According to Hugh Herr the augmented body parts require replacement by four years. They will have to catch up regenerative functionality of human body coming years.
How this kind of view will play with transhumanism in the future where augmented or cyborg humans will outperform natural ones in every field?
The brain acts as transceiver / receiver of information not the creator of intelligence. Memory probably exists outside of brain in the form of hyperspace field. Scientists such as Rupert Sheldrake focus on non-materialistic paradigm that drives natural evolution including human being.
Most materialistic scientists boldly claim, argue against the norm, organic body is godly, superior than synthetic ones.
In near future a human will have three choices when he/she looses limbs: (1) live as a disability person, (2) have the whole body again by attaching regenerated, organic limb, (3) becoming a cyborg with enhanced synthetic limbs.