University of Texas Medical Branch, Galveston, TX 77555, USA

Received 3 April 2012; Accepted 15 June 2012

Academic Editors: D. Aeberli, J. V. Dunne, and F. Schiavon

Copyright © 2012 Gurjot Basra et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Rheumatoid arthritis (RA) is the most common chronic inflammatory joint disease. Multiple scientific articles have documented that vaccinations for influenza, MMR, and HBV, to name a few, could be triggers of RA in genetically predisposed individuals. However, there is limited data regarding the association of swine flu vaccine (H1N1) and RA. We report the case of a Mexican American female who developed RA right after vaccination with H1N1 vaccine. Genetically, RA has consistently been associated with an epitope in the third hypervariable region of the HLA-DR chains, known as the “shared epitope”, which is found primarily in DR4 and DR1 regions. The presence of HLA-DRB1 alleles is associated with susceptibility to RA in Mexican Americans. Hence, certain individuals with the presence of the “shared epitope” may develop RA following specific vaccinations. To our knowledge, this is the first reported case of RA following vaccination with the swine flu vaccine.

1. Introduction

Rheumatoid arthritis (RA) is the most frequent of all chronic inflammatory joint diseases characterized by pain, swelling, stiffness, and destruction of joints due to synovial inflammation and effusion resulting in disability. It affects 0.5–1% of population in industrialized world with annual incidence reported to be around 12–1200 per 100,000 [1]. Women are affected two to three times as often as men and peak age of onset is between the ages 30 and 55 but can occur at any age. The etiology of RA is multifactorial and includes hormonal, environmental, genetic, infectious, and other variables. RA is associated with the presence of an epitope in the third hypervariable region of the HLA-DR β chains, known as the “shared epitope." Individuals with the sequence leu-glu-lys-arg-ala in residues 67–74 have a much higher incidence of developing RA [2]. This sequence is found in DR4, DR14, and DR1 β chains. HLA-DRB1 allele is associated with susceptibility to RA in Mexican Americans while HLA-DRB1*08 appears to have a protective influence on RA susceptibility and disease severity in Mexican Americans.

It has been shown that the onset of rheumatic disease after vaccination signifies that the vaccine may trigger persistent autoimmune response in genetically predisposed individuals. Vaccinations that are suspected to cause RA include influenza, MMR, HBV, tetanus toxoid, typhoid, paratyphoid A and B (TAB), polio, diphtheria, and small pox [3]. HLA DR-4 was frequently present in the above-described patients, suggesting that genetically susceptible individuals are at increased risk for RA after vaccinations. However, there is no causal association between swine flu vaccination and RA onset that has been documented so far. We report a case of Mexican American female who develops RA after vaccination (H1N1) exposure which could possibly be due to her genetic susceptibly explained by above factors.

2. Case Report

A 33-year-old Hispanic female with no significant past medical history was referred to the rheumatology clinic in May 2010 by her primary care physician for having pain and swelling in multiple joints since November 2009. Patient received a seasonal flu shot in October and a week later, she noted some joint pain and aches in hands, wrists, and knees, which resolved within a few days and patient became asymptomatic. A month later, she received H1N1 (swine influenza) vaccine and a week after started experiencing joint pain, swelling, and stiffness in hand, wrist, elbow, shoulder, and knee joints. She also complained of significant morning stiffness that last for more than one hour. On physical examination she had bilateral synovitis in fourth and fifth metacarpophalangeal (MCP), second, and third proximal interphalangeal (PIP) joints, with prominent left ulnar styloid. She fulfilled most of the criteria for classification of RA based on American College of Rheumatology (ACR) guidelines.

Tesla_WTC_Solution
10th December 2013, 03:02
SUPER IMPORTANT:

Effie Trinket
Member
*
Offline
Posts: 1,392

Forced Flu Vaccine's planned for New York schoolchildren
« on: Today at 07:41:31 PM »
http://politicker.com/2013/12/protest-planned-against-last-minute-bloomberg-push-for-mandatory-flu-vaccines/

Autism advocates are set to protest tomorrow against a quiet effort by Mayor Michael Bloomberg’s administration to require annual flu vaccinations for all New York City schoolchildren.

On Wednesday, with just three weeks to go until he leaves office, Mr. Bloomberg’s controversial Board of Health is set to vote on new rules that would force children as young as six months old to be immunized each year before December 31 if they attend licensed day care or pre-school programs.

“Young children have a high risk of developing severe complications from influenza. One-third of children under five in New York City do not receive an annual influenza vaccination, even though the vaccine safely and effectively protects them against influenza illness,” the Health Department said in a statement. “This mandate will help protect the health of young children, while reducing the spread of influenza in New York City.”

The Board is stocked with mayoral appointees and controversial initiatives–from smoking bans to regulations on soda cup sizes–have sailed through with little opposition, angering a small, but passionate group of advocates who claim the vaccinations are potentially dangerous.

“The Bloomberg administration is wildly exaggerating the benefit of the flu shot and we think they are wildly underestimating the risks involved with it,” said John Gilmore, the executive director of the Autism Action Network, speaking more broadly than the controversial claim that links vaccines to autism.

“There are risks associated with every medical procedure,” he said, citing allergic reactions, toxic mercury used as a preservative and questions as to whether the Board’s move is legal given state government jurisdictions.

Mr. Gilmore’s organization is helping organize tomorrow’s protest. And though he doesn’t expect the Board’s vote to go his way, he hopes the rally will get Mayor-elect Bill de Blasio’s attention, potentially opening the door for a reversal once he takes office in January.

“This is basically to put the mayor-elect [on alert], make him aware that this is an issue that he’s going to have to deal with it. It’s not going to go away,” said Mr. Gilmore said, criticizing the way the Bloomberg administration has pushed the rules through. “He is kind of doing this in a stealth fashion. He just proposed this about 6 weeks ago. I don’t think there was any announcement.”

According to a Board of Health notice made public in September, influenza results in 20,000 hospitalizations and 30 to 150 deaths in children under 5 nation-wide each year.

Under the proposed rule, which had a public hearing in October, the vaccinations would be required “unless the vaccine may be detrimental to the child’s health, as certified by a physician licensed to practice medicine in this state, or the parent, parents, or guardian of a child hold genuine and sincere religious beliefs which are contrary to the practices herein required.”

________________________________________________________

http://www.freeinews.com/health/autism-symptoms-in-mice-decreased-with-probiotics-study-says

Researchers developed mice with autism-like symptoms by referring to a previous finding that severe viral infection during pregnancy seems to increase the risk the child will have autism. So, the researchers triggered an infection-like immune response in pregnant mice, which led to offspring with autism-like symptoms.

http://www.ncbi.nlm.nih.gov/pubmed/22235050

Lupus. 2012 Feb;21(2):175-83. doi: 10.1177/0961203311429817.
Autoimmune response following influenza vaccination in patients with autoimmune inflammatory rheumatic disease.

Perdan-Pirkmajer K, Thallinger GG, Snoj N, Čučnik S, Žigon P, Kveder T, Logar D, Praprotnik S, Tomšič M, Sodin-Semrl S, Ambrožič A.
Source

University Medical Centre Ljubljana, Department of Rheumatology, Ljubljana, Slovenia.

Abstract

Vaccines have undoubtedly brought overwhelming benefits to mankind and are considered safe and effective. Nevertheless, they can occasionally stimulate autoantibody production or even a recently defined syndrome known as autoimmune/inflammatory syndrome induced by adjuvants (ASIA). There is scarce data regarding autoimmune response after seasonal/influenza A (H1N1) vaccine in patients with autoimmune inflammatory rheumatic disease (AIRD). The objective of our study was therefore to determine autoimmune response in a large group of AIRD patients vaccinated against seasonal and/or H1N1 influenza. We conducted a prospective cohort study with a 6-month follow-up. Two-hundred and eighteen patients with AIRD (50 vaccinated against seasonal influenza, six against H1N1, 104 against both, 58 non-vaccinated controls) and 41 apparently healthy controls (nine vaccinated against seasonal influenza, three against H1N1, 18 against both, 11 non-vaccinated controls) were included. Blood samples were taken and screened for autoantibodies [antinuclear antibody (ANA), anti-extractable nuclear antigen (anti-ENA), anticardiolipin (aCL) IgG/IgM antibodies, anti-beta 2-glycoprotein I (anti-β2GPI)] at inclusion in the study, before each vaccination, 1 month after the last vaccination and 6 months after inclusion. For non-vaccinated participants (patients and healthy controls) blood samples were taken at the time of inclusion in the study and 6 months later. We report that after the administration of seasonal/H1N1 vaccine there were mostly transient changes in autoantibody production in AIRD patients and in healthy participants. However, a small subset of patients, especially ANA-positive patients, had a tendency towards anti-ENA development. Although no convincing differences between the seasonal and H1N1 vaccines were observed, our results imply that there might be a slight tendency of the H1N1 vaccine towards aCL induction. Although seasonal and H1N1 vaccines are safe and effective, they also have the potential to induce autoantibodies in selected AIRD patients and healthy adults. Follow-up of such individuals is proposed and further research is needed.
PMID: 22235050 [PubMed - indexed for MEDLINE]

_______________________________________________________

Adjuvants are experimental immune system irritants that without exception result in autoimmunity and misery in some portion of the vaccinated population.

If vaccines were crucial to human life, there would be no surviving Amish people left.

Tesla_WTC_Solution
10th December 2013, 03:10
all it takes is one bad jab and life as you know it can end in an instant.

Tesla_WTC_Solution
10th December 2013, 06:24
Here is a good one from a week or so ago!

J Autism Dev Disord. 2013 Nov 29. [Epub ahead of print]
Rigid-Compulsive Behaviors are Associated with Mixed Bowel Symptoms in Autism Spectrum Disorder.
Peters B, Williams KC, Gorrindo P, Rosenberg D, Lee EB, Levitt P, Veenstra-Vanderweele J.

Source
Vanderbilt University, 1601 23rd Avenue South, Suite 300, Nashville, TN, 37212, USA, brittany.peters@vanderbilt.edu.

Abstract

Based on clinical experience, we hypothesized that rigid-compulsive behaviors are associated with severe constipation and co-occurring diarrhea or underwear staining in children with autism spectrum disorder. Using data from the Autism Treatment Network, we evaluated the association between these gastrointestinal symptoms and measures of rigid compulsive behavior in children ages 2-17. Following statistical correction, four of five primary measures were significantly associated with constipation and diarrhea or underwear staining, including parental report of repetitive behavior, parental report of compulsive behavior, clinician diagnosis of obsessive-compulsive disorder, and report of rituals observed on the autism diagnostic observation schedule. This association could point to a causal connection between these symptoms or to a common biological pathway that impacts both gut and brain.

PMID: 24293040 [PubMed - as supplied by publisher]

Tesla_WTC_Solution
10th December 2013, 06:31
Heparan Sulfate Link to Autism and Leaky Gut, link to Hep B vaccine, pathogenicity of altered gut flora

http://coolinginflammation.blogspot.com/

Antibiotics Select for E. coli that Stick to Rectal Surface of Cattle
Pathogenic E. coli are not found throughout cattle fecal material, but rather they are only in the outermost surface layer. This outer layer of material contains bacteria from the surface of the rectum just as the cow pies are deposited. E. coli does not normally stick to this surface, because it lacks a protein, such as a hemagglutinin capable of binding to the surface polysaccharides, heparan sulfate. Antibiotics kill off the bacteria normally residing on the surface. As a member of the intestinal biofilm community, E. coli continually exchanges DNA/genes with other bacteria in the gut and picks up three useful genes, to become a pathogen:
Antibiotic resistance

Hemagglutinin for sticking to surfaces
Toxin to release nutrients from the intestinal walls.



________________________________________________________________

When your kid gets the Hep B vaccine, it can trade dangerous genes for surface proteins with other germs living in your child already.
E coli that would otherwise be harmless assumes genes that allow it to bind directly to the intestinal wall, leading to leaky gut, damaged vili, and chronic infection.

Constirrhea in a nutshell. autism too.

Heparan sulfate is found in the intestine, and also in the brain.

Depletion of heparan sulfate in mice is known to cause autism-like symptoms.

this is directly linked to the health of the gut.

Apparently BS is a pretty big deal when it has the wrong germs in it, lol

Tesla_WTC_Solution
10th December 2013, 06:40
http://healthyprotocols.com/2_vac_hep%20B.htm

__________________________________________________

I blogged about Heparan Sulfate on my website nuclearnuttery about two years ago,
saying that the binding mechanism of hepatitis B strips the human body of necessary proteins.
this is much more severe in infants, for obvious reasons (size)



according to google there are some recent research results in the area of linking autism to heparan sulfate.
i am hoping they go the extra mile and realize hep B could be directly involved in this unfortunate process of elimination of healthy children.

Autism, Sulphate, Sunshine, and Nutrition | Musings from the Chiefio
chiefio.wordpress.com/2013/02/.../autism-sulphate-sunshine-and-nutritio...‎

Feb 20, 2013 - Of special interest is a recent discovery that a postnatally induced heparan sulfate deficiency in the brain is capable of causing autistic behavior ...
Trends in Autism Research - Page 207 - Google Books Result
books.google.com/books?isbn=159454042X
O. T. Ryaskin - 2004 - ‎Medical
The glomerular basement membrane (GBM) of the kidneys contains heparan sulfate and chondroitin sulfate proteoglycans (Ehara et al., 1994). They are ...

Autism Link found in Children with Bone Disorders | Medical News ...
www.ivanhoe.com/channels/p_channelstory.cfm?storyid=29101‎
Mar 13, 2012 - "There is growing evidence that many autistic people have related genetic ... who are autistic might have similar defects in heparan sulfate.






http://chiefio.wordpress.com/2013/02/20/autism-sulphate-sunshine-and-nutrition/


Entropy 2012, 14(10), 1953-1977; doi:10.3390/e14101953
Review

Impaired Sulfate Metabolism and Epigenetics: Is There a Link in Autism?

Samantha Hartzell and Stephanie Seneff* email

Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge 02139, MA, USA
* Author to whom correspondence should be addressed.
Received: 28 September 2012; in revised form: 16 October 2012 / Accepted: 16 October 2012 / Published: 18 October 2012
(This article belongs to the Special Issue Biosemiotic Entropy: Disorder, Disease, and Mortality)

Abstract: Autism is a brain disorder involving social, memory, and learning deficits, that normally develops prenatally or early in childhood. Frustratingly, many research dollars have as yet failed to identify the cause of autism. While twin concordance studies indicate a strong genetic component, the alarming rise in the incidence of autism in the last three decades suggests that environmental factors play a key role as well. This dichotomy can be easily explained if we invoke a heritable epigenetic effect as the primary factor. Researchers are just beginning to realize the huge significance of epigenetic effects taking place during gestation in influencing the phenotypical expression. Here, we propose the novel hypothesis that sulfates deficiency in both the mother and the child, brought on mainly by excess exposure to environmental toxins and inadequate sunlight exposure to the skin, leads to widespread hypomethylation in the fetal brain with devastating consequences. We show that many seemingly disparate observations regarding serum markers, neuronal pathologies, and nutritional deficiencies associated with autism can be integrated to support our hypothesis.

Keywords: autism; epigenetics; cholesterol sulfate; DNA methylation; sulfotransferases; heparan sulfate; folate; cobalamin; zinc


http://www.ivanhoe.com/channels/p_channelstory.cfm?storyid=29101


Reported March 13, 2012
Autism Link found in Children with Bone Disorders

(Ivanhoe Newswire)-- Children with multiple hereditary exostoses (MHE), suffer from multiple growths in their bones that cause pain and disfigurement. However aside from the physical impairments, parents also notice that their children with MHE also experience autism-like social problems.

With the encouragement of parents, researchers at Sanford-Burnham Medical Research Institute are able to uncover the link between autism and MHE by using a mouse model of MHE to investigate cognitive function. They found that mice with a genetic defect that models human MHE show symptoms that meet the three defining characteristics of autism.

"There is growing evidence that many autistic people have related genetic defects, or defects that are exacerbated by this one," Yu Yamaguchi, M.D., Ph.D., professor in the Sanford Children's Health Research Center at Sanford-Burnham." Yamaguchi led this study, along with colleagues Fumitoshi Irie, Ph.D. and Hedieh Badie-Mahdavi, Ph.D., was quoted as saying.

In humans, MHE is caused by a mutation in one of two genes, Ext1 or Ext2. Together, these genes encode an enzyme necessary to produce heparan sulfate—a long sugar chain that helps bone cells grow and proliferate. In this study, Yamaguchi and his team used mice that lack the Ext1 gene in just a certain type of neuron to understand the mechanism of social problems in MHE patients.

The mice were tested for the three defining characteristics of autism: social impairment, language deficits, and repetitive behavior. The team found that the mutant mice were less social than normal mice. They also exhibited language deficiencies, as determined using ultrasound vocalization measurements, a well-characterized substitute for mouse language. Lastly, Yamaguchi's team took at look at repetitive behaviors in these mice. Using a board covered with holes, they observed that normal mice will poke their noses in many holes at random, while the mutant mice poke their noses in the same hole again and again.

This information clearly demonstrates what the parents of children with MHE have always suspected—the disease affects more than just bones. The genetic defect that causes skeletal deformities also causes social and cognitive problems.

Not all autistic children have MHE, nor are all MHE children autistic. But, according to Yamaguchi, there is evidence that some people who are autistic might have similar defects in heparan sulfate. This is the sugar chain that's defective in MHE, where it causes bone deformities and social deficits.

"There are a few studies that compared the genomes of healthy and autistic people and they revealed differences in some heparan sulfate-related genes," Yamaguchi was quoted as saying.

There are most likely many different genetic abnormalities that can lead to autism in the general population. This study and others now indicate that for some, the condition could be caused by mutations in genes encoding enzymes and proteins involved in making heparan sulfate.

Yamaguchi's team is now comparing DNA from autistic and non-autistic volunteers to look for mutations in heparan sulfate genes. So far the initial results have been encouraging.

"I can't emphasize enough how much it helped that the parents of kids with MHE got involved and supported this research," Yamaguchi said. "As parents, they noticed their kids had social problems that gave them challenges at school. School officials and other people didn't take these observations seriously—they usually just waved off the problems, assuming that the kids' bone deformities just make them shy. This latest research doesn't solve any bone issues for MHE patients, but it does help support what the parents always knew—these children need special care."

SOURCE: Proceedings of the National Academy of Sciences, March 2012.

Tesla_WTC_Solution
9th January 2014, 21:20
http://www.hightimes.com/read/marijuana-may-be-used-treat-autism

Marijuana May Be Used to Treat Autism
BY MIKE ADAMS · THU OCT 31, 2013

Recent studies indicate that compounds found in marijuana may be used to successfully treat autism.

Researchers at Stanford University say that the debilitating effects of autism are primarily caused by a gene mutation that blocks the body’s natural production of cannabinoids, called endocannabinoids, and hinders the way those molecules communicate with the brain.

In the study, researchers found that the mutation of the neurologin-3 gene, which is responsible for creating and sustaining normal communication between brain cells, appears to have a direct correlation to autism -- introducing derivatives of cannabis to the brain could ease symptoms associated with the disease.

Although the exact science revolving around how a disturbance in endocannabinoid signaling contributes to autism symptoms, researchers say there is significant evidence that suggest medical marijuana may be a viable treatment option for this condition.

Researchers from the University of Irvine in California believe the folks at Stanford may be on to something: because they, too, have discovered a link between endocannabinoids and autism.

In a study of mice with fragile X syndrome, it “showed dramatic behavioral improvements in maze tests measuring anxiety and open-space acceptance.” And because THC, the active compound in marijuana, stimulates the same receptors as the endocannabinoids, researchers concluded, “increasing natural marijuana-like chemicals in the brain can help correct behavioral issues related to fragile X syndrome, the most common known genetic cause of autism.”

A recent article published in the Autism Daily Newscast indicates that many families are already experimenting with marijuana as a treatment for their children’s autism -- as an alternative to other drugs with major side effects and questionable results.

Researchers add that while they do not advocate giving medical marijuana to children with autism, they believe their findings will lead to the development of important treatments for this devastating disease.

conk
10th January 2014, 17:36
From Dr. Robert Rowen, a well respected alternative physician:

Is Autism an Infectious
Disease?
Autism is such a huge problem nationwide
that I have repeatedly written about
it. I suspected vaccinations as a cause of
autism more than 15 years ago when I
first started seeing the disorder. Most
cases had a history of mental changes that
began within days to weeks of getting the
MMR vaccine (for measles, mumps and
rubella). Of course, the pundits and their
pediatricians said there was no connection.
Then Dr. Andrew Wakefield, a gastroenterologist
published his findings in 1998. Prof. John O’Leary, a pathologist,
published his findings in 1998. They
found live rubella virus in the intestines
of kids with autism. Do you think rubella
virus should be alive, well, and thriving in
and inflaming your intestines? Well,
today’s technology makes the diagnosis
even more specific.
A team of researchers at Wake Forest
University School of Medicine in North
Carolina has found the vaccine strain
itself (not the wild virus that we got as
kids) in autistic kids. It was found in 85%
of intestinal samples taken from the guts
of children with regressive autism. And
just as this information is making news,
you can count on opposition from “authorities.”
The British Department of Health
reiterated that MMR is safe.
I must tell you that I hurt really badly
when I see a case of autism. First, I know
that it didn’t have to happen. Next, it’s a
problem that will be with that person for
the next 75 years or however long he or
she lives. Not only will that child’s life be
stolen from him, but he will have to be
supported at someone’s expense all that
time. The parents will suffer most. You,
the taxpayer, may suffer next.
There’s plenty you can do about it.
First, no vaccines for you, of any kind!
We’ve gone over that many times in these
pages. Next, get this particular information
to anyone of childbearing years, especially
your family. I’ve never had the
chance to treat measles or rubella. But I
consider the results I’ve had with oxidation
therapy and IV vitamin C in infections
in children. I’ve seen acute mono
vanish in mere days with ozone therapy.
Treating any of the usual childhood diseases
will certainly be a cakewalk to trying
to repair a ravaged brain with wires
all crossed after the fact. And yes, I’ve
treated mumps with ozone therapy when
I was in Alaska.
The medical mob is NOT going to stop
vaccinations and end the autism epidemic.
There’s just too much vested financial interest. And do you think they could ever
admit that they were wrong? It’s up to us to
stop the carnage to our beloved youngsters.
We owe it to them and to society. They carry
a 1:150 risk of contracting the infectious disease
of autism and a much higher chance of
getting its milder cousin ADD/hyperactivity.
We have to stop the madness!
Ref: “U.S. scientists back autism link to MMR,”
AAPS, May 30, 2006; Beezy Marsh and Sally Beck,
Telegraph.co.uk May 28, 2006. http://www.telegraph.
co.uk/news/main.jhtml?xml=/news/2006/05/28/
wmmr28.xm.

Sorry about the way it copied over to the forum.

Tesla_WTC_Solution
11th January 2014, 00:28
Thank you, conk!

Did you know you can sometimes catch measles from changing baby diapers, if the baby was recently vaccinated?
It's possible. :(

__________________________________________________________

Please also check out the MTHFR folate-related mutation and these parents discussing the dangers of vaccinating a child carrying a folate abnormality:

http://mthfr.net/forums/topic/mthfr-and-vaccinesimmunizations-contraindicated/

March 7, 2012 at 3:42 am #1239

Emily
Dr. Ben –

Do you know of any research that you can point me to in regards to MTHFR and vaccines/immunizations. I know it is a stretch considering how little information on this is out there mainstream. I know it generally is thought of as being not advisable in those with MTHFR and my gut tells me not to do it, but I’m having trouble presenting our case to the pediatrician. Our pediatrician outright stated tonight that vaccines are not contraindicated in folks with MTHFR (and PANDAS, our sons other condition). My concern is his ability to detoxify heavy metals and methylation issues (due to MTHFR, Homozygeous C677T) and his compromised immune system/autoimmunity issues (due to PANDAS). Both issues scream to me that vaccines would not be advisable but he stated that neither condition are contraindicated for his upcoming 4 yr vaccines. Urgently looking to see if I can find any studies that might suggest otherwise to send to him. It sounds as though he may be open to testing his antibody titer levels to the vaccines to get an indication of his current level of protection. I plan on pushing for this to help guide the discussion but I’m not sure it will do much to resolve the disagreement. I’m in need of more supporting documentation from sources that he may respect, but I’ll take any research I can get.

Thank you,
Emily

March 11, 2012 at 6:23 am #1297

Lisa
I saw your post and had to respond. I do not have the studies on this topic. I was researching this very topic when I came across your post. But what struck me is that you feel you have to argue and plead your case in how you raise your child. This is YOUR child. The function of a pediatrician is not to stand over you, like a boss, and order you how to raise your child. These decisons are yours to make, not the doctor’s. If your doctor leaves you having to argue with him or her, then you should find a different doctor. Doctors like this will cross the line in many areas. They have God-complexes. You do not need someone who thinks they are your boss, being hired by you. You are the customer. YOU are paying the doctor, not the other way around. The doctor works for you, not the other way around. You are the one who is accountable for what happens to your child. If your child gets sick or ends up with permanent damage from these shots, you cannot run back to the doctor and expect him to be accountable. You are the one your child has to watch out for him, not your doctor. Don’t let some doctor push you around. Remember, YOU pay the doctor to work for you, not the other way around.

March 16, 2012 at 12:29 am #1346

Katie
We have the MTHFR and PANDAS. Our immunologist and our holistic medicine doc said NO VACCINES at least until we get the immune system rectified. You have NOTHING to lose by waiting. Our DAN doc said that vaccines today are not even vaccinating against diseases as they present today. In hindsight, I wish I had not given them in the past. The HINI flu vaccine is what sent my kids over the edge two years ago. I say proceed with caution……you can always add them in later but you won;t be able to undo it if they have a bad reaction. Of course, you know what the situation is better than anyone.

March 16, 2012 at 2:58 pm #1351

Beverly Hennager
You can change doctors. I was told by a person with an autistic son (that she was sure was caused from vaccinations) that you can order shots without the mercury, and space them far apart. But if it were me, I would not even chance that without expert opinion from someone like Ben. Trust your gut instincts.

________________________________________________

p.s. women who serve in the military are almost 3 times as likely to have a child with birth defects. I really noticed some of my health problems when I was in the military. Then again it might have been Coca Cola's fault, too.

We got like... God knows how many vaccines in one day at basic training?

Now I get to try to raise an autistic child while I have chronic fatigue @_@

And VA doesn't consider us "veterans" if we didn't go overseas at least 24 months.

But your health can end in one day.

Tesla_WTC_Solution
14th January 2014, 09:18
http://www.brainbalancecenters.com/2013/05/kids-with-autism-detect-movement/

Kids With Autism Detect Movement Twice As Fast As Other Kids
Home » Blog » Articles » Kids With Autism Detect Movement Twice As Fast As Other Kids

Kids with autism can detect simple movements twice as fast as kids who don’t have the disorder according to new research from the University of Vanderbilt and the University of Rochester. This information may help explain why people with autism are uncomfortable in certain environments, particularly crowded or bustling ones. A recent NPR article about the results of the study states the following:

“One can think of autism as a brain impairment, but another way to view autism is as a condition where the balance between different brain processes is impaired,” says Duje Tadin, a co-author of the study out this week in the Journal of Neuroscience. “That imbalance could lead to functional impairments, and it often does, but it can also result in enhancements.”
To read more about how researchers quantified this substantial movement perception difference in people with autism, click here. This study lends further support to Dr. Robert Melillo’s theory of Functional Disconnection as it applies to neuro-developmental disorders in children. A well functioning brain communicates between both hemispheres and within each hemisphere at lightning speed. These communications are like runners in a relay race: They connect, pass information, and release, repeating this process millions of times a minute. In a poorly functioning brain, these “runners” are often out of sync, missing each other or passing on only partial information. At Brain Balance, we call this miscommunication Functional Disconnection Syndrome, and our program works by improving or correcting this underlying communication issue.

Once we understand the uniqueness and severity of your child’s challenges through our Comprehensive Assessment, we then custom design physical, sensory-motor, and cognitive activity plans to establish proper neural connections and improve rhythm and timing. As brain communication improves, symptoms of learning and developmental disorders are reduced or eliminated. We also offer nutritional guidelines and dietary support for a whole-child approach to improving behavior and functioning. Our proprietary, non-medical program has helped thousands of kids reach their physical, social, behavioral, and academic potential. We work with children who exhibit symptoms of ADHD, Dyslexia, Tourette’s, Asperger’s, and Autism Spectrum Disorders. Contact us today to learn more!










http://www.omniintelligencer.com/Autism/Information/Processing-Speed-of-the-Brain.html

Tuesday, January 14, 2014
Home > Autism > Information > Processing Speed of the Brain

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Processing Speed of the Brain
Written by Paul Novak | PDF Print E-mail

There are dozens of research papers and anecdotal stories about the relationship between learning difficulties and brain processing speed. For example: the commercially available program Fast ForWord was developed in 1996 by a team of neuroscientists at the University of California to improve the reading levels of remedial students. The program exercises ran for one hour per day, five days per week for eight weeks – 40 hours of therapy training. At the end of the 40 hours all of the students were reading from 1 ½ to 2 grade level higher than when the started the program.

After purchasing a copy of the program (for $1,000) and trying to put my daughter through the exercises I quickly realized that this program was far beyond the comprehension of a 5 or 6 year old. The next thing that I discovered was that the exercises had nothing to do with teaching reading skills. There were no phonics exercises, word recognition exercises or comprehension training tests. All of the exercises involved focus, attention and processing speed of the brain. After 40 hours, just about everyone showed noticeable improvement in their reading speed and comprehension. As a side note some parents reported to the neuroscientists at the University of California that after completing the program their child had been cured of their dyslexia or their autistic child showed improved social skills.

When I asked one of these scientists “Why aren’t you marketing this program as a possible cure for dyslexia or autism?”, their response was “We don’t know why it works”.

My response to him was, “Mom doesn’t care why”. 14 years later and they still don’t know why it works.

The more convincing research was done at the University of Missouri where a researcher was able to predict with 92.5% accuracy which children as young as 2 years were autistic. His test was objective, passive and very simple. He placed the child in a darkened room, turned on a bright light and measured the time that it took for his pupils to constrict. (No explanation was given as to how long was too long) but his accuracy was impressive.) When you consider that the function of the pupils adjusting to changes in light levels is an involuntary reaction of the brain and can be considered a measure of its processing speed, the relationship and importance of brain processing speed cannot be ignored.

If computer games and exercises can improve reading skills, cure dyslexia and affect social behavior of autistic children simply by increasing the processing speed of the brain, then this therapy should be tailored for every age level and administered routinely.

When I could not find any “Brain Game” type programs that were suitable for a 4 year old, I decided that my only option was to develop my own program. I experimented with flash cards to determine what stimulus worked best. When I found that a picture of a dog or a cat was easily recognized every time, I moved to computerize my idea. I hired a computer programmer to develop the program to my design specifications. And after several hours of trial and error testing we finalized STIMBRAIN.

The program uses three similar but different exercises to measure the brain’s processing speed both in relation to reaction time and cognitive time. The fourth exercise is specifically designed to use focus and concentration to increase the processing speed of the brain by flashing images of a dog or cat onto the display at a steadily faster rate. The beauty of this program is that it records and displays the child’s performance for each exercise and the parent or teacher can easily see improvement in each area over time. Measurable results are critical to maintaining interest and enthusiasm.

STIMBRAIN is available at: www.YourChildsBrain.com at a modest price.

I use the example of going to a health club to build muscles. After many hours of strenuous muscle exercises, if a person does not see noticeable improvement in his body, he will quickly lose interest and eventually stop going to the club. However, the brain responds more quickly to stimulus and exercise. After as little as 40 hours of exercise you will see noticeable and measurable improvement. A small sacrifice to make for a lifetime of benefits.



http://www.npr.org/blogs/health/2013/05/09/182717089/kids-with-autism-quick-to-detect-motion

Kids With Autism Quick To Detect Motion
by LYDIA ZURAW
May 10, 201312:47 PM

Children with autism see simple movements twice as fast as other children their age, a new study finds.

Researchers at Vanderbilt University and the University of Rochester were looking to test a common theory about autism which holds that overwhelming sensory stimulation inhibits other brain functions. The researchers figured they could check that by studying how kids with autism process moving images.

"One can think of autism as a brain impairment, but another way to view autism is as a condition where the balance between different brain processes is impaired," says Duje Tadin, a co-author of the study out this week in the Journal of Neuroscience. "That imbalance could lead to functional impairments, and it often does, but it can also result in enhancements."

Jeff Hudale, who is autistic, demonstrates a face recognition test at the University of Pittsburgh in 2010. Researchers use eye tracking devices to monitor and record what he is looking at.
Shots - Health News
What's Different About The Brains Of People With Autism?
Tadin and his colleagues presented 46 children — 20 with autism and 26 without — with short video clips of moving black and white vertical bars. The images appeared in three different sizes and all the kids, ranging in age from 8 to 17, had to do was indicate whether the bars were moving right or left.

The scientists ran the experiment twice — once with high-contrast images and then again with low-contrast ones.

When the black bars were darker and easier to see, the researchers expected the autistic children to do better, figuring they'd be less inhibited by so-called spatial suppression, a mechanism that makes it harder for typical observers to perceive motion as the things they're looking at increase in size.

The autistic children did do a lot better with the higher contrast images than the control group, but not because they lacked spatial suppression, it turns out. As the image size increased, the autistic kids were slower at recognizing motion. But at each size, they were still twice as fast as the control kids.

Children with autism detect simple movement twice as quickly as their typically developing peers.
Children with autism detect simple movement twice as quickly as their typically developing peers.

Duje Tadin, University of Rochester
"That was really surprising," says Jennifer Foss-Feig, another study author. "People have not found this enhanced motion perception before."

Even though the researchers' original hypothesis didn't hold up, they think their findings still fit into the broader causation theory.

"The thought is that sensory systems develop very early on and if you have differences or deficits in terms of the way your brain is responding to sensory input, that would have real cascading effects developmentally," Foss-Feig says. "So there could be higher order cognitive and social and behavioral deficits."

http://media.npr.org/assets/img/2013/05/10/56301_web_custom-565ce37a6fb8c2b44c03e05df5652ee5562b78f4-s3-c85.jpg


http://www.psychologytoday.com/blog/extreme-fear/201003/how-the-brain-stops-time

http://www.huffingtonpost.com/2013/08/20/slow-down-time_n_3567218.html

Tesla_WTC_Solution
15th January 2014, 19:25
http://www.cnn.com/2014/01/15/health/fda-acetaminophen-dosage/index.html?hpt=hp_t2

FDA: Acetaminophen doses over 325 mg might lead to liver damage
By Holly Yan, CNN
updated 12:51 PM EST, Wed January 15, 2014

(CNN) -- You're in pain after surgery, and your doctor prescribes you Vicodin, or maybe Percocet. But when you get home, the pain hasn't subsided and you decide to pop some Extra Strength Tylenol.
Unknowingly, you may have just taken more of the drug acetaminophen than is safe.
Acetaminophen is often used in pain medications with opioids such as oxycodone (Percocet), hydrocodone (Vicodin) and codeine (Tylenol with Codeine). These are called combination drugs, and the Food and Drug Administration is asking doctors to stop prescribing those that have more than 325 mg of acetaminophen per dose.
The FDA says no data show that taking more than that amount provides enough benefit to outweigh the risk of liver damage.
"Many consumers are often unaware that many products (both prescription and OTC) contain acetaminophen, making it easy to accidentally take too much," the FDA said in a statement Tuesday.
The warning does not apply to over-the-counter drugs such as Tylenol, which contains acetaminophen. The FDA said it will address over-the-counter products in another regulatory action.
In 2011, the FDA asked manufacturers to limit the amount of acetaminophen in prescription combination drugs to 325 mg per capsule or tablet by January 2014. While more than half of the manufacturers agreed, some combination drugs with higher amounts of acetaminophen remain on the market.
The federal agency says it plans to start the process of withdrawing approval of prescription combination drugs from manufacturers that have not complied.
Health risks
"Acetaminophen overdose is one of the most common poisonings worldwide," according to the National Institutes of Health.
Taking too much of this pain reliever can lead to liver failure or death.
The FDA has set the recommended maximum for adults at 4,000 milligrams per day. It's easier to reach this limit than you might think; one gel tablet of Extra Strength Tylenol, for example, contains 500 mg.
New Tylenol cap will have warning label
Consumers should not take more than the prescribed dose of any medication that contains acetaminophen, according to the FDA, and should avoid taking more than one acetaminophen product at a time. Drinking alcohol while taking acetaminophen also puts you at risk.
To find out if your medications contain acetaminophen, read the drug label or the list of ingredients in the patient information leaflet that came with your prescription. Look for the word "acetaminophen" or the letters "APAP," an abbreviation sometimes used for the drug. If you are still unsure, contact your doctor or pharmacist.
Acetaminophen may also cause serious skin reactions in some people. According to the FDA, the skin reactions are rare but can be deadly. These conditions can cause blisters, serious rashes, reddening of the skin and the detachment of the upper surface of the skin, the epidermis.
Anyone who develops these types of conditions after using acetaminophen should stop taking the product immediately and visit a doctor or emergency room.
FDA issues warning about acetaminophen and skin reactions
CNN's Jacque Wilson, Saundra Young and Val Willingham contributed to this report.

_________________________________________________________

http://www.greatplainslaboratory.com/home/eng/Acetaminophen.asp

Evidence that Increased Acetaminophen use in Genetically Vulnerable Children Appears to be a Major Cause of the Epidemics of Autism, Attention Deficit with Hyperactivity, and Asthma

By William Shaw, Ph.D.

Tesla_WTC_Solution
17th January 2014, 19:56
http://newscenter.sdsu.edu/sdsu_newscenter/images/stories/autism-Illustration630b.jpg

Thursday, May 26, 2011
Overconnectivity in Brain Found in Autism
Findings from SDSU's Brain Development Imaging Laboratory differ from current brain connectivity theories.

http://newscenter.sdsu.edu/sdsu_newscenter/images/stories/autism-Illustration630b.jpg
Illustration of atypical connectivity patterns observed using functional connectivity MRI. See end of story for more information about the illustration.

By Golda Akhgarnia
Although it has been long known that autism is primarily a neurological disorder, the exact nature of brain disorders in autism is not well understood. Two recent studies from San Diego State’s Brain Development Imaging Laboratory suggest that current theories may be missing an important piece of the picture: overconnectivity in the brain.

Recent evidence has suggested that brain connectivity is affected in those with autism, and many studies have reported “functional underconnectivity,” meaning that regions in different parts of the brain talk less to each other. The underconnectivity theory, which was originally proposed in 2004, received broad attention and has been generally accepted until recently.

About the SDSU studies

However, in a study led by SDSU psychology Professor Ralph-Axel Müller (published in Cerebral Cortex), all existing studies of functional connectivity were surveyed and it was found that a growing number of studies actually show a very different pattern of results, suggesting that in autism, the brain may be partly overconnected.

This hypothesis was then tested in a second study from the same lab, led by Patricia Shih and published in Biological Psychiatry. It found that a brain region in the temporal lobe, which is important for several functions known to be impaired in autism (biological motion perception, language, auditory processing, auditory-visual integration), is more widely connected with other parts of the brain in children and adolescents with autism than in typically developing children.

This study is also the first to show that the specialization of cortex in this part of the brain is reduced in those with autism. Whereas in typically developing children, neighboring parts of cortex become increasingly specialized with age, this specialization was found to be impaired in children with autism.

Different perspective of autism

These findings create a picture of brain abnormalities that differs strongly from the “underconnectivity theory.” The data suggest that functional networks in the brain, which specialize in different functions (e.g., language or imitation), are not simply less well connected. Instead, cognitive and behavioral problems in autism may arise from the fact that these networks connect broadly with too many other parts of the brain and therefore do not specialize well.

The causes of these impairments are not understood at present, but they may relate to findings of early brain overgrowth in children with autism. Impaired “synaptic pruning,” which refers to the loss of connection between nerve cells that is important for brain organization and network specialization in typical development, may also play a role in overconnectivity observed in the study by Shih and colleagues.

More about the illustration at the top of the story

Illustration of atypical connectivity patterns observed using functional connectivity MRI. In the typical brain, a simplified example network shows strong connectivity (thick blue lines) between three brain regions (A, B, C).

These three regions are connected more weakly in ASD (thin red lines). However, the network also includes connections with other brain regions (D, E, F) that do not exist in the typical brain (dotted red lines).

Tesla_WTC_Solution
17th January 2014, 20:02
http://www.cosmosmagazine.com/news/boys-with-autism-have-a-bigger-brain/

Boys with autism have a bigger brain
Agence France-Presse
Abnormal brain growth starting at four months of age occurs in a type of autism in which toddlers lose language and social skills they once had, according to a new study.


http://cdn0.cosmosmagazine.com/wp-content/uploads/boys%20with%20autism.jpg
Boys with autism have a bigger brain than girls with autism, according to a new study. An earlier study has also found that autistic brains in general are about 18% heavier on average than the brains of non-affected people. Credit: University of California, San Diego - Autism Centre of Excellence



WASHINGTON: Abnormal brain growth starting at four months of age occurs in a type of autism in which toddlers lose language and social skills they once had, according to a new study.

The brains of boys with regressive autism grew 6% larger than typically developing counterparts and toddlers who showed signs of autism early in life, a form called early onset autism.

The research, involving 180 subjects and described as the “largest study of brain development in preschoolers with autism to date”, also found no evidence of a brain growth spurt in girls with autism.

“This adds to the growing evidence that there are multiple biological subtypes of autism, with different neurobiological underpinnings,” said co-author David Amaral, research director of the MIND Institute at University of California, Davis.

Abnormal growth for boys with autism

Autism includes a wide spectrum of developmental differences and may range from mild social awkwardness to complete inability to communicate, repetitive movements, sensitivity to certain lights and sounds, and behavioral problems.

As many as one in 110 children is diagnosed with autism, though its cause remains a mystery. The disorder is more common in boys than girls by a factor of four to one.

Previous studies have suggested that clinical signs of autism tend to coincide with a period of abnormal brain and head growth that becomes apparent between the ninth and 18th month of life.

Normal brain growth for girls with autism

However this study, published in the Proceedings of the National Academy of Sciences today, is the first to show a difference in brain size between toddler boys with regressive versus early onset autism.

“The finding that boys with regressive autism show a different form of neuropathology than boys with early onset autism is novel,” said lead author Christine Wu Nordahl, a researcher at the MIND Institute.

“Moreover, when we evaluated girls with autism separately from boys, we found that no girls – regardless of whether they had early onset or regressive autism – had abnormal brain growth.”

Loss of skills

The findings showed that boys with regressive autism had a “pronounced increase” in head circumference beginning as early as four months of age and lasting through 19 months.

The data was based on head circumference measurements taken from pediatric well-baby visits from birth through 18 months, and magnetic resonance imaging (MRI) scans done on all 180 participants at age three. The authors noted that the study was limited because it relied upon parental reports of when the children’s autism began to appear.

Previous research has “pointed out significant complexities in defining and measuring the onset of autism symptoms,” with as many as 45% of kids in one study showing signs of autism on video that were not reported by parents.

“The major finding of this study is that a subset of boys with regressive autism have normal head circumference at birth, which diverges from normality around four to six months of age, well before any loss of skills were documented,” said the study, calling for more research. “Thus, rapid head growth beginning around four-six months of age may be a risk factor for future loss of skills.”

More information:
Original paper in Proceedings of the National Academy of Sciences – open access
Christine Wu Nordahl’s homepage

Tesla_WTC_Solution
22nd January 2014, 03:19
Please check out these:

GOOGLE: "flu vaccine" "topoisomerase inhibitor"
Yields:
http://www.gsk.com/research/our-product-pipeline.html

http://www.gsk.com/etc/designs/gsk/_jcr_content/page/logo.img.png/1335964142535.png

Our product pipeline


Our medicines and vaccines in development are classified into three stages : Phase I, Phase II and Phase III. These studies into the safety and efficacy of investigational products provide data to support applications to regulators for approval. This page provides an outline of the medicines and vaccines in development.

The content of our development pipeline will change over time as new compounds progress from discovery to development and from development to the market. This annual pipeline information was published in March 2013. An update is expected to be available in March 2014.

Owing to the nature of the drug development, many compounds - especially those in early stages of investigation - may be terminated through the development process. For competitive reasons, new projects in pre-clinical development are not disclosed and some project types may not be identified.

Brand names appearing in italics are trademarks either owned by and/or licensed to GlaxoSmithKline or associated companies.


2140944 type 2 topoisomerase inhibitor bacterial infections Phase I


http://www.ageofautism.com/2013/09/dachel-media-review-imperfect-flu-shot-families-need-help-measles.html

Dachel Media Review: Imperfect Flu Shot, Families Need Help, Measles

Online news By Anne Dachel


The Daily Tar Heel (UNC)

"Scientists from UNC's School of Medicine have discovered a link between autism and environmental factors - and it all started over a longstanding lunch date."...

"Zylka said topotecan, a drug often used in chemotherapy, can be utilized to inhibit topoisomerase, an enzyme, which in turn limits the expression of certain genes.

"The genes limited by topotecan were particularly long, a characteristic shared by genes linked to autism.

"Zylka said the suppression of these genes by topotecan and other topoisomerase inhibitors, which may be present in the environment, could affect brain development in a manner that results in autism.

Flu shots in utero:

http://www.bidmc.org/YourHealth/Holistic-Health/Seasonal-Influenza-Vaccine.aspx?ChunkID=32652


DNA Topoisomerase Inhibitors
Common name: irinotecan (Camptosar)
This type of drug damages DNA during cell replication. Since cancer cells replicate faster than healthy cells, the effect is concentrated in tumor tissue. Irinotecan has shown promise in single agent treatment of esophageal cancer and in combinations.
- See more at: http://www.bidmc.org/YourHealth/Holistic-Health/Seasonal-Influenza-Vaccine.aspx?ChunkID=32652#sthash.pbsN5R2B.dpuf


http://www.thefreelibrary.com/AVAX+Technologies+Reports+1999+First+Quarter+Financial+Results.-a054642957

"During the quarter, AVAX also completed a $10 million private placement with firms such as Essex Woodlands Health Ventures Fund IV, L.P. and Petrus Fund L.P., an affiliate of Perot Investments. The net proceeds will be used primarily to fund pivotal trials of M-Vax, additional studies of O-Vax(TM), AVAX's autologous vaccine for ovarian cancer, studies in other cancers and Phase 1 clinical trials of our topoisomerase inhibitor and anti-estrogen technologies. In March, we also appointed James L. Currie of Essex Woodlands Health Ventures to our Board of Directors, and Arthur J. Atkinson, Jr., M.D. to our Scientific Advisory Board. Both individuals are strong additions who afford AVAX additional expertise in the financial and clinical research and development areas, respectively.

AVAX Technologies, Inc. specializes in the development and commercialization of novel biotechnologies, immunotherapies and pharmaceuticals for cancer and other life-threatening diseases using three core technologies: autologous cell (AC) vaccines, topoisomerase inhibitors and anti-estrogens.

http://en.wikipedia.org/wiki/Topoisomerase_inhibitor


Topoisomerase inhibitors are agents designed to interfere with the action of topoisomerase enzymes[1] (topoisomerase I and II), which are enzymes that control the changes in DNA structure[2] by catalyzing the breaking and rejoining of the phosphodiester backbone of DNA strands during the normal cell cycle.

In recent years, topoisomerases have become popular targets for cancer chemotherapy treatments. It is thought that topoisomerase inhibitors block the ligation step of the cell cycle, generating single and double stranded breaks that harm the integrity of the genome. Introduction of these breaks subsequently leads to apoptosis and cell death.

Topoisomerase inhibitors can also function as antibacterial agents.[3] Quinolones have this function.[4]

http://www.webmd.com/brain/news/20130826/fda-strengthens-fluoroquinolone-warning


Aug. 27, 2013 -- The FDA is strengthening its warning that a popular class of antibiotics, called fluoroquinolones, may cause sudden, serious, and potentially permanent nerve damage called peripheral neuropathy.

Fluoroquinolones are antibiotics that are commonly used to treat a variety of illnesses such as respiratory and urinary tract infections. These medicines include ciprofloxacin (Cipro), gemifloxacin (Factive), levofloxacin (Levaquin), moxifloxacin (Avelox), norfloxacin (Noroxin), and ofloxacin (Floxin). More than 23 million patients received a prescription for one of them in 2011.

Peripheral neuropathy is damage to the nerves that send information to and from the brain and spinal cord and the rest of the body. Damage interrupts this connection, and the symptoms depend on which nerves are affected. In general, the symptoms are in the arms and legs and include numbness, tingling, burning, or shooting pain.

Peripheral neuropathy has been listed as a side effect of fluoroquinolones since 2004. There have been reports of long-lasting nerve damage and disability in patients taking this type of medication.

A recent FDA review revealed that the existing warnings for fluoroquinolones were inadequate. The FDA's newest alert requires that all drug labels and medication guides for fluoroquinolones be updated to better emphasize the risk for serious and potentially irreversible peripheral neuropathy.

http://www.sigmaaldrich.com/analytical-chromatography/food-safety/adulterants-and-additives.html

http://www.nutraingredients-usa.com/Regulation/Antibiotic-tainted-enzymes-find-way-into-products-in-US-Canada-EU-and-Japan

dangerous inhibitors in the baby formula


THIS CONTENT IS COPYRIGHT PROTECTED
However, if you would like to share the information in this article, you may use the headline, summary and link below:
Antibiotic-tainted enzymes find way into products in US, Canada, EU and Japan
By Hank Schultz, 04-Nov-2013

Enzymes manufactured in India contaminated with an antibiotic have appeared in the US and Canadian markets after popping in Europe and Japan. The contamination could result in one of the biggest slews of product recalls in history.
http://www.nutraingredients-usa.com/Regulation/Antibiotic-tainted-enzymes-find-way-into-products-in-US-Canada-EU-and-Japan

Tesla_WTC_Solution
27th January 2014, 06:53
Well, having an ASD diagnosis myself (from a complete asshole doctor! lol sigh), I can tell you that I didn't mean we (autistic people) should be eradicated,
but rather, uh, that the side-effects of being so sensitive (chemically, aurally, visually, in terms of allergies, etc.) might be acknowledged and addressed by people such as those who promote pooey products like CFE lightbulbs, vaccines, i.e. every product a government tries to force the public to accept as the new normal.

In regards to "high functioning autism", a good reference is the character Charles Wallace in Madeleine L'Engle's books. He's an absolute genius, but has some issues eventually. :P

However, as long as there are those in our world who suffer greatly, like Temple Grandin (who was diagnosed with brain damage as a young child and recently had a very revealing functional MRI) and possibly my own son, who seems to have lots of occasional sensory deficits, there is a need for doctors to look closer.

These sensory limitations (and excesses) contribute to him getting hurt. An example would be grabbing a thorny tree because he didn't look closely, or walking into a white table edge in a room painted white. He has some "proprioportion" and "spatial" problems, and has trouble breaking away from tedious rotes. But lately, has been developing fast.

What used to be a child who walked into lamp-posts has evolved into a magnificent and talent climbing/running addict.
The young man has demonstrated in many ways his extraordinary connection with the physical and psychic worlds.

However, he still can't speak, at age 6, and gets so angry when he is not understood...
That is something that medicine MUST address, and soon, if these children are to be educated.

Why is it that some children grow without speech, whereas others on the spectrum are naturally gifted in the use of language?

Some scientists have found that certain genes are being copied, deleted, reversing, stacking, etc. in these children and NOT all autism is equally miserable!

It is rigid thinking that leads us to assume that there is no pathology to autism itself; there is no such thing as perfect. Only decent.

Tesla_WTC_Solution
27th January 2014, 22:49
Sorry I got emotional about this subject.
It's not my wish to cause you suffering, or to my son, either.
I am impressed by how much you know about these things and the politics of the world.
However, sometimes our knowledge itself can be a barrier against learning. ~"Nine-Toes the Argonian" :P

You're correct that I need to take a step back from this and try to be more accepting of the condition people call Autism.

-but-

I get a lot of emails from other parents who are going through Hell's own time, trying to manage their kids' needs.
It takes a lot of support for one of these children to thrive.

http://upload.wikimedia.org/wikipedia/commons/thumb/e/e1/Eiffel_Tower_01.jpg/385px-Eiffel_Tower_01.jpg

It's like looking at the Eiffel Tower; the impossibly wide foundation of support,
terminating in one tiny individual point, the person in need. Our society is not ready for what this really means.
They do not have the charity required to boost the next race toward the sky -- we live in a racist culture,
and we know in our hearts what that meant for our ancestors and "gods", when our species went to war against diversity...


Madeleine L'Engle, as a scientist, was aware of the mitochondrial problems that these talented children might have in our time.
She actually DID believe that they WERE beyond the shadow of a doubt the next step in human evolution.
She was very clear about this, that they had better memories, and shamanic qualities; the ability to transcend time itself in order to discover and experience.

Since I do retain a small belief in the External Divine Form, I try not to talk about evolution much. Because we are not the measure of perfection.
We are the observers of the Form. The good book calls us "clay", being shaped by time and the effort of the maker.
That concept also applies to evolution.

But what is evolution, without compassion?

Love, understanding, service -- those are the things that defy the gravity of the human condition.
They are the only things which at this point in history can help us evolve, or even survive.

There are probably 1,000,000 different discussions a person could have regarding "ASD" and still be covering something new each time.

Thank you for your interest and the reminder that different isn't necessarily wrong.

I do tend to believe in efficiency as a law of the universe, thanks to the German in me,
but at the same time, I believe that there are things that overcome the concept of time.

http://upload.wikimedia.org/wikipedia/en/thumb/3/38/Swiftlytiltingplanet.jpg/200px-Swiftlytiltingplanet.jpg

http://30.media.tumblr.com/tumblr_lt637ot0IC1qcuz26o1_500.jpg

P.S. What becomes of the person with extreme abilities, but no faith in himself?

Tesla_WTC_Solution
28th January 2014, 05:21
Did you guys read the study about "vertical transmission" of viruses such as SV-40, and other Polyomaviruses thought to contribute in part to ASDs because these viruses in certain combinations have been found in samples of post-mortem autistic brains?

:(

Vertical transmission occurs when the parents are exposed to a virus (such as a vaccine or food contaminant or recombineering product) and pass this virus straight to the child themselves, becoming the vector for infection regardless of precautions taken against infection of the infant via vaccines...

It becomes a never-ending process whereby virus after virus is introduced into the parents, who transmit it to the offspring, and millions of wealthy investors profit grossly from the vaccine INDUSTRY...

Also there was a study linking the ONSET of a severe mitochondrial disorder in an ASD child to the introduction of vaccines; it triggered a very bad "frameshift" mutation and could have outright killed her (in fact this has likely killed many more children than would have "died because of measles" or what have you).

The Polyomavirus paper was published in Rome, and the other one was USA, iirc.




You know what an iteration is, right?
A problem that becomes more complex over time, in a predictable manner -- but prediction does not ameliorate the end result of triggered mutations and expression of bad genes.
It simple shifts the blame.

Michael Crichton was pretty concerned about gene patenting and other immoral practices involving innocent people.
He ended up dead pretty fast.


http://www.ncbi.nlm.nih.gov/pubmed/20345322

http://en.wikipedia.org/wiki/Michael_crichton




http://www.ageofautism.com/2010/05/vaccine-may-trigger-early-start-of-infant-epilepsy-vaccine-apologist-shrugs-off-science.html

J Child Neurol. 2010 Jan;25(1):107-9. Epub 2009 May 11.

Severe neuropathy after diphtheria-tetanus-pertussis vaccination in a child carrying a novel frame-shift mutation in the small heat-shock protein 27 gene.
Mandich P, Grandis M, Varese A, Geroldi A, Acquaviva M, Ciotti P, Gulli R, Doria-Lamba L, Fabrizi GM, Giribaldi G, Pizzuti A, Schenone A, Bellone E.

Department of Neurosciences, Ophthalmology and Genetics-Section of Medical Genetics, University of Genova, Genova, Italy.

Abstract

Mutations in small heat-shock protein 27 and small heat-shock protein 22 genes were found in association with Charcot-Marie-Tooth disease type 2 and distal hereditary motor neuropathy. We searched for mutations in small heat-shock protein 27 gene in an Italian family with peripheral neuropathy and intrafamilial phenotypic variability. A novel heterozygous frame-shift mutation c.476_477delCT was found while point mutations in most genes associated with hereditary neuropathies were ruled out. In the proband, who showed a severe early onset peripheral neuropathy, an independent pathogenetic effect on the peripheral nervous system secondary to the tetanus toxoid injection may be supposed. This is the first truncating nonsense mutation in the small heat-shock protein 27 gene identified so far and the clinical, neurophysiologic, and neuropathological findings are discussed.

______________________________

I know these things because I care very much, and someone up there gave me just enough brains to store just enough info...

http://miztikmindz.files.wordpress.com/2011/02/the_wise_owl.jpg?w=497http://3.bp.blogspot.com/_HUb2ygrQR50/SDCv0P24y-I/AAAAAAAABXI/xcXVzxft7d4/s400/nerd-talk-vect.png

Frank V
28th January 2014, 07:01
Did you guys read the study about "vertical transmission" of viruses such as SV-40, and other Polyomaviruses thought to contribute in part to ASDs because these viruses in certain combinations have been found in samples of post-mortem autistic brains?

:(

[...]


I am aware of the study of vertical transmission, and it may very well be one of the mechanisms through which biological evolution occurs. After all, viruses - and mind you that not all viruses are pathological - are nature's way of transferring genetic material.



You know what an iteration is, right?


I have worked as a computer programmer and I still on occasion do a little bit of scripting, so the answer is "yes".



A problem that becomes more complex over time, in a predictable manner -- but prediction does not ameliorate the end result of triggered mutations and expression of bad genes.
It simple shifts the blame.


That's the part I am having difficulty with, i.e. the fact that in the event of autism, there is a need for putting a blame on something, with as a connotation that there evidently doesn't seem to be such a need on account of sociopathy, arrogance, narcissism, imperialism, militarism, and lots of other sociological phenomena.

I for one am quite happy with "my bad genes", and I don't need or want to "be cured" - thank you very much. And it would then be most comfortable even if other people were also to refrain from wanting to "cure me". Brave New World, anyone?



Michael Crichton was pretty concerned about gene patenting and other immoral practices involving innocent people.
He ended up dead pretty fast.


I have ethical problems with the concept of patenting in general, because patents were supposed to offer protection against abuse and have in the meantime - and rather quickly even - become a tool for abuse. As a Free/Libre & Open Source Software advocate, I am very happy that the EU does not recognize the concept of software patents, even though the USA does.

But that all said, I have an even bigger problem with the patenting of genetic material, just as I have a problem with eugenics and even with transhumanism. It is immoral in every possible way.

Tesla_WTC_Solution
28th January 2014, 22:06
I didn't mean to imply that our genes are bad!

They are delicate! :)

p.s. have you read about the 9-repeat allele? native pride!!

http://www.ncbi.nlm.nih.gov/pubmed/15872345
J Nucl Med. 2005 May;46(5):745-51.
Increased dopamine transporter availability associated with the 9-repeat allele of the SLC6A3 gene.
van Dyck CH, Malison RT, Jacobsen LK, Seibyl JP, Staley JK, Laruelle M, Baldwin RM, Innis RB, Gelernter J.


Some people call it schizophrenia, but after studying Carl Jung, i thought perhaps "shamanism" was a better label!!

http://realitysandwich.com/164260/dream_shaman_switzerland/
http://voices.yahoo.com/native-american-influences-dreaming-3627473.html?cat=37

Tesla_WTC_Solution
7th February 2014, 20:20
hey guys, please read this article, it says that "flu during pregnancy" and "birth stress" causes autism, along with a chloride imbalance of some kind.
since many of them have too much ammonia in their bodies later, what the heck ????

also, what about flu shots in pregnancy and how much stress those might put on the fetus????? because mine was effed up and I got one.

http://www.nbcnews.com/health/kids-health/autism-study-points-way-calming-troubled-brains-n23931

Autism Study Points Way to Calming Troubled Brains (bad headline imo)

Researchers looking for simple ways to treat autism say they may have explained why at least some cases occur: It all has to do with the stress babies undergo at birth.

They’re already testing a simple drug for treating kids with autism and say their findings may point to ways to treat the disorder earlier in life.

It’s all experimental, but the study, published in the journal Science, should inspire other researchers to take a closer look. “This is exciting stuff to people in the field, because it’s getting at a basic mechanism," says Andrew Zimmerman of the University of Massachusetts Medical School, who reviewed the study.

Yehezkel Ben-Ari of the Mediterranean Institute of Neurobiology in Marseille, France, and colleagues have been treating children with autism with a diuretic called bumetanide that reduces levels of chloride in cells. Diuretics lower blood pressure by making people urinate more, reducing fluid.

Ben-Ari has had mixed success in his trials in kids, and wanted to prove his theory that chloride was the key.

He worked with two rodent “models” of autism — they’re the closest things scientists have for replicating autism in a human. One has mutated genes linked with autism, and another develops autism when given valproate, an epilepsy drug blamed for causing autism in the children of mothers who take it while pregnant.

“We have shown that if we administer the diuretic to the mother for 24 hours before and during delivery, the offspring is … cured."
They looked at what was going on in the brains of the mouse and rat pups just before and after birth. Then they gave the mouse and rat moms bumetanide — and fewer of their newborns showed autistic-like behaviors.

It suggests that a reset button isn't working in the brains of newborns as they are delivered.

“We have proven the concept that in autism, indeed chloride is elevated and perhaps our diuretic acts in reducing that,” Ben-Ari told reporters on a conference call. “We have shown that if we administer the diuretic to the mother for 24 hours before and during delivery, the offspring is … cured."

Ben-Ari has founded a company that is looking to develop a drug that might be used to treat autism.

No one suggests giving any such drug to a pregnant woman and especially not to a newborn. Its safety would have to be tested. Plus, right now there’s no way of telling whether a pregnant woman’s unborn baby is going to develop autism. “It’s impossible in humans — that’s the problem,” Zimmerman says.

Autism is becoming more and more common among U.S. kids, and researchers don’t quite understand why. The latest survey by the Centers for Disease Control and Prevention shows 2 percent of U.S. children have been diagnosed with an autism spectrum disorder, which refers to a broad range of symptoms, from the relatively mild social awkwardness of Asperger’s syndrome to profound mental retardation, debilitating repetitive behaviors and an inability to communicate.

Genetics are a large factor — if one twin has autism the other twin is very likely to — but genes don’t explain it all. Better diagnosis doesn’t explain all of it, either, and many scientists are looking at what happens in pregnancy. Some studies suggest that infections such as influenza during pregnancy may play a role.

"It’s impossible in humans — that’s the problem.”
There’s no cure and no good treatment.

Zimmerman says the brain is overexcited in autism, and Ben-Ari says his study shows that chloride is responsible for at least some of this. The process of giving birth can re-set the over-excited neurons, and the new study in Science suggests that oxytocin, the so-called "love hormone" which is released during birth, may play a role in doing so.

The diuretic has similar effects, Ben-Ari says. He is currently treating kids aged 3 to 11 with it but thinks if autism could be diagnosed younger, and kids treated younger, it might be more useful.

“The possibility for perinatal treatment with an agent such as bumetanide is an enticing possibility for the prevention or early treatment of the disorder,” Ben-Ari’s team wrote in their report. “However, this would require an accurate way to determine whom to treat because symptoms of autism spectrum disorder often do not appear until the second year of life.”

The study suggests a way to do this, Zimmerman says. The blood and amniotic fluid of pregnant women could be tested for chloride levels, and the newborns followed to see if those that develop autism were exposed to more chloride in the womb.

First published February 6th 2014, 1:54 pm

______________________________________________________


red alert do NOT get that shot while pregnant, my fetus STOPPED MOVING after they gave me the shot, within weeks.
It was so effing scary, I thought my baby was dead in there.

Fairy Friend
12th February 2014, 10:45
I am surprised to see the discord here for this has shown me the way to the answers I need to start bringing my grandson back from autism. He was a normal baby and I saw him fade away. Words and language lost. No this is not right. Eye contact where it wasn't before. Words have come back. We had a setback with him going on antibiotics again however we are swinging around and he is more like every other child.

I have things to share. It is a spectrum disorder. Many answers are right which is why curing 1 child with a wheat-gluten free diet works for one and not another. Mercury may affect one person more than another. Another maybe reacting to a protein in the vaccine. Why detoxifying (like epsom salt baths) works for some not others. Allergies to nickle or copper. We had high cadmium in our local well and why this may have helped and his father a nickle allergy. GMO another and so on.

My mother was told my brother and I were brain damaged from paint. My brother has a BS in mechanical and electrical engineering. I consider myself a psychic genius. BS Biochemistry, 10 years with cytogenetics, graduate school human oncology. Usually I am telling people that everything they know is wrong. Here I find many in tuned souls and Tesla started this thread with research in mind.

Here I get to say your all right and I think Dr Natasha campbell-McBride has it mostly correct with her thoughts about antibiotics and their use over generations and the priming of the gut at birth and whether it has various good and bad microbes present. Everything connects.

Wiring in the brain being an adaptable organ will enhance other areas. Curing the child or adult does not change enhanced abilities yet does not fully always repair diminished areas. They have the control to choose what they develop like the rest of us. Or not to. Autism and schizophrenics.

Telepathy, manifesting, precognition, telekinetic abilities, intelligence.....do not go away. My grandson can manifest and use telepathy and he still prefers it but can speak if he desires. He will never be exactly like other normal children for none of us are. Look around even in twins none of us are alike. It is are difference that make us strong and that strength you advocate. But I see wrongs to fix.

The physical vehicle is not operating to its full potential. Kinda on a massive scale and they are here to show the way.

I am an advocate for running the tests to see what is exactly wrong and exactly fix it. Autism is increasing to alarming numbers in increasing areas. The signal to see the truths will show us many truths. You will hear the word cured a lot more in the future.

chocolate
12th February 2014, 18:52
Some more information from Dr. Mercola: http://search.mercola.com/search/pages/Results.aspx?k=autism

And two of the links only:
Hepatitis B Vaccine Triples the Risk of Autism in Infant Boys
http://articles.mercola.com/sites/articles/archive/2009/10/08/Hepatitis-B-Vaccine-Triples-the-Risk-of-Autism-in-Infant-Boys.aspx

New Warning About Everyday Poison Linked to Alzheimer's, ADHD, and Autism
http://articles.mercola.com/sites/articles/archive/2010/03/20/david-ayoub-interview-february-2010.aspx

Hervé
12th February 2014, 20:06
Worth a repeat/repost:


Going even beyond the buying into, and "agreeing" to, "their" PR peddling that there is such a thing as autism:


The hoax at the bottom of Autism and Alzheimer’s (http://jonrappoport.wordpress.com/2013/03/23/the-hoax-at-the-bottom-of-autism-and-alzheimers/)
by Jon Rappoport March 22, 2013
www.nomorefakenews.com (http://www.nomoredakenews.com/)

For the medical cartel, Autism and Alzheimer’s are big, big business. Profits are soaring.

These two conditions are promoted as specific diseases. That’s where all the trouble starts.

If you read the Alzheimer’s and Autism definitions, which are the criteria for diagnosis contained in the psychiatric Diagnostic and Statistical Manual (DSM), you find there are no physical tests of any kind.

No blood tests, no saliva tests, no urine tests, no genetic tests, no brain scans.

Instead, what you see are lists and menus of behaviors.

What does this mean?

First of all, it means researchers haven’t found the cause of these conditions. If they had, they would state it.

So how do you say you’ve located a specific disease if you don’t know the cause? Answer: you can’t.

Take four people who are 70 years old and are experiencing severe memory loss. You’re a researcher. You don’t know why these people have this problem. You can guess, you can talk about maybe-this or maybe-that, but you don’t know.

Therefore, you can’t say the cause of the memory loss in each case is the same. It might well be different for each person.

Should you make up a label like Alzheimer’s and slap it on all four people? Of course not. A single label means a single cause. Otherwise, why use the label?

But you don’t know the cause. No matter how many behavioral characteristics of memory loss you name, you don’t know the cause.

Therefore, you have no business applying a single label to those four people. That’s not science. It might be marketing for drugs, it might be a lot of things, it might be about obtaining grant monies, but it isn’t science.

Take four young children who have suddenly withdrawn from the world. Same principle applies. If you slap them with the Autism label, you’re lying. You don’t know the cause of that withdrawal in any of the children.

Now, if you were the parent of one of these children, and you noticed that soon after the child was stuck with multiple vaccines, he developed a fever and then he withdrew from the world, you would, indeed, know something vital.

But if you’re an unbiased researcher a thousand miles away from these four children, all you know, at the outset, is that they all withdrew.

In two cases, the cause might have been vaccination. In another case, it might have been severe and chronic malnutrition or a reaction to heavy metals in food. In another case, the child might have developed a brain lesion. There are a number of possibilities.

Why then slap all four children with the label Autism?

Just because they exhibit the same general characteristic? That’s patently ridiculous.

Let’s take this a step farther. Suppose you had a group of 500 children, all of whom withdrew and folded up after receiving a load of vaccine. You know these vaccines contain toxins. You know the toxins were injected. You know the toxins can cause neurological damage.

Well, what are you waiting for? These are cases of VACCINE DAMAGE. It’s not Autism caused by vaccine damage. It’s not Autism or Cd3syt or Vcti45 or any other arbitrary label. It’s not a disease or a disorder. It’s poisoning. Do you say a person who develops a severe and chronic problem after eating fish loaded with poison has a disease? Is it the fish-eating disease?

Of course, we know that exonerating vaccines keeps a giant industry from destruction. And we know that putting a disease label on people opens the door to enormous profits. Drug-company profits. “Well, we’re researching several promising medicines for Autism…”

You don’t hear, “We’re investigating remedies for vaccine poisoning and exposure to industrial pollutants.”

Alzheimer’s researchers are very fond of talking about “biomarkers” and “imaging.” They keep testing blood and the spinal fluid. But they don’t know enough to include the results of those tests in the official definition of Alzheimer’s.

And think about this: suppose one biomarker finally emerges as a common denominator in a study examining 5000 people who have been diagnosed with Alzheimer’s? Who is to say the cause of that biomarker is the same in all 5000 people? This is not a trivial point. It’s crucial.

If, for example, chemicals can cause genetic changes, and then cancer researchers hail “new genetic findings in investigating the cause of cancer,” at what level are they plugging into the true situation? If they keep ignoring the chemicals, how far are they going to get?

Researchers and the press keep promoting a fairy tale: “If we diagnose people who show the same behavioral factors with a single disease label, and if we keep examining these people for common biomarkers, we’ll find the cause of the disease.”

Well, look at the DSM. It contains 297 official disorders, all labeled. Many of these so-called disorders have been investigated for decades. And yet, not one disorder lists a specific across-the-board diagnostic test that can define it.

Taking all this to a conclusion, we have this: there is no reason to suppose that Alzheimer’s or Autism exists.

Damage exists. And there are cogent reasons to infer that, in different individuals, the causes are different.

Therefore, what we need are very capable and independent-minded health practitioners who can investigate one patient at a time and find out what really caused his/her problem.

That is why, when somebody tells me he’s found the cause of Alzheimer’s or Autism, and the cure, I know he’s on the wrong track. He failed to notice that these conditions don’t exist. Damage exists.

In the alternative field, I’ve read journal articles that begin: “New discovery may revolutionize the treatment of Alzheimer’s…”

The author of the article was bamboozled. He accepted the idea that Alzheimer’s was a single disease. His opening sentence should have read: “New discovery may revolutionize the treatment of that thing that doesn’t exist…”

Then he and everybody else would see the error.

Damage exists. Memory loss exists. Withdrawing from the world exists. Suffering exists. Pain exists. Finding what caused it in a single patient, one at a time, is a step toward healing.

And healing is what it’s supposed to be all about.

The correct metaphor here is the detective. Suppose he says, “Well, we have a murder, and we know that murder is caused by bullets. So we’ll find the bullets and that will constitute the solution to the case.”

The detective investigates each case on its own facts and merits. He brings a wealth of experience to his work. He knows patterns in murders. He knows what sometimes turns out to be the answer. He applies what he knows. He uses clues. He uses logic. He tries one avenue, and if it doesn’t pan out, he embarks on another avenue. He keeps looking. He provisionally uses generalities, but he also avoids them. This is called intelligence. It’s called discernment. It’s called caring about finding the truth.

If genuine healing were the objective, practitioners would approach so-called Alzheimer’s and Autism patients very differently.

The fact that most medical doctors don’t is, at the very least, criminal negligence.

Back in the 1990′s, I interviewed the mother of a boy who had been diagnosed with Autism. He wasn’t a case of vaccine damage, because he’d never been vaccinated.

His health practitioner, during an extensive conversation with the mother, did discover a forgotten head injury at the age of three. The boy was now 16.

The practitioner tried a course of hyperbaric oxygen treatments, based on the hypothesis that some brain cells were in an “idling state,” and had never awakened after the injury. The treatments helped somewhat. The boy became a bit more communicative.

The practitioner then shifted the boy’s diet several times, and in the process found out he was having a severe and chronic reaction to milk and other dairy products. So they were eliminated from the diet. After a month, the boy came a bit more out of his shell. His awkward physical movements lessened.

Supplementation with minerals produced further results. The boy’s speech cleared up gradually. He mumbled less. His spoke more forcefully.

At this point, for the first time, the boy was willing to undertake a light exercise program. After a month or so, it produced dividends. His muscle tone improved, and he enjoyed short runs. He’d return from these runs with fierce enthusiasm. He was happy that his coordination was increasing.

Several new supplement protocols were tried. One of them included a meal-replacement drink that he liked. He came further out of his shell. His mother began home schooling him. His writing was no longer a dense scribble. He could focus on his work.

The boy went through another series of hyperbaric oxygen treatments. This time the results were more visible. His face, which tended to be mask-like, relaxed. He became more animated.

The supplement regime was enhanced with a ginseng adaptogen and a different type of magnesium. The boy received several adjustments from a chiropractor, who had been trained in the original techniques of the art.

A month later, the boy’s communication with his parents and his neighbors reached a new level. He had recovered a significant part of his life.

I asked the practitioner whether he would apply that entire course of treatment across the board for all children diagnosed with Autism.

“Absolutely not,” he said. “I don’t do ‘across-the-board’ anything.”

When I told a doctor what happened to this boy, he said, “It wasn’t Autism to begin with. He was misdiagnosed. It was a head injury.”

“No,” I said. “Nothing is Autism.”

He stared at me and then he smiled. “I know where you’re going with this,” he said.

“So?”

“Yeah,” he said. “They don’t have a cause for Autism.”

“So they have no right to say it’s a disease with a single cause.”

He scratched his head and walked away.

There is yet another reason the medical cartel wants to maintain this fiction about Autism and Alzheimer’s. It’s about controlling the research, of course. Keeping a lid on the fact that chemicals and inserted genes in the food supply; water contaminated with chemicals, including fluorides; heavy-metal particles sprayed in the skies; radiation; vaccines; medical drugs; industrial pollution and dumping; and other factors have been producing the symptoms of what is being called Autism and Alzheimer’s.

Covering all that up is a major priority. One dirty hand washes another.

Sources: “Dementia of the Alzheimer’s Type Symptoms and Diagnosis,” psychtreatment.com; “DSM-IV Criteria Pervasive Developmental Disorders,” firstsigns.org.

Jon Rappoport

PS: this all fall under the rubrique of "Propaganda" and "Psyops," see this post (http://projectavalon.net/forum4/showthread.php?54217-Their-Mind-and-the-Emotional-Matrix-that-we-create-with-it.&p=652209&viewfull=1#post652209) <---

Bob
12th February 2014, 21:29
I went to the OP, post #1, and Tesla said it clearly the whole track of events, and her intention for this thread. It was clear she wanted a SAFE SPACE for people to post research reports that are found on the subject. thank you TESLA for starting this wonderful thread as a repository for RESEARCH (with cited references). Bob

the OP:


Hello Avalon,
I wanted to make a safe place where anyone who wants to share an autism research link can post that, and of course, discuss the papers posted.

Since there are so many possible underlying factors being investigated, threads about autism often get derailed as people talk about more familiar assumptions and theories, and of course, the vaccination debate tends to darken some of those discussions for people who are unfamiliar with the more recent body of research in regards to de novo mutations and lack of evidence regarding whether autism is heritable.

There was a paper in particular that I want you guys to read if and when you have time.

The reason I want to talk about this here is that I trust most of you not only to leave this material safely here, but also to:engage and to care about this issue, as people with autism and mental retardation often suffer a lot of discrimination when their families seek benefits from the state or federal gov'ts.


:focus:

I would like to see the lists of pertinent and relevant research reports and papers that the thread title and what Tesla has asked for, AUTISM, focus.

I will ask Tesla to restart this thread when she gets back to re-correlate the research papers. I for one am working on a research project with a large group who are interested in compassionate solutions to identify, categorize, see what methods have worked, and then come up with support systems for families and their affected loved ones. A SAFE SPACE in other words.

jagman
13th February 2014, 04:37
I hope you come back soon Tesla. I think your full of passion and your threads
are extemely well written.You always provide links and pictures.

If i were grading you, I would give you a A-. I know youir saying... why the minus?lol
Bill has even stated that he likes you and he thinks your talented.

Chanlo23
13th February 2014, 18:32
http://newscenter.sdsu.edu/sdsu_newscenter/images/stories/autism-Illustration630b.jpg .... Although it has been long known that autism is primarily a neurological disorder, the exact nature of brain disorders in autism is not well understood. Two recent studies from San Diego State’s Brain Development Imaging Laboratory suggest that current theories may be missing an important piece of the picture: overconnectivity in the brain.

I believe Sensory Overload IS related to Autism. THIS thread is VERY relevant. It SHOULD definitely be kept ACTIVE! Sensory overload, I believe, can be exacerbated when Autism is present.

Recently, a number of studies have been done showing connections between Autism and Synthesia (also related to sensory overload):


http://www.sciencedaily.com/releases/2013/11/131119193908.htm. Summary: "Synaesthesia involves people experiencing a 'mixing of the senses', for example, seeing colours when they hear sounds, or reporting that musical notes evoke different tastes. Autism is diagnosed when a person struggles with social relationships and communication, and shows unusually narrow interests and resistance to change. The team of scientists from Cambridge University found that whereas synaesthesia only occurred in 7.2% of typical individuals, it occurred in 18.9% of people with autism. On the face of it, this is an unlikely result, as autism and synaesthesia seem as if they should not share anything. But at the level of the brain, synaesthesia involves atypical connections between brain areas that are not usually wired together (so that a sensation in one channel automatically triggers a perception in another). Autism has also been postulated to involve over-connectivity of neurons (so that the person over-focuses on small details but struggles to keep track of the big picture). The scientists tested -- and confirmed -- the prediction that if both autism and synaesthesia involve neural over-connectivity, then synaesthesia might be disproportionately common in autism.
http://blogs.scientificamerican.com/mind-guest-blog/2013/12/04/can-synesthesia-in-autism-lead-to-savantism/ Introduction[/B][/COLOR]: Daniel Tammet has memorized Pi to the 22,514th digit. He speaks ten different languages, including one of his own invention, and he can multiply enormous sums in his head within a matter of seconds. However, he is unable to hold down a standard 9-to-5 job, in part due to his obsessive adherence to ritual, down to the precise times he has his tea every day. Daniel is a savant. He is also autistic. And he is a synesthete. Daniel experiences numbers as having color, as well as shape and texture. This helps him perform amazing mathematical feats seemingly without effort, the answer simply materializing to him rather than having to calculate it out.
http://www.molecularautism.com/content/4/1/40 Background: Synaesthesia is a neurodevelopmental condition in which a sensation in one modality triggers a perception in a second modality. Autism (shorthand for Autism Spectrum Conditions) is a neurodevelopmental condition involving social-communication disability alongside resistance to change and unusually narrow interests or activities. Whilst on the surface they appear distinct, they have been suggested to share common atypical neural connectivity. Results: The rate of synaesthesia in adults with autism was 18.9% (31 out of 164), almost three times greater than in controls (7.22%, 7 out of 97, P <0.05). ToG-R proved unsuitable for synaesthetes with autism.
Conclusions: The significant increase in synaesthesia prevalence in autism suggests that the two conditions may share some common underlying mechanisms. Future research is needed to develop more feasible validation methods of synaesthesia in autism.
http://www.cam.ac.uk/research/news/synaesthesia-is-more-common-in-autism Summary:Donielle Johnson, a Cambridge Gates Scholar who carried out the study as part of her Master’s degree, said: “People with autism report high levels of sensory hyper-sensitivity. This new study goes one step further in identifying synaesthesia as a sensory issue that has been overlooked in this population. This has major implications for educators and clinicians designing autism-friendly learning environments.” - See more at: http://www.cam.ac.uk/research/news/synaesthesia-is-more-common-in-autism#sthash.z9TmgkLe.dpuf
http://www.bbc.co.uk/news/health-24995232 Introduction: Research suggests synaesthesia is nearly three times as common in adults with autism spectrum disorder than in the general population. The two conditions may share common features such as unusual wiring of the brain, say UK scientists. The study helps understanding of how people with autism experience life, says the National Autistic Society.

Bill Ryan
14th February 2014, 15:17
I went to the OP, post #1, and Tesla said it clearly the whole track of events, and her intention for this thread. It was clear she wanted a SAFE SPACE for people to post research reports that are found on the subject. thank you TESLA for starting this wonderful thread as a repository for RESEARCH (with cited references). Bob

Amen to that. I fully support Tesla in her clear and sincere intentions for this thread. So should we all.




Anyway - no offense intended

I have to say, I find that a little hard to believe.

:focus:

sheme
14th February 2014, 15:40
I thank you for this observation Bill, the By for now thread was closed before I could give my support to Tesla I do so here and now.

chocolate
15th February 2014, 10:14
The good thing about all that happened is that it gave me the opportunity to 'see' a lot of people for who they actually are.

As with everything it comes to a balance between who is more important.
I had time to learn to know a lot of people, to adapt to the "ways here", and also to find the time to feel totally out of place. It was all well done, and I am actually thankful for the opportunity.

A few will always remain my friends.

Now, I guess, I have to post

back to topic.

Bob
16th February 2014, 20:48
Hi Tesla - reading this today on neural toxicity in-utero and after birth for children..

"The developing human brain is incredibly vulnerable to chemical exposures, both in utero and in early childhood, and these changes can be lifelong. “During these sensitive life stages,” say the authors, “chemicals can cause permanent brain injury at low levels of exposure that would have little or no adverse effect in an adult.”

"The neurotoxin “pandemic” is disturbing enough that the authors strongly recommend having mandatory tests for chemicals, which many have been arguing for years.

"One common complaint has been that when one compound does finally become banned, another equally toxic and often untested chemical may take its place.

"More rigorous testing, though complicated to carry out, might address this major issue."

11 Toxic Chemicals Affecting Brain Development In Children

"The list of chemicals that can affect brain development in children has grown. In a study out today in The Lancet Neurology (http://www.thelancet.com/journals/laneur/issue/current), researchers outline new chemicals that may be contributing to what they dub the “global, silent pandemic of neurodevelopmental toxicity.”

These would be lead, methylmercury, polychlorinated biphenyls, arsenic, and toluene. Since 2006, epidemiological studies have documented six additional developmental neurotoxicants—manganese, fluoride, chlorpyrifos, dichlorodiphenyltrichloroethane, tetrachloroethylene, and the polybrominated diphenyl ethers.

Forbes covered the Lancet article here: http://www.forbes.com/sites/alicegwalton/2014/02/15/11-toxic-chemicals-afffecting-brain-development-in-children/

Contributors:
Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA
Icahn School of Medicine at Mount Sinai, New York, NY, USA

Some Highlights:

Tetrachloroethylene (AKAperchlorethylene)– These solvents have been linked to hyperactivity and aggressive behavior, and increased risk of psychiatric diagnosis. Mothers in certain professional roles, like nurse, chemist, cleaner, hairdresser, and beautician had higher levels of exposure. (this substance was used in the Lockheed Martin plant west of Highlands Ranch, Colorado, there was suspicion that this chemical leaked into the water supply over the years the plant was in operation, and lead to brain damage in the children. There were numerous shootings in the area, starting with Columbine Massacre to events less than two months ago.)

Arsenic – When absorbed through drinking water, this chemical has been linked to reduced cognitive function in schoolchildren. Follow-up studies from the Morinaga milk poisoning incident have linked it to neurological disease in adulthood.

Toluene – Used as a solvent, maternal exposure has been linked to brain development problems and attention deficit in the child, according to the EPA and OSHA. Toluene also was used as a cleaning agent in the Lockheed Martin plant, west of Highlands Ranch, Colorado.

ED NOTE: in this FORUM LINK (see post #4) we talked about the chemical leak coverup in the Lockheed Martin plant, a water researcher being snow-balled.. kids having grown up "downstream" from the plant drinking contaminated water, their Mom's having also..

http://projectavalon.net/forum4/showthread.php?67686-Columbine-Area-Schools--Colorado--currently-on-LockOut-Status

Bob
16th February 2014, 21:05
Hi Tesla, some more reports on toxins creating brain abnormalities..

the reference is: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404655/ - from Environ Health Perspect. 2012 July; 120(7): a258–a260.
Published online 2012 July 2. doi: 10.1289/ehp.1104285
PMCID: PMC3404655

Summary: Autism, attention deficit/hyperactivity disorder (ADHD), mental retardation, dyslexia, and other biologically based disorders of brain development affect between 400,000 and 600,000 of the 4 million children born in the United States each year. The Centers for Disease Control and Prevention (CDC) has reported that autism spectrum disorder (ASD) now affects 1.13% (1 of 88) of American children (CDC 2012) and ADHD affects 14% (CDC 2005; Pastor and Reuben 2008).

"Exploration of the environmental causes of autism and other NDDs has been catalyzed by growing recognition of the exquisite sensitivity of the developing human brain to toxic chemicals (Grandjean and Landrigan 2006). This susceptibility is greatest during unique “windows of vulnerability” that open only in embryonic and fetal life and have no later counter-part (Miodovnik 2011)."

Something that may be worthy of doing some studies on (to determine if chemical toxicity or viral damage occurred) may be obtained by questionnaire looking at these items:

1) Were there early exposures to medications taken in the first trimester of pregnancy—thalidomide, misoprostol, and valproic acid—and to first-trimester rubella infection (Arndt et al. 2005; Daniels 2006).

2) Were there early exposures to exposures to the organophosphate insecticide chlorpyrifos (Eskenazi et al. 2007) - malathion, used around the world to attempt to eradicate mosquitoes - used "on-base". Chlorpyrifos, an organophosphate insecticide, is the most widely used insecticide in the U.S. It is used both in agriculture and for pest control in houses and other buildings. Americans are widely exposed to chlorpyrifos. Typical diets, particularly those of children, contain significant chlorpyrifos residues. About 10 percent of the food items tested by the U.S. Food and Drug Administration contained chlorpyrifos residues, and illegal residues occur on many foods.

Diazinon is an organophosphate insecticide with agricultural, commercial, and household uses. Household uses predominate, with 75 million applications in the U.S. annually totaling over 5 million pounds.

Naled is an insecticide in the organophosphate pesticide family used primarily for mosquito control. Dibrom is a common brand name for Naled products. About one million pounds are used annually in the U.S. )

3) Were there prenatal exposures to phthalates (Miodovnik et al. 2011). (Phthalates have been used as plasticisers in many plastics since the 1930's. Hot plastics with food on them, beverages, can leech these substances into the food or beverage.)

4) Were there exposures to lead (Jusko et al. 2008), (lead existed in paints AND gasoline in the 40's through the 70's)

5) Were there exposures to methyl-mercury (Oken et al. 2008), (People in the U.S. and elsewhere are mainly exposed to methylmercury, an organic compound, when they eat fish and shellfish that contain methylmercury. Whether an exposure to the various forms of mercury will harm a person's health depends on a number of factors. Almost all people have at least trace amounts of methylmercury in their tissues.)

6) Were there exposures to organophosphate insecticides (London et al. 2012), organo-chlorine insecticides (Eskenazi et al. 2008), (these chemicals are/were used frequently to treat for ANTS around houses, to spray outdoor plants)

7) Were there exposures to polychlorinated biphenyls (Winneke 2011), (these are insulating oils typically found in transformers, banned by 1979, and potentially dumped into landfills and having made their way into the water. The St. Lawrence Seaway has notorious sediments of such chemicals, and others - larger fish and whales have been declared "TOXIC" from having consumed bottom fish in the Seaway)

8) Were there exposures to arsenic (Wasserman et al. 2007), (arsenic is used as a WOOD PRESERVATIVE, typically a green colored preservative)

9) Were there exposures to excessive manganese (Khan et al. 2011), (Manganese can exist in water wells, as well as living near steel mills, with manganese emission in the air)

10) Were there exposures to polycyclic aromatic hydrocarbons (Perera et al. 2009), (these items can be found in spray paints, even from forest fires or emissions from volcanoes)

11) Were there exposures to bisphenol A (Braun et al. 2011), (plastic bottles used in drinking, used in baby bottles, used to coat cans insides to prevent them from rusting)

12) Were there exposures to brominated flame retardants (Herbstman et al. 2010), (these items can exist in RUGS, in couches, stain resistant and fireproofed lounge chairs, in short anywhere a consumer grade cloth has been treated to reduce its flammability rating)

13) And lastly, were there exposures to perfluorinated compounds (Stein and Savitz 2011). For instance many popcorn bags are coated on the INSIDE with PFC's to make them stick resistant. Placing such in the microwave, heating and eating exposes one to the PFC's. Did Mom have such types of popcorn while baby was in utero?) ref: http://watoxics.org/chemicals-of-concern/perfluorinated-compounds-pfcs

Doing such an inventory questionnaire may therefore help a Mom understand what happened, and possibly prevent future exposure to more babies in utero. A report created by a researcher could offer this type of data, showing statistically the potential for damage, and possible environmental factors can be changed. Alerting new Moms to such substances, I think is very important.

I suspect based on the prevalence of both LEAD from gasoline vapors, and the Organo Phosphate insecticides, that the amount damage of neo-natal, in-utero, and in young children could be traced back to those influences, secondarily, the tri and tetra-chloro-ethylene "cleaning" compounds. The TCE's were used frequently "on-base" to address the stains on airplanes, on the flight lines. They were used in dry cleaning facilities, and would evaporate into the environment - noteworthy uses for removing of grease stains.

I was privy in about 2000-2001 to solvent ground seepage problems in Eglin AFB, Florida. I was asked if there was a cleanup solution to that underground seepage problem. At the time there was no solution evident, the solvent was continuing to move underground.

Bases known to be contaminated: http://www.gmasw.com/ao_bases.htm (old study, 1992)

A more recent study - http://www.atsdr.cdc.gov/HAC/pha/PHA.asp?docid=173&pg=1

"ATSDR investigated a contaminated groundwater plume originating from the C-6 Radar Facility.The nearest down-gradient drinking water wells from this site are located off base, 3 miles south,in the town of Portland, Florida. The extent of the trichloroethylene (TCE) contamination was defined to be entirely on Eglin AFB property. To ensure that the contamination does not migrate to Portland, the Air Force conducts long-term monitoring of the groundwater at the site on an annual basis (Earth Tech 2000a)." They are aware and "monitoring"..

Bob
16th February 2014, 22:07
Fetal brain abnormality, potentially in Autism, ADHD, ADD, hyperactivity disorder

from reference - http://www.addictiontreatmentmagazine.com/addiction/drug-abuse/inhalant-use-during-pregnancy-cause-of-brain-damage/

Inhalant use, or accidental exposure from working with solvents, paints (especially aerosol paints), or deliberate exposure has been creating brain damage in babies in the womb.

"Like alcohol and classic drugs of abuse that produce harmful changes in pregnancy—such as cocaine, amphetamine, methamphetamine, and heroin—inhalants achieve their negative pregnancy-related effects because they can pass through a blood vessel network called the placental barrier, which indirectly connects the blood supply of an expectant mother and the blood supply of her developing fetus inside the placenta. In order to survive, a fetus relies on this barrier for the transfer of oxygen and nutrients from the maternal bloodstream; it also relies on the placental barrier to pass carbon dioxide and other types of waste to the maternal bloodstream for eventual elimination."

"Inside an expectant mother’s bloodstream, inhalants called volatile solvents can significantly reduce the amount of oxygen available for transfer to a developing fetus, the Royal Women’s Hospital reports. In turn, reduced oxygen flow to the fetus can potentially produce oxygen deficits that alter or delay the development of the brain skills that people rely on from birth for such basic tasks as learning, using memory, and exercising higher-level judgment and decision-making abilities. In some cases, these delays may be temporary; in other cases, they may remain as permanent mental impairments. Inhalants classified as volatile solvents include paint thinner, paint remover, gasoline, degreasers, and various types of dry-cleaning fluid."

If you can smell it, and you are pregnant, you could be exposing your baby to these substances. Earlier posts have shown studies where definitive brain damage has happened.

Besides toluene, specific chemicals in volatile solvents that can trigger the onset of fetal solvent syndrome include benzene, petroleum ether, xylene, and methanol; all of these chemicals are frequently found in substances preferred by inhalant users. All these chemicals are used industrially, and commercially. Exposure can be deliberate (huffing), or accidental, being around a facility which uses these substances in its daily operations.

Since many of the chemicals capable of producing fetal solvent syndrome appear in gasoline, doctors also sometimes refer to the condition as fetal gasoline syndrome. Are those vapors being inhaled while pumping gasoline? If you smell it, it is possible such is happening.

Among all inhalants, toluene is particularly well-known for its ability to damage fetal or newborn health when used during pregnancy. Toluene is found in most paints which say they adhere to PLASTICS very well. In Australia, Toluene has been illegally found combined with GASOLINE. ref on Toluene: https://www.osha.gov/Publications/OSHA3646.html - Toluene is used in many products and workplaces, from printing operations, manufacturing facilities and construction sites even to nail salons.

Is your nail polish TOXIC? see http://kimberlysnyder.net/blog/2012/11/03/is-your-nail-polish-toxic/ - check that site and notice the comments on the pthalates and toluene (toluol)

Apart from fetal solvent syndrome, specific potential impacts of the chemical include chromosome alteration or outright chromosome damage, increased risks for a miscarriage or stillbirth, and an increased risk for withdrawal symptoms in a child born to an inhalant user.

pugwash84
17th February 2014, 15:40
Both my boys are on the ASD spectrum and the doctor is now testing them for fragile X syndrome which is what she is thinking they have. It effects boys more than girls and my girls are fine just the boys on the spectrum. One of my boys is severely autistic the other is more like Asperger's .

http://en.wikipedia.org/wiki/Fragile_X_syndrome

http://www.autism.org.uk/about-autism/related-conditions/fragile-x-syndrome.aspx

Flash
17th February 2014, 15:46
there are many needs when talking of autism Spectrum:

1. The cruel need for information, for parents, families and autistic people. Information is lacking, research if not what it should be. It is getting better (10 years ago you would scratch your head) but it is not entirely there yet. The need for information is sooooo great that it must be made available to all. If we do not get the information we can, how can we decide on paths to follow (treatments, prayers, nothing to do, etc).

2. The needs of next of kin: Parents are desperate for information and understanding. Until you have seen a grown up 40 years old men his head on your table with unstopable tears crying, for his beloved son, you haven't seen the overall of the autism Spectrum. It does not stop at the autistics themselves. Borthers and sisters are also impacted, sometimes correctly but most of the time badly, depending on the depth of the symptoms of the autistic brother/sister. These needs here are informational, emotional and Financial. Often one of both parents have to give up their job for their child and poverty follows. Other times they pay for alternative treatments that are more or less efficients, depending on the "unknown" source of the behavioral/mental differencers, but nevertheless very expensive. Poverty follows.

3. The needs of the autistic person: Living with autism can be at times very difficult. In fact, in my views, so difficult at times that it is almost at par with torture. Deep autistic people are often deprived of their families at a later age, and are put into homes that are not the best for anyone, if the state does grant this. With higher autism, although very responsible human beings, they will often have problems to find a well paid job, once on the job they may be discriminated, not understood for sure, name it. Same at school. Until you have seen a Young boy getting in your home after school having a melt down, only to discover later after the melt down and hours to make him talk, that he had been treathened to be killed by 2 boys in the school bus, until then, you cannot understands what they go through on a daily basis. And here melt down means kicking, crying, screaming, pitching himself eveywhere, then kicking on the floor, at 5 foot 2 and 140 pounds 10 years old. They need comprehension, protection, help, introduction in the world, and mostly, patienly listening to their individual needs. And be able to express them and live their life to their best.

4. The need for understanding the greater implications of autism, being at times the need for some geniuses in particular aspect of science helping the human race, some soul having a hard time to integrate their bodies for whichever reason, some karmic accident or yet, some karmic debt to fulfill, or the attempt of nature at évolutions of the human specie (which i personnally doubt) or whatever other reason.

5. The need for letting steam off for all those involved in or around autism.

Now, find me a member, a moderator, a god who can take care in a coherent manner of all these needs amongst a large group of people from all over the world, in one thread, and i will lift my hat in admiration. This is a case were I wish we were using mind mapping and were having on topic detailed in lots of underneath topics, all regrouped with a single line of thinking/doing yet all independent at the same time.

It is really up to Tesla to decide how she wants to manage her thread, in view of the complexity of the topic. We here, can provide support, help, to whichever thread is being developed on the topic. So that all of us can benefit

Flash
17th February 2014, 16:43
Here on article that was posted by Carmody a few years ago in another thread http://projectavalon.net/forum4/showthread.php?20134-Adm.-George-Hoover-and-the-Roswell-secret-the-real-abilities-that-humans-have&p=416630&viewfull=1#post416630



Gene mutation in autism found to cause hyperconnectivity in brain's hearing center

New research from Cold Spring Harbor Laboratory (CSHL) might help explain how a gene mutation found in some autistic individuals leads to difficulties in processing auditory cues and paying spatial attention to sound.

The study has found that when a suspected autism gene called PTEN is deleted from auditory cortical neurons—the main workhorses of the brain's sound-processing center—the signals that these neurons receive from local as well as long-distance sources are strengthened beyond normal levels. These effects, the study shows, can be blocked by a drug currently in use as an immunosuppressant.

"It's long been hypothesized that autism spectrum disorders (ASDs) arise from a partial disruption of long-range connections in the brain during development," explains Professor Tony Zador, who led the study. "Our finding that PTEN-deficient neurons receive stronger inputs suggests that one way this disruption can be caused is by signal enhancement." His team's work appears in the Journal of Neuroscience on February 1.

Although ASDs could arise from mutations in any of dozens of candidate genes, a core triad of symptoms defines all cases: impaired language, impaired social interaction, and restricted and repetitive behaviors. "The challenge therefore has been to understand how this diverse set of candidate genes and the pathways they control converge to cause the common signature of ASDs," Zador says.

The auditory cortex, which plays a critical role in auditory attention and perception, forms functional connections with other sensory cortices and critical brain areas. The neural network within the auditory cortex has therefore been a target of studies aimed at understanding how alterations in neural circuits contribute to dysfunction in ASDs.

Zador's team focused for several reasons on the role of one suspected autism candidate gene, PTEN, on circuit alterations within the auditory cortex. Well known for its role as an anti-cancer gene that powers down cell growth, proliferation and survival, this gene has also been linked to ASDs by a slew of studies in humans and mice. PTEN mutations have been found in autistic individuals with extreme macroencephaly – an increase in brain volume. PTEN loss in mice has been found to boost cell size and the number of neuronal connections in the brain.

To decipher the role of PTEN on functional connectivity in the auditory cortex, Zador's group selectively disrupted the function of the PTEN gene in adult mice, only in a subset of neurons of the auditory cortex, while leaving the gene intact in neighboring neurons. The scientists then assessed the effect of the loss of PTEN on connectivity within the auditory cortex using techniques that involve stimulation by laser or flashes of blue light to trigger neuronal activity either locally or in other brain areas that send neuronal projections into the auditory cortex.

The rapid and robust increase in the strength of both long-range and local inputs observed following PTEN loss could possibly be explained by an increase that the scientists observed in the length and density of dendritic spines – the tiny, knob-like structures jutting out of a neuron that act like signal-receiving antennae.

These effects could be blocked, however, by chemically negating the effect of PTEN loss. One of the pathways regulated by the PTEN protein involves shutting down an intracellular enzyme called mTORC1, which promotes cell growth, among other things. Zador's group found that treating the PTEN-deficient mice for 10 days with the mTORC1-inhibitor rapamycin prevented an increase in dendritic spine number and signal strength.

While Zador is excited about "this finding that suggests that mTORC1 could be a good therapeutic target for some cases of PTEN-mediated brain disorders," he is also keen to further pursue his team's new evidence that cortical hyperconnectivity could be the "final pathway" by which diverse ASD genetic pathways lead to a single ASD phenotype. "Using cortical connectivity as a paradigm for assessing ASD candidate genes could provide insights into the mechanisms of the disorders and perhaps even give us clues to formulate new therapeutic strategies," he states.


More information: "PTEN regulation of local and long-range connections in mouse auditory cortex" appears in the Journal of Neuroscience on February 1.
http://medicalxpress.com/news/2012-01-gene-mutation-autism-hyperconnectivity-brain.html

Fairy Friend
18th February 2014, 09:45
It seems to me to make sense that even if some things listed above are a possible cause of autism then running tests maybe in order. Indeed, the very first poopy and peepee would be most informative. The urine showing the toxins being excreted including toxic exposure and viruses, bacteria and fungus and the feces showing probiotic profile (candida, bifidus, various acidophilus...) the presence of the right stuff in balance or inbalanced or the presence of bad probiotics, parasite, fungus etc., which tells us the body's ability to handle viruses, immunizations, allergies, etc. Dr. Natasha Campbell-McBride at Mercola.com

I believe we should be running the tests. My grandson has autism and was disappearing to me. His father has a nickel allergy. (which we have resistance by the doctor to test for it and was told it is rare but I know for a fact several people who have it. And we know dad has it??) My local well had high cadmium levels and so I began Epsom salt baths to detoxify him from metals. We saw an immediate affect.

I know that chelation therapy was mentioned however, I would hesitate on many chelators (EDTA-ethylene diamine tetra acetic acid) for they bind to the metals and form large molecules that the liver processes but it can fry your liver (nodule formation). It may be hard on a child's liver. I knew of one person (deceased) with Wilson's disease (allergy to copper) and had chelation therapy. It did fry his liver. Alternative to this is Zinc which blocks absorption of the copper present in foods or water in the intestines.

Yet since children get into the darndest places and fall into vats of toxins. It may be necessary to fry the liver. Most medical text will say 1/3 of the liver can regenerate, I saw a paper the stated 1/5 was left and the patient survived. With a very high protein diet it will regenerate and perhaps liver cleansing.

Please don't laugh at the falling into the vat of toxin, know of a child personally, pesticides, liver already fried. Idiot savant, could take a machine apart and rebuild it. Antisocial, easily overstimulated...t(2;19) never seen before, we published, 2003 I think at the UW cytogenetics lab. I did Fragile X testing, personally, although I questioned Angelman's syndrome del(15)(q11q13) another possible cause, same as autism with development, speech delays etc. but they laugh constantly, inappropriately, lots of hand flapping and flat heads, large lower jaw.

I think we saw an immediate affect from epsom salt baths, probiotics, juicing, really the more organic and natural the foods the better the results. People are having results here. Working on fermented foods yet and a hyperbaric chamber (oxygenating).

Music and play therapy, I had to manifest an expert here but she helped to bring him out and show us how to communicate with him. “Play to talk” by James MacDonald Ph.D. And Pam Stoika PhD.

We could proceed better if we knew sugar is off, ran neural scans, they have a wheat-gluten allergy, mercury present if we ran a lot of tests and saw the results. Each maybe rare but collectively I think there is a pay off.

Chanlo23
18th February 2014, 18:48
Some resource links for Autism research. They are likely too remedial for those who have been engaged in Autism research for a long time, but may be useful for newbies:


Autism Research Institute (http://www.autism.com/) ARI is a nonprofit organization devoted to conducting research on the triggers of autism and on methods of diagnosing and treating autism and they provide this research-based information to parents and professionals affected by autism spectrum disorders.

Autism Research at the NICHD (http://www.nichd.nih.gov/health/topics/autism/Pages/default.asp) The goal of this site is to provide easy access to the most current information about NICHD research projects, publications, news releases, and other activities related to autism and similar disorders.

Autism Research Network (http://www.nichd.nih.gov/health/topics/autism/Pages/default.aspx) The Autism Research Network, part of the National Institutes of Health (NIH), supports research dedicated to understanding and treating autism. This site provides information about the Collaborative Programs of Excellence in Autism (CPEA) Network, dedicated to research about the cause of autism, and the Studies to Advance Autism Rsesearch and Treatment (STAART) Network, dedicated to research on treatments.

Cambridge Center for Behavioral Studies (http://www.behavior.org/) Applied behavior analysis methods of autism intervention. Good Website for learning more about this educational approach.

MCH Library Knowledge Path: Autism Spectrum Disorders (http://www.mchlibrary.info/KnowledgePaths/kp_autism.html) An online collection of resources about ASD for path for health professionals, educators, researchers, policymakers, and families.

PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for biomedical articles back to the 1950s. PubMed includes links to full text articles and other related resources.

Research Autism (http://researchautism.net/pages/welcome/home.ikml) Research Autism is the only UK charity dedicated to research into interventions in autism. We commission, carry out and support high quality, independent research into new and existing health, education, social and other interventions. Our website at is one of the biggest, most up-to-date, and most reliable websites in the world for information about autism interventions.

Rich Center for Autism at Youngstown State University (http://ysu.edu/richcenter/) A national facility for the study and treatment of autism for distance learning technology and programs.

The Autism Autoimmunity Project (TAAP) (http://www.taap.info/epidemic.asp) Funds independent research addressing immune and immunogenetic abnormalities in autism.

UC Davis M.I.N.D. Institute (http://www.ucdmc.ucdavis.edu/MINDInstitute/) The M.I.N.D. Institute is dedicated to understanding the causes and to help develop better treatments and ultimately cures for neurodevelopmental disorders.
IAN Project (https://www.ianresearch.org/) This is an innovative online initiative connecting researchers with families affected by autism spectrum disorders (ASD). This dynamic exchange is not only helping to influence public policy, but could lead to important breakthroughs about causes, diagnosis, treatments, and a possible cure.
Summary of Dietary, Nutritional and Medical Treatments for Autism (http://www.autism.com/index.php//adams) This document is intended to provide a simple summary for families and physicians of the major dietary, nutritional, and medical treatments available to help children and adults with autism spectrum disorders. The discussion is limited to those treatments which have scientific research support, with an emphasis on nutritional interventions. This report excludes psychiatric medications for brevity. The dietary, nutritional, and medical treatments discussed here will not help every individual with autism, but they have helped thousands of children and adults improve, usually slowly and steadily over months and years, but sometimes dramatically. This summary is primarily based on review of the scientific literature, and includes over 150 references to peer-reviewed scientific research studies.

Chanlo23
18th February 2014, 19:05
More Links:


Measles map exposes global fallout of an autism scare campaign (http://www.theaustralian.com.au/news/world/measles-map-exposes-global-fallout-of-an-autism-scare-campaign/story-fnb64oi6-1226828830190#) This map/article purports to show that wherever autism activists and campaigned against vaccines, there has been a rise in preventable diseases. Does anyone have links to research linking Autism to vaccines that has not been discredited and/or has been supported by additional research?

SFARI Gene is an evolving database for the autism research community that is centered on genes implicated in autism susceptibility. (https://sfari.org/resources/sfari-gene) The SFARI Gene web portal seamlessly integrates different kinds of genetic data that are being generated by research studies, and in so doing encourages the generation of new hypotheses.

Top-ten-advances-autism-research-2013 (http://www.autismspeaks.org/science/science-news/autism-speaks-top-ten-advances-autism-research-2013) The year 2013 brought signs of a gratifying maturation in autism research. From whole genome sequencing to the presence of good bacteria.



Thanks!

Sierra
19th February 2014, 17:47
Hello :)

This thread has been split into two threads, one for research papers (Tesla's thread here), and the other for a discussion of autism.

I had to delete some posts, that did not seem to fit anywhere, so the discussion may seem disjointed on both threads. I apologize if I have offended anyone (this was a difficult thread to split). I saved the posts that did not end up on either thread, so contact me if you want your missing post(s) to be added back in to a thread.

The new thread is called "Autism Discussion", and it is located in General Discussion.

http://projectavalon.net/forum4/showthread.php?68633-Autism-Discussion&p=789571&viewfull=1#post789571

Thank you for your patience and understanding.

Sierra

Hervé
20th February 2014, 03:03
Toxic Chemicals Linked to 'Global, Silent Pandemic' Striking Children Worldwide (http://www.commondreams.org/headline/2014/02/17-2)
Published on Monday, February 17, 2014 by Common Dreams (http://www.commondreams.org)


"The presumption that new chemicals and technologies are safe until proven otherwise is a fundamental problem," study authors write

- Andrea Germanos, staff writer
Toxic chemicals including some pesticides and solvents may be behind the increasing number of cases of neurodevelopmental disabilities—including autism and attention-deficit hyperactivity disorder—among children, researchers warn.

"We have the methods in place to test industrial chemicals for harmful effects on children's brain development—now is the time to make that testing mandatory," stated study co-author Philippe Grandjean. The findings are presented in a study (http://www.thelancet.com/journals/laneur/article/PIIS1474-4422%2813%2970278-3/abstract) by Philippe Grandjean, adjunct professor of environmental health at Harvard School of Public Health (HSPH) and Philip Landrigan, Dean for Global Health at Mount Sinai published online Saturday in Lancet Neurology.

"The greatest concern is the large numbers of children who are affected by toxic damage to brain development in the absence of a formal diagnosis. They suffer reduced attention span, delayed development and poor school performance. Industrial chemicals are now emerging as likely causes," said Grandjean.

The new study follows similar research by the authors published in 2006 in which they reviewed clinical and epidemiological studies and identified five industrial chemicals as developmental neurotoxicants: lead, methylmercury, polychlorinated biphenyls, arsenic and toluene.

Grandjean and Landrigan's current review updates that list and adds six newly recognized developmental neurotoxicants: manganese, fluoride, chlorpyrifos and DDT (pesticides), tetrachloroethylene (a solvent), and the polybrominated diphenyl ethers (often used as flame retardants).

Manganese has been linked to diminished intellectual function and impaired motor skills, and solvents have been linked to hyperactivity and aggressive behavior, the authors write.

The effects of neurotoxicity can be society-wide, the authors note, as loss of IQ points may bring down earnings thereby affecting GDP. They can be costly as well; for example, the annual cost of lead poisoning in the U.S. is $50 billion, while behavioral problems associated with neurotoxicant exposure could also require special educational services and may even lead to incarceration, the authors write.

"The presumption that new chemicals and technologies are safe until proven otherwise is a fundamental problem," the authors write, adding, "Voluntary controls seem to be of little value."

To confront this "global, silent pandemic," the authors urge an international strategy that takes a precautionary approach to fully evaluate new chemicals before they hit the markets. Testing on industrial chemicals and pesticides already on the market should also take place, they say.

"The problem is international in scope, and the solution must therefore also be international," Grandjean stated. "We have the methods in place to test industrial chemicals for harmful effects on children's brain development—now is the time to make that testing mandatory."

____________________
This work is licensed under a Creative Commons Attribution-Share Alike 3.0 License.

Chanlo23
21st February 2014, 19:05
I have been trying to research prescription medications used in the treatment of Autism. I find it interesting that atypical antipsychotics are/have been prescribed for hyperactivity and aggressiveness. Has anyone seen newer research on medication for symptomology?


Medicines treating core symptoms (http://www.autismspeaks.org/what-autism/treatment/medicines-treating-core-symptoms). Medicines for treating the three core symptoms of autism – communication difficulties, social challenges and repetitive behavior – have long represented a huge area of unmet need. Unfortunately, few drugs on the market today effectively relieve these symptoms and none of the options most often prescribed by practitioners work well for every individual. In fact, while the Food and Drug Administration (FDA) has approved two drugs for treating irritability associated with the autism (risperidone and aripiprazole), it has yet to approve a medicine for treating autism’s three core characteristics. Nonetheless, medicines such as risperidone and aripiprazole can be beneficial in ways that can ease these core symptoms, because relieving irritability often improves sociability while reducing tantrums, aggressive outbursts and self-injurious behaviors. The good news is that the range of medication options may soon change, thanks to recent advances in our understanding of the biology that produces autism’s core symptoms. This has made it possible for researchers to begin testing compounds that may help normalize crucial brain functions involved in autism. Early experiments suggest that several compounds with different mechanisms of action have great potential for clinical use, and many are now in clinical trials.

NIH Study on the use of Anti-psychotics for Autism (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171144/) Although this study is from 2008, its results may still be 'coloring' research and treatment. Summary: Atypical antipsychotics have become indispensable in the treatment of a variety of symptoms in autism. They are frequently used to treat irritability and associated behaviors including aggression and self injury. They may also be efficacious for hyperactivity and stereotyped behavior. This review presents the rationale for the use of this drug class in autism and reviews the most important studies published on this topic to date. Significant adverse effects, including weight gain and the possibility of tardive dyskinesia, are reviewed. Future research directions are discussed.

Drugs-medication-for-autism. (http://www.newsmax.com/FastFeatures/Drugs-medication-for-autism/2011/01/12/id/382640) Summary of 5 prescription drugs for Autism treatment (from 2011). Being a neural disorder, autism cannot be treated through medicines. Medical practitioners use drugs in cases of autism solely to treat and manage symptoms. Five major drug categories are regularly used for symptomatic treatment: Selective serotonin reuptake inhibitors (SSRIs) (for anxiety, depression, and obsessive-compulsive disorder (OCD); Anti psychotic drugs (old usage) like Haloperidol, Chlorpromazine, Thioridazine, and Fluphenazine (controlling the intensity of the neurotransmitter dopamine in the brain; Anti psychotic (new) - Risperidone (aggression and self-injury among autistic children with fewer side effects); Anti-convulsants to control seizures; Stimulants (e.g. Ritalin) for control and treat the autistic tendencies of inattention and hyperactivity. Apart from these medications, vitamin B6 is being tested as a drug to stimulate brain activity. However, and to reiterate, none of these drugs can be seen as a direct treatment for autism. They are medications for symptomatic relief, with long-term therapy being the only viable treatment for autism.

Tesla_WTC_Solution
27th February 2014, 06:12
regarding prescriptions, a common mistake is Risperdal.

http://en.wikipedia.org/wiki/Risperidone

Some of the moms and dads in my King County Washington autism support email group say their kids developed Tardive Dyskinesia after being exposed to the drug.
One of the girls is aged 11 and no longer displays many of her normal reflexes after being on Risperdal.

Also Paxil was linked to Fragile X when the parents took it.

So... try the ALTERNATIVES to these, if you can, based on educated advice (experience of parents who tried that).

:(


Deplin is a good prescription, Chanlo23, it's a treated B vitamin made specially for people with auto immunity to Folate receptors.
Us autistic people just keep showing up in the Drs office so much, they are starting to see what's going on.

what on earth would cause an allergy to folate receptors?
sounds fishy doesnt it?

Tesla_WTC_Solution
1st March 2014, 02:27
Here is a massively fishy article, in terms of vaccine administration predating PTSD -- these doctors say that before PTSD develops, the troops' bodies and brains become INFLAMED, like the director who just died (Ramis?) of inflammatory autoimmune vasculitis :( holy crap right?

http://www.medpagetoday.com/Psychiatry/AnxietyStress/44519?xid=nl_mpt_DHE_2014-02-28&utm_content=&utm_medium=email&utm_campaign=DailyHeadlines&utm_source=WC&eun=g738235d0r&userid=738235&email=millerr2009%40live.com&mu_id=5906468

Inflammation May Be PTSD Risk Factor
Published: Feb 27, 2014 | Updated: Feb 27, 2014

By John Gever, Deputy Managing Editor, MedPage Today
Reviewed by F. Perry Wilson, MD, MSCE; Instructor of Medicine, Perelman School of Medicine at the University of Pennsylvania and Dorothy Caputo, MA, BSN, RN, Nurse

High levels of C-reactive protein (CRP), an inflammation marker, were seen in soldiers who later developed post-traumatic stress disorder, researchers said.

Among U.S. Marines and Navy personnel who consented to participate in a prospective study, each 10-fold increment in CRP levels at pre-deployment baseline was associated with a 51% increased likelihood of showing at least one PTSD symptom after deployment to Iraq or Afghanistan (odds ratio 1.51, 95% CI 1.15-1.97, P=0.003), reported Dewleen Baker, MD, of the VA Healthcare System in San Diego, and colleagues.

Writing online in JAMA Psychiatry, the researchers proposed that inflammation may predispose people to develop PTSD.

"If peripheral inflammation contributes to the development of PTSD, interventions to decrease inflammation, such as dietary or lifestyle modifications, might ameliorate the severity of this disorder," they wrote.

Paul E. Schulz, MD, of the University of Texas Health Science Center in Houston, who was not involved with the study, told MedPage Today that a clinical study "to investigate whether lowering CRP leads to a reduced incidence of developing PTSD" would help confirm a cause-and-effect relationship.

Another scholar not associated with the study said it highlighted an exciting area in PTSD research.

"The immune system is really a very complex part of the body, and I think we are just now beginning to understand its role in interactions with psychiatric illness," said Bruce Capehart, MD, of Duke University.

But he suggested that it would be premature to accept the current study as proof that inflammation is causative in PTSD.

He pointed to a lack of "dose-response" in the study -- in particular, that participants with baseline CRP levels higher than 10 ng/mL (well above the mean of 1.93 ng/mL) did not show significantly higher risk of PTSD than those with lower but still above-average CRP values.

"To look at it as one-way causation may not be that simple," Capehart said. "We may be looking at a two-way relationship there. Maybe there is a susceptibility there for some people to have a modestly elevated inflammatory state and a simultaneous greater risk for developing an anxiety disorder."

Study Design and Results

The analysis was part of the prospective Marine Resiliency Study, in which a total of 2,610 Marines and Navy sailors in four cohorts were recruited prior to war-theater deployment for baseline testing and subsequent medical and psychiatric follow-up. Participants were considered physically healthy at baseline.

Psychiatric follow-up was conducted after the conclusion of 7-month deployments at 3 months and again at 6 months. Data from both visits were available for 1,617 participants.

Mean participant age was about 23 but ranged from 18 to 48. CRP levels at baseline averaged 1.93 ng/mL (SD 3.31); the median level was 0.79 and the full range was 0.03 to 28.53. About half the cohort had been deployed before and the median time in military service was 3 years.

PTSD was evaluated with the Clinician-Administered PTSD Scale (CAPS); mean baseline scores were 14.89 (SD 15.37). Other psychiatric assessments included the Beck anxiety and depression scales. Participants were asked about deployment-related trauma at the 3-month visit.

Overall, the prevalence of PTSD did not change markedly post- versus pre-deployment. Diagnoses of PTSD were made in 4.7% of participants at baseline and in 6.3% and 5.1% at the 3- and 6-month evaluations after conclusion of deployment.

Mean CAPS scores at the 3- and 6-month points were 17.40 (SD 18.01) and 15.41 (SD 17.39), respectively (P versus baseline not reported).

Baker and colleagues used a statistical method called zero-inflated negative binomial regression for their analyses of baseline factors in association with post-deployment CAPS scores. This was intended to compensate for data distributions "that have an excess of zeroes in addition to being positively skewed," they explained.

Under this method, measures of combat exposure and potentially traumatic battlefield experiences were significantly associated with CAPS scores at the 3-month post-deployment visit, with odds ratios of 1.03 (95% CI 1.01-1.05) and 1.08 (95% CI 1.03-1.13), respectively in a "zero model" indicating presence versus absence of any PTSD symptom.

In a "count model," indicating the extent of symptoms when present, scores for combat exposure, battlefield experience, and 10-fold increment in CRP were associated with post-deployment CAPS score as follows:

Combat exposure: OR 1.01 (P=0.001)
Battlefield experience: OR 1.04 (P<0.001)
Log CRP: OR 1.06 (P=0.09)
Looking at the data more simply, Baker and colleagues calculated that, after adjusting for combat exposure and battlefield experience scores, those with PTSD symptoms at the 6-month visit had mean baseline CRP levels of 1.0 ng/mL, versus about 0.77 ng/mL for those without post-deployment symptoms (P<0.05).

What Does It Mean?

Schulz said the inflammation-PTSD relationship was definitely plausible on the basis of several lines of research. For example, he told MedPage Today in an email, previous traumatic brain injury is a known risk factor for PTSD, and the mechanism may involve chronic brain inflammation resulting from the injury. Other lines of research have implicated immunological factors in promoting susceptibility to PTSD, he said.

But he acknowledged that CRP in the study could also have served as a marker for pre-existing stress and anxiety.

"Several of the papers we reviewed as part of a 'review of the risk factors for PTSD' suggested that a personal history of anxiety, a family history of anxiety, and a family history of depression, are risk factors for developing PTSD," Schulz said. He also noted that previous research had identified dozens of other risk factors for PTSD.

Psychologist David Blackburn, PhD, of Temple Mental Health Center in Temple, Texas, part of the Scott & White Healthcare system, who also was not involved with the study, told MedPage Today that future investigations into the relationship should take a broader perspective.

"I think subsequent research needs to not only involve military members who have PTSD, but also civilians who also have PTSD; this would strengthen the study," he said in an email. "In addition, more longitudinal studies over longer periods of time would also strengthen the relationship are proposing."

Capehart said the complexity of the mind-body relationship when it comes to PTSD "makes it a very exciting time to be practicing psychiatry."

The study was funded by the U.S. government.

Authors declared they had no relevant financial interests.

______________________________________________________________-





Also please read:

http://www.ncbi.nlm.nih.gov/pubmed/23337946

Mol Psychiatry. 2014 Feb;19(2):259-64. doi: 10.1038/mp.2012.197. Epub 2013 Jan 22.
[B]Elevated maternal C-reactive protein and autism in a national birth cohort.

Brown AS1, Sourander A2, Hinkka-Yli-Salomäki S3, McKeague IW4, Sundvall J5, Surcel HM6.
Author information
Abstract

Autism is a complex neuropsychiatric syndrome with a largely unknown etiology. Inflammation during pregnancy may represent a common pathway by which infections and other insults increase risk for the disorder. Hence, we investigated the association between early gestational C-reactive protein (CRP), an established inflammatory biomarker, prospectively assayed in maternal sera, and childhood autism in a large national birth cohort with an extensive serum biobank. Other strengths of the cohort included nearly complete ascertainment of pregnancies in Finland (N=1.2 million) over the study period and national psychiatric registries consisting of virtually all treated autism cases in the population. Increasing maternal CRP levels, classified as a continuous variable, were significantly associated with autism in offspring. For maternal CRP levels in the highest quintile, compared with the lowest quintile, there was a significant, 43% elevated risk. This finding suggests that maternal inflammation may have a significant role in autism, with possible implications for identifying preventive strategies and pathogenic mechanisms in autism and other neurodevelopmental disorders.
PMID: 23337946 [PubMed - in process] PMCID: PMC3633612 [Available on 2014/8/1]
Grant Support

__________________________________________________________


I wonder if any ex military women are having normal kids at all anymore!!!!!!!!!!

sheme
7th March 2014, 15:32
http://www.smh.com.au/national/health/study-finds-toxic-chemicals-linked-to-autism-adhd-20140215-32snz.html

A link posted by fellow Avalonian in another thread. Thought I would pop it in here.

Tesla_WTC_Solution
8th March 2014, 03:36
http://www.smh.com.au/national/health/study-finds-toxic-chemicals-linked-to-autism-adhd-20140215-32snz.html

A link posted by fellow Avalonian in another thread. Thought I would pop it in here.


Thank you for this. Feel free to expand your post to include text if you like!
I appreciate the article :) it's very good!

Ellisa
9th March 2014, 02:20
Fragile X is understood well in its genetic transmission and outcome. There is genetic testing available for the detection of risk. Fragile X is usually carried by the female, but sometimes the male also has the marker. Then all children born to that couple will have the condition. It is not influenced by external factors and, as far as I know, there no treatment. Usually boys have the more serious form of the condition, though girls can be affected too. In some people the symptoms are very mild, even absent, and are unsuspected, though the person (usually female) may carry it.

Children with Fragile X can have autism, epilepsy, etc, They are just as likely as anyone else to develop these other conditions, but their Fragile X diagnosis would have been predictable, and is present at birth. It may also be present in siblings and relatives.

Autism and Fragile X are not the same, and do not have the same cause.

Agape
15th March 2014, 12:39
http://www.dailygalaxy.com/my_weblog/2013/12/human-brain-found-to-develop-in-distinct-stages.html

"Human Brain Develops in Distinct Stages of Genetic Activity" --New Discovery

The human brain develops with an exquisitely timed choreography marked by distinct patterns of gene activity at different stages from the womb to adulthood, report Yale researchers. The Yale team conducted a large-scale analysis of gene activity in cerebral neocortex —an area of the brain governing perception, behavior, and cognition — at different stages of development.

The team found that the human brain is more like a neighorhood, which is better defined by the community living within its borders than its buildings.
“The neighborhoods get built quickly and then everything slows down and the neocortex focuses solely on developing connections, almost like an electrical grid,” said Nenad Sestan, professor of neurobiology at Yale’s Kavli Institute for Neuroscience and senior author of the study. . “Later when these regions are synchronized, the neighborhoods begin to take on distinct functional identities like Little Italy or Chinatown.”

The analysis shows the general architecture of brain regions is largely formed in the first six months after conception by a burst of genetic activity, which is distinct for specific regions of the neocortex. This rush is followed by a sort of intermission beginning in the third trimester of pregnancy. During this period, most genes that are active in specific brain regions are quieted — except for genes that spur connections between all neocortex regions. Then in late childhood and early adolescence, the genetic orchestra begins again and helps subtly shape neocortex regions that progressively perform more specialized tasks, a process that continues into adulthood.

The analysis is the first to show this “hour glass” sketch of human brain development, with a lull in genetic activity sandwiched between highly complex patterns of gene expression, said Sestan. Intriguingly, say the researchers, some of the same patterns of genetic activity that define this human “hour glass” sketch were not observed in developing monkeys, indicating that they may play a role in shaping the features specific to human brain development.

The findings emphasize the importance of the proper interplay between genes and environment in the child’s earliest years after birth when the formation of synaptic connections between brain cells becomes synchronized, which shape how brain structures will be used later in life, said Sestan. For instance, disruptions of in synchronization of synaptic connections during child’s earliest years have been implicated in autism.

The neocortex, Latin for "new bark," is our third, newly human brain in terms of evolution. It is what makes possible our judgments and our knowledge of good and evil. It is also the site from which our creativity emerges and home to our sense of self.

The Neocortex writes Carl Sagan in Cosmos, is where "matter is transformed into consciousness." It comprises more than two-thirds of our brain mass. The realm of intuition and critical analysis,--it is the Neocortex where we have our ideas and inspirations, where we read and write, where we compose music or do mathematics. "It is the distinction of our species," writes Sagan,"the seat of our humanity. Civilization is the product of the cerebral cortex."

Each cubic millimeter of tissue in the neocortex, reports Michael Chorost in World Wide Mind, contains between 860 million and 1.3 billion synapses. Estimates of the total number of synapses in the neocortex range from 164 trillion to 200 trillion. The total number of synapses in the brain as a whole is much higher than that. The neocorex has the same number of neurons as a galaxy has stars: 100 billion.

Researcher sestimate that with current technology it would take 10,000 automated microscopes thirty years to map the connections between every neuron in a human brain, and 100 million terabytes of disk space to store the data.

Self-aware, language-using, tool-making brains are very new in the evolutionary timeline, some 200,000-years old. Most of the neurons in the neocortex have between 1,000 and 10,000 synaptic connections with other neurons. Elsewhere in the brain, in the cerebellum, one type of neuron has 150,000 to 200,000 synaptic connections with other neurons. Even the lowest of these numbers seems hard to believe. One tiny neuron can connect to 200,000 neurons.

The image at the top of the page shows the neocortex organised into thousands of columns of neurons. Each column has a diameter of 0.5mm and contains 10,000 neurons. The neocortex is also organised into 6 layers. In the background are other neurons making up the neocortical column.

Mihovil Pletikos, Andre ́ M.M. Sousa, and Goran Sedmak of Yale are co-lead authors of the Yale study. Other Yale authors are Kyle A. Meyer, Ying Zhu, Feng Cheng, Mingfeng Li and Yuka Imamura Kawasawa.

The work was funded by the National Institute of Mental Health, the James S. McDonnell Foundation, and the Kavli Foundation.

:car:

Tesla_WTC_Solution
15th March 2014, 16:40
That's a very superb article.

It reminds me, we were talking earlier about how Proteins control the expression of genes,
and more work needed to be done regarding what factors alter the expression of genes without obvious DNA cutting.

Things have progressed a lot since Dr. Mengele, I'm sad to say.

Thank you though, good read, many things I would do differently or not at all re: autism :(




p.s. my boy was vocal for about 40 minutes of my visit yesterday.
I always try to get him to talk/sing/make noise. He was actually being sorta loud!
Exercising his vocal cords and mouth.

I think many of these kids just have incorrect nerve connection to their mouths!!!

Could this be affected by the "neighborhoods of the brain" not lining up correctly?

Tesla_WTC_Solution
30th March 2014, 16:07
I've taken an interest in Childhood Apraxia of Speech because of what I've seen with the autistic kids.

http://en.wikipedia.org/wiki/Apraxia_of_speech


Apraxia of speech (AOS) is an acquired oral motor speech disorder affecting an individual's ability to translate conscious speech plans into motor plans, which results in limited and difficult speech ability. By the definition of apraxia, AOS affects volitional (willful or purposeful) movement patterns, however AOS usually also affects automatic speech.[1]

Individuals with AOS have difficulty connecting speech messages from the brain to the mouth.[2] AOS is a loss of prior speech ability resulting from a stroke, brain injury, or progressive illness.

Developmental verbal dyspraxia (DVD), also known as childhood apraxia of speech (CAS) and developmental apraxia of speech (DAS);[3][4] is an inability to utilize motor planning to perform movements necessary for speech during a child's language learning process. Although the causes differ between AOS and DVD, the main characteristics and treatments are similar.[2][5]

Apraxia of speech (AOS) is a neurogenic communication disorder affecting the motor programming system for speech production.[6][7] Individuals with AOS demonstrate difficulty in speech production, specifically with sequencing and forming sounds. The Levelt model describes the speech production process in the following three consecutive stages: conceptualization, formulation, and articulation. According to the Levelt model, apraxia of speech would fall into the articulation region. The individual does not suffer from a language deficiency, but has difficulty in the production of language in an audible manner. Notably, this difficulty is limited to vocal speech, and does not affect signed language production. [8] The individual knows exactly what they want to say, but there is a disruption in the part of the brain that sends the signal to the muscle for the specific movement.[7] Individuals with acquired AOS demonstrate hallmark characteristics of articulation and prosody (rhythm, stress or intonation) errors.[6][7] Coexisting characteristics may include groping and effortful speech production with self-correction, difficulty initiating speech, abnormal stress, intonation and rhythm errors, and inconsistency with articulation.[9]

Wertz et al., (1984) describe the following five speech characteristics that an individual with apraxia of speech may exhibit:[9]

Effortful trial and error with groping
Groping is when the mouth searches for the position needed to create a sound. When this trial and error process occurs, sounds may be held out longer, repeated or silently voiced. In some cases, an AOS sufferer may be able to produce certain sounds on their own, easily and unconsciously, but when prompted by another to produce the same sound the patient may grope with their lips, using volitional control (conscious awareness of the attempted speech movements), while struggling to produce the sound.[7]
Self correction of errors
Patients are aware of their speech errors and can attempt to correct themselves. This can involve distorted consonants, vowels, and sound substitutions. People with AOS often have a much greater understanding of speech than they are able to express. This receptive ability allows them to attempt self correction.[10]
Abnormal rhythm, stress and intonation
Sufferers of AOS present with prosodic errors which include irregular pitch, rate, and rhythm. This impaired prosody causes their speech to be: too slow or too fast and highly segmented (many pauses). An AOS speaker also stresses syllables incorrectly and in a monotone. As a result, the speech is often described as 'robotic'. When words are produced in a monotone with equal syllabic stress, a word such as 'tectonic' may sound like 'tec-ton-ic' as opposed to 'tec-TON-ic'. These patterns occur even though the speakers are aware of the prosodic patterns that should be used.[11]
Inconsistent articulation errors on repeated speech productions of the same utterance
When producing the same utterance in different instances, a person with AOS may have difficulty using and maintaining the same articulation that was previously used for that utterance. On some days, people with AOS may have more errors, or seem to "lose" the ability to produce certain sounds for an amount of time. Articulation also becomes more difficult when a word or phrase requires an articulation adjustment, in which the lips and tongue must move in order to shift between sounds. For example, the word "baby" needs less mouth adjustment than the word "dog" requires, since producing "dog" requires two tongue/lips movements to articulate.[6]
Difficulty initiating utterances
Producing utterances becomes a difficult task in patients with AOS, which result in various speech errors. The errors in completing a speech movement gesture may increase as the length of the utterance increases. Since multisyllabic words are difficult, those with AOS use simple syllables and a limited range of consonants and vowels.[6][7]
Diagnosis[edit]

Apraxia of speech can be diagnosed by a speech language pathologist (SLP) through specific exams that measure oral mechanisms of speech. The oral mechanisms exam involves tasks such as pursing lips, blowing, licking lips, elevating the tongue, and also involves an examination of the mouth. A complete exam also involves observation of the patient eating and talking. SLPs do not agree on a specific set of characteristics that make up the apraxia of speech diagnosis,[citation needed] so any of the characteristics from the section above could be used to form a diagnosis.[2] Patients may be asked to perform other daily tasks such as reading, writing, and conversing with others. In situations involving brain damage, an MRI brain scan also helps identify damaged areas of the brain.[2]

A differential diagnosis must be used in order to rule out other similar or alternative disorders. Although disorders such as expressive aphasia, conduction aphasia, and dysarthria involve similar symptoms as apraxia of speech, the disorders must be distinguished in order to correctly treat the patients.[citation needed] While AOS involves the motor planning or processing stage of speech, aphasic disorders can involve other language processes.[12]

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033475/
J Autism Dev Disord. Author manuscript; available in PMC Apr 1, 2012.
Published in final edited form as:
J Autism Dev Disord. Apr 2011; 41(4): 405–426.
doi: 10.1007/s10803-010-1117-5
PMCID: PMC3033475
NIHMSID: NIHMS244664
The Hypothesis of Apraxia of Speech in Children with Autism Spectrum Disorder
Lawrence D. Shriberg,a Rhea Paul,b Lois M. Black,c and Jan P. van Santenc


Abstract
In a sample of 46 children aged 4 to 7 years with Autism Spectrum Disorder (ASD) and intelligible speech, there was no statistical support for the hypothesis of concomitant Childhood Apraxia of Speech (CAS). Perceptual and acoustic measures of participants’ speech, prosody, and voice were compared with data from 40 typically-developing children, 13 preschool children with Speech Delay, and 15 participants aged 5 to 49 years with CAS in neurogenetic disorders. Speech Delay and Speech Errors, respectively, were modestly and substantially more prevalent in participants with ASD than reported population estimates. Double dissociations in speech, prosody, and voice impairments in ASD were interpreted as consistent with a speech attunement framework, rather than with the motor speech impairments that define CAS. Key Words: apraxia, dyspraxia, motor speech disorder, speech sound disorder

A continuing question about persons with Autism Spectrum Disorder (ASD) is whether reported diminished abilities in gross, fine, and oral motor control are causally associated with reported deficits in speech acquisition and performance. The classification term for the speech deficit in question, recently adapted by the American Speech-Language-Hearing Association (ASHA; 2007a, 2007b), is Childhood Apraxia of Speech (CAS). Medical literatures and speech literatures in other countries continue to prefer several other classificatory terms for this disorder, including dyspraxia and developmental verbal dyspraxia. “Childhood” apraxia of speech differentiates congenital and early acquired forms of apraxia of speech from adult acquired forms, but creates a nosological problem because childhood apraxia of speech generally persists into adulthood. We will use the ASHA (2007a) recommended term— CAS.

The strong form of the hypothesis in the title of this paper, hereafter, the ‘CAS-ASD’ hypothesis, is that CAS is a sufficient cause of lack of speech development in at least some children classified as nonverbal ASD. The weak form of the CAS-ASD hypothesis is that CAS contributes to the inappropriate speech, prosody, and/or voice features reported in some children and adults with verbal ASD. Although the present report addresses only the weak form of the hypotheses, the conceptual framework and implications for treatment apply to both forms of the hypothesis. Forthcoming research addresses the strong form of the hypothesis. The following sections provide (a) rationales for the CAS-ASD hypothesis, (b) an overview of idiopathic speech sound disorders, and (c) a summary of speech, prosody, and voice findings in verbal ASD.

Rationales for the CAS-ASD Hypothesis

The American Speech-Language-Hearing Association Position Statement recommends the following definition of CAS:

Childhood apraxia of speech (CAS) is a neurological childhood (pediatric) speech sound disorder in which the precision and consistency of movements underlying speech are impaired in the absence of neuromuscular deficits (e.g., abnormal reflexes, abnormal tone). CAS may occur as a result of known neurological impairment, in association with complex neurobehavioral disorders of known or unknown origin, or as an idiopathic neurogenic speech sound disorder. The core impairment in planning and/or programming spatiotemporal parameters of movement sequences results in errors in speech sound production and prosody. (p. 1)

Three conceptual and empirical perspectives motivate the hypothesis that CAS may be causal to the absence of speech development in some children with ASD or in others, to perceptible differences in speech, prosody, or voice.

Motor skills
A primary rationale for the CAS-ASD hypothesis is findings indicating that persons with ASD have praxis deficits affecting imitative processes and impairing acquisition and performance of a range of motor skills. Reviews of this literature and the neural correlates of praxis findings in ASD are beyond the scope of the present report; for representative data and overviews of research during the past two decades see Dawson, Mottron, and Gernsbacher (in press); Dowell, Mahone, and Mostofsky (2009); Dziuk et al. (2007); Gernsbacher, Sauer, Geye, Schweigert, and Goldsmith (2008); Green et al. (2002); Goldman Gross and Grossman (2008); McDuffie et al. (2007); Mostofsky, Burgess, and Gidley Larson (2007); Mostofsky et al. (2006); Ozonoff et al. (2008); Page and Boucher (1998); Rogers (2009); Rogers, Bennetto, McEvoy, and Pennington (1996); Russo, Larson, and Kraus (2009); Smith and Bryson (1994); Vivanti, Nadig, Ozonoff, and Rogers (2008); and Zadikoff and Lang (2005). A parsimonious extension of the findings from studies in other motor domains is that a praxic deficit in speech may account for the failure of some children with ASD who have adequate cognitive ability and communicative intent to acquire articulate speech (the strong version of the CAS-ASD hypothesis), and for others with ASD to have atypical speech, prosody, and/or voice (the weak version of the CAS-ASD hypothesis). As reviewed in the following sections, CAS is the one subtype of speech sound disorder whose neurobehavioral substrates could account for the speech, prosody, and voice findings reported in ASD (Shriberg 2010a, 2010b). Unlike dysarthria, a class of neuromuscular speech disorders that constrains the precision of speech production, the transcoding (planning/programming) deficits that define CAS (van der Merwe, 2009) are functionally sufficient to disrupt the onset of speech and/or speech precision and stability.

A constraint on the CAS-ASD hypothesis is that many speech researchers have concluded from diverse conceptual and empirical considerations that speech is domain specific (e.g., Dewey, Roy, Square-Storer, & Hayden, 1988; Kent, 2000, 2004, 2010; McCauley, Strand, Lof, Schooling, & Frymark, 2009; Potter, Kent, & Lazarus, 2009; Smith, 2006; Weismer, 2006; Watkins, Dronkers, & Vargha-Khadem, 2002; Ziegler, 2002, 2008). The perspectives in these and other sources are that the neural substrates of apraxia of speech differ from the neural substrates posited for other motor systems and other types of apraxia (e.g., oromotor apraxia, limb apraxia, ideomotor apraxia).

A recent empirical constraint on the CAS-ASD hypothesis are results discussed in Pickett, Pullara, O’Grady, and Gordon (2009), which summarizes findings from reports of 167 individuals with nonverbal ASD who acquired speech at age 5 or older. Records indicated that these individuals learned skills including “imitating sounds, words, and phrases,” “answering simple questions,” “requesting spontaneously,” “using complete sentences,” and “speaking in spontaneous complex sentences” (p.13). Crucially for the strong version of the CAS-ASD hypothesis, however, the speech findings in Table 1 of Pickett et al. (2009) do not include information consistent with the signs of CAS described later in the present report.

Genomics
A second rationale for the CAS-ASD hypothesis is based on the possibility of common genetic origins. Whereas numerous candidate genes and regions of interest for autism spectrum disorders have been reported, the widely-studied FOXP2 transcription gene is the only gene to date associated with CAS. The origins of both disorders are viewed as strongly heritable and both involve cognitive-linguistic impairments, suggesting the possibility of genes common to both disorders (e.g., Poot et al., 2010; Vernes et al., 2008).

A constraint on the likelihood of inherited or sporadic genetic comorbidity of CAS and ASD is the wide differences in their reported prevalences, with idiopathic CAS estimated at approximately .1% (Shriberg & Kwiatkowski, 1994) and ASD reportedly at approximately 1% (Rice, 2009), a 10-fold increased risk. Unless a more highly prevalent subtype of CAS than the idiopathic form is posited for either or both nonverbal and verbal ASD, comorbid ASD and CAS would be expected to be extremely rare (i.e., 1/100,000, multiplying the individual probabilities of each disorder).

Phenotypic similarity
A third rationale is based on findings reviewed presently indicating that the speech, prosody, and voice characteristics of some children with low and high verbal ASD reportedly are similar to those found in children and adults with apraxia of speech. The validity of this claim for the CAS-ASD hypothesis, the most testable of the three rationales reviewed, requires close examination of the ASD-speech literature, in particular, findings for prosody and voice characteristics. A constraint, however, is that literature findings to date are heterogeneous and lack the conceptual organization needed for comparative analyses. Peppé, McCann, Gibbon, O’Hare, and Rutherford (2007) provide a useful perspective on the precedent speech literature in ASD:

In the research literature, numerous adjectives are used to describe atypical expressive prosody in autism, for example, dull, wooden, singsong, robotic, stilted, overprecise, and bizarre (Baltaxe & Simmons, 1985; Fay & Schuler, 1980); terms that perhaps reflect perceived characteristics of autism more than acoustic features. The fact that adjectives with opposite meanings, such as monotonous and exaggerated (Baron-Cohen & Staunton, 1994), can be used to describe this atypicality suggests a wide variation in either the perception of atypical expressive prosody or in the prosody itself. (p. 1016)

The following overview of idiopathic speech sound disorders attempts to redress this situation. The goal of this tutorial is to introduce terms and concepts needed for efficient review of the ASD-speech literature. The system described in the next section is also used later to organize findings from the present study.

A tutorial on Idiopathic Speech Sound Disorders (SSD)

The cover term Speech Sound Disorders (SSD) was adopted by the American Speech-Language-Hearing Association in 2005 to replace both the early 20th century term functional articulation disorders, and the term used for the same clinical entity from approximately 1980 to 2005, phonology disorders of unknown origin. There is no current professional consensus, however, on nomenclature for subtypes of SSD (i.e., excluding disorders of known origin, such as those due to cleft palate, Down syndrome, deafness, traumatic brain injury, or other frank cognitive, structural, sensory, motor or affective disorder). The nosology in Table 1, from a system termed the Speech Disorders Classification System (SDCS: Shriberg et al., 2010a), has evolved for genomic and other descriptive-explanatory research in SSD of currently unknown origin. As indicated, the speech classification terms and concepts in Table 1 are needed to organize both the literature review in Table 2 and findings from the present study. Technical information on perceptual and acoustic procedures used to classify participants’ speech status using the SDCS in a software environment is available elsewhere (Shriberg et al., 2010b; see also http://www.waisman.wisc.edu/phonology/).

Table 1
Table 1
Definitions and descriptive statistics for six subtypes of speech sound disorders in the Speech Disorders Classification System (SDCS).
Table 2
Table 2
Prevalence estimates and descriptive findings for subtypes of speech sound disorders in studies of speakers with verbal Autism Spectrum Disorders (ASD). Studies are ordered chronologically within each set of findings.
Speech Delay
Speech Delay (SD) is the SDCS classification term for 3 to 9 year-old children with mildly to severely reduced intelligibility due to age-inappropriate speech sound deletions, substitutions, and distortions. As indicated in Table 1, children with SD generally do not have notable impairments in prosody or voice, an important differential diagnostic sign between SD and CAS discussed below. Relative to typically-developing children, however, children with SD have higher rates of language impairment, lowered intelligibility, and are at greater risk for reading impairment. Two American English population estimates of speech sound disorders using similar definitions and methods (Campbell et al., 2003; Shriberg, Tomblin, & McSweeny, 1999) report approximately similar point prevalence population estimates (15.6%, 15.2%, respectively) at 3 years of age (interpolated finding in Shriberg et al., 1999) and similar estimates (3.8%) at 6 years of age. A third large British English epidemiological study, also using the SDCS definition of SD, reported a population estimate at 8 years of age of 3.8% (Wren, Roulstone, Miller, Emond, & Peters, 2009).

Speech Errors
Speech Errors (SE) is the SDCS term for 6 to 9 year-old children whose speech impairment is limited to distortions of one or two English sounds or sound classes: the sibilants /s/ and /z/ and the rhotic consonant /r/ and/or the stressed and unstressed rhotic vowels (as in “bird” and “sister,” respectively). Elementary-school American English children with SE are typically not provided speech services because, as shown in Table 1, SE is generally not associated with prosody-voice impairment, language disorder, or intelligibility deficits and children with SE are not at risk for reading impairment (Shriberg, 2010b; Wren et al., 2009). Using definitions and methods for SE classification adapted from the SDCS, the Wren et al. (2009) epidemiologic study reported a point prevalence of SE at 8 years of age of 7.9%.

Persistent Speech Disorders (PSD)
Persistent Speech Disorder (PSD) is the SDCS term for speech disorders that persist past 9 years of age and for some speakers, for a lifetime. By 9 years of age, most children with histories of either SD or SE have normalized speech production, but a percentage of adolescents and adults continue to misarticulate. Children with prior SD may continue to have speech sound deletions, substitutions, and/or distortions, and children with prior SE may have persistent sibilant and/or rhotic distortions. As shown in Table 1, depending on whether such speakers have histories of SD or SE, they also may have persistent impairments in language, intelligibility, and/or reading. Flipsen’s (1999) review of survey and epidemiology studies, which also used the SD and SE classification constructs to organize the literature, yielded an estimated prevalence rate for PSD of 2.4%–3.9%.

Motor Speech Disorder (MSD)
The fourth classification entity for speakers with idiopathic SSD, Motor Speech Disorder (MSD), includes speakers of all ages whose significant intelligibility deficits are associated with motor speech impairment. As shown in Table 1, MSD subsumes three subclassifications. MSD-Apraxia of Speech (MSD-AOS) is the same clinical entity as Childhood Apraxia of Speech (CAS), a term that the American Speech-Language-Hearing Association adopted in 2007 to replace the prior terms Developmental Apraxia of Speech and Developmental Verbal Dyspraxia (the latter term continues to be used in medical contexts and in most other countries). As indicated previously, CAS will be the reference term for this classification in the present paper.

The core feature of both congenital and acquired apraxia of speech is a deficit in the planning/programming processes that transcode linguistic representations to the articulatory movements for speech. Motor Speech Disorder-Dysarthria (MSD-DYS), the second subclassification of MSD, is itself, a cover term for several subtypes of neuromuscular deficits (e.g., spastic dysarthria, ataxic dysarthria, hyperkinetic dysarthria) in the production of speech sounds (Duffy, 2005). Motor Speech Disorder-Not Otherwise Specified (MSD-NOS) is a recently proposed classification entity (Shriberg et al., 2010a) for speech signs that are not specific for apraxia or dysarthria and for speakers who have signs of motor speech involvement, but do not meet inclusionary criteria for either CAS (i.e., MSD-AOS) or MSD-DYS.

As indicated in Table 1, each of the three MSD classifications is characterized by deletions, substitutions, and distortions of sounds. Unlike SD, SE, and PSD, however, each MSD classification is also characterized by significant and persistent deficits in prosody and voice features. Speakers with MSD likely have concomitant language disorder, typically have significant intelligibility deficits, and generally are at increased risk for reading impairment. As cited previously, based on clinical referrals to one University speech clinic in a moderate-sized city, a preliminary estimate placed the population prevalence of CAS at .1% (Shriberg & Kwiatkowski, 1994). Several published and unpublished sources internationally indicate false positive rates for CAS of 80 to 90%, reflecting the lack of consensus on the inclusionary and exclusionary criteria for this disorder, especially as suspected in toddlers, preschool, and early elementary age children. There are no available prevalence estimates for MSD-DYS or MSD-NOS, although many researchers suggest that subclinical dysarthria and delays in maturation of sensorimotor systems subserving speech (i.e., MSD-NOS) may account for a substantial proportion of idiopathic speech sound disorders.

Prevalence Estimates and Speech, Prosody, and Voice Findings in Verbal ASD

The considerable body of research on the language characteristics of speakers with ASD (see Smith, 2007; Tager-Flusberg, 2009; Tager-Flusberg, Paul, & Lord, 2005 for reviews) has reported extensive heterogeneity of expressive ability among children with verbal ASD, ranging from children with only single word or simple word combinations to children with precocious levels of vocabulary and sentence structure. Tager-Flusberg and Joseph (2003) have proposed a system for classifying subtypes of language development within speakers with ASD, with other investigators raising validity issues about the system (e.g., Eigsti, Bennetto, & Dadlani, 2007; Whitehouse, Barry, & Bishop, 2007).

In contrast to the widespread intense interest in the language abilities of children with ASD, few studies have focused on the speech abilities of children, adolescents, and adults with ASD. Table 2 includes a summary of prevalence estimates for subtypes of speech sound disorders and speech, prosody, and voice impairment findings in speakers with verbal ASD. The entries in Table 2 do not include questionnaire data or single case study observations. Only information on productive speech, prosody, and voice behaviors is included, not studies of speech perception or comprehension in ASD; for reviews of the latter domains see Diehl, Bennetto, Watson, Gunlogson, and McDonough (2008); Diehl, Watson, Bennetto, McDonough, and Gunlogson (2009); McCann and Peppé (2003); and Paul, Augustyn, Klin, and Volkmar (2005). The format and content in Table 2 is the first to organize prevalence and descriptive findings using the SDCS classifications described in Table 1.

As shown in the top section of Table 2, three studies have estimated the prevalence of subtypes of speech impairment in ASD, each using definitions of one or more subtypes of speech impairment consistent with the subtypes in Table 1. Impairment consistent with Speech Delay (SD) occurred in 12% of the 3 to 9 year-old children with ASD studied by Cleland, Gibbon, Peppé, O’Hare, and Rutherford (2010). Rapin, Dunn, Allen, Stevens, and Fein (2009) reported SD and Speech Errors (SE) in 24% of participants with ASD during this age period. Cleland et al. also reported that 33% of the children with ASD studied had either SE or Persistent Speech Disorder (PSD). Shriberg, Paul, et al. (2001) reported that 33% of adolescents and adult study participants had PSD. Thus, although each of the subtypes of speech impairment in Table 1 have been reported in ASD, few between-study comparisons are possible due to differences in the age groups studied. Among the 11 studies in Table 2 in which the data could be interpreted as absence of support or support for SD in ASD (indicated by “X”), four have reported absence of support for SD and seven have reported support for SD in ASD. Velleman et al. (2010) is the only study series to date supporting speech impairment consistent with the SDCS term Motor Speech Disorder-Not Otherwise Specified. Although frank CAS was not observed in their studies, the findings Velleman and colleagues report using an array of perceptual and acoustic indices are consistent with MSD-NOS.

The remaining entries in Table 2 organize findings in the ASD literature using the Prosody (Phrasing, Rate, Stress) and Voice (Pitch, Loudness, Laryngeal Quality, Resonance) domains in the SDCS. The most well-studied prosody domain is Stress, with the 16 studies in Table 2 reporting impairments in participants’ with ASD ability to produce correct contrastive, emphatic, sentential, syntactic, and syllable stress (for reviews, see McCann & Peppé, 2003; McCann, Peppé, Gibbon, O’Hare, & Rutherford, 2008; Paul, Augustyn, et al., 2005; Paul, Bianchi, Augustyn, Klin, & Volkmar, 2008; Peppé et al., 2007). As shown in Table 2, impairments have been reported in at least one published study of ASD for each of the other 6 prosody and voice domains.

Go to:
Statement of Purpose
The primary goal of the present study was to assess the weak version of the CAS-ASD hypothesis—the hypothesis that concomitant CAS may be a sufficient causal explanation for at least some of the speech, prosody, and voice impairments reported in ASD. A secondary goal of the study was to estimate in a sample of verbal young children with ASD the prevalence of the two primary forms of speech impairment of unknown origin: Speech Delay and Speech Errors.

Tesla_WTC_Solution
31st March 2014, 16:01
I wanted to point out that two conditions common to autism, Apraxia of Speech and Spatial Neglect, are directly linked in many cases with the advent of stroke.
I was shocked to find this out yesterday.


I guess TED already asked this in 2012:
http://www.ted.com/conversations/12552/could_autism_be_caused_by_a_mi.html
Could autism be caused by a mild stroke while in the womb or during infancy?

Doctors have tried to talk about it: http://www.vaccineriskawareness.com/Doctor-Says-Vaccines-Cause-Micro-Vascular-Strokes-In-Babies-and-Children


Doctor Says Vaccines Cause Micro Vascular Strokes In Babies and Children

Dr. Andrew Moulden, from Canada, has been a practising physician for 21 years. He and other doctors have completed research that has proved a causal link between vaccination and micro vascular strokes. He presented his research to various medical journals and organisations, but none would review it, publish it or comment on his research.

Frustrated, and wanting parents to know about this important research, Dr. Moulden decided to get involved in government and see if he could change the system from the inside.

Here's what he discovered about vaccines:

Dr. Moulden says the shots cause our body's own immune systems to hyper-react as large white blood cells naturally rush to attack the foreign particles injected into our bloodstream. The white blood cells are too big to enter, so they surround tiny capillaries where the foreign particles land, clog and collapse the capillaries.

This cuts off pathways for the smaller red blood cells to carry oxygen to the organs near those capillaries that contain the foreign particles. When the particles float near the brain, this lack of blood supply can lead to autism, SIDS and many other diagnosed illnesses in both children and adults.

Our immune systems will continue fighting the particles leading to long-term or chronic illness. Different organs are affected depending on where the particles are, which leads to different symptoms and 'disease' names, but the basic causes are the same and before this discovery were unknown.

The main cause of the problem is the additives in the vaccines. The purpose of the additives is to generate a faster response from white blood cells. This works perfectly - white blood cells rush to the site of the introduced foreign matter - and that is the source of the problem. The white blood cells block the capillaries and also collapse them, trying to destroy the foreign matter.

Dr. Moulden has been appointed to the Scientific Advisory Board for the First Annual World Congress on Vaccinology in Guangzhou, China, December 1- 5, 2008, where, he is to present to a group of 10,000 experts from around the world.

(From NewsBlaze, by Alan Gray, 27 September 2008).

To contact Dr. Andrew Moulden, see his political website, www.justgetusin.com or call him on (705) 498-6284.
VAERS Report of Stroke after Vaccination

A 1 year old boy was given DTaP, IPV and PNC vaccines.

Vaccines were given on 10/7/03 pm child developed fever next day and increased sleepiness. Mother called PMD's office at night of 10/8/03 and was given fever monitoring, testing instructions. Next time parent called on 10/12/03. Mother was informing us that pt was not moving a lot and had weakness of his L arm. Pt was taken to hospital ER and diagnosed with L hemiparesis. MRI of the head revealed R middle cerebral arthey ischemic stroke. He was admitted to the hospital inpatient floor. Extensive blood work up was done including coagulation studies, protein C, S, factor V Leida was negative. Etiology of this event is unclear. Child was started on anticoagulants during hospital stay. Currently is on no medications. The hospital records received on 3/23/04 states stroke.

Case number: 211555

Tesla_WTC_Solution
31st March 2014, 16:49
(I got more interested in stroke etc. when I realized I had vasculitis symptoms, and it's an autoimmune disorder to boot)

(I've often wondered if ASD kids have strokes and why the Drs only medicate the symptoms and not treat the underlying cause)

Tesla_WTC_Solution
5th April 2014, 18:01
Chili's Is Fundraising For A Notoriously Anti-Vaccine Charity

Paul Szoldra, provided by
http://imgs.sfgate.com/graphics/partners/businessinsider/article_header.gif

Published 8:17 pm, Thursday, April 3, 2014

In honor of National Autism Awareness Month, Chili's is planning to donate 10% of customers' checks on April 7 to the National Autism Association, a charity with controversial views about vaccinations.

More than 1,200 Chili's restaurants will participate in the fundraiser for the group, which writes vaccinations can trigger or exacerbate autism in "some, if not many, children" on its website.

...

NAA dodges a direct yes or no position about vaccines on its website FAQ, writing that it "cannot make this decision for any parent, but we are happy to provide sources of information to anyone in need. We recommend visiting http://nvic.org."

That link goes to the National Vaccine Information Center, which journalist Michael Specter characterizes in his book "Denialism" as " ... an organization that, based on its name, certainly sounds like a federal agency. Actually, it's just the opposite: The NVIC is the most powerful anti-vaccine organization in America, and its relationship with the U.S. government consists almost entirely of opposing federal efforts aimed at vaccinating children."

Further, NAA sponsors "Age of Autism," a website which has the text "Yes, Vaccines Cause Autism" on its masthead.

____________________________

Tesla_WTC_Solution
7th April 2014, 21:02
I am having an argument in my Autism Support Group with a lady who is pro vaccine.
it's really annoying. I've told her all kinds of **** and she is like DENY DENY

i even told her about military, and just DENY DENY

Fn B lol

Tesla_WTC_Solution
8th April 2014, 00:55
There is now a nurse in the pro-vaccine debate, and she has called names in the argument, such as "fringe", and she uses the word "anecdotal" constantly.

I ripped her a freaking new one, without actually getting mad, I put on my methodical Tesla hat for once and cleaned her house for her.

:)

I said asking a nurse about vaccine injury is like asking the police dept for info on police brutality. and she got super pissed.

Hervé
8th April 2014, 18:41
Gardasil: Child Abuse by Big Pharma (http://www.townsendletter.com/FebMarch2014/gardasil0214.html)

by Gary Null, PhD, and Nancy Ashley
http://www.townsendletter.com/Images/transparent.gif

http://www.townsendletter.com/Images/transparent.gif
From the Townsend Letter February/March 2014 (http://www.townsendletter.com/FebMarch2014/FebMarch2014.html)

Page 1, 2 (http://www.townsendletter.com/FebMarch2014/gardasil0214_2.html)
Gardasil, the human papilloma­virus vaccine produced by Merck, was brought to market in 2006 with great fanfare, widely proclaimed as the first ever anticancer vaccine. Having gained a strong foothold due to fast-tracking by the FDA and rushed to market ahead of completed safety studies and ahead of its competitor, Gardasil was already an entrenched, recommended vaccine by the time it was approved.1 Merck created a market for Gardasil out of thin air with deceptive and dishonest advertising, and thereby planted fear in the mind of consumers: fear of an unknown health crisis, an invisible time bomb waiting to explode and harm women everywhere.2 When criticized for its aggressive marketing, Merck countered that it was performing a public service by raising awareness about the human papillomavirus and wasn't selling anything.3 Really? This lie became public as Merck was caught lobbying the 50 states for mandatory Gardasil vaccination prior to FDA approval.4 The fact is that there was never a need for Gardasil in the first place: regular Pap testing had already lowered the incidence of cervical cancer by 80% in the US to a few thousand cases a year, and the vast majority of all HPV infections resolve of their own accord.5 But by lining the coffers of such groups as Women in Government (WIG), National Foundation for Women Legislators (NFWL), National Conference of State Legislatures (NCSL), and, of course, the American Legislative Exchange Council (ALEC), Merck was able to influence legislation such that almost immediately after the vaccine was approved, it was part of the vaccine schedule recommended for all girls.6 If it hadn't been for Governor Rick Perry's blatantly self-serving blunder of trying to mandate Gardasil for school attendance in Texas in the face of huge conflict of interest and a $50 million contribution to his presidential campaign, Gardasil might have gone even further.7

There is something deeply wrong with a giant pharmaceutical company spending hundreds of millions of dollars to manipulate women and influence legislation in order to generate a revenue stream of billions of dollars a year for itself at the expense of a gullible public. Because what is wrong with Gardasil isn't just that it is unnecessary. Gardasil is possibly the most dangerous vaccine on the market, with the potential to injure, maim, or even kill the children who receive it. The program of coercion to vaccinate every 11- to 26-year-old girl with Gardasil is relentless. This vaccine is given not just in doctor's offices, where doctors have been known to "fire" noncompliant patients, but in schools and colleges, where the pressure on girls and their parents to conform can be extreme. These institutions all have quotas – sometimes including financial rewards – and they are anxious to prove high rates of compliance.8 But there is no informed consent prior to vaccination, so most of these girls and their parents have no idea what they are risking by agreeing to vaccination with Gardasil. While Merck, the FDA, the CDC and the medical establishment all deny that there have been serious, life-altering adverse events associated with Gardasil, the fact is that compared with the mandated vaccines which are given with greater frequency, Gardasil still has the most adverse events reported to the Vaccine Adverse Event Reporting System (VAERS) of any vaccine. And since reporting of adverse events is not mandatory in the US (although outbreaks of so-called vaccine-preventable illness are), it is likely that only 10% even get reported!9

And what of the victims of Merck's war on cervical cancer? Alexis Wolf was a normal seventh-grader in 2007. She had type 1 diabetes, but had successfully learned how to give herself insulin shots and eventually graduated to an insulin pump, which she also mastered easily. Alexis made the honor roll for the first time that year, and was rewarded with a trip to Germany over the summer to visit her grandparents. Her endocrinologist believed that the diabetes was under control and thought that Alexis would be perfectly capable of making the trip on her own and managing her diabetes herself. To make sure everything was in order prior to travel, Alexis' doctor recommended that she receive her first Gardasil vaccine.

The trip went well, but Alexis seemed different to her mother when she returned, perhaps a bit distant. Alexis received her second Gardasil vaccine after coming home, and shortly thereafter her personality changed entirely. For a relatively shy girl, Alexis immediately became very gregarious, hugging everyone all the time. But she also became agitated and troubled, and started having difficulty keeping food down. It reached the point where she threw up a number of times a day, which is especially dangerous for a diabetic. There began a series of appointments with many, many doctors: the GP, the endocrinologist, the cardiologist, the gastroenterologist, and numerous different diagnostic tests. But nothing they did or recommended seemed to help. Alexis was struggling to get through her days, usually carrying a bucket with her at all times just in case. She had terrible insomnia, was eating excessively, and was falling further and further behind in school.

In January 2008, Alexis received her third Gardasil shot – within 2 weeks she was in the hospital. Her behavior had worsened to the point where she was considered bipolar and she was put on a series of antipsychotic medications. Her mother didn't believe that this was a psychological problem. She knew that something else had to be wrong, knew that there had to be some medical explanation for what was going on. After weeks and months in and out of different hospitals with no improvement and her condition growing more desperate, Alexis at long last was seen by a doctor who recognized that she was having seizures – something that all the previous doctors had overlooked. This led to more tests – EEGs, MRI imaging, and spinal taps – and finally a conclusion that seemed to make sense: encephalitis, traumatic brain injury, and seizure disorder. But why? Alexis's mother had an additional conclusion which was so crystal clear in hindsight – her daughter was normal before she received the Gardasil vaccine and had worsened with each one. The Gardasil vaccine had left Alexis with brain damage.

We spoke with Tracy Wolf, Alexis's mother, about their ordeal. While maintaining a cheerful optimism, Tracy admitted that she could never have foreseen how their lives would change completely. After Alexis's seizure disorder was identified and she was put on antiseizure medication, her physical symptoms improved to a certain extent, but she was completely altered. Alexis has deteriorated from being a normal child to one who is only functioning at a fourth-grade level. Forced to enter special education instead of rejoining her previous class, Alexis became enormously frustrated and school became an ordeal for everyone. When Alexis turned 18, Tracy finally gave up and pulled her out of school, realizing that it really could not offer Alexis anything but misery. The stress on their family has been enormous. The pressure caused the Wolfs' marriage to dissolve, and Tracy is now raising both daughters by herself, with their father living in a different state. Alexis needs almost constant supervision, and Tracy can only leave her alone for short periods of time. They have applied for special services that could possibly be helpful, but the waiting list is long. Alexis doesn't understand why things are so different, why her little sister is learning to drive but she can't.10

Unlike with other types of injuries, a vaccine victim cannot simply sue the company responsible for the problem. Since 1986, all cases of vaccine injury must be brought to the Office of Special Masters at the US Court of Federal Claims, commonly called the vaccine court. This court was established to create a nonadversarial situation in which children injured by vaccines could receive compensation. But the Department of Health and Human Services has completely distorted the intent of this legislation, and turned it into a highly adversarial proceeding. Injuries listed on a table are supposed to be automatically compensated, but a lot of injuries have been removed from the table over the years, and new vaccines, such as Gardasil, are listed with no specific injuries attributable to them. So the burden is on the victim to prove causation because there is no presumption of any injury.

In conversation with William Ronan, a lawyer retained by Alexis's family, he shared that his law firm currently is handling 12 to 15 Gardasil cases that are being evaluated and another 6 cases already filed in the vaccine court. Interestingly, out of all the types of Gardasil-related injuries, the cases that Ronan represents all fall into two main categories: autoimmune and neurological. When the injuries are neurological, doctors frequently can't put their finger on what is wrong, and end up sending the girls to a psychiatrist. Ronan maintains that it is impossible for all of these girls suddenly to have developed mental problems or simply to be imagining that they have been harmed since receiving the Gardasil vaccine. While not antivaccine himself, he has seen too many girls have serious adverse reactions to Gardasil. He runs a two-person law firm in Kansas City, and without advertising, has received at least 20 to 30 calls regarding Gardasil injuries. Ronan believes that his experience is just the tip of the iceberg – anyone actually advertising legal services for Gardasil victims would be inundated with a huge number of cases.

The work is slow going. Evidence of harm caused by vaccines is crucial, but there aren't a lot of published medical studies about safety to back up this claim. Those that exist are funded by the manufacturer and tend to be overly favorable. Possibly the strongest argument against Merck, according to Ronan, is its failure to warn girls of the risk involved when getting the Gardasil vaccine. Merck clearly knew that this drug could cause neurological dysfunction, yet did not adequately address this in the product insert. Also, it is well known that girls who already have an HPV infection are more likely to be harmed by the vaccine, but the manufacture does not make this clear and does not recommend testing. Ronan summed up his view of vaccinating young girls with Gardasil:
The real issue is: what is the benefit of this vaccine? Do the benefits outweigh the risks? There is a risk of a seizure disorder or an autoimmune disorder versus the benefit that it might reduce cervical cancer. But Gardasil doesn't eliminate the need for regular Pap testing, which is already safe, and there isn't good evidence that it prevents cervical cancer. In evaluating risk and benefit, when all the facts are known it becomes a pretty easy decision – the vaccine is more dangerous than any benefit. Unfortunately, medical professionals tend to read and listen to information provided by the manufacturers, which doesn't adequately present the risks involved, so they actually aren't sufficiently informed to advise their patients.
Ronan's own daughter had to fight off an aggressive attempt by her doctor to get the Gardasil vaccine, so he understands the pressure that girls are under to just go along instead of asking questions.11

We interviewed Dr. Meryl Nass, board-certified internal medicine practitioner and vaccine specialist, who agrees that Gardasil was rushed to market without adequate safety testing. Three years after approval for girls, the company likewise received approval to vaccinate boys age 9 and above with no new studies and very little data to justify this action. Regarding Gardasil's adverse effects, Nass said:
Children don't usually die suddenly when they are healthy but there are certainly lots of teenage girls who have died elatively suddenly after Gardasil or developed severe neurologic reactions. Therefore, if you are going to try to balance safety and efficacy when you prescribe something like a vaccine, you have to know how effective it's going to be. Does this really prevent cervical cancer in young women? And does it prevent it in women who have already been exposed to these viruses? … So I don't know how other doctors prescribe something like Gardasil … Basically, they make an assumption that since the FDA has licensed it … the manufacturer would only market something that's safe, doctors go ahead and prescribe. And what they may not be aware of is that it is extremely hard to link a side effect to a vaccine, for many reasons. Getting a judgment against a manufacturer is very difficult and it has become more difficult due to some recent litigation that reduced manufacturer liability for vaccines in general.12
Gardasil's doctrine is already so entrenched after only six years that it is a formidable task to challenge the official story that this vaccine is safe and effective, because the truth is too unsettling. The remarkable claims of Gardasil's benefits to women in the war on cancer are full of holes and not supported by the science, even that science funded by Merck itself. It is important to deconstruct the falsehoods and half-truths that masquerade as facts about Gardasil.

[...]

Full article: http://www.townsendletter.com/FebMarch2014/gardasil0214.html

Tesla_WTC_Solution
8th April 2014, 21:02
Amzer Zo, thank you, I forgot about the Gardasil, that should be all the evidence people need, but they still believe lies.

I had two women in there thank me for trying to tell what they believe is the truth.
I tried to be real fair and honest, pointed out what's insane etc. about public beliefs and the law.

And pointed out that doctors and nurses are trained to ADMINISTER a vaccine but can't explain how they work.
I asked also whose fault it was that doctors didn't notice that our kids were being overdosed on Tylenol in 2005-2010.
I said "if you didn't notice something like that you wouldn't notice something like vaccine injury either".

The nurse mentioned Rotavirus as being the only dangerous one she'd heard about, and I was like, Wow, that's the one they gave my son, on the wrong date.

:(

Tesla_WTC_Solution
9th April 2014, 18:43
Is anyone else on the ASD spectrum or with GWS having issues with liver pain the day after heavy exercise?

I hiked 5 hours yesterday, and this morning while walking on flat road, my liver started hurting so bad, for a minute or two.
I ignored it and it went away.

Very concerned about stress disorder.

Tesla_WTC_Solution
10th April 2014, 00:54
p.s. i figured it out, i think

this pain is probably normal for anyone with NAFLD, which is a serious disease but treatable by exercising.

apparently good exercise helps the body produce liver enzymes n stuff, who would have guessed???

(non alcoholic fatty liver disease -- strikes anyone who eats corn or is prone to diabetes)

Tesla_WTC_Solution
12th April 2014, 23:20
YOu guys would not believe the hostile bitches in the email group.

They got their panties in a wad because a few of us were outraged that Chili's restaurant cancelled the charity event with NAA (national autism association) because of the organization's open-mindedness toward vaccine injury awareness.

i have asked to be unsubscribed from that email group.
they are horrible. lol

Fairy Friend
12th April 2014, 23:47
you keep fighting I am convinced that these vaccinations are what took my grandson down and the doctor was a vaccine nut gave him more than he should have actually needed because he was on the line and being late in the vaccines because we held off. But she convinced my daughter that he would not be allowed in school if she did not do that and manipulated her and my son in law. A real bully.
My grandson took a little nose dive a while back he had an ear infection and they had to give him antibiotics. And we noticed a decline, a regression. Instead of direct eye contact he started glancing and not direct eye contact, his fine motor skills went down a little and words suddenly disappeared again where he would say dog ruff ruff now he would wait for you to say dog and just say woof. And not name the animal but say what the animal says. But we do the best we can right?

Tesla_WTC_Solution
13th April 2014, 01:10
you keep fighting I am convinced that these vaccinations are what took my grandson down and the doctor was a vaccine nut gave him more than he should have actually needed because he was on the line and being late in the vaccines because we held off. But she convinced my daughter that he would not be allowed in school if she did not do that and manipulated her and my son in law. A real bully.
My grandson took a little nose dive a while back he had an ear infection and they had to give him antibiotics. And we noticed a decline, a regression. Instead of direct eye contact he started glancing and not direct eye contact, his fine motor skills went down a little and words suddenly disappeared again where he would say dog ruff ruff now he would wait for you to say dog and just say woof. And not name the animal but say what the animal says. But we do the best we can right?

thanks for this.
although it's heartbreaking, i like it when people are honest and detailed.
i hope you guys see improvement.

my guy has a lot of trouble forming words.
i can tell he is thinking of something complicated but the words just get stuck.

not sure if it's physical or related to self confidence/mental health or what.

i feel horrible. :(

Fairy Friend
13th April 2014, 05:04
I am starting to wish that I had a lot and a lot of money. I could spend 100 million dollars and I would start a foundation that ran a battery of tests on these kids. From top to bottom starting with non invasive of course and most likely to be true. Instead of thinking around with all this crap nonsense.

Tesla_WTC_Solution
13th April 2014, 14:12
I am starting to wish that I had a lot and a lot of money. I could spend 100 million dollars and I would start a foundation that ran a battery of tests on these kids. From top to bottom starting with non invasive of course and most likely to be true. Instead of thinking around with all this crap nonsense.

Thank God for people like you guys!

The AutismKing group I am leaving, it's like a zombie army of yuppie b*tches who live to report you on their cell phone.

I would love a change, even in fantasy land, lol

Agape
13th April 2014, 15:02
Hi Tesla .. just a small point .. it's observational point , I'd have to search for references and how many studies have been done on the topic and what were the results ..autism and allergies ..

It's not going to heal the genetic causes but avoidance of allergens can alleviate many severe reactions , physical and mental, just when you are uncertain of any immediate cause .
One basic problem with our 'instinctive brain' ( the limbic cortex ) when in stress or evolution ( both are stress ) is the way it reacts to sensory stimuli and pain receptor metabolites - the whole chain of small irritating disturbances that are happening everywhere around you though no where in particular .

Much has been discussed about food allergens and balanced non-chemical diet , from your own experience you may also know and find out how some seemingly innocent ( non harmful ) products , whether they're plant or animal origin can cause disturbing reaction and it can be determined only individually what each particular person finds difficult to handle .
Though own tastes and wastes seem to offer good guidance and I don't believe in forcing people ( especially not children ) to foods they dislike just because they're labeled 'healthy' .

From non food allergies my point is this ...

try to avoid woollen cloth , if possible all of them ..if not, they should be used over cotton shirts , avoid direct skin exposure to them over long time.

The only healthy wearables in fact is either pure organic cotton ( it does not have to be bought and sold under that label, there is plenty of pure organic cotton from China that is cheap and still of high quality ) or silk, pure silk has some amazing and almost miraculous healing properties and is cooling and calming for the system ( it tends to be expensive in the west but it can be found now n then in off sale ) .

and then I'd advice to be careful with artificial materials and fabrics , and mixtures, it really depends .
There are some modern ultra light materials that let the air through and are non allergenic , happy and healthy but plenty of the old polyesters and what's in the cloth shops till now is not .

Beware of feathers .. unless they undergo thorough cleansing process, they tend to hosts parasites . Feather duvets are out of use these days but they're still not exception .

I'd not advice even hemp or other coarse materials, especially for a kid , even if they're labeled healthy , they're still irritating .

On top of that , use the 'baby cloth washing liquid' for soft fabrics , and wash them just often as possible . If you feel they've been sweated they should be changed asap .


Long time exposure ( hours at times ) to anything that causes allergy and irritation makes the kids ( even adults but children are more sensitive and often find hard to determine the cause even for themselves ) very nerd , and remember the way they react to touches and physical contact , it's one of the most sensitive gates to the body .


:panda:

Tesla_WTC_Solution
13th April 2014, 15:34
Thanks for this. Very good advice.

My sister has a metal allergy and a bee sting allergy, for example.

I hated wool as a kid and had severe asthma.

Agape you are 100% right.

Hervé
20th April 2014, 13:27
I haven't seen it, but it has a 100% on both Rotten Tomatoes (https://en.wikipedia.org/wiki/Rotten_Tomatoes) (based on 11 reviews) and Metacritic (https://en.wikipedia.org/wiki/Metacritic) (based on 4 reviews) ratings...

Best Kept Secret (film) (https://en.wikipedia.org/wiki/Best_Kept_Secret_%28film%29)
From Wikipedia, the free encyclopedia

Best Kept Secret
https://upload.wikimedia.org/wikipedia/en/thumb/2/2d/BestKeptSecretPoster.jpg/220px-BestKeptSecretPoster.jpg (https://en.wikipedia.org/wiki/File:BestKeptSecretPoster.jpg)
Directed by Samantha Buck (https://en.wikipedia.org/wiki/Samantha_Buck)
Produced by Danielle Di Giacomo
Music by Brian Satz
Cinematography Nara Garber
Editing by Francisco Bello, Matt Posorske
Release dates: May 4, 2013
Running time 85 minutes
Country United States
Language English

Best Kept Secret is a 2013 documentary film that was directed by Samantha Buck (https://en.wikipedia.org/wiki/Samantha_Buck) and produced by Danielle DiGiacomo[1] (https://en.wikipedia.org/wiki/Best_Kept_Secret_%28film%29#cite_note-1). The film aired as part of POV (https://en.wikipedia.org/wiki/POV_%28TV_series%29) on PBS (https://en.wikipedia.org/wiki/PBS) and focuses on a special education (https://en.wikipedia.org/wiki/Special_education) teacher who must find her students a place in the real world as they prepare to leave the public school system.

Tesla_WTC_Solution
20th April 2014, 18:29
That looks worth watching!!!

nQYuT69gAH4

http://www.pbs.org/pov/bestkeptsecret/


Synopsis

At a public school in Newark, N.J., the staff answers the phone by saying, "You've reached John F. Kennedy High School, Newark's best-kept secret." JFK provides an exceptional environment for students with special-education needs. In Best Kept Secret, Janet Mino, who has taught a class of young men for four years, is on an urgent mission. She races against the clock as graduation approaches for her severely autistic minority students. Once they graduate and leave the security of this nurturing place, their options for living independently will be few. Mino must help them find the means to support themselves before they "age out" of the system. (90 minutes)

Hervé
24th April 2014, 14:40
FDA Document Reports Autism Link After Tetanus, Pertussis & Diptheria Combination Vaccine (http://www.collective-evolution.com/2014/04/09/fda-document-reports-autism-link-after-tetanus-pertussis-diptheria-combination-vaccine/)

April 9, 2014 by Arjun Walia (http://www.collective-evolution.com/author/arjun/). 24 Comments. (http://www.collective-evolution.com/2014/04/09/fda-document-reports-autism-link-after-tetanus-pertussis-diptheria-combination-vaccine/#comments)
https://www.google.com/images/cleardot.gif


http://cdn3.collective-evolution.com/assets/uploads/2014/04/tripedia-300x224.jpeg


An FDA report from 2005 titled “Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed Tripedia” outlines a number of adverse events reported during post-approval use of the Tripedia vaccine, and one of them is autism. (1) (http://www.fda.gov/downloads/biologicsbloodvaccines/vaccines/approvedproducts/ucm101580.pdf)

Health-care providers who administer vaccines are required to keep permanent vaccination records, they are also required to report any occurrences (adverse events such as autism) to the Secretary of the US Department of Health and Human Services following immunization of any events.

The report also illustrates that the tripedia vaccine has not been evaluated for its carcinogenic or mutagenic potentials or impairment of fertility. This makes one wonder what other vaccines have not been properly evaluated. Furthermore, it illustrates how a review by the Institute of Medicine (IOM) found evidence for a causal relationship between tetanus toxoid and both brachial neuritis and Guillain-Barre syndrome.

This document just adds more confusion to the topic of vaccines and autism. How can the general public be expected to believe there is no link when more evidence keeps on mounting that suggests that there could be. Why does an FDA document even mention autism and its association with vaccinations?

There is good reason to be confused, this isn’t fear mongering.

For example, a recently published study in the peer-reviewed journal Translational Neurodegeneration provided epidemiological evidence supporting an association between increasing organic-Hg exposure from thimerosal-containing childhood vaccines and the risk of ASD diagnosis. (2) (http://www.ncbi.nlm.nih.gov/pubmed/24354891)

On the other hand, a study published in March of 2013 determined that “Increasing exposure to Antibody-Stimulating Proteins and Polysaccharides (antigens) in Vaccines is Not Associated with Risk of Autism.” You can view that study here. (http://jpeds.com/webfiles/images/journals/ympd/JPEDSDeStefano.pdf)

Back the other way, there are a number of court cases where families have been compensated for vaccine related injuries. Courts have ruled (in multiple cases) that vaccines did indeed cause autism. How could a court of law rule this to be so if there is no scientific link (as claimed by governing health authorities) between vaccines and autism? Courts have compensated over 80 families linking vaccines to autism. Here (http://www.huffingtonpost.com/david-kirby/post2468343_b_2468343.html)is one example, you can learn more about that process by watching this (http://www.youtube.com/watch?v=xv_IaLHwgAQ)video.

I think it’s important to keep an open mind with regards to health authorities covering up information involving the risks associated with vaccines. Proof is already in the public domain. Researchers at the University of British Colombia have uncovered evidence showing that health authorities, pharmaceutical companies and vaccine manufactures have known about the dangers associated with multiple vaccines, but have withheld them from public knowledge in order to maintain “herd immunity.” (3) (http://nsnbc.me/wp-content/uploads/2013/05/BSEM-2011.pdf)

There have also been reports that the CDC has been hiding data showing that mercury in vaccines is linked to autism, you can read more about that here. (http://www.collective-evolution.com/2014/02/28/cdc-caught-hiding-data-showing-mercury-in-vaccines-is-linked-to-autism/)

The link between vaccines and autism is still speculative. With all the information available in the public domain, I do not see how anybody can say with certainty that there is no possibility of a link. The studies below demonstrate that this has been the subject of rigorous investigation by researchers all over the world, and the investigations continue until this day.

Sure, there are doctors that support and trust vaccinations, but just as valid are the arguments of those that don’t support them. They should not be ignored. The point I’m trying to make is that there is no definite answer, that the debate has not been settled as so many governing health authorities claim it to be.


efto1LpWkKw


Besides the vaccine autism controversy, vaccines have been linked to a number of other health ailments,

A paper published in the peer reviewed International Journal of Environmental Research and Public Health titledThimerosal Exposure and the Role of Sulfation Chemistry and Thiol Availability in Autism (http://www.mdpi.com/1660-4601/10/8/3771) concluded:

“With the rate of children diagnosed with an ASD in the US now exceeding 1 in 50 children and the rate of children with neurodevelopment/behavioural disorders in the US now exceeding 1 in 6 children, and the preceding evidence showing that there is vulnerability to ™ that would not be known without extensive testing, the preponderance of the evidence indicates that ™ should be removed from all vaccines”

A paper published in the Journal of Toxicology titled B-Lymphocytes from a population of Children with Autism Spectrum Disorder and Their Unaffected Siblings Exhibit Hypersensitivity to Thimerosal (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697751/) clearly demonstrates that certain individuals with a mild mitochondrial defect may be highly susceptible to mitochondrial specific toxins like thimerosal.

A study published in the Journal Annals of Epidemiology (http://www.ncbi.nlm.nih.gov/pubmed/21058170) has shown that giving the Hepatitis B vaccine to newborn baby boys could triple the risk of developing an autism spectrum disorder compared to boys who were not vaccinated as neonates. The research was conducted at Stony Brook University Medical Centre, NY.

A study published in the (http://omsj.org/reports/tomljenovic%202011.pdf)Journal of Inorganic Biochemistry (http://omsj.org/reports/tomljenovic%202011.pdf) by researchers at the Neural Dynamics Group, Department of Ophthalmology and Visual Sciences at the University of British Columbia determined that Aluminum, a highly neurotoxic metal and the most commonly used vaccine adjuvant may be a significant contributing factor to the rising prevalence of ASD in the Western World. They showed that the correlation between ASD prevalence and the Aluminum adjuvant exposure appears to be the highest at 3-4 months of age. The studies also show that children from countries with the highest ASD appear to have a much higher exposure to Aluminum from vaccines. The study points out that several prominent milestones of brain development coincide with major vaccination periods for infants. These include the onset of synaptogenesis (birth), maximal growth velocity of the hippocampus and the onset of amygdala maturation. Furthermore, major developmental transition in many bio-behavioural symptoms such as sleep, temperature regulation, respiration and brain wave patterns, all of which are regulated by the neuroendocrine network. Many of these aspects of brain function are known to be impaired in autism, such as sleeping and brain wave patterns.
According to the FDA, vaccines represent a special category of drugs as they are generally given to healthy individuals. Further according to the FDA, “this places significant emphasis on their vaccine safety.” While the FDA does set an upper limit for Aluminum in vaccines at no more that 850/mg/dose, it is important to note that this amount was selected empirically from data showing that Aluminum in such amounts enhanced the antigenicity of the vaccine, rather than from existing safety. Given that the scientific evidence appears to indicate that vaccine safety is not as firmly established as often believed, it would seem ill advised to exclude paediatric vaccinations as a possible cause of adverse long-term neurodevelopment outcomes, including those associated with autism.
A study published in the (http://www.ncbi.nlm.nih.gov/pubmed/21623535) Journal of Toxicology and Environmental Health, Part A: Current Issues (http://www.ncbi.nlm.nih.gov/pubmed/21623535) by the Department of Economics and Finance at the University of New York shows how researchers suspect one or more environmental triggers are needed to develop autism, regardless of whether individuals have a genetic predisposition or not. They determined that one of those triggers might be the “battery of vaccinations that young children receive.” Researchers found a positive and statistically significant relationship between autism and vaccinations. They determined that the higher the proportion of children receiving recommended vaccinations, the higher the prevalence of autism. A 1 % increase in vaccination was associated with an additional 680 children having autism. The results suggest that vaccines may be linked to autism and encourages more in depth study before continually administering these vaccines.

A study published in the (http://www.hindawi.com/journals/jt/2013/801517/)Journal of Toxicology (http://www.hindawi.com/journals/jt/2013/801517/) by the Department of Neurosurgery at The Methodist Neurological Institute in Houston has shown that ASD is a disorder caused by a problem in brain development. They looked at B-cells and their sensitivity levels to thimerosal, a commonly used additive in many vaccines. They determined that ASD patients have a heightened sensitivity to thimerosal which would restrict cell proliferation that is typically found after vaccination. The research shows that individuals who have this hypersensitivity to thimerosal could make them highly susceptible to toxins like thimerosal, and that individuals with a mild mitochondrial defect may be affected by thimerosal. The fact that ASD patients’ B cells exhibit hypersensitivity to thimerosal tells us something.

A study published in the Journal of Biomedical Sciences (http://www.ncbi.nlm.nih.gov/pubmed/12145534)determined that the autoimmunity to the central nervous system may play a causal role in autism. Researchers discovered that because many autistic children harbour elevated levels of measles antibodies, they should conduct a serological study of measles-mumps-rubella (MMR) and myelin basic protein (MBP) autoantibodies. They used serum samples of 125 autistic children and 92 controlled children. Their analysis showed a significant increase in the level of MMR antibodies in autistic children. The study concludes that the autistic children had an inappropriate or abnormal antibody response to MMR. The study determined that autism could be a result from an atypical measles infection that produces neurological symptoms in some children. The source of this virus could be a variant of MV, or it could be the MMR vaccine.

Study published in the (http://www.collective-evolution.com/2013/09/12/22-medical-studies-that-show-vaccines-can-cause-autism/Study%20published%20in%20the%20Annals%20of%20Clinical%20Psychiatry)Annals of Clinical Psychiatry (http://www.collective-evolution.com/2013/09/12/22-medical-studies-that-show-vaccines-can-cause-autism/Study%20published%20in%20the%20Annals%20of%20Clinical%20Psychiatry) suggests that Autism is likely triggered by a virus, and that measles virus (MV and/or MMR vaccine) might be a very good candidate. It supports the hypothesis that a virus-dincued autoimmune response may play a causal role in autism.

A study published in the (http://ajcn.nutrition.org/content/80/6/1611.full)American Journal of Clinical Nutrition (http://ajcn.nutrition.org/content/80/6/1611.full) determined that an increased vulnerability to oxidative stress and decreased capacity for methylation may contribute to the development and clinical manifestation of autism. It’s well known that viral infections cause increased oxidative stress. Research suggests (http://www.ncbi.nlm.nih.gov/pubmed/11895129) that metals, including those found in many vaccines are directly involved in increasing oxidative stress.

A study published by the Department of Pharmaceutical Sciences (http://www.ncbi.nlm.nih.gov/pubmed/14745455) at Northeastern University, Boston determined that a novel growth factor signalling pathway that regulates methionine synthase(MS) activity and thereby modulates methylation reactions. The potent inhibition of this pathway by ethanol, lead, mercury, aluminum and thimerosal suggests that it may be an important target of neurodevelopmental toxins. You can read more about this here (http://legacy.autism.com/medical/research/deth.htm), and here (https://imfar.confex.com/imfar/2010/webprogram/Paper5280.html). You can read more about the MS/autism link here (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0056927)

A study published in the Journal of Child Neurology (http://jcn.sagepub.com/content/22/11/1308.abstract)examined the question of what is leading to the apparent increase in autism. They expressed that if there is any link between autism and mercury, it is crucial that the first reports of the question are not falsely stating that no link occurs. Researchers determined that a significant relation does exist between the blood levels of mercury and the diagnosis of an autism spectrum disorder.

A study published in the (http://jcn.sagepub.com/content/21/2/170.abstract) Journal of Child Neurology (http://jcn.sagepub.com/content/21/2/170.abstract) noted that autistic spectrum disorders can be associated with mitochondrial dysfunction. Researchers determined that children who have mitochondrial-related dysfunctional cellular energy metabolism might be more prone to undergo autistic regression between 18 and 30 months of age if they also have infections or immunizations at the same time.

A study conducted by Massachusetts General Hospital (http://www.ncbi.nlm.nih.gov/pubmed/16151044) at the Centre for Morphometric Analysis by the department of Paediatric Neurology illustrates how autistic brains have a growth spurt shortly after birth and then slow in growth a few short years later. Researchers have determined that neuroinflammation appears to be present in autistic brain tissue from childhood through adulthood. The study excerpt reads:
Oxidative stress, brain inflammation and microgliosis have been much documented in association with toxic exposures including various heavy metals. The awareness that the brain as well as medical conditions of children with autism may be conditioned by chronic biomedical abnormalities such as inflammation opens the possibility that meaningful biomedical interventions may be possible well past the window of maximal neuroplasticity in early childhood because the basis for assuming that all deficits can be attributed to fixed early developmental alterations in net
A study conducted by the Department of Paediatrics at the University of Arkansas (http://www.ncbi.nlm.nih.gov/pubmed/15527868) determined that thimerosal-induced cytotoxicity was associated with the depletion of intracellular glutathione (GSH) in both cell lines. The study outlines how many vaccines have been neurotoxic, especially to the developing brain. Depletion of GSH is commonly associated with autism. Although thimerosal has been removed from most children’s vaccines, it is still present in flu vaccines given to pregnant women, the elderly and to children in developing countries.

A study published in the (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0068444)Public Library of Science (PLOS) (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0068444) determined that elevation in peripheral oxidative stress is consistent with, and may contribute to more severe functional impairments in the ASD group. We know that oxidative stress is triggered by heavy metals, like the ones contained in multiple vaccines.

A study conducted by the University of Texas Health Science Centre (http://www.ncbi.nlm.nih.gov/pubmed/16338635) by the Department of Family and Community Medicine determined that for each 1,000 Ib of environmentally released mercury, there was a 43% increase in the rate of special education services and a 61% increase in the rate of autism. Researchers emphasized that further research was needed regarding the association between environmentally released mercury and developmental disorders such as autism.

A study published in the International Journal of Toxicology (http://www.ncbi.nlm.nih.gov/pubmed/12933322) determined that in light of the biological plausibility of mercury’s role in neurodevelopment disorders, the present study provides further insight into one possible mechanism by which early mercury exposures could increase the risk of autism.

A study published in the (http://www.ncbi.nlm.nih.gov/pubmed/17454560)Journal of Toxicology and Environmental Health (http://www.ncbi.nlm.nih.gov/pubmed/17454560) determined that mercury exposure can induce immune, sensory, neurological, motor and behavioural dysfunctions similar to traits defining or associated with ASDs. Based upon differential diagnoses, 8 of 9 patients examined were exposed to significant mercury from Thimerosal-containing vaccine preparations during their fetal/infant developmental periods. These previously normal developing children suffered mercury encephalopathies that manifested with clinical symptoms consistent with regressive ASDs. Evidence for mercury intoxication should be considered in the differential diagnosis as contributing to some regressive ASDs.

A study published by the US National Library of Medicine (http://civileats.com/wp-content/uploads/2009/01/palmer2008.pdf)conducted by the University of Texas Health Science Centre suspected that persistent low-dose exposures to various environmental toxicants including mercury, that occur during critical windows of neural development among genetically susceptible children, may increase the risk for developmental disorders such as autism.

A study conducted by the Department of Obstetrics and Gynaecology (http://www.ane.pl/pdf/7020.pdf) at University of Pittsburgh’s School of Medicine showed that Macaques are commonly used in pre-clinical vaccine safety testing. Collective Evolution does not support animal testing, we feel there is a large amount of evidence and research that already indicated the links to vaccines in which some animals have been used to illustrate. The objective of this study was to compare early infant cognition and behaviour with amygdala size and opioid binding in rhesus macaques receiving the recommended childhood vaccines. The animal model, which examines for the first time, behavioural, functional and neuromorphometric consequences of the childhood vaccine regimen, mimics certain neurological abnormalities of autism. These findings raise important safety issues while providing a potential model for examining aspects of causation and disease pathogenesis in acquired disorders of behaviour and development.

A study conducted by The George Washington University School of Public Health (http://www.ncbi.nlm.nih.gov/pubmed/18482737) from the Department of Epidemiology and Biostatistics determined that significantly increased rate ratios were observed for autism and autism spectrum disorders as a result of exposure to mercury from Thimerosal-containing vaccines.

A study published in the Journal Cell Biology and Toxicology (http://www.ncbi.nlm.nih.gov/pubmed/19357975) by Kinki University in Osaka, Japan determined that in combination with the brain pathology observed in patients diagnosed with autism, the present study helps to support the possible biological plausability for how low-dose exposure to mercury from thimerosal-containing vaccines may be associated with autism.

A study published by the (http://labmed.ascpjournals.org/content/33/9/708.full.pdf) Journal Lab Medicine (http://labmed.ascpjournals.org/content/33/9/708.full.pdf) determined that vaccinations may be one of the triggers for autism. Researchers discovered that substantial data demonstrates immune abnormality in many autistic children consistent with impaired resistance to infection, activation of inflammatory responses and autoimmunity. Impaired resistance may predispose to vaccine injury in autism.

A study published in the Journal (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/?tool=pubmed)Neurochemical Research (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/?tool=pubmed) determined that since excessive accumulation of extracellular glutamate is linked with excitotoxicity, data implies that neonatal exposure to thimerosal-containing vaccines might induce excitotoxic brain injuries, leading to neurodevelopmental disorders.


Sources:

(1) http://www.fda.gov/downloads/biologicsbloodvaccines/vaccines/approvedproducts/ucm101580.pdf (http://www.fda.gov/downloads/biologicsbloodvaccines/vaccines/approvedproducts/ucm101580.pdf)

(2) http://www.ncbi.nlm.nih.gov/pubmed/24354891 (http://www.ncbi.nlm.nih.gov/pubmed/24354891)

(3) http://nsnbc.me/wp-content/uploads/2013/05/BSEM-2011.pdf (http://nsnbc.me/wp-content/uploads/2013/05/BSEM-2011.pdf)

Tesla_WTC_Solution
24th April 2014, 15:24
thank you so much for taking the trouble to compile and post that.
sometimes i let the "wrong side" beat me, convince me we're crazy here,

but we're not -

Hervé
24th April 2014, 17:59
thank you so much for taking the trouble to compile and post that.
sometimes i let the "wrong side" beat me, convince me we're crazy here,

but we're not -

... errrr... :fie:

I didn't compile the whole thing, Arjun Walia (http://www.collective-evolution.com/author/arjun/) did and posted it at: http://www.collective-evolution.com/2014/04/09/fda-document-reports-autism-link-after-tetanus-pertussis-diptheria-combination-vaccine/

...where the hyperlink under the title (blue highlight) would have led you: FDA Document Reports Autism Link After Tetanus, Pertussis & Diptheria Combination Vaccine (http://www.collective-evolution.com/2014/04/09/fda-document-reports-autism-link-after-tetanus-pertussis-diptheria-combination-vaccine/) (<--- click :) )

In any, case thank you for appreciating it!

Tesla_WTC_Solution
24th April 2014, 19:54
http://www.ncbi.nlm.nih.gov/pubmed/23318464

Behav Brain Res. 2013 Apr 15;243:138-45. doi: 10.1016/j.bbr.2012.12.062. Epub 2013 Jan 11.

Heparan sulfate deficiency in autistic postmortem brain tissue from the subventricular zone of the lateral ventricles.

Pearson BL1, Corley MJ, Vasconcellos A, Blanchard DC, Blanchard RJ.
Author information
Abstract

Abnormal cellular growth and organization have been characterized in postmortem tissue from brains of autistic individuals, suggestive of pathology in a critical neurogenic niche, the subventricular zone (SVZ) of the brain lateral ventricles (LV). We examined cellular organization, cell proliferation, and constituents of the extracellular matrix such as N-sulfated heparan sulfate (HS) and laminin (LAM) in postmortem brain tissue from the LV-SVZ of young to elderly individuals with autism (n=4) and age-matched typically developing (TD) individuals (n=4) using immunofluorescence techniques. Strong and systematic reductions in HS immunofluorescence were observed in the LV-SVZ of the TD individuals with increasing age. For young through mature, but not elderly, autistic pair members, HS was reduced compared to their matched TDs. Cellular proliferation (Ki67+) was higher in the autistic individual of the youngest age-matched pair. These preliminary data suggesting that HS may be reduced in young to mature autistic individuals are in agreement with previous findings from the BTBR T+tf/J mouse, an animal model of autism; from mice with genetic modifications reducing HS; and with genetic variants in HS-related genes in autism. They suggest that aberrant extracellular matrix glycosaminoglycan function localized to the subventricular zone of the lateral ventricles may be a biomarker for autism, and potentially involved in the etiology of the disorder.

Copyright © 2013 Elsevier B.V. All rights reserved.

PMID: 23318464 [PubMed - indexed for MEDLINE] PMCID: PMC3594061 Free PMC Article


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Roundup: The “Nontoxic” Chemical that May Be Destroying our Health PDF Print E-mail
Written by Stephanie Seneff, PhD
Wednesday, 30 October 2013 18:09
According to Monsanto, producer of Roundup®, the most popular herbicide used on the planet, the product is nearly nontoxic for humans. The usage of Roundup to kill weeds has skyrocketed around the world since the year 2000, in part because it went off patent that year, but also because of the enormous increase (especially in the U.S.) in the appearance of “Roundup-Ready” GMO crops.4
Glyphosate, the active ingredient in Roundup, kills weeds by interfering with what is called the shikimate pathway. This pathway is essential in plants for the synthesis of a class of amino acids called the “aromatics.” But this pathway is nonexistent in any mammalian cell. By simple logic, the fact that our cells don’t have this pathway means that glyphosate cannot harm us. Is there a fallacy in this argument?
GLYPHOSATE CONNECTION TO DISEASE

While mammals don’t possess the shikimate pathway, all of the microbes that take up residence in our digestive tract do have this pathway, and exposure to glyphosate, the active ingredient in Roundup, will cause them serious stress as a consequence. Studies have shown that glyphosate disrupts the gut bacteria in chickens, 54 cows,29 and pigs,10 causing inflammation in the gut along with an overgrowth of pathogenic forms and concurrent loss of beneficial bacteria. It is now becoming apparent that our gut bacteria, which outnumber our own cells by a factor of ten to one, play many important roles in supplying nutrients and protecting us from toxins.19 There’s also an intricate connection between the gut and the brain, such that an unhealthy digestive system translates into pathologies in the brain.35
Together with Anthony Samsel, I recently published a paper arguing that Roundup® could plausibly be the most important factor in the observed increase in a number of diseases and conditions like obesity and autism over the past two decades in the U.S.47 Despite spending nearly two and a half times as much on health care as our peer nations,36 the U.S. lags behind many of these other nations in basic metrics like infant mortality and life expectancy.34 The most recent figures for infant mortality place the U.S. at number forty-six, behind Cuba and Guam. Clearly we are doing something wrong, and our wholesale embrace of GMOs is an obvious candidate.
Ninety percent of the GMO crops (GMO corn, soy, cotton, sugar beets, and canola) are engineered to be “Roundup Ready,” which means that they can be sprayed with Roundup and they will happily soak it up into their tissues. The practice of “desiccating” crops like wheat and sugar cane just before the harvest by spraying them with Roundup is also becoming more and more popular as a way to reduce the amount of vegetation that needs to be cleared in preparation for planting next year’s crop. These two changes in agricultural practices almost certainly mean that Roundup is entering our food supply in record amounts. And most homeowners are likely careless in their use of Roundup to fight weeds on the lawn, due to a misconception that it is nearly nontoxic. A recent study involved sampling glyphosate in the urine of city-dwellers in eighteen European countries.23 Measurable amounts of glyphosate were found in 44 percent of these people, despite the fact that Europe has a much more conservative view towards GMOs than does the U.S.
So, why is the shikimate pathway so important? Plants and microbes use the shikimate pathway to produce the aromatic amino acids, tryptophan, tyrosine and phenylalanine.22 Because they don’t have this pathway, mammals can’t produce these essential nutrients, and therefore we depend on plants and microbes to provide them for us. So it is logical that glyphosate, by interfering with this pathway, would lead to a deficiency in these nutrients. Tryptophan is the sole precursor to serotonin, and serotonin deficiency is implicated in a litany of diseases and conditions that are prevalent today, including autism, obesity, Alzheimer’s disease, depression, suicide, and homicidal behavior.47 Serotonin is an appetite suppressant8 so it’s hard not to overeat when it is in short supply. If you are disciplined to resist these urges, then you run the risk of depression and Alzheimer’s disease, or autism in your children. Serotonin is the precursor to melatonin, the neurotransmitter that regulates the wake-sleep cycle, and melatonin deficiency is also implicated in autism.2,39 Tyrosine is the precursor to dopamine,41 and impaired dopamine supply is the key defect associated with Parkinson’s disease. Glyphosate activates an enzyme called phenylalanine ammonia lyase (PAL), which breaks down phenylalanine and releases ammonia as a by-product.33 Excess ammonia in the blood stream can trigger a cascade leading to encephalitis and seizures.30

AUTISM EPIDEMIC AND ROUNDUP USAGE

Autism is a condition characterized by cognitive and social deficits, which has been alarmingly on the rise in the last decade. Some children seem to be born with the condition, while others develop normally up to a certain point and then begin regressing into autism.55 Autism is associated with two comorbidities that may yield hints as to its underlying etiology: disrupted gut bacteria and impaired sulfur metabolism.57 A characteristic feature of children with autism is an overgrowth of pathogenic bacteria in the gut, which can lead to neurological defects arising from exposure of the brain to toxins produced by these bacteria.24,56,58
I have been studying autism for many years, trying to understand the environmental factors that might be causal in the current epidemic in this complex condition. Autism used to be rare, affecting one in ten thousand children. The latest numbers put out by the CDC in March 2013, show one in fifty.6 This is an alarming number, and, what is even more alarming is how quickly the number has been rising in recent years. Figure 1 shows a plot of autism rates over the past twenty years alongside a plot of total Roundup usage on corn and soy in the U.S., the two core crops of the processed food industry. It is remarkable how well these two plots line up. The Pearson correlation coefficient is 0.985 (1.0 would be perfect alignment). This plot also demonstrates the alarming increases in glyphosate application that have followed the insertion of the Roundup Ready GMO bacterial gene into the seeds.
Correlation does not necessarily mean causation, but if you can explain logically how A might lead to B, then the likelihood of causation goes way up. It took a long time before I thought of glyphosate as a possible factor in autism, probably because I believed Monsanto’s claims that it is relatively nontoxic. This all changed when I heard a lecture given by Professor Don Huber at the 2012 Indianapolis WAPF chapter conference. His explanation of the effects of glyphosate on biological systems filled in important gaps in the theory I was developing to explain the underlying pathologies in autism.

Most striking, of course, is the disruption of gut bacteria, something that Natasha Campbell McBride has been speaking about for many years at WAPF conferences and in her books.9 A recent study involving nearly three thousand children with autism spectrum disorder (ASD) found that a quarter of them suffered from chronic GI problems like constipation, diarrhea, and bloating.37 This subset had significantly higher rates of both anxiety and over-sensitivity to sensory stimulation.
AUTISM, PATHOGENS, AND SULFATE

As Anthony Samsel and I gathered information about glyphosate, we began to see a striking pattern linking glyphosate to specific pathogens like Clostridia difficile (C. diff ) and Pseudomonas aeruginosa, which are currently causing a major crisis in hospitals in the U.S. and elsewhere due to their increased prevalence and multiple antibiotic resistance.12, 28 Pseudomonas is among the very few bacterial forms that can metabolize glyphosate. A breakdown product is formaldehyde, a known carcinogen and neurotoxin.43 Formaldehyde may however be preferred over glyphosate as the lesser of two evils. So we surmise that this bacterium is allowed to survive in the gut precisely because it can dispose of glyphosate, but then you have to suffer the consequences of formaldehyde toxicity.

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Figure 1: Autism rates in the U.S. school system and of the amount of glyphosate used on corn and soy acreage in the U.S. Figure generously provided by Nancy Swanson: www.examiner.com/article/data-show-correlations-between-increase-neurological-diseases-and-gmos.
Explaining the overgrowth of C. diff requires a digression. My extensive research has led me to believe that systemic sulfate deficiency may be the most important factor in many of the health issues facing us today.21, 48 Certainly it is a factor in autism. Autistic children have been found to have only one third as much free sulfate in the blood as their normal peers.57 The essential sulfur-containing amino acid, methionine, is a source of both sulfur and methyl groups to the body, both of which are crucial for normal brain development.17,21,26 Heparan sulfate is a sulfated molecule derived from sugar which plays remarkable roles in regulating ion and nutrient transport as well as molecular signaling cascades, for most of the body’s cells.5 It’s also crucial in brain development of the fetus.12 A loss of heparan sulfate in the gut lining results in protein leaks into the blood,7 which can then induce gluten and casein intolerance, which are common among autistic children. Mice engineered to be impaired in heparan sulfate synthesis in the brain exhibit all of the features of autism.27
C. diff produces a toxic phenol called p- Cresol, which has been identified as a factor present in the urine in association with autism.1 In fact, as we gathered more data on glyphosate and its effects on plants, we noticed that phenolic compounds, more generally, are produced by both plants and microbes upon exposure to glyphosate, along with the over-production of other compounds with carbon rings called flavonoids. You may be aware that flavonoids in coffee, tea, and brightly colored vegetables and polyphenolic compounds like resveratrol and curcumin are considered to be beneficial for their antioxidant properties. I believe that their beneficial effect may actually be due to their ability to safely transport sulfate, a feature they all possess, and a feature they share with the toxic phenols such as those produced by the pathogen C. diff.
SULFATE TRANSPORT AND CARBON RINGS

Extensive prior research has led me to a hypothesis that sulfate transport in the blood poses a special challenge to the body, and that this may be the main reason why there is a plethora of biologically interesting molecules that are typically sulfated when they are transported in the blood, as well as a huge number of sulfotransferases that can attach these sulfates15 and transfer them from one molecule to another. I suspect that one of the important but heretofore overlooked consequences is that they transport sulfate from a source site in the body such as the gut to a delivery site such as the liver, the pancreas, or the brain, and that this is a crucial part of their function in biology.
Two major classes of these biologically active sulfate-transporting molecules are the sterols (cholesterol, vitamin D3, DHEA, estrone) and the monoamine neurotransmitters (dopamine, serotonin, norepinephrine). All of these molecules have the interesting property that their biological effects are inactivated when they are sulfated. This is of course beneficial so that they are inert during transport, an attractive feature. But I believe that, more important than this, is the fact that the sulfate that is attached to these molecules is also inactive while being transported. And it might even be the case that one of the most important functions these molecules perform is to transport sulfate! All of these molecules share the property that the sulfate anion is attached to a carbon ring, and the ring distributes the negative charge on the sulfate, changing its biophysical properties in important ways.
What are these biophysical properties? Sulfate is a member of a class of anions called anionic kosmotropes. Other biologically important members of this class are phosphates and carbonates, both of which are also pervasive in biological systems. These three anions are essential for maintaining the water in the immediate vicinity of the cells’ plasma membranes in the tissues and of particles suspended in the blood in a structured almost crystal-like “liquid ice” configuration, creating a protective “exclusion zone” (the glycocalyx).45 Gelatin desserts are a familiar version of this structured water—it’s mainly carbonate that structures the water in this case. Water is by far the most common molecule in our bodies, yet this is hard to imagine given how firm our bodies are. With 99 percent of our molecules being water, it’s surprising that we don’t just collapse into a puddle! Pollack believes that the main reason our tissues are not liquid is that nearly all the water is maintained in a gelled state by these kosmotropes.45
However, the one big exception to this model is the blood. The blood that courses through our veins is definitely a liquid, and if it were to become gelled it would lead to a no-flow situation and a major catastrophe. This, to me, is the key reason why all these biologically active molecules travel through the blood stream in a sulfated form.

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Figure 2: The molecular structure of glyphosate.
Now let’s consider what happens when glyphosate enters the picture. Glyphosate is almost certainly an anionic kosmotrope as well. As shown in Figure 2, it contains a carbonyl group and a phosphonyl group, and it doesn’t have any carbon rings. When a person takes an overdose of glyphosate in an attempt to commit suicide, a blood pathology called “disseminated intravascular coagulation” (DIC) ensues59 and this can easily be fatal. So glyphosate causes an increase in blood viscosity and competes with free sulfate, which also has this effect, for a limited load capacity. This problem would be especially acute in the hepatic portal vein carrying nutrients from the gut to the liver. The liver desperately depends on sulfate to make cholesterol sulfate, which is essential in the synthesis of bile acids, and bile acids in turn are essential for digesting fats. Cholesterol sulfate also plays an important role in the outer shell of LDL and HDL particles, to protect them from reactive agents in the blood (e.g., oxidizing and glycating agents). The “small dense LDL particles” that are most damaging in heart disease arise because of oxidation and glycation damage that disrupts the lock-and-key mechanism during reuptake in the liver after they have delivered their goods, and therefore prevents them from being recycled. So, insufficient sulfate leads to LDL and HDL particles that are more susceptible to such damage, a key factor in heart disease.
In addition to “jamming the waterways” in blood vessels, glyphosate also interferes with the supply of sulfate carrier molecules that depend on the shikimate pathway. Dopamine, serotonin and norepinephrine are all derived from the aromatic amino acids whose synthesis is blocked by glyphosate. Worse than this, glyphosate also interferes with a class of enzymes called cytochrome P450 enzymes (CYP enzymes for short),31 which play many different roles in the body, especially in the liver and the reproductive system.42 Certain members of this class are essential for bile acid synthesis. These enzymes are also involved in cholesterol homeostasis and vitamin D activation in the liver, whose disruption will further interfere with sulfate transport, among other problems.
In our recent paper on glyphosate47 we argued that the toxic phenolic compounds like p-Cresol that are produced by pathogenic bacteria like C. diff actually perform an important service by transporting sulfate from the gut to the liver and pancreas. According to this hypothesis, toxic phenolic compounds are produced because the sterols and monoamine neurotransmitters are impaired in their ability to perform this much-needed service. However, once the phenol drops off its sulfate, it becomes a highly reactive molecule, capable of doing damage to the lipids and DNA in the liver and pancreas, as well as in the gut, as a single phenol is likely cycled around again and again to deliver multiple sulfates to the liver and pancreas, and, whenever it’s not sulfated, it’s toxic.
SUMMARY

In this paper, I have developed an argument that, contrary to Monsanto’s assurances, glyphosate is not a safe chemical for human exposure. On the contrary, glyphosate’s well established effects in biological systems can plausibly explain many of the diseases and conditions we are experiencing today in epidemic form. These include autism, Alzheimer’s, obesity, depression, excessive violence, colitis, inflammatory bowel disease, heart disease and diabetes. I now believe that, while several environmental toxicants, including mercury, aluminum, lead, fluoride, nitrates, insecticides and fungicides, are likely implicated in autism, glyphosate may be the single most important factor in the autism epidemic. I believe this not only because glyphosate usage has gone up in step with autism rates, but also because many of the pathologies associated with autism can be explained through glyphosate’s disruptive mechanisms.
I also would argue that Alzheimer’s disease arises from similar pathologies as does autism, and it might be characterized as “autism for the elderly.” Therefore, its recent alarming increases may also be due predominantly to glyphosate.
Glyphosate can also easily explain the obesity epidemic and depression through its disruption of the supply of tryptophan, the sole precursor to serotonin. I have shown how glyphosate disrupts both sulfate synthesis and sulfate transport, and my research has led me to believe that impaired sulfate supply to all the tissues is a common underlying pathology in most modern diseases.
The best way to minimize glyphosate exposure is to adhere strictly to a completely organic diet. Most important is to avoid all the Roundup-Ready GMO crops: corn, soy, sugar beets, canola oil, and cottonseed oil, as well as wheat and sugar cane, due to desiccation practices. Any use of Roundup to kill weeds in lawn maintenance should be abandoned.
SIDEBARS

OTHER HEALTH TROUBLES RELATED TO GLYPHOSATE

As if it weren’t enough already that glyphosate causes an overgrowth of pathogenic bacteria in the gut, interferes with the supply of critical neurotransmitters to the brain and nervous system, and likely disrupts vitamin D activation, bile acid synthesis, cholesterol homeostasis, and sulfate synthesis and transport, there are several other ways in which glyphosate could do harm. Here I will touch upon four topics: endocrine disruption, liver damage, abdominal obesity, and breast cancer. Additional topics are discussed in our original paper.47 For example, glyphosate also chelates important micronutrients like zinc and cobalt.14

ENDOCRINE DISRUPTION: Glyphosate is an established endocrine disruptor16 and studies have shown it inhibits aromatase, a CYP enzyme that converts testosterone to estrogen.46 Aromatase is synthesized in the testes,32 and this may explain why autism is far more prevalent in males than in females. Autism is associated with aromatase deficiency, and some have attempted to explain autism as a “super male” syndrome on the basis of overproduction of testosterone and insufficient estrogen.3 Retinoic acid is intimately involved in embryonic development. Low doses of glyphosate caused many deformities in frog and chick embryos44 due to overexpression of retinoic acid. The enzyme that breaks down retinoic acid is a CYP enzyme, so its disruption would explain glyphosate’s effects. One can expect similar effects in humans. Fertility rates have been declining sharply in many countries where glyphosate usage is increasing. Most striking are countries in South America such as Argentina and Brazil. Women in Brazil used to have six children on average, but now the fertility rate is less than that of the U.S. Argentina’s fertility rate has been declining ever since 1978. Both Brazil and Argentina produce a significant amount of the world’s supply of soybeans—most of which are engineered to be “Roundup® Ready.” While it’s difficult to sort out the role played by social pressure, it is possible that glyphosate’s disruption of aromatase and retinoic acid could be a factor in declining fertility rates.

LIVER DAMAGE : According to our hypothesis, phenols are sulfated in the gut and transported through the hepatic portal vein to the liver in this sulfated form. In the liver, the sulfate is detached and most likely transferred to cholesterol to produce bile acids. Once freed from sulfate, phenolic compounds become fat-soluble and highly reactive, and they can readily cross cell membranes and do damage to cell contents. Phenols have been shown to cause damage to the kidneys, liver, muscles, and eyes.40 They induce the formation of organic radicals and reactive oxygen species that can damage lipids and DNA, which explains their ability to induce cancer. However, a much worse problem in the liver is the disruption of CYP enzymes, because the liver contains many CYP enzymes that are involved in detoxifying xenobiotics—both drugs and environmental toxins. With impaired CYP function, these other toxic chemicals linger longer, causing much more damage than they would otherwise. In fact, an inability to break down acetaminophen (Tylenol) has been proposed as a possible factor in autism.49 This can easily be explained by glyphosate’s potential disruption of the CYP enzyme that detoxifies Tylenol. The inflammation associated with the overgrowth of pathogens in the gut leads to the production of cytokines like TNF-∂ by macrophages, brought in to keep the pathogens in check. Cytokines induce inflammation, which damages the gut, liver and pancreas. TNF-∂ has been identified as a key factor in fatty liver disease, which has emerged as a growing public health problem worldwide.11 In the extreme case, liver pathology develops into nonalcoholic steatohepatitis (NASH), which can lead to cirrhosis and liver failure.
ABDOMINAL OBESITY : It is easy to imagine a possible role for fat cells in protecting the liver from damage caused by the toxic phenols. Abdominal obesity can be viewed as providing a way station where sulfate can be transferred from one carrier molecule to another. The toxic phenols can thus deliver sulfate to fat cells in the belly, which then transfer it to a sterol to produce estrone sulfate, a well established “export” molecule from fat cells.52 Thus estrone then carries the sulfate to the liver, and the phenol never reaches the liver or the pancreas, where it could have damaged the DNA of cells with important roles. The liver and pancreas are never exposed to the toxic phenolic compound, and are therefore safeguarded from damage. Thus, abdominal obesity becomes a defense mechanism to deflect the phenols towards a tissue where damage is more forgivable, since the fat cells do not perform the kinds of critical metabolic roles that liver or pancreatic cells perform.

BREAST CANCER : One in eight women in the U.S. is now expected to develop breast cancer at some point in their lives. A study on rats that were administered food that had been treated with Roundup throughout their lives showed an alarming incidence of massive mammary tumors in the female rats50 along with liver and kidney disease in the males, and premature death for both males and females. After our paper was published, a study came out showing that glyphosate, even in trace amounts (parts per trillion) could induce breast cancer cells to proliferate; that is, it promotes tumor growth.53

GLYPHOSATE USAGE AND DISEASE RATES

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15. Gamage, N.; Barnett, A.; Hempel, N.; Duggleby, R.G.; Windmill, K.F.; Martin, J.L.; McManus, M.E. Human sulfotransferases and their role in chemical metabolism. Toxicol. Sci. 2006, 90(1), 5-22.
16. Gasnier, C.; Dumont, C.; Benachour, N.; Clair, E.; Chagnon, M.C.; Séralini, G.E. Glyphosate-based herbicides are toxic and endocrine disruptors in human cell lines. Toxicology 2009, 262, 184-191.
17. Geiman, T.M.; Muegge, K. DNA methylation in early development. Mol. Reprod. Dev. 2010, 77, 105-113.
18. Gorren, A.C.; Mayer, B. Nitric-oxide synthase: A cytochrome P450 family foster child. Biochim. Biophys. Acta 2007, 1770, 432-445.
19. Guarner, F.; Malagelada, J.-R. Gut flora in health and disease. The Lancet 2003, 360, 512-519.
20. Guzik, T. J.; Korbut, R.; Adamek-Guzik, T. Nitric oxide and superoxide in inflammation and immune regulation. Journal of Physiology and Pharmacology 2003, 54, 46987.
21. Hartzell, S.; Seneff, S. Impaired sulfate metabolism and epigenetics: Is there a link in autism? Entropy 2012, 14, 1953-1977.
22. Herrmann, K.M.; Weaver, L.M. The shikimate pathway. Annu. Rev. Plant. Physiol. Plant. Mol. Biol. 1999, 50, 473-503.
23. Hoppe, H.-W. Determination of glyphosate residues in human urine samples from 18 European countries. Medical Laboratory Bremen, June 12, 2013. http://stats.foeeurope.org/piwik.js. [accessed July 5, 2013].
24. Horvath, K.; Perman, J.A. Autism and gastrointestinal symptoms. Current Gastroenterology Reports 2002, 4, 251-258.
25. Hietanen, E.; Linnainmaa, K.; Vainio, H. Effects of phenoxyherbicides and glyphosate on the hepatic and intestinal biotransformation activities in the rat. Acta. Pharmacol. Toxicol. 1983, 53, 103-112.
26. Inatani, M.; Irie, F.; Plump, A.S.; Tessier-Lavigne, M.; Yamaguchi, Y. Mammalian brain morphogenesis and midline axon guidance require heparan sulfate. Science 2003, 302(5647), 1044-1046.
27. Irie, F.; Badie-Mahdavi, H.; Yamaguchi, Y. Autism-like socio-communicative deficits and stereotypies in mice lacking heparan sulfate. Proc. Natl. Acad. Sci. USA 2012, 109, 5052-5056.
28. Issa, M.; Vijayapal, A.; Graham, M.B.; Beaulieu, D.B.; Otterson, M.F.; Lundeen, S.; Skaros, S.; Weber, L.R.; Komorowski, R.A.; Knox, J.F.; Emmons, J.; Bajaj, J.S.; Binion, D.G. Impact of Clostridium difficile on inflammatory bowel disease. Clin. Gastroenterol. Hepatol. 2007, 5, 345-351.
29. Kruger, M.; Shehata, A.A.; Schrodl, W.; Rodloff, A. Glyphosate suppresses the antagonistic effect of Enterococcus spp. on Clostridium botulinum. Anaerobe 2013, 20, 74-78.
30. Lai, J.C.K.; Cooper, A.J.L. Neurotoxicity of ammonia and fatty acids: Differential inhibition of mitochondrial dehydrogenases by ammonia and fatty acyl coenzyme A derivatives. Neurochemical Research 1991, 16(7), 795-803.
31. Lamb, D.C.; Kelly, D.E.; Hanley, S.Z.; Mehmood, Z.; Kelly, S.L. Glyphosate is an inhibitor of plant cytochrome P450: Functional expression of Thlaspi arvensae cytochrome P45071b1/reductase fusion protein in Escherichia coli. Biochem. Biophys. Res. Comm. 1998, 244, 110-114.
32. Lambard, S.; Silandre, D.; Delalandec C.; Denis-Galeraud, I.; Bourguiba, S.; Carreau, S. Aromatase in testis: expression and role in male reproduction. J. Steroid Biochem. Mol. Biol. 2005, 95, 63-9.
33. MacDonald, M.J.; D’Cunha, G.B. A modern view of phenylalanine ammonia lyase. Biochem. Cell Biol. 2007, 85, 273-282.
34. Macdorman, M.F.; Mathews, T.J. Recent trends in infant mortality in the United States. NCHS Data Brief. 2008 Oct;(9):18.
35. Maes, M.; Kubera, M.; Leunis, J.-C. The gut-brain barrier in major depression: Intestinal mucosal dysfunction with an increased translocation of LPS from gram negative enterobacteria (leaky gut) plays a role in the inflammatory pathophysiology of depression. Neuroendocrin. Lett. 2008, 29, 117-124.
36. Masters, R.D. Cost and effectiveness in American health care. IJHS 2009, II, 221-226.
37. Mazurek, M.O.; Vasa, R.A.; Kalb, L.G.; Kanne, S.M.; Rosenberg, D.; Keefer, A.; Murray, D.S.; Freedman, B.; Lowery, L.A. Anxiety, sensory over-responsivity, and gastrointestinal problems in children with autism spectrum disorders. J. Abnorm. Child Psychol. 2013 Jan, 41(1), 165-76.
38. McGeer, E.G.; Klegeris, A.; McGeer, P.L. Neurobiology of Aging 2005, 26(1), 94-97.
39. Melke, J.; Goubran-Botros, H.; Chaste, P.; Betancur, C.; Nygren, G. et al. Abnormal melatonin synthesis in autism spectrum disorders. Mol. Psychiatry 2008 Jan, 13(1), 90-98.
40. Michalowicz, J.; Duda, W. Phenols Sources and toxicity. Polish J. of Environ. Stud. 2007, 16(3), 347-362.
41. Montgomery, A.J.; McTavish, S.F.B.; Cowen, P.J.; Grasby, P.M. Reduction of brain dopamine concentration with dietary tyrosine plus phenylalanine depletion: An [11C] Raclopride PET study. Am. J. Psychiatry 2003, 160, 1887-1889.
42. Nebert, D.W.; Russell, D.W. Clinical importance of the cytochromes P450. The Lancet 2002, 360, 1155-1162.
43. Nie, C.L.; Wang, X.S.; Liu, Y.; Perrett, S.; He, R.Q. Amyloid-like aggregates of neuronal tau induced by formaldehyde promote apoptosis of neuronal cells. BMC Neurosci. 2007, 8:9.
44. Paganelli, A.; Gnazzo, V.; Acosta, H.; Lpez, S.L.; Carrasco, A.E. Glyphosate-based herbicides produce teratogenic effects on vertebrates by impairing retinoic acid signaling. Chem. Res. Toxicol. 2010, 23, 1586-1595.
45. Pollack, G.H. The Fourth Phase of Water: Beyond Solid, Liquid, and Vapor. Ebner and Sons; First edition, May 2013.
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54. Shehata, A.A.; Schrodl, W.; Aldin, A.A.; Hafez, H.M.; Kruger, M. The effect of glyphosate on potential pathogens and beneficial members of poultry microbiota in vitro. Curr. Microbiol. 2013 66, 350-358.
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This article appeared in Wise Traditions in Food, Farming and the Healing Arts, the quarterly journal of the Weston A. Price Foundation, Fall 2013.






I think one of my greatest journalistic accomplishments was helping link Heparan Sulfate to autism spectrum disorder.

I felt so tired afterward too, like I had aged a year in a week.
More like a day actually.

http://nuclearnuttery.wordpress.com/tag/heparan-sulfate/

http://nuclearnuttery.files.wordpress.com/2012/08/tr.png?w=908


Hepatitis B virus infection initiates with a large surface protein-dependent binding to heparan sulfate proteoglycans.
Schulze A, Gripon P, Urban S.
Source

Department of Molecular Virology, Otto-Meyerhof-Zentrum (OMZ), University of Heidelberg, Heidelberg, Germany.
Abstract

Contrary to many other viruses, the initial steps of the hepatitis B virus (HBV) infection, including attachment to hepatocytes, specific receptor interactions, and membrane fusion, are unsolved. Using HepaRG cells as an in vitro cell culture system, we here report that HBV entry into hepatocytes depends on the interaction with the glycosaminoglycan (GAG) side chains of cell-surface-associated heparan sulfate proteoglycans. Binding to GAGs requires the integrity of the pre-S domain as a part of the large (L-) viral envelope protein. HBV infection was abrogated by incubation of virions with heparin, but not the structurally related GAGs chondroitin sulfate A, B, and C. Infection was also abolished by suramin, a known inhibitor of duck hepatitis B virus infection or highly sulfated dextran sulfate. Polycationic substances such as poly-L-lysine, polybrene, and protamine also prevented infection, however, by addressing cellular components. Enzymatic removal of defined acidic carbohydrate structures from the cell surface using heparinase I/III or the obstruction of GAG synthesis by sodium chlorate inhibited HBV infection of HepaRG cells and, moreover, led to a reduction of HBV cell surface binding sites. The biochemical analysis showed selective binding of L-protein-enriched viral particles (virions or filaments) to heparin. GAG-dependent binding of HBV was improved by polyethylene glycol, a substance that specifically enhances HBV infection. Conclusion: HBV infection requires the initial attachment to the carbohydrate side chains of hepatocyte-associated heparan sulfate proteoglycans as attachment receptors. This interaction initializes the multistep entry process of HBV and cannot be bypassed by alternative routes.

PMID:
18046710
[PubMed - indexed for MEDLINE]

Heparan sulfate and syndecan-1 are essential
in maintaining murine and human intestinal
epithelial barrier function
Lars Bode,1 Camilla Salvestrini,2 Pyong Woo Park,3 Jin-Ping Li,4 Jeffrey D. Esko,5
Yu Yamaguchi,1 Simon Murch,6 and Hudson H. Freeze1
1Burnham Institute for Medical Research, La Jolla, California, USA. 2Centre for Pediatric Gastroenterology, Royal Free Hospital, London, United Kingdom.
3Department of Medicine, Baylor College of Medicine, Houston, Texas, USA. 4Department of Medical Biochemistry and Microbiology, Biomedical Center,
Uppsala University, Uppsala, Sweden. 5Department of Cellular and Molecular Medicine, UCSD, La Jolla, California, USA.
6Clinical Sciences Research Institute, Warwick Medical School, Coventry, United Kingdom.

Patients with protein-losing enteropathy (PLE) fail to maintain intestinal epithelial barrier function and develop
an excessive and potentially fatal efflux of plasma proteins. PLE occurs in ostensibly unrelated diseases, but
emerging commonalities in clinical observations recently led us to identify key players in PLE pathogenesis.
These include elevated IFN-γ, TNF-α, venous hypertension, and the specific loss of heparan sulfate proteoglycans
from the basolateral surface of intestinal epithelial cells during PLE episodes. Here we show that heparan
sulfate and syndecan-1, the predominant intestinal epithelial heparan sulfate proteoglycan, are essential in
maintaining intestinal epithelial barrier function. Heparan sulfate– or syndecan-1–deficient mice and mice
with intestinal-specific loss of heparan sulfate had increased basal protein leakage and were far more susceptible
to protein loss induced by combinations of IFN-γ, TNF-α, and increased venous pressure. Similarly,
knockdown of syndecan-1 in human epithelial cells resulted in increased basal and cytokine-induced protein
leakage. Clinical application of heparin has been known to alleviate PLE in some patients but its unknown
mechanism and severe side effects due to its anticoagulant activity limit its usefulness. We demonstrate here
that non-anticoagulant 2,3-de-O-sulfated heparin could prevent intestinal protein leakage in syndecan-deficient
mice, suggesting that this may be a safe and effective therapy for PLE patients.

Autism: Oxidative Stress, Inflammation, and Immune Abnormalities
By Abha Chauhan, Ved Chauhan, Ted Brown

Leaky gut is a name used to describe intestinal or bowel hyperpermeability. Tight junctions (TJs) represent the major barrier within the pathway between intestinal epithelial cells that line the digestion tract. Disruption of TJs leads to intestinal hyperpermeability (the so-called “leaky gut”) which has been proposed by some researchers to involve a relationship with acute and chronic diseases such as systemic inflammatory response syndrome (SIRS), inflammatory bowel disease, type 1 diabetes, allergies, asthma, and autism.[1]

from wiki: A trio of factors including an aberrant intestinal microbiota, a “leaky” intestinal mucosal barrier, and altered intestinal immune responsiveness are hypothesised to play a role in the failure to form tolerance, resulting in the autoimmunity that underlies type 1 diabetes. [2]

A lack of mucosal integrity (leaky gut) with consecutive local and systemic inflammation and dysfunction of transport proteins may worsen the clinical symptoms of chronic heart failure. A ‘leaky’ bowel wall may lead to translocation of bacteria and/or endotoxin, which may be an important stimulus for inflammatory cytokine activation. Although it remains unclear whether increased adherent bacteria in patients with chronic heart failure are a primary or secondary event and whether they contribute to systemic inflammation. Further studies are needed to address the pathophysiology of the intestinal barrier whose reactivity seems to be crucial for heart function.[3][4]

Primary sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH) are enigmatic chronic inflammatory diseases of the liver, which can be associated with chronic inflammatory bowel diseases. Cross-recognition between microbial antigens in the gut and host components by the immune system along with stimulation of pattern recognition receptors might give rise to chronic hepatic inflammatory disorders with features of autoimmunity.[5]

SURFACE PROTEIN OF VIRUS CAUSES PROTEIN DEPLETION OF THE GUT AND ABNORMAL FLORA

AUTISM AND AIDS

Aisha Nazli, a researcher in Kaushic’s laboratory, noticed every time she put HIV on epithelial cells their resistance went down significantly. Repeated tests confirmed this.

Kaushic said the surface protein of the virus causes the epithelial barrier to break. “The surface protein signals to the inside of the epithelial cells by binding to it,” she said. “The epithelial cells start making inflammatory proteins which cause these cells to go on their self-destructive pathway.”

http://www.microbialinfluence.com/

We have collected many research articles to show that the toxins found in microorganisms play an important role in the suspected causes of ASD, in particular, lipopolysaccharide ( LPS) the bacterial toxins from gram negative bacteria that inhabit the guts of autistic children. LPS toxicity works synergistically with mercury and other heavy metal poisonings to expand damage. These heavy metals increase harm from LPS.[1] In addition, LPS decreases glutathione levels making it even more difficult for the body to detoxify heavy metals.[2]

One explanation for why symptoms of mercury are so similar to the symptoms of LPS could be the fact that mercury inhibits carbohydrate absorption in the gut. Unabsorbed food does not get into the blood stream quickly; when it remains in the gut, it becomes available as a food supply for bacteria. Consequently, gram negative bacteria multiply and produce LPS. [3] This raises a strong suspicion that some of the symptoms commonly attributed to mercury could be directly caused by LPS and only indirectly by mercury.

LPS also renders toxins from Candida Albicans more damaging.[4] The poisonous effects of LPS are so potent that they produce symptoms of autism even without the help of Candida Albicans and heavy metals. All collected experiments on the following website involve laboratory mice injected with only LPS and exhibiting the same symptoms as those in ASD.

LPS induces a depressive syndrome, characterized by anhedonia, anorexia, body weight loss, and reduced locomotor, exploratory, and social behavior. This result has been replicated so many times by different research studies that the names, “Sickness Behavior” and “Endotoxemia” are now applied to this condition. [5][6][7]

The mission of this website is to collect and display links to some of the available research articles from PubMed, a service from the National Library of Medicine and the National Institute of Health, that link LPS to the varied and diverse symptoms of ASD. We were able to find and collect experiments for almost every possible neurological and biological symptom of ASD in order to prove that most symptoms of ASD, have a corresponding experiment on Medline that proves each is a symptom of LPS toxicity.

The articles on this website are just a tiny fraction of the available research The amount of evidence is overwhelmoing, for example, performing a search for “hippocampus lps”, in PubMed will retrieve 222 citations.

The number of similarities between ASD and LPS toxicity is sufficiently impressive to demand attention and cannot be ignored. The following are symptoms of LPS poisoning; these symptoms are also found in children with autism:

Tesla_WTC_Solution
24th April 2014, 20:08
p.s. got cut off

BRAIN

Reductions in oligodendrocyte or myelin markers
A marked cerebral cytokine response
White matter injury
Changes in amygdala
Change in dopamine and serotonin levels
Reduction of blood flow to the brain
Changes in blood-brain barrier permeability for large (protein) molecules
Increased the number of pyramidal and granular cells in the hippo-campus

EMOTIONS AND BEHAVIOR

Anxiety
Depression
Reduction in social behavior
Lack of social interaction
Increase in addiction
Lack of exploratory behavior

DIGESTIVE

Weight loss
Breakage and depletion of microvilli
The tight junctions widen and become disrupted.
IBS and IBD
Gut inflamation
Leaky Gut
Digestive symptoms
Disrupted Intestinal Transit
LPS is linked to the problems of gluten,soy and dairy in ASD children

IMMUNE FUNCTION

Increase in TNF alpha.
Increases in certain NK cells and monocytes
Increases in lymphocytes

OTHER

Low Levels of Thyroid
Low Levels of Glutathione
Low Levels of Amino Acids
Impairment of Bile Flow
Increasing the Number of Viable Candida Albicans
An increase in pain sensitivity

Researchers at the UC Davis M.I.N.D. Institute found clear differences in cellular responses between autistic children and neurotypical children following exposure to LPS, bean lectin and bacterial agents. At the Institute this was discovered to be a major and important difference between children with ASD and typical children.[8]

HEPARAN SULFATE IN BRAIN DEVELOPMENT

http://upload.wikimedia.org/wikipedia/commons/thumb/4/40/Heparan_sulfate.png/440px-Heparan_sulfate.png


Sci. STKE, 11 November 2003
Vol. 2003, Issue 208, p. tw436
[DOI: 10.1126/stke.2003.208.tw436]

EDITORS’ CHOICE
DEVELOPMENTAL BIOLOGY Heparan Sulfate in Brain Development
Heparan sulfate binds to a number of growth factors and morphogens and is highly expressed in the developing mammalian central nervous system (CNS). In order to elucidate heparan sulfate’s role in brain development, Inataniet al. selectively knocked out heparan sulfate synthesis in the developing mouse CNS. Mutant mice exhibited malformations in specific regions of the brain that corresponded to disrupted distribution of fibroblast growth factor and decreased cell proliferation. Axon pathfinding in the brain and retina was also disrupted, pointing to additional regulatory functions of heparan sulfate.

M. Inatani, F. Irie, A. S. Plump, M. Tessier-Lavigne, Y. Yamaguchi, Mammalian brain morphogenesis and midline axon guidance require heparan sulfate. Science 302, 1044-1046 (2003). [Abstract] [Full Text]

Citation: Heparan Sulfate in Brain Development. Sci. STKE 2003, tw436 (2003).

“ASK NOT WHAT YOUR COUNTRY CAN DO FOR YOU…”
_________________________________________________________

Heparan sulfate
From Wikipedia, the free encyclopedia
Heparan sulfate (HS) is a linear polysaccharide found in all animal tissues. It occurs as a proteoglycan (HSPG) in which two or three HS chains are attached in close proximity to cell surface or extracellular matrix proteins.[1][2] It is in this form that HS binds to a variety of protein ligands and regulates a wide variety of biological activities, including developmental processes, angiogenesis,blood coagulation and tumour metastasis. HS has been shown to serve as cellular receptor for a number of viruses including the respiratory syncytial virus (Hallak et al. 2000)

_________________________________________________

“…BUT WHAT YOU CAN DO FOR YOUR COUNTRY.”
___________________________________________________

The Heparan Sulfate-Fibroblast Growth Factor Family: Diversity of Structure and Function
Wallace L. McKeehan,
Fen Wang,
Mikio Kan
Center for Cancer Biology and Nutrition Albert B. Alkek Institute of Biosciences and Technology, Department of Biochemistry and Biophysics, Texas A & M University Houston, Texas 77030
Available online 14 May 2008.
The fibroblast growth factor (FGF) receptor complex is a ubiquitous regulator of development and adult tissue homeostasis that bridges the peri-cellular matrix and the intracellular environment. Diverse members of the FGF polypeptide family, the FGF receptor tyrosine kinase (FGFRTK) family and the FGF receptor heparan sulfate proteoglycan (FGFRHS) family combine to result in active and specific FGFR signal transduction complexes. Regulated alternate splicing and combination of variant subdomains give rise to diversity of FGFRTK monomers. Divalent cations cooperate with the FGFRHS to conformationally restrict FGFRTKtrans-phosphorylation, which causes depression of kinase activity and facilitates appropriate activation of the FGFR complex by FGF. Diffusional and conformational molecular models of the oligomeric FGFR complex are presented to explain how different point mutations in the FGFRTK commonly cause craniofacial and skeletal abnormalities of graded severity by graded increases in FGF-independent activity of total FGFR complexes. The role of the FGF family in liver growth and function and in prostate tumor progression is discussed.

Copyright © 1998 Academic Press. Published by Elsevier Inc. All rights reserved.

_________________________________________________________

Performing your original search, “heparan sulfate” glutamate, in PubMed will retrieve 33 records.
Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):5052-6. Epub 2012 Mar 12.
Autism-like socio-communicative deficits and stereotypies in mice lacking heparan sulfate.
Irie F, Badie-Mahdavi H, Yamaguchi Y.
Source
Genetic Disease Program, Sanford Children’s Health Research Center, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA.

Abstract
Heparan sulfate regulates diverse cell-surface signaling events, and its roles in the development of the nervous system recently have been increasingly uncovered by studies using genetic models carrying mutations of genes encoding enzymes for its synthesis. On the other hand, the role of heparan sulfate in the physiological function of the adult brain has been poorly characterized, despite several pieces of evidence suggesting its role in the regulation of synaptic function. To address this issue, we eliminated heparan sulfate from postnatal neurons by conditionally inactivating Ext1, the gene encoding an enzyme essential for heparan sulfate synthesis. Resultant conditional mutant mice show no detectable morphological defects in the cytoarchitecture of the brain. Remarkably, these mutant mice recapitulate almost the full range of autistic symptoms, including impairments in social interaction, expression of stereotyped, repetitive behavior, and impairments in ultrasonic vocalization, as well as some associated features. Mapping of neuronal activation by c-Fos immunohistochemistry demonstrates that neuronal activation in response to social stimulation is attenuated in the amygdala in these mice. Electrophysiology in amygdala pyramidal neurons shows an attenuation of excitatory synaptic transmission, presumably because of the reduction in the level of synaptically localized AMPA-type glutamate receptors. Our results demonstrate that heparan sulfate is critical for normal functioning of glutamatergic synapses and that its deficiency mediates socio-communicative deficits and stereotypies characteristic for autism.

PMID:
22411800

[PubMed - indexed for MEDLINE] PMCID:

PMC3323986 [Available on 2012/9/27]

____________________________________________________________

The role of heparan sulfate and TLR2 in cytokine induction by hepatitis B virus capsids
Vanlandschoot P, Leroux-Roels G.

Bron: J Immunol. 2005 Nov 15;175(10):6253; author reply 6253-5.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342043/

Front Immunol. 2012; 3: 79.
Published online 2012 April 18. doi: 10.3389/fimmu.2012.00079
PMCID: PMC3342043
The Role of TLR2 in Infection and Immunity
Laura Oliveira-Nascimento,1,2 Paola Massari,1 and Lee M. Wetzler1,*
Author information ► Article notes ► Copyright and License information ►
Go to:
Abstract
Toll-like receptors (TLRs) are recognition molecules for multiple pathogens, including bacteria, viruses, fungi, and parasites. TLR2 forms heterodimers with TLR1 and TLR6, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive immunity to pathogens and protection from immune sequelae related to infection with these pathogens. This review will discuss the current status of TLR2 mediated immune responses by recognition of pathogen-associated molecular patterns (PAMPS) on these organisms. We will emphasize both canonical and non-canonical responses to TLR2 ligands with emphasis on whether the inflammation induced by these responses contributes to the disease state or to protection from diseases.

Keywords: TLR2, TLR1, TLR6, TLR2 ligands, polymorphisms, co-receptors
__________________________________________

Talent hits a target no one else can hit; Genius hits a target no one else can see.

—Arthur Schopenhauer
.


Genius is a talent for producing something for which no determinate rule can be given,
not a predisposition consisting of a skill for something that can be learned by following some rule or other.

—Immanuel Kant

Hervé
25th April 2014, 15:21
Another scam to add on top of the scams' pyramid:

THE GOVERNMENT’S DEMONIC STRATEGY AGAINST PARENTS OF AUTISTIC CHILDREN (http://jonrappoport.wordpress.com/2012/09/14/the-governments-demonic-strategy-against-parents-of-autistic-children/)
by Jon Rappoport (http://jonrappoport.wordpress.com/author/jonrappoport/) September 13, 2012

Let me start with this controversial statement: The worst thing parents can do is obtain a diagnosis of autism for their vaccine-damaged child.

The primary fact to keep in mind is: the government must deny any link between vaccines and autism, because to admit the connection would force it to pay out gigantic sums of money to parents, under its Vaccine Injury Compensation Program (VICP).

VICP was created in 1988, through an agreement between the US government and pharmaceutical companies, to funnel all law suits for damage away from those companies, and into a bureaucratic maze of government madness, where the parents’ chances of compensation are minimal, where the deck is most assuredly stacked against them.

National Vaccine Injury Compensation Program (http://www.hrsa.gov/vaccinecompensation/index.html)

Vaccine Adverse Event Reporting System (VAERS) (http://vaers.hhs.gov/index)

Once parents enter the maze, hoping to gain funds to care for their children, they are immediately confronted with a list of disorders and diseases. This list essentially tells them:

“If your vaccine-damaged child has been diagnosed with any of the following medical conditions, you may be able to win financial support. If not, you’re out of luck.”

Autism isn’t on the list. Here is the list:

Vaccine Injury Table (http://www.hrsa.gov/vaccinecompensation/vaccinetable.html)

Can things be any clearer than that? A diagnosis of autism is a trap.

One: a young child receives a vaccine.

Two: he suddenly withdraws from life.

Three: a doctor makes a diagnosis of autism.

Four: the parents want to sue the company that makes the vaccine, but they can’t; they must apply to the VICP for funds to care for their child for the rest of his life.

Five: as soon as they enter the VICP system, they learn that the label “autism” is the very thing that will keep them from the funds they desperately need.

That is the long and short of it.

Forget about the fact that the parents never wanted to involve themselves with a federal government program. They wanted to sue the vaccine maker. They wanted a court award. But they were barred from suing.

At this point, you might say, “But if their child really does have autism and it was obviously caused by a vaccine, then they should be able to find justice somehow.”

You don’t understand how deep this deception goes. You don’t understand how criminally insane it is.

Because, you see, the label of “autism,” the very label that keeps parents from getting help for their children, is an arbitrary word that means nothing.

A deviously designed word that means nothing is keeping parents in a lifelong state of desperation, as they go bankrupt trying to care for their vaccine-damaged child.

We begin here: all 297 official mental disorders, listed in the (DSM) publication of the American Psychiatric Association, are defined and approved by committees of psychiatrists. Whether it is schizophrenia or autism or ADHD or clinical depression or bipolar disease, the definitions consist wholly of described behaviors. That’s all.

Psychiatrists will tell you these symptomatic behaviors are signs of underlying chemical imbalances or genetic aberrations, but they have no tests to back up this assertion. Therefore, all they are left with are the behaviors, their own menu-like clusters of those behaviors, and the “mental disorder” label they place on each cluster.

If they had more, if they had blood tests or brain scans or genetic assays, they would publish those tests and claim they are definitive for diagnoses of mental disorders. But they don’t.

Here is an exchange between a respected psychiatrist and a PBS interviewer, which occurred during a Frontline report titled, “Does ADHD Exist?”

PBS FRONTLINE INTERVIEWER: Skeptics say that there’s no biological marker—that it [ADHD] is the one condition out there where there is no blood test, and that no one knows what causes it.

BARKLEY (Dr. Russell Barkley (http://www.russellbarkley.org/), professor of psychiatry and neurology at the University of Massachusetts Medical Center): That’s tremendously naïve, and it shows a great deal of illiteracy about science and about the mental health professions. A disorder doesn’t have to have a blood test to be valid. If that were the case, all mental disorders would be invalid…There is no lab test for any mental disorder right now in our science. That doesn’t make them invalid. [Emphasis added]

Yes, it actually DOES make all those disorders invalid, unless “science” suddenly means “the opinions of psychiatrists sitting in a room, collecting together various human behaviors, and labeling them.”

Here is a link to the official psychiatric definition of autism disorder. It’s worth reading:

https://www.firstsigns.org/screening/DSM4.htm

Notice that all the criteria for an autism diagnosis are behavioral. There is no mention of laboratory tests or test results. There is no mention of chemical imbalance or genetic factors.

Despite public-relations statements issued by doctors and researchers, they have no laboratory findings to establish or confirm an autism diagnosis.

But, people say, this makes no sense, because children do, in fact, withdraw from the world, stop speaking, throw sudden tantrums. Common sense dictates that these behaviors stem from serious neurological problems.

What could cause the behaviors listed in the official definition of autism disorder?

Vaccine injury; a toxic medical drug; a head injury; ingestion of a poison; an environmental chemical; a severe nutritional deficit; oxygen deprivation at birth; perhaps the emotional devastation accompanying the death of a parent…

There are many possible causes of the behaviors arbitrarily called autism.

However, then, why bother to say “autism?” Why not just say vaccine injury or head injury? Why not try to find the crucial event that brought on a specific child’s sudden and unique withdrawal from the world?

The answer should be clear. By establishing a label like autism, medical drugs can be sold. Studies can be funded. An industry can be created.

Something more can be done, too. The government can reject vaccine injury as a defining event in a child’s life, and reject the need to pay out compensation for it.

The government can say, “Since we know that some children who are diagnosed with autism have not received vaccines, or have not received vaccines containing a neurological poison (mercury), we do not compensate parents whose children are vaccine-injured on the basis that they have autism.”

Poof. It all goes away. Did you catch the sleight-of-hand trick?

Let me expose it. A child is given a vaccine. The child goes into a massive withdrawal from life and communication. A doctor, assessing the child’s behaviors, connects them with the official menu of behaviors labeled “autism.” The doctor then says, “This child has autism.”

Then the parents try to obtain government compensation through the VICP, the Vaccine Injury Compensation Program.

The parents, who now have alarmingly high expenses for ongoing care of their vaccine-damaged child, go to the VICP and say, “Our child has been diagnosed with autism, and we want to collect funds for the vaccine-injury he sustained.”

The government replies, “This is impossible. You see, we know that autism isn’t caused by vaccine injury. We know it because many children who are diagnosed with autism have never been injured by vaccines. Some autistic children have never had vaccines.”

Do you see what is going on here? The parents stepped into a fatal trap. They said “autism” and the government said “vaccine injury does not cause autism.”

You might think the parents could back up and regroup. They could say, “We don’t care what you call it, we just know our child was severely damaged by a vaccine, and we need funds.”

But it’s not as easy as that. The government has no category called “vaccine damage.” The government demands some disease or disorder that is diagnosed and officially attributed to a vaccine injury. As I established earlier, the government has a specific list of diseases or disorders that it will allow—to even begin thinking about financial compensation.

But, you say, this is an evil word game. Of course it’s a word game. The whole notion of “autism” based on no definitive tests was a word game to begin with.

What is called autism (merely a label) is not one condition caused by one factor. It is a loose collection of behaviors that can be caused by various traumas.

Parents say, “My child’s life was stolen away from him. He must have autism.”

A label provides some measure of relief for the parents. It doesn’t prove that the label actually means something. In fact, the label can be a diversion from knowledge that would actually help the child. Suppose, for example, after receiving the DPT vaccine, the child went into a screaming fit and then withdrew from the world. Calling that autism tends to put the parents and the child in the medical system, where there is no definitive effective treatment. Outside that system, there might be some hope with, say, hyperbaric oxygen treatments, or other strategies.

If all this creates a sense of outrage in you, you are not alone.

If a hundred thousand parents of children who have been devastated by vaccines traveled to the headquarters of the Vaccine Injury Compensation Program, at the Parklawn Building, 5600 Fishers Lane, Rockville, Maryland, and if they stayed there and Occupied the area, and if they had a unified position that cut through the word game and the purposeful official delusion, perhaps this criminal insanity would end.

A doctor’s diagnosis of autism most assuredly does not end the insanity. It adds to it.

I once had a conversation with a parent whose child was vaccine-injured and then diagnosed with autism. She spent years trying to obtain compensation from the VICP and failed. Here is a paraphrase of how our conversation went:

“I found out my child wasn’t the point of the VICP proceeding at all. The government’s attorney was doing everything possible to deny us compensation. I felt I was up against a monster.”

“They denied you benefits because your son had been diagnosed with autism?”

“Yes. They said there was no established connection between the vaccine-damage and autism, so they rejected my claim.”

“So you see that the the label ‘autism’ was the very thing they used to reject your claim.”

“I know it now. I didn’t know it then.”

“You also know there is no reason to use the ‘autism’ label. It’s an arbitrary word.”
“It’s a word that is ruining us.”

“Do you realize that, if your doctor had diagnosed your son with a different catch-all label, you would have stood a better chance of gaining compensation?”

“What label?”

“Encephalopathy, for example.”

“So you’re telling me it was all a game, and if I could have gotten the doctor to understand that, he might have written a different diagnosis in my son’s chart, and my chances [of compensation] might have improved.”

“That’s right. A different word.”

In a just world, a parent whose child is damaged by a vaccine would be permitted to sue the vaccine maker. In a less just world, the parent would be able to enter the VICP system and claim a right to compensation based on the simple stand-alone fact that her child was damaged by a vaccine.

In the world we live in, that parent has to prove her child was diagnosed with a condition that the government admits could be caused by a vaccine.

And if the doctor wrote down the word “autism,” the chances of compensation are suddenly very, very remote. They’re zero, unless the parent was able to obtain an accompanying word like “encephalopathy.”

Finally, people will insist that researchers are getting closer to discovering the true and basic cause of autism. This is just more arbitrary verbiage. The “symptoms” listed as definitive for autism are just a collection of behaviors. I could put together a list, and so could you:

“Fatigue, eye flutters, sadness, lack of desire to participate in school, loss of appetite, halting communication…” I could give these behaviors a name, “Remoteness Syndrome,” and call it a disorder, and then I could raise a few billion dollars to search for the underlying cause…but there would be no underlying single cause, because the list was a non-starter. It was just an arbitrary collection of behaviors.

“Autism” is nothing more than a catch-all phrase that indicates a variety of possible unconnected neurological insults. Each patient should be examined by a health practitioner who can really find the cause in that case. Then, perhaps, a treatment plan can be devised for that child.

Meanwhile, the government and its VICP program embroils parents and works them over and tortures them for years, and dumps most of them out on the street with no compensation.

Jon Rappoport

Tesla_WTC_Solution
25th April 2014, 18:37
Thanks for posting this. Very sad but necessary.

Hervé
1st May 2014, 20:44
Are Genetically Engineered Foods Promoting Autism? (http://www.responsibletechnology.org/autism)




http://vimeo.com/42733474
http://vimeo.com/42733474

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Follow the discussion on Twitter using hashtag #gmoautism (https://twitter.com/#%21/search/realtime/%23gmoautism)

By Jeffrey M. Smith

International bestselling author and filmmaker Jeffrey M. Smith is the executive director of the Institute for Responsible Technology www.ResponsibleTechnology.org (http://www.ResponsibleTechnology.org) and a leading spokesperson on the health dangers of GMOs. His books include Seeds of Deception and Genetic Roulette, and his films include Hidden Dangers in Kids’ Meals, Your Milk on Drugs—Just Say No!. For a list of thousands of products that have been verified as non-GMO, go to www.NonGMOShoppingGuide.com (http://www.NonGMOShoppingGuide.com), or download the iPhone app ShopNoGMO (http://itunes.apple.com/app/shopnogmo/id393454798?mt=8).

Download the Autism booklet Click here (http://www.responsibletechnology.org/media/docs/autism_booklet.pdf)
The Autism booklet can be read below, followed by full references:

Are Genetically Engineered Foods Promoting Autism? (http://www.responsibletechnology.org/autism)

“It appears there is a direct correlation between GMOs and autism.” --Arden Anderson, MD, PhD, MPH

Physician Jennifer Armstrong admits, “Twenty years ago, I didn’t even know what the word autism meant. It was rare.” But then something shifted. Whether it was the food, medicine, environment, or some combination, by 2008, an astounding 1 in 54 boys suffered from autism spectrum disorder (ASD) in the US [1]. What is it that is damaging the health and well-being of so many of our children? Don Huber, PhD, professor emeritus from Purdue University, has an idea.

In October 2011, Dr. Huber gave a talk in Germany about the physiological, neurological, and behavioral symptoms of pigs, cows, and rats fed genetically modified (GM) feed. After his lecture, a physician and autism specialist approached him and said, “The symptoms you describe are exactly what we are finding in our autistic children.”

The animals in those studies were fed the same GM soy and corn eaten by children and adults in the US. Both crops are outfitted with bacterial genes that allow them to survive being sprayed with herbicide, which kills plants. As a result, higher residues of toxic weed killer end up inside our food. In addition, some GM corn varieties have an even more unsettling characteristic: their inserted genes produce an insect-killing poison called Bacillus thuringiensis (Bt) toxin in every cell—and in every bite. Although the biotech seed companies like Monsanto claim that their genetically modified organisms (GMOs) are harmless, that’s not what the independent scientists are finding.

Agitated, antisocial animals
When Dr. Huber visited an ongoing research project utilizing rats, he said those animals fed non-GMO feed were “as passive as can be. You can take them out. You can put them on your lap. Treat them almost like a pet cat.” Not so with the rats eating genetically engineered food: “You can hardly catch the rats that have received the GMO feed for a month and a half to two months,” he said. “They go off by themselves. They’re irritated. Crawl up the cage. . . . [They] don’t get along with each other.”

Farmers are reporting the same thing with pigs raised on GMO corn. According to Dr. Huber, a farmer told him that “his pigs just seem to be always irritated. They can’t get along with the other pigs.” Veterinarian Don Skow described similar odd behavior in the pigs of his client. “They would get cannibalistic. They would consume each other—ear biting and tail biting.” And when put in nurseries after weaning, he says, some “would get a condition like Alzheimer’s. They would lose the ability to know where the feed was. A lot of them would die.” Although many of these odd behaviors had been dismissed as normal stress responses for confined animals, when farmers switched to non-GMO feed and the problems went away, the real cause became obvious.

Similar antisocial patterns that Huber described were observed by a Dutch college student more than a decade ago when comparing mice fed GMO or non-GMO soy and corn. He wrote, “The mice fed on GM food seemed less active while in their cages. The differences in activity between the two cages grew as the experiment progressed.” The differences were most striking when he moved the mice to weigh them: “The mice from the GM cage were noticeably more distressed by the occurrence than the other mice. Many were running round and round the basket, scrabbling desperately in the sawdust, and even frantically jumping up the sides, something I’d never seen before. They were clearly more nervous. . . . For me this was the most disconcerting evidence that GM food is not quite normal.”[2]


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Dr. Irina Ermakova, PhD, a senior researcher at the Russian Academy of Sciences, reported to the European Congress of Psychiatry in March 2006 that male rats fed GM soy exhibited anxiety and aggression, while those fed non-GMO soy did not [3]. Ermakova reported the same behavior in GM soy-fed female rats and their offspring in her study published in Ecosinform. The animals “attacked and bit each other and the worker."[4]

(Far more shocking, however, was that more than 50% of the offspring from the GMO-fed group died within three weeks when compared with a 10% death rate among the group fed natural soy. The GM group also had high rates of infertility and had smaller members.)

Autism and gastrointestinal problems
A disproportionate number of autistic children have digestive ailments, suggesting that it plays a significant role in the disease [5]. A Harvard study in 2010, for example, stated that “Gastrointestinal disorders and associated symptoms are commonly reported.”[6] An earlier Harvard and Mass General Hospital study [7] found that most autistic children whom they examined had some type of GI symptom, food allergy, or absorption problem. A 2006 study found that “A history of GI symptoms was elicited in 70% of children with ASD compared with 28% of children with typical development.”[8]

The relationship between digestive health and autism is controversial. What is undeniable, however, is that numerous healthcare practitioners report greater success when they address the gastrointestinal disorder as part of their autism treatment protocol. For some, gastrointestinal intervention is their primary intervention.

Distressed intestines
The many GI disorders in autistic kids [9] include inflammation, intestinal permeability, [10] and imbalances in the intestinal bacteria. [11] These also appear to plague animals fed GMOs. According to Dr. Huber, for example, “When you look at the intestine on those pigs fed the GMO feed, the lining is deteriorated and the critical microbial balance is drastically changed.”

We’ll first examine the damage to the gastrointestinal tract.

According to some butchers who’ve done the comparison, the small intestines in GMO-fed livestock are typically thin and can tear easily as they’re removed from the carcass. The same organ from a non-GMO fed animal, they say, is much stronger. In fact, meat processors in the US typically import intestinal sausage casings from New Zealand, since the quality of the intestines in US livestock is too poor.

Dan Skow, who has treated farm animals for more than 40 years, confirms that after GMOs were introduced in the mid-1990s, he saw a much higher incidence of ileitis, which is inflammation or infection in the ileum (lower part of the small intestine). “Looking at microscopic slides of the intestinal tract,” he says, “there’s definitely something [that] has changed. Whether or not we can actually pinpoint that to the GMO grain thing, I personally think it is.”

Howard Vlieger, an Iowa agricultural consultant, also discovered problems. He asked a slaughterhouse to set aside the stomachs of two sets of pigs he sent for slaughter—one group was fed GMOs and the other non-GMOs. The stomachs of the GMO-fed group were inflamed and ulcerated.

Danish farmer Ib Borup Pedersen also found dramatic changes in his 450-pig operation after switching from GMO soy to non-GMO soy in April 2011. In the previous two years, he had lost 36 sows from ulcers and bloat. Since non-GMO soy was introduced, he had no deaths from these digestive ailments. In the previous year, two pigs died of loss of appetite. None died since the change. And within two days of switching to non-GMO soy, his massive problems with diarrhea virtually disappeared. Both diarrhea and bloat are common symptoms of autistic children.

(In addition to improved digestion, the overall health of Pedersen’s pigs improved, antibiotic use dropped by more than half, milk production increased, conception rate was significantly higher, and average litter size was up.)

One of the earliest indications that GMOs might cause GI tract distress was a 1999 study published in the Lancet. After rats were fed experimental GMO potatoes for just 10 days, the cells of the stomach lining and intestines were significantly altered.[12]


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When California pediatrician Michelle Perro reviewed the study in 2011 and saw the photos of the increased cellular growth and abnormal architecture, she thought to herself, “Uh oh -- we’ve got some problems.” Based on her experience treating children for 30 years, she said, “You can extrapolate that the same thing may be occurring in babies clinically. They are not digesting their food. They are malabsorbing. . . . And I’m seeing that commonly now.” Digestive issues are skyrocketing among her patients.

She’s not alone. According to US hospital discharges and ambulatory admissions records data, inflammatory bowel disease in the US population skyrocketed by 40% since the introduction of GMOs. Dr. Perro strongly suspects that GMOs are a major contributor.

Family practitioner Myrto Ashe agrees: “We know food allergies are on the rise and also diseases related to common foods, like celiac disease. Patients report that dairy products make them wheeze, or tomatoes give them joint pains. It’s as though our food is harming us,” she says. “Something is happening. And if the intestines are playing a big role, and I’m getting the sense they are, then any change in our diet becomes a suspect.”

Holes in our gut
A connection to GMOs became an increasing concern when Dr. Ashe was asked to give a presentation on the health risks of GMOs to a mothers’ group in California. “To prepare for this,” she said, “I reviewed a lot of literature and tried to see what mechanisms are supported by the most solid scientific research. And to me, it was this intestinal permeability.”

Dr. Ashe explains: “Once intestinal permeability increases, then it’s possible for larger bits of food to go though—bits that really should have been digested fully before getting assimilated. Once these go into the bloodstream, the body can react to them, and this reaction is an immune reaction. . . . I think anything that can increase intestinal permeability is a huge danger. The same diseases that research suggests are connected to intestinal permeability are the diseases that seem to be on the rise.”

Numerous doctors point to holes in the gut walls as responsible for a long list of diseases and disorders. Although this notion is not yet at the forefront of mainstream medical understanding for these diseases, there have been books, medical conferences, and professional practices all devoted to the concept.

Physician Gary Gordon puts it simply: “If you buy a brand new car and it says that it’s meant to run on gas and you go and put diesel in it, you could expect it won’t go very far. . . By making your intestine leaky, we are permitting building blocks to go into our body that are the wrong fuel.”

Pesticide-producing corn may be the culprit
When considering intestinal permeability, concern about the Bt-toxin in GMO crops looms large. This poison is designed to create holes (pores) in the digestive tract of insects. That is how it kills them.[13]

The Environmental Protection Agency (EPA), which labels Bt corn and Bt cotton plants as registered pesticides, insists that Bt-toxin will have absolutely no influence on human or mammalian cells. But research published in the Journal of Applied Toxicology [14] this past February proves them wrong. Researchers “documented that modified Bt toxins [from GM plants] are not inert on human cells, but can exert toxicity.” In high concentrations (generally higher than that produced in average Bt corn), Bt-toxin disrupts the membrane in just 24 hours, causing certain fluid to leak through the cell walls. The authors specifically note, “This may be due to pore formation like in insect cells.” Thus, Bt-toxin may indeed create small holes in our intestines.

Dr. Gordon warns, “If is causing an increased propensity for our intestine to become permeable or leaky and for foods to be presented to our bloodstream in a premature fashion, the havoc that it will cause will be across the entire spectrum of disease, from premature aging and Alzheimer’s to Parkinson’s to autism to cancer to asthma.”

Numerous professionals believe that Bt toxin produced in corn is already accelerating many diseases in the US. Arden Andersen, DO, PhD, MPH, believes Bt toxin is specifically implicated in the development of autism.

[B]Compromised flora
In addition to structural deformities in the digestive tract of autistic kids, many also point to intestinal flora that’s gone wild. The bacteria living inside us play an important role in digestion, immunity, detoxification, and even the production of nutrients. In fact, the number of these bacterial cells in our digestive system is about 10 times the number of cells in our entire body. There’s an emerging health field dedicated to restoring the proper balance of intestinal microorganisms.

There is also growing evidence that animals fed GMOs have an improper balance. Dr. Huber says the pigs fed GMOs have a “very dramatic difference in the microflora.” He says it “has a terrible odor to it compared to the normal microflora because of that changed bio environment.” Some farmers that butcher their own livestock also report that GMO-fed pigs and cows have a horrible stench and discolored organs.

Dan Skow says that the balance of the good bacteria inside livestock has been thrown way off. “Now what set this off and why these disruptions of the balance to the microscopic flora in the intestinal tract? I’m personally suspicious—there’s a lot of impact from the GMOs.” Dr. Skow, like many others, is not willing to make an ironclad determination that GMOs are the causative factor. “There needs to be a lot more work to verify this,” he says. But that hasn’t stopped him from strongly urging his clients to switch to non-GMO animal feed. And when they do, he sees a difference in both the health and behavior of their livestock.

The German physician who approached Dr. Huber is also convinced enough to make changes in his autistic patients. When he understood the connection with altered gut bacteria, he responded: “I now know exactly where I have to look, and why when I could modify the diet of an autistic child 10 years ago and have a very excellent response for remediation and recovery, why I’m not getting that response now. We are no longer able to change that microflora back—because we’re continuing to feed GMO-contaminated food to our children.”

Botulism
There are several ways that GMOs might be causing problems in our gut bacteria, all of which are unsettling. The first is that most of the genetically engineered crops are “herbicide tolerant"; they end up with much higher levels of poisonous weed killer concentrated in the food portion of the plant. The two main weed killers, Roundup and Liberty, both have antibacterial properties. In other words, they can kill bacteria. According to Dr. Huber, the active ingredient in Roundup (glyphosate) is even patented as a microbiocide to kill intestinal microorganisms. This can have serious consequences.

Dr. Huber describes German research demonstrating that even tiny amounts of Roundup in a cow’s diet can kill beneficial bacteria that normally control the growth of botulism. He and others believe that the overuse of Roundup, especially on Roundup Ready crops, is the likely reason for an apparent rise in botulism poisoning in livestock -- and possibly humans.[15] (And low levels of botulism are also implicated as a possible contributor to sudden infant death syndrome.) [16]

Dead sheep, buffalo, and cows
A second reason why GMO crops may interfere with gut bacteria has been proposed by renowned Indian biologist P. M. Bhargava, PhD. In India, farmers allow sheep, goats, and buffalo to graze on cotton plants after harvest. While the animals had no negative reactions year after year, when genetically engineered Bt cotton was introduced into the country, the results were tragic. Thousands of animals died. Numerous others suffer from a variety of disorders.[17]

These animals are called ruminants. They all have a compartment in their digestive tract where specialized bacteria break down the cellulose before it travels on to be digested and assimilated.

Dr. Bhargava believes that the Bt-toxin produced in every cell of the cotton plant kills the cellulose-digesting bacteria normally found in the rumen. This would explain why autopsies of the dead sheep revealed shriveled intestines. According to Bhargava, since the cellulose was never broken down, the food never made it into the intestines.

Similar evidence was found in a village near Warangal, India. All 13 of their buffaloes died after grazing for just a single day on Bt cotton plants. When I interviewed the villager who assisted with the autopsy of one of the animals, he reported that there was still undigested food in the rumen—three to four days after consumption.

US agriculture consultant Marc Tainio reports another story that might be related. His client was raising miniature cattle, only three feet high. When the client switched to GMO corn feed, the animals “weren’t able to process the food correctly, and they would bloat up and die.” The farmer quickly lost about 90% of his herd. He was able to save the rest by switching back to non-GMO corn.

If Bt-toxin kills rumen bacteria, it may not be a problem for us humans since we don’t have rumens. On the other hand, we do have gut bacteria, and the Bt toxin may interact with those bacteria in some way to cause harm. This appears to be the case in insects: a study demonstrated that Bt-toxin only killed certain insects when their gut bacteria were present. When the bacteria were removed by administering antibiotics, the toxin was no longer lethal. The authors suggest that Bt-toxin can cause “otherwise benign gut bacteria to exert pathogenic effects.”[18] The mechanics of how this happens, and whether it also impacts humans, is not known.

GMOs “stick to the ribs”
The only human GMO feeding study ever published does show interactions with our intestinal flora. The implications of this research are quite serious. British scientists found that part of the DNA inserted into GMO crops can actually transfer into the DNA of our gut bacteria.[19] Specifically, part of the Roundup Ready gene normally found in Monsanto’s soybeans had taken up residence within the intestinal flora of three out of seven subjects tested. The transfer did not occur in the lab. It had apparently taken place after consuming GM soy in some previous meal(s). And these subjects lived in the UK, where the intake of GM soy is a small fraction of what is eaten in the US.

The study was published in Nature Biotechnology in 2004. It was condensed from a larger, more detailed study. The published version left out a significant fact: the gut bacteria that contained part of the Roundup Ready gene was not killed when exposed to Roundup’s active ingredient, glyphosate. These people had Roundup Ready gut bacteria! This suggests that the transferred genes may continue to function inside us. In other words, we may have GM proteins continuously produced inside our intestines long after we stop eating GMOs.

There are insufficient studies on the GMO soybeans’ Roundup Ready protein to know what exactly its impacts might be on our health. One study, recommended by the World Health Organization (WHO) as part of its recommended allergen screening protocol for GMOs, looks to see if any portion of the protein’s amino acid sequence is similar to a sequence that is known to elicit an allergic response. Unfortunately, Roundup Ready soybeans fail the WHO* test. The protein has a section that is quite similar to that of a dust mite allergen. Therefore, if people who are allergic to dust are also reactive to the Roundup Ready protein, their immune system may be continuously triggered if that protein is produced within their intestines. *Since the WHO criteria were just suggestions, Monsanto chose not to remove their soy after this risk was discovered.

Living Pesticide Factories Inside Us
A more dangerous scenario would be if the Bt-gene produced in Monsanto’s corn were to transfer to our gut bacteria. If so, it might convert our intestinal flora into living pesticide factories. With the inside of our intestines continuously exposed, Bt-toxin might erode the integrity of our GI tract, leading to widespread gut permeability and dysfunction.

In addition, many studies implicate Bt-toxin as an allergen. In its natural state derived from soil bacteria, Bt-toxin has triggered immune responses in farm workers [20] and allergic- and flu-like symptoms in hundreds of exposed citizens.[21] It also evoked immune responses [22] (and intestinal tissue damage) [23] in mice. Similarly, an Italian government study showed that mice fed Bt-corn had dramatic immune responses.[24] And thousands of Indian farm workers who harvest Bt cotton are also experiencing allergic- and flu-like symptoms.[25]

Thus, Bt-toxin production within our intestines might simultaneously trigger immune responses, compromise our digestive tract, and expose the blood to undigested food (which may further trigger immune responses).


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And now the bad news:
a 2011 Canadian study conducted at Sherbrooke Hospital discovered that 93% of the pregnant women they tested had Bt-toxin from Monsanto’s corn in their blood. And so did 80% of their unborn fetuses.[26]

The toxin is likely to wash out of our blood fairly quickly. If that is the case, how can we explain why more than 9 out of 10 women had it circulating? It must be that the intake of Bt-toxin must be very frequent. But Canadians don’t eat that many corn chips and tortillas. They do eat lots of corn derivatives like corn syrup, but these highly processed foods no longer have the Bt-toxin present.

The authors of the study speculate that the source of the Bt-toxin in the blood must have been the meat and dairy of animals fed Bt corn. This assumes that the Bt-toxin protein remains intact through the animals’ entire digestive process and then again through the humans’ digestive process after they eat the meat or dairy.

A more plausible explanation may be that Bt-toxin genes transfer from corn chips or tortillas into our gut bacteria. The active genes then produce the poison on a continuous basis inside the intestinal tract, which then gets into our blood. And for pregnant mothers, the toxin then travels through the placenta into their fetuses.

Precaution
There are numerous theories about autism. Many blame vaccines, others say it’s genetic. The theories are not necessarily mutually exclusive as autism may be caused by several factors.

The link between autism and GMO consumption is by no means verified. Numerous studies would be required to confirm or disprove such a connection. But those won’t happen anytime soon.

Scientists who discover adverse health dangers are routinely attacked and often gagged or fired. The journal Nature describes these “strikes . . . launched from within the scientific community” as sometimes “emotional and personal,” and which can even “accuse scientists of misconduct.”[27] And according to insiders around the world, they successfully suppress the much needed research.

But that hasn’t stopped numerous healthcare professionals from prescribing non-GMO diets to their patients. Indeed, the American Academy of Environmental Medicine urges all doctors to do so. And they also recommend that practitioners distribute educational materials that describe the risks and suggest ways to avoid GMOs.[28]
The LIA (Lyme Induced Autism) Foundation, which looks at Lyme disease and autism, has similarly urged the elimination of 100% of all GMOs from the diets of those suffering from these diseases.[29] Numerous autism education programs also caution against GMOs.

Whether or not GMOs are ultimately linked to autism, animal feeding studies already implicate them in numerous other disorders. Under the sway of the biotech industry, most governments ignore these findings. And no government yet monitors the health impacts of GMO consumption on the health of their citizens.

There are nine GM food crops: soy, corn, cotton (used for cottonseed oil), canola, sugar beets (used in most US sugar), Hawaiian and Chinese papaya, some zucchini and yellow crook neck squash, and alfalfa (used for hay). To make it easier to avoid GMOs, the Institute for Responsible Technology (IRT) offers a list of thousands of products that have been verified as non-GMO at www.NonGMOShoppingGuide.com (http://www.NonGMOShoppingGuide.com) or via a free iPhone app ShopNoGMO (http://itunes.apple.com/app/shopnogmo/id393454798?mt=8). To avoid GMOs, you can use the guide, look for non-GMO labels, buy organic products, or avoid any of the at-risk crops or their derivatives (which are also listed in the Guide).

To better understand the impacts of GMOs on health, the Institute is collecting case studies of humans, livestock, and pets taken off (or put on) a GMO diet. The stories collected so far are compelling. Please share yours by emailing healthy@responsibletechnology.org (healthy@responsibletechnology.org).

The first case study related to autism is summarized below, and it provides some good news. Safe eating.

Case Study
Laura’s son Phillip is autistic. And her experience tells her that dietary interventions—including avoiding GMOs—are the key to recovery. She first noticed a huge improvement when she took her son off of gluten (a protein in wheat and other grains) and casein (a protein in milk). Then she started converting his diet to organic. “Once we moved to organics,” she said, “I really believe that it helped him . . . it’s like another layer was removed that prevented him from really being interested in other children and connecting with other children — playing.”

By introducing organic foods, not only did Laura start using foods that were free of synthetic chemicals, but organic producers are also prohibited from using GMOs. After switching to a mostly organic diet, she estimated that her son was 80% recovered.

“For the longest time, we were stuck in kind of a plateau,” she said, “where he had about an 80 percent recovery.” When people asked her what she did to bring that about, she would respond, “Well, he’s gluten free, he’s casein free, and we are 80 percent organic.” After about the third or fourth time she used those same words, she made the connection. “I’m using the same number . . . like 80 percent recovered, 80 percent organic.” At that point, she realized she needed to go 100% organic.

“It made a huge difference.” She said that in just six months “he has become much more social, much more caring, empathetic, [and] plays with other children.” And his recovery rate? “We call it pretty darn close to 100%. . . . We know that it has to do with what he is eating and what he is not eating.” Laura is now careful to never feed him any GMOs. And she and her husband also follow a non-GMO diet.

It is clear that this single experience is not sufficient to draw wider conclusions. Please share yours. Email healthy@responsibletechnology.org (healthy@responsibletechnology.org).


References

Special thanks to Andrea Lalama for her pioneering investigations into the link between Bt-toxin and autism.

[1] Morbidity and Mortality Weekly Report (MMWR) (http://www.cdc.gov/mmwr), Prevalence of Autism Spectrum Disorders — Autism and Developmental Disabilities Monitoring Network, 14 Sites, United States, 2008, March 30, 2012 / 61(SS03);1-19

[2] Hogendoorn H. Genetically Modified Corn (Zea mays) and Soya (Glycine soja) or Their Natural Varieties - Do Mice Have a Preference?

[3] Ermakova IV. Diet with the Soya Modified by Gene EPSPS CP4 Leads to Anxiety and Aggression in Rats. 14th European Congress of Psychiatry. Nice, France, March 4-8, 2006.

[4] Ermakova IV. Genetically modified soy leads to the decrease of weight and high mortality of rat pups of the first generation. Preliminary studies. Ecosinform. 2006;1:4–9.

[5] http://www.autismbiomed.com/gut-diet.html

[6] Buie T et al. Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: a consensus report. Pediatrics. 2010 Jan;125 Suppl 1:S1-18.

[7] Buie T, Winter H, Kushak R. Preliminary findings in gastrointestinal investigation of autistic patients. 2002. Summary: Harvard University and Mass General Hospital

[8] Valicenti-McDermott M, McVicar K, Rapin I, Wershil BK, Cohen H, Shinnar S. Frequency of gastrointestinal symptoms in children with autism spectrum disorders and association with family history of autoimmune disease. J Dev Behav Pediatr. 2006 Apr;27(2 Suppl):S128-36.

[9] Wasilewska J, Jarocka-Cyrta E, Kaczmarski M. [Gastrointestinal abnormalities in children with autism] [Article in Polish]. Pol Merkur Lekarski. 2009 Jul;27(157):40-3.

[10] de Magistris L, Familiari V, Pascotto A, Sapone A, Frolli A, Iardino P, Carteni M, De Rosa M, Francavilla R, Riegler G, Militerni R, Bravaccio C. Alterations of the Intestinal Barrier in Patients With Autism Spectrum Disorders and in Their First-degree Relatives. J Pediatr Gastroenterol Nutr. 2010 Oct;51(4):418-24.

[11] Wasilewska J, Jarocka-Cyrta E, Kaczmarski M. [Gastrointestinal abnormalities in children with autism] [Article in Polish]. Pol Merkur Lekarski. 2009 Jul;27(157):40-3.

[12] Ewen SW, Pusztai A. Effects of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine. Lancet, 1999;354:1353-1354.

[13] http://www.bt.ucsd.edu/how_bt_work.html (http://www.bt.ucsd.edu/how_bt_work.html)

[14] Mesnage R, Clair E, Gress S, Then C, Székács A, Séralini, GE. (2012). Cytotoxicity on human cells of Cry1Ab and Cry1Ac Bt insecticidal toxins alone or with a glyphosate-based herbicide. J. Appl. Toxicol. doi: 10.1002/jat.2712

[15] Krüger M, Große-Herrenthey A, Schrödl W, Gerlach A, Rodloff A. Visceral botulism at dairy farms in Schleswig Holstein, Germany e Prevalence of Clostridium botulinum in feces of cows, in animal feeds, in feces of the farmers, and in house dust. Anaerobe, in press.

[16] Böhnel H, Behrens S, Loch P, Lube K, Gessler F. Is there a link between infant botulism and sudden infant death? Bacteriological results obtained in central Germany. Eur J Pediatr. 2001 Oct;160(10):623-8. Arnon SS, Midura TF, Damus K, Wood RM, Chin J. Intestinal infection and toxin production by Clostridium botulinum as one cause of sudden infant death syndrome. Lancet. 1978 Jun 17;1(8077):1273-7.

[17] See for example, Mortality in Sheep Flocks after Grazing on Bt Cotton Fields—Warangal District, Andhra Pradesh. Report of thePreliminary Assessment, April 2006. http://www.gmfreecymru.org/pivotal_papers/mortality.htm (http://www.gmfreecymru.org/pivotal_papers/mortality.htm).

[18] Broderick NA et al.. Midgut bacteria required for Bacillus thuringiensis insecticidal activity. Proc Natl Acad Sci USA. 2006, 103:15196-15199. Broderick NA et al. Contributions of gut bacteria to Bacillus thuringiensis-induced mortality vary across a range of Lepidoptera. BMC Biology 2009;7:11. http://www.biomedcentral.com/1741-7007/7/11 (http://www.biomedcentral.com/1741-7007/7/11). Mason KL, Stepien TA, Blum JE, et al. 2011. From Commensal to Pathogen: Translocation of Enterococcus faecalis from the Midgut to the Hemocoel of Manduca sexta. mBio 2(3): doi:10.1128/mBio.00065-11.

[19] Netherwood T et al. Assessing the survival of transgenic plant DNA in the human gastrointestinal tract. Nat Biotech. 2004;22:204-209.

[20] Bernstein IL et al. Immune responses in farm workers after exposure to Bacillus thuringiensis pesticides. Environmental Health Perspectives. 1999;107(7):575–582.

[21] Green M et al. Public health implications of the microbial pesticide Bacillus thuringiensis: An epidemiological study, Oregon, 1985-86, Amer J Public Health. 1990;80(7):848–852. Noble MA, Riben PD, and Cook GJ. Microbiological and epidemiological surveillance program to monitor the health effects of Foray 48B BTK spray (Vancouver, BC: Ministry of Forests, Province of British Columbi, Sep. 30, 1992)

[22] Vazquez et al. Intragastric and intraperitoneal administration of Cry1Ac protoxin from Bacillus thuringiensis induces systemic and mucosal antibody responses in mice. 1897–1912. Vazquez et al. Characterization of the mucosal and systemic immune response induced by Cry1Ac protein from Bacillus thuringiensis HD 73 in mice. Brazilian Journal of Medical and Biological Research. 2000;33:147–155. Vazquez et al. Bacillus thuringiensis Cry1Ac protoxin is a potent systemic and mucosal adjuvant. Scandanavian Journal of Immunology. 1999;49:578–584. See also Vazquez-Padron et al. 147 (2000b).

[23] Fares NH, El-Sayed AK. Fine Structural Changes in the Ileum of Mice Fed on Endotoxin Treated Potatoes and Transgenic Potatoes. Natural Toxins. 1998;6:219–233.

[24] Finamore A et al. Intestinal and Peripheral Immune Response to MON810 Maize Ingestion in Weaning and Old Mice. J Agric Food Chem. 2008;56:11533-11539.

[25] Gupta A et al. Impact of Bt Cotton on Farmers’ Health (in Barwani and Dhar District of Madhya Pradesh). Investigation Report, Oct–Dec 2005. Also, "Bt cotton causing allergic reaction in MP; cattle dead," Bhopal, Nov. 23, 2005.

[26] Aris A, Leblanc S. Maternal and fetal exposure to pesticides associated to genetically modified foods in Eastern Townships of Quebec, Canada. Reprod Toxicol. 2011 May;31(4):528-33. Epub 2011 Feb 18.

[27] Biotech proponents aggressively attack independent research papers: GM crops: Battlefield. Waltz, E., Nature 461, 2009, 27–32; see also Under wraps – Are the crop industry’s strong-arm tactics and close-fisted attitude to sharing seeds holding back independent research and undermining public acceptance of transgenic crops? Waltz, E., Nature Biotechnology, Vol. 27, No. 10, October 2009.

[28] http://www.aaemonline.org/gmopost.html

[29] http://www.lymeinducedautism.com/gmopositionpaper.html

Tesla_WTC_Solution
1st May 2014, 21:05
...Superb, mindblowing, heartbreaking.

Tesla_WTC_Solution
4th May 2014, 03:03
http://edition.cnn.com/2014/04/29/health/irpt-autism-communicating/index.html?hpt=hp_bn8

How Bobby Smith learned to talk at 9, and other autism success stories
Join the conversation
iReport CNN iReport
By Daphne Sashin, CNN
April 29, 2014 -- Updated 1236 GMT (2036 HKT)

Editor's note: April is National Autism Awareness Month. Journalist Ron Suskind's emotional essay in The New York Times Magazine about reaching his son using dialogue from scenes in Disney movies inspired CNN iReport to ask families for their communication strategies.

(CNN) -- Bobby Smith's mother, like all parents, looked forward to the day when her baby could use words to tell her what was wrong. What hurts? Why are you sad?

By the time Bobby turned 7, Cheri Smith was still wondering if that day would ever come.

Her son had been diagnosed on the moderate-to-severe end of the autism spectrum as a toddler. He had ways of conveying his needs -- he'd give Smith or her husband the remote control if he wanted to watch TV, or hand his mom her purse if he wanted to go out -- but there were so many things he couldn't communicate.

He "cannot tell us if something hurts, why he is upset or happy, where he would like to go, what happened at school today, what he would like to do for his birthday, what he would like Santa to bring him for Christmas," Smith wrote on CNN iReport in March 2012. The older he grew, the worse Bobby's behavior was getting. He would fly into rages, which Smith believed were in part the result of his inability to effectively communicate his feelings and to understand what others were telling him.

esperate for help, in April 2012, Smith found a behavioral therapist who would change their family's life. Bobby turns 10 next month and is a totally different boy now, she said.

"She knew that Bobby had the ability to talk," Smith said in a recent update. "She pushed Bobby like none of us had before."

Wherever they fall on the spectrum, people with autism often struggle with communication. They can have trouble developing language skills or fail to understand nonverbal communication through things like eye contact and facial expressions.

Parents, therapists and those with autism themselves described a gamut of communication techniques that have helped. Besides working on actual talking, some have found success with picture card systems, sign language or printed words; others speak through stuffed animals or video game characters.

'Learn to speak our language'

Kat Muir, 26, works as a speech-language pathologist in Indianapolis, bridging the communication gap. Most of the children she works with have Autism Spectrum Disorder -- like herself. Muir was diagnosed with Asperger's Syndrome at age 22 when she was in graduate school and still not making friends.

She was always adept at using words, but was challenged by social communication. It was particularly hard in junior high.

"Girls are expected to know instinctively how to be social, and when they don't, it is very obvious," she said.

For years, she thought of a conversation "as a contest to see who could say the most interesting thing." She remembers one time when some girls were talking about Britney Spears; she jumped in with her own contribution, saying something like, "Planes in World War I had synchronized guns so the gunmen didn't shoot their own propellers off."

No one cared. And they told her so.

It got better when she moved to a big public high school, where students seemed more tolerant of differences. Now she reminds herself to talk about what other people like, not just what she finds interesting.

She said it helps to find an activity "that encourages communication but doesn't force it." For her, that's dance class.

"It's reassuring to know that I will see familiar faces for an hour at the same time every week. I may socialize by starting a conversation about favorite dance moves, or I may exchange smiles with someone because we're doing what we love. The more structured a social interaction is, the more comfortable it is."

To those without autism, said Muir, "Everyone with autism has something to say. Learn to speak our language, and we will learn to speak yours."

Power of a pig

California speech-language pathologist Lois Jean Brady agrees. As a certified autism specialist, she advises parents to use their child's special interests -- animals, music, technology or cars, for instance -- to build their language.

"Go into their world and slowly lead them to yours," she said.

With students who love animals, Brady uses a potbellied pig named Buttercup to communicate. She has found many children feel comfortable talking with an animal and some have said their first words to Buttercup.

She tells the story of a junior high school student who desperately wanted friends. She rehearsed a few answers to "common pig questions" such as "What does he eat?" and "How much does he weigh?" then sent the young man into the school hallway with Buttercup on a leash.

"It was not long before he was surrounded by other students, mostly girls, answering questions with a smile from ear to ear. A couple of the students remained friends," she said.

Brady's own son is on the autism spectrum. He is now 20 years old, goes to college and works with other special needs children. When he was younger, he and his mother would spend hours in the living room, lining up toy cars.

"I kept the cars in a large bucket and if he wanted one he had to ask for it," Brady said. "Initially it was just 'car,' then 'blue car,' then 'shiny blue car,' building language one car at a time."

More cookies?

It has taken about two years for Emily Ferguson's son Sammy to learn to use cards with pictures to communicate. The 8-year-old has severe autism, and speaks about three to seven words a month. He can't tell his mother when he's in pain, and she would give anything to have a conversation with him. But she celebrates that he is able to communicate about 30 food requests and 16 nonfood requests (play, go outside, etc.) through pictures.

"I was tickled when Sammy realized he had no limit to the amount of times he could request cookies. For the first time, I felt like a 'normal' mother, because I had a child who was asking for something he wanted repeatedly, and he was getting the same answer ('No.')," Ferguson wrote in an e-mail.

"It has been an amazing experience to see Sammy go from just crying to using pointing to giving others picture cards on sentence strips."

Ferguson prays Sammy will find the communication tools that work best for him, "and that he will be able to share his thoughts and emotions with those around him. Until that day, I want the world to understand that my child is worth respecting, loving and cherishing."

Talking at 9

Cheri Smith's son, Bobby, knew about 50 words by the time he was 9, but his main form of communication was taking his parents by the hand to what he wanted. A behavioral therapist near their West Virginia home helped Smith understand that their son was physically capable of speaking more, with practice.

For the first six months, therapist Sharon Holbert worked with Bobby on sitting properly in his seat, keeping his hands folded on the table (instead of hitting her) and his feet in front of him (instead of kicking her). There was a close link between behavior and talking: As he learned how to stay calm, he was able to learn more; as he became better at communicating, he grew more relaxed, Holbert said.

"If you have a student who's hitting and screaming and kicking, you can't teach them anything. Once you get them to a place where they're ready to learn, then bam, you can do something," said Holbert, a board-certified behavior analyst. "His ability to learn was there. I think he figured out 'if I hit people, they probably will leave me alone.'"

As they worked on identifying colors, numbers or letters, Holbert wouldn't acknowledge his response as correct unless he said it verbally.

Smith copied the model at home.

"If he wanted any food items, if he wanted a particular TV show that he liked, if he wanted to go outside, he had to ask verbally or he didn't get his want," Smith said. "Quickly it was just easier for him to say the word than it was to throw a fit."

He can now verbally identify letters, colors, animals and some shapes, count up to 20 and say about 100 vocabulary words. He can answer simple questions and has gone from using single words to short sentences like, "I want rice cakes please," or mostly complete sentences like, "I want swim at the beach."

"We went from being a family where our child was physically aggressive and having constant meltdowns to one that is enjoying experiencing the world through Bobby's eyes."

He also has his own unique language, which his parents have come to appreciate, too.

Bobby loves to go for car rides. When he wants his mom to turn down a particular road, "he will put on his own turn signal. He clicks his tongue and makes it sound exactly like a car's turn signal, and that is how I have known where he wants to go."

Tesla_WTC_Solution
4th May 2014, 03:16
http://www.activistpost.com/2014/05/interview-with-arnold-hoekstra-first.html

Thursday, May 1, 2014
Interview With Arnold Hoekstra, First Canadian To Be Fired For Vaccine Refusal
Brandon Turbeville
Activist Post

In my recent article entitled, “First Canadian Fired For Refusing Vaccine,” I wrote about the case of Arnold Hoekstra, the first man in Canada to be fired for refusing to submit to a flu vaccination at his place of employment, the Boundary Hospital in British Columbia.

Hoekstra, who is 49, held a permanent part-time position at the hospital as an adult day program worker. However, when he was instructed to submit to a flu vaccination, he refused to be injected with the toxic cocktail of chemicals and viruses that have been demonstrated to cause a number of adverse health effects in both children and adults. Short of agreeing to be injected with a vaccine that has been shown to be ineffective at preventing the flu (at best), Hoekstra’s only other option was to wear a face mask at all times while at work.

Hoekstra refused this option as well because he claims that wearing a mask all day makes him feel like he is suffocating. Thus, Hoekstra was terminated from his job as a result of his decision.

In my article, I used quotes from Hoekstra as they were presented in other media outlets as well as those that he provided me with in an email interview. Below is the entirety of the email interview between myself and Arnold Hoekstra.

As I wrote previously, social approval and disapproval is often used to enforce a number of tragic policies by using the force of the people who themselves will be further enslaved by them. The recent propaganda push by the pharmaceutical companies and their media mouthpieces is simply the gearing up for a major battle in the future that will inevitably lead to the universal mandate of vaccination applicable to all people with no exemptions.

For now, Arnold Hoekstra stands as one of the first victims of this quiet war.

Brandon: How long had you worked for the Boundary Hospital?

Arnold Hoekstra: 5 yrs

Brandon: How many times had the hospital asked that employees submit to vaccination in the past?

Arnold Hoekstra: Once before in 2012. The ruling was overturned because of union intervention.

Brandon: What was the process used by the hospital in order to encourage employees to vaccinate? What was the language used by management in this regard?

Arnold Hoekstra: They used notices throughout the hospital giving their reasoning for getting the shot [and] posted notices in the office, gifts, br[ought]the vaccine to the work site and personally ask[ed] me if I was going to have the shot on more than one occasion. And advertising on [the] work site online.

Brandon: What are your reasons for refusing to vaccinate?

Arnold Hoekstra: The ingredients [and] Principle. When a choice comes to do or not to do I must trust the true way rather than the way the majority is going. When the masses flock to something, it is, in most cases, the wrong way. Few exceptions.

Brandon: What are some specific issues you have with the vaccine? Does your skepticism extend to vaccinations in general or only the flu vaccine?

Arnold Hoekstra: I believe all vaccinations are harmful. It also puts people in a false sense of security. They try to shortcut their health, deceiving themselves to believe that the professionals know better and that they could not possibly know for themselves.

Brandon: Obviously, your resistance to the dictate to vaccinate was based on the potential adverse health effects that vaccines have demonstrated to produce. But what about the idea that individuals should be free to choose what they put in their bodies? Did that concept influence your decision as well?

Arnold Hoekstra: Yes it did. To my understanding when someone attempts to invade that sacred place (my body) it is a violation.

Brandon: Why did you refuse to even wear the face mask?

Arnold Hoekstra: The main reason I did not wear the mask is because I did not want to exhibit fear. I did not want anyone to think I agreed in any way with this policy. I believe the only reason people wore the masks wasn't because they believed it was going to be affective or that the policy in general was right but that they would be disciplined for not doing so.

Also, I believe that it was used to label those who didn't get the shot as uncooperative. And l believe it was coercive in the way that those who wouldn't have taken the flu shot, did so in order to avoid wearing it for 4 months of the "flu season."

Brandon: Do you plan to take any legal action against the hospital?

Arnold Hoekstra: That is a hard question to answer. The hospital is run by a governing authority (Interior Health) B.C. They are responsible for firing me.

Who is ultimately responsible? You have to work your way up the ladder. Follow the money. It doesn't take a genius to figure out the rest.

To answer the question about what to do legally ... My main goal is for health professionals or, for that matter, anyone to be able to choose for themselves what they want in this matter and [to] not to be put in this position.

If legal action will stop the madness then my answer is yes.

Do I believe I should be compensated? Yes. They forced me into this position. I could not go against my conscience. They did not consider me as an individual or listen to the reason for my decision to not comply.

Brandon: Do you regret your decision?

Arnold Hoekstra: I do not regret my decision. I regret that the powers that be made this awful choice.

Brandon: Do you think your case is indicative of what is to come? Do you think we will see more people lose their jobs as a result of their refusal to submit to vaccinations?

Arnold Hoekstra: I believe the screws will continue to tighten until the whole nation is on board. They have said in the media that they want the percentage of health care workers taking the shot to go much higher than 80 percent.

As far as people losing their jobs ... well I hate to say it but most people tend to do what they’re told, regardless of the fact that they are putting their health at risk. Many I talked to disagreed with the policy but because of fear of discipline and losing their jobs. They just complied.

Brandon: If you could say one thing to the people who may be hearing about your case for the first time, what would it be?
[B]
Arnold Hoekstra: Think for yourself. Don't allow others - no matter how many degrees they have to the right of their name - to think for you. And always remember that you always have a choice.

Brandon Turbeville is an author out of Florence, South Carolina. He has a Bachelor's Degree from Francis Marion University and is the author of six books, Codex Alimentarius -- The End of Health Freedom, 7 Real Conspiracies, Five Sense Solutions and Dispatches From a Dissident, volume 1 and volume 2, and The Road to Damascus: The Anglo-American Assault on Syria. Turbeville has published over 300 articles dealing on a wide variety of subjects including health, economics, government corruption, and civil liberties. Brandon Turbeville's podcast Truth on The Tracks can be found every Monday night 9 pm EST at UCYTV. He is available for radio and TV interviews. Please contact activistpost (at) gmail.com.

Napping
4th May 2014, 04:33
Hi Tesla and other contributors,

I must confess, I'm struggling to find the time to be able to carry out sufficient research to gain a sufficient grasp of the vaccination Autism spectrum debate.

I'm a recent dad, I'm doing a masters degree whilst working full time and my wife is also studying full time…so we're pretty time poor.

I've seen enough evidence in a whole range of high level conspiracies to establish that people in high places don't necessarily have the publics best interests at heart. I see it as highly conceivable that vaccinations may indeed be causing some nasty autoimmune/neurological/who knows what reactions, temporary and permanent in children and that the government/transnationals/whoever stands to gain/lose from this issue is not revealing all that is known re the consequences of vaccinations.

With my young child approaching her first hit of the MMR vaccine, I'd like to know more, but just can't wade through mass of papers, blogs, videos etc.

Could I ask a big favour to those who have dedicated some serious hours in this issue and point me towards the strongest high level empirical evidence that indicates a link between vaccinations and autism and the like. Any particularly powerful documentaries etc would be great also.

Based on all of the evidence, are the consequence of not vaccinating i.e. infectious disease outbreaks still too severe to consider not maintaining herd immunity. In other words, if the odds are say 1 in 100 (extremely high odds) for a bad reaction to vaccinations, on the whole, is it still a necessary evil to vaccinate?

For what it's worth, my current stance is that there are characteristics amongst a minority of individuals who appear to react poorly to vaccinations for host of different reasons. I think that this number is still relatively low, but is still there, despite denial from government and health groups for fear of litigation and fear of loss of herd immunity. I believe more needs to be done to identify a subset of characteristics that make individuals vulnerable to a bad reaction to vaccinations with measures put in place for a safe alternative or to simply not vaccinate those individuals.

This stance is based on a fraction of the knowledge you guys have acquired, so I'd be keen to hear your opinion and the key data to back those opinions up.

Apologies if this has already been done previously - happy to be redirected.

Cheers,

Napping

Tesla_WTC_Solution
4th May 2014, 20:02
Since there is a link to allergies, we need to be looking at the mechanism of the proteins on cell surfaces, for starters, when looking at autism.
People think they are going to find a "gene" for it, some factor other than vaccination allowing them to use the word "because" -- but science is coming up empty.


I read two or three years ago that scientists still do not fully understand the mechanism behind the interactions between Hepatitis B and the substance Heparan Sulfate, for example. How can scientists say that a certain vaccine is harmless, when they don't even understand what happens between the body and the germ itself in the first place?


http://www.ncbi.nlm.nih.gov/pubmed/18046710

Hepatitis B virus infection initiates with a large surface protein-dependent binding to heparan sulfate proteoglycans.
Contrary to many other viruses, the initial steps of the hepatitis B virus (HBV) infection, including attachment to hepatocytes, specific receptor interactions, and membrane fusion, are unsolved.

HBV infection requires the initial attachment to the carbohydrate side chains of hepatocyte-associated heparan sulfate proteoglycans as attachment receptors. This interaction initializes the multistep entry process of HBV and cannot be bypassed by alternative routes.

Simulated autism symptoms in mice by affecting Heparan Sulfate:


http://www.ncbi.nlm.nih.gov/pubmed/22411800
Autism-like socio-communicative deficits and stereotypies in mice lacking heparan sulfate.

Heparan sulfate regulates diverse cell-surface signaling events, and its roles in the development of the nervous system recently have been increasingly uncovered by studies using genetic models carrying mutations of genes encoding enzymes for its synthesis. On the other hand, the role of heparan sulfate in the physiological function of the adult brain has been poorly characterized, despite several pieces of evidence suggesting its role in the regulation of synaptic function. To address this issue, we eliminated heparan sulfate from postnatal neurons by conditionally inactivating Ext1, the gene encoding an enzyme essential for heparan sulfate synthesis. Resultant conditional mutant mice show no detectable morphological defects in the cytoarchitecture of the brain. Remarkably, these mutant mice recapitulate almost the full range of autistic symptoms, including impairments in social interaction, expression of stereotyped, repetitive behavior, and impairments in ultrasonic vocalization, as well as some associated features. Mapping of neuronal activation by c-Fos immunohistochemistry demonstrates that neuronal activation in response to social stimulation is attenuated in the amygdala in these mice. Electrophysiology in amygdala pyramidal neurons shows an attenuation of excitatory synaptic transmission, presumably because of the reduction in the level of synaptically localized AMPA-type glutamate receptors. Our results demonstrate that heparan sulfate is critical for normal functioning of glutamatergic synapses and that its deficiency mediates socio-communicative deficits and stereotypies characteristic for autism.



We know that Y Pestis, the black plague of the tales, works against the human body by affecting Cell Signaling.

Well, having problems with Heparan Sulfate in the body, also affects cell signaling.

Many stress disorders and diseases, and even autism, share the common factor of faulty cell signaling.



_______________


Cell signaling adulterations


http://www.thedogplace.org/VACCINES/ImmuneSystem-Impact_Jordan-DVM-107.asp

How Vaccines Dysregulate The Immune System and
Impact Genetic Control Over Disease Expression

5th Annual Joint American Homeopathic Conference Poster Session 2010

presented by Patricia Jordan, DVM, CVA, CTCVH, & Herbology http://dr-jordan.com

Mucosal Immunity

http://www.thedogplace.org/VACCINES/ImmuneSystem-Impact-1_Jordan.gif


Cell mediated responses (Th1) Lymphocytes, (CD1, CD 2, CD3, CD4, CD8) monocytes- macrophages and natural killer (NK) cells (principal components) Cytokines

Humoral responses (Th2) involve soluble components including immunoglobulins (antibodies) [Igs-IgG, IgM, IgA, IgE, IgD], class switching, antibody gamma globulins and complement proteins.

Immune System Components Genetic Major histocompatibility complex (MHC) system Chromosome, gene, haplotype, and polymorphism and super gene family molecules.9 MHC genes and include [HLA-A, HLA-B, HLA-C, HLA-DPA 1, HLADPB1, HLA-DQA1, HLA-DQB1, HLA-DRA and HLADRBI.] MHC region divided into three regions Class I (HLA-A, B and C) Class II (HLADP, DQ and DR) and Class III genes encode complement components (C2, C4 and Factor B), cytokines (TNF-α) MHC genes display high levels of allelic diversity


Activation of Adaptive Immunity Innate immunity may trigger adaptive immune responses thru Antigen processing and presentation by macrophages and dendritic cells .The evolution of the immune system is a direct consequence of pathogen-exerted selection pressure. It is particularly those qualities like progressive development of humoral and cellular adoptive immunity, Major Histocompatibility Complex (MHC), variable class I and class II genes, precise mechanisms of immune recognition and long-term immune memory that reflect the fundamental evolutionary advancement of the vertebrate immune system. In evolution the survival advantage imposed by an extremely reactive immune system is jeopardized if that system turns against the host and causes "self" destruction.

Vaccination is an abnormal pathogen presented in an abnormal route (injection) and influences the entire immune system in an unnatural way, leading to unnatural evolutionary selection where the results are dys regulation of the immune system, disruption of TH1 bias, atrophy of mucosal, increased inflammation, loss of specification and control. Vaccination dysregulates the immune system and genetically impacts the HLA (MHC) leading to an abnormal expression of disease susceptibility. The vaccine is no more a reflection of the actual environmental challenges faced by those vaccinated than the now dysregulated immune system is a reflection of intelligent design or natural selection. Vaccines are genotoxic; corrupted genomes are leading to the loss of the organic self. Vaccines are responsible for autoimmune, cancer, Type I-IV reactions, allergies, asthma, atopy anaphylaxis, eczema, organ failure, neurological, behavioral disease and death.[List is not complete]

http://www.thedogplace.org/VACCINES/ImmuneSystem-Impact-3_Jordan.gif



Anything that affects gene coding affects genetic expression of disease



The evolution of the immune system is a direct consequence of the pathogens the immune system was exposed to from the environment. The pathogens exert an evolutionary selection pressure which was in part responsible for the genotypes of the MHC (major histocompatibility complexes) that developed in tandem to handle the pathogens. The MHC determines the host’s immunopathology impact from the antigen and is responsible for the expression of clinical disease. The immune system is very complex and developed to handle an enormous variety of pathogens, the genetic ability to respond to a large number of pathogens was necessary in order to survive to live another day.



The MHC tissue markers are one of the major routes of tapping into the possible needs for survival via the immune response. Although not the only way, besides the MHC we have the major loci, minor loci and many other locations for gene expression to effect disease expression. We now see the complexity of immune system response pathways and still there are many factors that remain unknown. The MHC and the HLA and DLA (yes, dogs also have MHC sites like the humans) in fact all vertebrates have this important link of genetic expression of antigen reception and engagement. The groups of receptor sites not only engage with the pathogens, they are also responsible for a cascade of events that have evolved over time to express the organism’s impact with a pathogen, reflecting in dis ease susceptibility and genetic expression.



There is a great variability in how any one individual will react to any pathogen and it is the individual’s genetic variability that is the marvel of individual and species survival .Not everyone would respond the same way to each pathogenic impact. The immune system, like a virus has great reach with incredible mutation ability through gene expression and this brings an organism forward to survive another day.



Vaccines lead to genetic mutations. Genetic impact on MHC (HLA) is what dictates genetic expression of disease susceptibility. Vaccines rob the individual of natural evolutionary selection pressures based on natural antigen risks. Vaccines are altering gene sequences, inserting genes, affecting genome and destroying the organic immunologically determined susceptibility that evolved with natural selection. Determined susceptibility is genetically impacted ahead of disease expression by the antigens presented to or encountered by the individual. The immune system has evolved naturally to promote life and what is happening with unnatural antigen environment delivered in unnatural route to dysregulate the immune system is resulting in unnatural selection, immune system corruption and species distortion.



The genetic basis for susceptibility to disease is complex but well before man understood anything about the immune system and how it worked, he intruded on the evolved design with a hubris that is having collateral damage and unintended consequences of species de evolution.

A little immunology review;

The innate immune system was developed to provide the organism with an immediate response. The natural immune system is composed of three portions; the first line of defense is the mucosal immunity and works with the cell mediated immune system (Th1) to deal with the great majority of pathogens. Entry sites to the body via the skin, mucosal sites of the nasal/respiratory, oral/rectal, ocular, aural and urogenital is where the majority of trials for the immune system would have started. The mucosal immunity has antiseptic patches of secretory immunoglobulins (IgA) to respond first. If the mucosal surfaces were actually penetrated than the IgE immunoglobulins came forth for the defense.



The cell mediated responders have evolved to provide the acute inflammation response which is necessary in properly maturing the body’s immune system. Without the majority of pathogens entering from these sites, the immune system does not reach maturity and therefore is unable to respond competently. The childhood xanthamatic diseases fulfill this purpose of immune system maturation. Denied the ability to “mature” the immune system, the organism is left with a dysfunctional immune response and genetic disease expression is altered.



Acute inflammation in the mature immune system can process and effectively clear the intruder. The hypothesis on how this takes place is via the dendritic cells instructions to TH1 polarity. Of course if the dendritic cells are damaged from the vaccine or the aluminum or the mercury in the vaccines, this is one way the vaccines dysregulate the polarity of the immune response. The body needs to be able to focus on the correct form of response as the body deals with the pathogen. Later, after the invasion by pathogen has been cleared, the body then engages the humoral immunity (Th2) to recognize the pathogen and produces antibody against it. This form of the immune system is the acquired immune response which vaccinations were meant to augment. The humoral immunity makes the specific recognizing antibody after the body is over the acute inflammation so as not to exhaust the individual and prevent recovery.



Humoral immunity (Th2) unskewed system is a much different system designed to deal with pathogens or agents that might penetrate the skin bypassing the mucosal immunity ex; venoms from snakebites, poisons or toxins from bites, stings or deep punctures and microbial injection into areas of low oxygenation .The humoral system is capable of handling toxin inactivation and antigen opsonization, dealing with intracellular pathogens and direction of recognition via antibody production. The natural immune system never evolved to see immune challenges enter the body like this. Rarely would a pathogen come into the immune system’s pristine internal environment of the blood. Humoral immunity was not designed to handle a myriad of pathogens this route, rather the humoral immunity is an internal deeper acting immune system for a lesser number of directly injected pathogens. Parental presentation of the pathogens via vaccination was not “good shepherding” practice and instead has been responsible for the improper wiring, signaling and biochemical pathway disruptions that make up many disorders today. Again, the wrench thrown into the dynamics of an evolutionarily successful system by manual manipulations not based on evolutionary pressure but by medical hubris. Although pleased with this intervention, man has remained incapable of understanding the chaos they have created.

The complex immune system with the spread of genetic variability has served us well through the beginning of time. Unfortunately, about 300 years ago an adulteration and violation of the natural workings of the immune system took place. This adulteration was the unnatural injection of unnatural pathogens that were not from the natural environment but rather a concoction of ingredients made artificially and mixed with toxic chemicals. Early on the recipe included embalming agents, later with heavy and light metals, and eventually with genetically engineered chimeras, man made monsters of unnatural origin. Many of the viruses being injected into the bodies are genetically engineered and certainly not organic. The vaccine has never been a natural pathogen of the natural environment and never a natural route of introduction and penetration of the host immune system. Why would we not foresee the dys regulation, dysfunction and the accompanied corresponding genetic compromises and hybridization that explain the growing number of health issues that have run parallel with the rise in vaccine number and use?



The many ways the vaccines dysregulate the immune system and de construct health. First imposition of the vaccine is to affect genetic expression of disease by affording the unnatural engagement of the MHC, the major HLA then minor loci; cytokine genes, CD-encoding genes, T cell receptor genes, growth hormone and immunoglobulin genes any of the polygenes that cascade down to the intricacies of our many possible gene responses.



Second imposition of the vaccine is to skew the immune system and remove the balance of Th1 and Th2 between cell mediated immunity and humoral immunity. Total dysregulation, shifting of the poles of immunity which will include a combination of mutations, gene expression, biochemical pathway alterations, enzyme disruptions, hijacking the system dys regulation by up regulation of the IgE expression and a down regulation of the IgA, disruption of the cytokine profile and many, many other routes depending on the nature of the pathogen and toxins in the vaccine and the variable gene response of the individual.



Expression of disease now, is a function of the unnatural exposure to unnatural pathogens and toxins and the expression of disease as varied as behavioral, Type I-IV Hypersensitivity; allergies, asthma, anaphylaxis, atopy, eczema, cancer, autoimmune, bacterial, viral, yeast, fungal, internal and external parasites and genetic diseases. The genetic expression of disease is predated by the link up of the pathogen and the individual’s gene which are pathogen impact impressionable. The unnatural selection pressure on the species by the use of vaccines is unnaturally evolving or de evolving the species through genotoxicity and genetic disease increase. The genetic damage or “genetic susceptibility” is transferable to the next generation. The next generation when vaccinated, expresses easily the adverse events that vaccines are selecting for.

The type of immune response that occurs after pathogen binding is determined by cytokine messengers that are triggered by certain elements of the pathogen. The vaccine contains a multiple number of ways to affect this: contamination with unknown viruses and microbial components, unnatural pathogens, chimeras and other genetically engineered products, unfiltered genetic pieces like virions, prions, viruses from other species, aluminum, mercury which can directly lead to abnormal cytokine messengers being produced via pathogen alterations/adulterations/mutations. Modified live viruses or “attenuated viruses” allow live cells to migrate to and replicate onto the host’s tissues. Another act of hubris has occurred because playing with viruses all of these last 300 years, it was only recently that science has now discovered that viruses are not dead, they are not live, they are packets of genetic material that when in the presence of a susceptible and permissive living cell that has the necessary receptor can replicate and infect .We have to remember, the virus affects the appearance of antigen recognition sites in our MHC system which evolved as a type of ANTIVIRUS SOFTWEAR SYSTEM.



Sometimes, virus contamination in a vaccine can activate viruses in the human body 30-40 years after inoculation. The presence of unknown viruses, the contamination of viruses, the recombination and reassortment of viral genes and the introduction of xenotropic viruses, infective DNA viruses have all again - due to the hubris of man - introduced disease and pathology into organisms receiving the jab. The process of injecting unnatural substances into the body started well before the identification of the fist virus! The contamination continues today with the filtering process not finding virions and prions and other smaller genetic impacting contaminants. [Rotavirus vaccine for children found to contain pig virus]. The viral and even microbial antigens are all players in the genetic expression of disease and disease susceptibility to every genome via the MHC and other still unidentified pathways.



Adjuvants additionally adulterate the intelligence of the innate immune response. Adjuvants “add” inflammation and pathogen distortion and therefore cell signaling adulterations, impingement upon the evolutionarily perfected system and result in a loss of order. In 1988, Dr. Ron Schultz spoke out in a roundtable discussion over his concerns of the random addition to anything into vaccines without understanding in the least the impact that the addition of for example interleukins into the vaccines. He framed the impact of the whole body or even just the immune system as a complete unknown yet the cavalier attitude from vaccine makers was that no caution was necessary.



We know now that including interleukin in the vaccines in the 1980’s has now produced children born to vaccinated populations with the genetic disease of missing interleukins! The “new” auto inflammatory syndrome DIRA deficiency of interleukin 1 receptor agonist where children display a constellation of serious and potentially fatal systemic symptoms from birth are inherited mutations in IL IRN - a gene that encodes a protein known as interleukin 1 receptor antagonist. The irony that Dr. Ian Tizzard would compare the ability to add ingredients like alum to vaccines used since 1926 and still in l988 not having any idea how it worked, is little comfort to the many parents of children suffering the highest rate of cancer, brain cancer. In 1999 theWHO through the IARC listed the aluminum in vaccines as a grade 3 out of 4 carcinogens. It doesn’t help either to understand now that aluminum will increase the permeability of the blood brain barrier and allow viruses (viruses that have an affinity for the central nervous system like measles) into the brain along with the mercury and aluminum - both metals that can act synergistically to mutate. Seriously, they still don’t see where the rise in childhood brain cancer is coming from?



Aluminum in the vaccines is also up regulating the IgE and compromising the IgA, therefore the presence of aluminum in the vaccines is a much involved gene impactor which causes vaccines to result in allergies, atopy, anaphylaxis, asthma and eczema expression. The natural immune system has a variety of defense tools to use in the protection of the organism however these systems are dys regulated when damaged pathways result from damaged pathogens or genetically engineered pathogens are artificially introduced.

The effects of alum were never known even though the toxin has enjoyed a hierarchical rise in use and success. The amount used in vaccines is not a “safe” amount, it is only the amount they found necessary to exert its inflammatory effect as an adjuvant! The lack of safety studies, lack of teratogenicity or carcinogenic studies or any long term effects signaling genetic defects from vaccines were never done. For any agency from the HHS, CDC, FDA, USDA,WHO, UN, UNICEF, and GAVI to endorse or project vaccines as safe is criminal and investigations should be called for.



Liability waivers put in force for the drug companies to escape prosecutorial litigation will not be upheld in the face of gross criminal action for failure to perform due diligence in the safety study or even of the efficacy studies that are lacking for vaccine use in the first place. The question as to what exactly was known as FDA-licensed products are unleashed upon the public gives rise to another question: why is it that the drug companies that makes vaccines and promotes their use, are the same drug companies that make the drug for the VACCINE DISEASE that follows the vaccine use? What exactly are the revelations that are bound behind “proprietary confidentiality clauses” and is this the way drug companies are pleading the Fifth Amendment for protection from self incrimination? Would this be the reason the governments remove vaccine liability from the manufacturers of the experimental guise under which health care is purported?



The highly polymorphic HLA/DLA antigen systems which are involved in antigen presentation clearly affects responses to vaccination and therefore this impact is unknown in any organism receiving the jab. This lack of knowing makes every vaccination: “experimentation under the guise of health care delivery.” Effects of vaccines on any individual are variable and therefore any expected result incalculable, the risk to any organism is therefore unknown.



Administering a jab is not synonymous with conveying immunity. Antibody production is not equated to immunity and vaccination does not mean immunization. Damage from vaccines are cumulative, cell mediated immune suppression increases significantly with every jab. Multivalent vaccines are particularly damaging and immune disrupting.



Only vaccinated individuals were found to develop auto antibodies in a landmark study done at Perdue University. Auto antibodies are made with the vaccines from the viruses, from the microbial antigens, from the aluminum and mercury and other ingredients that would mutate or disrupt the pathogen. The increase of molecular mimicry increases with vaccines and these examples of pathways to increase the number of auto antibodies formed the trigger necessary to promote genetic expression of autoimmune disease. Certainly, autoimmune disease expression is one step closer to genetic disease and that handicap will transfer vertically to the next generation in many instances. The important understanding is that the adulteration of the genome came in via the injection of vaccine.

Since not even a very heavy book could contain all the pathways to disease expression from genetic effects of the vaccine (the great immune adulterant), let us at least end this with the following understanding; vaccines have no environmental epidemiological studies to support the benefits over risks of vaccine administration, they are not safe nor innocuous and have not even been proven effective in conveying immunity which is the only reason one would consider their use in the first place. Vaccination use fits the definition of “a medical assumption” and according to Dr. Stephen Blake is certainly the biggest medical assumption ever made in the history of mankind and is directly responsible for more disease, death and disability than any other medical procedure or act.



Not surprisingly, with the safety of vaccination questioned and autism, autoimmune diseases and cancer linked in hospitals to vaccinations, only now is the NIH announcing research grants for the purpose of addressing vaccine safety. The Research to Advance Vaccine Safety (R21) is just now in 2010 being initiated to research vaccines:



“research that will contribute to the overall understanding of vaccine safety such as physiological and immunological responses to vaccines and vaccine components, how genetic variations affect immune/physiological responses that may impact vaccine safety and identification of risk factors and biological markers that may be used to access whether there is a relationship between certain diseases or disorders and licensed vaccines and the application of genomic/molecular technologies to improve knowledge of vaccine safety”



The problem is that this “scientific study is too late”. For three centuries genotoxicity, immune dysregulation and immune dysfunctioning - even to immune deficiency and annihilation - has been de evolving the genomes of man and animals.



Dr. Harris Coulter would consider the vaccination as medical hubris and the many diseases spawned from its use the “unintended consequences and collateral damage”. The National Childhood Vaccination Program is a program in which any parent should have the right to protect their child. The mandatory vaccine programs are genetic assaults and project a form of invalid federal medicine which is tyranny. The promotion of the vaccine programs are fraudulent and criminal acts which no taxpayer should be made to support as the effect in many cases, cases rising with the rise in vaccine use, are genetic and constitute genotoxicity.



This attempt to violate the natural laws of evolution is impacting the species in a de-evolutionary format leading to increased genetic expression of disease and forcing those jabbed into a cycle of chronic disease management if not death first. Of course the same drug companies that make vaccines are usually the same ones that sell the medications to palliate and suppress said disease expression. This system of making disease and then making the medications to suppress and palliate the disease puts into the hands of the drug companies all the federal funds that sponsored the vaccines and then the money from the manipulated health care system treating the disease. Soon the allocation of funds for the drug companies will shift the power from the democratic state to the hands of the drug companies that have full impunity from liability, this benefit legislated for them by the members of the democratic legislature elected to represent those being vaccinated into disease and harmed in the first place!


Dr. Harris Coulter stated that” medicine” had a lot more to do with “politics” than it did with “science”. Dr. Patricia Jordan noted that it took a Doctor of Political Science to point out to the medical profession what they did not seem capable of recognizing right in front of their face, that medicine is politics and politics is about money, no science necessary.



Any NIH research done under the Research to Advance Vaccine Safety (R21) must have independent, nonconflict oversight with participation of those harmed by vaccines to ensure that the real measure of vaccine damage is properly addressed. That is, unless the disease, disability and deaths from vaccines were to be immediately stopped in accordance with the Precautionary Principle.



The precautionary principle is a moral and political principle which states that if an action or policy might cause severe or irreversible harm to the public or to the environment, in the absence of a scientific consensus that harm would not ensue, the burden of proof falls on those who would advocate taking the action. The principle aims to provide guidance for protecting public health and the environment in the face of uncertain risks, stating that the absence of full scientific certainty shall not be used as a reason to postpone measures where there is a risk of serious or irreversible harm to public health or the environment.



It is obvious that the unnatural vaccine has unnaturally selected for genes that do not reflect a natural exposure from the real environment and thusly resulted in unnatural selection of genes that have dys regulated the immune system and disrupted the inflammatory pathway and distorted the populations genetically. Unnatural gene selection is then leading to resistance and susceptibility to disease which is unnatural and not the real picture of the antigen state within our external environment for which an immune system is geared to provide survivability against encounter. Vaccination is resulting in abnormal disease expression and the making of disease previously not encountered. Although it is popular to blame our external environment, this is not the main environment our immune system is being pressured by. In the madness, the species are being distorted and genomes are being corrupted. The rise of genetic susceptibility and genetic disease is a reflection of this distortion. Most of what we see today is Vaccine Disease, in that the dysregulation of the immune system by vaccines have altered the genetic susceptibility and expression of disease and is not evolving a better immune system and health but deconstructing the immune system and the genome towards doom.

it even ties in with diseases like arthritis and lupus




http://arthritis-research.com/content/14/6/R243

Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus

Systemic lupus erythematosus is a chronic autoimmune disease characterized by an abundance of autoantibodies against nuclear antigens. Bruton's tyrosine kinase (Btk) is a proximal transducer of the BCR signal that allows for B-cell activation and differentiation. Recently, selective inhibition of Btk by PCI-32765 has shown promise in limiting activity of multiple cells types in various models of cancer and autoimmunity. The aim of this study was to determine the effect of Btk inhibition by PCI-32765 on the development of lupus in lupus-prone B6.Sle1 and B6.Sle1.Sle3 mice.

what is an antigen
http://en.wikipedia.org/wiki/Antigen

In immunology, an antigen (Ag), or antibody generator, is any substance which provokes an adaptive immune response.[1] An antigen is often foreign or toxic to the body (for example, a bacterium) which, once in the body, attracts and is bound to a respective and specific antibody.

what is nuclear antigen
http://en.wikipedia.org/wiki/Proliferating_cell_nuclear_antigen

Proliferating cell nuclear antigen (PCNA) is a protein that acts as a processivity factor for DNA polymerase δ in eukaryotic cells. It achieves this processivity by encircling the DNA, thus creating a topological link to the genome. It is an example of a DNA clamp.

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.[1]

what is a DNA clamp

http://en.wikipedia.org/wiki/DNA_clamp

A DNA clamp, also known as a sliding clamp, is a protein fold that serves as a processivity-promoting factor in DNA replication. As a critical component of the DNA polymerase III holoenzyme, the clamp protein binds DNA polymerase and prevents this enzyme from dissociating from the template DNA strand. The clamp-polymerase protein–protein interactions are stronger and more specific than the direct interactions between the polymerase and the template DNA strand; because one of the rate-limiting steps in the DNA synthesis reaction is the association of the polymerase with the DNA template, the presence of the sliding clamp dramatically increases the number of nucleotides that the polymerase can add to the growing strand per association event. The presence of the DNA clamp can increase the rate of DNA synthesis up to 1,000-fold compared with a nonprocessive polymerase.[2]

what is antibody to nuclear antigen
http://en.wikipedia.org/wiki/Anti-nuclear_antibody

Antinuclear antibodies (ANAs, also known as antinuclear factor or ANF)[1] are autoantibodies that bind to contents of the cell nucleus. In normal individuals, the immune system produces antibodies to foreign proteins (antigens) but not to human proteins (autoantigens). In some individuals, antibodies to human antigens are produced.[2]





maternal antibodies and autism

http://www.medscape.com/viewarticle/807760

Maternal Antibodies May Trigger up to 25% of Autism Cases

Megan Brooks
July 12, 2013


Maternal antibodies that interfere with fetal brain proteins during pregnancy may be responsible for roughly one quarter of cases of autism spectrum disorder (ASD), a new study suggests.

Lead researcher Judy Van de Water, PhD, and colleagues have coined the term "maternal autoantibody–related," or MAR, autism for these cases.

maternal antibodies and autism

http://cat.inist.fr/?aModele=afficheN&cpsidt=14998996
Mechanisms by which maternal antibodies influence infant vaccine responses: review of hypotheses and definition of main determinants


Résumé / Abstract
Several mechanisms have been suggested as mediating the inhibitory influence of maternal antibodies (MatAb) on infant responses. This inhibition is B cell determinant-specific, depends on the ratio between MatAb titers at the time of immunization and the dose of vaccine antigen, and leaves infant T cell responses largely unaffected. Neutralization of vaccine replication or FcγRIIB-mediated inhibitory signalling to infant B cells would not account for these characteristics. In contrast, determinant-specific masking of B cell epitopes and APC uptake of MatAb:vaccine antigen immune complexes, followed by antigen processing and presentation, explain the pattern of pre-clinical and clinical responses to infant vaccines. This allows the definition of the main determinants of the influence of MatAb on infant immunity.

passive immunity

http://en.wikipedia.org/wiki/Passive_immunity


Maternal passive immunity is a type of naturally acquired passive immunity, and refers to antibody-mediated immunity conveyed to a fetus by its mother during pregnancy. Maternal antibodies (MatAb) are passed through the placenta to the fetus by an FcRn receptor on placental cells. This occurs around the third month of gestation.[2] Immunoglobulin G is the only antibody isotype that can pass through the placenta.[2] Immunization is often required shortly following birth to prevent diseases such as tuberculosis, hepatitis B, polio, and pertussis, however, maternal antibodies can inhibit the induction of protective vaccine responses throughout the first year of life. This effect is usually overcome by secondary responses to booster immunization.[3]

Passive immunity is also provided through the transfer of IgA antibodies found in breast milk that are transferred to the gut of the infant, protecting against bacterial infections, until the newborn can synthesize its own antibodies.[4]

Artificially acquired passive immunity is a short-term immunization achieved by the transfer of antibodies, which can be administered in several forms; as human or animal blood plasma or serum, as pooled human immunoglobulin for intravenous (IVIG) or intramuscular (IG) use, as high-titer human IVIG or IG from immunized donors or from donors recovering from the disease, and as monoclonal antibodies (MAb). Passive transfer is used prophylactically in the case of immunodeficiency diseases, such as hypogammaglobulinemia.[5] It is also used in the treatment of several types of acute infection, and to treat poisoning.[1] Immunity derived from passive immunization lasts for only a short period of time, and there is also a potential risk for hypersensitivity reactions, and serum sickness, especially from gamma globulin of non-human origin.[4] Passive immunity provides immediate protection, but the body does not develop memory, therefore the patient is at risk of being infected by the same pathogen later.[4]


The one exception to passive humoral immunity is the passive transfer of cell-mediated immunity, also called adoptive immunization which involves the transfer of mature circulating lymphocytes. It is rarely used in humans, and requires histocompatible (matched) donors, which are often difficult to find, and carries severe risks of graft-versus-host disease.[1] This technique has been used in humans to treat certain diseases including some types of cancer and immunodeficiency. However, this specialized form of passive immunity is most often used in a laboratory setting in the field of immunology, to transfer immunity between "congenic", or deliberately inbred mouse strains which are histocompatible.

vaccines make you likelier to catch diseases:

http://jid.oxfordjournals.org/content/early/2013/04/29/infdis.jit143.long

Waning of Maternal Antibodies Against Measles, Mumps, Rubella, and Varicella in Communities With Contrasting Vaccination Coverage


Conclusions. Children of mothers vaccinated against measles and, possibly, rubella have lower concentrations of maternal antibodies and lose protection by maternal antibodies at an earlier age than children of mothers in communities that oppose vaccination. This increases the risk of disease transmission in highly vaccinated populations.

so they don't even work. might as well not buy them.

vaccines might damage human cells:

http://www.ncbi.nlm.nih.gov/pubmed/12612250

Pediatrics. 2003 Mar;111(3):653-9.
Addressing parents' concerns: do vaccines cause allergic or autoimmune diseases?
Offit PA1, Hackett CJ.
Author information
Abstract


Anecdotal case reports and uncontrolled observational studies in the medical literature claim that vaccines cause chronic diseases such as asthma, multiple sclerosis, chronic arthritis, and diabetes. Several biological mechanisms have been proposed to explain how vaccines might cause allergic or autoimmune diseases. For example, allergic diseases might be caused by prevention of early childhood infections (the "hygiene hypothesis"), causing a prolongation of immunoglobulin E-promoting T-helper cell type 2-type responses. However, vaccines do not prevent most common childhood infections, and large well-controlled epidemiologic studies do not support the hypothesis that vaccines cause allergies. Autoimmune diseases might occur after immunization because proteins on microbial pathogens are similar to human proteins ("molecular mimicry") and could induce immune responses that damage human cells. However, wild-type viruses and bacteria are much better adapted to growth in humans than vaccines and much more likely to stimulate potentially damaging self-reactive lymphocytes. Consistent with critical differences between natural infection and immunization, well-controlled epidemiologic studies do not support the hypothesis that vaccines cause autoimmunity. Flaws in proposed biological mechanisms that explain how vaccines might cause chronic diseases are consistent with the findings of many well-controlled large epidemiologic studies that fail to show a causal relationship.

PMID:
12612250
[PubMed - indexed for MEDLINE]






this is what you need to remember from this post:


because proteins on microbial pathogens are similar to human proteins ("molecular mimicry") and could induce immune responses that damage human cells

Napping
5th May 2014, 12:19
Plenty of info, but I guess my only issue is that the majority of it is anecdotal, or non controlled observational studies that can be heavily influenced by bias. There's enough there to make me think that vaccines do some really bad stuff to the minority of children exposed, but if that minority is really small, even 1 in 1000, don't the consequences of not having people vaccinated far out weigh the minority of people children effected?
Not enough time and money is put towards making vaccines safer. I suppose that would be an admission of guilt so that's not going to happen.

Hervé
5th May 2014, 14:35
Straight from the horse's mouth: Vaccines can't prevent measles outbreaks (http://business.financialpost.com/2014/05/01/lawrence-solomon-vaccines-cant-prevent-measles-outbreaks/)

Lawrence Solomon
Financial Post (http://business.financialpost.com/2014/05/01/lawrence-solomon-vaccines-cant-prevent-measles-outbreaks/)
Thu, 01 May 2014 00:50 CDT


Measles in highly immunized societies occurs primarily among those previously immunized.


http://www.sott.net/image/image/s9/184204/large/vaccine.jpg (http://www.sott.net/image/image/s9/184204/full/vaccine.jpg)

Because different people have different genetic makeups, the vaccine is simply a dud in many, failing to provide the protection they think they’ve acquired.

The recent outbreaks of measles in Canada and the United States came as a shock to many public health experts but they wouldn't have to Dr. Gregory Poland, one of the world's most admired, most advanced thinkers in the field of vaccinology.

The measles vaccine has failed, he explained two years ago in a prescient paper, "The re-emergence of measles in developed countries." In that paper, he warned that due to factors that most haven't noticed, measles has come back to be a serious public health threat. Thankfully, in that paper and elsewhere he also spelled out in no-nonsense fashion what now needs to be done.

Dr. Poland is no vaccine denier. Not only is he among the harshest and most outspoken critics of the "irrationality of the antivaccinationists," he is also one of the strongest proponents for vaccines and the good that they can do. As Professor of Medicine and founder and leader of Mayo Clinic's Vaccine Research Group, one of the world's largest vaccine research organizations; as editor-in-chief of the peer-reviewed scientific journal, Vaccine; as recipient of numerous awards; as chair of vaccine data monitoring committees for pharmaceutical giant Merck; as patent holder in various vaccines processes; as someone who enjoys special employee status with the Centers for Disease Control and the U.S. Department of Defense and as someone who has sat on every federal committee that has dealt with vaccines, no one can accuse him of seeing vaccines from a narrow perspective.

And he sees the need for a major rethink, after concluding that the current measles vaccine is unlikely to ever live up to the job expected of it: "outbreaks are occurring even in highly developed countries where vaccine access, public health infrastructure, and health literacy are not significant issues. This is unexpected and a worrisome harbinger - measles outbreaks are occurring where they are least expected," he wrote in his 2012 paper, listing the "surprising numbers of cases occurring in persons who previously received one or even two documented doses of measles-containing vaccine." During the 1989-1991 U.S. outbreaks, 20% to 40% of those affected had received one to two doses. In a 2011 outbreak in Canada, "over 50% of the 98 individuals had received two doses of measles vaccine."

Dr. Poland noted 15 U.S. outbreaks between 2005 and 2011 and 33 in Europe in 2011 alone, involving more than 30,000 known cases. Meanwhile, the "UK has declared measles once again endemic.... such outbreaks result from both failure to vaccinate, and vaccine failure."

People's failure to get vaccinated is deplorable, Dr. Poland often stresses. But the more fundamental problem stems from the vaccine being less effective in real life than predicted, with a too-high failure rate - between 2% and 10% don't develop expected antibodies after receiving the recommended two shots. Because different people have different genetic makeups, the vaccine is simply a dud in many, failing to provide the protection they think they've acquired.

To make matters worse, even when the vaccine takes, the protection quickly wanes, making it unrealistic to achieve the 95%-plus level of immunity in the general population thought necessary to protect public health. For example, 9% of children having two doses of the vaccine, as public health authorities now recommend, will have lost their immunity after just seven and a half years. As more time passes, more lose their immunity. "This leads to a paradoxical situation whereby measles in highly immunized societies occurs primarily among those previously immunized," Dr. Poland stated.

The measles vaccine's inadequacy doesn't end there, however. It "cannot be administered to those who are immunocompromised, who have allergies to vaccine components, or who are pregnant [among other limitations, leaving] a large enough segment of the population susceptible and unprotected from measles such that cases will continue to occur."

The answer, according to Dr. Poland, lies in our genes. Because of their genetic predisposition, some people will not respond to the current measles vaccine, even with additional boosters. By the same token, the genetic predisposition of others makes them susceptible to harm from the measles vaccine, leading to public wariness, including among the well educated. What is needed, suggests Dr. Poland, is for the public health establishment to accept that the current measles vaccine has so many drawbacks as to make it unworkable, and get on with the job of developing next-generation vaccines.

This next generation vaccine technology, which his Mayo Clinic group is helping pioneer, marries vaccinology with genomics to create personalized, rather than one-size-fits-all, vaccines. Through this new medical discipline of "vaccinomics," a term he dubbed, medical science will not only have the wherewithal to finally achieve the decades-long dream of eradicating measles and other diseases, he believes, but will also do so at lower cost while addressing the concerns of the educated public.

As I will discuss in part two of this series next week, vaccinomics is no pie-in-the-sky fantasy but possibly the next big coming thing, well worth pursuing, and well worth the investment in its development that will be required.

SOTT.net Comment: (http://www.sott.net/article/278506-Straight-from-the-horses-mouth-Vaccines-cant-prevent-measles-outbreaks) Take a look at just ONE of Poland's disclosures (http://www.iceid.org/index.php/general-information/disclosures):
Dr. Gregory Poland wishes to disclose receiving honoraria from Merck for serving as Chair - eDMC and receiving honoraria from Avianax, Dynavax, Liquidia Technologies, Inc., Novartis Vaccines and Diagnostics, PaxVax Inc., and Theraclone Sciences for consulting services. Obviously he is in deep with Big Pharma and they are having a lot of trouble keeping up the vaccine farse [sic]. See also:

-Measles: A rash of misinformation (http://www.sott.net/article/258502-Measles-A-rash-of-misinformation)
-Vaccines Have Serious Side Effects - The Institute of Medicine Says So! (http://www.sott.net/article/235822-Vaccines-Have-Serious-Side-Effects-The-Institute-of-Medicine-Says-So)
-Courts quietly confirm MMR Vaccine causes Autism (http://www.sott.net/article/266747-Courts-quietly-confirm-MMR-Vaccine-causes-Autism)
-Herd immunity: Myth or reality? (http://www.sott.net/article/277282-Herd-immunity-Myth-or-reality)
-FDA document reports autism link after tetanus, pertussis & diptheria vaccine (http://www.sott.net/article/277927-FDA-document-reports-autism-link-after-tetanus-pertussis-diptheria-vaccine)
--------------------------------------------------------------------------------





Because different people have different genetic makeups, the vaccine is simply a dud in many, failing to provide the protection they think they’ve acquired.... thare ya gau!

... blame it on genetics!

Since they have no clue if it's genetics or not, their "Because" is only an authoritative arbitrary that may have nothing to do with the price of fish but, more likely, the latter may be related to "Follow the $$" into Fat Pharma.

Tesla_WTC_Solution
5th May 2014, 20:06
Plenty of info, but I guess my only issue is that the majority of it is anecdotal, or non controlled observational studies that can be heavily influenced by bias. There's enough there to make me think that vaccines do some really bad stuff to the minority of children exposed, but if that minority is really small, even 1 in 1000, don't the consequences of not having people vaccinated far out weigh the minority of people children effected?
Not enough time and money is put towards making vaccines safer. I suppose that would be an admission of guilt so that's not going to happen.

If you
want more
info maybe
help me
find it.

....

Tesla_WTC_Solution
6th May 2014, 01:06
Plenty of info, but I guess my only issue is that the majority of it is anecdotal, or non controlled observational studies that can be heavily influenced by bias. There's enough there to make me think that vaccines do some really bad stuff to the minority of children exposed, but if that minority is really small, even 1 in 1000, don't the consequences of not having people vaccinated far out weigh the minority of people children effected?
Not enough time and money is put towards making vaccines safer. I suppose that would be an admission of guilt so that's not going to happen.

1 in 1000 does not reflect the current autism rate.
what on earth is this crap lol


and how did i miss that part.
you're trying to pull the wool over my eyes or someone has done so to you :(

autism rate in the USA is like 1 in 100.

Which means, if it's vaccine related, gosh -- at least 1 in 100 are affected.

in some towns/states, it's more like 1 in 50.

if you were a school teacher, and 1 in 50 students had a disability so severe they couldn't even wipe their butts or work at Burger King,
wouldn't you want to find out what was happening, even if it meant accepting some "anecdotal" (PC buzzword) or "observational" information as a starting point?




i am SO TIRED of people without kids, people without autistic kids, and people who have never even seen a Measles Mumps or even Rubella case in their whole lives,
telling ME, who has a disabled/retarded child, that the group I belong to (parents with damaged kids) is WRONG.



i am deviating from the research and articles here to engage in petty squabbling, but 1 in 1000??


gifted and talented kids have 10-30 percent more allergies.
meaning gifted children, noble children, children of high intelligence, MORE LIKELY to be damaged by vaccines.



that's Genocide.
and yes I oppose it.

Napping
6th May 2014, 12:35
Tesla and amza, I sincerely appreciate your efforts, but you've basically come up with all I have in my limited searching which is primarily opinion pieces and low level observational studies and anecdotal evidence.

Interesting to note that the mmr is potentially not as full proof as one would like, but it's not overly surprising. The potential of any of these diseases at pandemic levels again is too horrific to risk doing nothing at all imo.

For the record Tesla, I'm not suggesting that autism prevalence is 1 in 1000, a quick search can substantiate that.....I threw that speculative stat out there as a random suggestion of a rate of autism caused by vaccines. That's very different to the overall prevalence of autism. If it was something like 1 in 1000 and it prevented pandemics....I'll have to say i will still take the risk.

What needs to happen though is more research on identifying high risk outliers and safer vaccines.

Personally, I can't see it happening, so at this stage for the sake of "the greater good" I'm leaning towards taking the risk.

Can I also say that I'm truely sorry you've had to go through what you have with your own child and I admire your passion and commitment for answers.

Tesla_WTC_Solution
6th May 2014, 16:58
Tesla and amza, I sincerely appreciate your efforts, but you've basically come up with all I have in my limited searching which is primarily opinion pieces and low level observational studies and anecdotal evidence.

Interesting to note that the mmr is potentially not as full proof as one would like, but it's not overly surprising. The potential of any of these diseases at pandemic levels again is too horrific to risk doing nothing at all imo.

For the record Tesla, I'm not suggesting that autism prevalence is 1 in 1000, a quick search can substantiate that.....I threw that speculative stat out there as a random suggestion of a rate of autism caused by vaccines. That's very different to the overall prevalence of autism. If it was something like 1 in 1000 and it prevented pandemics....I'll have to say i will still take the risk.

What needs to happen though is more research on identifying high risk outliers and safer vaccines.

Personally, I can't see it happening, so at this stage for the sake of "the greater good" I'm leaning towards taking the risk.

Can I also say that I'm truely sorry you've had to go through what you have with your own child and I admire your passion and commitment for answers.

Thanks, I guess :)

Feel free to post some research data along with your opinion.
I see lots of questions and absolutism in your statements but no fact.

Rachel



p.s. who is going to fund the objective studies? the people who damage our kids? LOL the government?

it's easy for people like you to feel like they are "winning" the argument when a crowd of other crooks did it for ya



If you really care about my kid you will care about the truth more than political correctness.


When America found out about Nazi concentration camps, was it through a German scientific research paper?

GET IT?

Napping
6th May 2014, 20:14
I'm not the type of person who would gain any enjoyment from "winning" an argument against a fellow parent who has suffered the way you have with your child, but you don't know me and you're probably used to having to defend your stance against people who argue for the sake of arguing with no sense of empathy..

I'm genuinely concerned about vaccinating my child, but simply can't find anything comclusive re causation between vaccines and adverse effects on a large scale. I've got little doubt it does occur to vulnerable individuals which worries me a lot.

I agree that high level research won't be funded for this issue because of what it may find and that is horrible.

Your last point suggests a new trajectory regarding our covnersation thus far all together and that is that this is being purposefully done by nefarious individuals. I don't believe that is the case. I believe vaccines were introduced with good intensiond, but perhaps I'm naive.

You're right I should hold up my end of the argument with all the evidence that refutes what you're implying, but right now I'm under the pump, which is why I asked you guys in the first place.

Thanks for the chat.

Tesla_WTC_Solution
6th May 2014, 20:25
I'm not the type of person who would gain any enjoyment from "winning" an argument against a fellow parent who has suffered the way you have with your child, but you don't know me and you're probably used to having to defend your stance against people who argue for the sake of arguing with no sense of empathy..

I'm genuinely concerned about vaccinating my child, but simply can't find anything comclusive re causation between vaccines and adverse effects on a large scale. I've got little doubt it does occur to vulnerable individuals which worries me a lot.

I agree that high level research won't be funded for this issue because of what it may find and that is horrible.

Your last point suggests a new trajectory regarding our covnersation thus far all together and that is that this is being purposefully done by nefarious individuals. I don't believe that is the case. I believe vaccines were introduced with good intensiond, but perhaps I'm naive.

You're right I should hold up my end of the argument with all the evidence that refutes what you're implying, but right now I'm under the pump, which is why I asked you guys in the first place.

Thanks for the chat.



well GD it don't give up, keep looking for papers.
I can try to find more too. Some were saved to a hard drive that has been removed from a laptop and unrecoverable.
I think I've researched this for maybe 5 years. Not very well, not organized, but enough to be personally convinced, vaccines can cause harm.


I am not sure about whether it's intentional.
But we know the electric chair and hangman's noose are intentional.
Sterilization is intentional. Lots of people in foreign countries are being intentionally starved.

Is it so hard to believe that USA/EU would have an interest in removing certain genotypes?
That is very far-fetched, but so was Hitler. In fact the reason so many people have trouble believing the WWII stories,
about German and Japanese experimentation on humans, is that they are far-removed from any mainstream concept of decency and humanity.


I actually respect you for giving humans the benefit of the doubt.
But as some of my friends point out, behavior changes a lot under the perception of scarcity.

And the watchword of the age? "Sustainability".




_________________________


In Washington state, for example, the feds had to look into the condition of foster care and funding given to families enrolled with DDD for autism services.
Because the state was refusing help across the board to families with autism.

The same governing body that virtually forces vaccination (or is it CORPORATE MUSCLE behind this and not the state?) is refusing help to damaged kids.







Please consider, just consider (not necessarily believe w. whole heart) that you're better off in the long run without needles in your life.
Your kids have a better chance of having healthy offspring without factors that mess with DNA and gene expression, protein modulation, etc.



Isn't it bad enough to know about the report from CBS, straight from a woman who worked for the vaccine makers?






i know people made fun of this article but the woman was a real expert:


http://www.cbsnews.com/news/vaccines-and-autism-a-new-scientific-review/

and this journalist ended up having to resign because of trouble at work, censorship, interference with investigating.

and Helen says the same thing, there is interference against investigating.



BySharyl AttkissonCBS NewsApril 1, 2011, 7:55 AM
Vaccines and autism: a new scientific review


For all those who've declared the autism-vaccine debate over - a new scientific review begs to differ. It considers a host of peer-reviewed, published theories that show possible connections between vaccines and autism.

The article in the Journal of Immunotoxicology is entitled "Theoretical aspects of autism: Causes--A review." The author is Helen Ratajczak, surprisingly herself a former senior scientist at a pharmaceutical firm. Ratajczak did what nobody else apparently has bothered to do: she reviewed the body of published science since autism was first described in 1943. Not just one theory suggested by research such as the role of MMR shots, or the mercury preservative thimerosal; but all of them.

Ratajczak's article states, in part, that "Documented causes of autism include genetic mutations and/or deletions, viral infections, and encephalitis [brain damage] following vaccination [emphasis added]. Therefore, autism is the result of genetic defects and/or inflammation of the brain."

The article goes on to discuss many potential vaccine-related culprits, including the increasing number of vaccines given in a short period of time. "What I have published is highly concentrated on hypersensitivity, Ratajczak told us in an interview, "the body's immune system being thrown out of balance."

University of Pennsylvania's Dr. Brian Strom, who has served on Institute of Medicine panels advising the government on vaccine safety says the prevailing medical opinion is that vaccines are scientifically linked to encephalopathy (brain damage), but not scientifically linked to autism. As for Ratajczak's review, he told us he doesn't find it remarkable. "This is a review of theories. Science is based on facts. To draw conclusions on effects of an exposure on people, you need data on people. The data on people do not support that there is a relationship. As such, any speculation about an explanation for a (non-existing) relationship is irrelevant."
Helen Ratajczak, author "Theoretical aspects of autism: Causes--A review."

Ratajczak also looks at a factor that hasn't been widely discussed: human DNA contained in vaccines. That's right, human DNA. Ratajczak reports that about the same time vaccine makers took most thimerosal out of most vaccines (with the exception of flu shots which still widely contain thimerosal), they began making some vaccines using human tissue. Ratajczak says human tissue is currently used in 23 vaccines. She discusses the increase in autism incidences corresponding with the introduction of human DNA to MMR vaccine, and suggests the two could be linked. Ratajczak also says an additional increased spike in autism occurred in 1995 when chicken pox vaccine was grown in human fetal tissue.

Why could human DNA potentially cause brain damage? The way Ratajczak explained it to me: "Because it's human DNA and recipients are humans, there's homologous recombinaltion tiniker. That DNA is incorporated into the host DNA. Now it's changed, altered self and body kills it. Where is this most expressed? The neurons of the brain. Now you have body killing the brain cells and it's an ongoing inflammation. It doesn't stop, it continues through the life of that individual."

Dr. Strom said he was unaware that human DNA was contained in vaccines but told us, "It does not matter...Even if human DNA were then found in vaccines, it does not mean that they cause autism." Ratajczak agrees that nobody has proven DNA causes autism; but argues nobody has shown the opposite, and scientifically, the case is still open.

A number of independent scientists have said they've been subjected to orchestrated campaigns to discredit them when their research exposed vaccine safety issues, especially if it veered into the topic of autism. We asked Ratajczak how she came to research the controversial topic. She told us that for years while working in the pharmaceutical industry, she was restricted as to what she was allowed to publish. "I'm retired now," she told CBS News. "I can write what I want."

We wanted to see if the CDC wished to challenge Ratajczak's review, since many government officials and scientists have implied that theories linking vaccines to autism have been disproven, and Ratajczak states that research shows otherwise. CDC officials told us that "comprehensive review by CDC...would take quite a bit of time." In the meantime, CDC provided these links:

Interagency Autism Coordination Committee: http://iacc.hhs.gov

Overview of all CDC surveillance and epi work: http://www.cdc.gov/ncbddd/autism/research.html

CDC study on risk factors and causes: http://www.cdc.gov/ncbddd/autism/seed.html

© 2011 CBS Interactive Inc. All Rights Reserved.

______________________________________________-




tesla says: i care about this issue but refuse to do all the work for you guys. i need more help from you. there is no excuse to let one person do it all lol. i am not the only one here capable of reading an article. let's start learning some new words, people ..... how many years would it take the forum to get up to speed on vaccines?

Hervé
8th May 2014, 00:41
[...]

Your last point suggests a new trajectory regarding our covnersation thus far all together and that is that this is being purposefully done by nefarious individuals. I don't believe that is the case. I believe vaccines were introduced with good intensiond, but perhaps I'm naive.

[...]
Thanks for the chat.

Have a look at this thread: Agenda 21, Vaccines & The Female Of The Species (http://projectavalon.net/forum4/showthread.php?70016-Agenda-21-Vaccines-The-Female-Of-The-Species)

Tesla_WTC_Solution
8th May 2014, 18:23
Opinion and personal note:

Guys,
I believe anything is possible, and any high and low of moral character absolutely possible for humans.

And through science, miraculous AND horrifying things are possible.

It is SO NAIVE to think that scientific breakthrough only works for good!

Seriously, it happened BEFORE. It happened less than 100 years ago.
Why on earth would they stop, given the opportunity to experiment upon and harm innocent people? Please give it thought. Heartfelt, soulful, sincere thought. Set your reputation and beliefs aside for one moment and just consider what science and capitalism and racism are really capable of doing together in our world.

What cruelty nature does not express, we humans often take up the slack -- and although I WANT to trust and believe the med establishment,
similarly to the educational establishment, many untruths are being circulated as the official word.




I RELY on you people to HELP start finding some of this information if you are truly interested in preserving diversity in the human genome. Instead of saying the same old argument over and over, do a deep web search, buy a journal subscription, do something other than repeat the talking heads -- find the truth.

Expand your intelligence and understand the wholeness of the truth.

Hervé
9th May 2014, 16:44
The Vaccine Hoax is Over. Documents from UK reveal 30 Years of Coverup (http://nsnbc.me/2013/05/10/the-vaccine-hoax-is-over-freedom-of-information-act-documents-from-uk-reveal-30-years-of-coverup/)

Andrew Baker ( FFN),- Freedom of Information Act in the UK (http://www.ecomed.org.uk/wp-content/uploads/2011/09/3-tomljenovic.pdf) filed by a doctor there has revealed 30 years of secret official documents showing that government experts have
1. Known the vaccines don’t work

2. Known they cause the diseases they are supposed to prevent

3. Known they are a hazard to children

4. Colluded to lie to the public

5. Worked to prevent safety studies

Those are the same vaccines that are mandated to children in the US.


http://nsnbc.me/wp-content/uploads/2013/05/800px-Smallpox_vaccine-300x198.jpg (http://nsnbc.me/wp-content/uploads/2013/05/800px-Smallpox_vaccine.jpg)


Educated parents can either get their children out of harm’s way or continue living inside one of the largest most evil lies in history, that vaccines – full of heavy metals, viral diseases, mycoplasma (http://www.youtube.com/watch?v=7W4tu5qgaWA), fecal material, DNA fragments from other species, formaldehyde, polysorbate 80 (a sterilizing agent (http://organichealthadviser.com/archives/polysorbate-80-in-swine-flu-vaccines-infertility-in-humans)) – are a miracle of modern medicine.

Freedom of Information Act filed in the US (http://www.bolenreport.com/Mark%20Geier/foiasuit6.htm) with the CDC by a doctor with an autistic son, seeking information on what the CDC knows about the dangers of vaccines, had by law to be responded to in 20 days. Nearly 7 years later, the doctor went to court and the CDC argued it does not have to turn over documents. A judge ordered the CDC to turn over the documents on September 30th, 2011.

On October 26, 2011, a Denver Post editorial expressed shock that the Obama administration, after promising to be especially transparent, was proposing changes to the Freedom of Information Ac (http://www.denverpost.com/opinion/ci_19192188)t that would allow it to go beyond declaring some documents secret and to actually allow government agencies (such as the CDC) to declare some document “non-existent.”

Simultaneous to this on-going massive CDC cover up involving its primary “health” not recommendation but MANDATE for American children, the CDC is in deep trouble over its decades of covering up the damaging effects of fluoride and affecting the lives of all Americans, especially children and the immune compromised. Lawsuits are being prepared (http://www.citizens.org/?p=3041). Children are ingesting 3-4 times more fluoride by body weight as adults and “[t]he sheer number of potentially harmed citizens — persons with dental fluorosis, kidney patients tipped into needing dialysis, diabetics, thyroid patients, etc — numbers in the millions.”

The CDC is obviously acting against the health of the American people. But the threat to the lives of the American people posed by the CDC’s behavior does not stop there. It participated in designed pandemic laws that are on the books in every state in the US, which arrange for the government to use military to force unknown, untested vaccines, drugs, chemicals, and “medical” treatments on the entire country if it declares a pandemic emergency.

The CDC’s credibility in declaring such a pandemic emergency is non-existent, again based on Freedom of Information Act. For in 2009, after the CDC had declared the H1N1 “pandemic,” the CDC refused to respond to Freedom of Information Act filed by CBS News (http://articles.mercola.com/sites/articles/archive/2009/11/24/superstar-cbs-reporter-blows-the-lid-off-the-swine-flu-media-hype-and-hysteria.aspx) and the CDC also attempted to block their investigation. What the CDC was hiding was its part in one of the largest medical scandals in history (http://articles.mercola.com/sites/articles/archive/2009/10/24/cbs-reveals-that-swine-flu-cases-seriously-overestimated.aspx), putting out wildly exaggerated data on what it claimed were H1N1 cases, and by doing so, created the false impression of a “pandemic” in the US.

The CDC was also covering up e financial scandal to rival the bailout since the vaccines for the false pandemic cost the US billions. And worse, the CDC put pregnant women first in line for an untested vaccine with a sterilizing agent, polysorbate 80, in it. Thanks to the CDC, “the number of vaccine-related “fetal demise” reports increased by 2,440 percent (http://www.naturalnews.com/030657_vaccines_miscarriages.html) in 2009 compared to previous years, which is even more shocking than the miscarriage statistic [700% increase].

The exposure of the vaccine hoax is running neck and neck with the much older hoax of a deadly 1918-19 flu (http://foodfreedom.wordpress.com/2011/07/09/bayer-and-death-1918-and-aspirin/). It was aspirin that killed people in 1918-19, not a pandemic flu. It was the greatest industrial catastrophe in human history with 20-50 million people dying but it was blamed on a flu. The beginning of the drug industry began with that success (and Monsanto was part of it (http://www.naturalnews.com/023094_Monsanto_WHO_industry.html)). The flu myth was used by George Bush (http://www.salem-news.com/articles/april012011/1918-flu-jh.php) to threaten the world with “another pandemic flu that could kill millions” – a terror tactic to get pandemic laws on the books in every state and worldwide. Then the CDC used hoax of the pandemic hoax to create terror over H1N1 and to push deadly vaccines on the public, killing thousands of unborn children and others. (CDC will not release the data (http://www.newmediaexplorer.org/sepp/2010/09/19/us_cdc_hides_vaccine_related_miscarriages_recommends_flu_shot_health_supreme_newsgrabs_sunday_19_sep tember_2010.htm) and continues to push the same vaccine.)

The hoax of the vaccine schedule is over, exposed by FOIAs in the UK.

The hoax of the CDC’s interest in children’s lives has been exposed by its refusal to respond to a doctor’s FOIAs around its knowledge of vaccine dangers.

The 1918-19 pandemic hoax has been exposed by Dr. Karen Starko’s work on aspirin’s role (http://cid.oxfordjournals.org/content/49/9/1405.full) in killing people.

And despite refusing to respond to FOIAS, the CDC’s scandalous hoax of a 2009 flu pandemic and its part in creating it, was exposed by CBS NEWS.

And the Obama administration, in attempting to salvage the last vestige of secrecy around what is really happening with vaccines, by declaring agency documents non-existent, has made its claim of transparency, non-existent.

But pandemic laws arranging for unknown vaccines to be forced on the entire country are still in place with HHS creating a vaccine mixture that should never be used on anyone (http://www.salem-news.com/articles/may012012/aclu-flu.php) and all liability for vaccines having been removed (http://foodfreedomgroup.com/2012/09/29/the-vaccine-hoax-is-over-by-andrew-baker/www.youtube.com/watch?v=QQTgv_Vs_tU). Meanwhile, a Canadian study has just proven that the flu vaccine containing the H1N1 vaccine which kills babies in utero, actually increases the risk of serious pandemic flu (http://articles.mercola.com/sites/articles/archive/2012/09/18/flu-shot-increases-flu-illness.aspx).

Americans who have been duped into submitting their children to the CDC’s deadly vaccines, have a means to respond now. People from every walk of life and every organization, must
1. take the information from the UK FOIAs exposing 30 years of vaccine lies, the refusal of the CDC to provide any information on what it knows about those lies, and the Obama Administration’s efforts to hide the CDC’s awareness of those lies, and go to their state legislatures, demand the immediate nullification of the CDC vaccine schedule and the pandemic laws.

2. inform every vet. active duty military person, law enforcement people, DHS agents and medical personnel they know, of the vaccine hoax, for their families are deeply threatened, too, but they may not be aware of it or that they have been folded into agency structures by the pharmaceutical industry (indistinguishable from the bankers and oil companies) that would make them agents of death for their country with the declaration of a “pandemic” emergency or “bio-terrorist” attack. It is completely clear now that the terrorism/bioterrorism structures are scams (http://www.salem-news.com/articles/september242012/homeland-monsanto-wk.php) so that any actions taken to “protect” this country using those laws would in fact be what threatens the existence of Americans.
It was aspirin that killed millions in 1918-19. Now it is mandated and unknown, untested vaccines with banned adjuvants in them that threaten the country with millions of deaths. At the same time, the CDC is holding 500,000 mega-coffins, built to be incinerated, on its property outside Atlanta. Not to put to fine a point on this, but it’s clear now that the CDC should not be involved in any way with public health.

Thanks to the Freedom of Information Act (FOIA), we know that vaccines are not a miracle of modern medicine. Any medical or government authority which insists vaccines prevent diseases is either ignorant of government documents (and endless studies) revealing the exact opposite or of the CDC’s attempts to hide the truth about vaccines from the public, or means harm to the public.

Thanks to the Freedom of Information Act (FOIA), we know the vaccine schedule is a hoax.

The health danger to American children and adults are vaccines.

Andrew Baker, Food Freedom News (http://foodfreedomgroup.com/2012/09/29/the-vaccine-hoax-is-over-by-andrew-baker/)

Documentation
The vaccination policy and the Code of Practice of the Joint Committee on Vaccination and Immunisation ( JCVI): are they at odds? (http://nsnbc.me/wp-content/uploads/2013/05/BSEM-2011.pdf)

Related articles:
Harvard Scientists warn about Epidemic of Side Effects due to Corruption (http://nsnbc.me/2014/02/10/harvard-scientists-warn-about-epidemic-of-side-effects-due-to-corruption/)

‘All Trials’: because no test should go unheralded (http://nsnbc.me/2013/12/08/all-trials-because-no-test-should-go-unheralded/)

Tesla_WTC_Solution
10th May 2014, 07:17
Mindblowingly compiled. Sorry I didn't see this until just now.
I didn't check my threads for new posts !!! eek I am losing it.

my hat is off to you, Amzer Zo.
thank you for helping -- am forwarding this to my spouse.

===

[ Mod-edit: I moved the next five posts in this thread to a new thread, called Do vaccines contribute to autism. Should we vaccinate? (http://projectavalon.net/forum4/showthread.php?71330-Do-vaccines-contribute-to-autism.-Should-we-vaccinate). This present thread has been focused on autism, and presumes that vaccinations are one of the precipitating agents. A debate over whether vaccines are helpful or harmful is a separate debate. -- Paul ]

Hervé
15th May 2014, 01:52
New Paper Provides Convincing Evidence Vaccine Induced Immune Overload and Related Serious Health Issues is Becoming the Norm not the Exception in US Children (http://www.marketwatch.com/story/new-paper-provides-convincing-evidence-vaccine-induced-immune-overload-and-related-serious-health-issues-is-becoming-the-norm-not-the-exception-in-us-children-2014-05-13)
press release
May 13, 2014, 10:15 a.m. EDT

BALTIMORE, May 13, 2014 /PRNewswire/ -- A new peer reviewed paper was published in a recent issue of Molecular and Genetic Medicine (s1:025)(s1:2014) that presents convincing evidence that the rapid increase in the number of vaccines given to US children has now created a state of immune overload in the majority, or close to the majority, of young US children and that this is being manifested by related health issues including epidemics of obesity, diabetes, and autism. The new paper is authored by immunologist J. Bart Classen, MD.

"We have been publishing for years that vaccines are causing an epidemic of inflammatory diseases including diabetes, obesity and autism. However the number of vaccines given to children has continued to rise to a point where we have reached a state of immune overload in roughly the majority of young US children. The new paper reviews the evidence of immune overload and the plethora of different health effects the children are developing because of the immune overload," says Dr. J. Bart Classen, MD.

Dr. Classen's research indicates that the large number of vaccines given to patients is leading to an epidemic of chronic inflammation resulting in epidemics of autoimmune diseases, allergies, and a comprehensive inhibitory response manifesting as obesity and metabolic syndrome.

"The best data indicates that vaccine induced chronic disease is now of a magnitude that dwarfs almost all prior poisoning of humans including poisoning from agents like asbestos, low dose radiation, lead and even cigarettes. Most patients don't even realize that they are suffering from the adverse effects of vaccines. Even more concerning patients and or their parents are being harassed, accused of practicing poor dieting and exercise habits leading to development obesity and diabetes when in fact they suffer from vaccine induced obesity and diabetes," says Dr. J. Bart Classen.

Copies of many of Dr. Classen's papers can be found on the website www.vaccines.net (http://www.vaccines.net/) .

Classen Immunotherapies
SOURCE Classen Immunotherapies, Inc.
Copyright (C) 2014 PR Newswire. All rights reserved

Tesla_WTC_Solution
15th May 2014, 19:12
THANK you for this.
And imagine having reactive hypoglycemia and asthma already,
THEN developing vaccine related pre diabetes on top.

Talk about a ****ed up life. and you guys wonder why with my avatar.

you should see my skin.

Tesla_WTC_Solution
16th May 2014, 20:16
8Adamas8 posted:

http://www.vaccines.net/vaccine-induced-immune-overload.pdf

Abstract
There has been an epidemic of inflammatory diseases that has paralleled the epidemic on iatrogenic immune
stimulation with vaccines. Extensive evidence links vaccine induced immune over load with the epidemic of type 1
diabetes. More recent data indicates that obesity, type 2 diabetes and other components of metabolic syndrome are
highly associated with immunization and may be manifestations of the negative feedback loop of the immune system
reacting to the immune overload. The epidemic of diabetes/prediabetes appears to be accelerating at a time when
the prevalence of obesity has stabilized, indicating that the negative feedback system of the immune system has
been over whelmed. The theory of vaccine induced immune overload can explain the key observations that have
confounded many competing hypothesis. The current paper reviews the evidence that vaccine induced immune
overload explains the disconnect between the increase in prediabetes and nonalcoholic fatty liver at a time when the
obesity epidemic is waning in children.

Hervé
25th May 2014, 10:48
Scientists Link Autism To These Toxic Chemicals During Fetal Development (http://www.collective-evolution.com/2014/05/11/new-study-links-autism-to-toxin-exposure/)

May 11, 2014 by Arjun Walia (http://www.collective-evolution.com/author/arjun/). 63 Comments. (http://www.collective-evolution.com/2014/05/11/new-study-links-autism-to-toxin-exposure/#comments)


http://cdn3.collective-evolution.com/assets/uploads/2014/05/fetus-300x300.jpeg

The cause of autism is still unknown, but we are definitely closer to figuring it out. A new study published in the journal PLOS Computational Biology, from researchers at the University of Chicago revealed that autism and intellectual disability (ID) rates are linked with exposure to harmful environmental factors during congenital development.


“Essentially what happens is during pregnancy… there are certain sensitive periods where the fetus is very vulnerable to a range of small molecules – from things like plasticisers, prescription drugs, environmental pesticides and other things. Some of these small molecules essentially alter normal development. Autism appears to be strongly correlated with rate of congenital malformations of the genitals in males across the country, this gives an indicator of environmental load and the effect is surprisingly strong. The strongest predictors for autism were associated with the environment; congenital malformations on the reproductive system in males.” (1) (http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1003518) - Andrey Rzhetsky, professor of genetic medicine and human genetics at the University of Chicago

The team analyzed data that covered more than one third of the U.S. population. Data from individual states and more than 2,100 counties were used. Fetuses, particularly males, are sensitive to multiple toxins such as environmental lead, medications and a wide variety of other synthetic molecules, like pesticides, mercury and more. Exposure to these toxins during critical stages of development is thought to explain a large portion of congenital reproductive malformations.


“It’s really a very significant study, and should trigger the medical community, the scientific community and the government, looking at this especially interesting avenue for the prevention of autism. We know that one of the ways to show that there is a problem with pollution is to show through the presence of these reproductive defects and we know that there is a relationship between the presence of these defects and the presence of autism related disorders” Dr. Harbut, Providence-St John Environmental Medicine Expert

This isn’t the first time that scientists have linked autism to the environment. In 2009, Hertz-Picciotto and Lora Delwiche of the UC Dais Department of Public Health Sciences analyzed 17 years of state data that tracks developmental disabilities.


“It’s time to start looking for the environmental culprits responsible for the remarkable increase in the rate of autism in California.” (2) (http://www.scientificamerican.com/article/autism-rise-driven-by-environment/) – Irva Hertz – Picciotto, epidemiology professor at University of California, David

Our environment is full of neurodevelopmental toxins, which means they alter how the brain grows. Mercury, polychlorinated diphenyl, lead, brominated flame retardants and pesticides are a few of many examples. Don’t forget about insecticides and herbicides.

Another recent study published in the New England Journal of Medicine compared brain autopsies of autistic children who had died from unrelated causes to those of normal ones. The autistic brains demonstrated abnormal patches of disorganized neurons that disrupted the usual distinct layers in the brain’s cortex. The study suggests that abnormalities occurred in utero during key developmental stages between 19 to 30 weeks gestation. It’s not just the toxin, it’s the timing of the exposure as well.(3) (http://www.nejm.org/doi/full/10.1056/NEJMoa1307491)

In the United States alone, autism rates have risen from 1:10,000 in 1981 to 1:68 in 2014. Again, multiple studies point to the prevalence of toxins in our environment as the culprit, and there are toxins in many things. No doubt about it, we might not be looking at one cause for autism, but multiple factors associated with how we choose to live our lives on a daily basis.

So, let’s take a look at some of these toxins that could be linked to autism and other neurodevelopmental disorders.

One factor I’d like to touch upon first is the fact that autism rates in Europe have remained pretty steady over the last decade. This coincides with the fact that in more than 60 countries around the world, including Australia, Japan, and all of the countries in the European Union, there are significant restrictions or complete bans on the production and sale of GMOs and the pesticides that go with them. In the United States, government agencies have approved massive amounts of pesticides, completely ignoring the fact that they are linked to numerous health ailments. Not long ago, the Environmental Protection Agency (EPA) recently raised the allowable concentrations of Monsanto’s glyphosate, also known as “Roundup” on food crops, edible oils and animal feed (you can read more about that here (http://www.collective-evolution.com/2014/04/17/new-study-finds-roundup-herbicide-to-be-125x-more-toxic-than-regulators-claim/)). Although we don’t know for sure, it’s important to at least consider the large increase in Genetically Modified Organism (GMOs) and the massive amount of chemicals (pesticides and herbicides) that are dumped on them every year. These pesticides have been linked to numerous health ailments.

A group of scientists put together a comprehensive review of existing data that shows how European regulators have known that Monsanto’s glyphosate causes a number of birth malformations since at least 2002. Regulators misled the public about glyphosate’s safety, and in Germany the Federal Office for Consumer Protection and Food Safety told the European Commission that there was no evidence to suggest that glyphosate causes birth defects.

This study was published by Earth Open Sources, which is an organization that uses open source collaboration to advance sustainable food production. The report was headed by Dr M. Antoniou, Head Gene Expression and Therapy Group, from the Department of Medical and Molecular Genetics at King’s College London School of Medicine, UK. Dr. Antoniou was joined by 6 other doctors who have a similar biography. The report provides a comprehensive review of the peer-reviewed scientific literature documenting the serious health hazards posed by glyphosate and Roundup herbicide formulations. You can read the entire document here (http://earthopensource.org/files/pdfs/Roundup-and-birth-defects/RoundupandBirthDefectsv5.pdf).


“Our examination of the evidence leads us to the conclusion that the current approval of glyphosate and Roundup is deeply flawed and unreliable. In this report, we examine the industry studies and regulatory documents that led to the approval of glyphosate. We show that industry and regulators knew as long ago as the 1980s and 1990s that glyphosate causes malformation – but that this information was not made public. We demonstrate how EU regulators reasoned their way from clear evidence of glyphosate’s teratogenicity in industry’s own studies to a conclusion that minimized these findings in the EU Commission’s final review report”

Here (http://pubs.acs.org/doi/abs/10.1021/tx1001749) is another study that shows Glyphosate can cause abnormalities. It was published in 2010 by the American Chemical Society, the research was conducted at the University of Buenos Aires, Argentina.


“The direct effect of glyphosate on early mechanisms of morphogenesis in vertebrate embryos opens concerns about the clinical findings from human offspring in populations exposed to glyphosate in agricultural fields.”

Another study outlines how glyphosate toxicity leads to suppression of critical enzymes, and as a result links the Western diet to heart disease, Alzheimer, Parkinson, autism and more. (4) (http://www.mdpi.com/1099-4300/15/4/1416)

Glyphosate has also been linked to cancer, and various other health ailments. There are numerous studies documenting this and you can find our more information here (http://www.collective-evolution.com/?s=glyphosate+roundup).
It’s no secret that the brain of an embryo, fetus, or infant is at risk for significant and permanent damage from exposure to chemicals, like pesticides. Not long ago, a study published in the Journal Reproductive Toxicology successfully identified the presence of pesticides – associated with genetically modified foods in maternal, fetal and non-pregnant women’s blood. They also found the presence of Monsanto’s Bt toxin, and warn about toxin exposure during critical stages of development. (5) (https://www.uclm.es/Actividades/repositorio/pdf/doc_3721_4666.pdf)

The study concluded, apart from pesticides, that Monsanto’s Bt toxins are clearly detectable and appear to cross the placenta to the fetus. Some studies have linked Monsanto’s Bt toxin to cancer, damaging kidney cells, and more, especially when they are combined with Round-up

Multiple studies outline the need for further research when it comes to GMOs before we can say they are 100 % safe for consumption.


“Given the potential toxicity of these environmental pollutants and the fragility of the fetus, more studies are needed, particularly those using the placental transfer approach. Thus, our present results will provide baseline data for future studies exploring a new area of research relating to nutrition, toxicology and reproduction in women. Today, obstetric-gynecological disorders that are associated with environmental chemicals are not known. Thus, knowing the actual concentration of genetically modified foods in humans constitutes a cornerstone in the advancement of research in this area.” (5)

There is more research confirming that mothers who are exposed to commonly used, “safe” pesticides give birth to children with lower intelligence, structural brain abnormalities, behavioral disorders, compromised motor skills, higher rates of brain cancer and small head size. (6)(7)(8)(9)(10)(11)(12)(13)(14)(15)

In Late 2013, the European Food Safety Authority determined that pesticides, like neonicotinamides (linked to killing millions of bees, read more about that here (http://www.collective-evolution.com/?s=bees+pesticides)) may negatively affect the development of neurons and brain structures in unborn babies. (16) (http://www.efsa.europa.eu/en/press/news/131217.htm)

These are largely produced by Bayer pharmaceuticals.


“Given the ubiquitous exposure to many environmental toxicants, there needs to be renewed efforts to prevent harm. Such prevention should not await detailed evidence on individual hazards. Toxic exposure to chemical pollutants during these windows of increased susceptibility can cause disease and disability in childhood and across the entire span of human life.”(17) – Worlds foremost pediatricians, toxicologists, environmental scientists and epidemiologists at a conference held in 2007

Scientists at the conference (quote above) emphasized that common exposure to chemicals during critical stages of development of the fetus or newborns increases their chances of contracting diabetes, cancer, thyroid damage and more.


“Chemical pollution represents a serious threat to children, and to Man’s survival.” (18) (http://www.artac.info/fr/appel-de-paris/texte-en-six-langues/english_000082.html) – The Standing Committee of European Doctors.

Did you know that Americans alone are exposed to approximately 100,000 industrial chemicals? When it comes to babies, all pregnant woman are literally stuffed with hazardous chemicals. One study illustrated the tracking of just 163 chemicals, in which 99 percent of pregnant women tested positive for at least 43 different chemicals. (19)

There has even been significant concentrations of glyphosate found in the urine of people across Europe. You can read more about that here (http://www.collective-evolution.com/2013/09/04/significant-concentrations-of-glyphosate-aka-roundup-herbicide-found-in-urine-of-people-across-europe/). A new study from the U.S. Geological Survey, titled “Pesticides in Mississippi Air and Rain: A Comparison Between 1995 and 2007,” reveals that Roundup herbicide (aka glyphosate) and its toxic degradation byproduct AMPA were found in over 75% of the air and rain samples tested from Mississippi in 2007. You can read more about that here (http://www.collective-evolution.com/2014/03/04/roundup-herbicide-found-in-75-percent-of-air-rainfall-test-samples/).

The above makes it clear, toxins, especially when fetuses and newborns are exposed to them have the potential to be extremely harmful. So what else are they exposed to at a young age apart from environmental toxins? They are exposed to toxins commonly found in vaccinations.

Let’s be clear, more and more researchers are now considering the fact that toxins at critical stages of development can play a role in autism (as stated and illustrated many times in this article). The vaccine/autism debate has been a controversial one, but for pro-vaccine advocates, saying there is absolutely zero cause for concern is ridiculous. Just because something hasn’t been found, does not mean there is zero cause for concern. So lets look at both sides.

A study published in March of 2013 determined that “Increasing exposure to Antibody-Stimulating Proteins and Polysaccharides (antigens) in Vaccines is Not Associated with Risk of Autism.” You can view that study here. (http://jpeds.com/webfiles/images/journals/ympd/JPEDSDeStefano.pdf)

On the other hand, a study published in the peer-reviewed journal Translational Neurodegeneration provided epidemiological evidence supporting an association between increasing organic-Hg exposure from thimerosal-containing childhood and the risk of ASD diagnosis. You can take a look at that study here (http://www.ncbi.nlm.nih.gov/pubmed/24354891).

A paper published in the peer-reviewed International Journal of Environmental Research and Public Health titledThimerosal Exposure and the Role of Sulfation Chemistry and Thiol Availability in Autism (http://www.mdpi.com/1660-4601/10/8/3771) concluded:


“With the rate of children diagnosed with an ASD in the US now exceeding 1 in 50 children and the rate of children with neurodevelopment/behavioral disorders in the US now exceeding 1 in 6 children, and the preceding evidence showing that there is vulnerability to ™ that would not be known without extensive testing, the preponderance of the evidence indicates that ™ should be removed from all vaccines”

The list goes on and on, bottom line, vaccines are full of toxins, and they are administered at critical stages of development, which includes pregnant woman. This study (study linking autism to toxin exposure) further pushes the importance of looking at the multiple vaccines babies are bombarded with at birth, and the toxins found within them. For more CE articles on vaccines and autism, click HERE (http://www.collective-evolution.com/?s=vaccines+and+autism).

It also doesn’t help that vaccine manufactures and health authorities have known about and covered up (hidden from parents) dangers associated with vaccinations in order to protect herd immunity. Documents obtained by Lucija Tomljenovic, PhD, from the Neural Dynamics Research Group in the Department of Opthalmology and Visual Sciences at the University of British Columbia reveal that vaccine manufacturers, pharmaceutical companies and health authorities have known about multiple dangers associated with vaccines but chose to withhold them from the public. (20 (http://nsnbc.me/wp-content/uploads/2013/05/BSEM-2011.pdf))

At the end of the day, you always have a choice and you shouldn’t make that decision based on fear. Ridding your personal environment from harmful pesticides and toxins does contribute to a healthier environment. From personal experience, living in a virtually chemical free environment for a few years now, the difference felt when stepping into another is overwhelming. It’s amazing how desensitized we’ve become, and how we fail to notice these things on a daily basis.


Sources:
(1) http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1003518 (http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1003518)

(2)http://www.scientificamerican.com/article/autism-rise-driven-by-environment/ (http://www.scientificamerican.com/article/autism-rise-driven-by-environment/)

(3) http://www.nejm.org/doi/full/10.1056/NEJMoa1307491 (http://www.nejm.org/doi/full/10.1056/NEJMoa1307491)

(4) http://www.mdpi.com/1099-4300/15/4/1416 (http://www.mdpi.com/1099-4300/15/4/1416)

(5) https://www.uclm.es/Actividades/repositorio/pdf/doc_3721_4666.pdf (https://www.uclm.es/Actividades/repositorio/pdf/doc_3721_4666.pdf)

6.Rauh V, Arunajadai S, Horton M, Perera F, Hoepner L, Barr DB, et al. 2011. Seven-Year Neurodevelopmental Scores and Prenatal Exposure to Chlorpyrifos, a Common Agricultural Pesticide (http://dx.doi.org/10.1289/ehp.1003160). Environ Health Perspect 119:1196-1201.

7. Bouchard M, Chevrier J, Harley K, Kogut K, Vedar M, Calderon N, Trujillo C, Johnson C, Bradman A, Barr D, Eskenazi B. Prenatal Exposure to Organophosphate Pesticides and IQ in 7-Year Old Children. Environmental Health Perspectives, 2011; DOI: 10.1289/ehp.1003185

8. Engel S, et al. Prenatal Exposure to Organophosphates, Paraoxonase 1, and Cognitive Development in Childhood. Environmental Health Perspectives, 2011; DOI: 10.1289/ehp.1003183

9. Horton M, et al. Impact of Prenatal Exposure to Piperonyl Butoxide and Permethrin on 36-Month Neurodevelopment. Pediatrics 2011; 127:3 e699-e706; doi:10.1542/peds.2010-0133

10. Horton M, Kahn L, Perera F, Barr D, Rauh V. Does the home environment and the sex of the child modify the adverse effects of prenatal exposure to chlorpyrifos on child working memory? Neurotoxicology and Teratology, 2012; DOI: 10.1016/j.ntt.2012.07.004

11. Rauh V, et al. Brain anomalies in children exposed prenatally to a common organophosphate pesticide. PNAS 2012 109 (20) 7871-7876; published ahead of print April 30, 2012, doi:10.1073/pnas.1203396109

12.Oulhote Y, Bouchard M, Urinary Metabolites of Organophosphate and Pyrethroid Pesticides and Behavioral Problems in Canadian Children Environ Health Perspect; DOI:10.1289/ehp.1306667

13.. Ostrea EM, et al. 2011. Fetal exposure to propoxur and abnormal child neurodevelopment at two years of age (http://dx.doi.org/10.1016/j.neuro.2011.11.006). Neurotoxicology.

14. Greenop K, Peters S, Bailey H, et al. Exposure to pesticides and the risk of childhood brain tumors. Cancer Causes & Control. April 2013

15. Kimura-Kuroda J, Komuta Y, Kuroda Y, Hayashi M, Kawano H (2012) Nicotine-Like Effects of the Neonicotinoid Insecticides Acetamiprid and Imidacloprid on Cerebellar Neurons from Neonatal Rats. PLoS ONE 7(2): e32432. doi:10.1371/journal.pone.003243

(16) http://www.efsa.europa.eu/en/press/news/131217.htm (http://www.efsa.europa.eu/en/press/news/131217.htm)

(17) http://articles.latimes.com/2007/may/25/nation/na-fetuses25 (http://articles.latimes.com/2007/may/25/nation/na-fetuses25)

(18) http://www.artac.info/fr/appel-de-paris/texte-en-six-langues/english_000082.html (http://www.artac.info/fr/appel-de-paris/texte-en-six-langues/english_000082.html)

(19) Tracey J. Woodruff, Ami R. Zota, Jackie M. Schwartz. Environmental Chemicals in Pregnant Women in the US: NHANES 2003-2004. Environmental Health Perspectives, 2011; DOI: 10.1289/ehp.1002727
http://www.truth-out.org/news/item/23267-autism-nation-americas-chemical-brain-drain

(20) http://nsnbc.me/wp-content/uploads/2013/05/BSEM-2011.pdf (http://nsnbc.me/wp-content/uploads/2013/05/BSEM-2011.pdf)

Hervé
1st June 2014, 13:00
The Many Benefits of Hydrogen Peroxide (http://educate-yourself.org/cancer/benefitsofhydrogenperozide17jul03.shtml)


Father Richard Willhelm
We are just beginning to learn exactly how H202 works. It was reported to work as far back as 1920. The English medical journal, Lancet, then reported that intravenous infusion was used successfully to treat pneumonia in the epidemic following World War I. In the 1940's Father Richard Willhelm, the pioneer in promoting peroxide use, reported on the compound being used extensively to treat everything from bacterial-related mental illness to skin disease and polio. Father Willhelm is the founder of "Educational Concern for Hydrogen Peroxide" (ECHO, a nonprofit organization dedicated to educating the public on the safe use and therapeutic benefits of hydrogen peroxide.) Much of the interest in hydrogen peroxide waned in the 1940's when prescription medications came on the scene. Since that time there has been little economic interest in funding peroxide research. After all, it is dirt cheap and non-patentable. Even still, in the last 25 years, over 7,700 articles relating to hydrogen peroxide have been written in the standard medical journals. Thousands more, involving its therapeutic use, have appeared in alternative health publications. The number of conditions helped by hydrogen peroxide is astounding. The reported dangers and side effects are few and often conflicting.

Lifebringer
1st June 2014, 13:54
Just awful what these corporate pharma lab monsters in charge, will do the children and people to make a buck. This research belongs in the People's hands, not some military or corporate psychotic boardroom. To think whenever they want to bypass safety and regulation, they buy a puppet that walks and talks like the people. Then they pay the puppet to push their bills or deregulatory oversight, and roll the dice, until people start showing symptoms, "only" they know about in some safe from their scientist, with a copy to the lawyer on what else can be linked to point the other way. Think fluoride ingestion, nano invasion, backyard auto mechanic medicine, that fixes one thing, and destroys the rest.

WE need honest to God decent doctors driven by opportunity and oath, and not profit margin CEO's on the pharma dole as a mole in a company.

Time for some sad truths about being fool hearty enough to believe anything with profit as a motive, without checking and double checking to verify safety of products. Follow the money trail and read the comments of actual people who've used the medicine while searching for answers on the net. Most people will warn other people and tell what the company is doing to resolve problems w/products/medicine.

Hervé
5th June 2014, 13:40
What We Didn't Know About the Brain That Changes Everything
(http://www.greenmedinfo.com/blog/what-we-didnt-know-about-brain-changes-everything)
Posted on: Monday, June 2nd 2014 at 2:45 pm
Written By: Dr. Kelly Brogan, M.D. (http://www.greenmedinfo.com/gmi-blogs/drbrogan@kellybroganmd.com)



http://cdn.greenmedinfo.com/sites/default/files/ckeditor/Sayer%20Ji/images/brain_neuroimmunology_mysteries.jpg

Sometimes science gets things wrong. With acknowledgement of these fundamental misapprehensions, whole swaths of dogma have to be unraveled, deconstructed, and rebuilt. The sooner the better.

Ten years ago, science assumed that immunity was in the body, not the brain, which was thought to have "immune privilege". What does it mean to learn that the brain has an immune system? Does this change our understanding of mental illness? Neurology? Cancer? What about risks of side effects to pharmaceutical interventions that target the immune system such as vaccines?

A seminal paper entitled, Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059681/), helps to elucidate the history of this paradigm shift. Scientific dogma had it that the immune system might infiltrate a brain in acute trauma or pathology. The earliest observations of the role of the immune system in even healthy brains arose from observations of cognitive impairment in severe combined immunodeficient mice who had peripheral T-cell depletion (but no specific blood-brain-barrier breach).

With the activity of agents called cytokines, complement, and complexes that help to identify invasive pathogens such as MHC, the presence alone, of these agents represents a new way of thinking about brain function. Then there is the consideration that patterns of immune functioning change over the course of neurodevelopment with immune agents participating in learning and brain growth. Sprinkle in the daunting complexity of genetic individuality as demonstrated in this quote:
"One of the defining features of MHC molecules and their receptors is their complexity. They are both polygenic-containing multiple genes and polymorphic-containing multiple variants of each gene. The MHC genes are the most polymorphic genes known."
...and we end up with more questions than we have answers.
Suffice it to say:
"The link between environmental factors, the immune response, and neurological dysfunction is not completely clear at present, but it is receiving increasing attention and support...the sheer number of immune molecules that could be important for nervous system develop­ment and function is staggering. Although much progress has been made in the past 10 years in our appreciation that immune molecules play critical roles in the healthy brain, the large major­ity of immune molecules have not yet been studied for their presence and function in the brain. For the immune molecules that we know are important, almost nothing is understood about their mechanisms of action."
The complexity of this review serves to highlight just how much we have left to discover about immune activity in the brain relative to the rest of the body. That said, the notion of immune-brain cross-talk has become the underpinning of modern theories of cytokine models of mental illness.

When the brain's immunity goes awry - Depression
One of the most predictable side effects of interferon therapy for Hepatitis C is depression. In fact, 45% of patients develop depression (https://www.ncbi.nlm.nih.gov/m/pubmed/22142332/?i=5&from=/19926405/related) with interferon treatment, which appears to be related to elevated levels of inflammatory cytokines IL-6 and TNF. Cytokines can also be induced by lipopolysaccharide (LPS), an endotoxin produced by gram-negative bacteria that can be administered orally and is employed in animal models to induce depression-like syndromes. Mice that lack IL1-B (http://www.jneuroinflammation.com/content/10/1/54) (a cytokine that mediates inflammatory response), however, are protected against these LPS-mediated "depressive symptoms" (i.e., lost interest in sugar water), suggesting that these inflammatory messengers may be a key part of the depression equation.

Cytokines such as IL-1, IL-6, and TNF-alpha are the messengers of distress and have all been shown to be elevated in the setting of depression, and in a linear (http://www.sciencedirect.com/science/article/pii/S0306453014001152) and predictive (http://www.ncbi.nlm.nih.gov/pubmed/21037214) relationship. These cytokines can traverse the blood brain barrier and may also stimulate afferent neurons such as the vagus (http://www.usc.edu/projects/nexus/faculty/dept-ldsg/finchcaleb/388%20Finch%20Cytokines%20and%20Cognition.pdf) nerve.

Once in the brain, immune hubs called microglia are activated where an enzyme called IDO (indoleamine 2 3-dioxygenase) has been shown (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140295/) to direct tryptophan away from the production of serotonin and melatonin and towards the production of an NMDA agonist (http://en.wikipedia.org/wiki/NMDA_receptor) called quinolinic acid.

In the context of inflammation, however, cortisol, prolactin, and sex hormones are often dysregulated; in this model, depression is thought to represent a high cortisol state which may result from elevated levels of inflammatory cytokines. This may, in part, explain the efficacy of exercise (http://summaries.cochrane.org/CD004366/exercise-for-depression) in the treatment of depression and yoga (http://www.ncbi.nlm.nih.gov/pubmed/24788589), and meditation (http://kellybroganmd.com/article/meditation-evidence-based-psychiatric-treatment-mercola/) in downregulation of inflammation.


How do we modulate immunity?
The most powerful and controllable access point to the immune system is the gut. With 70% of it housed in the Gut Associated Lymphoid Tissue (GALT) in the intestinal wall, the ecosystem of microbial residents are responsible for influencing the immune gatekeepers such as dendritic cells. These microbes include primarily around 100 trillion bacteria that outnumber our human cells 10:1, archaea, parasites, and viruses including bacteriophages. These microbes transfer genetic information between each other and to the human host, and also carry out a number of activities such as production of fatty acids (http://www.greenmedinfo.com/blog/Impact%2520of%2520Administered%2520Bifidobacterium%2520on%2520Murine%2520Host%2520Fatty%2520Acid%252 0Composition), neurotransmitters (http://www.ncbi.nlm.nih.gov/pubmed/22612585), B vitamins (http://www.greenmedinfo.com/blog/Antioxidative%2520potential%2520of%2520folate%2520producing%2520probiotic%2520Lactobacillus%2520helv eticus%2520CD6), digesting gluten (http://kellybroganmd.com/article/gluten-amd-gut-bugs/), and even detoxification of environmental chemicals (http://www.ncbi.nlm.nih.gov/pubmed/22497505).

While the microbiome is readily influenced by diet, it is the maternal gift (http://kellybroganmd.com/article/guts-bugs-and-babies/) that keeps on giving – influenced by the mother's gut flora during pregnancy (http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1001631), birth mode, breastfeeding, and finally weaning diet (http://www.sciencedirect.com/science/article/pii/S0022347614001401).

What's wrong with this picture?
Given the vast interconnectedness we have just explored, perhaps breaching the blood brain barrier with fat-loving metals injected into the blood stream (http://www.greenmedinfo.com/blog/can-we-continue-justify-injecting-aluminum-children) with a variety of pathogens and chemical additives may require reevaluation. Vaccines may be the most egregious example of head-in-the-sand "science" that has failed to incorporate modern theories of intersystem immunology – gut, endocrine, adrenal – as well as the vast personalization required for such an intervention based on genetics and preexisting environmental exposures.

Aluminum, used as a vaccine adjuvant (http://www.greenmedinfo.com/toxic-ingredient/vaccine-adjuvants), is administered to a child sixteen times before the age of two (http://www.vaccinationcouncil.org/2014/05/25/the-great-divide-spanning-the-chasm-between-truth-and-egregious-lies-by-shawn-siegel/). It activates microglia in the brain and is strongly linked to Alzheimers, Parkinson's disease and autoimmune disorders (http://www.ncbi.nlm.nih.gov/pubmed/11130287). This is a known neurotoxin and potent immune stimulant – added because the newborn immune system is actually built not to respond. This has been referred to as the anti-inflammatory phenotype and speaks to the powerful interplay between an infant, their mother's milk, and the priming of their immune system in the first 2 years of life. Several exploratory analysis have argued for a causative role for aluminum in autism incidence including one by Lucija Tomeljenovic and Shaw (http://www.ncbi.nlm.nih.gov/pubmed/22099159) and by MIT researcher, Stephanie Seneff (http://www.mdpi.com/1099-4300/14/11/2227).

For instance, one study (http://www.neurology.org/cgi/content/abstract/72/10/873) found that children who received the Engerix B Hepatitis B vaccine were 74% more likely to develop "central nervous system inflammatory demyelination" than children who did not receive the vaccine, and 177% more likely to develop multiple sclerosis.

The only primate study (http://www.ncbi.nlm.nih.gov/pubmed/20711932) done with an unvaccinated control group, concerningly demonstrated delayed acquisition of neurodevelopmental reflexes in the thimerosol (ethylmercury-forming preservative) Hep B vaccinated group (particularly in those with low birth weight and gestational age) relative to the unexposed group. Studies such as this, along with those like this (http://www.greenmedinfo.com/blog/Hepatitis%2520B%2520triple%2520series%2520vaccine%2520and%2520developmental%2520disability) that determined a 9x greater risk for receipt of special educational services in boys receiving the pre-2001 Hep B vaccine series, and one that suggested a 3-fold greater risk of autism (http://www.ncbi.nlm.nih.gov/pubmed/21058170) diagnosis likely led to the removal of thimerosol from the product in 2001.

The thimerosol-containing vaccine (http://www.greenmedinfo.com/toxic-ingredient/thimerosal) was on the market for 19 years before this change (and it is still an ingredient of the flu vaccine and tetanus), which may raise concerns for some about the delay in remediating dangers (http://jrs.sagepub.com/content/104/12/510) associated with these products. These dangers are learned of post-hoc, in the field, after many children have paid the price of inadequate placebo-controlled, long-term study.

It seems that, by design, vaccines may be a means of sending the immune system, and therefore the brain, a signal of harm (http://kellybroganmd.com/article/current-theories-of-immunity/).

Real Medicine
Understanding these interrelationships in the beginning of a new form of medicine: one that regards the body and mind as a whole, that appreciates that myriad environmental and lifestyle influences upon genetic expression, and that seeks to promote optimal functioning rather than suppress symptoms, co-opt functioning, and kill pathogens. Millions of years of evolution (http://www.greenmedinfo.com/blog/why-vaccines-arent-paleo) have brought us to this place and we are just beginning to look through the keyhole.

Tesla_WTC_Solution
7th June 2014, 19:53
Thanks a million you guys for helping with this thread.
Been sick/freaked out/going through some life changes recently!

Thanks to those of you sending good vibes/prayers,
and to those who sent me messages!

:)

Thanks again to all those who helped this thread either by asking questions or posting content -- help needed/appreciated!

You DO make a difference ....

Tesla_WTC_Solution
14th June 2014, 06:28
this was linked to CNN:

http://www.hcplive.com/articles/Combo-Vaccine-Raises-Risk-of-Fever-related-Seizures?sao=385&utm_source=outBrain&utm_medium=HCPLive&utm_campaign=Epilepsy

Combo Vaccine Raises Risk of Fever-related Seizures
| June 11, 2014

TUESDAY, June 10, 2014 (HealthDay News) -- One-year-olds who receive Priorix-Tetra -- the measles-mumps-rubella-varicella (MMRV) vaccine used in Canada -- are twice as likely to develop a fever-related seizure as children who receive separate MMR and varicella vaccines, according to research published online June 9 in CMAJ, the journal of the Canadian Medical Association. The findings are in line with a 2010 study of the MMRV vaccine used in the United States, known as ProQuad.

Shannon MacDonald, PhD, RN, of the University of Calgary in Alberta, Canada, led the new study. The findings are based on records for almost 278,000 Alberta children between the ages of 12 and 23 months. The children received either the MMRV or separate MMR and varicella vaccines on the same day.

The researchers found that children's seizure rate peaked seven to 10 days after they were vaccinated. At that point, there were almost six seizures for every 10,000 doses of the MMRV, versus two seizures for every 10,000 doses of the separate vaccines.

The authors note that, based on the ProQuad study, the US Advisory Committee on Immunization Practices changed its stance on the MMRV. Now it says that unless parents ask about the combined vaccine, doctors should default to separate shots for young children getting their first dose of the MMR and varicella vaccines. In general, fever-related seizure is uncommon at ages 4 to 6 years, the age at which second dose is typically given, and the advisory committee says the MMRV is the better option for the second dose.

Full Article
Abstract
Full Text

http://www.healthday.com/wwwroot/intellisphere/newsfeed_daily_pb_t.dat http://dynamis.hcplive.com/login Copyright © 2014 HealthDay. All rights reserved. - See more at: http://www.hcplive.com/articles/Combo-Vaccine-Raises-Risk-of-Fever-related-Seizures?sao=385&utm_source=outBrain&utm_medium=HCPLive&utm_campaign=Epilepsy#sthash.GSsdvhtH.dpuf

Hervé
15th June 2014, 17:24
The Lancet: Fluoride IS a Neurotoxin! (http://www.activistpost.com/2014/06/the-lancet-fluoride-is-neurotoxin.html)

Catherine J. Frompovich
Activist Post (http://www.activistpost.com/2014/06/the-lancet-fluoride-is-neurotoxin.html)

Who would have thought that it ever would have happened? Someone in mainstream medicine and peer reviewed literature and journals would publish the ‘unthinkable’: fluoride, the stuff they put into municipal water supplies supposedly to ‘protect’ teeth from cavities, is a neurotoxin. Wow! And congratulations to doctors Philippe Grandjean, MD, and Philip J Landrigan, MD, two researchers who published their findings in The Lancet Neurology, Volume 13, Issue 3, Pages 330 to 338, March 2014. [1]

In the Summary published for their article, it states that
Neurodevelopmental disabilities, including autism, attention-deficit hyperactivity disorder, dyslexia, and other cognitive impairments, affect millions of children worldwide, and some diagnoses seem to be increasing in frequency. [CJF emphasis added] Probably nothing more can confirm that as scientific, demographic, and the horrible truth! And, everyone—not just children—are paying the consequences for all chemical exposures. Now let’s see if Drs. Granjean and Landrigan will have the scientific integrity to expose neurotoxins in vaccines for what they truly are. I’d like to give them a reference where to start looking for ideas: My 2013 book Vaccination Voodoo, What YOU Don’t Know About Vaccines (http://www.amazon.com/Vaccination-Voodoo-What-About-Vaccines/dp/1484923820/ref=as_li_tf_sw?&linkCode=wsw&tag=permacultucom-20), available on Amazon.com.

In that book I also mention fluoride. Why? Because what is not documented by peer reviewed ‘science’ journals is the chemical interaction(s) between fluoride and vaccine neurotoxins and other vaccine chemicals. Add to that list, the chemicals we are forced to eat in our food, especially glyphosate from inordinate spraying of genetically modified crops such as corn, sugar beets, soy, canola, alfalfa animal feed, and possibly squash and potatoes.

Add to that all the herbicides, fungicides, pesticides, etc. that are sprayed on fruits, vegetables, and animal feeds that get into the food chain BIG time. For more information about those “…cides,” which are intended to kill life forms, readers and both doctors may want to read my 2010 book Our Chemical Lives And The Hijacking Of Our DNA, A Probe Into What’s Probably Making Us Sick (http://www.amazon.com/Our-Chemical-Lives-And-Hijacking/dp/1439255369/ref=as_li_tf_sw?&linkCode=wsw&tag=permacultucom-20), also available on Amazon.com.

Any chemical whose purpose is to kill a life form must be considered as a neurotoxin, endocrine disruptor, or carcinogen – at a minimum – in my opinion as a consumer health researcher for almost 37 years.

Not to digress from the importance of this article about fluoride, but the USA can put a nation back to work by cleaning up the environment from toxicity once the chemical and pharmaceutical industries are exposed for what they truly are: Biohazards!

Here’s a short YouTube regarding fluoridation of water in other countries.


SBnu76__LZE

According to the British Fluoridation Society as of November 2012 [2], the following countries fluoridate portions of their population:


http://3.bp.blogspot.com/-OUvttJn2uZA/U5uBWKN47eI/AAAAAAAAc_M/WEcsIx-sGpU/s1600/country_list.png (http://3.bp.blogspot.com/-OUvttJn2uZA/U5uBWKN47eI/AAAAAAAAc_M/WEcsIx-sGpU/s1600/country_list.png)

So, what has the addition of fluoride to municipal water supplies done for human health? Not very much, except cause health problems [3], including:


A Harvard study shows that fluoride lowers IQ in children. [4] [6]
Crippling bone disease, i.e., skeletal fluorosis [5]
Severe dental fluorosis, instead of protecting teeth. If you don’t know what that looks like, here’s a file showing dental fluorosis (https://www.google.com/search?q=severe+dental+fluorosis&tbm=isch&tbo=u&source=univ&sa=X&ei=31KbU4CnMfbNsQTy1YCQAQ&sqi=2&ved=0CBwQsAQ&biw=993&bih=550).

One would think with the publication in 2010 that kid’s IQs are adversely and negatively impacted, federal, state and city governments would have stopped municipal water fluoridation immediately. No! they have not, and it’s now 2014. Does that mean that water fluoridation has a purpose which is not being acknowledged? Could it be the deliberate dumbing-down of the U.S. population? Or, could it be to make more business for dentists, doctors, and the pharmaceutical industry? What do you think?


Notes:
[1] http://www.thelancet.com/journals/laneur/article/PIIS1474-4422(13)70278-3/fulltext#article_upsell (http://www.thelancet.com/journals/laneur/article/PIIS1474-4422%2813%2970278-3/fulltext#article_upsell)

[2] http://fluoridealert.org/content/bfs-2012/

[3] http://fluoridealert.org/issues/health/

[4] http://articles.mercola.com/sites/articles/archive/2012/08/07/effects-of-fluoride-to-children.aspx

[5] http://en.wikipedia.org/wiki/Skeletal_fluorosis

[6] http://ehp.niehs.nih.gov/wp-content/uploads/2012/09/ehp.1104912.pdf


Resource:
Dr. Rima Truth Reports / Fluoride Facts and Myths
http://drrimatruthreports.com/fluoride-facts-and-myths/

Catherine J Frompovich (website (http://www.catherinejfrompovich.com/)) is a retired natural nutritionist who earned advanced degrees in Nutrition and Holistic Health Sciences, Certification in Orthomolecular Theory and Practice plus Paralegal Studies. Her work has been published in national and airline magazines since the early 1980s. Catherine authored numerous books on health issues along with co-authoring papers and monographs with physicians, nurses, and holistic healthcare professionals. She has been a consumer healthcare researcher 35 years and counting.

Tesla_WTC_Solution
15th June 2014, 17:34
THANK you.

Btw anyone here familiar with the concept of "silent seizures"?

one of the big mysteries of ASD/bipolar

there are seizures so small they are difficult to notice without an EEG or some such device.

and ASD people all over the world have these.

Hervé
15th June 2014, 17:47
Interesting propaganda... so, read between 'em lines :)


Vaccine combo doubles seizure risk in babies (http://www.vancouversun.com/health/family-child/Vaccine%20combo%20doubles%20seizure%20risk%20babies/9923344/story.html)

However, threat remains relatively small: study says

By Elizabeth Payne and Jeff Lee, Postmedia news and Vancouver Sun June 10, 2014


http://www.vancouversun.com/health/family-child/cms/binary/9923346.jpg

MIAMI, FL - JUNE 02: India Ampah holds her son, Keon Lockhart, 12 months old, as pediatrician Amanda Porro M.D. administers a measles vaccination during a visit to the Miami Children’s Hospital on June 2, 2014 in Miami, Florida. The Centers for Disease Control and Prevention last week announced that in the United States they are seeing the most measles cases in 20 years as they warned clinicians, parents and others to watch for and get vaccinated against the potentially deadly virus.
Photograph by: Joe Raedle, Getty Images

OTTAWA — Combining two common childhood vaccines into one — rather than administering them separately — doubles the risk of febrile seizures in children, a study published in the Canadian Medical Association Journal has found.

Febrile seizures, convulsions brought on by fever in infants or young children, are a rare side-effect of measles-mumps-rubella vaccine, occurring at a rate of less than two seizures per 10,000 doses. When the MMR vaccine is combined with the vaccine against chickenpox, creating the MMRV (for varicella) vaccine, that risk doubles. It still remains relatively small, however — at a rate of 3.52 seizures per 10,000 doses, according to the study by a team led by Dr. Shannon MacDonald at the University of Calgary’s faculty of medicine. Seizures among high-risk children were not significantly different, the study also found.

In British Columbia, the doubled MMRV vaccine is not given to babies because of the higher risk of febrile seizures, according to Dr. Monika Naus, the medical director of immunization programs for the B.C. Centre for Disease Control.

In July B.C. will begin administering the MMRV as a second dose to school-aged children who have already had separate vaccines against measles-mumps-rubella and chickenpox. But those children are at no risk because febrile seizures are a factor only in babies, Naus said.

Febrile seizures rarely have long-term effects, MacDonald said, but they do cause distress “and may undermine confidence in immunization programs.”

And that is a big worry.

At a time when measles, which had been eradicated in North America, is seeing a record resurgence, anything with the potential to reduce vaccination rates further is studied carefully by public health officials. A growing anti-vaccine movement has led to pockets of lower vaccination rates across North America.

In fact, the combined measles-mumps-rubella-varicella vaccine was adopted in some regions — although not in Ontario for the first dose children receive — to address waning vaccine rates.

There are good reasons to use the combined vaccine, MacDonald said.

“Combining MMR and varicella into a single vaccine decreases pain for children and distress for parents, thus addressing common barriers to vaccine uptake and may improve vaccination coverage levels and decrease immunization delivery costs.”

Deciding whether to offer separate vaccines or a combination is, ultimately, a policy decision, said MacDonald, whose findings were consistent with a study on the U.S. version of the vaccine.

The U.S. findings led its Advisory Committee on Immunization Practices to withdraw its preference for use of the combination vaccine for the first dose (usually administered to children at about 12 months). The committee advised health officials and parents to discuss the benefits and risks of each option before choosing. If there is no preference, it recommends the separate vaccines be given for the first dose in young children (12-47 months) and the combined vaccine be given to older children or those getting a second dose.

Naus said when the U.S. findings came out the BCCDC chose to not institute a combined vaccine for babies. But it decided in 2012 to administer the combination to children ages 4-6 at the beginning of school starting in 2014.

The findings come as B.C. suffers through a resurgence of measles, particularly in the upper Fraser Valley because of parental resistance to vaccinations.

But Naus said people need to understand their children are more at risk of illness and possibly death from not getting vaccinated.

Parents also need to understand febrile seizures are not dangerous in the long term and children usually outgrow them by the age of two, she said.

“We know that vaccines can cause febrile seizures. Febrile seizures are benign. Children who have febrile seizures with vaccines will have febrile seizures after other triggers like infections, and the important thing is vaccinations prevent those infections so these children are actually better off immunized than getting the real measles, the real chicken pox, which are associated with far greater levels of fever and illness,” Naus said.

The researchers studied data from 277,774 children between 12 and 23 months who received either the combined MMRV vaccine or separate MMR and varicella vaccines. Alberta, where the study was conducted, replaced the separate vaccines with the combined vaccine in 2010. Nine of 13 Canadian provinces and territories administer the combined vaccine as part of their routine childhood immunization schedule. In Ontario, children are given separate vaccines for the first dose and the combined vaccine when they are between four and six years old.

A spokesperson for the Ontario Ministry of Health said it will review the study but that it already recommends separate vaccines for younger ages because of previous studies with similar findings.

© Copyright (c) The Vancouver Sun

Tesla_WTC_Solution
15th June 2014, 18:20
That's correct, the MSM focuses on the absolute, i.e. the visible result -- they totally ignore the "degrees of damage" done by the practice of injecting foreign substances into babies.

MSM needs to be knocked out because it's a stupefying force. It removes nuance.

Tesla_WTC_Solution
16th June 2014, 18:07
In The Stand (1990 version), Stephen King mentions very briefly the interaction between acetylcholine and cholinesterase -- the former sensitizes the nerves for better transmission, according to King, and the latter destroys the former when the signal has been transmitted.

He says this chemical process is very important in terms of being able to "stop", or to "feel right".

My son does a lot of self-aggravation, like rocking and biting his own skin.
He also likes to masturbate when he is upset (he's only 6 though).
I've gotten negative feedback from the woman supervising my visits (she has worked with us for less than a month),
and this is a behavior my son has engaged in since he started living there (close to two years now).

Personally I don't think any child should be punished for masturbating, do you guys?
But I did explain the social aspects of autism to this woman, because she seems unaware of how serious it can be.

She actually made a rather ignorant comment about my boy, that "they used to put them in asylums" --
but that was way before the autism rate exploded like it has recently. She is out of line saying that, too.

My son's sexuality isn't my business and it certainly isn't hers.
Anyhow I was wondering if when these kids get upset, they overproduce acetylcholine and not enough cholinesterase.


http://www.ncbi.nlm.nih.gov/pubmed/20190638

Clin Neuropharmacol. 2010 May;33(3):114-20. doi: 10.1097/WNF.0b013e3181d6f7ad.
Cholinergic abnormalities in autism: is there a rationale for selective nicotinic agonist interventions?
Deutsch SI1, Urbano MR, Neumann SA, Burket JA, Katz E.
Author information
Abstract
The core dysfunctions of autism spectrum disorders, which include autistic disorder, Asperger disorder, and pervasive developmental disorder not otherwise specified, include deficits in socialization and communication and a need for the preservation of "sameness;" intellectual impairment and epilepsy are common comorbidities. Data suggest that pathological involvement of cholinergic nuclei and altered expression of acetylcholine receptors, particularly nicotinic acetylcholine receptors, occur in brain of persons with autistic disorder. However, many of these studies involved postmortem tissue from small samples of primarily adult persons. Thus, the findings may reflect compensatory changes and may relate more closely to intellectual impairment and the confounding effects of seizures and medications, as opposed to the core dysfunctions of autism. Nonetheless, because of the roles played by acetylcholine receptors in general, and nicotinic acetylcholine receptors in particular, in normal processes of attention, cognition, and memory, selective cholinergic interventions should be explored for possible therapeutic effects. Additionally, there are electrophysiological data that complement the clinical observations of frequent comorbid seizure disorders in these patients, suggesting a disturbance in the balance of excitatory and inhibitory tone in the brains of persons with autistic disorders. Conceivably, because the alpha7 nicotinic acetylcholine receptor is located on the surface of gamma-aminobutyric acid inhibitory neurons, selective stimulation of this receptor would promote gamma-aminobutyric acid's release and restore diminished inhibitory tone. The development of agonists and partial agonists for nicotinic acetylcholine receptors and positive allosteric modulators that enhance the efficiency of coupling between the binding of agonist and channel opening should facilitate consideration of clinical trials.


PMID: 20190638 [PubMed - indexed for MEDLINE]
Publication Types, MeSH Terms, Substances
LinkOut - more resources

_________________________________________

http://www.nature.com/npp/journal/v39/n4/full/npp2013274a.html

Original Article

Neuropsychopharmacology (7 October 2013) | doi:10.1038/npp.2013.274

ARTICLE TOOLS
SEARCH PUBMED FOR
Golan Karvat
Tali Kimchi
Acetylcholine Elevation Relieves Cognitive Rigidity and Social Deficiency in a Mouse Model of Autism

Golan Karvat and Tali Kimchi

Abstract
Autism spectrum disorders (ASD) are defined by behavioral deficits in social interaction and communication, repetitive stereotyped behaviors, and restricted interests/cognitive rigidity. Recent studies in humans and animal-models suggest that dysfunction of the cholinergic system may underlie autism-related behavioral symptoms. Here we tested the hypothesis that augmentation of acetylcholine (ACh) in the synaptic cleft by inhibiting acetylcholinesterase may ameliorate autistic phenotypes. We first administered the acetylcholinesterase inhibitor (AChEI) Donepezil systemically by intraperitoneal (i.p.) injections. Second, the drug was injected directly into the rodent homolog of the caudate nucleus, the dorsomedial striatum (DMS), of the inbred mouse strain BTBR T+tf/J (BTBR), a commonly-used model presenting all core autism-related phenotypes and expressing low brain ACh levels. We found that i.p. injection of AChEI to BTBR mice significantly relieved autism-relevant phenotypes, including decreasing cognitive rigidity, improving social preference, and enhancing social interaction, in a dose-dependent manner. Microinjection of the drug directly into the DMS, but not into the ventromedial striatum, led to significant amelioration of the cognitive-rigidity and social-deficiency phenotypes. Taken together, these findings provide evidence of the key role of the cholinergic system and the DMS in the etiology of ASD, and suggest that elevated cognitive flexibility may result in enhanced social attention. The potential therapeutic effect of AChEIs in ASD patients is discussed.

To read this article in full you may need to log in, make a payment or gain access through a site license (see right).



guys girls and lurkers, this is a big one, please read up on Acetylcholine and autism!

p.s. actually looks like the 2nd paper says elevating the acetylcholine helps them.
so maybe they have too much cholinesterase. :pray:

Tesla_WTC_Solution
16th June 2014, 18:44
Memory, Mtor pathway, Cholinergic system

Please bear with me, I don't have the words to explain this one:

But these concepts actually do relate to each other, check out the following:

http://www.ncbi.nlm.nih.gov/pubmed/24076274

Neurobiol Learn Mem. 2013 Nov;106:246-57. doi: 10.1016/j.nlm.2013.09.013. Epub 2013 Sep 27.
Hippocampal long term memory: effect of the cholinergic system on local protein synthesis.
Lana D1, Cerbai F, Di Russo J, Boscaro F, Giannetti A, Petkova-Kirova P, Pugliese AM, Giovannini MG.
Author information
Abstract
The present study was aimed at establishing a link between the cholinergic system and the pathway of mTOR and its downstream effector p70S6K, likely actors in long term memory encoding. We performed in vivo behavioral experiments using the step down inhibitory avoidance test (IA) in adult Wistar rats to evaluate memory formation under different conditions, and immunohistochemistry on hippocampal slices to evaluate the level and the time-course of mTOR and p70S6K activation. We also examined the effect of RAPA, inhibitor of mTORC1 formation, and of the acetylcholine (ACh) muscarinic receptor antagonist scopolamine (SCOP) or ACh nicotinic receptor antagonist mecamylamine (MECA) on short and long term memory formation and on the functionality of the mTOR pathway. Acquisition test was performed 30 min after i.c.v. injection of RAPA, a time sufficient for the drug to diffuse to CA1 pyramidal neurons, as demonstrated by MALDI-TOF-TOF imaging. Recall test was performed 1 h, 4 h or 24 h after acquisition. To confirm our results we performed in vitro experiments on live hippocampal slices: we evaluated whether stimulation of the cholinergic system with the cholinergic receptor agonist carbachol (CCh) activated the mTOR pathway and whether the administration of the above-mentioned antagonists together with CCh could revert this activation. We found that (1) mTOR and p70S6K activation in the hippocampus were involved in long term memory formation; (2) RAPA administration caused inhibition of mTOR activation at 1 h and 4 h and of p70S6K activation at 4 h, and long term memory impairment at 24 h after acquisition; (3) scopolamine treatment caused short but not long term memory impairment with an early increase of mTOR/p70S6K activation at 1 h followed by stabilization at longer times; (4) mecamylamine plus scopolamine treatment caused short term memory impairment at 1 h and 4 h and reduced the scopolamine-induced increase of mTOR/p70S6K activation at 1 h and 4 h; (5) mecamylamine plus scopolamine treatment did not impair long term memory formation; (6) in vitro treatment with carbachol activated mTOR and p70S6K and this effect was blocked by scopolamine and mecamylamine. Taken together our data reinforce the idea that distinct molecular mechanisms are at the basis of the two different forms of memory and are in accordance with data presented by other groups that there exist molecular mechanisms that underlie short term memory, others that underlie long term memories, but some mechanisms are involved in both.
Copyright © 2013 Elsevier Inc. All rights reserved.
KEYWORDS:
ACQ; ACh; Acetylcholine; CCh; IA; Inhibitory avoidance; Long term memory; M; MALDI-TOF-TOF; MECA; Mecamylamine; RAPA; REC; Rapamycin; SCOP; SEM; Scopolamine; aCSF; acetylcholine; acquisition; artificial cerebrospinal fluid; carbachol; mAChR; mTOR; mTORC1; mammalian target of rapamycin; mammalian target of rapamycin complex 1; matrix assited laser desorption ionization-time of flight-time of flight; mean; mecamylamine; muscarinic acetylcholine receptors; nAChR; nicotinic acetylcholine receptors; p70S6K; p70S6Kinase; rapamycin; recall; scopolamine; standard error of the mean; step-down inhibitory avoidance
PMID: 24076274 [PubMed - in process]
Publication Types





Really wishing some scientist out there would help us.

Hervé
24th June 2014, 13:20
Autism, developmental delays linked to pesticide exposure during pregnancy - study

Published time: June 24, 2014 00:24
Get short URL (http://rt.com/usa/167976-autism-gestational-pesticide-exposure/)


http://cdn.rt.com/files/news/29/02/80/00/autism-gestational-pesticide-exposure.si.jpg
Reuters/Doug Wilson/USDA


Exposure to several common agricultural pesticides during pregnancy increases the risk of developmental delays and autism in children by two-thirds, a new study found. While researchers did not say pesticides cause autism, a direct link is plausible.

Researchers at the University of California, Davis’ MIND Institute tracked associations with specific classes of pesticides (including organophosphates, pyrethroids and carbamates) and later diagnoses of autism and developmental delay in children. They used maps from the California Pesticide Use Report (1997-2008) and the addresses of expectant mothers to track women’s exposure to agricultural pesticide spraying during their pregnancies.

Developmental delay, in which children take extra time to reach communication, social or motor skills milestones, affects about four percent of US. kids, the authors wrote. The Centers for Disease Control and Prevention estimates that one in 68 children has an autism spectrum disorder (ASD), also marked by deficits in social interaction and language.

Of the 970 children covered by the study, 486 had an ASD, 168 had developmental delays and 316 had typical development.

"We mapped where our study participants' lived during pregnancy and around the time of birth. In California, pesticide applicators must report what they're applying, where they're applying it, dates when the applications were made and how much was applied," principal investigator Irva Hertz-Picciotto, a MIND Institute researcher and professor and vice chair of the Department of Public Health Sciences at UC Davis, said in a statement (http://www.eurekalert.org/pub_releases/2014-06/uoc--sfa061014.php). "What we saw were several classes of pesticides more commonly applied near residences of mothers whose children developed autism or had delayed cognitive or other skills."

The Northern California-based Childhood Risk of Autism from Genetics and the Environment (CHARGE) Study was published online in Environmental Health Perspectives. It found that approximately one-third of the study participants lived in “close proximity” (just under one mile) of commercial pesticide application sites.

“This study of ASD strengthens the evidence linking neurodevelopmental disorders with gestational pesticide exposures, and particularly, organophosphates and provides novel results of ASD and DD associations with, respectively, pyrethroids and carbamates,” the researchers said in the study (http://ehp.niehs.nih.gov/wp-content/uploads/advpub/2014/6/ehp.1307044.pdf).

Proximity to organophosphates at some point during gestation was associated with a 60 percent increased risk for ASD, researchers said. Many insecticides are organophosphates, which kill insects by disrupting their brains and nervous systems.

"Many of these compounds work on neurons. When they work on the insect, they're dealing with the nervous system of the insect and basically incapacitating it," Hertz-Picciotto said to HealthDay Reporter.

Autism risk was also increased with exposure to so-called pyrethroid insecticides, as was the risk for developmental delay. Pyrethroids are often sprayed to kill mosquitoes to prevent the spread of West Nile virus, and are similar to the natural pesticide pyrethrum, which is produced by chrysanthemum flowers. Because of the link to mums, this class of insecticides can sometimes be labeled as “all natural,” Hertz-Picciotto told HealthDay.

"It's a synthetic product that's been designed to be more toxic than the natural product it's imitating," she said.

Carbamate pesticides were linked to developmental delay but not ASDs, the study found. Carbamates are commonly used as surface sprays or baits in the control of household pests.

The study did not measure airborne pesticide levels, but Dr. Philip J. Landrigan, the director of the Children's Environmental Health Center at the Icahn School of Medicine at Mount Sinai in New York and who was not involved in the CHARGE Study, speculated that the pesticides probably drifted from crops through the air.

“We already knew from animal studies as well as from epidemiologic studies of women and children that prenatal exposure (to pesticides) is associated with lower IQ,” Landrigan told Reuters Health. “This study builds on that, uses the population of a whole state, looks at multiple different pesticides and finds a pattern of wide association between pesticide exposure and developmental disability.”

“While we still must investigate whether certain sub-groups are more vulnerable to exposures to these compounds than others, the message is very clear: Women who are pregnant should take special care to avoid contact with agricultural chemicals whenever possible," lead author Janie F. Shelton, from the University of California, Davis, said in the statement.

In an email to Reuters Health, Shelton said scientists need to do more research before they can say that pesticides cause autism, but, because pesticides all affect signaling between cells in the nervous system, a direct link is plausible. “Ours is the third study to specifically link autism spectrum disorders to pesticide exposure, whereas more papers have demonstrated links with developmental delay,” she said.

Hertz-Picciotto and Landrigan recommend limiting exposure to neurotoxins by not using insecticides containing organophosphates or pyrethroids in the months before and during pregnancy.

"I think it’s an area that people do need to think about, both at the individual level…if they can make some choices, it may be worth it to them," Hertz-Picciotto said to Newsweek (http://www.newsweek.com/autism-risk-much-higher-children-pregnant-women-living-near-agricultural-pesticide-255893). "I don’t use chemical pesticides that are toxic. I know it takes sometimes a little longer. I’m willing to live with those extra couple days when there might be creepy crawly things."


QTk3SnXpf3s

Hervé
30th June 2014, 14:26
Scientific Evidence Suggests The Vaccine-Autism Link Can No Longer Be Ignored (http://www.collective-evolution.com/2013/09/12/22-medical-studies-that-show-vaccines-can-cause-autism/)

September 12, 2013 by Arjun Walia (http://www.collective-evolution.com/author/arjun/).


http://cdn3.collective-evolution.com/assets/uploads/2013/09/Vaccine-child-300x196.png


Concerns regarding vaccinations continue to increase exponentially in light of all of the information and documentation that has surfaced over the past few years. As a result, corporate media has responded to alternative media, stating that the increase of persons who are choosing to opt out of vaccines and the recommended vaccine schedule is a result of ‘fear mongering.’ This may not be too surprising as the corporate media is owned by the major vaccine manufacturers, and the major vaccine manufacturers are owned by corporate media(1) (http://investors.morningstar.com/ownership/shareholders-major.html?t=GSK)(2) (http://finance.yahoo.com/q/mh?s=twx+Major+Holders)(3) (http://finance.yahoo.com/q/mh?s=ge+Major+Holders)(4) (http://finance.yahoo.com/q/mh?s=pfe+Major+Holders). Given this fact, it’s easy to fathom the possibility that these institutions are desperately trying to protect the reputation of their product.

For example, if we take a look at GlaxoSmithKline and Pfizer, they are owned by the same financial institutions and groups that own Time Warner (CNN, HBO etc.) and General Electric (NBC, Comcast, Universal Pictures etc.).(1)(2)(3)(4) This is seen throughout all of the major vaccine manufacturers and all of the 6 corporations that control our mainstream media. Keep in mind that these are the major funders of all ‘medical research’ that’s used to administer drugs and vaccinations. Despite these connections, medical research and documentation exists to show that vaccines might indeed be a cause for concern.

Vaccines and Autism, Both Sides of The Coin
Here we will simply present information from both sides of the coin because many are not even aware that two sides exist. We’ve presented multiple studies, citing multiple research papers and published research conducted by doctors and Universities from all across the world. Here (http://www.ecomed.org.uk/wp-content/uploads/2011/09/3-tomljenovic.pdf) is an example of a paper that describes how vaccine manufactures and medical ‘experts’ with drug industry connections have been aware of the multiple dangers associated with vaccinations for over 30 years. We’d also like to present medical research that indicates the many dangers associated with vaccines, and have done this on multiple occasions. We do this because the safety of vaccinations is commonly pushed by the mainstream media, without ever mentioning or citing the abundant medical research that should also be taken into consideration when discussing vaccinations. Please keep in mind that there is evidence on both sides. At the same time, some of the evidence on the side that negates a positive outlook on vaccination has been labelled fraudulent, but then again many haven’t.

The vaccine-autism debate has been going on for years. It has been a tale of shifting beliefs as child vaccination rates remain high. On February 1998, Andrew Wakefield, a British gastroenterologist and his colleagues published a paper that supposedly linked Autism to Vaccines(5) (http://cid.oxfordjournals.org/content/48/4/456.full). More specifically, he claimed that the MMR vaccine was responsible for intestinal inflammation that led to translocation of usually non-permeable peptides to the bloodstream and, subsequently, to the brain, where they affected development(5). His work was unpublished, and he lost his medical license despite the fact multiple studies seem to support Andrew Wakefield’s work (here (http://vran.org/wp-content/documents/VRAN-Abnormal%20Measles-Mumps-Rubella-Antibodies-CNS-Autoimmunity-Children-Autism-Singh-Lin-Newell-Nelson.pdf) is one example, and here (http://www.mdpi.com/1099-4300/14/11/2227) is another.) He has been labelled a fraud by the mainstream medical world, some experts claim that his research and methods are weak and based on very little evidence. Dr Wakefield’s research will NOT be used in this article.

At the same time I must mention that multiple studies from around the world have concluded that there is no link between Autism and the MMR Vaccine(5). It can become quite a confusing subject given that we have multiple medical studies contradicting each other. Was Dr. Wakefield exposing something that the medical industry did not want you to know? It is known that vaccine manufacturers suppress harmful data regarding their product, as mentioned and illustrated earlier in the article. Regardless of the MMR vaccine and autism debate, there are still a number of studies that link vaccines to a possible autism connection. Please keep in mind that multiple courts worldwide have ruled in favour of vaccines causing autism, brain damage and other complications (6)(7), that include the MMR vaccine.

Here is a great video narrated by Rob Schneider (http://www.collective-evolution.com/2012/09/07/rob-schneider-speaks-out-against-vaccines/) outlining the vaccine-autsim link. Below that you will find a list of 22 medical studies that show possible connections to vaccines and autism. Please keep in mind that we’ve only presented 22 studies here, there are many more published papers that document the link. Hopefully this inspires you to further your research on the subject. Also keep in mind that Autism is only one of the multiple shown consequences of vaccine administration, as they have been linked to a number of other ailments.


6S1-LgYyjQg

1. A study published in the Journal Annals of Epidemiology (http://www.ncbi.nlm.nih.gov/pubmed/21058170) has shown that giving the Hepatitis B vaccine to newborn baby boys could triple the risk of developing an autism spectrum disorder compared to boys who were not vaccinated as neonates. The research was conducted at Stony Brook University Medical Centre, NY.

2. A study published in the (http://omsj.org/reports/tomljenovic%202011.pdf)Journal of Inorganic Biochemistry (http://omsj.org/reports/tomljenovic%202011.pdf) by researchers at the Neural Dynamics Group, Department of Ophthalmology and Visual Sciences at the University of British Columbia determined that Aluminum, a highly neurotoxic metal and the most commonly used vaccine adjuvant may be a significant contributing factor to the rising prevalence of ASD in the Western World. They showed that the correlation between ASD prevalence and the Aluminum adjuvant exposure appears to be the highest at 3-4 months of age. The studies also show that children from countries with the highest ASD appear to have a much higher exposure to Aluminum from vaccines. The study points out that several prominent milestones of brain development coincide with major vaccination periods for infants. These include the onset of synaptogenesis (birth), maximal growth velocity of the hippocampus and the onset of amygdala maturation. Furthermore, major developmental transition in many bio-behavioural symptoms such as sleep, temperature regulation, respiration and brain wave patterns, all of which are regulated by the neuroendocrine network. Many of these aspects of brain function are known to be impaired in autism, such as sleeping and brain wave patterns.
According to the FDA, vaccines represent a special category of drugs as they are generally given to healthy individuals. Further according to the FDA, “this places significant emphasis on their vaccine safety”. While the FDA does set an upper limit for Aluminum in vaccines at no more that 850/mg/dose, it is important to note that this amount was selected empirically from data showing that Aluminum in such amounts enhanced the antigenicity of the vaccine, rather than from existing safety. Given that the scientific evidence appears to indicate that vaccine safety is not as firmly established as often believed, it would seem ill advised to exclude paediatric vaccinations as a possible cause of adverse long-term neurodevelopment outcomes , including those associated with autism.
3. A study published in the (http://www.ncbi.nlm.nih.gov/pubmed/21623535) Journal of Toxicology and Environmental Health, Part A: Current Issues (http://www.ncbi.nlm.nih.gov/pubmed/21623535) by the Department of Economics and Finance at the University of New York shows how researchers suspect one or more environmental triggers are needed to develop autism, regardless of whether individuals have a genetic predisposition or not. They determined that one of those triggers might be the “battery of vaccinations that young children receive.” Researchers found a positive and statistically significant relationship between autism and vaccinations. They determined that the higher the proportion of children receiving recommended vaccinations, the higher the prevalence of autism. A 1 % increase in vaccination was associated with an additional 680 children having autism. The results suggest that vaccines may be linked to autism and encourages more in depth study before continually administering these vaccines.

4. A study published in the (http://www.hindawi.com/journals/jt/2013/801517/)Journal of Toxicology (http://www.hindawi.com/journals/jt/2013/801517/) by the Department of Neurosurgery at The Methodist Neurological Institute in Houston has shown that ASD is a disorder caused by a problem in brain development. They looked at B-cells and their sensitivity levels to thimerosal, a commonly used additive in many vaccines. They determined that ASD patients have a heightened sensitivity to thimerosal which would restrict cell proliferation that is typically found after vaccination. The research shows that individuals who have this hypersensitivity to thimerosal could make them highly susceptible to toxins like thimerosal, and that individuals with a mild mitochondrial defect may be affected by thimerosal. The fact that ASD patients’ B cells exhibit hypersensitivity to thimerosal tells us something.

5. A study published in the Journal of Biomedical Sciences (http://www.ncbi.nlm.nih.gov/pubmed/12145534)determined that the autoimmunity to the central nervous system may play a causal role in autism. Researchers discovered that because many autistic children harbour elevated levels of measles antibodies, they should conduct a serological study of measles-mumps-rubella (MMR) and myelin basic protein (MBP) autoantibodies. They used serum samples of 125 autistic children and 92 controlled children. Their analysis showed a significant increase in the level of MMR antibodies in autistic children. The study concludes that the autistic children had an inappropriate or abnormal antibody response to MMR. The study determined that autism could be a result from an atypical measles infection that produces neurological symptoms in some children. The source of this virus could be a variant of MV, or it could be the MMR vaccine.

6. Study published in the (http://www.collective-evolution.com/2013/09/12/22-medical-studies-that-show-vaccines-can-cause-autism/Study%20published%20in%20the%20Annals%20of%20Clinical%20Psychiatry)Annals of Clinical Psychiatry (http://www.collective-evolution.com/2013/09/12/22-medical-studies-that-show-vaccines-can-cause-autism/Study%20published%20in%20the%20Annals%20of%20Clinical%20Psychiatry) suggests that Autism is likely triggered by a virus, and that measles virus (MV and/or MMR vaccine) might be a very good candidate. It supports the hypothesis that a virus-dincued autoimmune response may play a causal role in autism.

7. A study published in the (http://ajcn.nutrition.org/content/80/6/1611.full)American Journal of Clinical Nutrition (http://ajcn.nutrition.org/content/80/6/1611.full) determined that an increased vulnerability to oxidative stress and decreased capacity for methylation may contribute to the development and clinical manifestation of autism. It’s well known that viral infections cause increased oxidative stress. Research suggests (http://www.ncbi.nlm.nih.gov/pubmed/11895129) that metals, including those found in many vaccines are directly involved in increasing oxidative stress.

8. A study published by the Department of Pharmaceutical Sciences (http://www.ncbi.nlm.nih.gov/pubmed/14745455) at Northeastern University, Boston determined that a novel growth factor signalling pathway that regulates methionine synthase(MS) activity and thereby modulates methylation reactions. The potent inhibition of this pathway by ethanol, lead, mercury, aluminum and thimerosal suggests that it may be an important target of neurodevelopmental toxins. You can read more about this here (http://legacy.autism.com/medical/research/deth.htm), and here (https://imfar.confex.com/imfar/2010/webprogram/Paper5280.html). You can read more about the MS/autism link here (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0056927)

9. A study published in the Journal of Child Neurology (http://jcn.sagepub.com/content/22/11/1308.abstract)examined the question of what is leading to the apparent increase in autism. They expressed that if there is any link between autism and mercury, it is crucial that the first reports of the question are not falsely stating that no link occurs. Researchers determined that a significant relation does exist between the blood levels of mercury and the diagnosis of an autism spectrum disorder.

10. A study published in the (http://jcn.sagepub.com/content/21/2/170.abstract) Journal of Child Neurology (http://jcn.sagepub.com/content/21/2/170.abstract) noted that autistic spectrum disorders can be associated with mitochondrial dysfunction. Researchers determined that children who have mitochondrial-related dysfunctional cellular energy metabolism might be more prone to undergo autistic regression between 18 and 30 months of age if they also have infections or immunizations at the same time.

11. A study conducted by Massachusetts General Hospital (http://www.ncbi.nlm.nih.gov/pubmed/16151044) at the Centre for Morphometric Analysis by the department of Paediatric Neurology illustrates how autistic brains have a growth spurt shortly after birth and then slow in growth a few short years later. Researchers have determined that neuroinflammation appears to be present in autistic brain tissue from childhood through adulthood. The study excerpt reads:
Oxidative stress, brain inflammation and microgliosis have been much documented in association with toxic exposures including various heavy metals. The awareness that the brain as well as medical conditions of children with autism may be conditioned by chronic biomedical abnormalities such as inflammation opens the possibility that meaningful biomedical interventions may be possible well past the window of maximal neuroplasticity in early childhood because the basis for assuming that all deficits can be attributed to fixed early developmental alterations in net
12, A study conducted by the Department of Paediatrics at the University of Arkansas (http://www.ncbi.nlm.nih.gov/pubmed/15527868) determined that thimerosal-induced cytotoxicity was associated with the depletion of intracellular glutathione (GSH) in both cell lines. The study outlines how many vaccines have been neurotoxic, especially to the developing brain. Depletion of GSH is commonly associated with autism. Although thimerosal has been removed from most children’s vaccines, it is still present in flu vaccines given to pregnant women, the elderly and to children in developing countries.

13. A study published in the (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0068444)Public Library of Science (PLOS) (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0068444) determined that elevation in peripheral oxidative stress is consistent with, and may contribute to more severe functional impairments in the ASD group. We know that oxidative stress is triggered by heavy metals, like the ones contained in multiple vaccines.

14. A study conducted by the University of Texas Health Science Centre (http://www.ncbi.nlm.nih.gov/pubmed/16338635) by the Department of Family and Community Medicine determined that for each 1,000 Ib of environmentally released mercury, there was a 43% increase in the rate of special education services and a 61% increase in the rate of autism. Researchers emphasized that further research was needed regarding the association between environmentally released mercury and developmental disorders such as autism.

15. A study published in the International Journal of Toxicology (http://www.ncbi.nlm.nih.gov/pubmed/12933322) determined that in light of the biological plausibility of mercury’s role in neurodevelopment disorders, the present study provides further insight into one possible mechanism by which early mercury exposures could increase the risk of autism.

16. A study published in the (http://www.ncbi.nlm.nih.gov/pubmed/17454560)Journal of Toxicology and Environmental Health (http://www.ncbi.nlm.nih.gov/pubmed/17454560) determined that mercury exposure can induce immune, sensory, neurological, motor and behavioural dysfunctions similar to traits defining or associated with ASDs. Based upon differential diagnoses, 8 of 9 patients examined were exposed to significant mercury from Thimerosal-containing vaccine preparations during their fetal/infant developmental periods. These previously normal developing children suffered mercury encephalopathies that manifested with clinical symptoms consistent with regressive ASDs. Evidence for mercury intoxication should be considered in the differential diagnosis as contributing to some regressive ASDs.

17. A study published by the US National Library of Medicine (http://civileats.com/wp-content/uploads/2009/01/palmer2008.pdf)conducted by the University of Texas Health Science Centre suspected that persistent low-dose exposures to various environmental toxicants including mercury, that occur during critical windows of neural development among genetically susceptible children, may increase the risk for developmental disorders such as autism.

18. A study conducted by the Department of Obstetrics and Gynaecology (http://www.ane.pl/pdf/7020.pdf) at University of Pittsburgh’s School of Medicine showed that Macaques are commonly used in pre-clinical vaccine safety testing. Collective Evolution does not support animals testing, we feel there is a large amount of evidence and research that already indicated the links to vaccines in which some animals have been used to illustrate. The objective of this study was to compare early infant cognition and behaviour with amygdala size and opioid binding in rhesus macaques receiving the recommended childhood vaccines. The animal model, which examines for the first time, behavioural, functional and neuromorphometric consequences of the childhood vaccine regimen, mimics certain neurological abnormalities of autism. These findings raise important safety issues while providing a potential model for examining aspects of causation and disease pathogenesis in acquired disorders of behaviour and development.

19. A study conducted by The George Washington University School of Public Health (http://www.ncbi.nlm.nih.gov/pubmed/18482737) from the Department of Epidemiology and Biostatistics determined that significantly increased rate ratios were observed for autism and autism spectrum disorders as a result of exposure to mercury from Thimerosal-containing vaccines.

20. A study published in the Journal Cell Biology and Toxicology (http://www.ncbi.nlm.nih.gov/pubmed/19357975) by Kinki University in Osaka, Japan determined that in combination with the brain pathology observed in patients diagnosed with autism, the present study helps to support the possible biological plausability for how low-dose exposure to mercury from thimerosal-containing vaccines may be associated with autism.

21. A study published by the (http://labmed.ascpjournals.org/content/33/9/708.full.pdf) Journal Lab Medicine (http://labmed.ascpjournals.org/content/33/9/708.full.pdf) determined that vaccinations may be one of the triggers for autism. Researchers discovered that substantial data demonstrates immune abnormality in many autistic children consistent with impaired resistance to infection, activation of inflammatory responses and autoimmunity. Impaired resistance may predispose to vaccine injury in autism.

22. A study published in the Journal (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/?tool=pubmed)Neurochemical Research (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/?tool=pubmed) determined that since excessive accumulation of extracellular glutamate is linked with excitotoxicity, data implies that neonatal exposure to thimerosal-containing vaccines might induce excitotoxic brain injuries, leading to neurodevelopmental disorders.


Sources:
All sources not listed below are listed throughout the article and highlighted. To view them, please click on them.
(1)http://investors.morningstar.com/ownership/shareholders-major.html?t=GSK

(2)http://finance.yahoo.com/q/mh?s=twx+Major+Holders

(3) (http://finance.yahoo.com/q/mh?s=ge+Major+Holders)http://finance.yahoo.com/q/mh?s=ge+Major+Holders

(4) http://finance.yahoo.com/q/mh?s=pfe+Major+Holders

(5) (http://cid.oxfordjournals.org/content/48/4/456.full)http://cid.oxfordjournals.org/content/48/4/456.full

(6) (http://www.ebcala.org/unanswered-questions) http://www.ebcala.org/unanswered-questions

(7)http://www.collective-evolution.com/2013/07/07/courts-rule-mmr-thimerosal-containing-vaccines-caused-autism-brain-damage/

Tesla_WTC_Solution
3rd July 2014, 22:04
Thank you Amzer Zo! :)

p.s.

http://sfari.org/news-and-opinion/news/2013/large-study-links-autism-to-autoimmune-disease-in-mothers


Large study links autism to autoimmune disease in mothers

Sarah DeWeerdt
22 August 2013

Brain-bound: Immune molecules in mothers who have children with autism target neurons in the frontal cortex, cerebellum and hippocampus of mouse brains.

About one in ten women who have a child with autism have immune molecules in their bloodstream that react with proteins in the brain, according to a study published 20 August in Molecular Psychiatry1.

Several research groups have found these immune molecules, called antibodies, in mothers of children with autism, and have shown that prenatal exposure to the antibodies alters social behavior in mice and monkeys.

The new study, which includes more than 2,700 mothers of children with autism, is the largest survey yet on the prevalence of these anti-brain antibodies.

“It’s a very large sample size,” says study leader Betty Diamond, head of the Center for Autoimmune and Musculoskeletal Disorders at The Feinstein Institute for Medical Research in Long Island, New York. The scale gives a clearer impression of the prevalence of these antibodies, she says.

Antibodies help the body’s immune system recognize and fight off disease-causing microorganisms such as bacteria and viruses, but sometimes the body mistakenly produces antibodies to its own proteins. In some people, this results in autoimmune diseases such as rheumatoid arthritis and lupus, in which the body attacks its own tissues.

Researchers say anti-brain antibodies do not harm the brains of the women who produce them because of the blood-brain barrier, a filter that prevents most molecules from entering the brain. But the immature blood-brain barrier of a developing fetus may let them through, allowing them to damage the brain and perhaps cause autism.

Diamond’s team also found that women who have autism-linked antibodies are more likely to have other markers of autoimmunity compared with those who don’t carry these antibodies. Studies have shown that women with an autoimmune disease also have an increased risk of having a child with autism2.

“This ties together the epidemiological finding that women who have autoimmune disease are more likely to have kids with autism, with the idea that there are actually antibodies against fetal brain in their serum,” says Paul Patterson, professor of biology at the California Institute of Technology, who was not involved in the work.


Patterson notes that the researchers tested binding of the antibodies to adult mouse brain, but protein expression in the adult brain is often very different from that in the fetal brain. “Optimally, one would like to know what the binding is to fetal human brain or fetal monkey brain,” he says.

According to Diamond, the team did find that the antibodies also bind to fetal human brain extracts and to whole fetal mouse brain. However, she says, it wasn’t possible to see which regions of fetal mouse brain they bind to because the brains are too small.

Her team performed several other analyses that uncovered tantalizing links between autism-linked antibodies and autoimmunity more generally.

First, they screened the blood of study participants for anti-nuclear antibodies (ANAs), which bind to molecules found in the cell nucleus and are commonly found in people with a variety of different autoimmune disorders. They found that 52 percent of autism mothers who carry anti-brain antibodies also have ANAs. In contrast, only 13.4 percent of autism mothers without anti-brain antibodies have ANAs, as do 15 percent of controls.

Mothers with anti-brain antibodies are also more likely to have autoimmune diseases, especially rheumatoid arthritis and lupus, compared with mothers who don’t have these antibodies.

Finally, the team screened a group of 363 women with rheumatoid arthritis for autism-linked antibodies. They found that 13.5 percent of these women have anti-brain antibodies, similar to the prevalence among mothers of children with autism and much higher than that of controls.

That’s a rather puzzling finding, Patterson says. “If they’re just as likely to be found in rheumatoid arthritis women, that means they’re not especially specific to autism,” he says.

But a link between rheumatoid arthritis and autism isn’t unheard of, Diamond says. In a separate series of experiments, she has found that antibodies that cause kidney damage in women with lupus also cause cognitive impairment in mice exposed to the antibodies in utero4.

Diamond says she has unpublished data indicating that some of the brain proteins that bind the antibodies are already implicated in autism or other neurodevelopmental disorders — but declined to reveal details. Are any of the targets she has identified the same as those reported by Van de Water and her colleagues in July? “It’s sort of interesting,” Diamond says. “They’re not.”

News and Opinion articles on SFARI.org are editorially independent of the Simons Foundation.

http://www.ncbi.nlm.nih.gov/pubmed/23318464


Behav Brain Res. 2013 Apr 15;243:138-45. doi: 10.1016/j.bbr.2012.12.062. Epub 2013 Jan 11.
Heparan sulfate deficiency in autistic postmortem brain tissue from the subventricular zone of the lateral ventricles.
Pearson BL1, Corley MJ, Vasconcellos A, Blanchard DC, Blanchard RJ.
Author information
Abstract

Abnormal cellular growth and organization have been characterized in postmortem tissue from brains of autistic individuals, suggestive of pathology in a critical neurogenic niche, the subventricular zone (SVZ) of the brain lateral ventricles (LV). We examined cellular organization, cell proliferation, and constituents of the extracellular matrix such as N-sulfated heparan sulfate (HS) and laminin (LAM) in postmortem brain tissue from the LV-SVZ of young to elderly individuals with autism (n=4) and age-matched typically developing (TD) individuals (n=4) using immunofluorescence techniques. Strong and systematic reductions in HS immunofluorescence were observed in the LV-SVZ of the TD individuals with increasing age. For young through mature, but not elderly, autistic pair members, HS was reduced compared to their matched TDs. Cellular proliferation (Ki67+) was higher in the autistic individual of the youngest age-matched pair. These preliminary data suggesting that HS may be reduced in young to mature autistic individuals are in agreement with previous findings from the BTBR T+tf/J mouse, an animal model of autism; from mice with genetic modifications reducing HS; and with genetic variants in HS-related genes in autism. They suggest that aberrant extracellular matrix glycosaminoglycan function localized to the subventricular zone of the lateral ventricles may be a biomarker for autism, and potentially involved in the etiology of the disorder.

Copyright © 2013 Elsevier B.V. All rights reserved.

PMID:
23318464
[PubMed - indexed for MEDLINE]
PMCID:
PMC3594061

Free PMC Article

http://en.wikipedia.org/wiki/Glucosamine
http://en.wikipedia.org/wiki/Heparan_sulfate


Heparan sulfate (HS) is a linear polysaccharide found in all animal tissues. It occurs as a proteoglycan (HSPG) in which two or three HS chains are attached in close proximity to cell surface or extracellular matrix proteins.[1][2] It is in this form that HS binds to a variety of protein ligands and regulates a wide variety of biological activities, including developmental processes, angiogenesis, blood coagulation and tumour metastasis. HS has been shown to serve as cellular receptor for a number of viruses including the respiratory syncytial virus (Hallak et al. 2000)

more on heparan sulfate:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416335/

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342043/

panopticon
5th August 2014, 11:19
j2kx4HF4PY0
-- Pan

Tesla_WTC_Solution
5th August 2014, 13:35
Panopticon that is really remarkable.
I woke up this morning thinking about the fetal brain antibodies in the moms.
I've been having some morning sickness and can't stop worrying about autism.

:(

p.s. at least the dolphins can help!!! people messed everything up

Flash
20th August 2014, 17:24
http://www.youtube.com/watch?v=LhpckzxVEoc

This video is in some other threads but has definitely its place here as well. Younger years of exposure to MMR associated with higher risks of autism - 300 % more risk if vaccines on time versus later in life - and CDC has concealed it - and it is almost double risk in black boy children.

It pis ses me off literally. Hundreds of thousands of dollars I have spent to recuperate my daughter, plus true time sacrifice and life sacrifice (no boyfriend for years being much too busy with work and specialists/natural doctors appointments) for my child who was on the light side of the Spectrum (dysphasia is on the Spectrum of autism). I have seen so many parents and children whose life has been ruined with autism.

Hervé
22nd August 2014, 10:44
Breaking: MMR vaccine, autism, CDC coverup (http://jonrappoport.wordpress.com/2014/08/20/breaking-mmr-vaccine-autism-cdc-coverup/)

Aug20, 2014 (http://jonrappoport.wordpress.com/2014/08/20/breaking-mmr-vaccine-autism-cdc-coverup/) by Jon Rappoport (http://jonrappoport.wordpress.com/author/jonrappoport/)
www.nomorefakenews.com (http://www.nomorefakenews.com/)

Sources: Age of Autism, Focus Autism Foundation—
Age of Autism 8/18 article: “Senior government scientist breaks 13 years’ silence on CDC’s vaccine-autism fraud.” (http://www.ageofautism.com/2014/08/senior-government-scientist-breaks-13-years-silence-on-cdcs-vaccine-autism-fraud.html)

CDC research scientist comes forward, anonymously, comes clean, tells Dr. Brian Hooker that the CDC has known about the MMR vaccine connection to autism for at least 11 years.

Has known, and has intentionally covered it up.

The CDC and the US government have gone to extreme lengths to assert there is no vaccine-autism connection.

This CDC scientist has spoken with Brian Hooker, a PhD in biochemical engineering, many times.

Hooker states he has seen raw CDC data not included in any study. And the data show that:

African-American boys who receive their first MMR (measles, mumps, rubella) vaccine before the age of 36 months have a 300% increased risk for autism.

If this is true, what else is the CDC hiding?

From the Age of Autism article (8/18): “Dr. Hooker has worked closely with the CDC whistleblower, and he viewed highly sensitive documents related to the [fraudulent government] study via Congressional request from U.S. Representative Darrell Issa, Chairman of the House Oversight and Government Reform Committee. The CDC documents from Congress and discussions that Hooker had with the whistleblower reveal widespread manipulation of scientific data and top-down pressure on CDC scientists to support fraudulent application of government policies on vaccine safety.”

If all this is true, then the CDC has stood by for the last decade and done nothing, while the MMR vaccine has damaged the brains of many, many children.

You may recall that Dr. Andrew Wakefield pointed out a likely connection between the MMR vaccine and autism. British authorities and the CDC destroyed his career.

Wakefield now states: “Over a decade ago, Dr. Scott Montgomery and I put forward a hypothesis for MMR vaccine and autism: the age you receive the vaccine influences the risk. …We shared this hypothesis with vaccine officials, members of the Centers for Disease Control, at meetings in Washington, D.C. and Cold Spring Harbor. A group of senior vaccine safety people at the CDC studied it. It panned out. We were right–at least partly. By Nov 9, 2001, nearly thirteen years ago, senior CDC scientists knew that the younger age exposure to MMR was associated with an increased risk of autism. In 2004 they published, but they hid the results. …”

There is another angle on all this. It has to do with how diseases and disorders are labeled and defined.

There is no definitive test for autism. The criteria for diagnosis are a menu of behaviors. Therefore, we are looking at a wide net which includes all sorts of brain and neurological damage.

Official studies are done which “show” that some cases of what’s called autism are not preceded by vaccination—and therefore, vaccines couldn’t be “the single cause of the single disease called autism.”

That proof, of course, is completely false—because what’s called autism isn’t a single disease. It’s neurological damage, which can have a number of causes.

And now we are looking at one of those causes: the MMR vaccine.

If in the coming days, the CDC claims they’ve already eliminated the possibility that vaccines are the cause of autism, you’ll understand their shell game, their con, their ruse.

They’ve stacked the deck, so they can roll out so-called cases of autism which have no connection to the MMR vaccine.

It’s hoax by labels and semantics.

While vaccines continue to damage the brains of children.

(This story continues here (http://jonrappoport.wordpress.com/2014/08/20/do-we-have-a-medical-edward-snowden/).)

Jon Rappoport

Daphne
22nd August 2014, 12:47
It pis ses me off literally. Hundreds of thousands of dollars I have spent to recuperate my daughter, plus true time sacrifice and life sacrifice (no boyfriend for years being much too busy with work and specialists/natural doctors appointments) for my child who was on the light side of the Spectrum (dysphasia is on the Spectrum of autism). I have seen so many parents and children whose life has been ruined with autism.

I saw this excellent video and must add that LENS neurofeedback and cannabis can be helpful for autism symptoms.

vilcabamba
25th August 2014, 15:47
I think nanotechnology is involved In autism. Nanobots feel like bugs crawling up and down the skin and that is how I heard an autistic girl describe the feeling In her body. The nano breaks down into ammonia which causes brain inflammation and can drug the brain like the same feeling with alcohol where you are out of it all the time. Nanotechnology can be broken down with herbs and essential oils like orange and citrus oils depending on which ones they used. They change the consistency of nano all the time..it used to be silicones and and now it's Teflon and diamonds. If someone wants to test their child to see if it's nanotechnology or other viruses causing the autism I recommend the lab testing from Integrative Health Systems in Los Angeles on Larchmont blvd. The woman is a toxicologist who can do much more then an M.D. can in regards to testing for poisons such as nanotechnology and other chemicals. Although, due to the PHD scientist who runs this place being ahead of the curb and a whistleblower, she makes everyone sign a consent form from their regular M.D. before she can run the blood tests since the PTB watch her and would love to silence her b/c she was a former insider with knowledge about what poisons people are exposed to and she knows how to detox them as she was a biowarfare scientist who created antidotes for poisons. She did my lab tests and I called her from NJ as I was sick from chemtrails and she has great detoxification equipment that I use almost every night for the past 6 years.

Tesla_WTC_Solution
25th August 2014, 17:06
you know what? autistic kids DO have high levels of brain damaging ammonia in their blood...

it's interesting that you point this out. Michael Crichton could have learned something from you.

Tesla_WTC_Solution
26th August 2014, 19:27
Didn't think we would have to fight this battle on our own forum again this year, but we have some unbelievers.

For those of you who insist on spreading the OPINION that vaccines cannot contribute to autism symptoms,
I did find a copy of the 1990s letter written by US school nurses to Congress regarding the probability that Hepatitis B is CAUSING an influx of damaged children to the US school system.

http://www.cssa-inc.org/Articles/Hepatitis_B.htm



Hepatitis B Vaccine Hearings: A School Nurse Perspective

To the Subcommittee on Criminal Justice, Drug Policy, and Human Resources of the Committee on Government Reform,
U.S. House of Representatives
May 17, 1999

Mr. Chairman and Members of the Subcommittee:

This is a school nursing perspective for the congressional hearings to be held on May 18, 1999 regarding the safety of the hepatitis B vaccine that is being mandated for newborns and now older children in America. We ask you to please consider the following information and submit it into the congressional testimony. As nurses we continually see more and more damaged children entering our schools, and we are very concerned that a major portion of that damage may be due to the hepatitis B vaccine’s assault on the newborn neurological and immune system.

My name is Patti White, R.N. I am a registered professional nurse and the district health services coordinator for a multi-school district. I am writing on behalf of the school nurses in our district. We have very grave concerns about the hepatitis B vaccine.




Also I wanted to share the letter co-written by Vice President Joe Biden prior to his election, regarding the massive amount of vaccine-related injury suffered by US and UK troops after being forced to take the experimental Anthrax Vaccine.

Project Bioshield a Failure and sham


http://www.nvic.org/Downloads/bioshiled-letter.aspx




I am not gonna call out people by name but I am gonna call wrong wrong.

Hervé
26th August 2014, 20:06
Didn't think we would have to fight this battle on our own forum again this year, but we have some unbelievers.

[...]

I am not gonna call out people by name but I am gonna call wrong wrong.

Check this post and the thread it's in: http://projectavalon.net/forum4/showthread.php?74107-Breaking-CDC-whistleblower-Thompson-in-grave-danger-now&p=869126&viewfull=1#post869126

avid
27th August 2014, 07:33
...........

Hervé
5th September 2014, 16:06
Bombshell: CDC whistleblower goes further: mercury causes autism (https://jonrappoport.wordpress.com/2014/09/04/bombshell-cdc-whistleblower-goes-further-mercury-causes-autism/)

Sep 4 (https://jonrappoport.wordpress.com/2014/09/04/bombshell-cdc-whistleblower-goes-further-mercury-causes-autism/), 2014 by Jon Rappoport (https://jonrappoport.wordpress.com/author/jonrappoport/)
www.nomorefakenews.com (http://www.nomorefakenews.com/)

The brief explosive video is posted at autismmediachannel.com on the home page: “CDC Whistleblower William Thompson on Thimerosal.” (http://vimeo.com/104141199)

Beyond admitting to fraud in a 2004 CDC study that exonerated the MMR vaccine, Dr. William Thompson, a CDC scientist, asserts there is a connection between mercury (thimerosal) in vaccines and autism.

Thompson states that giving a vaccine containing mercury to a pregnant woman is something he would never do.

Couched in science-speak, Thompson winds up his remarks with this: “There is biologic plausibility right now to say thimerosal causes autism-like features.”

For a scientist at the CDC to make this admission, after millions and millions of dollars have been spent by that agency and the US government to conclude mercury has no connection to autism…it’s extraordinary, to say the least.

The PR mantra declaring thimerosal safe has been repeated thousands of times by major media outlets—and now a researcher on the inside has repudiated it.

Experts and other con artists will try to parse Thompson’s words, but the meaning is clear.

Only a mindless idiot or an overt killer would inject a vaccine containing mercury into a human being.

Meanwhile, the major media blackout on Thompson’s revelations continues. The collusion in a vast crime is their mission.

CDC Whistleblower on Thimerosal in Pregnant Women (http://vimeo.com/104141199) from Autism Media Channel (http://vimeo.com/user5503203) on Vimeo (https://vimeo.com).

Jon Rappoport

Tesla_WTC_Solution
10th September 2014, 14:38
Thanks you guys. i found something interesting for some of us, there is apparently a US political party now called the "Canary Party",
and it focuses on the right of US citizens to opt out of vaccines, and spreading the TRUTH about vaccine injury and how it ruins lives.

Mail@CanaryParty.org

http://www.canaryparty.org/index.php

Also the recent Alex Jones piece:

http://www.infowars.com/special-report-how-u-s-government-admits-vaccines-cause-autism/

Tesla_WTC_Solution
17th September 2014, 16:44
Shocking even for infowars: http://www.infowars.com/dozens-of-children-dead-after-un-gives-tainted-vaccine-in-rebel-held-syria/


Dozens of Children Dead After UN Gives Tainted Vaccine in “Rebel” Held Syria
U.S. and Saudi-backed mercenaries blame al-Assad

by Kurt Nimmo | Infowars.com | September 17, 2014


A United Nations sponsored measles vaccine program in northern Syria resulted in 36 children suffering “excruciating deaths,” according to doctors in the area held by U.S. and Saudi mercenaries who are administering the program.

Infants given the poisoned vaccine experienced rapidly falling heart rates and turned blue.

Anti-Assad activists blamed the Syrian government and accused it of spiking the vaccines with cyanide. The mercenaries previously accused the Syrian government of launching a chemical weapons attack in the Damascus suburb of Ghouta. It was later discovered the so-called rebels had in fact launched the attack.

There were conflicting figures of the number of dead in the towns of Jirjanaz and Maaret al-Nouman in the northeastern province of Idlib, according to news reports.

In addition to the 36 reported deaths, dozens of other children fell seriously ill.

“At least five children have died and 50 others are suffering from poisoning or allergic reactions after measles vaccinations in Jirjanaz, in Idlib province,” the Syrian Observatory for Human Rights said.

The Syrian Observatory for Human Rights is a one-man propaganda operation run by Rami Abdulrahman, an anti-Assad activist based in London.

“It’s very bad. The figures of dead we are getting go into the 30s. Children are dying very quickly,” said the coordinator of the medical charity, Uossm. “We think it will get worse.”

The charity Save the Children said it was “appalled and deeply saddened” by the deaths.

“The local authorities have launched an investigation. It is clear something has gone badly wrong and Save the Children will help the authorities in any way we can to help find out what has happened.”

Save the Children was said to be involved in the alleged assassination of Osama bin Laden. The organization was rumored to be part of a fake vaccination program in Pakistan run by the CIA as a cover for the assassination.

Pulitzer Prize-winning journalist Seymour Hersh characterized the raid which supposedly killed Osama Bin Laden in 2011 as “one big lie.” U.S. government insider Dr. Steve R. Pieczenik and others insist Osama bin Laden died in 2001.

In 2013 the organization called for a ceasefire so the United Nations could address a polio outbreak in the eastern part of the country.

___________________________________________________



September 17, 2014
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Ex-Vaccine Developer Reveals Lies the Vaccine Industry is Built Upon in Interview

Alternative-Doctor.com

Disclaimer: Any information obtained here is not to be construed as medical OR legal advice. The decision to vaccinate and how you implement that decision is yours and yours alone.
Jon Rappaport interviews an ex-vaccine worker
“Dr Mark Randall”.

Q: You were once certain that vaccines were the hallmark of good medicine.

A: Yes I was. I helped develop a few vaccines. I won’t say which ones.

Q: Why not?

A: I want to preserve my privacy.

Q: So you think you could have problems if you came out into the open?

A: I believe I could lose my pension.

Q: On what grounds?

A: The grounds don’t matter. These people have ways of causing you problems, when you were once part of the Club. I know one or two people who were put under surveillance, who were harassed.

Q: Harassed by whom?

A: The FBI.

Q: Really?

A: Sure. The FBI used other pretexts. And the IRS can come calling too.

Q: So much for free speech.

A: I was “part of the inner circle.” If now I began to name names and make specific accusations against researchers, I could be in a world of trouble.

Q: What is at the bottom of these efforts at harassment?

A: Vaccines are the last defense of modern medicine. Vaccines are the ultimate justification for the overall “brilliance” of modern medicine.

Q: Do you believe that people should be allowed to choose whether they should get vaccines?

A: On a political level, yes. On a scientific level, people need information, so that they can choose well. It’s one thing to say choice is good. But if the atmosphere is full of lies, how can you choose? Also, if the FDA were run by honorable people, these vaccines would not be granted licenses. They would be investigated to within an inch of their lives.

Q: There are medical historians who state that the overall decline of illnesses was not due to vaccines.

A: I know. For a long time, I ignored their work.

Q: Why?

A: Because I was afraid of what I would find out. I was in the business of developing vaccines. My livelihood depended on continuing that work.

Q: And then?

A: I did my own investigation.

Q: What conclusions did you come to?

A: The decline of disease is due to improved living conditions.

Q: What conditions?

A: Cleaner water. Advanced sewage systems. Nutrition. Fresher food. A decrease in poverty. Germs may be everywhere, but when you are healthy, you don’t contract the diseases as easily.

Q: What did you feel when you completed your own investigation?

A: Despair. I realized I was working a sector based on a collection of lies.

Q: Are some vaccines more dangerous than others?

A: Yes. The DPT shot, for example. The MMR. But some lots of a vaccine are more dangerous than other lots of the same vaccine. As far as I’m concerned, all vaccines are dangerous.

Q: Why?

A: Several reasons. They involve the human immune system in a process that tends to compromise immunity. They can actually cause the disease they are supposed to prevent. They can cause other diseases than the ones they are supposed to prevent.

Q: Why are we quoted statistics which seem to prove that vaccines have been tremendously successful at wiping out diseases?

A: Why? To give the illusion that these vaccines are useful. If a vaccine suppresses visible symptoms of a disease like measles, everyone assumes that the vaccine is a success. But, under the surface, the vaccine can harm the immune system itself. And if it causes other diseases — say, meningitis — that fact is masked, because no one believes that the vaccine can do that. The connection is overlooked.

Q: It is said that the smallpox vaccine wiped out smallpox in England.

A: Yes. But when you study the available statistics, you get another picture.

Q: Which is?

A: There were cities in England where people who were not vaccinated did not get smallpox. There were places where people who were vaccinated experienced smallpox epidemics. And smallpox was already on the decline before the vaccine was introduced.

Q: So you’re saying that we have been treated to a false history.

A: Yes. That’s exactly what I’m saying. This is a history that has been cooked up to convince people that vaccines are invariably safe and effective.

Q: Now, you worked in labs. Where purity was an issue.

A: The public believes that these labs, these manufacturing facilities are the cleanest places in the world. That is not true. Contamination occurs all the time. You get all sorts of debris introduced into vaccines.

Q: For example, the SV40 monkey virus slips into the polio vaccine.

A: Well yes, that happened. But that’s not what I mean. The SV40 got into the polio vaccine because the vaccine was made by using monkey kidneys. But I’m talking about something else. The actual lab conditions. The mistakes. The careless errors. SV40, which was later found in cancer tumors — that was what I would call a structural problem. It was an accepted part of the manufacturing process. If you use monkey kidneys, you open the door to germs which you don’t know are in those kidneys.

Q: Okay, but let’s ignore that distinction between different types of contaminants for a moment. What contaminants did you find in your many years of work with vaccines?

A: All right. I’ll give you some of what I came across, and I’ll also give you what colleagues of mine found. Here’s a partial list. In the Rimavex measles vaccine, we found various chicken viruses. In polio vaccine, we found acanthamoeba, which is a so-called “brain-eating” amoeba. Simian cytomegalovirus in polio vaccine. Simian foamy virus in the rotavirus vaccine. Bird-cancer viruses in the MMR vaccine. Various micro-organisms in the anthrax vaccine. I’ve found potentially dangerous enzyme inhibitors in several vaccines. Duck, dog, and rabbit viruses in the rubella vaccine. Avian leucosis virus in the flu vaccine. Pestivirus in the MMR vaccine.

Q: Let me get this straight. These are all contaminants which don’t belong in the vaccines.

A: That’s right. And if you try to calculate what damage these contaminants can cause, well, we don’t really know, because no testing has been done, or very little testing. It’s a game of roulette. You take your chances. Also, most people don’t know that some polio vaccines, adenovirus vaccines, rubella and hep A and measles vaccines have been made with aborted human fetal tissue. I have found what I believed were bacterial fragments and poliovirus in these vaccines from time to time — which may have come from that fetal tissue. When you look for contaminants in vaccines, you can come up with material that IS puzzling. You know it shouldn’t be there, but you don’t know exactly what you’ve got. I have found what I believed was a very small “fragment” of human hair and also human mucus. I have found what can only be called “foreign protein,” which could mean almost anything. It could mean protein from viruses.

Q: Alarm bells are ringing all over the place.

A: How do you think I felt? Remember, this material is going into the bloodstream without passing through some of the ordinary immune defenses.

Q: How were your findings received?

A: Basically, it was, don’t worry, this can’t be helped. In making vaccines, you use various animals’ tissue, and that’s where this kind of contamination enters in. Of course, I’m not even mentioning the standard chemicals like formaldehyde, mercury, and aluminum which are purposely put into vaccines.

Q: This information is pretty staggering.

A: Yes. And I’m just mentioning some of the biological contaminants. Who knows how many others there are? Others we don’t find because we don’t think to look for them. If tissue from, say, a bird is used to make a vaccine, how many possible germs can be in that tissue? We have no idea. We have no idea what they might be, or what effects they could have on humans.

Q: And beyond the purity issue?

A: You are dealing with the basic faulty premise about vaccines. That they intricately stimulate the immune system to create the conditions for immunity from disease. That is the bad premise. It doesn’t work that way. A vaccine is supposed to “create” antibodies which, indirectly, offer protection against disease. However, the immune system is much larger and more involved than antibodies and their related “killer cells.”

Q: The immune system is?

A: The entire body, really. Plus the mind. It’s all immune system, you might say. That is why you can have, in the middle of an epidemic, those individuals who remain healthy.

Q: So the level of general health is important.

A: More than important. Vital.

Q: How are vaccine statistics falsely presented?

A: There are many ways. For example, suppose that 25 people who have received the hepatitis B vaccine come down with hepatitis. Well, hep B is a liver disease. But you can call liver disease many things. You can change the diagnosis. Then, you’ve concealed the root cause of the problem.

Q: And that happens?

A: All the time. It HAS to happen, if the doctors automatically assume that people who get vaccines DO NOT come down with the diseases they are now supposed to be protected from. And that is exactly what doctors assume.You see, it’s circular reasoning. It’s a closed system. It admits no fault. No possible fault. If a person who gets a vaccine against hepatitis gets hepatitis, or gets some other disease, the automatic assumption is, this had nothing to do with the disease.

Q: In your years working in the vaccine establishment, how many doctors did you encounter who admitted that vaccines were a problem?

A: None. There were a few who privately questioned what they were doing. But they would never go public, even within their companies.

Q: What was the turning point for you?

A: I had a friend whose baby died after a DPT shot.

Q: Did you investigate?

A: Yes, informally. I found that this baby was completely healthy before the vaccination. There was no reason for his death, except the vaccine. That started my doubts. Of course, I wanted to believe that the baby had gotten a bad shot from a bad lot. But as I looked into this further, I found that was not the case in this instance. I was being drawn into a spiral of doubt that increased over time. I continued to investigate.I found that, contrary to what I thought, vaccines are not tested in a scientific way.

Q: What do you mean?

A: For example, no long-term studies are done on any vaccines. Long-term follow-up is not done in any careful way. Why? Because, again, the assumption is made that vaccines do not cause problems. So why should anyone check? On top of that, a vaccine reaction is defined so that all bad reactions are said to occur very soon after the shot is given. But that does not make sense.

Q: Why doesn’t it make sense?

A: Because the vaccine obviously acts in the body for a long period of time after it is given. A reaction can be gradual. Deterioration can be gradual. Neurological problems can develop over time. They do in various conditions, even according to a conventional analysis. So why couldn’t that be the case with vaccines? If chemical poisoning can occur gradually, why couldn’t that be the case with a vaccine which contains mercury?

Q: And that is what you found?

A: Yes. You are dealing with correlations, most of the time. Correlations are not perfect. But if you get 500 parents whose children have suffered neurological damage during a one-year period after having a vaccine, this should be sufficient to spark off an intense investigation.

Q: Has it been enough?

A: No. Never. This tells you something right away.

Q: Which is?

A: The people doing the investigation are not really interested in looking at the facts. They assume that the vaccines are safe. So, when they do investigate, they invariably come up with exonerations of the vaccines. They say, “This vaccine is safe.” But what do they base those judgments on? They base them on definitions and ideas which automatically rule out a condemnation of the vaccine.

Q: There are numerous cases where a vaccine campaign has failed. Where people have come down with the disease against which they were vaccinated.

A: Yes, there are many such instances. And there the evidence is simply ignored. It’s discounted. The experts say, if they say anything at all, that this is just an isolated situation, but overall the vaccine has been shown to be safe. But if you add up all the vaccine campaigns where damage and disease have occurred, you realize that these are NOT isolated situations.

Q: Did you ever discuss what we are talking about here with colleagues, when you were still working in the vaccine establishment?

A: Yes I did.

Q: What happened?

A: Several times I was told to keep quiet. It was made clear that I should go back to work and forget my misgivings. On a few occasions, I encountered fear. Colleagues tried to avoid me. They felt they could be labeled with “guilt by association.” All in all, though, I behaved myself. I made sure I didn’t create problems for myself.

Q: If vaccines actually do harm, why are they given?

A: First of all, there is no “if.” They do harm. It becomes a more difficult question to decide whether they do harm in those people who seem to show no harm. Then you are dealing with the kind of research which should be done, but isn’t. Researchers should be probing to discover a kind of map, or flow chart, which shows exactly what vaccines do in the body from the moment they enter. This research has not been done. As to why they are given, we could sit here for two days and discuss all the reasons. As you’ve said many times, at different layers of the system people have their motives. Money, fear of losing a job, the desire to win brownie points, prestige, awards, promotion, misguided idealism, unthinking habit, and so on. But, at the highest levels of the medical cartel, vaccines are a top priority because they cause a weakening of the immune system. I know that may be hard to accept, but it’s true. The medical cartel, at the highest level, is not out to help people, it is out to harm them, to weaken them. To kill them. At one point in my career, I had a long conversation with a man who occupied a high government position in an African nation. He told me that he was well aware of this. He told me that WHO is a front for these depopulation interests. There is an underground, shall we say, in Africa, made up of various officials who are earnestly trying to change the lot of the poor. This network of people knows what is going on. They know that vaccines have been used, and are being used, to destroy their countries, to make them ripe for takeover by globalist powers. I have had the opportunity to speak with several of these people from this network.

Q: Is Thabo Mbeki, the president of South Africa, aware of the situation?

A: I would say he is partially aware. Perhaps he is not utterly convinced, but he is on the way to realizing the whole truth. He already knows that HIV is a hoax. He knows that the AIDS drugs are poisons which destroy the immune system. He also knows that if he speaks out, in any way, about the vaccine issue, he will be branded a lunatic. He has enough trouble after his stand on the AIDS issue.

Q: This network you speak of.

A: It has accumulated a huge amount of information about vaccines. The question is, how is a successful strategy going to be mounted? For these people, that is a difficult issue.

Q: And in the industrialized nations?

A: The medical cartel has a stranglehold, but it is diminishing. Mainly because people have the freedom to question medicines. However, if the choice issue [the right to take or reject any medicine] does not gather steam, these coming mandates about vaccines against biowarefare germs are going to win out. This is an important time.

Q: The furor over the hepatits B vaccine seems one good avenue.

A: I think so, yes. To say that babies must have the vaccine-and then in the next breath, admitting that a person gets hep B from sexual contacts and shared needles — is a ridiculous juxtaposition. Medical authorities try to cover themselves by saying that 20,000 or so children in the US get hep B every year from “unknown causes,” and that’s why every baby must have the vaccine. I dispute that 20,00 figure and the so-called studies that back it up.

Q: Andrew Wakefield, the British MD who uncovered the link between the MMR vaccine and autism, has just been fired from his job in a London hospital.

A: Yes. Wakefield performed a great service. His correlations between the vaccine and autism are stunning. Perhaps you know that Tony Blair’s wife is involved with alternative health. There is the possibility that their child has not been given the MMR. Blair recently side-stepped the question in press interviews, and made it seem that he was simply objecting to invasive questioning of his “personal and family life.” In any event, I believe his wife has been muzzled. I think, if given the chance, she would at least say she is sympathetic to all the families who have come forward and stated that their children were severely damaged by the MMR.

Q: British reporters should try to get through to her.

A: They have been trying. But I think she has made a deal with her husband to keep quiet, no matter what. She could do a great deal of good if she breaks her promise. I have been told she is under pressure, and not just from her husband. At the level she occupies, MI6 and British health authorities get into the act. It is thought of as a matter of national security.

Q: Well, it is national security, once you understand the medical cartel.

A: It is global security. The cartel operates in every nation. It zealously guards the sanctity of vaccines. Questioning these vaccines is on the same level as a Vatican bishop questioning the sanctity of the sacrament of the Eucharist in the Catholic Church.

Q: I know that a Hollywood celebrity stating publicly that he will not take a vaccine is committing career suicide.

A: Hollywood is linked very powerfully to the medical cartel. There are several reasons, but one of them is simply that an actor who is famous can draw a huge amount of publicity if he says ANYTHING. In 1992, I was present at your demonstration against the FDA in downtown Los Angeles. One or two actors spoke against the FDA. Since that time, you would be hard pressed to find an actor who has spoken out in any way against the medical cartel.

Q: Within the National Institutes of Health, what is the mood, what is the basic frame of mind?

A: People are competing for research monies. The last thing they think about is challenging the status quo. They are already in an intramural war for that money. They don’t need more trouble. This is a very insulated system. It depends on the idea that, by and large, modern medicine is very successful on every frontier. To admit systemic problems in any area is to cast doubt on the whole enterprise. You might therefore think that NIH is the last place one should think about holding demonstrations. But just the reverse is true. If five thousand people showed up there demanding an accounting of the actual benefits of that research system, demanding to know what real health benefits have been conferred on the public from the billions of wasted dollars funneled to that facility, something might start. A spark might go off. You might get, with further demonstrations, all sorts of fall-out. Researchers — a few — might start leaking information.

Q: A good idea.

A: People in suits standing as close to the buildings as the police will allow. People in business suits, in jogging suits, mothers and babies. Well-off people. Poor people. All sorts of people.

Q: What about the combined destructive power of a number of vaccines given to babies these days?

A: It is a travesty and a crime. There are no real studies of any depth which have been done on that. Again, the assumption is made that vaccines are safe, and therefore any number of vaccines given together are safe as well. But the truth is, vaccines are not safe. Therefore the potential damage increases when you give many of them in a short time period.

Q: Then we have the fall flu season.

A: Yes. As if only in the autumn do these germs float in to the US from Asia. The public swallows that premise. If it happens in April, it is a bad cold. If it happens in October, it is the flu.

Q: Do you regret having worked all those years in the vaccine field?

A: Yes. But after this interview, I’ll regret it a little less. And I work in other ways. I give out information to certain people, when I think they will use it well.

Q: What is one thing you want the public to understand?

A: That the burden of proof in establishing the safety and efficacy of vaccines is on the people who manufacture and license them for public use. Just that. The burden of proof is not on you or me. And for proof you need well-designed long-term studies. You need extensive follow-up. You need to interview mothers and pay attention to what mothers say about their babies and what happens to them after vaccination. You need all these things. The things that are not there.

Q: The things that are not there.

A: Yes.

Q: To avoid any confusion, I’d like you to review, once more, the disease problems that vaccines can cause. Which diseases, how that happens.

A: We are basically talking about two potential harmful outcomes. One, the person gets the disease from the vaccine. He gets the disease which the vaccine is supposed to protect him from. Because, some version of the disease is in the vaccine to begin with. Or two, he doesn’t get THAT disease, but at some later time, maybe right away, maybe not, he develops another condition which is caused by the vaccine. That condition could be autism, what’s called autism, or it could be some other disease like meningitis. He could become mentally disabled.

Q: Is there any way to compare the relative frequency of these different outcomes?

A: No. Because the follow-up is poor. We can only guess. If you ask, out of a population of a hundred thousand children who get a measles vaccine, how many get the measles, and how many develop other problems from the vaccine, there is a no reliable answer. That is what I’m saying. Vaccines are superstitions. And with superstitions, you don’t get facts you can use. You only get stories, most of which are designed to enforce the superstition. But, from many vaccine campaigns, we can piece together a narrative that does reveal some very disturbing things. People have been harmed. The harm is real, and it can be deep and it can mean death. The harm is NOT limited to a few cases, as we have been led to believe. In the US, there are groups of mothers who are testifying about autism and childhood vaccines. They are coming forward and standing up at meetings. They are essentially trying to fill in the gap that has been created by the researchers and doctors who turn their backs on the whole thing.

Q: Let me ask you this. If you took a child in, say, Boston and you raised that child with good nutritious food and he exercised every day and he was loved by his parents, and he didn’t get the measles vaccine, what would be his health status compared with the average child in Boston who eats poorly and watches five hours of TV a day and gets the measles vaccine?

A: Of course there are many factors involved, but I would bet on the better health status for the first child. If he gets measles, if he gets it when he is nine, the chances are it will be much lighter than the measles the second child might get. I would bet on the first child every time.

Q: How long did you work with vaccines?

A: A long time. Longer than ten years.

Q: Looking back now, can you recall any good reason to say that vaccines are successful?

A: No, I can’t. If I had a child now, the last thing I would allow is vaccination. I would move out of the state if I had to. I would change the family name. I would disappear. With my family. I’m not saying it would come to that. There are ways to sidestep the system with grace, if you know how to act. There are exemptions you can declare, in every state, based on religious and/or philosophic views. But if push came to shove, I would go on the move.

Q: And yet there are children everywhere who do get vaccines and appear to be healthy.

A: The operative word is “appear.” What about all the children who can’t focus on their studies? What about the children who have tantrums from time to time? What about the children who are not quite in possession of all their mental faculties? I know there are many causes for these things, but vaccines are one cause. I would not take the chance. I see no reason to take the chance. And frankly, I see no reason to allow the government to have the last word. Government medicine is, from my experience, often a contradiction in terms. You get one or the other, but not both.

Q: So we come to the level playing field.

A: Yes. Allow those who want the vaccines to take them. Allow the dissidents to decline to take them. But, as I said earlier, there is no level playing field if the field is strewn with lies. And when babies are involved, you have parents making all the decisions. Those parents need a heavy dose of truth. What about the child I spoke of who died from the DPT shot? What information did his parents act on? I can tell you it was heavily weighted. It was not real information.

Q: Medical PR people, in concert with the press, scare the hell out of parents with dire scenarios about what will happen if their kids don’t get shots.

A: They make it seem a crime to refuse the vaccine. They equate it with bad parenting. You fight that with better information. It is always a challenge to buck the authorities. And only you can decide whether to do it. It is every person’s responsibility to make up his mind. The medical cartel likes that bet. It is betting that the fear will win.

Dr. Mark Randall is the pseudonym of a vaccine researcher who worked for many years in the labs of major pharmaceutical houses and the US government’s National Institutes of Health.

Mark retired during the last decade. He says he was “disgusted with what he discovered about vaccines.”

_________________________________________________


http://vactruth.com/2012/03/21/vaccination-campaign-exposed/

Exposed Lie #1

‘Be a Hero!’

Giving your child vaccinations does not automatically qualify you as a hero. We all want to be a hero in our children’s eyes. I believe this can only be achieved by giving them love, care and keeping them safe.

The only people that will think that you are a hero for vaccinating your child are the pharmaceutical industries who manufacture the vaccines and the governments who sanction them.

To state that by giving children vaccinations automatically makes parents into instant heroes, is propaganda and a marketing ploy intended to force parents into taking up the recommended vaccination schedule.

Tesla_WTC_Solution
24th September 2014, 19:00
Another PA user posted a good thing for all of us to read today:


Quote Posted by HugoJudd (here)

"Many thanks to TY Bollinger (On Caravan to Midnight) who put it into lay mans terms. I know this has probably been done to death but there appears to be some new material. Basically he said that TESTOSTERONE in the body bonds with MERCURY and prevents it from being washed out. So if a child has abnormal Testosterone levels, the Mercury in a vaccine will linger and poison the child. They are beginning to uncover a link between autism and elevated testosterone!"

http://www.ageofautism.com/2008/04/mercury-testost.html

:usa2::usa2::usa2: THANK YOU HUGO JUDD :usa2::usa2::usa2:

Tesla_WTC_Solution
29th September 2014, 21:06
this is really creepy:

http://www.cnn.com/2014/09/29/health/colorado-paralysis-enterovirus/index.html?hpt=hp_t2

CDC investigates kids' limb paralysis; is enterovirus to blame?
By Jacque Wilson, CNN
updated 2:49 PM EDT, Mon September 29, 2014
Most of the children experienced a respiratory illness before being admitted to the hospital.
Most of the children experienced a respiratory illness before being admitted to the hospital.
STORY HIGHLIGHTS

Nine children in Colorado hospitalized with limb paralysis
MRI tests spotted abnormalities in their spinal gray matter
Health officials are looking for the cause; it may be enterovirus

(CNN) -- Health officials are looking for the cause of a neurologic illness that's affected nine children in Colorado.

The children were hospitalized with muscle weakness in their limbs between August 9 and September 17, according to the Centers for Disease Control and Prevention; MRI tests spotted abnormalities in the children's spinal gray matter. Most of the children experienced a respiratory illness before being admitted to the hospital.

The CDC is still investigating the cause of these symptoms. Health officials do not believe that the cases were caused by polio, as eight of the nine children are up to date on their polio vaccinations.

"We don't know, at this point, if there is any association between the enterovirus EV-D68 that's circulating and the paralytic conditions some of the children in Colorado are experiencing," CDC spokesman Tom Skinner said.

Tests of the children's cerebrospinal fluid came back negative for enteroviruses and West Nile virus. But a test of their nasal passages found enterovirus in six out of eight patients who were tested.

Of those six, four tested positive for enterovirus D68, which has been sending children across North America to the hospital with severe respiratory illnesses. The other two test results are pending.

"It could be something else. That doesn't prove cause and effect, but it's circumstantial evidence," said Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases. The cause "still remains a puzzle."
Virus sends hundreds to hospital

Enterovirus: My son was 'like a goldfish gasping for breath'

A cluster of children with similar paralysis symptoms was identified in California last year. Samples from two of the children tested positive for enterovirus D68.

Enterovirus D68 is part of the Picornaviridae family, which also includes the poliovirus, other enteroviruses and rhinoviruses. Enteroviruses are very common, especially in late summer and early fall. The CDC estimates that 10 million to 15 million infections occur in the United States each year.

These viruses usually appear like the common cold; symptoms include sneezing, a runny nose and a cough. Most people recover without any treatment. But some types of enterovirus are more serious. These can cause hand, foot and mouth disease; viral meningitis; encephalitis (inflammation of the brain); an infection of the heart; and paralysis in some patients.

This year, enterovirus D68 seems to be exacerbating breathing problems in children who have asthma. The virus has infected at least 277 people in 40 states, according to the CDC. Cases have also been reported in Canada.

CNN affiliate WCBS reported Friday that a New Jersey toddler died last week from a severe respiratory illness and that the CDC will be testing samples to see whether he had enterovirus D68.

The CDC is asking other hospitals across the country to be on the lookout for similar cases and to send in information on any patients with these symptoms.

______________________________________


they're blaming a common cold for this happening in kids recently polio vaccinated.
as lots of people know, bacteria and viruses can donate DNA to other bacteria and viruses.

so no one's being honest about how this happened or what the mechanism really was.

for example, the enterovirus could have interacted with the polio vaccine to create a completely novel organism capable of causing paralysis along with flulike symptoms.

food for very grave though, sadly.

Swan
1st November 2014, 11:05
http://www.iflscience.com/health-and-medicine/chemical-extracted-broccoli-sprouts-may-help-ease-autism-symptoms


A new study found that a chemical in broccoli sprouts is able to temporarily improve symptoms of Autism Spectrum Disorder (ASD). The research was a collaboration between researchers at Johns Hopkins University School of Medicine in Baltimore and Massachusetts General Hospital for Children and it was published in the Proceedings of the National Academy of Sciences.

Those with ASD generally have higher than normal levels of oxidative stress within their cells, and previous research has shown that about half experience an improvement of behavioral symptoms when experiencing a fever. This effect is only temporary, as the symptoms return after the fever subsides. Andrew Zimmerman and his team at Mass. General were not sure why this happened, and set out to discover the mechanism. The current study used sulforaphane, a chemical extracted from broccoli sprouts.

Broccoli sprouts, along with other cruciferous veggies, contain precursors of a chemical called sulforaphane. This molecule has been studied for its ability to help combat oxidative stress in cells. Cells that have been damaged by this stress can display abnormalities in cell signaling, and can even develop inflammation leading to chronic diseases like cancer. Previous research by co-author Paul Talalay of Johns Hopkins found that sulforaphane helps the body’s heat-shock response, which protects cells when faced with fevers or other sources high temperatures.

Talalay and Zimmerman paired up in the current study to see if sulforaphane could replicate the ASD symptom-abating effects of a fever. The study used 40 male patients with severe or moderate ASD, ranging in age from 13 to 27. Weight-dependent dosages between 9-27 milligrams were given to 26 of the participants every day for 18 weeks. The remaining 14 were given placebos.

Three different assessments were used to rate behavior before the study and after weeks 4, 10, and 18. Additionally, many of the study participants were also assessed again several weeks after the end of the treatment. Ultimately, the researchers found that about half of those receiving the treatment saw improvement.

"We believe that this may be preliminary evidence for the first treatment for autism that improves symptoms by apparently correcting some of the underlying cellular problems," Talalay said in a press release.

Improvements with social interactions had been recorded in 46% of the participants that had taken sulforaphane. Some of these participants had also begun to look people in the eye and shake hands; a first for all of them. A total of 54% of participants exhibited an improvement with aberrant behaviors—including ritualistic movements and hyperactivity. Verbal communication improved among 42% of them. However, weeks after they stopped taking the sulforaphane, the symptoms returned to their pre-study levels.

"We are far from being able to declare a victory over autism, but this gives us important insights into what might help," Zimmerman added.

Tesla_WTC_Solution
3rd November 2014, 04:29
Thank you Swan for posting this info about "sulforaphane"

Weird that a few minutes before checking this thread for updates, was thinking again about "heparan sulfate" and its link to autism.

Thank you for this!

Tesla_WTC_Solution
6th November 2014, 00:50
Hello PA, I have not updated this thread with info re: its original assertions!!

but there are some important papers out:

http://www.news-medical.net/news/20140822/Children-and-adolescents-with-autism-have-surplus-of-synapses-in-brain.aspx

Children and adolescents with autism have surplus of synapses in brain
Published on August 22, 2014 at 2:00 AM


Children and adolescents with autism have a surplus of synapses in the brain, and this excess is due to a slowdown in a normal brain "pruning" process during development, according to a study by neuroscientists at Columbia University Medical Center (CUMC). Because synapses are the points where neurons connect and communicate with each other, the excessive synapses may have profound effects on how the brain functions. The study was published in the August 21 online issue of the journal Neuron.

A drug that restores normal synaptic pruning can improve autistic-like behaviors in mice, the researchers found, even when the drug is given after the behaviors have appeared.

"This is an important finding that could lead to a novel and much-needed therapeutic strategy for autism," said Jeffrey Lieberman, MD, Lawrence C. Kolb Professor and Chair of Psychiatry at CUMC and director of New York State Psychiatric Institute, who was not involved in the study.

Although the drug, rapamycin, has side effects that may preclude its use in people with autism, "the fact that we can see changes in behavior suggests that autism may still be treatable after a child is diagnosed, if we can find a better drug," said the study's senior investigator, David Sulzer, PhD, professor of neurobiology in the Departments of Psychiatry, Neurology, and Pharmacology at CUMC.

During normal brain development, a burst of synapse formation occurs in infancy, particularly in the cortex, a region involved in autistic behaviors; pruning eliminates about half of these cortical synapses by late adolescence. Synapses are known to be affected by many genes linked to autism, and some researchers have hypothesized that people with autism may have more synapses.

To test this hypothesis, co-author Guomei Tang, PhD, assistant professor of neurology at CUMC, examined brains from children with autism who had died from other causes. Thirteen brains came from children ages two to 9, and thirteen brains came from children ages 13 to 20. Twenty-two brains from children without autism were also examined for comparison.

Dr. Tang measured synapse density in a small section of tissue in each brain by counting the number of tiny spines that branch from these cortical neurons; each spine connects with another neuron via a synapse.

By late childhood, she found, spine density had dropped by about half in the control brains, but by only 16 percent in the brains from autism patients.

"It's the first time that anyone has looked for, and seen, a lack of pruning during development of children with autism," Dr. Sulzer said, "although lower numbers of synapses in some brain areas have been detected in brains from older patients and in mice with autistic-like behaviors."

Clues to what caused the pruning defect were also found in the patients' brains; the autistic children's brain cells were filled with old and damaged parts and were very deficient in a degradation pathway known as "autophagy." Cells use autophagy (a term from the Greek for self-eating) to degrade their own components.

Using mouse models of autism, the researchers traced the pruning defect to a protein called mTOR. When mTOR is overactive, they found, brain cells lose much of their "self-eating" ability. And without this ability, the brains of the mice were pruned poorly and contained excess synapses. "While people usually think of learning as requiring formation of new synapses, "Dr. Sulzer says, "the removal of inappropriate synapses may be just as important."

The researchers could restore normal autophagy and synaptic pruning-and reverse autistic-like behaviors in the mice-by administering rapamycin, a drug that inhibits mTOR. The drug was effective even when administered to the mice after they developed the behaviors, suggesting that such an approach may be used to treat patients even after the disorder has been diagnosed.

Because large amounts of overactive mTOR were also found in almost all of the brains of the autism patients, the same processes may occur in children with autism.

"What's remarkable about the findings," said Dr. Sulzer, "is that hundreds of genes have been linked to autism, but almost all of our human subjects had overactive mTOR and decreased autophagy, and all appear to have a lack of normal synaptic pruning. This says that many, perhaps the majority, of genes may converge onto this mTOR/autophagy pathway, the same way that many tributaries all lead into the Mississippi River. Overactive mTOR and reduced autophagy, by blocking normal synaptic pruning that may underlie learning appropriate behavior, may be a unifying feature of autism."

Alan Packer, PhD, senior scientist at the Simons Foundation, which funded the research, said the study is an important step forward in understanding what's happening in the brains of people with autism.

"The current view is that autism is heterogeneous, with potentially hundreds of genes that can contribute. That's a very wide spectrum, so the goal now is to understand how those hundreds of genes cluster together into a smaller number of pathways; that will give us better clues to potential treatments," he said.

"The mTOR pathway certainly looks like one of these pathways. It is possible that screening for mTOR and autophagic activity will provide a means to diagnose some features of autism, and normalizing these pathways might help to treat synaptic dysfunction and treat the disease."
Source:

Columbia University Medical Center




also

http://www.sciencedaily.com/releases/2014/10/141010154926.htm


Neural stem cell overgrowth, autism-like behavior linked, mice study suggests

Date:
October 10, 2014

Source:
University of California, Los Angeles (UCLA), Health

Summary:
A new study shows how, in pregnant mice, inflammation, a first line defense of the immune system, can trigger an excessive division of neural stem cells that can cause “overgrowth” in the offspring’s brain, and, ultimately, autistic behavior.

People with autism spectrum disorder often experience a period of accelerated brain growth after birth. No one knows why, or whether the change is linked to any specific behavioral changes.
Related Articles

Stem cell
Adult stem cell
Neuroscience
Embryonic stem cell
Neurobiology
T cell

A new study by UCLA researchers demonstrates how, in pregnant mice, inflammation, a first line defense of the immune system, can trigger an excessive division of neural stem cells that can cause "overgrowth" in the offspring's brain.

The paper appears Oct. 9 in the online edition of the journal Stem Cell Reports.

"We have now shown that one way maternal inflammation could result in larger brains and, ultimately, autistic behavior, is through the activation of the neural stem cells that reside in the brain of all developing and adult mammals," said Dr. Harley Kornblum, the paper's senior author and a director of the Neural Stem Cell Research Center at UCLA's Semel Institute for Neuroscience and Human Behavior.

In the study, the researchers mimicked environmental factors that could activate the immune system -- such as an infection or an autoimmune disorder -- by injecting a pregnant mouse with a very low dose of lipopolysaccharide, a toxin found in E. coli bacteria. The researchers discovered the toxin caused an excessive production of neural stem cells and enlarged the offspring's' brains.

Neural stem cells become the major types of cells in the brain, including the neurons that process and transmit information and the glial cells that support and protect them.

Notably, the researchers found that mice with enlarged brains also displayed behaviors like those associated with autism in humans. For example, they were less likely to vocalize when they were separated from their mother as pups, were less likely to show interest in interacting with other mice, showed increased levels of anxiety and were more likely to engage in repetitive behaviors like excessive grooming.

Kornblum, who also is a professor of psychiatry, pharmacology and pediatrics at the David Geffen School of Medicine at UCLA, said there are many environmental factors that can activate a pregnant woman's immune system.

"Although it's known that maternal inflammation is a risk factor for some neurodevelopmental disorders such as autism, it's not thought to directly cause them," he said. He noted that autism is clearly a highly heritable disorder, but other, non-genetic factors clearly play a role.

The researchers also found evidence that the brain growth triggered by the immune reaction was even greater in mice with a specific genetic mutation -- a lack of one copy of a tumor suppressor gene called phosphatase and tensin homolog, or PTEN. The PTEN protein normally helps prevent cells from growing and dividing too rapidly. In humans, having an abnormal version of the PTEN gene leads to very large head size or macrocephaly, a condition that also is associated with a high risk for autism.

"Autism is a complex group of disorders, with a variety of causes," Kornblum said. "Our study shows a potential way that maternal inflammation could be one of those contributing factors, even if it is not solely responsible, through interactions with known risk factors."

In addition, the team found that the proliferation of neural stem cell and brain overgrowth was stimulated by the activation of a specific molecular pathway. (A pathway is a series of actions among molecules within a cell that leads to a certain cell function.) This pathway involved the enzyme NADPH oxidase, which the UCLA researchers have previously found to be associated with neural stem cell growth.

"The discovery of these mechanisms has identified new therapeutic targets for common autism-associated risk factors," said Janel Le Belle, an associate researcher in Kornblum's lab and the paper's lead author. "The molecular pathways that are involved in these processes are ones that can be manipulated and possibly even reversed pharmacologically.

"In agreement with past clinical findings, these data add to the significant evidence that autism-associated brain alterations begin prenatally and continue to evolve after birth," she said.

Kornblum added that the findings that neural stem cell hyper-proliferation can contribute to autism-associated features may be somewhat surprising. "Autism neuropathology is primarily thought of as a dysregulation of neuronal connectivity, although the molecular and cellular means by which this occurs is not known," he said. "Therefore, our hypothesis -- that one potential means by which autism may develop is through an overproduction of cells in the brain, which then results in altered connectivity -- is a new way of thinking about autism etiology."

The next step, the researchers say, is to determine if and how the changes they observed lead to changes in the connections between brain cells, and if those effects can be altered after they have happened.

Story Source:

The above story is based on materials provided by University of California, Los Angeles (UCLA), Health Sciences. The original article was written by Mark Wheeler. Note: Materials may be edited for content and length.

Journal Reference:

Janel E. Le Belle, Jantzen Sperry, Amy Ngo, Yasmin Ghochani, Dan R. Laks, Manuel López-Aranda, Alcino J. Silva, Harley I. Kornblum. Maternal Inflammation Contributes to Brain Overgrowth and Autism-Associated Behaviors through Altered Redox Signaling in Stem and Progenitor Cells. Stem Cell Reports, 2014; DOI: 10.1016/j.stemcr.2014.09.004

Cite This Page:

MLA
APA
Chicago

University of California, Los Angeles (UCLA), Health Sciences. "Neural stem cell overgrowth, autism-like behavior linked, mice study suggests." ScienceDaily. ScienceDaily, 10 October 2014. <www.sciencedaily.com/releases/2014/10/141010154926.htm>.




:yuck: :confused:



the universities researched the molecular pathway in question and found a way to diagnose and possibly treat autism :(

:der:

Tesla_WTC_Solution
6th November 2014, 20:43
Heyyyyy, UCLA had a PhD interested in this in 2011, maybe it didn't get lifted from PA :jaw:

https://iacc.hhs.gov/events/2011/slides_geri_dawson_041111.pdf


Translational Medicine Research in Autism:
Challenges and Opportunities
January 25
-
27, 2011
Santa Monica, CA



Mustafa Sahin,MD, PhD Harvard - Tuberous sclerosis complex

Alcino Silva, PhD UCLA - mTOR signaling in autism and other psychiatric disorders

Mark Bear, PhD MIT - Insights from fragile X and related single gene disorders

Huda Zoghbi, MD Baylor Rett - syndrome and MECP2 Duplication Disorder: Relevance
to ASD
Randy Carpenter, MD
Seaside
Discussion leader




now we have to wait and see which cause is most profitable to the drug companies :(



http://snnla.org/snn-helps-ucla-recruit-families-for-autism-genetic-cause-research/


Last year this time, Dr. Daniel Geschwind, a renowned autism scientist and researcher at UCLA, joined Special Needs Network (SNN) president Areva Martin, Esq., to announce a National Institutes of Health (NIH) $15 million grant project at UCLA. The research project is focused on helping to determine the genetic causes of autism in African American children – a population that has been overlooked by autism researchers.



The five year research project is now at the stage where children and families are needed to actively participate in the study. Special Needs Network has been working closely with Dr. Geschwind and his staff at UCLA since the project inception and is currently helping to identify families with autistic children. After months of community outreach and engagement of African American families in the Los Angeles area, SNN and UCLA will host their first screening day on Saturday, July 19 at St. Bernadette elementary school in the Crenshaw District of LA. St. Bernadette is one of SNN’s community partners and serves as the site for its famed summer autism camp program, Camp JPAC.



Recruitment for participants is coming at a time when autism is on the rise. A recent announcement from the Centers for Disease Control (CDC) identified that our nation is facing an epidemic when it comes to autism spectrum disorder (ASD) and our children. The CDC report, released in March, states that diagnoses of autism have increased 30 percent since 2008. ASDs are complex developmental disorders that affect how a person behaves, interacts with others, communicates and learns. There is no known cause or cure.


however UCLA has a good research reputation and I hope that the NIH has not misplaced its trust.

we need answers because although a preventive cure is in sight, there may be no cure for those who have already developed autism spectrum disorder.

we aren't going to enjoy the treatments people come up with for this. :sick:

without luck.

Tesla_WTC_Solution
6th November 2014, 20:48
People are going to need an MTOR or glutamate blocker in order to treat ongoing ASD.

medical marijuana is one of the back door ways to accomplishing this.

if you can't remove the extra receptors or keep the immune system from hating them,
the least you can do is close some of the doors.

sheme
6th November 2014, 22:33
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063799

http://scholar.google.co.uk/scholar?q=rapamycin+in+the+treatment+of+autism&hl=en&as_sdt=0&as_vis=1&oi=scholart&sa=X&ei=f_hbVJzYLcPYaqu5gNgD&ved=0CEEQgQMwAA


Tesla please clear some space in your PM box. good night.:o

21g
9th November 2014, 04:19
Hi Tes`

This is intuitive and speculative info but i feel should share in case it might be useful.

Autism/ ADHD was strongly in the public consciousness during the early noughties, presumably because of
a big increase in cases aswell as diagnoses.

Late noughties ( 2007 - present ) their has been a notable public interest in the plight of the honeybee.

In both cases, subjectively speaking, it has evoked a visceral response in people. Dont mean to sound cold hearted
( i have a vested personal interest in both issues ) but you cant help but wonder why ? As in, why this, why now ?

Anyhow, modern pesticides ( neonicotinoids ) were introduced in the 80`s i think, ( DONT QUOTE ME ON THAT ! ) but essentially,
their usage has increased dramatically since then. I believe the dramatic increase in Autism / ADHD might be related in some way ?

We will have been ingesting these pesticides in ever increasing amounts since that time. As regards the honeybee, it messes up their gut,
leaving their immune system compromised.

So, the honeybee,the canary in the coalmine, could be flagging up what we are doing to the natural world, which includes us, and how we are
doing it. Using persistent, neurotoxic chemicals that also damage the gut. The synergistic effects of a Neonicitinoid plus, say a vaccine for example,
has to impact us. Does it mess up our gut aswell ? I know the gut is implicated in Autism / ADHD, so maybe their is a link in some way ?

Apologies if this a bit meandering, but i think you get the gist.
What do you think ?

G

Agape
2nd December 2014, 15:55
You may enjoy reading this ( but they have an audio version of the book as well ) :

The boy whose brain could unlock autism : https://medium.com/matter-archive/the-boy-whose-brain-could-unlock-autism-70c3d64ff221

From Henry Makram , leading scientists on the European Human Brain Project research and father of boy diagnosed with ASD .

Their 'intense brain theory' is very sound& sentient in my opinion ..

:angel:




I'd also suggest moving this thread to "Alternative Science&Medicine'' board and sticking it UP because it takes too long to find ..

Tesla_WTC_Solution
2nd December 2014, 19:48
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010743/



Front Hum Neurosci. 2010; 4: 224.
Published online Dec 21, 2010. Prepublished online Aug 16, 2010. doi: 10.3389/fnhum.2010.00224
PMCID: PMC3010743
The Intense World Theory – A Unifying Theory of the Neurobiology of Autism

Kamila Markram1,* and Henry Markram1
Author information ► Article notes ► Copyright and License information ►
This article has been cited by other articles in PMC.
Go to:
Abstract

Autism covers a wide spectrum of disorders for which there are many views, hypotheses and theories. Here we propose a unifying theory of autism, the Intense World Theory. The proposed neuropathology is hyper-functioning of local neural microcircuits, best characterized by hyper-reactivity and hyper-plasticity.

Such hyper-functional microcircuits are speculated to become autonomous and memory trapped leading to the core cognitive consequences of hyper-perception, hyper-attention, hyper-memory and hyper-emotionality.

The theory is centered on the neocortex and the amygdala, but could potentially be applied to all brain regions.

The severity on each axis depends on the severity of the molecular syndrome expressed in different brain regions, which could uniquely shape the repertoire of symptoms of an autistic child.

The progression of the disorder is proposed to be driven by overly strong reactions to experiences that drive the brain to a hyper-preference and overly selective state, which becomes more extreme with each new experience and may be particularly accelerated by emotionally charged experiences and trauma.

This may lead to obsessively detailed information processing of fragments of the world and an involuntarily and systematic decoupling of the autist from what becomes a painfully intense world. The autistic is proposed to become trapped in a limited, but highly secure internal world with minimal extremes and surprises.

We present the key studies that support this theory of autism, show how this theory can better explain past findings, and how it could resolve apparently conflicting data and interpretations. The theory also makes further predictions from the molecular to the behavioral levels, provides a treatment strategy and presents its own falsifying hypothesis.

Keywords: autism, neocortex, amygdala, neural circuitry, connectivity, plasticity, NMDA, glutamate, perception, attention, memory, emotion, valproic acid, animal model

http://3.bp.blogspot.com/-Nx6QhFLMZiY/UVwZfu0Y0AI/AAAAAAAAAcM/cI30gTBf09c/s1600/superman2.jpg

Tesla_WTC_Solution
8th December 2014, 18:29
Ladies and gentlemen, another rather disturbing update re: so-called "environmental" factors (!) contributing to brain changes:

DMX-containing cough suppressant and cold medicines, possibly some tylenol products (?) and brain damage (Olney's Lesions)


http://en.wikipedia.org/wiki/Olney%27s_lesions

Olney's lesions, also known as NMDA receptor antagonist neurotoxicity (NAN), are a potential form of brain damage. They are named after John Olney, who conducted a study in 1989 to investigate neurotoxicity caused by PCP and related drugs.[1]

https://www.erowid.org/chemicals/dxm/faq/dxm_side_effects.shtml

https://drugs-forum.com/forum/showthread.php?t=17894

A layman's perspective after research:


Important Long-Term Dangers:

Psychological addiction and depression (from regular use)
Poisoning from Bromide Ions.
Irreversible brain damage (from chronic use at high doses)

Brain damage is fairly rare, occurring in less than 1% of the regular users that William White interviewed. He says, “They all used DXM very frequently. If you do DXM twice a month or less, you'll probably be OK. But remember there's always the risk of something going wrong.” FYI: William White is the ‘famous’ author of the DXM FAQ.


They give it to KIDS: (!!!!!)


http://www.mybwmc.org/library/41/000650

Acetaminophen, Dextromethorphan, and Pseudoephedrine
Pronunciation

(a seet a MIN oh fen, deks troe meth OR fan, & soo doe e FED rin)


U.S. Brand Names

Alka-Seltzer® Plus Flu Liqui-Gels® [OTC]; Comtrex® Non-Drowsy Cold and Cough Relief [OTC]; Contac® Severe Cold and Flu/Non-Drowsy [OTC]; Infants' Tylenol® Cold Plus Cough Concentrated Drops [OTC]; Sudafed® Severe Cold [OTC]; Thera-Flu® Severe Cold Non-Drowsy [OTC] [DSC]; Triaminic® Cough and Sore Throat Formula [OTC]; Tylenol® Cold Day Non-Drowsy [OTC]; Tylenol® Flu Non-Drowsy Maximum Strength [OTC]; Vicks® DayQuil® Multi-Symptom Cold and Flu [OTC]


"...Infants' Tylenol® Cold Plus Cough Concentrated Drops: Children 2-3 years (24-55 lb): 2 dropperfuls every 4-6 hours (maximum: 4 doses/24 hours)..."


Infants' Tylenol was recommended for everything from vaccination fevers to the common cold to teething pains.
With a child who already suffers liver problems due to heredity, it's a bit scary that doctors sacrifice that 1% who suffer the adverse reaction to DXM etc. in order to satisfy the herd.


Back to Olney's Lesions.

Evers, M.; Hollander, E. (2008). "Excitotoxicity in Autism". Autism. pp. 133–145. doi:10.1007/978-1-60327-489-0_6. ISBN 978-1-60327-488-3.




Tylenol products linked to autism epidemic:


http://www.autismcoach.com/tylenol-fueling-autism-epidemic/



Home
Article Database
Autism Scientific Research and News Articles
Tylenol Fueling Autism Epidemic?

Tylenol Fueling Autism Epidemic?

http://cdn3.bigcommerce.com/s-g6copot/product_images/uploaded_images/tylenol.jpg?t=1414073189

December 07, 2013. Tylenol, the supposedly safe alternative to aspirin for children, may be anything but. Researchers from the University of California, San Diego, found that among children who experienced an adverse reaction to the MMR vaccine (a vaccine which contains neurotoxic free glutamate), the children whose adverse vaccine reactions were treated with acetaminophen (Tylenol) were eight times more likely to develop an autism spectrum disorder than the children who were treated with ibuprofen (to see the pub med citation, click here).

I find it interesting to note that only a handful of children have suffered from Reyes Syndrome, but the FDA took stringent action to warn people not to use aspirin with their children, while FDA has not seen fit to take action to warn parents not to give their infants and young children Tylenol or to avoid it in pregnancy, and it is likely that huge numbers of children are being affected by it. (Note that Tylenol is not safe for anyone - it is the leading cause for calls to Poison Control Centers. In 2004, acetaminophen accounted for more than 56,000 emergency room visits, 2,600 hospitalizations and 458 deaths due to acute liver failure. Interestingly, the standard hospital protocol is to administer the supplement, N-Acetyl Cysteine, as an antidote. For a link to this paper, click here).

Tylenol depletes glutathione, the major free radical scavenger in the brain. The majority of individuals within the autism spectrum are deificient in glutathione. A deficiency of glutathione is correlated to excessive levels glutamates in the brain. The majority of individiduals within the autism spectrum have elevated levels of glutatmates. Excessive levels of glutamates overexcite neurons, leading to damage and neuronal death. Monosodium Glutamate (MSG) is frequently used in foods because it excites the receptors for taste in the mouth making food taste more flavorful. Unfortunately, this excitation does not stop with the mouth, and also excites receptors in the brain.







yIKES!

Swan
14th December 2014, 13:10
Autism Enzyme 7-Month Trial Study

The following report on a 7-month trial of Peptizyde and HN-Zyme is reprinted with the kind permission of the Enzymes and Autism Board, hosted by Yahoo Groups. The overwhelming majority of respondents saw noticeable improvements with Peptizyde and HN-Zyme Prime. Of 260 total respondents (100%) using these products for at least 3 weeks, 235 (90%) reported positive results, 14 (6%) reported negative results, and 11 (4%) reported inconclusive results.

Significant improvements were seen in eye contact, language, humor, foods tolerated, foods accepted, sleep, weight gain or loss, digestion, stools/bowels, overall appearance, transitioning, socialization, awareness, problem solving, short-term memory, flexibility in routine, range of interests, sound and light tolerance, sensory integration, spontaneous affection, and energy level among others.

Significant decreases were seen in aggression, hyperness, anxiety, self-stimming, self-injurious behavior, pain, and headaches among others.

http://www.autismcoach.com/autism-enzyme-7-month-trial-study/

Pam
27th December 2014, 19:42
I thought this was interesting and felt it deserves consideration. Does anyone have any thoughts about the following article?







Half of All Children Will Be Autistic by 2025, Warns Senior Research Scientist at MIT


Published: December 26, 2014

Source: Alliance for Natural Health




Why? Evidence points to glyphosate toxicity from the overuse of Monsanto’s Roundup herbicide on our food.

For over three decades, Stephanie Seneff, PhD, has researched biology and technology, over the years publishing over 170 scholarly peer-reviewed articles. In recent years she has concentrated on the relationship between nutrition and health, tackling such topics as Alzheimer’s, autism, and cardiovascular diseases, as well as the impact of nutritional deficiencies and environmental toxins on human health.

At a conference last Thursday, in a special panel discussion about GMOs, she took the audience by surprise when she declared, “At today’s rate, by 2025, one in two children will be autistic.” She noted that the side effects of autism closely mimic those of glyphosate toxicity, and presented data showing a remarkably consistent correlation between the use of Roundup on crops (and the creation of Roundup-ready GMO crop seeds) with rising rates of autism. Children with autism have biomarkers indicative of excessive glyphosate, including zinc and iron deficiency, low serum sulfate, seizures, and mitochondrial disorder.

A fellow panelist reported that after Dr. Seneff’s presentation, “All of the 70 or so people in attendance were squirming, likely because they now had serious misgivings about serving their kids, or themselves, anything with corn or soy, which are nearly all genetically modified and thus tainted with Roundup and its glyphosate.”

Dr. Seneff noted the ubiquity of glyphosate’s use. Because it is used on corn and soy, all soft drinks and candies sweetened with corn syrup and all chips and cereals that contain soy fillers have small amounts of glyphosate in them, as do our beef and poultry since cattle and chicken are fed GMO corn or soy. Wheat is often sprayed with Roundup just prior to being harvested, which means that all non-organic bread and wheat products would also be sources of glyphosate toxicity. The amount of glyphosate in each product may not be large, but the cumulative effect (especially with as much processed food as Americans eat) could be devastating. A recent study shows that pregnant women living near farms where pesticides are applied have a 60% increased risk of children having an autism spectrum disorder.

Other toxic substances may also be autism-inducing. You may recall our story on the CDC whistleblower who revealed the government’s deliberate concealment of the link between the MMR vaccine (for measles, mumps, and rubella) and a sharply increased risk of autism, particularly in African American boys. Other studies now show a link between children’s exposure to pesticides and autism. Children who live in homes with vinyl floors, which can emit phthalate chemicals, are more likely to have autism. Children whose mothers smoked were also twice as likely to have autism. Research now acknowledges that environmental contaminants such as PCBs, PBDEs, and mercury can alter brain neuron functioning even before a child is born.

This month, the USDA released a study finding that although there were detectable levels of pesticide residue in more than half of food tested by the agency, 99% of samples taken were found to be within levels the government deems safe, and 40% were found to have no detectable trace of pesticides at all. The USDA added, however, that due to “cost concerns,” it did not test for residues of glyphosate. Let’s repeat that: they never tested for the active ingredient in the most widely used herbicide in the world. “Cost concerns”? How absurd—unless they mean it will cost them too much in terms of the special relationship between the USDA and Monsanto. You may recall the revolving door between Monsanto and the federal government, with agency officials becoming high-paying executives—and vice versa! Money, power, prestige: it’s all there. Monsanto and the USDA love to scratch each others’ backs. Clearly this omission was purposeful.

In addition, as we have previously reported, the number of adverse reactions from vaccines can be correlated as well with autism, though Seneff says it doesn’t correlate quite as closely as with Roundup. The same correlations between applications of glyphosate and autism show up in deaths from senility.

Of course, autism is a complex problem with many potential causes. Dr. Seneff’s data, however, is particularly important considering how close the correlation is—and because it is coming from a scientist with impeccable credentials. Earlier this year, she spoke at the Autism One conference and presented many of the same facts; that presentation is available on YouTube.

Monsanto claims that Roundup is harmless to humans. Bacteria, fungi, algae, parasites, and plants use a seven-step metabolic route known as the shikimate pathway for the biosynthesis of aromatic amino acids; glyphosate inhibits this pathway, causing the plant to die, which is why it’s so effective as an herbicide. Monsanto says humans don’t have this shikimate pathway, so it’s perfectly safe.

Dr. Seneff points out, however, that our gut bacteria do have this pathway, and that’s crucial because these bacteria supply our body with crucial amino acids. Roundup thus kills beneficial gut bacteria, allowing pathogens to grow; interferes with the synthesis of amino acids including methionine, which leads to shortages in critical neurotransmitters and folate; chelates (removes) important minerals like iron, cobalt and manganese; and much more.

Even worse, she notes, additional chemicals in Roundup are untested because they’re classified as “inert,” yet according to a 2014 study in BioMed Research International, these chemicals are capable of amplifying the toxic effects of Roundup hundreds of times over.

Glyphosate is present in unusually high quantities in the breast milk of American mothers, at anywhere from 760 to 1,600 times the allowable limits in European drinking water. Urine testing shows Americans have ten times the glyphosate accumulation as Europeans.

“In my view, the situation is almost beyond repair,” Dr. Seneff said after her presentation. “We need to do something drastic.

Flash
27th December 2014, 20:29
This is clearly criminal in my views. And I know very well autism is directly linked with pesticides consumption and bad elimination as well as gut syndromes. The problem being that parents with autistic children have soooooo much time involved with their children that are very heavily demanding special attention that those same parents have no time left to combat the killers of their childen, and their children abilities.

In my views, putting children in the jail that is autism, being jailed in one's own body, not being able to communicate coherently, is worst than killing them stratightforwardly. this is a lifelong sentence those children have never asked for or done anything that warranties a lifelong jail sentence.

And add to this the lifelong jail sentence - guilt sentence and financial hardship of whole families having to help their son\daughter\brother and sister.

A death sentence not of the scientists, but of the CEO pocketing the money from their killing should be implemented.

Tesla_WTC_Solution
28th December 2014, 22:48
OH my god. I had not checked back here.
Thanks for the update and holy crap.

every day brings more weight to the burden but also more hope that we can change things

jerry
30th December 2014, 04:09
This is a thread I may or may not contribute to but I know its on I will share thanks Tesla

sheme
5th January 2015, 18:32
http://naturalsociety.com/epidemiologist-cdc-says-never-give-pregnant-wife-flu-shot/

Pam
11th April 2015, 15:22
sorry , this was a duplicate.

Tesla_WTC_Solution
11th May 2015, 15:58
I put this link in another thread but want it here too,
it's horrifying when it happens to the poor --


http://www.cnn.com/2015/05/10/health/mexico-vaccine-deaths/index.html

Hervé
24th January 2016, 14:50
Bumping (http://projectavalon.net/forum4/showthread.php?63627-File-It-Away-Right-Here-Before-You-Forget--A-Thread-for-Autism-Research-Paper-Links&p=916884&viewfull=1#post916884) with other versions on Dr. Stephanie Seneff's presentation:

MIT States That Half of All Children May be Autistic by 2025 due to Monsanto (http://journal-neo.org/2015/01/26/mit-states-that-half-of-all-children-may-be-autistic-by-2025/)

Author: Janet Phelan (http://journal-neo.org/author/janet-phelan/) 26.01.2015

[...]

And:

Monsanto’s Roundup and Autism (http://www.cryptogon.com/?p=45723)

December 30th, 2014


Correlations are not causation, but when they plot out as clearly as Stephanie Seneff has plotted them out with regard to autism and glyphosate, the key ingredient in Monsanto’s Roundup weed killer, they are impossible to ignore.
[...]


Related:

From Stephanie Seneff's Home page (http://people.csail.mit.edu/seneff/)

Information on Glyphosate (Roundup)
Glyphosate, Roundup, Glyphosate-Tolerance GM Soybeans, Chemical Extracted Soybean Food Oil/Soybean Powder Cause Serious Harm to Health of American/Chinese People. Compiled and translated by I-wan, Chen (cheniwan@cei.gov.cn). (Download) (http://people.csail.mit.edu/seneff/glyphosate/Chen_I_wan_Reference_info_glyphosate_June18_2014.pdf)

Glyphosate: The "Safe" Herbicide that's Making Us All Sick. July, 2015. Hawaii tour, sponsored in part by Seeds of Truth. (Video of Presentation) (https://www.youtube.com/watch?v=qYC6oyBglZI) (Powerpoint Slides) (http://people.csail.mit.edu/seneff/SeneffHawaiiSummer2015.pptx) (PDF Version) (http://people.csail.mit.edu/seneff/SeneffHawaiiSummer2015.pdf)

Roundup and GMO and the Rise of Modern Disease. Jan. 22, 2015. Talk in Honolulu, HI, sponsored by Seeds of Truth. (Powerpoint Slides) (http://people.csail.mit.edu/seneff/Oahu2015.pptx) (PDF Version) (http://people.csail.mit.edu/seneff/Oahu2015.pdf)

Roundup and GMOs: Are We Gambling with the Future of Food? July 29, 2014, Talk presented at the National Cheng Kung University, Tainan, Taiwan (Powerpoint Slides) (http://people.csail.mit.edu/seneff/glyphosate/Taiwan_July2014.pptx) (PDF Version) (http://people.csail.mit.edu/seneff/glyphosate/Taiwan_July2014.pdf)

Presentation at an Informational Hearing on Genetically Modified Organisms for the Agricultural and Rural Affairs Committee of the Pennsylvania legislature. (Powerpoint Slides) (http://people.csail.mit.edu/seneff/Harrisburg.pptx) (PDF Version) (http://people.csail.mit.edu/seneff/Harrisburg.pdf)

Is Roundup the Toxic Chemical that's Making Us All Sick? June 5, 2014, Groton School, Campbell Performing Arts Center, Groton MA. (Powerpoint Slides) (http://people.csail.mit.edu/seneff/glyphosate/Groton_Seneff.pptx) (PDF Version) (http://people.csail.mit.edu/seneff/glyphosate/Groton_Seneff.pdf)

"Sulfate Deficiency in Neurological Disease Following Aluminum and Glyphosate Exposure," Webinar presented on June 2, 2015, hosted by Jessica Sherman. (Powerpoint Slides) (http://people.csail.mit.edu/seneff/2015/SeneffJune2_2015.pptx) (PDF Version) (http://people.csail.mit.edu/seneff/2015/SeneffJune2_2015.pdf)

Presentation on Wednesday, May 27, 2015 in Taiwan, organized by the Green Formosa Front and sponsored by the HaoRan Foundation. (Powerpoint Slides) (http://people.csail.mit.edu/seneff/2015/Taiwan2015.pptx) (PDF Version) (http://people.csail.mit.edu/seneff/2015/Taiwan2015.pdf)

Presentation on glyphosate on April 28, 2014 hosted by the MIT and Wellesley Alumni Associations (Powerpoint Slides) (http://people.csail.mit.edu/seneff/California_glyphosate.pptx) (PDF Version) (http://people.csail.mit.edu/seneff/California_glyphosate.pdf)

Why Soy is Unhealthy: It's NOT what you Think! Slides of talk presented at Yale's 12th annual "Unite for Sight" Conference, Mar. 29, 2015. (Powerpoint Slides) (http://people.csail.mit.edu/seneff/glyphosate/SeneffYale2015.pptx)

Presentation on April 12, 2014 at Unite For Sight's 11th annual Global Health & Innovation Conference. (Powerpoint Slides) (http://people.csail.mit.edu/seneff/SeneffGlyphosateYale2014.pptx) (PDF Version) (http://people.csail.mit.edu/seneff/SeneffGlyphosateYale2014.pdf)

Presentation on March 26, 2014 at International Symposium on Vaccines in Nice, France: A Role for the Pineal Gland in Neurological Damage Following Aluminum-adjuvanted Vaccination (Powerpoint Slides) (http://people.csail.mit.edu/seneff/SeneffNice2014.pptx) (PDF Version) (http://people.csail.mit.edu/seneff/SeneffNice2014.pdf)

Presentation on March 16, 2014 at Physicians' Roundtable Conference in Tampa, FL. (Powerpoint Slides) (http://people.csail.mit.edu/seneff/glyphosate/SeneffTampaGlyphosate2014.pptx) (PDF Version) (http://people.csail.mit.edu/seneff/glyphosate/SeneffTampaGlyphosate2014.pdf)

Presentation on Oct 16, 2013 hosted by the Wellesley chapter of the League of Women Voters. Video. (https://www.youtube.com/watch?v=MqWwhggnbyw&feature=youtu.be#t=18m35s) Slides. (http://people.csail.mit.edu/seneff/glyphosate/glyphosate_wellesley.pptx)

326 page document by Sayer Ji - many references to the literature on why not to vaccinate. Click Here (http://www.greenmedinfo.com/sites/default/files/gpub_58635_anti_therapeutic_action_vaccination_all.pdf)

Nancy Swanson, Andre Leu, Jon Abrahamson and Bradley Wallet. Genetically engineered crops, glyphosate and the deterioration of health in the United States of America. Journal of Organic Systems, 9(2), 2014. Click Here (http://people.csail.mit.edu/seneff/Swanson_et_al_2014.pdf)

Compilation (by Rosemary Mason MB ChB FRCA) of data worldwide on effects of glyphosate on human health. Click Here (http://people.csail.mit.edu/seneff/glyphosate/glyphosate_report_by_RosemaryMason_March2015.pdf)

Former Monsanto employee put in charge of GMO papers at journal Click Here (http://earthopensource.org/index.php/news/148-former-monsanto-employee-put-in-charge-of-gmo-papers-at-journal)

Scientific journal withdraws Seralini paper on Roundup toxicity Click Here (http://www.examiner.com/article/scientific-journal-withdraws-s-ralini-paper-on-roundup-toxicity)

Autism Rates and Glyphosate Application Rates to Corn and Soy in the U.S. as A Function of Time. Click Here (http://people.csail.mit.edu/seneff/glyphosate/glyphosate.html)

Slides Presented to MIT Faculty at CSAIL Offsite Meeting on May 17, 2013, on autism and glyphosate. (Powerpoint Slides) (http://people.csail.mit.edu/seneff/WAPF_Slides_2012/offsite_Seneff.pptx) (PDF Version) (http://people.csail.mit.edu/seneff/WAPF_Slides_2012/Offsite_Seneff_Handout.pdf)

Violet
24th January 2016, 20:21
Thank you, Tesla.

Nat_Lee
17th March 2016, 03:03
Hi guys !
Flash wanted me to post this information for all the parents.




Flash: This video links lyme disease and autism, the researcher says that autism is often transgenerational lyme disease transmitted in the womb. 
THZhANfFnyY

Delight
7th May 2021, 01:07
This is really good news


Letterboard - 2.jpg
In 2016, AALIVE was introduced to a communication method for non-speaking autistics.

As our mentor, Elizabeth Vosseller from Growing Kids Therapy Center, defines it:

"Spelling to Communicate (https://www.aalive.org/spelling-to-communicate) teaches individuals with motor challenges the purposeful motor skills necessary to point to letters to spell as an alternative means of communication (AAC). The goal is to achieve synchrony between the brain and body. Skilled and rigorously trained communication partners teach purposeful motor skills using a hierarchy of verbal and gestural prompts. As motor skills improve through consistent practice, students progress from pointing to letters on letterboards to spell to typing on a keyboard. Accordingly, communication moves from concrete to abstract as motor skills progress."

We invite you to reach out to AALIVE to learn more about Spelling to Communicate or if you have any questions. AALIVE is proud to support our own center in Springfield, PA called Inside Voice. You can also find out more about Inside Voice here.

This week on the Highwire was a BEAUTIFUL story of how people who cannot speak may regain the ability to communicate through spelling. A MUST SEE!


https://thehighwire.com/watch/Highwire May 6, 2021 episode (https://thehighwire.com/watch/)FINDING THEIR VOICE
School Bans the Covid Vaccinated; What’s the Story with Covid Vaccine Shedding?; Florida is Winning!; Parents Calling New Program an “Autism Miracle”

#NoVaccinated #CentnerAcademy #StopTheShed #DeSantis #Underestimated #AutismMiracle

Broadcasted 5/6/21 2:00pm - 5/6/21 4:31pm

Finding their voice segment starts at 1:08:55

Sue (Ayt)
5th November 2022, 06:03
Tylenol products linked to autism epidemic:


http://www.autismcoach.com/tylenol-fueling-autism-epidemic/



Home
Article Database
Autism Scientific Research and News Articles
Tylenol Fueling Autism Epidemic?

Tylenol Fueling Autism Epidemic?

http://cdn3.bigcommerce.com/s-g6copot/product_images/uploaded_images/tylenol.jpg?t=1414073189

December 07, 2013. Tylenol, the supposedly safe alternative to aspirin for children, may be anything but. Researchers from the University of California, San Diego, found that among children who experienced an adverse reaction to the MMR vaccine (a vaccine which contains neurotoxic free glutamate), the children whose adverse vaccine reactions were treated with acetaminophen (Tylenol) were eight times more likely to develop an autism spectrum disorder than the children who were treated with ibuprofen (to see the pub med citation, click here).

I find it interesting to note that only a handful of children have suffered from Reyes Syndrome, but the FDA took stringent action to warn people not to use aspirin with their children, while FDA has not seen fit to take action to warn parents not to give their infants and young children Tylenol or to avoid it in pregnancy, and it is likely that huge numbers of children are being affected by it. (Note that Tylenol is not safe for anyone - it is the leading cause for calls to Poison Control Centers. In 2004, acetaminophen accounted for more than 56,000 emergency room visits, 2,600 hospitalizations and 458 deaths due to acute liver failure. Interestingly, the standard hospital protocol is to administer the supplement, N-Acetyl Cysteine, as an antidote. For a link to this paper, click here).

Tylenol depletes glutathione, the major free radical scavenger in the brain. The majority of individuals within the autism spectrum are deificient in glutathione. A deficiency of glutathione is correlated to excessive levels glutamates in the brain. The majority of individiduals within the autism spectrum have elevated levels of glutatmates. Excessive levels of glutamates overexcite neurons, leading to damage and neuronal death. Monosodium Glutamate (MSG) is frequently used in foods because it excites the receptors for taste in the mouth making food taste more flavorful. Unfortunately, this excitation does not stop with the mouth, and also excites receptors in the brain.







yIKES!

Updating this thread with this recent article about Tylenol (aka acetaminophen and paremectol) lawsuits:

Debate over possible acetaminophen-autism link heads to court

WASHINGTON, Oct. 28 (UPI) -- Debate over the growing scientific evidence that links women who took acetaminophen during pregnancy with giving birth to a child with autism is heading to the courtroom.

Backed by studies that tie use of the common pain reliever with autism in offspring, lawyers for thousands of affected families plan to take on some of the biggest drug retailers in America -- alleging they failed to warn of potential dangers when selling their products that contain acetaminophen.

Earlier this month, the U.S. Judicial Panel on Multidistrict Litigation ordered that 65 individual cases on the purported autism-acetaminophen link be consolidated into mass tort litigation to reduce the burden on individual courts and produce a consistent outcome.

Pending cases were assigned to Judge Denise L. Cote, of the U.S. District Court for the Southern District of New York, for pretrial hearings.

Instead of one mega-trial, mass tort cases like this have the parties agree to try a small number of "bellwether" cases to gauge jury reaction. Sometimes the matter is settled before those bellwether cases go to trial.

<snip>
At the heart of the dispute is a drug that tops $1 billion in annual U.S. sales.

Acetaminophen -- the most widely sold brand of which is Tylenol -- is estimated to be used by nearly two-thirds of pregnant women at some point during pregnancy.

In fact, as the most common drug ingredient in the United States, acetaminophen is found in 600-plus medicines, including prescription and over-the-counter pain relievers, fever reducers and sleep aids, as well as cough, cold and allergy medicines under brand names that include NyQuil, Excedrin, Alka-Seltzer and Robitussin.

Health professionals routinely tell women that acetaminophen is safe to take during pregnancy, especially to reduce high fever and severe pain that, if left untreated, may harm them or the developing fetus.

But women may be less well-advised when it comes to limiting acetaminophen use.
<snip>
The Food and Drug Administration, some medical groups, and Johnson & Johnson, which makes Tylenol, say further research is needed to firmly establish whether a link exists between neurobehavioral conditions and acetaminophen.

"We will always evaluate new data. At this time, we are not aware of conclusive evidence to support a causal link between acetaminophen use during pregnancy and the risk of adverse fetal outcomes," spokeswoman Meghan Harding of Johnson & Johnson Consumer Healthcare said in a statement to UPI.

According to Harding, the label on Johnson & Johnson's adult Tylenol products, in which acetaminophen is the active ingredient, states, "If pregnant or breast-feeding, ask a health professional before use."
<snip>
Emerging research

The takeaway for the public "is to know that many scientists and doctors are concerned about the emerging research and that pregnant women should be cautious and try to avoid the use of acetaminophen for mild discomfort and nuisance pain," Bauer said.

She added, "It is important to know that the FDA last reviewed the acetaminophen research in 2015. Much of the research was done after that."

According to Bauer, scientists know acetaminophen crosses the placenta and the blood-brain barrier.

"We now have consistent signals from numerous human epidemiologic and experimental in vivo and in vitro studies suggesting acetaminophen exposure during pregnancy increases the risk of the child having adverse neurodevelopmental conditions, to include ADHD and autism," she said.

As research methods have improved, the identified risks have gotten stronger, Bauer said.

Overall, earlier epidemiologic studies, which relied on maternal reporting of acetaminophen use, reported a 20% to 30% increased risk of autism and ADHD from taking the medication, she said.

Three recent studies that used biomarkers to assess acetaminophen exposure -- measuring its levels in umbilical cord plasma, maternal blood and meconium, a newborn's first feces -- identified risks about 10 times higher, Bauer said.

Moreover, "the majority of human observational studies that were able to investigate whether there was a dose-response relationship found one," she said.
<snip>
Overall, earlier epidemiologic studies, which relied on maternal reporting of acetaminophen use, reported a 20% to 30% increased risk of autism and ADHD from taking the medication, she said.

Three recent studies that used biomarkers to assess acetaminophen exposure -- measuring its levels in umbilical cord plasma, maternal blood and meconium, a newborn's first feces -- identified risks about 10 times higher, Bauer said.

Moreover, "the majority of human observational studies that were able to investigate whether there was a dose-response relationship found one," she said.

Read complete article here:
https://www.upi.com/amp/Health_News/2022/10/28/acetaminophen-pregnancy-autism-lawsuits/9701666296922/

Pam
5th November 2022, 11:09
Tylenol products linked to autism epidemic:


http://www.autismcoach.com/tylenol-fueling-autism-epidemic/



Home
Article Database
Autism Scientific Research and News Articles
Tylenol Fueling Autism Epidemic?

Tylenol Fueling Autism Epidemic?

http://cdn3.bigcommerce.com/s-g6copot/product_images/uploaded_images/tylenol.jpg?t=1414073189

December 07, 2013. Tylenol, the supposedly safe alternative to aspirin for children, may be anything but. Researchers from the University of California, San Diego, found that among children who experienced an adverse reaction to the MMR vaccine (a vaccine which contains neurotoxic free glutamate), the children whose adverse vaccine reactions were treated with acetaminophen (Tylenol) were eight times more likely to develop an autism spectrum disorder than the children who were treated with ibuprofen (to see the pub med citation, click here).

I find it interesting to note that only a handful of children have suffered from Reyes Syndrome, but the FDA took stringent action to warn people not to use aspirin with their children, while FDA has not seen fit to take action to warn parents not to give their infants and young children Tylenol or to avoid it in pregnancy, and it is likely that huge numbers of children are being affected by it. (Note that Tylenol is not safe for anyone - it is the leading cause for calls to Poison Control Centers. In 2004, acetaminophen accounted for more than 56,000 emergency room visits, 2,600 hospitalizations and 458 deaths due to acute liver failure. Interestingly, the standard hospital protocol is to administer the supplement, N-Acetyl Cysteine, as an antidote. For a link to this paper, click here).

Tylenol depletes glutathione, the major free radical scavenger in the brain. The majority of individuals within the autism spectrum are deificient in glutathione. A deficiency of glutathione is correlated to excessive levels glutamates in the brain. The majority of individiduals within the autism spectrum have elevated levels of glutatmates. Excessive levels of glutamates overexcite neurons, leading to damage and neuronal death. Monosodium Glutamate (MSG) is frequently used in foods because it excites the receptors for taste in the mouth making food taste more flavorful. Unfortunately, this excitation does not stop with the mouth, and also excites receptors in the brain.







yIKES!

Updating this thread with this recent article about Tylenol (aka acetaminophen and paremectol) lawsuits:

Debate over possible acetaminophen-autism link heads to court

WASHINGTON, Oct. 28 (UPI) -- Debate over the growing scientific evidence that links women who took acetaminophen during pregnancy with giving birth to a child with autism is heading to the courtroom.

Backed by studies that tie use of the common pain reliever with autism in offspring, lawyers for thousands of affected families plan to take on some of the biggest drug retailers in America -- alleging they failed to warn of potential dangers when selling their products that contain acetaminophen.

Earlier this month, the U.S. Judicial Panel on Multidistrict Litigation ordered that 65 individual cases on the purported autism-acetaminophen link be consolidated into mass tort litigation to reduce the burden on individual courts and produce a consistent outcome.

Pending cases were assigned to Judge Denise L. Cote, of the U.S. District Court for the Southern District of New York, for pretrial hearings.

Instead of one mega-trial, mass tort cases like this have the parties agree to try a small number of "bellwether" cases to gauge jury reaction. Sometimes the matter is settled before those bellwether cases go to trial.

<snip>
At the heart of the dispute is a drug that tops $1 billion in annual U.S. sales.

Acetaminophen -- the most widely sold brand of which is Tylenol -- is estimated to be used by nearly two-thirds of pregnant women at some point during pregnancy.

In fact, as the most common drug ingredient in the United States, acetaminophen is found in 600-plus medicines, including prescription and over-the-counter pain relievers, fever reducers and sleep aids, as well as cough, cold and allergy medicines under brand names that include NyQuil, Excedrin, Alka-Seltzer and Robitussin.

Health professionals routinely tell women that acetaminophen is safe to take during pregnancy, especially to reduce high fever and severe pain that, if left untreated, may harm them or the developing fetus.

But women may be less well-advised when it comes to limiting acetaminophen use.
<snip>
The Food and Drug Administration, some medical groups, and Johnson & Johnson, which makes Tylenol, say further research is needed to firmly establish whether a link exists between neurobehavioral conditions and acetaminophen.

"We will always evaluate new data. At this time, we are not aware of conclusive evidence to support a causal link between acetaminophen use during pregnancy and the risk of adverse fetal outcomes," spokeswoman Meghan Harding of Johnson & Johnson Consumer Healthcare said in a statement to UPI.

According to Harding, the label on Johnson & Johnson's adult Tylenol products, in which acetaminophen is the active ingredient, states, "If pregnant or breast-feeding, ask a health professional before use."
<snip>
Emerging research

The takeaway for the public "is to know that many scientists and doctors are concerned about the emerging research and that pregnant women should be cautious and try to avoid the use of acetaminophen for mild discomfort and nuisance pain," Bauer said.

She added, "It is important to know that the FDA last reviewed the acetaminophen research in 2015. Much of the research was done after that."

According to Bauer, scientists know acetaminophen crosses the placenta and the blood-brain barrier.

"We now have consistent signals from numerous human epidemiologic and experimental in vivo and in vitro studies suggesting acetaminophen exposure during pregnancy increases the risk of the child having adverse neurodevelopmental conditions, to include ADHD and autism," she said.

As research methods have improved, the identified risks have gotten stronger, Bauer said.

Overall, earlier epidemiologic studies, which relied on maternal reporting of acetaminophen use, reported a 20% to 30% increased risk of autism and ADHD from taking the medication, she said.

Three recent studies that used biomarkers to assess acetaminophen exposure -- measuring its levels in umbilical cord plasma, maternal blood and meconium, a newborn's first feces -- identified risks about 10 times higher, Bauer said.

Moreover, "the majority of human observational studies that were able to investigate whether there was a dose-response relationship found one," she said.
<snip>
Overall, earlier epidemiologic studies, which relied on maternal reporting of acetaminophen use, reported a 20% to 30% increased risk of autism and ADHD from taking the medication, she said.

Three recent studies that used biomarkers to assess acetaminophen exposure -- measuring its levels in umbilical cord plasma, maternal blood and meconium, a newborn's first feces -- identified risks about 10 times higher, Bauer said.

Moreover, "the majority of human observational studies that were able to investigate whether there was a dose-response relationship found one," she said.

Read complete article here:
https://www.upi.com/amp/Health_News/2022/10/28/acetaminophen-pregnancy-autism-lawsuits/9701666296922/

Really interesting. I know in the US tylenol is handed out like candy. They also frequently recommend giving it to babies. In fact it used to be common to advise giving a kid tylenol if they were under the weather after receiving vaccines. It gives one a feeling of safety about taking it for any and every ache and pain.

The one question it doesn't answer is the kids that were perfectly normal, received their "scheduled" vaccines and were never the same again.

I was just thinking yesterday, that when I was in elementary school, throughout the whole process I only remember 2 kids that had fairly severe behavioral issues. I never remember anyone having to be given their meds during school. There was no need to have a special ed, or maybe they did for profoundly disabled kids and I just wasn't aware of it. I never saw one kid that fit the autism diagnoses.

So it may be that multiple reasons, but if one goes back to the source of all of this, as far as I can see drugs are involved in some way. Very interesting info, Sue.