Researchers Discover Why Pesticide Exposure Increases Risk Of Parkinson’s

[dynamo]

by Brandon Turbeville, Natural Blaze

A new study coming out of the University of Guelph appears to have discovered why exposure to pesticides increases a person’s risk of developing Parkinson’s disease.

While many studies in the past have demonstrated a link between Paraquat and Maneb (two commonly used agrochemicals) and Parkinson’s, this new study actually investigates the process and form that link takes within the cells themselves.

Professor Scott Ryan, lead researcher of the study, has determined that low-level of exposure to pesticides disrupts cells in such a way that mimics the mutations that cause Parkinson’s.

When the effects of the chemicals are taken in concert with a genetic predisposition to Parkinson’s, the risk of Parkinson’s onset is drastically increased.

“People exposed to these chemicals are at about a 250-per-cent higher risk of developing Parkinson’s disease than the rest of the population,” said Ryan, a professor in the Department of Molecular and Cellular Biology.

“We wanted to investigate what is happening in this susceptible population that results in some people developing the disease.”

Paraquat and Maneb are used on a variety of Canadian crops with the former being used on crops during the growth period and the latter used in order to prevent spoiling after harvest.

The study, which was published in the Federation of American Societies for Experimental Biology, used stem cells from people with Parkinson’s disease using a mutation in a gene called synuclein which is associated with an increased risk of the disease. The study also used normal embryonic stem cells in which the mutation was introduced via gene editing.

“Until now, the link between pesticides and Parkinson’s disease was based primarily on animal studies as well as epidemiological research that demonstrated an increased risk among farmers and others exposed to agricultural chemicals,” said Ryan. “We are one of the first to investigate what is happening inside human cells.”

Ryan’s research team made dopamine-producing neurons — the neurons affected by Parkinson’s — from both types of the stem cells and then exposed them to the chemicals.

The exposure of the neurons to the chemicals prevented energy-producing mitochondria from moving where they need to go inside the cells which in turn depleted the neurons of energy.

According to the University of Guelph press release, “Neurons from the Parkinson’s patients and those in which the genetic risk factor was introduced were impaired at doses below the U.S. Environmental Protection Agency’s reported lowest observed effect level. Higher doses are needed to impair function in normal neurons.”

“People with a predisposition for Parkinson’s disease are more affected by these low level exposures to agrochemicals and therefore more likely to develop the disease,” said Ryan. “This is one of the reasons why some people living near agricultural areas are at a higher risk.”

Ryan stated that the findings indicate that the current acceptable levels of these two agrochemicals should be reassessed.

“This study shows that everyone is not equal, and these safety standards need to be updated in order to protect those who are more susceptible and may not even know it.”

Brandon Turbeville – article archive here – is an author out of Florence, South Carolina. He is the author of six books, Codex Alimentarius — The End of Health Freedom, 7 Real Conspiracies,Five Sense Solutions and Dispatches From a Dissident, volume 1 and volume 2, The Road to Damascus: The Anglo-American Assault on Syria,and The Difference it Makes: 36 Reasons Why Hillary Clinton Should Never Be President. Turbeville has published over 1,000 articles dealing on a wide variety of subjects including health, economics, government corruption, and civil liberties. Brandon Turbeville’s podcast Truth on The Tracks can be found every Monday night 9 pm EST at UCYTV. He is available for radio and TV interviews. Please contact activistpost (at) gmail.com.

[Cardillac]

if my read sources are correct the most common symptoms of poisoning (regardless of source) are paralysis and palsies-

Larry

[amor]

Codex Alimentarius is mentioned in Stopthecrime.net. I remember it spoke about how vitamins would be used to kill instead of help.

[Franny]

So relieved they have finally discovered that poison is...poison.

[gini]

The Alarming Rise in Parkinson’s Disease with Dr. Ray Dorsey | The Empowering Neurologist EP. 167----

Source: https://youtube.com/watch?v=nfsZOmSYJoo

DavidPerlmutterMD


Jun 27, 2023 The Empowering Neurologist with David Perlmutter, MD
Welcome one and all to another enlightening episode of The Empowering Neurologist. Joining us is Dr. Ray Dorsey, Professor of Neurology at the University of Rochester, a stalwart advocate for Parkinson's disease, and a renowned researcher in the field. With a profound belief in the power of awareness and knowledge, Dr. Dorsey dedicates his life to a cause that is impacting millions globally. He stands at the forefront of the fight against Parkinson's disease, a fight that is becoming increasingly critical as we see a staggering rise in the incidence of this condition.

Dr. Dorsey is not just an accomplished physician but also an engaging author. His groundbreaking book, Ending Parkinson’s Disease, is a critical exploration that sheds light on this global health crisis. It offers an enlightening perspective on Parkinson's disease and, so importantly as we discuss in this episode, its modifiable risk factors, raising consciousness and hope about this life-altering condition.

His book is an earnest appeal to policymakers, researchers, physicians, and the general public to recognize the escalating crisis and join the battle to end Parkinson's. It also serves as a testament to his belief in our collective ability to mitigate this crisis, beginning with understanding the risk factors that we can change.

We delve into the comprehensive world of Ending Parkinson’s Disease, discuss the modifiable risk factors, and explore ways to curb the skyrocketing incidences of Parkinson's. It is our shared responsibility, and understanding is the first step.--Timestamps

0:00 Intro
0:50 Rise in Parkinson’s
3:20 MPTP
8:10 Trichloroethylene (TCE)
13:14 Call to Action
16:19 Prevention of Parkinson’s
32:00 Caffeine and Smoking
37:25 Head Trauma
39:27 Conclusion


Dr. Ray Dorsey is the David M. Levy Professor of Neurology at the University of Rochester. Ray is working to identify and eliminate the root causes of Parkinson’s disease. His research on brain diseases and digital health has been published in leading academic journals and featured in multiple news outlets. In 2020, Ray and his colleagues wrote Ending Parkinson’s Disease, a book that provides a prescription for ending the world’s fastest growing brain disease.

Ray previously directed the movement disorders division and neurology telemedicine at Johns Hopkins and worked as a consultant for McKinsey & Company. In 2015, the White House recognized him as a “Champion for Change” for Parkinson’s disease.