This is another breakthrough in cancer treatments, which bypasses classic chemo-therapy that kills off many good cells.
The new technique was developed at the University of Salford, Manchester, UK - http://www.salford.ac.uk/
Applying a treatment regimen of a low cost generic doxycycline antibiotic plus the use of Vitamin C created a double punch effect to remove energy production from cancer cells, thereby "starving" the cancer cells. see: http://www.salford.ac.uk/news/articl...cer-stem-cells
How it worksCANCER stem cells, which fuel the growth of fatal tumours, can be knocked out by a one-two combination of antibiotics and Vitamin C in a new experimental strategy, published by researchers at the University of Salford, UK.
Combinational effects
First, the researchers inhibited the tumour cell mitochondria, by restricting the cancer cells only to glucose as a fuel source; then, they took away their glucose, effectively starving the cancer cells to death.
“In this scenario, Vitamin C behaves as an inhibitor of glycolysis, which fuels energy production in mitochondria, the “powerhouse” of the cell, explained co-author Dr Federica Sotgia.
The Salford team recently showed Vitamin C to be up to ten times more effective at stopping cancer cell growth than pharmaceuticals such as 2-DG, but they say that when Vitamin C is combined with an antibiotic, it is up to ten times more effective, making it nearly 100 times more effective than 2-DG.
As Doxycycline and Vitamin C are both relatively non-toxic, this could dramatically reduce the possible side-effects of anti-cancer therapy.
Clinical trials
The Salford team also identified eight other drugs that could be used as a “second-punch” after the antibiotic regime, including berberine (a natural product) – and a number of cheap non-toxic FDA approved drugs.
Professor Lisanti added: “This is further evidence that Vitamin C and other non-toxic compounds may have a role to play in the fight against cancer."
==============================
This shows also how Vitamin C deals with stopping the cancer. Folks have known Vitamin C was essential, this apparently is the reason why.
Doxycycline is derived from the very well established TetraCycline antibiotic.
TetraCycline is an "old school" antibiotic to which many organisms have developed resistance. TetraCycline is naturally produced by a soil bacteria, called streptomyces.
TetraCycline is so "old school" it was being used over 2000 years ago in Africa, by the Nubians (ref: https://www.seeker.com/ancient-nubia...766072868.html)
"In 2010 evidence was found in Africa that Human use of antibiotics began not 80 years ago, but nearly 2,000 years ago along the banks of the Nile River.
Chemical analysis of the bones of ancient Sudanese mummies who lived nearly 2000 years ago shows they were ingesting the antibiotic tetracycline on a regular basis, likely from a special brew of beer.
The find is the strongest evidence yet that antibiotics were previously discovered by humans before Alexander Fleming discovered penicillin in 1928.
"This evidence was gathered from large amounts of tetracycline (Antibiotics) embedded in the bones of ancient African mummies. Tested from the ancient Sudanese population, which lived in the Nubian kingdom (present day Sudan) between 250 A.D. and 550 A.D."
Doxycycline similarity and differences from TetraCycline -
Could possibly the naturally occurring TetraCycline plus the use of high Vitamin C fruits in Africa thousands of years ago, offered a solution to cancer, and maybe was ignored by many outsiders, and maybe used by the local informed Shaman?Doxycycline, for example, reaches the highest metabolic concentration in the eyes, whereas tetracycline concentrates primarily in body fluids.
Since tetracycline and doxycycline concentrate in different tissues, one medication might be better at fighting infections in a particular area of the body than another medication. Such differences account for both similar and varying clinical or recommended uses.
Bacterial infections such as chlamydia, Lyme disease, and anthrax benefit from treatment with either tetracycline or doxycycline.
As a prophylactic, or prevention against the spread of contagious bacterial infections like malaria and bubonic plague, doxycycline is typically more effective.
Certain travelers are often prescribed doxycycline prior to traveling to areas known for malaria infections.