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Thread: Glyphosate remediation

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    Default Re: Glyphosate remediation

    It seemed to me that taking glycine supplements might help detox and found ways it may?



    Quote How to detox glyphosate (Roundup) from your body
    Posted on February 6, 2019 by Cat


    I am strongly opposed to use of the plant-killer glyphosate, because of the harm it does to our bodies from intake of GMO foods, and from its use as a desiccant before harvesting grain crops. Also because of the harm it does to our soil and environment.

    Now I have some good news: you can detox your body from glyphosate, using several methods. This article is mainly about using a simple daily dose of glycine (an amino acid) to detox, and how to test for glyphosate levels in your body.

    Includes: 1. Glycine and glyphosate, and detox methods; 2. Testing methods for glyphosate levels you body
    See also: 1. Natural Healing Remedies Menu; 2. The EssentiaList articles on Glyphosate (written by Cat)
    Printable pdf version of this article: How to Detox Glyphosate from your Body (pdf, 020919 update)
    Glycine and glyphosate
    The main way glyphosate harms our bodies, is by substituting for glycine in our body’s peptides and proteins (such as enzymes, collagen, etc.). (1,2) That is, glyphosate is an analog of the amino acid, glycine. The chemical formulas are (note the similarities as indicated in purple-bold) (3):

    glycine amino acid is: NH2‐CH2‐COOH;
    glyphosate is: H2(PO3)-CH2–NH-CH2-COOH
    This similarity allows glyphosate to take glycine’s place in peptides and proteins, causing all kinds of havoc. Glycine is found in all parts of the body; for example, it is part of collagen and gelatin. Substitution by glyphosate can easily explain links with (2):

    “diabetes, obesity, asthma, chronic obstructive pulmonary disease (COPD), pulmonary edema, adrenal insufficiency, hypothyroidism, Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), Parkinson’s disease, prion diseases, lupus, mitochondrial disease, non-Hodgkin’s lymphoma, neural tube defects, infertility, hypertension, glaucoma, osteoporosis, fatty liver disease and kidney failure.”

    How to detox from glyphosate
    The good news: you can detox your body from toxic glyphosate, by increasing your dietary intake of glycine. Your body builds new peptides and proteins every day to replace aging ones, or for new uses. An easy way to ensure your body uses glycine and not glyphosate is by flooding it with glycine. Meanwhile, the aging peptides/proteins containing glyphosate are flushed from your body.

    Taking glycine supplementally can be very effective. Here are two suggestions:

    add glycine powder to a smoothie, shake, or fresh veggie juices (such as for a juice fast – see below);
    use it as an alternative sweetener for coffee, tea, and other beverages, because it is slightly sweet.
    Per Mercola’s article (1), “Dr. Dietrich Klinghardt recommends taking 1 teaspoon (4 grams) of glycine powder twice a day for a few weeks and then lower the dose to one-fourth teaspoon (1 gram) twice a day. This forces the glyphosate out of your system, allowing it to be eliminated through your urine.”

    Or you can take collagen supplementally, because it is an excellent source of glycine. Just be sure the source of collagen is from grass-fed/pasture-raised meat sources (conventionally raised livestock are fed Roundup-resistant soy and grains that are heavily contaminated with Roundup, which ends up in their muscles (meat)).

    IMPORTANT NOTE: Using glycine to detox will not work for other brands of herbicides/pesticides, unless they too contain glycine in their structure.

    Cat’s testing note: I have not yet tried this detox method, but I will do that soon, after getting both a hair analysis and radionics tests (see Testing, below) to determine my starting levels, and will report my results over time.

    Other detox methods:

    Easy Health Options (8) recommends first doing a pre-detox of your intestines using Miralax to create liquid stools. They also recommend sweating in a sauna, and doing a liver detox with specific herbs and supplements.

    A veggie-juice fast such as that offered by Wellness Education Center (WEC) in Kalispell helps with many different detox needs; I would recommend doing this glycine detox along with the WEC fast (add glycine powder to the juices).

    Bonuses with increasing glycine intake:
    Impact on glutathione:

    One of the most important peptides containing glycine is glutathione, a major antioxidant and detox agent made by the body, and essential for the liver’s detox ability. Glutathione is comprised of three amino acids: glycine, L-glutamine, and L-cysteine. When you take glycine supplementally, you help increase glutathione production, which improves your ability to detox toxic substances.

    If glyphosate has taken glycine’s place in glutathione, that lessens your body’s ability to detox, not only from glyphosate, but from many other toxins as well. By flooding your body with glycine, you have a double-impact: restoring glycine to peptides/proteins, and restoring glutathione’s ability to detox your body from the damage created by glyphosate.

    Impact on glycine/methionine balance in our bodies:

    According to Chris Masterjohn, PhD. (10), “maintaining proper dietary balance between [glycine and methionine] is also important because too much methionine represses glycine. The former is “especially abundant in eggs, dairy, meat, poultry, and fish. Glycine is especially abundant in skin and bones.” Unfortunately many of us avoid skin and bones in our meals; “for example, skinless, boneless chicken breast is rich in methionine, but the glycine-rich skin and bones have been removed.”

    For those who don’t eat enough skin and bones (as in stock and bone-broth), increasing glycine intake can help restore the balance and benefits of both, noting that (10):

    — Methionine helps prevent fatty liver disease and improves mental flexibility. It can help cool our anxiety or lift us from depression;

    — Glycine helps stabilize our blood sugar, and helps to prevent us from drifting into endless distractions. It promotes healthy sleep, and it revitalizes our skin and bones.

    Glycine supplement examples
    Here are a few you can check out. Go to iherb(dot)com (link disguised), and search for the following codes:

    Powders:
    NOW-00225 for NOW-brand glycine powder
    CAR-06835 for Carlson’s-brand glycine powder
    Capsules:
    NOW-00107 for NOW-brand glycine in capsules
    THR-51202 for Thorne-brand glycine in capsules
    SOL-01370 for Solgar-brand glycine in capsules
    I recommend the powder because it is easier to adjust the amount you take.

    Another form of glycine is its salt form, such as magnesium glycinate, but I am still researching its ability to detox glyphosate.

    Testing for glyphosate levels in your body
    We are all exposed to glyphosate – it’s unavoidable because it is everywhere. Even certified Organic foods are contaminated by drift from nearby spraying. We were safe from drift, here in NW Montana, until local farmers started growing GMO canola. So you may as well assume you have enough glyphosate to be concerned.

    You can minimize your exposure to glyphosate by preparing all your meals using foods you grow/raise yourself, but in this day and age, that is difficult.

    There are several recommended tests for your body; each provides information for a specific range of exposure over time (4a,5,6):

    Hair Testing shows your exposure to pesticides over a period of 90-120 days;
    Urine Testing shows your exposure for approximately 14-21 days; and
    Blood Testing shows your exposure for 2-3 days.
    Breast Milk Testing if you are nursing (exposure time not provided) (7)
    Hair Testing has several advantages (6):

    Easy collection
    Easy transport
    Enables continuous cost effective bio-monitoring over a year: 4 samples vs 100 for blood vs 26 for urine
    You can also have your water tested, as it is one source of exposure close to home.

    Labs:
    Detox Project offers:
    hair testing (Glyphosate test includes glyphosate, AMPA, and glufosinate); other pesticide tests are also available (4b),
    food and water testing (4c)
    Great Plains Lab offers both urine and water testing (5)
    Energy testing methods for glyphosate toxicity:

    These methods are controversial and declared as shams by conventional medicine practitioners, but I have found them to be helpful and accurate, and will use them to evaluate my glyphosate toxicity, in addition to the more conventional hair test (above).

    Radionics, a form of energy testing available at our local Swan Valley Herbs store. It doesn’t provide the level in p.p.b. (parts per billion) like the hair, urine or blood testing; rather in relative numbers. The higher the number, the heavier the load of glyphosate.
    Body Talk and/or NAET (Nambudripad’s Allergy Elimination Techniques) and/or use muscle testing to determine if a substance is a problem, and if yes, how serious the problem might be. This too is not measured in p.p.b.; rather in whether your arm muscles are strong or weak to the substance or question asked. My acupuncturist (9) practices NAET.
    References
    Mercola: articles.mercola.com/sites/articles/archive/2019/02/04/what-is-nadph-and-nox.aspx
    Journal of Biological Physics and Chemistry: tonu.org/tonu/MyFiles/MF021-Glyphosate-V.pdf
    Wikipedia
    glycine: en.wikipedia.org/wiki/Glycine
    glyphosate: en.wikipedia.org/wiki/Glyphosate
    Detox Project:
    Five Things You Need to Know About Glyphosate Testing: detoxproject.org/5-things-you-need-to-know-about-glyphosate-testing
    Testing for pesticides in hair: detoxproject.org/testing/pesticides-in-hair
    Testing food and water: detoxproject.org/testing/glyphosate-test-home-food
    Great Pains Lab: greatplainslaboratory.com/glyphosate-test
    Sott: sott.net/article/398589-Human-hair-testing-finds-high-levels-of-glyphosate
    Natural News: naturalnews.com/050658_glyphosate_testing_Roundup_contamination_ca rcinogen.html
    Easy Health Options: easyhealthoptions.com/testing-treating-body-glyphosate/
    Steve Martinez Acupuncture, Kalispell MT: stevemartinezacupuncture.net
    Christ Masterjohn: chrismasterjohnphd.com/balancing-methionine-and-glycine-in-foods-the-database/
    Quote 23 Proven Benefits of Glycine Supplements + Glycine Foods
    By Joe Cohen

    Glycine is a great supplement to reduce inflammation, build muscle and joint tissue, reduce wrinkles, improve your sleep, and heal your liver all in a breakfast shake.

    What is Glycine?
    Glycine is one of many amino acids that commonly comprise protein. It is the smallest of all amino acids and is incredibly important for the synthesis of other amino acids, glutathione, creatine, heme, RNA/DNA, and it can also help with the absorption of calcium in the body [1, 2].

    1) Glycine is an Anti-inflammatory
    Glycine acts directly on inflammatory cells to suppress the activation of transcription factors, the formation of free radicals, and inflammatory cytokines [3].

    Glycine reduces TNF-alpha and increases interleukin-10 [4].

    Glycine can reduce TNF-receptor I levels, and raise interferon (IFN)-gamma levels in diabetic patients [4].

    Glycine significantly inhibits NF-κB activation and IL-6 production in heart artery cells [5].

    Glycine increases the anti-inflammatory IL-10 production in toxin-induced liver injury, increasing rat survival rates [6].

    Glycine significantly improves toxin-exposed mice survival rates by lowering TLR4 and TNF-alpha and inhibiting Nf-kB [6].

    Feeding rats diets high in glycine (5%) totally prevented death after exposure to an injection of a toxin (E Coli) by blunting TNF-alpha. Whereas 50% of the control group died within 24hrs [7].

    In this same study, glycine fed rats who had liver damage and also injected with a toxin had an 83% survival rate, whereas the non-glycine control group had 0% rate of survival [7].

    Glycine plays an important role in reducing oxidative stress in the body [8].

    As a precursor to glutathione, glycine can restore previously lowered levels of glutathione [9, 10].

    Glycine is recommended to the elderly because glutathione levels naturally fall with age [11].

    2) Glycine Helps You Sleep and Function Better on Less Sleep
    Taking glycine before sleep improves sleep quality and sleep efficacy by increasing the time to fall asleep, and slow wave deep sleep [12].

    After taking glycine for sleep, the following day subjects had lessened daytime sleepiness and improved performance of memory recognition tasks [12].

    Glycine helps improve REM sleep and decrease non-REM sleep [13].

    3g Glycine given to volunteers before sleeping resulted in improvements in fatigue, ‘liveliness and peppiness’, ‘clear-headedness’ [14].

    Glycine appears to improve daytime sleepiness and fatigue induced by sleep deprivation [15].

    Glycine affects certain neuropeptides in the SCN (suprachiasmatic nucleus) in the region in the hippocampus which regulate the circadian rhythm [15].

    Specifically, glycine increases VIP, which is critical to the circadian rhythm.

    This effect on the SCN indirectly contributes to reducing sleepiness and fatigue induced by sleep restriction [15].

    3) Glycine Improves the Skin
    Glycine (through the consumption of collagen) significantly improves skin elasticity in elderly women and improved skin moisture and water loss [16, 17].

    Collagen peptide is beneficial in suppressing UV-B induced skin damage and photoaging [18].

    Women taking 2.5g of collagen peptide for 4 weeks significantly reduced eye wrinkles by 20%, with positive effects lasting after the study ended [19].

    At 8 weeks, collagen significantly improved skin content of procollagen type I by 65%, and elastin by 18%.

    Glycine increases the speed by nearly double of which skin ulcers heal [20].

    Glycine enhances wound healing in diabetic animal models [21].

    Glycine in combination with l-cysteine and dl-threonine topically applied to leg ulcerations significantly improved the degree of wound healing and decreased pain [22].

    4) Glycine Helps the Gut
    Glycine inhibits stomach acid secretion and protects against chemical and stress-induced ulcers [3].

    Glycine possesses significant anti-ulcer activity [23].

    Glycine prevents chemically induced colitis in animal models [23].

    Glycine prevents alcohol-induced stomach lesions (ex. ulcers) when used as a pretreatment in animal models [24].

    Glycine can dramatically help increase the tolerability of Aspirin in the upper GI tract [25].

    In small intestine grafts, glycine improves smooth muscle dysfunction after transplantation as well as reduces inflammation [26].

    Glycine, but not L-arginine, is able to maintain intestinal wall integrity and mucosa in cancer treatment irradiation in animal models [27].

    Glycine has protective effects against oxidative stress in intestinal cells in test tubes [28].

    5) Glycine May Help Your Thyroid
    Glycine might also increase the conversion of T4 to T3 in the liver (but this has only been studied in Trout) [29].

    6) Glycine Can Help the Brain
    Small amounts of glycine have been shown to dilate the microvessels in the brain by up to 250% [30, 31].

    In rats with alcohol poisoning, glycine was able to reduce the accumulation of cholesterol, free fatty acids, and triglycerides in blood circulation, liver, and brain. Ultimately, this decreases swelling in the brain [32].

    A shortage of glycine in the brain can negatively influence the brain neurochemistry, synthesis of collagen, RNA/DNA, porphyrins, and other important metabolites [33].

    7) Glycine Helps Mental Illnesses
    Glycine supplementation has been shown in one instance over the course of 5 years to significantly reduce symptoms of OCD and body dysmorphic disorder [34].

    Glycine has positive results when used in the treatment of obsessive-compulsive disorder in adults [35].

    Glycine supplementation significantly reduced symptoms of schizophrenia [36].

    In treatment-resistant schizophrenia glycine improved cognitive and depressive symptoms (dosed at 0.8g/kg).

    Interestingly, the group who made the most improvement were also the most deficient in glycine [37].

    Glycine helps in chronic schizophrenia by increasing NMDA-receptor-mediated neurotransmission [38].

    This effect on NMDA-receptor-mediated neurotransmission allows for glycine to work synergistically with schizophrenia medication [36].

    8) Glycine May Help Combat Depression
    Depression is associated with lower levels of blood glycine, as well as high levels of taurine [39].

    9) Glycine May Reduce Obesity
    Glycine increases adiponectin, which can help with weight loss [40].

    10-11) Glycine Helps With Diabetes and Metabolic Disorders
    Glycine helps with diabetes and metabolic disorders [2].

    Glycine intake decreases free fatty acids in blood, fat tissue cell size, and blood pressure in sucrose-fed rats [41].

    Glycine reduces glycated hemoglobin (A1C), a risk factor associated with poor blood glucose management in patients with type 2 diabetes. The dose was 5g/d [4].

    5g Glycine taken in the morning increased total insulin response in healthy first-degree relatives of Type 2 diabetes patients [42].

    Glycine stimulates the secretion of a gut hormone (glucagon) that helps insulin remove glucose from circulation [43].

    Diabetic patients have 26% lower blood glycine levels than “normal” population [44].

    Glutathione synthesis is restored in patients with uncontrolled diabetes and hyperglycemia with glycine (+cysteine) added to their diet [9].

    Glycine helps patients with oxidative stress in the development of metabolic syndrome [8].

    12) Glycine May Help Glucose Balance
    Glycine helps with lipid profiles in insulin-resistant patients (but not insulin resistance).

    Glycine can help with positive glucose management by stimulating the production of Glucagon, a hormone which helps potentiate the action of insulin [43].

    Glycine helps HIV patients restore insulin sensitivity [45].

    13) Glycine Helps Reduce Inflammation From High Fructose
    In mice fed with various types of sugar, TNF-alpha is significantly higher in mice fed fructose [46].

    Glycine has protective properties against the harms of Fructose by its ability to prevent the release of the inflammatory cytokines (TNF-α, IL-6) release with fructose exposure [47].

    14-15) Glycine Helps Your Heart and Lowers Blood Pressure
    In heart attack conditions (Post-ischaemic reperfusion) glycine can prevent the death of heart muscle cells by inhibiting mitochondrial permeability [48].

    Glycine depletion within cells during a heart attack (hypoxia/re-oxygenation) makes the heart cells more vulnerable to cell death [48].

    Glycine can lower systolic blood pressure in patients with metabolic syndrome [8, 45].

    16-18) Glycine Helps with Joints, Bones, and Muscle
    Glycine can help body composition and muscle strength in people with HIV [45].

    Glycine protects against (peptidoglycan polysaccharide-induced) arthritis [3].

    Glycine combined with green tea benefits tendon recovery processes after tendinitis by better collagen bundling organization [49].

    Glycine can potentially help in menopause because of its estrogen-like bone protective effects [50].

    Glycine plays a large role in maintaining the health of mice suffering from osteoarthritis [50].

    19) Glycine Helps the Liver
    Glycine prevents lactate dehydrogenase leakage (a cell death indicator) in rat liver cells in test tubes [51].

    In rats with alcohol poisoning, feeding glycine reduced accumulation of cholesterol, phospholipids, free fatty acids and triglycerides in blood circulation, liver, and brain, ultimately reversing liver disorder associated with fat accumulation [32].

    In rats deficient in choline and methionine, glycine supplementation prevents liver injury [52].

    Glycine reduces liver damage and decreases mortality rates in rats suffering from a serious bacterial infection (sepsis) [53].

    Glycine was able to maintain Vitamin D blood levels in animals models with induced liver disease (bile duct ligation), and also slow liver damage [54, 55]

    Supplementation of glycine for five days in animal models prior to complete or partial liver donation significantly inhibited liver injury and liver-related enzymes [56].

    Glycine maintains mitochondrial activity and bile composition in liver injury in animals [57].

    20) Glycine Slows Alcohol Absorption
    Glycine slows alcohol absorption by reducing the rate at which the stomach absorbs alcohol as well as empties into the intestine [58].

    Blood alcohol levels were significantly lower in individuals who had consumed glycine prior to intoxication over controls who had not [59].

    21) Glycine Helps the Kidneys
    Kidney tubes (proximal tubules) are resistant to oxygen deprivation damage if glycine is present in the test tube [60].

    22) Glycine Prevents Cavities
    In rat models, supplementation with 4% glycine caused a 65.7% reduction of cavity occurrence [23].

    23) Glycine Can Help Stroke Patients
    In ischemic stroke patients, taking glycine 1 – 2g/day normalized autoantibodies, reduced glutamate and aspartate levels, increased GABA concentrations, and reduces lipid peroxidation [61].

    Those who consume regularly low doses of glycine actually reduce damage in future strokes [61].

    The glycine treatment at the dose of 1 – 2g/day was accompanied by a tendency to a decreased risk of dying over 30-days [61].

    500mg/kg glycine combined with 500mg/kg Piracetam improved cognitive impairments and promoted recovery in the prefrontal cortex in animals with a stroke [62].

    Note: Some of the scientific sources obtained for this article was found on Vladamir Heiskanen’s blog.

    Dietary requirements
    Glycine is sometimes called a semi-essential nutrient because it is both made by the body and obtained from food, although the combination of the two is not always enough to supply various tissues, bone, muscle, and skin with what is needed.

    The average person usually can make roughly 3g of glycine, and usually consume 1.5 – 3.0 g from food, making their daily intake from roughly 4.5 – 6g [63].

    Clinical and nutritional studies over twenty years indicate that the amount of glycine available in humans is not enough to meet metabolic needs and that a dietary supplement is appropriate (see the body of study) [63].

    One study suggests that humans may fall significantly short of the amount needed for all metabolic uses – by about 10 g per day for a 70 kg (154 lbs) human [63].

    How Much Glycine Do I Take?
    I try to get in about 3 – 5g of extra glycine daily, either from pure Glycine Powder or from 20g of Collagen.

    Side Effects of Glycine
    Slight sedation is a possible side effect of taking Glycine [61]. This is often why it is recommended to take in the evening.

    Potential Downsides of Glycine
    In a Japanese study of nearly 30,000 patients, the risk of dying after stroke may be increased by meat consumption. The scientists suggest it is the increase in glutamic acid and glycine which cause this correlation [64].

    Glycine is not recommended to take while suffering from diarrhea. It may worsen the condition and lead to poor rehydration [65].

    Top Foods with The Highest Glycine Content
    You can get a good amount of glycine from glycine, collagen or gelatin.

    A list of foods high with glycine:

    Gelatin
    Whitefish
    Soy Protein Isolate
    Chicken
    Turkey
    Pork
    Beef
    Collagen contains 22 – 30% glycine. Adding 1 – 2 tbsp. a day to a breakfast smoothie will give you an additional 2.5 – 3.5g glycine per Tbls.

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    Default Re: Glyphosate remediation

    "Correlation does not mean causation" is the mantra that is used to discount all anecdotal evidence (such as with all the accounts from parents that vaccination was associated with the injuries to children)

    Jim Humble and MMS (chlorine dioxide) has been discussed in other MMS related forum threads

    This is a very coherent discussion of Chlorine Dioxide and why it may be effective with glyphosate?



    Kerri Rivera has offered a free book Healing the Symptoms Known as Autism
    Last edited by Delight; 22nd May 2019 at 19:21.

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    Default Re: Glyphosate remediation

    In the previous video, mention was made that glyphosate may remain in soil for years.
    Biochar can remediate glyphosate in the soil.
    Charcoal can be used as a standard additive to animal feed to remove toxins, including glyphosate.....

    Quote The use of biochar in cattle farming

    by Achim Gerlach and Hans-Peter Schmidt
    90% of the biochar produced in Europe is used in livestock farming. Whether mixed with feed, added to litter or used in the treatment of slurry, the positive effect of biochar very quickly becomes apparent. The health – and consequently the well-being – of the livestock improve within just a short space of time. As regards nasty smells and nutrient losses, the use of biochar could even herald a new age of livestock farming, closing agricultural cycles of organic matter.

    Introduction
    Hormonal, chelating, antibiotic, teratogenic, carcinogenic and neural effects are the main symptoms of the cattle diseases, with which I am faced in my daily practice as a vet. The productivity of cows and thus of production units are greatly dependent on the proper functioning of the gastrointestinal tract. This is the reason why diseases of the digestive tract and the corresponding treatment strategies play a key role in commercial livestock farming. Maintaining “eubiosis” (host and microflora living together in symbiosis) in the gastrointestinal tract of animals is becoming increasingly difficult, as more and more farms (i) specialise in either crop farming or livestock farming, and (ii) merge together to form increasingly larger units. The result is that feedstuff can no longer be “home-grown” in sufficient quantities and quality and instead has to be purchased from outside. More often than not, farmers are no longer in a position to assess the quality of such feedstuff (purchase is based on trust).
    Directly linked to this problematic situation is the appearance of chronic botulism that reached disturbing levels in herds of cattle over the last few years (Krüger et al. 2012, Böhnel u. Gessler 2012). Affecting cattle, the disease – a toxic infection – is caused by clostridium botulinum toxins and is leading to significant direct and indirect losses in livestock farming. In her search for the main factor(s) influencing the emergence of this new phenotype, Krüger (2012) took a close look at the role played by glyphosate, a broad-spectrum systemic herbicide, and AMPA, its main metabolite. Her research revealed major amounts of glyphosate notably in the urine of dairy cows (up to 164 micrograms / l in Germany and up to 138 micrograms / l in Denmark, on average 20-50 micrograms / l) but also in rumen fluid (0.04 to 122 micrograms / l). Glyphosate was also found in human urine (up to 2.8 micrograms / l), although to a much lesser degree (see: Herbicides found in Humane Urine). Moreover glyphosate has also been detected in digestate from biogas plants and in different animal feeds, often in alarming concentrations. The fact that glyphosate has antibiotic effects is incidentally well-known to the producers of the herbicide, with Monsanto even filing an application for it to be patented as such (US-Patent 7,771,736, EP0001017636). When glyphosate gets into the digestive tract of animals and humans, it causes detectable changes in the gastrointestinal microbiota.
    A good prophylactic, metaphylactic and therapeutic possibility of binding botulinum toxin and other toxins formed by clostridia, as well as the herbicide glyphosate increasingly detected in feedstuff, in the gastrointestinal tract of cattle seems to be the administration of biochar.
    .

    The effect of activated carbon and biochar in feeding
    For some hundred years, research into activated carbon has been showing effective ways of adsorbing pathogenic clostridial toxins such as C. tetani und C. botulinum (Kranich 1920, Luder 1947, Starkenstein 1915). Wang et al (2010) have shown that biochar has good sorption qualities with regard to the hydrophobic herbicide terbuthylazine and underline the important role it can play in protecting ground water. Graber et al. (2011) studied the binding qualities of the model herbicides S-Metolachlor and Sulfentraton on biochars with different surface sizes. Graber (2012) confirmed that biochar can adsorb glyphosate. The use of carbon gained from pyrolysis for feeding purposes has been known for a long time and is recommended in Germany. Mangold (1936) presented a comprehensive study on the effects of charcoal in feeding animals, concluding that “the prophylactic and therapeutic effect of charcoal against diarrhoeal symptoms attributable to infections or the type of feeding is known. In this sense, adding charcoal to the feed of young animals would seem a good preventive measure.”

    Activated carbon = biochar?
    Generally speaking, all activated carbons are originally biochars. Active carbons are however “activated” using acids or hydroxides or 900°C water steam. In doing so, their specific surface area increases from app. 300 m2/g to over 1000 m2/g. Activated carbon is 5 – 10 times more expensive than simple biochar, so it is possible to use 2-3 times the amount of biochar to achieve the same result – whether with regard to digestion in cattle or in a sewage treatment plant. As activated carbon is for the most part produced without adequate controls in South-East Asia or South America, the eco-balance often leaves a lot to be desired. Biochar by contrast is produced from controlled, locally grown raw materials using controlled production methods. There is no real difficulty involved in producing activated carbon from biochar.

    Volkmann (1935) describes an efficient reduction in excreted oocysts through adding charcoal to the food of pets with coccidiosis or coccidial infections.
    Haring (1937) recommends mixing charcoal into cattle feed, while Barth and Zucker (1955) were not able to establish any negative growth effects in poultry when the level of added charcoal was kept at around 1%.
    From an international perspective, we are currently seeing repeated reports on the advantages of mixing biochar into animal feed:

    • It’s used with goats in North Vietnam. Growth rates improved here when feed included 0.5-1g of bamboo coal / kg per day (DoThiThanVan, 2006).
    • Kana et al. (2011) have shown that 0.2-0.6% corncob charcoal added to chicken feed results in significant weight increases.
    • Iwase et al. (1990) have demonstrated – in an experimental environment – the storage effect of activated carbon in rumen acidosis in Holstein bulls.
    • Leng et al. (2012) proved that methane formation could be reduced by 12.7% (10%) when 1% (0.5%) char is added to an artificial rumen system.

    The effects of biochar are based on the following mechanisms: adsorption, coadsorption, competition, chemisorption, adsorption followed by a chemical reaction, desorption. From a toxicology perspective, classifiable distinctions need to be made to the time-dependent processes of adsorption, distribution, biotransformation and excretion of the toxic substances in the digestive tract of animals.
    With regard to the specific mechanisms, more detailed research is urgently needed.
    Schirrmann (1984) describes the effect of activated carbon on bacteria and their toxins in the gastrointestinal tract:

    1. Adsorption of proteins, amines, amino-acids
    2. Adsorption of digestive tract enzymes, as well as concentration of bacterial exoenzymes in the activated carbon
    3. Adsorption, via chemotaxis, of mobile germs disposing of special attachment mechanisms.

    Of particular importance is the specific colonisation of the char with gram-negative germs with increased metabolic activity. This results on the one hand in a decrease in endotoxins needing to be resorbed and on the other hand in the adsorption of the toxins in the char.
    Ariens and Lambrecht (1985) describe the advantages of activated carbon, stating that it is non-toxic, quickly available, has an unlimited shelf-life, is effective in the gastrointestinal tract, and is effective against already absorbed toxins and mineral oil products.
    One major advantage in the use of biochar is to be found in its “enteral dialysis” property, i.e. already absorbed lipophilic toxins can be removed from blood plasma by the char, as the adsorption power of the huge surface area of char interacts with the beneficial permeability properties of the intestine. Adsorption applies to both lipophilic and hydrophilic substances. The speed at which adsorption takes place is dependent on the size of the activated carbon’s pores. What we are thus seeing is the emergence of a genuine alternative to the established medical therapies – peritoneal dialysis, haemodialysis or haemoperfusion.
    Via manure and slurry, the biochar mixed with the feed is returned to the soil, closing the organic cycle. The fact that biochar returned to the soil this way can be of interest for agriculture was already described by Perotti back in 1935. For him, the presence of biochar in the soil meant an improvement in its microbiological properties and a better supply of chlorophyll for the plants.
    In his view, the benefits of biochar were as follows:

    1. Moisture retention
    2. Increased adsorption of ammonium salts
    3. Decreased dispersion of nitrates
    4. Adsorption of microbial metabolites

    Söhngen (1913) sees the formation of ammonium carbonate combined with the char adsorption as playing a key role in the longer-term development of rich cultures of bacteria which find their way into their surroundings through desorption. In a slightly acidic environment in particular, this process of alkalization through the adsorption of carbon only takes place slowly. Schirrmann (1984) reports that the oxidisation reactions on activated carbon can be improved through increasing the nitrogen content. Nagel (1990) studied activated carbon populated by bacteria, without being able to find any efficient method of desorbing adherent bacteria. Proving the existence of bacteria via excreted metabolites was not possible, and the only way of determining adherent cell counts was through the use of a gamma-ray marker (Fe-59).
    .

    The use of biochar in cattle farming
    Biochar was administered at a dosage of 200-400g per cow and day in the farms I myself am responsible for, on the basis of studies by Feldmann (1992), who conducted in vitro experiments with activated carbon. But the adsorption capabilities of chars gained by pyrolysis show major variations. Chars produced from wood and plants are unable to exceed the level of the so-called “blood carbon” which contains a further adsorbent, bentonite, and is activated at higher temperatures. Feldmann (1992) studied the effects of activated carbon on fermentation processes in rumen fluid (in vitro), detecting an up to 25% increase in the pH-level, an up to 32% decrease in the redox potential, a reduction in the concentration of volatile fatty acids (though the production rate remained constant), and a rising adsorption rate with increasing chain lengths of the volatile fatty acids. These effects were dependent on the char dosage.
    The use of biochar as a feed ingredient is subject to strict food quality rules under EC Regulation 178/2002 and to the strict regulations for organic livestock feed under EC Regulation 834/2007. In particular, the levels of heavy metals, dibenzodioxins and dibenzofurans play an important role as limiting factors, whereby biochar produced under the European Biochar Certificate meets all the animal feed threshold values. In our own tests, the only biochar used was inert biochar (carbo ligni) made by means of a technical pyrolysis using the so-called “Schottdorf reactor”. The safety of biochar as a feed additive has been certified by Biocheck, a laboratory for veterinary diagnostics and environmental hygiene. Preliminary tests on the adsorption capacity of the biochar used were performed by the Central Laboratory of German Pharmacists, comparing it with commercially available activated medical charcoal using the phenazone adsorption test. The adsorption capacity of 16.7 g phenazone/100g dried biochar is about one-third of the levels reached by medical charcoals of 40g phenazone/100g charcoal. These results confirm the findings of Luder, W. (1947), who studied the adsorption capacity of carbo ligni and carbo adsorbens and came up with a ratio of 1:3-4.
    Now that biochar can be produced economically (i.e. it is available at low cost and high quality), the long-known benefits of feeding biochar can be feasibly put into practice.



    Practical use of biochar in feeding cattle
    21 farm managers, each with an average herd of 150 cows, gave their impressions of the effects they had observed during and after the administration of biochar. It should be noted that biochar administered as treatment for dysbiosis was concomitantly supported in about 1/3 of the farms by sauerkraut brine (acetylcholine, lactobacilli, enterococci, B-vitamins, vitamin C).
    Observations of initial effects (1 – 4 weeks after starting biochar administration):

    • Generally improved health and appearance
    • Improved vitality
    • Improved udder health
    • Decreased cell counts in the milk (interrupting the administration of biochar leads to higher cell counts and a drop in performance)
    • Minimisation of hoof problems
    • Stabilisation of post-partum health
    • Reduced diarrhoea within 1-2 days, faeces subsequently generally more solid
    • Decline in the mortality rate
    • Increase in milk protein and/or fat
    • Combining biochar and sauerkraut brine has proved worthwhile
    • Marked improvement of slurry viscosity, with less stirring needed and less scum on the surface
    • Slurry not smelling as bad as it used to

    Preliminary tests on the slurry show that adding biochar via the gastrointestinal tract or via direct application:

    • Increased ammonium nitrogen
    • Reduced nitrate and nitrite



    Summary and conclusions
    The use of biochar in livestock farming offers solutions to the increasingly complex problems of modern-day farming, the result of a combination of profit maximisation and disrespect for the physiological needs of the animals. The adsorption qualities of biochar permit a wide range of toxic substances to be bound in the gastrointestinal tract. They also lead to the detoxification of already resorbed toxins (in particular lipophilic toxins) in the plasma via “enteral dialysis”. The oxidation and deamination of biogenic amines also play a particularly stabilising role in the intestines. Dysbiosis can be very efficiently and positively influenced by biochar, and eubiosis can be maintained much longer despite environmental fluctuations in the digestive tract.
    A clear separation of the impact in the pro- or metaphylactic field and the therapeutic approach is desirable in theory, though in practice these effects are overlapping. In cases of acute intoxication, the parallel administration of saline laxatives is recommended (Wiechowski 1914).
    One current problem affecting Schleswig-Holstein and Lower Saxony in particular is the high level of nitrate pollution in drinking water, the result of intensive farming. The scientific methods for reducing nitrates in the soil have been known for more than a century. Reductions can be achieved by the intelligent use of commercial fertilisers based on biochar. Reports in this area have been published by Sommer (2005). Similarly, the changed economic conditions under which farms operate mean that what is now needed is a re-assessment of certain practices from an epidemiological perspective. These include the disposal of placentas via the slurry system and the widespread use of bone meal as a fertiliser especially on account of increased maize production. One option available for minimising expected epidemiological and drinking water problems involves the inclusion of inert biochar in agricultural cycles of organic matter.
    Also necessary are tests on the biochar used, making sure that it complies with the structural, chemical, physical and biological requirements of the European Biochar Certificate (EBC). This is the only way to achieve a transferability of the results gained in the use of different chars to other studies.



    Achim Gerlach is a vet working for the Schleswig Holsteinschen Landkreis Dithmarschen and is probably the expert with the most experience in Europe on the administration of biochar in livestock feed. Should readers wish to directly contact the author, please just drop us a line.

    .



    Literatur
    Krüger, Große-Herrentey, Schrödel, Gerlach Rodloff: Anaerobe, 18 (2012) S.221-223
    Böhnel u. Gessler: Tierärztliche Umschau, 67, 7 (2012)
    Krüger, M.: Vortrag Bad Fallingbostel 2012
    Kranich, J.: Tierärztliche Rundschau (1920)S.610-612
    Luder, W.: Unters. ü. d. Bakt. Adsorption durch Holzkohle – Diss. 1947 Univ. Bern
    Mangold, E.: Der Forschungsdienst (1936) Bd.1 S.862-867 Hrsg: Reichsarbeitsgemeinschaften d. Landwirtschaftswissenschaft
    Volkmann, A.: Beh. vers. der Kaninchen- bzw. Katzencoccidiose… -Diss. Univ. Leipzig 1935
    Haring,F.:Mitt. f. d. Landwirtschaft 52 (1937)S.308-309 Hrsg: Reichsnährstand
    Barth und Zucker: Z.f. Tierernährung und Futtermittelkunde 10 (1955) S.300-307
    DoThiThanVan, Nguyen Thi Mui, Inger Ledin: Animal Feed Science and Technology 130 (2006) S.242-256
    Kana, Teguia, Mungfu, Tchoumboue: Trop. Anim. Health Prod. (2011) S.51-56
    Iwase, Matui, Hoshi, Motoyoshi: XVI Congresso Mundial DE BUIATRIA, Salvador –Brasil,(1990)S.436-440
    Leng, Inthapanya u. Preston: Biochar lowers net methan production from rumen fluid in vitro
    http:/Irrd.cipav.org/Irrd24/6/sang24103.htm (26.6.12 -22.06)
    Schirrmann,U.: Aktivkohle u. ihre Wirkung auf Bakterien… Diss. 1984 TU München
    Ariens u. Lambrecht: Schriftenreihe d. Bundesapotherkenkammer zur wiss. Fortbildung,Meran 1985, 20. Intern. Fortbildungskurs f.prakt.u. wiss. Pharmazie, S.
    Perotti,R.:Bolletino delle Sezione Italiana di Microbiologia 7 (1935)S.449-452
    Söhngen, N.L.: Centralblatt f. Bakt., Parasitenkunde u. Inf. Krankheiten 38 (1913)S.621-646
    Nagel, S.: Unters.z. bakt. besiedelter Aktivkohle, Diss. 1990 Univ.Stuttgart
    Feldmann, M.: Auswirkungen von Aktivkohle auf Fermentationvorgänge im Pansensaft des Rindes (in vitro), Diss. 1992, Tierärztliche Hochschule Hannover
    Starkenstein, E.: Feldärztliche Beilage zur Münch.med.Wochenschr. (1915) S.27-29
    Hellerich,B.:Diss.TiHo( 2008) Zusammenhänge zwischen Fütterung, Haltung sowie Managementaspekten und der Tiergesundheit in Milchviehbetrieben.
    Dechow,CD; Smith,EA;Goodling,RC: The effect of management systems on mortality and other welfare indicators in Pennsylvania dairy-herds. In:Animal Welfare 2011;20:145-158
    Wang,Linn,Hou,Richardson,Yan: J. Soils Sediments (2010) 10:283-289
    Graber,Tsechansky,Gerstl,Lew:Soil Sci.Soc.of Am.J. (2011) 75:1365-1373
    Graber (2012)ers.Mitteilung
    Eisenberg,Ph: Z.bl.f.Bakt.,Parasit.kde u. Inf.krakh. (1914),1.Abt. Bd. 81S.72-104
    Wiechowski,W.harmakologische Grundlagen einer therapeutischen Verwendung von Kohle.Dt
    Kongreß f. Innere Medizin, Wiesbaden (1914)

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    Default Re: Glyphosate remediation

    The synergy between aluminum and glyphosate is deadly

    Quote July 2016
    Clinical Insights from the Sophia Health Institute
    by Dietrich Klinghardt, MD, PhD, and Dr. Christine Schaffner


    Aluminum and Glyphosate
    There is growing awareness of the increasing environmental exposure of aluminum and glyphosate, the active ingredient in the herbicide Roundup.

    We have been tracking both of these toxicants in our patients and use several treatment strategies to decrease the body burden of both of these harmful substances.

    Dr. Stephanie Seneff first opened our eyes to the biological impact of glyphosate. Her recent paper "Aluminum and Glyphosate Can Synergistically Induce Pineal Gland Pathology: Connection to Gut Dysbiosis and Neurological Disease" demonstrates the synergy of aluminum and glyphosate.1

    In summary, through several mechanisms glyphosate increases the uptake of aluminum in the gut while blocking the uptake of a variety of needed trace minerals. The increased body burden of aluminum damages the pineal gland. Both aluminum and glyphosate disrupt the CYP450 enzymes, which have a role in melatonin production. In addition, glyphosate disrupts the production of tryptophan – a precursor to melatonin – by our beneficial bowel microbes. Both toxicants impair the body's production of melatonin. We just reviewed how sleep is imperative for the glymphatic system. Disrupted melatonin production directly impairs the brain's ability to detoxify.

    It is difficult to demonstrate the body burden of aluminum using a traditional urine challenge test. Aluminum is firmly bound to tissue proteins and very hard to mobilize with any type of challenge test. We recently started using the OligoScan, a device that uses a technology called spectrophotometry to determine tissue trace element and heavy metal levels. The majority of our patients have overwhelmingly elevated aluminum. Aluminum is today the most prevalent toxic metal in our patients – ahead of lead, mercury, nickel, and tin.

    It is also challenging to demonstrate the body burden of glyphosate. We look at PON1 gene status and exposure history to determine necessity of treatment. We support PON1 epigenetically with antioxidants such as açai, pomegranate, vitamin C, selenium, and vitamin E. We also use low-dose immunotherapy to facilitate the removal of glyphosate and other herbicides that typically are in the same cocktail. When we split-sampled patients' urine in the past, typically the US labs did not find any glyphosate, while the German labs found significantly elevated levels in the same urine. A new US-based urine glyphosate test is now available that we do not have clinical experience with yet.

    Our current aluminum detoxification strategies include silica-based products. We commonly use liposomal silica, horsetail, and a silica-based binder called Enterosgel to decrease aluminum in our patients. The US-trained neurologist Margaritha Griess-Brisson (living in the UK) found that a cilantro tincture given 3 times per day combined with an ionic footbath used twice weekly increased the elimination of all toxic metals, especially the excretion of aluminum. Y. Omura, MD, also found that cilantro was effective in removing lead, mercury, and aluminum (study on mice).

    Case Study: 28-year-old female, chronic fatigue, constipation, nausea, head pain, pressure .pdf

    Case Study
    J.F. was an 8-year-old autistic boy who was mute. He had been through the biomedical approach for years and had improved largely. What was not addressed in his treatment was the intrauterine exposure to Lyme and glyphosate and the early exposure to aluminum (ambient air, vaccines) and ethylmercury. We added the strategies for these issues, included LDI treatment for mercury, Lyme, glyphosate, and aluminum. After a few initial crises, he started to make one-syllable words; within a few weeks, two-syllable words; and after 9 months (of the added treatment), he was completely age-appropriately fluent in English and near neurotypical.

    Conclusion
    Microbes evolve, toxins used in our environment have changed – and exposures to them, and with them illnesses evolve. What we see today in our medical offices is almost completely different from what Dr. Klinghardt saw when he started seeing patients 41 years ago. Lab methods are often hopelessly behind the times and we, the frontline physicians, have often to rely on other tools to help diagnose our clients. The current plague of Lyme disease, retroviral infections, and environmental toxins affecting us were not discovered in a university lab. These most pressing issues were discovered by us, the people. In this article, we point toward several illness-causing issues that are relevant to almost every person we see in the office. In a future article, we may highlight the other big one: exposure to microwaves and adverse electromagnetic fields and what we can do about it. When we know what is underneath our illnesses and causing them, we can still protect and heal others and ourselves and have fulfilling, joyful lives.

    Notes
    1. Seneff S, Swanson N, Li C. Aluminum and glyphosate can synergistically induce pineal gland pathology: connection to gut dysbiosis and neurological disease. Agric Sci. 2015;6:42–70.

    Dietrich Klinghardt, MD, PhDDietrich Klinghardt, MD, PhD, was born, raised and educated in West Germany, where he graduated from Freiburg Medical School/Albert Ludwigs University in 1975. He also studied psychology and completed a 3-year research project/PhD in angiology. He is internationally known for his successful treatment of chronic pain and illness. Dr. Klinghardt combines nonsurgical orthopedic medicine with immunology, endocrinology, toxicology, neural therapy, hypnotherapy, and energy psychology. He has been in practice for over 40 years and has been a pioneer in the diagnosis and treatment of Lyme disease, applying his 5 Levels of Healing model. Dr. Klinghardt founded Sophia Health Institute in Woodinville, Washington, where he sees patients.

    Dr Christine Schaffner

    Dr. Christine Schaffner is a board-certified naturopathic physician who graduated from Bastyr University. She completed her undergraduate studies in pre-medicine and psychology at the University of Virginia in Charlottesville, Virginia. Dr. Schaffner specializes in the treatment of chronic illness and is the clinic director of Sophia Health Institute in Woodinville, Washington.
    Quote Recovery Methods for a Brain with Aluminum and Glyphosate Exposure

    Please see my previous post on the importance of understanding the pathophysiology of Glyphosate, better known as Monsanto’s RoundUp. The first part is entitled Monsanto’s Round Up and Aluminum Now Linked to Autism, Alzheimer’s, Gut Dysbiosis and Pineal Gland Calcification. This is the second part with solutions.

    This pesticide which has far reaching effects, has been shown to bind up aluminum and bypass the gut barrier, decimating all immunity and amino acids made by our beneficial gut bacteria.

    By popular demand, I will be discussing how to detoxify from aluminum and pesticide exposure. Together, heavy metals like aluminum and Glyphosate have synergistically devastating effects. My previous blog post showed that pesticides provide an easy passage to aluminum where the bloodstream filters it quickly through the brain and the kidneys. The issue with this is that the pineal gland, which sits inside the optic chiasma in the brain, is not protected by the blood brain barrier and gets the brunt of unfiltered blood. If it is exposed to aluminum and/or pesticides, it is at a higher risk to accumulate these toxic substances. The repercussions of this are thought to be far reaching but have not been substantially researched.

    Glyphosate

    Glyphosate, or RoundUp, is the best selling pesticide in history since going to market in 1974. Nearly 90% of all corn, soy and cotton are aerially sprayed with this toxic pesticide. A recent study showed Glyphosate was found 700 times higher than the Environmental Protection Agency’s legal limit in the breast milk of mothers. Another study found that Americans have ten times more Glyphosate in their urine than their European counterparts. Seeing as how recent studies have shown the devastating effects of Glyphosate on our gut bacteria, which helps to sustain mood, immunity, and overall wellbeing, all of this is quite concerning.

    Aluminum

    Specifically, Dr Seneff’s work has shown how aluminum works with Glyphosate to avoid our body’s defenses as it enters the body. Heavy metals in general have known negative effects on the body. Both mercury and aluminum are highly neurotoxic and can accumulate in the brain. Multiple studies have shown a direct link to aluminum toxicity and Alzheimers. Now Dr Seneff’s work has shown correlation to aluminum and pineal gland calcification, as nearly all Alzheimers patients have a calcified pineal gland. Both mercury and aluminum have vague toxic profiles including emotional instability and lability, lethargy, depression, anxiety and attention problems. Aluminum alone causes flatulence, headaches, colic, dryness of the skin, tendency to come down with colds/flus, and heartburn.

    An average adult in the United States eats about 7–9 mg of aluminum per day in their food. Approximately 95% of an aluminum load becomes bound to transferrin and albumin intravascularly and is then eliminated via the kidneys. In healthy subjects, only 0.3% of orally administered aluminum is absorbed via the gastrointestinal (GI) tract, however, this statistic is not taking into account that the bioavailability becomes much higher when bound to Glyphosate. Only when the GI barrier is bypassed, such as by intravenous infusion (think vaccines), when bound to pesticides, or if the kidneys are diseased, does aluminum have the potential to accumulate. As an example, with intravenously infused aluminum, 40% is retained in adults and up to 75% is retained in babies.

    A calcified pineal gland is also linked to high fluoride consumption, which is found added to tap water, medications and toothpaste.

    For more information, please revisit my blog post concerning the synergistic effects of Glyphosate and aluminum.

    How To Detox From Heavy Metals and Glyphosate

    I make an excellent heavy metal detox which you can check out in the Dr Jess store, but for now, lets investigate what you can do to actively clear your pineal gland and the gut of these toxic substances.

    Eat organic-One Swedish study showed a family who tested positive for glyphosate at the beginning of the study. They all ate organic for the next three weeks and their urinary excretion of Glyphosate dropped significantly. Avoiding GMO food, which has a considerably higher amount of pesticide used on it, avoiding soy, corn and wheat, as well as educating yourself on foods that help to eliminate these toxins by providing necessary cofactors and nutrients.
    Eat sulfur rich foods-sulfur is one of the nutrients disrupted by Glyphosate and proven by the Seneff study. This includes brussels sprouts, broccoli, cabbage, legumes, bok chop, garlic, cauliflower, kale, radish and watercress. The high sulfur content of these foods provide necessary cofactors to make glutathione, the master antioxidant of the body. It is also used in step one and two detoxification in the liver.
    Take probiotics-since glyphosate and heavy metals can help decimate the beneficial bacteria in the gut, it makes sense that exogenously replacing these colonies with probiotics would help to rid the body of toxins. Our gut bacteria are life and provide necessary amino acids, building blocks and cofactors for immunity and stable moods, If our guts are not happy, then our brains are likely unhappy too.
    Silica-Research published in 2013 showed that drinking up to one liter of a silicon-rich mineral water daily for 12 weeks effectively excreted aluminum via the urine, without detrimental effects on essential metals such as iron and copper. According to the authors: “We have provided preliminary evidence that over 12 weeks of silicon-rich mineral water therapy the body burden of aluminum fell in individuals with Alzheimer’s disease and, concomitantly, cognitive performance showed clinically relevant improvements in at least 3 out of 15 individuals.” Think Fiji water.
    Humic and fulvic acid-Found in rich supply in Shilajit and in the soil, these two minerals have been shown to remove glyphosate from the villi of the intestines in third party studies. They also help to modulate the immune system by working in the gastrointestinal tract.
    Melatonin: Research shows that melatonin has a metal binding role and is a useful supplement in the treatment of neurological disorders in which oxidative stress is involved, which includes Alzheimer’s. Melatonin can travel freely across all cellular barriers, facilitating the removal of toxic metals such as aluminum. It also appears to suppress the oxidative activity of aluminum in your brain. Melatonin is also one of the hormones that is blocked by Glyphosate exposure, so exogenous support is quite beneficial to rid yourself of this toxin. New research shows melatonin also has anti cancer properties.
    Raise your Glutathione- Your body synthesizes this master antioxidant from three amino acids: “cysteine, glutamate, and glycine. Raw fruits and vegetables, particularly avocado, asparagus, grapefruit, strawberries, orange, tomato, cantaloupe, broccoli, okra, peach, zucchini, and spinach are rich in the precursors glutamate and glycine. Dietary sources of cysteine include eggs, meat, red peppers, garlic, onions, Brussels sprouts, and wheat germ.” Other helpful treatments for improved glutathione metabolism are exercise and the proper vitamin D levels. (I like my patents around 50).
    Chlorella-this ancient blue green algae contains nearly all essential amino acids and is jam packed with protein. It not only works in unison with cilantro, but can remove the heavy metals from the body through urinary excretion.
    Cilantro-Cilantro works well with chlorella to chelate, or bind, up heavy metals to excrete them. The issue with cilantro alone is that although it chelates heavy metals, it does not remove them in the urine. This means they can recirculate to deposit elsewhere in the body. This is why I recommend that you always take cilantro with chlorella as chlorella does remove the metals through kidney excretion. In one study, in Japan in the Journal of Ethnopharmacology, researchers found that cilantro was able to chelate aluminum. “After the 25-day trial period, the mice were checked for lead. The results showed that both the cilantro and the DMSA had “significantly decreased lead deposition in the femur and severe lead-induced injury in the kidneys.” Moreover, the cilantro increased the urinary excretion of delta-aminolevulinic acid (ALA), which is known to increase with lead intake.”
    Iodine/Kelp-iodine dispels fluoride and bromide as well as heavy metals from the body. Iodine deficiency has come into question for a number of cancers including breast, thyroid and prostate cancer.
    Avoiding fluoride/Buy a water filter-a Berkley runs around $200-300 and you can order fluoride filters specifically to remove this toxic halide from your water supply. Check them out at www.berkey.com. I do not think its advantageous for anyone to be drinking out of the tap these days.
    Third Eye Meditation-this meditation involves staring up at the point in between the eyes with your eyes closed. This can send awareness and blood supply to the area.
    Epsom salt baths-provide detox baths for heavy metals. Magnesium stores are depleted during heavy metal toxicity and detox. The body uses magnesium in over 300 processes in the body and heavy metal detox is one of them! Epsom salt is magnesium sulfate and sitting in a bath for approximately 30 minutes is a great way to replenish these stores.
    MSM supplementation-MSM is a form of sulfur which acts on cell membranes and can help to replenish sulfur stores that are disrupted by Glyphosate exposure. It has also been known to help mercury toxicity.
    N-acetyl L-cysteine (NAC) may also be useful. NAC is the rate-limiting nutrient for the formation of the master antioxidant glutathione. So replacing these stores can help boost glutathione levels in the body.
    Curcumin- Research suggests that curcumin has a protective effect against aluminum-induced damage by modulating the extent of oxidative stress. Studies have shown that curcumin can help improve memory in Alzheimer’s patients. There are some contraindications that curcumin is not recommended if you have biliary tract obstruction (as it stimulates bile secretion), gallstones, or on a blood thinner. (curcumin is a natural blood thinner).
    Other supplements that may help include: Gotu kola, boron, coconut oil, beets, apple cider vinegar, ginseng, bentonite clay (avoid contamination with heavy metals), milk thistle, dandelion root and burdock root.
    CHELATION-This is the most effective way to remove all heavy metals. It can bind up other beneficial nutrients that you wouldn’t necessarily want removed. Chelation can also be hard on the kidneys. However, I have witnessed amazing results with IV chelation with EDTA, DMSO or DMPS concerning heavy metal toxicity and heart disease.
    You can heal!

    Much love
    Dr Jess

    REFERENCES:
    httpss://www.ncbi.nlm.nih.gov/pubmed/11535365
    Séralini G-E, Clair E, Mesnage R, Gress S, Defarge N, 1, Malatesta M, Hennequin D, Spiroux de Vendômois J. Republished study: long-term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Environmental Sciences Europe 2014, 26:14.
    httpss://www.ncbi.nlm.nih.gov/pmc/articles/PMC1130580/
    [2] Wolff J (1964) Transport of iodide and other anions in the thyroid gland. Physiol Rev 44:45-90
    Quote Are you detoxing with the correct binders?

    Intestinal binders are a crucial part of any detox protocol. When the liver processes toxins, they get excreted through bile and into the small intestine. If the toxins are not bound to anything, most of them will get reabsorbed in the gut. This is called enterohepatic recirculation. Binders can be used to bind to the toxins so that they can pass all the way through the digestive tract to be eliminated.

    There are a variety of binders available. Different binders have affinities for different toxins based on the net charge and different molecular bonds. The following are some of the most commonly used binders:

    Chlorella: Chlorella is algae that has a high affinity for heavy metals, but also volatile organic compounds (VOCs), pesticides, herbicides, and mycotoxins. Because chlorella is a living organism, it has evolved to bind only to toxic metals, not essential minerals. For this reason, it can be used long term with no risk of nutritional deficiency over time. It is also a good idea to take chlorella before eating any higher mercury fish, such as tuna or swordfish.

    Chlorella is algae that has a high affinity for heavy metals, but also volatile organic compounds (VOCs), pesticides, herbicides, and mycotoxins. Because chlorella is a living organism, it has evolved to bind only to toxic metals, not essential minerals. For this reason, it can be used long term with no risk of nutritional deficiency over time. It is also a good idea to take chlorella before eating any higher mercury fish, such as tuna or swordfish.

    Other Algaes: Ecklonia cava and spirulina have similar properties as chlorella.

    Charcoal: A very broad-spectrum binder that will bind a little bit of everything. This means it will bind toxins, as well as vitamins and minerals. For this reason, it is best used for acute situations, not long term.

    Clays: Zeolite, bentonite, and pyrophyllite clays fall somewhere in between chlorella and charcoal. Clays are more selective to binding toxins than charcoal, but can still bind to nutrients. They are most commonly used for binding to biotoxins from mold and other microbes but can bind to other toxins as well. Clays are usually used for weeks to months at a time.

    Enterosgel: A silica-based gel that has a high affinity for aluminum. It is also good for binding to gut endotoxins and is marketed to be used for food poisoning. It has a low affinity for vitamins and minerals.

    Silica-Rich Mineral Waters: Silica easily obtained through mineral water can bind to aluminum.

    Biosil and Other Silica Products: Bind mostly to aluminum, but also other trivalent metals like thallium and tin.

    Cholestyramine and Welchol: These are prescription medications that were developed to bind cholesterol. They are commonly used to bind to mycotoxins, but they can decrease absorption of fat-soluble vitamins over time.

    Chitosan: A compound derived from crustaceans that has a binding ability almost identical to welchol.

    Modified Citrus Pectin: A fiber made from the peel of citrus fruits that has a high affinity for lead, but also other heavy metals. It also has some immune-modulating properties.

    Fiber: Plant fibers have a weak affinity for many different toxins. Fiber can easily be obtained through the diet or supplemented.

    Humic and Fulvic Acids: These are made of decomposed plant matter, essentially dirt. They have been shown to detox glyphosate.

    Intestinal Metal Detox: A specially designed silica molecule that has a very high affinity for heavy metals.

    When choosing binders, sourcing is extremely important. Algaes, clays, and charcoal are notorious for being contaminated with toxins themselves, so cheapening out can actually make you worse. For this reason, it is important to make sure you are buying high-quality binders.

    The binder that works best for someone can also differ greatly based on the specific toxin load. What works well for someone can also change during different phases of treatment. Because binders can bind to nutrients, they should also be taken away from food. It is generally recommended to take them at least 30 minutes before, or 1 hour after eating or taking any supplements or medications. Binders can also cause constipation, so make sure to take them with plenty of water. Chasing them with magnesium citrate can also help reduce constipation. If it persists, a different binder may be needed.
    Quote A safe and effective way to detox aluminum, scientist reports
    by: Lori Alton, staff writer | March 18, 2019


    (NaturalHealth365) Truth be told, the presence of aluminum in the environment is nothing new. This naturally-occurring metal is the third most prevalent element on the planet. But, to be clear: aluminum has no biological value inside the human body – which makes the demand for an effective way to detox more important than most people can imagine.

    No doubt, the modern ‘abundance’ of aluminum in processed foods, cookware, food storage wraps and medications has raised concerns among many integrative healthcare providers – who view the accumulated toxicity of aluminum to be a contributing factor to the rising rates of autism and Alzheimer’s disease.

    Now, a study highlights the ability of silicon-rich mineral water to safely decrease levels of aluminum in the body. Even more encouragingly, consumption of this kind of water was associated with improvements in cognition among individuals with Alzheimer’s disease.

    Why an effective way to detox aluminum is so important
    To repeat the undeniable truth: aluminum – which has no nutritional value and serves no purpose in the human body – can enter the system through ingestion, inhalation or absorption. This unwanted metal then accumulates in the lungs, liver, thyroid, bone and brain – where it can cause harmful oxidative stress in tissues and cells.

    One of the primary reasons for the alarm over aluminum is that autopsies of patients with Alzheimer’s disease have shown elevated levels of inflammation-causing aluminum in the brain.

    And, animal studies have shown that increased aluminum accumulation is associated with the formation of neurofibrillary tangles associated with Alzheimer’s disease.

    Did you know? The liver is the most important detoxifying organ in the body. When the liver can’t effectively neutralize and dispose of toxins, they accumulate in the body. Two essential nutrients for healthy liver function are milk thistle and glutathione. These two ingredients - plus much more – are now available in an advanced liver support formula. Click here to learn more.

    Note: animal studies have shown that aluminum is associated with problems with learning, cognition, memory and coordination in non-aged animals as well.

    In addition, some research suggests that aluminum inhibits the uptake of important neurotransmitters – such as dopamine, norepinephrine and 5-hydroxytryptamine – needed for restful sleep, stable mood, cognition and alertness.

    Aluminum associated with many other health problems – including NAFLD
    Aluminum toxicity can play havoc with a wide variety of body systems – and lead to many chronic disease conditions.

    Because aluminum interferes with the metabolism of iron, chronic exposure can cause anemia.

    Aluminum toxicity can also cause or worsen nonalcoholic fatty liver disease – which is currently approaching epidemic proportions in the industrialized world. And, aluminum toxicity has been associated with kidney damage – as well as with increased risk of multiple sclerosis, Parkinson’s disease and amyotrophic lateral sclerosis, or ALS.

    According to Analytical Research Labs, Inc., the prevalence of aluminum toxicity has soared recently, with 80 percent of individuals tested for metal toxicity displaying excessively high levels of aluminum in hair samples.

    Note: hair samples are generally considered as among the most reliable ways of evaluating metal toxicity – as long as hair has not been washed at the laboratory prior to testing.

    Early symptoms of aluminum toxicity include headaches, colic, dry skin, heartburn, flatulence and increased susceptibility to respiratory infections.

    According to ARL, more advanced symptoms of aluminum toxicity can involve memory loss, confusion and paralytic muscular conditions.

    Study reveals: Just three months of drinking a ‘special kind’ of water yields encouraging results
    In a study conducted by Professor Christopher Exley, PhD and published in Journal of Alzheimer’s Disease, volunteers with Alzheimer’s disease drank a liter of silicon-rich mineral water a day for twelve weeks. (Silicon is a naturally-occurring metalloid element that appears in foods such as Bell peppers, soybeans and asparagus. It is also present in mineral water).

    And the results were impressive.

    Dr. Exley – a professor of Bioinorganic Chemistry at Keele University – reported that the consumption of the mineral water led to decreases of up to 70 percent in the volunteers’ body burden of aluminum.

    And, drinking the silicon-rich water for 12 weeks produced significant, clinically relevant improvements in cognitive functioning among some of the participants – with no reported side effects.

    Dr. Exley explained that the soluble silicon found in mineral water follows water molecules through the intestinal walls and into the bloodstream, where it then combines with aluminum to form a compound called hydroxyaluminosilicate.

    This substance is more easily filtered from the blood than aluminum is, causing more efficient excretion via the kidneys and urine.

    This exciting research suggests that drinking a liter a day of silicon-rich mineral water is a safe, inexpensive and effective natural method of accelerating the removal of aluminum from the body.

    Dr. Exley advises both the Fiji and Volvic brands as containing optimal amounts of silicon. (Check the label to make sure the brand contains a minimum concentration of 30 mg/L, or 30 ppm, of silica.)

    Health tip: For maximum benefit, opt for unsweetened, unflavored varieties of mineral water.

    Incidentally, Dr. Exley is not the only health expert to advise using silicon or silica formulations to detoxify aluminum.

    Christine Schaffner, ND, a board-certified naturopathic physician and noted aluminum toxicity expert, also recommends Enterosgel, a silica-based binder, to reduce the body burden of aluminum.

    Reduce aluminum exposure with common-sense choices
    While it is impossible to avoid all aluminum, you can reduce your exposure significantly.

    Simple steps include bypassing the use of aluminum cookware, aluminum foil wrapping and aluminum cans – especially when it comes to acidic foods and beverages. Experts warn that cooking tomatoes in an aluminum pan, or sipping juice from a can, could lead, over time, to aluminum toxicity in susceptible individuals.

    Carefully checking labels of health and beauty products can help you detect aluminum in unexpected places.

    For instance, aluminum is found in antiperspirants, in the form of aluminum chlorhydrate.

    Aluminum is also in commercial antacids such as Rolaids, Maalox and Mylanta. (Note: the Tums brand, however, is free of aluminum).

    Even if you’re ‘symptom-free,’ don’t ignore these warnings
    As you can imagine – by now, the importance of a high-quality personal water filtration system can’t be overstated. Just make sure your system for water purification removed aluminum – before you buy.

    Of course, no discussion about aluminum would be complete without warning you about the the current vaccine schedule and geoengineering programs designed to ‘control’ the weather. These are two of the biggest ways that people are getting exposed to aluminum.

    Plus, as if the above mentioned sources weren’t enough, aluminum can appear in foodstuffs such as cocoa, baking powder and even salt. But, you can still benefit from small – yet significant – changes. For example, just opt for sea salt over (heavily processed) commercial salt.

    In addition to drinking mineral water, you can detoxify your body with proper nutrition, along with appropriate dosages of vitamin C and E.

    Other natural neutralizers include chlorella, cilantro, the mineral selenium, the herb horsetail (naturally rich in silica) and the amino acid N-acetyl-cysteine.

    Of course, always consult with an experienced integrative physician before supplementing – or before undergoing any sort of detoxification program.

    Finally, don’t forget the garlic, onions, and cruciferous vegetables (such as broccoli, Brussels sprouts, arugula and kale). These beneficial foods can help promote the production of glutathione – the body’s ‘master antioxidant.’

    Our current era has been dubbed “The Age of Aluminum” – for good reason. But mineral water – safe, non-invasive and cost-effective – just might be your most important ally for surviving it.

    So, raise a glass (of mineral water) to your health!

    Sources for this article include:

    HippocraticPost.com
    ARLTMA.com
    NaturalHealth365

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    Default Re: Glyphosate remediation

    The best thing we can do is grow our own organic food and protect the right to have a garden. Good news here.

    Quote Florida Residents Defeat Front-Yard Garden Ban
    Jim Satney May 22, 2019


    Floridians claimed victory last month when the state’s legislature passed a bill that allows residents to grow gardens in their front yards. Sadly, the state has a history of harassing residents who choose to grow gardens on their properties.

    The state’s new law now forces all cities to respect people’s property rights, which includes the basic and survival concept of growing food. The new bill prohibits “local governments from regulating vegetable gardens on residential properties.”

    The Florida Senates’ decision to allow residents to grow gardens in their front yards was sparked by a couple’s lawsuit against the city of Miami Shores. Hermine Ricketts and Tom Carroll used their Miami Shores property to provide food for 17 years. However, the city decided to harass the couple, thrusting the couple and city into a national legal debate. In November of 2017, a state appeals court ruled against the couple. The couple also faced a series of fines back in 2013 after the city passed an ordinance banning front yard gardens. The couple is unable to use their backyard due to lack of sunlight.

    “What we’ve seen over the last several years is a movement to locally source food to have food be more organic and be more natural and not have to be subject to so many preserves and chemicals so that it travels across the country,” Bradley said. “Instead, it can be in your backyard to be eaten.”

    SB 82 prohibits municipalities from banning vegetable gardens on any part of a Florida residents property. It should be noted that the verbiage of SB 82 leaves out water regulation, something the state or city could regulate during drought conditions. Sen. Rob Bradley’s bill does not intervene in homeowners association rules.

    Learning how to build a survival garden is a basic prepper need. No state should be given such sweeping power that allows for telling people they can’t grow tomatoes on their property. The fact is, there are plenty of neighborhoods that are governed by homeowners associations. If you fear a neighbor growing cucumbers and ghost peppers in their front yard, purchase a home in a regulated neighborhood.


    Author: Jim Satney

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    Default Re: Glyphosate remediation

    "It deserves immediate attention with significant resources to avoid
    a general collapse of our critical agricultural infrastructure."
    Don Huber
    Leaked letter in 2011 that went viral but never resulted in any action.

    Quote Letter Sent to Secretary Vilsack
    by Dr. Huber That Was Leaked
    January 16, 2011
    Dear Secretary Vilsack:
    A team of senior plant and animal scientists have recently brought to my
    attention the discovery of an electron microscopic pathogen that appears
    to significantly impact the health of plants, animals, and probably human
    beings. Based on a review of the data, it is widespread, very serious, and
    is in much higher concentrations in Roundup Ready (RR) soybeans and
    corn — suggesting a link with the RR gene or more likely the presence of
    Roundup. This organism appears NEW to science.
    This is highly sensitive information that could result in a collapse of US
    soy and corn export markets and significant disruption of domestic food and
    feed supplies. On the other hand, this new organism may already be responsible for significant harm (see below). My colleagues and I are therefore moving our investigation forward with speed and discretion, and seek assistance
    from the USDA and other entities to identify the pathogen’s source, prevalence, implications, and remedies.
    We are informing the USDA of our findings at this early stage, specifically
    due to your pending decision regarding approval of RR alfalfa. Naturally, if
    either the RR gene or Roundup itself is a promoter or co-factor of this pathogen, then such approval could be a calamity. Based on the current evidence,
    the only reasonable action at this time would be to delay deregulation at least
    until sufficient data has exonerated the RR system, if it does.
    For the past 40 years, I have been a scientist in the professional and
    military agencies that evaluate and prepare for natural and manmade
    biological threats, including germ warfare and disease outbreaks. Based
    on this experience, I believe the threat we are facing from this pathogen is
    unique and of a high risk status. In layman’s terms, it should be treated as
    an emergency.
    A diverse set of researchers working on this problem have contributed
    various pieces of the puzzle, which together presents the following disturbing scenario:
    Unique Physical Properties
    This previously unknown organism is only visible under an electron
    microscope (36,000X), with an approximate size range equal to a medium
    size virus. It is able to reproduce and appears to be a micro-fungal-like organism. If so, it would be the first such micro-fungus ever identified. There is
    strong evidence that this infectious agent promotes diseases of both plants
    and mammals, which is very rare.
    Pathogen Location & Concentration
    It is found in high concentrations in Roundup Ready soybean meal and
    corn, distillers meal, fermentation feed products, pig stomach contents, and
    pig and cattle placentas.
    Linked with Outbreaks of Plant Disease
    The organism is prolific in plants infected with two pervasive diseases
    that are driving down yields and farmer income — sudden death syndrome
    (SDS) in soy, and Goss’ wilt in corn. The pathogen is also found in the fungal
    causative agent of SDS (Fusarium solani fsp glycines).
    Implicated in Animal Reproductive Failure
    Laboratory tests have confirmed the presence of this organism in a wide
    variety of livestock that have experienced spontaneous abortions and infertility. Preliminary results from ongoing research have also been able to reproduce abortions in a clinical setting.
    The pathogen may explain the escalating frequency of infertility and
    spontaneous abortions over the past few years in US cattle, dairy, swine, and
    horse operations. These include recent reports of infertility rates in dairy
    heifers of over 20%, and spontaneous abortions in cattle as high as 45%.
    For example, 450 of 1,000 pregnant heifers fed wheatlage experienced
    spontaneous abortions. Over the same period, another 1,000 heifers from the
    same herd that were raised on hay had no abortions. High concentrations of
    the pathogen were confirmed on the wheatlage, which likely had been under
    weed management using glyphosate.
    Recommendations
    In summary, because of the high titer of this new animal pathogen in
    Roundup Ready crops, and its association with plant and animal diseases
    that are reaching epidemic proportions, we request USDA’s participation in a
    multi-agency investigation, and an immediate moratorium on the deregulation of RR crops until the causal/predisposing relationship with glyphosate
    and/or RR plants can be ruled out as a threat to crop and animal production
    and human health.
    It is urgent to examine whether the side-effects of glyphosate use may have
    facilitated the growth of this pathogen, or allowed it to cause greater harm
    to weakened plant and animal hosts. It is well-documented that glyphosate
    promotes soil pathogens and is already implicated with the increase of more
    than 40 plant diseases; it dismantles plant defenses by chelating vital nutrients; and it reduces the bioavailability of nutrients in feed, which in turn can
    cause animal disorders. To properly evaluate these factors, we request access
    to the relevant USDA data.
    I have studied plant pathogens for more than 50 years. We are now seeing
    an unprecedented trend of increasing plant and animal diseases and disorders. This pathogen may be instrumental to understanding and solving this
    problem. It deserves immediate attention with significant resources to avoid
    a general collapse of our critical agricultural infrastructure.
    Sincerely,
    COL (Ret.) Don M. Huber
    Emeritus Professor, Purdue University
    APS Coordinator, USDA National Plant Disease Recovery System
    (NPDRS)https://www.organicconsumers.org/sit...2011_Huber.pdf
    Quote USDA Scientist Reveals All
    Glyphosate Hazards to Crops, Soils, Animals, and Consumers
    Don Huber painted a devastating picture of glyphosate and GM crops at UK Parliament Dr Eva Sirinathsinghji

    In less than an hour, Don Huber, professor emeritus at Purdue University and USDA senior scientist (see Box) delivered to the UK Houses of Parliament a damning indictment of glyphosate agriculture as a most serious threat to the environment, livestock, and human health [1].

    Don Huber
    Don Huber, Emeritus Professor at Purdue University and senior scientist on USDA’s National Plant Disease Recovery System, has been a plant physiologist and pathologist for over 40 years. His academic career began with 8 years as a cereal pathologist at the University of Idaho, and the next 35 years at Purdue University where he specialised in soil-borne disease control, physiology of disease, and microbial ecology. For the past 20 years, he has conducted extensive research into the effects of glyphosate on crops, in response to the increase in crop diseases on glyphosate-applied fields.

    Since his letter to the US Secretary of State Tom Vilsak was leaked in February 2011, there has been a great deal of controversy over what Huber described as a pathogen “new to science” and abundant in glyphosate-tolerant GM crops (see [2] Emergency! Pathogen New to Science Found in Roundup Ready GM Crops?, SiS 50). As he concluded in the letter: “We are now seeing an unprecedented trend of increasing plant and animal diseases and disorders. This pathogen may be instrumental to understanding and solving this problem”.

    His talk linked glyphosate to reduced nutrient availability in plants, increasing plant diseases, the emergence of a new pathogen, animal illness and possible effects on human health (see [3, 4] Glyphosate Tolerant Crops Bring Death and Disease, Scientists Reveal Glyphosate Poisons Crops and Soil, SiS 47).

    Pathogen new to science
    The conversion of US agriculture to monochemical herbicide practice has resulted in the extensive use of glyphosate herbicides. Coincidentally, farmers have been witnessing deterioration in the health of corn, soybean, wheat and other crops, and epidemics of diseases in small grain crops. All are associated with the extensive use of glyphosate, which has increased further since the introduction of glyphosate-tolerant, Roundup Ready (RR) crops.

    Glyphosate immobilises nutrients required to maintain plant health and resistance to disease. This weakening of the plants defence could explain the infestation of GM crops with the new pathogen, which has now been observed in horse, sheep, pigs, cows, chicken, multiple animal tissues including reproductive parts (semen, amniotic fluid), manure, soil, eggs, milk, as well as the common fungal pathogen that is currently infesting RR crops, Fusarium solani fsp glycines mycelium. All are coming into contact with glyphosate either through direct exposure or consumption through animal feed. It is also highly abundant in crops suffering from plant Goss’ wilt and sudden death syndrome.

    The pathogen can be cultured in the lab, and has been isolated from livestock foetal tissue, replicated in the lab and re-introduced back into the animals. It appears to be very common and may well be interacting with the effects of glyphosate on both plants and animals, exacerbating disease and causing reproductive failure in livestock (see below). Although great expectations have been placed on Huber to publish his findings, he insists that before this can be done, further resources are necessary to be able to characterise the ‘entity’ and identify what type of species it is, including sequencing of its genome. This is a slow process and once complete, it is his intention to publish the work in a peer-reviewed journal.

    Understanding glyphosate’s mode of action
    Recognising glyphosate’s mechanism of action is the key to understanding how it may exert detrimental effects on the health of crops, animals, and the environment alike. Glyphosate is a broad-spectrum herbicide that interacts with a range of physiological processes in the plant and its environment. Although it is most commonly recognised to work through inhibition of the plant enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) involved in the production of aromatic amino acids in the shikimate pathway, it was actually first patented as a strong metal-chelator that binds to metals including manganese, magnesium, iron, nickel, zinc and calcium, many of which are important micronutrients acting as co-factors for plant enzymes in different physiological processes including the plants’ defence system. Indeed, it is actually through chelation of manganese that the EPSPS enzyme is inhibited.

    Rendering plants more susceptible to disease through glyphosate’s pathogenic activity is actually the way it exerts its herbicidal activity. This is done not just through immobilising nutrients in the plant but also impacting the agricultural system as a whole. Consistently, if glyphosate does not reach the root of a plant or the plant is grown in a sterile soil, the plant is not killed.

    Once in the soil, glyphosate is later immobilised through the chelation of cations, and is therefore very stable and not easily degraded. However, phosphorus (including phosphorus fertilisers) can desorb the herbicide, making it active once again in the soil.

    Glyphosate interferes negatively with many components of agriculture
    Huber stressed that agriculture is an integrated system of many interacting components, which together determine crop health and therefore yield. This concept is undervalued, and the sooner this is recognised, the sooner we will be able to reap the full genetic potential of our crops.

    The three main components of an agricultural system are 1) the biotic environment including beneficial organisms for example, nitrogen-fixing microbes and mineralizers; 2) the abiotic environment including nutrients, moisture, pH; and 3), defence against pathogens that damage crops. The genetic potential of a plant can be achieved by minimising the stress placed on these components through improving plant nutrition and physiology and prevention of diseases and pests.

    We have been repeatedly told that to meet the world’s needs for food production we must resort to GM crops and chemical agriculture. However, glyphosate detrimentally interacts with all the agricultural components, so much so that an estimated 50 percent of the potential crop yields are currently being lost (see Figure 1).



    Figure 1 Interactions of glyphosate with plant and soil biology; adapted from Huber’s presentation

    As shown in figure 1, glyphosate interacts with a wide range of health determinants, which intensifies stress and reduces crop yields. Not only does it accumulate in the plant tissues (shoot and root tips, reproductive structures and legume nodules), it accumulates in the roots where it then leaks into the soil and harms beneficial microorganisms in the soil including those that act as biological controls of pathogens. The obvious consequence is the increased virulence of soil-borne pathogens that lead to disease.

    Glyphosate immobilises nutrients critical for plant defence system and other functions
    One of Huber’s important discoveries was the close correlation of all the known conditions affecting the disease ‘take-all’ with the availability of manganese to the plant and its physiological effect on resistance to this pathogen.

    Micronutrients are the activators or inhibitors of many critical physiological functions. Thus, a deficiency or change in availability of these regulatory elements can greatly affect plant growth and resistance to diseases and pests. Those metabolic pathways producing secondary anti-microbial compounds, pathogen-inhibiting amino acids and peptides, hormones involved in cicatrisation (walling off pathogens), callusing, and disease escape mechanisms can all be compromised by glyphosate.

    Micronutrients are also necessary for other processes in a plant. Manganese for example is not only involved in co-activating the EPSPS enzyme, with up to 25 other enzymes known to be affected by manganese chelation. Such enzymes are necessary for photosynthesis, in assimilating carbon dioxide in the electron transport chain, along with zinc. It also helps in the synthesis of chlorophyll and in nitrate assimilation. Numerous enzymes requiring other mineral co-factors are also affected, among them enzymes of the shikimate pathway, to which EPSPS belongs, are responsible for plant responses to stress and the synthesis of defence molecules against pathogens, such as amino acids, lignins, hormones, phytoalexins, flavenoids and phenols.

    Consistent with what is known about the role of micronutrients and glyphosate, the levels of key minerals have been measured in transgenic RR soybeans and found to be lower than those in isogenic non-transgenic varieties. Manganese was reduced by as much as 45 %, while iron was reduced by 49 % [5]. Similar deficiencies in mineral content have been found in non-GM varieties, suggesting that the glyphosate, and not the RR transgene, is responsible for reducing mineral availability [6]. Glyphosate reduces photosynthesis, water uptake, amino acid production as well as lignin, a molecule conferring mechanical strength of the plant and crucial for conducting water through plant stems [7, 8].

    As Huber stated, the consequences of these nutrient deficiencies is that “crops don‘t look as good, are not as productive or rigorous, and are slower growing“ (see Figure 2). He noted yield drags of 26 % for RR soybeans. Furthermore, with current concerns for global warming, plants that are up to 50 % less water-efficient, such as RR crops, are counter-productive and can only exacerbate problems.

    Huber stressed that there is nothing in the glyphosate tolerant crops that operates on the glyphosate applied to them. Consequently, although they have enough resistance to prevent them from dying (conferred by the EPSPS transgene), their overall physiological function is compromised by glyphosate. It therefore affects GM as well as non-GM crops through residual levels of glyphosate in the ground.

    In addition to chelating nutrients in the plants, glyphosate can lower mineral content through damaging beneficial soil organisms, including microbes producing indole-acetic acid (a growth-promoting auxin), earthworms, mycorrhizae associations, phosphorus & zinc uptake, microbes such as Pseudomonads, Bacillus that convert insoluble soil oxides to plant-available forms of manganese and iron, nitrogen-fixing bacteria Bradyrhizobium, Rhizobium, and organisms involved in the biological control of soil-borne diseases that reduce root uptake of nutrients.



    Figure 2 Effects of long-term glyphosate on crop health; adapted from Huber’s presentation

    Glyphosate increases incidence and virulence of soil-borne pathogens
    Thirty-four diseases have been reported in the scientific literature to increase in incidence as a result of glyphosate weed-eradication programmes. They affect a wide variety of crops from cereals to bananas, tomatoes, soybean, cotton, canola, melon and grapes [9]. Some of these diseases are considered ‘emerging’ or ‘re-emerging’ as they had not caused serious economic losses in the past. This has worrying implications for the agricultural sector with the US now in its fourth year of epidemics of Goss’ wilt and sudden death syndrome and eighteenth year of epidemic of Fusarium fungal colonisation resulting in root rot and Fusarium wilt. Not only does glyphosate affect disease susceptibility, there is also evidence of increased disease severity. Examples include ‘take-all’; Corynespora root rot in soybean; Fusarium spp diseases, including those caused by Fusarium species that are ordinarily non-pathogenic. Head-scab caused by Fusarium spp of cereals increases following glyphosate application, which is also now prevalent in cooler climates when previously it was limited to warmer climates.

    Food and Feed Safety Concerns
    Nutrient-deficient, transgenic plants suffering from disease that also harbour herbicide residues, presents an array of possible safety hazards to animals and humans. According to Huber, possible harm include direct toxicity of glyphosate itself, which has been shown to cause endocrine disruption, DNA damage, reproductive and developmental toxicities, neurotoxicity, cancer, and birth defects (see [10]Glyphosate Toxic and Roundup Worse,SiS26; [11]Death by Multiple Poisoning, Glyphosate and Roundup,SiS42; [12]Ban Glyphosate HerbicideNow.SiS43; [13]Lab Study Establishes Glyphosate Link to Birth Defects,SiS48). Furthermore, allergies are on the rise, and animals are showing allergy responses, including inflamed irritated stomachs (Figure 3), discoloration of stomach lining, leakage of intestines as well as behavioural symptoms of irritability and anti-social behaviour in cows (abnormal for herd animals). Inflammatory bowel disease in humans has risen 40 percent since 1992, which may be related to consumption of GM foods, although this has not yet been proven.



    Figure 3 Stomach shows allergic response of discolouration and inflammation in GMO fed pig (right) compared with control (left)

    The increase in infestation of crops with fungal pathogens that produce toxins is an added concern. Mycotoxins, including fusarium toxins as well as aflatoxins released by Aspergillus fungi are carcinogenic and have forced imports of wheat into the US due to unsafe levels found in domestic harvests.

    Triple whammy of reproductive toxicity caused by glyphosate
    In 2002, the Cattlemen’s Association gave a statement to US Congress on the serious and puzzling rises in reproductive problems. It said: “high numbers of foetuses are aborting for no apparent reason. Other farmers successfully raise what look to be normal young cattle, only to learn when the animals are butchered that their carcasses appear old and, therefore, less valuable...The sporadic problem is so bad both in the United States and abroad that in some herds around 40-50 percent of pregnancies are being lost.. [and] the viability of this important industry is threatened.”

    Glyphosate appears to be able to induce reproductive failures through three separate mechanisms. The first, mentioned above is the endocrine dysfunction caused by direct toxicity of glyphosate.

    The second is the reduced nutrient content having consequential effects on the nutritional status of animals. Manganese in animals, as in plants, is an essential nutrient, and deficiencies have been associated with a variety of diseases as well as reproductive failures, which are becoming increasingly common in livestock. One study performed in Australia following two seasons of high levels of stillbirths in cattle found that all dead calves were manganese deficient [14]. Furthermore, 63 percent of babies with birth defects were also deficient. Manganese is known to be important for mobilising calcium into bones, correlating with abnormal bone formation in these calves.

    Third, the unknown pathogenic ‘entity’ may be associated with inducing pseudo-pregnancies. As far back as 1998, a suspect agent was found in reproductive tissue of livestock. It has now been isolated in high concentrations from semen, amniotic fluid as well as placental tissue. It has also been found in aborted foetal tissue. Some farms are reporting up to 50 percent fewer conceptions in animals due to increased miscarriages and pseudo-pregnancies. Although evidence of the widespread presence of this new pathogen is clear, Don Huber suggested the need for further research to understand not only what kind of pathogen it is, but importantly, the effects it is having on the health of plants as well as animals.

    To conclude
    Over 100 peer reviewed papers have been published by Huber and other scientists on the detrimental effects of glyphosate. Glyphosate increases disease in plants (as well as animals), prompting Huber to write to the Secretary of Agriculture. It may be linked to many health problems in animals and humans, which are an added cost to all the failed promises of a new agricultural technology that would feed the world. As Huber concluded, the “public trust has been betrayed.”

    Article first published 09/01/12

    References
    All-Party Parliamentary Group on Agroecology Meeting, Huber DM “The effects of glyphosate (Roundup®) on soils, crops and consumers: new diseases in GM corn and soy and animals fed with it”, 20 November 2011, Houses of Parliament, UK. http://agroecologygroup.org.uk/index...gs/2011-11-01/
    Ho MW. Emergency! Pathogen new to science found in Roundup Ready GM crops? Science and Society 50, 10-11, 2011.
    Ho MW. Glyphosate Tolerant Crops Bring Death and Disease. Science in Society 47, 2010, 12-15
    Ho MW. Scientists Reveal Glyphosate Poisons Crops and Soil. Science in Society 47, 2010, 12-15
    Zobiole LHS, Oliveira RS Jr, Huber DM, Constantina J, Castro C, Oliveira FA, Oliveira A. Jr. Glyphosate reduces shoot concentrations of mineral nutrients in glyphosate-resistant soybeans. Plant Soil 2010, 328:57-69
    Cakmak, I, Yazici, A, Tutus, Y, and Ozturk L. Glyphosate reduced seed and leaf concentrations of calcium, magnesium, manganese, and iron in non-glyphosate resistant soybean. European Journal of Agronomy 2009, 31, 114-119.
    Zobiole LHS, Silvério de Oliveira RS Jr, Kremerb RB, Constantina J, Bonatoc CM, Muniz AS. Water use efficiency and photosynthesis of glyphosate-resistant soybean as affected by glyphosate. Pesticide Biochemistry and Physiology 2010, 97, 182-193
    Zobiole LHS, Bonini EA, Oliveira RS Jr, Kremer RJ, and Ferrarese-Filho O. Glyphosate affects lignin content and amino acid production in glyphosate-resistant soybean. Acta Physiologiae Plantarium 2010, 32, 831-837
    Johal GS & Huber DM. Glyphosate Effects on Disease and Plants. European Journal of Agronomy 2009, 31, 144-152
    Ho MW and Cummins J. Glyphosate toxic and Roundup worseScience in Society 26 2005, 12.
    Ho MW and Cherry B. Death by multiple poisoning, glyphosate and Roundup.Science in Society 422009, 14
    Ho MW. Ban glyphosate herbicides now.Science in Society 43 2009, 34-35
    Ho MW. Lab study establishes glyphosate link to birth defects.Science in Society 48 2010, 32-33
    McLaren PJ, Cave JG, Parker EM, Slocombe RF. Chondrodysplastic calves in Northeast Victoria. Veterinary Pathology 2007, 44, 342-54
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    Quote Published on Jun 14, 2016
    Dr. Don Huber, Professor Emeritus of Plant Pathology at Purdue University, holds B.S. and M.S. degrees from the University of Idaho, a Ph-D from Michigan State University, and is a graduate of the US Army Command & General Staff College and Industrial College of the Armed Forces. He was Cereal Pathologist at the University of Idaho for 8 years before joining the Department of Botany & Plant Pathology at Purdue University in 1971. His agricultural research the past 55 years has focused on the epidemiology and control of soilborne plant pathogens with emphasis on microbial ecology, cultural and biological controls, nutrient-disease interactions, pesticide-disease interactions and techniques for rapid microbial identification. On today’s episode of Bulletproof Radio, Dave and Dr. Huber talk about glyphosates, GMOs, natural mycotoxins, fertility, concerns for the global population, biological system and more. Enjoy the show!
    Last edited by Delight; 24th May 2019 at 05:43.

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    Default Re: Glyphosate remediation

    Quote How do we Heal from GMOS and Roundup? by Jeffrey M. Smith
    Published on Jun 5, 2019
    Studies show how a NON-GMO Organic Diet helped 3250 people recover from 28 disorders.

    The biotech industry's claim that genetically modified (GM) foods are safe is shattered in this groundbreaking lecture. Safety assessments on GM crops are not competent to identify the health problems, and industry research is rigged to avoid finding problems.

    This lecture is for anyone wanting to understand GM technology, to learn how to protect themselves, or to share their concerns with others. It is presented in the clear, accessible style that made Jeffrey Smith's Seeds of Deception the world's best-selling book on genetically engineered foods.

    The leading consumer advocate promoting healthier non-GMO choices, Jeffrey Smith’s meticulous research documents how biotech companies continue to mislead legislators and safety officials to put the health of society at risk and the environment in peril. His work expertly summarizes why the safety assessments conducted by the FDA and regulators worldwide teeter on a foundation of outdated science and false assumptions, and why genetically engineered foods must urgently become our nation’s top food safety priority.

    Mr. Smith’s feature-length documentary Genetic Roulette-The Gamble of Our Lives was awarded the 2012 Movie of the Year (Solari Report) and the Transformational Film of the Year (AwareGuide). Described as a “life-changer” and seen by millions worldwide, the film links genetically engineered food to toxic and allergic reactions, infertility, digestive disorders, and numerous problems that have been on the rise in the US population since genetically modified organisms (GMOs) were introduced
    .


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    Default Re: Glyphosate remediation

    If you see this Onawah, I will miss your presence in this information sharing. May we all be healed. The chemical industry was directly connected with war and genocide from its inception.

    Quote The Real Truth About Health
    Published on Jun 7, 2019
    What the Science Says About GMO'S, Seeds, Soil, Pesticides and the Best Way to Grow Healthy Food with Vandana Shiva, Ph.D., Caitlin Shetterly, Jeffrey Smith, Carey Gillam

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    Default Re: Glyphosate remediation

    I will miss you also Onawah..and thank you Delight for this very important thread and info it contains.

    William.
    TRUTH and BALANCE

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    "Dr. Jill uses functional medicine to help you find answers to the cause of your illness and addresses the biochemical imbalances that may be making you feel ill. She'll help you search for underlying triggers contributing to your illness through cutting edge lab testing and tailor the intervention to your specific needs as an individual. She may use diet, supplements, lifestyle changes or medication to treat your illness but will seek the most gentle way to help your body restore balance along with the least invasive treatment possible."

    Quote Glyphosate is Being Inserted Into Your Proteins — By Mistake

    By Jill Carnahan, MD
    July 22, 2019

    Author: Jill Carnahan, MD
    http://www.jillcarnahan.com

    Nothing incites anger and fear in us quite like the thought that we are being slowly poisoned by toxins in our food and water. From endocrine disrupting chemicals in everyday household products to lead in drinking water, it seems that we are increasingly at risk of developing diseases by things that we often have no control over.

    And glyphosate is no exception.

    The reports of harmful effects of glyphosate are exploding — within the medical and scientific community as well as the general public. At a time when bee populations are already declining, a recent study reported that glyphosate perturbs gut bacteria of bees, making them susceptible to infection.1

    But how exactly does this highly controversial chemical affect humans? Glyphosate toxicity is a topic I’ve written about numerous times. This time we’ll talk specifically about the various ways glyphosate exposure could lead to devastating health consequences, one of which includes pretending to be glycine, an amino acid that is crucial for protein synthesis.



    Glyphosate’s Pathways to Pathology
    Glyphosate acts by disrupting the shikimate pathway (also known as the shikimic acid pathway), a seven-step metabolic pathway used by plants to synthesize the aromatic amino acids tryptophan, phenylalanine, and tyrosine.2

    In plants, these amino acids are used as precursors for numerous natural products, such as pigments, alkaloids, hormones, and parts of the cell wall. Glyphosate inhibits the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), a key component of the shikimate pathway, causing plants to die.

    The shikimate pathway is absent in animals, including humans. In fact, humans don’t make tryptophan, phenylalanine, or tyrosine at all, which means we need to get them from our food. This led to the acceptance of a dogma that glyphosate cannot harm humans.

    But the shikimate pathway is present in microorganisms, including your gut microbiota.

    For this reason, scientists Anthony Samsel and Stephanie Seneff believe that glyphosate can disturb the gut microbiome, preventing them from being able to produce essential nutrients for our bodies. Glyphosate also accumulates in your tissues over time, contributing to the development of diseases and disorders.

    Samsel and Seneff published five commentaries on the potential pathways by which glyphosate could lead to pathology. In their research, Samsel and Seneff report that the main toxic effects of glyphosate are as follows:

    Interference with function of cytochrome (CYP) P450 family of enzymes
    Chelation of important minerals (iron, cobalt, manganese, etc.)
    Interference with synthesis of methionine (which supplies sulfur), leading to shortages of critical neurotransmitters and folate
    Disruption of sulfate synthesis and sulfate transport
    Substitution of glycine for glyphosate during protein synthesis
    Let’s take a brief look at a few of these hypotheses.



    Inhibition of CYP450 Enzymes
    In their first commentary on the health impacts of glyphosate, Drs. Samsel and Seneff linked glyphosate ingestion to disruption of gut bacteria, impairment of sulfate transport, and suppression of the activity of cytochrome (CYP) P450 family of enzymes.3

    But why is CYP450 so important?

    The CYP450 family of enzymes is involved in the synthesis and metabolism of various molecules and chemicals, including those that are potentially toxic.4 Using evidence from multiple studies, Samsel and Seneff hypothesized that glyphosate could disrupt many of the CYP enzymes that are active in the liver, which could affect:

    Cholesterol synthesis and metabolism
    Vitamin D3 synthesis and metabolism
    Detoxification of xenobiotics
    Regulation of retinoic acid
    They also expected that glyphosate would travel throughout the bloodstream, disrupting any CYP enzymes it comes into contact with.



    Inhibition of Methionine Synthesis
    In addition to reduced levels of the aromatic amino acids tryptophan, phenylalanine, and tyrosine, glyphosate can also lower levels of serine, glycine, and methionine in glyphosate-sensitive cells. The reduction of methionine, in particular, can have serious consequences. Methionine is one of four common sulfur-containing amino acids and is the initiating amino acid in virtually all eukaryotic protein synthesis.5

    When methionine synthesis is impaired, DNA methylation is also hindered. DNA methylation is the process by which a methyl (CH3) group is added to the DNA. It can alter the activity of the DNA, turning necessary biological switches on for optimal functioning. Optimal methylation can have a significant positive impact on:6

    DNA production
    Detoxification
    Eye health
    Liver health
    Cellular energy
    Fat metabolism
    Estrogen metabolism
    Because many neuronal diseases are associated with DNA methylation impairment, Samsel and Seneff believe that the reduction of methionine contribute to this defect.



    Metal Chelation
    In their third commentary, Samsel and Seneff introduce the link between glyphosate and manganese dysbiosis.7 Manganese is one of the 14 essential trace elements and place a role in various important processes, including:

    Antioxidant protection
    Glutamine synthesis
    Bone development
    Sperm motility
    Manganese is also a transition metal and an EPSPS catalyst, a substance that helps speed up chemical reactions. It is reasonable then, Seneff and Samsel argue, to expect that glyphosate, a metal chelator, could deplete the body of manganese. In fact, this is exactly how glyphosate kills plants.

    But what about in the human body? Samsel and Seneff propose that certain species of gut bacteria utilize manganese in various ways for protection from oxidative damage. The chelation of manganese by glyphosate would result in reduced numbers of essential gut bacteria.

    Samsel and Seneff also link chelation of manganese by glyphosate to the development of several neurological disorders and diseases. In particular, they point out that manganese chelation could cause the misfolding of prion proteins. Although the normal functions of prions are not fully understood, their misfolding has been shown to be involved in several prion diseases and other protein misfolding diseases, including:8

    Creutzfeldt-Jakob disease
    Gerstmann-Straussler-Scheinker syndrome
    Fatal familial insomnia
    Kuru
    Alzheimer’s disease
    Parkinson’s disease
    Huntington’s disease
    Type 2 diabetes
    Spinocerebellar ataxias
    Amyotrophic lateral sclerosis
    Prion proteins bind to the element copper in the body. However, Seneff and Samsel propose that they can also bind to manganese instead of copper, which causes the prion proteins to misfold.910 Manganese binding also prevents the degradation of proteins, a characteristic feature of prion diseases, and promotes prion protein aggregation.11



    Substitution of Glycine for Glyphosate During Protein Synthesis
    In their fifth commentary, Samsel and Seneff present a hypothesis linking glyphosate toxicity to mistakes made in protein synthesis.12 At the core of this proposal is the fact that glyphosate is very similar in structure to another amino acid that plays crucial roles in protein synthesis and human physiology, glycine.

    In fact, the chemical name of glyphosate is N-phosphomethyl-glycine, which indicates that it is a derivative of glycine.

    Still, how does glyphosate fool our cells’ proofreading mechanisms? Samsel and Seneff present a direct quote from another study to suggest that these mechanisms aren’t foolproof: “Certain structural analogues of the protein amino acids can escape detection by the cellular machinery for protein synthesis and become misincorporated into the growing polypeptide chain of proteins to generate non-native proteins.”13

    Samsel and Seneff cite another study to bolster their hypothesis that the substitution of glyphosate for glycine is possible. In a 2010 report, Godballe et al. used N-substituted glycines to construct mimics of antibacterial peptides called peptoids.14 The modification of the reactive side chain in glycine was moved to the backbone nitrogen, resulting in greater metabolic stability.

    The higher stability of peptoid chains can be beneficial in many ways because it allows antimicrobial agents to stay in the body for longer before being broken down. However, the resistance to proteolysis can have adverse effects when it comes to glyphosate, which can also be considered a peptoid unit. If glyphosate is mistaken for glycine and misincorporated into a peptide, Seneff and Samsel believe that it could interfere with the disassembly of the defective peptide. This could result in protein misfolding and the slow accumulation of undegraded and damaged peptide chains, possibly leading to disease.

    By this mechanism, Seneff and Samsel propose a link between glyphosate exposure and a large spectrum of diseases and disorders, some of which include:

    Diabetes
    Obesity
    Asthma
    Chronic obstructive pulmonary disease
    Pulmonary edema
    Adrenal insufficiency
    Hypothyroidism
    Alzheimer’s disease
    Amyotrophic lateral sclerosis
    Non-Hodgkin’s lymphoma
    Hypertension
    Glaucoma
    Infertility


    The Debate on Glyphosate Toxicity
    The commentaries by Samsel and Seneff aren’t without controversy. In a review titled “Facts and Fallacies in the Debate on Glyphosate Toxicity” published in 2017, Robin Mesnage and Michael N. Antoniou wrote that the commentaries are a “misrepresentation of glyphosate’s toxicity [that] misleads the public, the scientific community, and regulators. Although evidence exists that glyphosate-based herbicides are toxic below a regulatory set safety limits, the arguments of Samsel and Seneff largely serve to distract rather than to give a rational direction…”

    Regarding the first commentary, Mesnage and Antoniou argued that although CYP450 is inhibited by high levels (agricultural use concentrations) of glyphosate, typical environmental exposure levels do not show the same results.15 Additionally, they mention that Seneff and Samsel do not acknowledge animal studies in which environmentally-relevant levels of glyphosate show an increase in CYP450 activity, not suppression.16

    Furthermore, the reduction in CYP450 cannot be solely attributed to glyphosate toxicity. Samsel and Seneff point to a study in which rats exposed to Roundup at levels allowed for human consumption showed a reduction in CYP450 levels. However, glyphosate is not the only ingredient in Roundup. It also contains co-formulant adjuvants, which are highly toxic in their own right. Studies have established that co-formulants often make commercial pesticides more toxic than the active ingredient alone.1718 This means that the exact cause for CYP450 suppression is unclear.

    It’s also unclear whether glyphosate has any affect on the gut microbiome, especially at environmental exposure levels. While some studies demonstrate an adverse effect,19 others have reported no effects.20

    Mesnage and Antoniou also point out multiple logical fallacies in the commentaries. Samsel and Seneff propose that the chelation of manganese could cause it to out-compete copper in binding to prion protein. The misfolding that results is thought to contribute to prion diseases. However, the evidence of such effects is lacking.

    The authors also indicate that if glyphosate acts by sequestering manganese, that means it would make the micronutrient unavailable for participation in interactions with proteins. It would actually be unable to out-compete copper for binding to prion proteins. If this is true, then the chelation of manganese by glyphosate would have a protective effect against prion disease, not a causative one.

    The hypothesis regarding the substitution of glyphosate for glycine has also received criticism. Samsel and Seneff argue that glyphosate can replace glycine in peptoids, and therefore, it can also replace glycine in regular polypeptides. However, Mesnage and Antonious write, peptoids do not exist naturally in living organisms. Therefore, it is not valid to extrapolate the observations from the laboratory-manufactured peptoids to naturally-occurring polypeptides as they are structurally distinct.

    Perhaps the most striking argument against Samsel and Seneff’s fifth commentary is that direct experimentation has shown that glyphosate does not get incorporated into proteins.21 Studies involving E. coli cultured in the presence of high concentrations (1 g/L) of glyphosate showed that there were no shifts in molecular weight of proteins or incorporation of glyphosate in polypeptides. Had glyphosate been incorporated into the proteins of E. coli, protein molecular weight would have changed and glyphosate would have been detectable by the analytical methods used in the studies.



    7 Ways to Protect Yourself Against Glyphosate
    Despite the controversy, we know glyphosate use is widespread, and it’s getting more difficult to avoid. But there are ways to reduce your risk and possibly reverse some of its toxic effects. Here are a few ways you can safeguard yourself and your family against glyphosate.

    1) Extracts from Dandelions, Barberry, and Burdock
    Glyphosate is toxic to liver and embryonic cells at doses far below those used in agriculture. A few studies have suggested that a specific combination of plant medicinal herbs may have protective effects against glyphosate. In one study using rats, extracts from dandelion, barberry, and burdock reversed many of the adverse effects provoked by glyphosate when taken prior to and during the 8 days of exposure. Most of the biochemical disturbances caused by glyphosate were also reversed by the combination of plant extracts.22

    2) Charcoal and Humic Acids
    Animals like cows are frequently exposed to glyphosate through their feeds. A 2014 study reported that a treatment regimen with activated charcoal, sauerkraut juice, humic acids, and their combinations significantly reduced glyphosate in the cows’ urine. This enhanced the animals’ immune systems, which induced appropriate immune responses to Clostridium botulinum, the bacteria responsible for producing the neurotoxin botulinum.23

    Dr. Seneff believes that these treatments could also be effective in humans when trying to detox glyphosate.

    3) Important Nutrients
    Raising your sulfate levels isn’t easy because it can be hard to transport. Dr. Seneff recognizes several important nutrients that act as sulfur suppliers:

    Curcumin
    Garlic
    Vitamin C
    Probiotics
    Methyl tetrahydrofolate
    Cobalamin
    Glutathione
    Taurine
    Epsom salt baths
    4) Get Grounded
    Grounding is the direct physical contact between the body and the surface of the earth. Emerging research has shown that grounding (also called earthing) generates “a kind of electric nutrition.”24

    How does this occur?

    The hypothesis about grounding/earthing is based on the fact that the earth is satiated with free electrons. When two objects make contact, either directly or indirectly, there is an instantaneous migration of “mobile” electrons so that the electrical potentials of the two objects equalize. Some studies have suggested that these free electrons can have potent antioxidant and anti-inflammatory effects by neutralizing reactive oxygen species.25

    Simply put, the earth is a giant negatively-charged battery. By making direct contact with the ground, the electrons flow right into your body, helping you to regenerate the negative charge.

    5) Go Organic
    Although it may be difficult to completely avoid being exposed to glyphosate, eating an organic diet will reduce your exposure to the herbicide. Furthermore, it’ll increase the demand for foods that don’t use glyphosate. It’s also important to be careful with meat and dairy products, which can be sources of glyphosate exposure. Check with your local farms to find the healthiest meat and dairy products for you and your family.

    6) Eat Foods Containing Manganese
    Since glyphosate can chelate manganese, Dr. Seneff recommends eating foods high in manganese to replenish your body of the mineral. Examples of such foods include26:

    Organic bread
    Organic tofu
    Almonds
    Pecans
    Peanuts
    Spinach
    Tea (green/black)
    Pineapple
    Brown rice
    Beans (lima, pinto, navy)
    Sweet potato
    7) Eat Foods Containing Sulfur
    In addition to eating foods high in manganese, eating an organic diet rich in sulfur can help protect from glyphosate poisoning. Examples of foods with high sulfur content include the following:

    Seafood
    Eggs
    Onion and garlic
    Cruciferous vegetables (ex: broccoli, cauliflower, etc.)
    Organ meat such as liver
    Cheddar and parmesan cheese
    Veal, beef, chicken, and pork
    Nuts
    Cow’s milk
    Peaches and apricots


    Does Glyphosate Cause DNA Damage?
    So what does all of this mean? It means that the science isn’t settled yet. The effects of glyphosate on DNA and need to be investigated under controlled laboratory conditions.

    Still, there is enough evidence to be concerned about the potential devastating effects of glyphosate on your health. What’s even more concerning is that the current safety standards for glyphosate-based herbicides are simply not good enough. Many animal studies have reported that prolonged exposure to the “safe” level of glyphosate can still have adverse effects. While we wait for further research, I would highly recommend that everyone take the steps I outlined above to reduce your exposure to glyphosate.

    Now it’s time to hear from you. What steps have you taken to reduce your exposure to glyphosate? What are your thoughts on the widespread use of glyphosate in the environment? Share your thoughts in the comments below!

    Interested in a glyphosate test kit from HRI Labs? Get 10% off when you use code ‘DrJill’ at checkout. This makes the price $89.



    References:

    https://www.pnas.org/content/115/41/10305
    https://www.ncbi.nlm.nih.gov/pubmed/15012217
    https://www.mdpi.com/1099-4300/15/4/1416/htm
    https://ghr.nlm.nih.gov/primer/genef...cytochromep450
    https://www.ncbi.nlm.nih.gov/pubmed/16702333
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521964/
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392553/
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330701/
    https://www.ncbi.nlm.nih.gov/pubmed/15488650
    https://www.ncbi.nlm.nih.gov/pubmed/15908137
    https://www.ncbi.nlm.nih.gov/pubmed/15766554
    http://renewablefarming.com/images/2...yphosate-5.pdf
    https://www.ncbi.nlm.nih.gov/pubmed/18329946
    https://onlinelibrary.wiley.com/doi/...5.2010.01067.x
    https://www.sciencedirect.com/scienc...7869151530034X
    https://www.ncbi.nlm.nih.gov/pubmed/20979644
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955666/
    https://www.ncbi.nlm.nih.gov/pubmed/23000283
    https://mbio.asm.org/content/6/2/e00009-15
    https://www.ncbi.nlm.nih.gov/pubmed/27230806
    https://www.ncbi.nlm.nih.gov/pubmed/2146161
    https://www.ncbi.nlm.nih.gov/pmc/art...MC4957837/#CR1
    https://www.omicsonline.org/open-acc...25.1000256.pdf
    https://www.ncbi.nlm.nih.gov/pubmed/28987038
    https://www.ncbi.nlm.nih.gov/pubmed/18047442/
    https://lpi.oregonstate.edu/mic/minerals/manganese

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