Fairy Friend
31st October 2013, 08:28
Some cures to Depression
It has been said throughout history in some shape or form, 'It's not the disease that kills you it's the medicine.' What are some alternatives to psychotropics for depression.
My mom says it's exercise. She is a great-grandma at 80. She is on no medication except recently she was put on a low dose blood pressure medicine. It is unwise to argue with her, it's just not done. She says exercise, a healthy diet and keep busy, be productive. I agree of course. I concur with exercise, many here on this website have used these exact words practically. Stop channeling my mother. But I also use and like tech talk, with exercise, it will help process vitamins and gets your lymphatic system to work and muscles to detoxify. Move around. Same thing.
Let's focus on a specific amino acid that links to helping with alleviate depression: L-Tryptophan. L-Tryptophan is the precursor to serotonin and melatonin. This is in turkey, chicken, most meats and makes you sleepy. Also, when you warm milk, you break proteins down with the heat and it releases the amino acids like tryptophan for better absorption. Old remedy that works. Most people think meat with protein but plants have proteins too. Bananas, peanuts and pumpkin seeds are sources. Many food sources.
This is essential for life to go on. We need it to make protein and protein is life. We have to ingest it, our body cannot make it. A recommended dose 1-6 grams for an adult or 500-1000 mg (0.5-1gm) for a pregnant woman.
Banned in the US, although I have recently checked and in 2002 it was allowed in research labs and could be gotten under the prescription name Tryptan but it seems only prescribed after traditional psychotropics had failed. I here not banned in England, Canada, ?Mexico. It maybe back on the market. I hope so.
L-Tryptophan makes you calm, relaxed and sleepy. Tryptophan is a precursor to serotonin but the body will first convert it to Niacin (vitamin B3) and will supply this first if you are deficient in Niacin. Niacin is a major player in natural detoxing in the liver, skin and I believe kidneys. Understand that if it shunting to Niacin production that is an issue that should be addressed also. You also need, Vitamin C and Vitamin B6 (pyridoxine) as well as Folic acid (vitamin B5), magnesium and glutamine and are essential to convert Tryptophan into serotonin (a neurotransmitter). Neither Serotonin nor especially tryptophan stay in the body long. For this reason tryptophan cannot accumulate to toxic levels, ok never say never, I know. Vitamin B12 as well I hear helps.
In my mind 5-HTP (hydroxy group on the 5th carbon of the tryptophan molecule) was a way around this ban of Tryptophan. It is a close derivative that is not foreign to the body, a supplement not a drug. An intermediary form. We convert tryptophan into this before it gets turned into serotonin. I do not know the ½ life of this compound in the body. Nor the reaction rate to see how easily it converts back to Tryptophan. It does readily cross the blood/brain barrier.
Serotonin is converted into melatonin (a neurohormone) which regulates sleep cycles. Another supplement that helps you sleep. It also can be limited if Tryptophan is limited.
Also, if we artificially make it, it should be grade A with no contaminants. You cannot take L-Tryptophan or 5-HTP with Prozac. It will cause the serotonin syndrome.
We have a second system that can use the sunlight's energy to convert L-Tryptophan directly to serotonin in the skin. Bypassing the need for as much vitamins C and B6 and using light energy instead.
Serotonin also plays a role in wound healing being released when platelets come in contact with collagen fibers. Scab formation in other words. Serotonin then causes muscles in the nearby blood vessels to contract and constrict to reduce bleeding.
Serotonin also, controls muscular movement in the gut. And when sieve tube elements undergo apoptosis tryptophan is converted to auxins (a phytohormone).
Of all the Amino Acids, Tryptophan is the least able to cross the blood/brain barrier. The brain is separated by the blood/ brain barrier which protects it yes, but it is more dependent on proper long term nutrition and health for this same reason.
I know a trick. Fruit juice with ½ teaspoon of sugar will trigger insulin release assisting the tryptophan molecule across the blood/ brain barrier.
I know another trick. Chromium picolinate. You can buy amino acids at health stores which has L-Tryptophan in it. It has all the amino acids and you cannot remove the L-Tryptophan. Buy high dose, grade A, amino acids to get a higher level of Tryptophan. Take Chromium picolinate with the amino acids which facilitates absorption of the other amino acids into the muscles tissue that would compete with tryptophan for access to the brain. Which is why you loose weight, it builds the muscles but it raises the level of Tryptophan in the blood so it crosses the blood/brain barrier and gets into the brain more.
It's Halloween, so a couple of tricks are in alignment.
Mega-stress vitamins, or B complexes, are also linked to helping alleviate depression. The key word stress. Whether it is emotional stress (like the loss of a loved one), physical (like toxins in the body), mental (like work stress) or spiritual (like abuse), the body has similar, responses like with adrenal glands, hormones, disrupted sleep patterns, immune suppression, heart stress, vitamin depletion. Again exercise helps balance and restore proper levels of vitamins/minerals/amino acids. So if you feel “weird” exercise helps, when taking mega doses. Lower doses also help. Remember high doses of B vitamins for over a month can cause liver damage.
The disorders Fructose malabsorption and Lactose intolerance cause improper absorption of tryptophan in the intestine, reduced levels of tryptophan in the blood and increase depression or increase the odds of it occurring.
In a previous post on prozac, I theorized that the serotonin level was tightly regulated with a positive and negative feedback loop. In bacteria that synthesize tryptophan, high cellular levels of this amino acid activate a repressor protein, which binds to the tryptophan operon.* Binding of this repressor to the tryptophan operon prevents transcription of downstream DNA that codes for the enzymes involved in the biosynthesis of tryptophan. So high levels of tryptophan prevent tryptophan synthesis through a negative feedback loop and, when the cell's tryptophan levels are reduced, transcription from the tryptophan operon resumes. The genetic organization of the tryptophan operon thus permits tightly regulated and rapid responses to changes in the cell's internal and external tryptophan levels. Ok bacteria, not humans but the limb I felt out on before, is a little more solid to me.
*Gollnick P, Babitzke P, Antson A, Yanofsky C (2005). "Complexity in regulation of tryptophan biosynthesis in Bacillus subtilis". Annu. Rev. Genet. 39: 47–68. doi:10.1146/annurev.genet.39.073003.093745. PMID 16285852.
I have a theory that Tyrosine depletion is what causes 'baby blues'. I am out on a limb with little evidence to support me. It is the other essential amino acid we need. Pregnancy can really deplete the mother of many things.
Dogs change your serotonin levels. Even Dr. Cramer (I refer to him as Dr. Prozac sometimes as he brought it out to the public) was quoted. OK, if my enemy agrees with me, there is something to this. I believe the key is that they give unconditional love to you. Receiving unconditional love will adjust your serotonin levels and balance them.
Talk therapy can rewire you. That works in both directions. Good or bad, so don't give your power away. Mind is a powerful tool. There is a publication showing that this is true with brain scans.
However it should be noted, side effects from very large doses of L-Tryptophan are drowsiness the next morning, bizarre or strange dreams (rare), increase blood pressure, aggressiveness (this rare side effect can occur in the absence of sufficient supply of nutrients needed to convert tryptophan to serotonin). Side effects disappear in 24 hours.
I feel linked to the eosinophilia- myalgia syndrome or EMS in 1989 was due to contaminants and/or excess histamine and was directly linked to a Japanese company.
Helping depression was my hope. Not the catch all be all of all answers. I am currently, always trying to improve my health. As my mother tells me to. Wait. Is that why you people are channeling my mother and practical sage advice? Fairy Friend
It has been said throughout history in some shape or form, 'It's not the disease that kills you it's the medicine.' What are some alternatives to psychotropics for depression.
My mom says it's exercise. She is a great-grandma at 80. She is on no medication except recently she was put on a low dose blood pressure medicine. It is unwise to argue with her, it's just not done. She says exercise, a healthy diet and keep busy, be productive. I agree of course. I concur with exercise, many here on this website have used these exact words practically. Stop channeling my mother. But I also use and like tech talk, with exercise, it will help process vitamins and gets your lymphatic system to work and muscles to detoxify. Move around. Same thing.
Let's focus on a specific amino acid that links to helping with alleviate depression: L-Tryptophan. L-Tryptophan is the precursor to serotonin and melatonin. This is in turkey, chicken, most meats and makes you sleepy. Also, when you warm milk, you break proteins down with the heat and it releases the amino acids like tryptophan for better absorption. Old remedy that works. Most people think meat with protein but plants have proteins too. Bananas, peanuts and pumpkin seeds are sources. Many food sources.
This is essential for life to go on. We need it to make protein and protein is life. We have to ingest it, our body cannot make it. A recommended dose 1-6 grams for an adult or 500-1000 mg (0.5-1gm) for a pregnant woman.
Banned in the US, although I have recently checked and in 2002 it was allowed in research labs and could be gotten under the prescription name Tryptan but it seems only prescribed after traditional psychotropics had failed. I here not banned in England, Canada, ?Mexico. It maybe back on the market. I hope so.
L-Tryptophan makes you calm, relaxed and sleepy. Tryptophan is a precursor to serotonin but the body will first convert it to Niacin (vitamin B3) and will supply this first if you are deficient in Niacin. Niacin is a major player in natural detoxing in the liver, skin and I believe kidneys. Understand that if it shunting to Niacin production that is an issue that should be addressed also. You also need, Vitamin C and Vitamin B6 (pyridoxine) as well as Folic acid (vitamin B5), magnesium and glutamine and are essential to convert Tryptophan into serotonin (a neurotransmitter). Neither Serotonin nor especially tryptophan stay in the body long. For this reason tryptophan cannot accumulate to toxic levels, ok never say never, I know. Vitamin B12 as well I hear helps.
In my mind 5-HTP (hydroxy group on the 5th carbon of the tryptophan molecule) was a way around this ban of Tryptophan. It is a close derivative that is not foreign to the body, a supplement not a drug. An intermediary form. We convert tryptophan into this before it gets turned into serotonin. I do not know the ½ life of this compound in the body. Nor the reaction rate to see how easily it converts back to Tryptophan. It does readily cross the blood/brain barrier.
Serotonin is converted into melatonin (a neurohormone) which regulates sleep cycles. Another supplement that helps you sleep. It also can be limited if Tryptophan is limited.
Also, if we artificially make it, it should be grade A with no contaminants. You cannot take L-Tryptophan or 5-HTP with Prozac. It will cause the serotonin syndrome.
We have a second system that can use the sunlight's energy to convert L-Tryptophan directly to serotonin in the skin. Bypassing the need for as much vitamins C and B6 and using light energy instead.
Serotonin also plays a role in wound healing being released when platelets come in contact with collagen fibers. Scab formation in other words. Serotonin then causes muscles in the nearby blood vessels to contract and constrict to reduce bleeding.
Serotonin also, controls muscular movement in the gut. And when sieve tube elements undergo apoptosis tryptophan is converted to auxins (a phytohormone).
Of all the Amino Acids, Tryptophan is the least able to cross the blood/brain barrier. The brain is separated by the blood/ brain barrier which protects it yes, but it is more dependent on proper long term nutrition and health for this same reason.
I know a trick. Fruit juice with ½ teaspoon of sugar will trigger insulin release assisting the tryptophan molecule across the blood/ brain barrier.
I know another trick. Chromium picolinate. You can buy amino acids at health stores which has L-Tryptophan in it. It has all the amino acids and you cannot remove the L-Tryptophan. Buy high dose, grade A, amino acids to get a higher level of Tryptophan. Take Chromium picolinate with the amino acids which facilitates absorption of the other amino acids into the muscles tissue that would compete with tryptophan for access to the brain. Which is why you loose weight, it builds the muscles but it raises the level of Tryptophan in the blood so it crosses the blood/brain barrier and gets into the brain more.
It's Halloween, so a couple of tricks are in alignment.
Mega-stress vitamins, or B complexes, are also linked to helping alleviate depression. The key word stress. Whether it is emotional stress (like the loss of a loved one), physical (like toxins in the body), mental (like work stress) or spiritual (like abuse), the body has similar, responses like with adrenal glands, hormones, disrupted sleep patterns, immune suppression, heart stress, vitamin depletion. Again exercise helps balance and restore proper levels of vitamins/minerals/amino acids. So if you feel “weird” exercise helps, when taking mega doses. Lower doses also help. Remember high doses of B vitamins for over a month can cause liver damage.
The disorders Fructose malabsorption and Lactose intolerance cause improper absorption of tryptophan in the intestine, reduced levels of tryptophan in the blood and increase depression or increase the odds of it occurring.
In a previous post on prozac, I theorized that the serotonin level was tightly regulated with a positive and negative feedback loop. In bacteria that synthesize tryptophan, high cellular levels of this amino acid activate a repressor protein, which binds to the tryptophan operon.* Binding of this repressor to the tryptophan operon prevents transcription of downstream DNA that codes for the enzymes involved in the biosynthesis of tryptophan. So high levels of tryptophan prevent tryptophan synthesis through a negative feedback loop and, when the cell's tryptophan levels are reduced, transcription from the tryptophan operon resumes. The genetic organization of the tryptophan operon thus permits tightly regulated and rapid responses to changes in the cell's internal and external tryptophan levels. Ok bacteria, not humans but the limb I felt out on before, is a little more solid to me.
*Gollnick P, Babitzke P, Antson A, Yanofsky C (2005). "Complexity in regulation of tryptophan biosynthesis in Bacillus subtilis". Annu. Rev. Genet. 39: 47–68. doi:10.1146/annurev.genet.39.073003.093745. PMID 16285852.
I have a theory that Tyrosine depletion is what causes 'baby blues'. I am out on a limb with little evidence to support me. It is the other essential amino acid we need. Pregnancy can really deplete the mother of many things.
Dogs change your serotonin levels. Even Dr. Cramer (I refer to him as Dr. Prozac sometimes as he brought it out to the public) was quoted. OK, if my enemy agrees with me, there is something to this. I believe the key is that they give unconditional love to you. Receiving unconditional love will adjust your serotonin levels and balance them.
Talk therapy can rewire you. That works in both directions. Good or bad, so don't give your power away. Mind is a powerful tool. There is a publication showing that this is true with brain scans.
However it should be noted, side effects from very large doses of L-Tryptophan are drowsiness the next morning, bizarre or strange dreams (rare), increase blood pressure, aggressiveness (this rare side effect can occur in the absence of sufficient supply of nutrients needed to convert tryptophan to serotonin). Side effects disappear in 24 hours.
I feel linked to the eosinophilia- myalgia syndrome or EMS in 1989 was due to contaminants and/or excess histamine and was directly linked to a Japanese company.
Helping depression was my hope. Not the catch all be all of all answers. I am currently, always trying to improve my health. As my mother tells me to. Wait. Is that why you people are channeling my mother and practical sage advice? Fairy Friend