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onawah
11th July 2024, 15:11
Dietary Support for the Alcoholic
Analysis by Sally Fallon Morell
July 11, 2024
https://articles.mercola.com/sites/articles/archive/2024/07/11/dietary-support-for-the-alcoholic.aspx?ui=8d3c7e22a03f5300d2e3338a0f080d2da3add85bca35e09236649153e4675f72&sd=20110604&cid_source=dnl&cid_medium=email&cid_content=art1ReadMore&cid=20240711_HL2&foDate=true&mid=DM1600147&rid=69545368

https://media.mercola.com/ImageServer/Public/2024/July/PDF/dietary-support-for-the-alcoholic-pdf.pdf
Sally Fallon Morell is author of the best-selling cookbook "Nourishing Traditions" and many other books on diet and health. She is the founding president of the Weston A. Price Foundation (westonaprice.org) and a founder of A Campaign for Real Milk (realmilk.com). Visit her blog at nourishingtraditions.com.

"STORY AT-A-GLANCE
Founder of Alcoholics Anonymous (AA), Bill Wilson advocated for nutritional therapy late in his life, noticing that eliminating sugary treats and coffee stabilized his hypoglycemia and lifted his depression, insights that AA did not adopt widely
Modern research confirms alcohol's disruption of neurotransmitters like dopamine and cortisol, crucial for mood regulation. Nutrients like vitamin B6 are pivotal in supporting these systems, potentially aiding alcoholics in recovery beyond conventional therapy
The Wise Traditions diet, rich in fat-soluble vitamins like A and D found in cod liver oil, supports neurotransmitter balance crucial for mood stability and stress resilience
Alcohol disrupts dopamine levels, leading to imbalances that perpetuate cravings. Nutritional strategies, including glycine-rich bone broth, can help restore dopamine balance, crucial for stable mood and reduced reliance on alcohol
While AA offers companionship and support, its approach overlooks crucial nutritional insights and alternative therapies explored in modern research. Addressing diet could enhance outcomes beyond spiritual and emotional support alone
This article first appeared in Wise Traditions, the quarterly journal of the Weston A. Price Foundation.

I recently learned that near the end of his life, Bill Wilson, the founder of Alcoholics Anonymous (AA), went to his board of directors and urged them to add nutritional therapy to the AA protocols. The board turned him down.

Wilson had found that coffee and sugary treats — often served at AA meetings — worsened his hypoglycemia symptoms and depression. When he removed these foods from his diet, his blood sugar stabilized and his depression cleared. He also became interested in the use of vitamin B6 for treating alcoholism. The board's decision prevented the widespread sharing of these discoveries, although his wife published a pamphlet on vitamin B6 after his death.

Today, we know a lot more about how alcohol affects the neurotransmitters that determine our outlook and moods. This knowledge indicates that vitamin B6 can indeed support the alcoholic in his recovery, but it is not the only nutrient that can help with the resolution of cravings.

Recently, a number of therapists have looked at nutritional therapy for alcoholism, including Julia Ross, author of "The Craving Cure."1 Preliminary studies indicate that a high-protein, high-fat diet, often in conjunction with vitamin or amino acid supplements, gives a success rate of 70% to 80%, compared to about 20% for conventional therapy and participation in AA.2

However, none of these therapies has focused on the principles of the Wise Traditions diet, which contains unique foods that can help the body balance the various neurotransmitters and feel-good chemicals — without drugs and perhaps even without supplements.

Neurotransmitters
New research indicates that alcohol affects the levels of many hormones and neurotransmitters in the body and brain. Chief among these are dopamine and cortisol — important stress-reducing, feel-good chemicals. Alcohol can boost these neurotransmitters temporarily, but often in ways that create imbalances and end up depressing our ability to form them naturally.

It should come as no surprise to readers of Wise Traditions that the fat-soluble vitamins play an important role in the production and regulation of dopamine and cortisol. The three key nutrients in this regard are the fatty acid arachidonic acid and vitamins A and D.

Our body makes endocannabinoids (feel-good, calming chemicals similar to those in marijuana) out of arachidonic acid, an omega-6 fatty acid found in animal fats, liver and egg yolks — the very foods the medical establishment tells us not to eat. Vitamins A and D serve as key regulators for this process.

From the endocannabinoids, the body makes dopamine and cortisol, again with the help of vitamin A. In a well-nourished individual, the body regulates the production of these compounds to relieve anxiety, lift the mood and support motivation — that is, the kind of focused, goal-oriented behavior that creates true happiness and reduces the need for stimulants and drugs.

Another key neurotransmitter affected by alcohol is serotonin. Low serotonin results in numerous conditions that can predispose to alcoholism, including anxiety, depression, impulsive behavior, irritability, low self-esteem, sleep problems and post-traumatic stress disorder.

The production of serotonin requires the amino acid tryptophan, vitamin D, iron, magnesium and calcium, vitamin C and B vitamins. Alcohol can temporarily raise serotonin levels, but at the same time it depletes the nutrients (like B6 and folate) needed to produce serotonin naturally.

Trauma can affect natural serotonin levels. For example, a 2009 study3 found that participants who had experienced childhood abuse had lower brain serotonin transporter binding potential than those who were not abused, meaning that they had lower serotonin activity than needed to maintain a happy and optimistic mood. Other traumatic experiences, such as the danger of war or loss of a job or loved one, can be expected to trigger similar disruption of endogenous serotonin production.

Let's look at the components of the Wise Traditions diet to ascertain how they might help the alcoholic discover that he doesn't actually need to drink anymore.

Egg Yolks
Egg yolks are the best source of cholesterol in the human diet. All adrenal hormones are made with cholesterol, with the help of vitamin A. Egg yolks are not only a great source of vitamin A but also of vitamins D, K2, B6 and B12, along with iron and sulfur as well as arachidonic acid, from which the body produces endocannabinoids.

Alcohol increases dopamine levels — sometimes called the body's natural cocaine — but in a way that can cause a serious imbalance. Alcohol can provide a temporary pep-up, but as the mechanism for dopamine regulation becomes exhausted, that pep-up may be harder to achieve.

https://media.mercola.com/ImageServer/public/2024/July/alcohol-dopamine-levels.jpg

In the words of Brick, the famous alcoholic son of Big Daddy in Tennessee William's play Cat on a Hot Tin Roof, that pep-up becomes "dilatory."

Gelatin-rich bone broth provides a natural way to regulate dopamine,4 bringing it up to a healthy level while preventing dopamine from becoming too high (in which case we become manic). Bone broth also provides glutamic acid, which the body uses to produce GABA, the "calming" amino acid often recommended in supplement form by Julia Ross and others.

https://media.mercola.com/ImageServer/Public/2024/June/alcohol-and-vitamins.jpg

A mug of genuine bone broth morning and evening can serve as the alcoholic's best friend, providing key nutrients for neurotransmitters and calming feel-good chemicals.

However, beware of substitutes — broth made from bouillon cubes, cheap soup made from powdered "bases," broth in cans or aseptic packaging and any processed food to which MSG in all its guises is added — in other words, all processed foods. MSG works very differently in the body compared to the natural glutamic acid in real broth.

By the way, another — and surprising — source of GABA besides glutamic acid is putrescine,5 a stinky amino acid that occurs in fermented meat and fish products (popular in Asia) and stinky cheeses (popular in Europe). Fermented cod liver oil also contains small amounts of putrescine.

Raw Animal Foods
People in traditional cultures consumed some animal foods raw, a practice that is rare in modern cultures and especially in America. Raw animal foods provide our best source of vitamin B6, necessary for the formation of the various neurotransmitters affected by alcohol consumption. Alcoholics tend to be deficient in B6, in part because this vitamin is involved in clearing alcohol from the body through the liver.

Vitamin B6 is rapidly destroyed by heat but is fully intact in raw animal foods such as raw meat dishes like steak tartare or carpaccio, or raw dairy products — raw milk, raw kefir, raw yogurt and raw cheese. In addition to B6, raw dairy foods provide calcium in highly assimilable form, a mineral that is critical to the formation of serotonin and dopamine. The recovering alcoholic needs to consume raw animal foods every day.

Liver
Liver is the most nutrient-dense food in the human diet and provides a host of compounds that help us deal with stress, produce important neurotransmitters and nourish every system in the body. Poultry liver is best because of its great balance of A, D and K2. The best way to eat liver is as paté or liverwurst several times per week.

For those who can't learn to like liver, desiccated liver capsules are a good substitute. Another way to consume liver is to cut organic or pasture-raised chicken liver into pea-sized pieces, freeze them and swallow them like vitamin pills. Desiccated or frozen liver to provide one-half to one ounce of liver per day is a good maintenance dose.

Animal Fats
Even those who recommend a high-fat diet for alcoholics tend to shy away from advocating animal fats. Instead, they suggest loading up on olive oil and coconut oil. But these oils do not contain the key nutrients we get exclusively from animal fats, namely arachidonic acid and the fat-soluble vitamins A, D and K2.

As already noted, arachidonic acid serves as a precursor for endogenous cannabinoids (the calming, feel-good neurotransmitters). There is only one source for the body to get adequate arachidonic acid and that is from fatty animal foods like butter, lard, egg yolks, liver and meat fats.

There is another reason to eat animal fats: they supply 18-carbon saturated fatty acids, which support hormone production and cell-membrane integrity. The body needs these saturated fats and needs a lot of them. If we refuse to eat animal fats, the body has a back-up plan: it makes them from refined carbs.

The best way to get rid of cravings for refined carbs and avoid the blood sugar roller coaster that often also leads to cravings for alcohol is to eat plenty of animal fats. So eat your meat with fat, load up on eggs (especially the yolks), enjoy full-fat cheese, eat bacon for breakfast and put butter on everything!

Unrefined Salt
The adrenal glands require salt, especially in times of stress. Chlorine from salt is needed for protein digestion and is involved in the production of many neurotransmitters, including GABA. Further, unrefined salt contains a wealth of trace minerals, all with important roles to play in maintaining optimal health and freedom from cravings.

Fermented Foods
Fermented foods like sauerkraut supply beneficial bacteria to the digestive tract, and these bacteria produce many of the same feel-good chemicals that originate in the brain.6 In addition, fermented foods are a great source of vitamin C — raw sauerkraut is ten times richer in vitamin C then raw cabbage. Vitamin C supports the adrenal glands in times of stress and assists in the production of serotonin.

Additional Help
There are many homeopathic remedies that can help the alcoholic resist alcohol and even develop an aversion to beer, wine and distilled liquors. Herbal remedies can also be effective. It may require some trial and error to find the right remedies, but the effort can pay off with important benefits.

Even allopathic medicine has a role to play. Going off alcohol cold turkey can provoke serious reactions, such as seizures. Anti-seizure medications are available to lessen the danger. Before attempting to withdraw from alcohol, it is essential that you consult a medical professional. Alcohol withdrawal can be life-threatening.

What Alcoholics Anonymous Overlooks
AA's stated purpose is to enable its members to "stay sober and help other alcoholics achieve sobriety." Since 1935, when alcoholic Bill Wilson founded the organization, AA has grown into an international self-help group with over two million members.

To share their method, Wilson and other members wrote "Alcoholics Anonymous: The Story of How More Than One Hundred Men Have Recovered from Alcoholism," from which AA drew its name. It outlines a twelve-step program in which members admit that they are powerless over alcohol and need help from a "higher power."

They seek guidance and strength through prayer and meditation from God or a higher power of their own understanding; take a moral inventory with care to include resentments; list and become ready to remove character defects; list and make amends to those harmed; continue to take a moral inventory; pray and meditate; and try to help other alcoholics recover.

The goal is to create enough change in the alcoholic's thinking "to bring about recovery from alcoholism" through a spiritual awakening. AA meetings are "quasi-ritualized therapeutic sessions run by and for alcoholics."

Does AA work? Certainly, the meetings provide companionship and support for alcoholics, but studies of AA's efficacy have produced inconsistent results. While some studies suggest an association between AA attendance and increased abstinence or other positive outcomes, others do not. Reports have varied from a 75% success rate to negative outcomes. Researchers are hampered by the difficulty in measuring success rates.

The biggest failing of AA, however, is the fact that the organization does not provide information on diet and alternative therapies to alcoholics. Typical offerings of donuts and coffee at AA meetings are the worst possible snacks for the recovering alcoholic. Nor does AA keep abreast of all the modern research on alcoholism and its effects on neurotransmitters.

At the same time, despite what recent research has revealed about the association of alcoholism and neurotransmitters, it is incorrect to imply that alcoholism is merely a problem with brain chemistry. There is also an emotional and spiritual component to alcoholism, and it is the alcoholic who must take the first step — who must say, "I want to change." But once that step is taken, the Wise Traditions dietary recommendations can be of immense help along the path to sobriety.

What Is the Wise Traditions Diet?
The pioneering work of Dr. Weston A. Price determined that the basic characteristic of optimal human diets was nutrient density.

The diets of healthy human beings — free of dental problems, degenerative disease and mental illness, and highly resistant to infectious disease — contained minerals at levels at least four times higher than the American diet of his day and fat-soluble vitamins (vitamins A, D and K2) at levels at least ten times greater than the American diet of his day.

"Sacred" foods rich in these fat-soluble vitamins included liver and other organ meats; whole raw dairy foods, especially butter, from ruminant animals on pasture; egg yolks from pastured poultry; animal fats; fish eggs; fish livers and fish liver oil; and shellfish.

In addition, preparation techniques such as fermentation, cooking of gelatinous bone broth and long soaking and souring of grains transformed hard-to-digest foods into foods from which the nutrients were readily available. The Wise Traditions diet — one that incorporates these principles in modern times — should always serve as the preliminary therapy for every type of health problem, including alcoholism.

Alcohol's Complex Effects
Because alcohol is a small molecule, it interacts with many neurotransmitter systems in the brain and nervous system; this makes the action of alcohol more complex than that of large molecules such as opiates or amphetamines, which tend to stimulate only one specific neurotransmitter.

GABA — Gamma-aminobutyric acid (GABA) is the chief inhibitory neurotransmitter in the central nervous system. Its principal role is reducing excitability. Alcohol affects the GABA system in a manner similar to valium, leading to relaxation and drowsiness.

Dopamine — Alcohol is a particularly lethal toxin to the dopamine system, one that attaches itself to the dopamine neurotransmitter and triggers compulsion.

Endorphins — Alcohol affects the endorphin system in a manner similar to opiates, acting as a pain-killer and giving an endorphin "high."

Glutamate — Alcohol's effects on the glutamate system lead to staggering, slurred speech and memory blackouts.

Norepinephrine — Alcohol causes a release of norepinephrine (also known as noradrenalin) in the brain, which is one reason why alcohol acts as a stimulant and not just as a depressant. As a stimulant, alcohol peps you up, but as a depressant alcohol can trigger depression.

Adrenaline — Alcohol causes the adrenal glands to release adrenaline. This is another reason why alcohol has stimulant properties. The release of adrenaline stimulates the "fight or flight" response, which then calls for the calming "rest and digest" adrenal cortex hormones. Constant stimulation of adrenaline — which happens in spades when alcohol is combined with coffee — can lead to adrenal exhaustion.

Instead of Alcohol
What does the recovering alcoholic drink with meals? What does he take that is more refreshing and more enjoyable than beer, wine or whiskey? Why, kombucha, of course! Therapists may warn against kombucha because it contains a small amount of alcohol — 0.5% or less — but the same is true of fruit juices.

And if the recovering addict continues to eat sugar and refined carbs, he will make small amounts of alcohol out of those. Kombucha may indeed be a problem if it is too sweet, so look for brands that contain less than five grams of sugar per serving. Even better, make your own7 to ensure that it is sufficiently sour.

Another great beverage with meals is a vinegar drink made with raw apple cider vinegar plus sparkling water, and maybe a squeeze of lemon or lime.

Herbal Treatments for Alcoholism
The use of herbs to treat alcoholism dates back thousands of years. Those in the process of renouncing alcohol can determine their effectiveness on a trial-and-error basis. However, exercise care when buying extracts, tinctures and essences to ensure that they do not contain alcohol. Alcohol is commonly used as an aid to extract the active elements of an herb. Be sure to read labels carefully!

Kudzu, an Asian root, is attracting considerable interest for the treatment of alcoholism. Studies have indicated that test animals drink less alcohol than controls when given kudzu root. Studies with humans give mixed results. Kudzu seems to lessen the amount that nonalcoholic people drink, but it does not reduce cravings in alcoholics. And a word of caution: the active ingredients in kudzu are diadzin and daidzein — estrogen-like compounds similar to those in soy.

St. John's wort can help alleviate depression, as shown in many studies. Because alcoholism and depression often go hand in hand, St. John's wort is a natural choice for supporting those struggling with alcoholism. As with kudzu, those who take St. John's wort tend to drink less than they otherwise would.

Milk thistle can be helpful in the treatment of liver dysfunction. The seeds contain a compound called silymarin, which helps to cleanse the liver of poisons. Those undergoing alcoholism detox often receive milk thistle to help rid the liver of alcohol. However, silymarin is not effective with severe liver damage, such as alcoholic hepatitis or alcoholic cirrhosis.

Passion flower is the herbal treatment of choice for opiate withdrawal, helping to relieve nausea. Research indicates that the herb can also help with alcoholism detox and the associated withdrawal symptoms.

Ginseng is valued for its revitalizing and energizing qualities. Its main effect is to increase the metabolism, thus helping the body break down alcohol more quickly and aiding in detox. Be sure to purchase pure ginseng — many products contain fillers that greatly dilute its effects.

Cayenne pepper is a great tonic for the stomach. Those who drink too much alcohol tend to suffer from stomach problems and, in particular, gastritis. Cayenne pepper relieves the pain and reduces the inflammation of the stomach lining that is caused by excessive alcohol consumption. Be sure to purchase cayenne pepper powder that is organic.

Dopamine Balance — Broth to the Rescue
Dopamine is an important "feel-good" neurotransmitter. In well-adjusted individuals, two types of dopamine — tonic and phasic — work together in balance to provide both stability (tonic) and flexibility (phasic) to our mental processes. In addition to the arachidonic acid and vitamins A and D required for the production of dopamine, we need various nutrients for the activation and balance of its tonic and phasic forms.

Alcohol disrupts the delicate dopamine balance. In the long run, heavy consumption of alcohol can lead to overproduction of tonic dopamine, resulting in an even greater need for alcohol to achieve a calming effect and a temporary lift in mood. In other words, the increase in tonic dopamine levels leads to cravings for alcohol to restore production of phasic dopamine.8

The process of methylation is involved in the activation of tonic dopamine. A methyl group is simply one carbon attached to three hydrogens (CH3); this tiny molecule can act as a switch, turning chemicals on or off in the body. The methylation of dopamine results in the production of tonic dopamine, which provides mental stability.

However, too much methylation can cause a higher level of tonic dopamine than required, leading to a state of distractibility and hyperarousal.

Hypermethylating individuals often tend to be highly creative and energetic, but also display symptoms that may include anxiety, depression, panic attacks, attention-deficit/hyperactivity disorder (ADHD), sleep disorders, restlessness, histamine intolerance, sensitivity to environmental toxins and schizophrenia.

The flexibility supported by phasic dopamine allows us to deal with difficult situations with patience and calm, but hypermethylation blocks the production of phasic dopamine.9

Because the amino acid methionine and animal-food vitamins B6 and B12 are required for dopamine methylation, practitioners may advise those suffering from symptoms of hypermethylation to switch to a plant-based diet — even though many plant foods, especially legumes, also contain methionine.

While a meatless diet may help temporarily, it can lead to deficiencies in the long run and even symptoms of undermethylation, including pathological inflexibility and brittle mental states.

The key in helping alcoholics restore balance between the tonic and phasic dopamine systems is the amino acid glycine, which blocks hypermethylation. Although pharmaceutical companies have proposed a number of drugs to dampen down hypermethylation, why not just use bone broth, our best food-based source of glycine?

Those treading the difficult path of alcoholism recovery will find a true friend in bone broth, known for its calming effect. A cup of warm bone broth (seasoned with unrefined salt) should accompany every meal — especially meals containing meat — or serve as an ingredient in gravies and sauces."

https://media.mercola.com/ImageServer/public/2024/June/alcohol-stability-flexibility.jpg


- Sources and References
1 Amazon, Ross J. The Craving Cure: Identify Your Craving Type to Activate Your Natural Appetite Control. Flatiron Books, 2017
2 HealthyPlace, Nutrition Therapy for Treating Alcoholism
3 Synapse. 2009 Jul;63(7):565-73
4 Masterjohn C. The Pursuit of Happiness. Wise Traditions 2008;9(4):14-24
5 Neuroscience. 2007 May 11;146(2):489-93
6 Medium, Chris Carr, The Surprising Link Between the Brain, Gut Bacteria, and Anxiety
7 Nourishing Traditions, Kombucha Like Fine Champagne
8, 9 Addiction. 2000 Aug:95 Suppl 2:S119-28

thalox
11th July 2024, 16:22
Wow thanks for the good info. It’s funny I haven’t been here for a bit and decided to read some posts and the first one that popped up for me is this one as I am on my journey to rid alcohol from my life. Thanks for this. Hits close to home.

I am have not been craving alcohol for a few days as I try to keep myself busy but as the weekend approaches; this will be the true test as pretty much every weekend I have some drinks. I will try to find out what else I can do to pass the time.


I noticed that when I drink time flies, but when I am sober time slows down and I get bored and my brain wanders.


I do like the concept of drinking bone broth.

gord
11th July 2024, 17:42
All of the above information from Onawah is excellent. I started with "The Vitamin Cure for Alcoholism: Orthomolecular Treatment of Addictions" by Abram Hoffer and Andrew W. Saul, which I didn't see mentioned here, and is one of a series of 13 similar books by Hoffer and Saul.

onawah
15th September 2024, 01:42
What Does the Science Say About Alcohol Consumption?
Analysis by Dr. Joseph Mercola
September 14, 2024
https://articles.mercola.com/sites/articles/archive/2024/09/14/alcohol-consumption-science.aspx?ui=8d3c7e22a03f5300d2e3338a0f080d2da3add85bca35e09236649153e4675f72&sd=20110604&cid_source=dnl&cid_medium=email&cid_content=art1ReadMore&cid=20240914&foDate=true&mid=DM1629882&rid=118939609

https://media.mercola.com/ImageServer/Public/2024/September/PDF/alcohol-consumption-science-pdf.pdf

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Story at-a-glance
Alcohol consumption, even at low levels, can negatively impact brain structure, reducing overall brain volume and affecting gray and white matter integrity
Ethanol in alcoholic drinks is converted to acetaldehyde, a toxic substance that damages cells indiscriminately, leading to various health issues including increased cancer risk
Alcohol disrupts gut health by killing beneficial bacteria, potentially causing leaky gut syndrome and triggering inflammatory responses that affect your liver and brain
Regular alcohol consumption can alter hormonal balance, increasing estrogen levels and potentially raising cancer risk, especially for breast cancer
While N-acetylcysteine (NAC) supplementation may help mitigate some harmful effects of alcohol, abstaining completely is the safest option for optimal health

In the Everyday Wellness podcast above, Brooke Scheller, a doctor of Clinical Nutrition, founder of Functional Sobriety (a nutrition-based program for alcohol reduction) and author of "How to Eat to Change How You Drink," discusses the impact of alcohol on your brain and body. I recently interviewed Brooke and will have her interview up in the next few weeks.

While I don’t recommend drinking alcohol, historically humans have been consuming it for thousands of years, including for recreational and medicinal purposes. The first instance of alcohol distillation can be traced back to China in the 1st century,1 while alcohol has served various purposes throughout history:

1.Nutritional — Some cultures believed, and some still do, that alcohol provides valuable calories, though they’re actually "empty calories."

2.Medicinal — Alcohol's ability to kill bacteria made it useful for medical purposes. However, it also destroys beneficial gut bacteria, potentially leading to issues like leaky gut syndrome.

2.Recreational — The primary reason for alcohol consumption has been to alter one's mental state. Many people seek the feeling of intoxication, despite the subsequent negative effects such as decreased happiness, motivation and increased stress.

Are Small Amounts of Alcohol Bad for Your Brain?
It’s often suggested that while heavy alcohol consumption is harmful, small or moderate amounts may provide some benefits. However, evidence suggests that alcohol consumption, even at low levels, may carry more risks than benefits for overall health.

According to a study from the UK Biobank that examined brain scans of 36,678 middle-aged and older adults,2 even just one to two alcoholic drinks per day is associated with negative changes in brain structure, including reductions in overall brain volume, gray matter and white matter integrity.

The brain consists of two main types of tissue: gray matter and white matter. Gray matter comprises neuron cell bodies, which contain the cells' genetic material. White matter, on the other hand, is made up of axons - long fibers extending from neurons. These axons are coated with a fatty substance called myelin, giving white matter its characteristic appearance.

This myelin sheath enables rapid communication between nerve cells, facilitating efficient information transfer throughout the brain.

The study demonstrates that the negative effects on brain structure are not limited to heavy drinkers but are observable even at low levels of alcohol intake. As consumption increases, so does the severity of these structural changes. This research provides compelling evidence that there may be no "safe" level of alcohol consumption when it comes to brain health.

A review published in Frontiers in Neuroscience also addressed the complex interplay between alcohol consumption and cognitive decline, noting that chronic alcohol abuse leads to "changes in neuronal structure caused by complex neuroadaptations in the brain."3

Alcohol Is Converted Into the Poison Acetaldehyde
Ethanol, the type of alcohol in drinks, is both water-soluble and fat-soluble. This allows it to easily pass into all cells and tissues of your body. When ingested, ethanol is converted to acetaldehyde, which is a well-known poison that indiscriminately damages and kills cells. Your body then converts acetaldehyde to acetate, which can be used as fuel. However, this process is metabolically costly and provides no real nutritive value.

When you consume alcohol, it enters your stomach, then your liver starts converting the ethanol to acetaldehyde and then to acetate. Some of these byproducts reach your brain by crossing the blood-brain barrier (BBB).

The blood-brain barrier (BBB) is a protective mechanism that prevents most substances from entering the brain. However, alcohol is an exception due to its unique property of being both water- and fat-soluble. This characteristic allows alcohol to easily penetrate the BBB and enter the brain tissue.

Once inside, alcohol interacts with and affects the brain's internal environment, which is primarily composed of two major cell types: neurons (nerve cells) and glial cells (found between neurons). The presence of alcohol in the brain disrupts normal neural circuit function, leading to the various effects associated with intoxication.

Among alcohol’s effects is suppression of activity in the prefrontal cortex, a brain area involved in impulse control and decision-making. As alcohol suppresses prefrontal cortex activity, people become more impulsive and less inhibited.

What’s less known, however, is that alcohol-induced changes in neural circuits can persist long term, even if you don’t drink heavily. Drinking patterns like having one or two drinks per night or drinking only on weekends, for instance, can lead to changes in the brain's circuitry for habitual and impulsive behavior. These changes can continue even when not drinking, potentially making people more impulsive in their daily lives.

Fortunately, these changes are not permanent in most cases. A period of abstinence, typically ranging from two to six months, can allow these neural circuits to return to their normal state. The exception is in cases of chronic, heavy alcohol consumption over many years, where the changes may be more persistent.

It's also important to distinguish between being "blackout drunk" and passing out. During a blackout, an individual may still be active and conscious, but their hippocampus — a brain region crucial for memory formation — is temporarily impaired. This results in an inability to form new memories, leading to no recollection of events the following day, despite the person having been awake and functional during that time.

Alcohol Damages Your Gut Health
Alcohol negatively affects your gut microbiome and gut-liver-brain axis, a bidirectional communication network that links these three crucial systems in your body. Alcohol's antimicrobial properties, which make it effective for sterilization, also indiscriminately kill beneficial gut bacteria.

For instance, alcohol consumption may decrease Akkermansia muciniphila, a beneficial bacterial species naturally found in the human gut.4 This, in turn, is associated with "dysregulation of microbial metabolite production, impaired intestinal permeability, induction of chronic inflammation, and production of cytokines."5

The metabolism of alcohol in your liver also triggers a proinflammatory response, releasing cytokines such as IL-6 and tumor necrosis factor alpha. This inflammatory reaction, combined with the disruption of gut bacteria, can lead to a condition known as "leaky gut." In this state, harmful bacteria from partially digested food can escape your gut and enter your bloodstream.

The simultaneous occurrence of good bacteria die-off and bad bacteria infiltration creates a "two-hit" model, where the combined effects are more severe than each issue individually. These gut and liver disturbances have far-reaching consequences, Huberman explains, particularly on your brain.

Through neuroimmune signaling, inflammatory molecules can cross your blood-brain barrier, disrupting neural circuits that regulate alcohol consumption. Paradoxically, this disruption often results in increased alcohol intake, creating a vicious cycle of gut microbiome disruption, liver inflammation and altered brain function.

This self-perpetuating process explains why regular drinkers, even those who don't consume large quantities, may find themselves caught in a pattern of increasing alcohol consumption and worsening systemic inflammation.6

Meanwhile, pathogenic oxygen-tolerant bacteria secrete a very virulent form of endotoxin, also known as lipopolysaccharides (LPS), which can cause inflammation if they translocate across the compromised gut barrier into the systemic circulation.

Even one episode of binge drinking results in increased endotoxin levels, "likely due to translocation of gut bacterial products and disturbs innate immune responses that can contribute to the deleterious effects of binge drinking," researchers wrote in PLOS One.7

A study published in Scientific Reports also found that excessive drinkers had an increase in levels of LPS,8 while, among alcohol-dependent adults, avoiding alcohol for 19 days led to significant reductions in gut permeability.9

Even Light Drinkers May Be at Risk of Premature Death
A systematic review and meta-analysis of 107 cohort studies involving more than 4.8 million people revealed that drinking less than two drinks a day is not associated with reductions in risk of all-cause mortality.10 Further, drinking more than this may significantly shorten life expectancy.

The study’s lead author, Tim Stockwell, a scientist with the Canadian Institute for Substance Use Research, told the Daily Mail that drinking about two drinks per week over your lifetime may cut your life short by three to six days. Drinking seven drinks a week may shave 2.5 months off life expectancy, while consuming about 35 drinks per week may reduce lifespan by about two years.11

One reason for this detrimental effect could be alcohol's link to cortisol. Regular alcohol consumption, even at moderate levels, can lead to changes in the hypothalamic-pituitary-adrenal (HPA) axis.

This alteration in the HPA axis can result in higher baseline cortisol levels when not drinking. In other words, individuals who drink regularly may experience elevated levels of cortisol, often referred to as the "stress hormone," even during periods when they are not consuming alcohol. This persistent increase in baseline cortisol can have various negative impacts on overall health and well-being.

This means that regular drinkers may actually feel more stressed and anxious when they're not consuming alcohol. Further, while cortisol plays a vital role in your health, it can lead to severe health issues like muscle breakdown, inflammation and impaired immune function when chronically elevated, which is why keeping your levels in check is so important.

Alcohol Increases Estrogen Levels and Cancer Risk
Drinking alcohol affects your hormones, particularly the balance between testosterone and estrogen. Alcohol tends to increase the conversion of testosterone to estrogen,12 which can have various negative effects in both men and women. Estrogens are one of the primary factors contributing to increasing your cancer risk.

Alcohol also increases cancer risk via acetaldehyde toxicity, which can cause DNA damage, inflammation, leaky gut and weakened immune function. Drinking alcohol also disrupts sleep, which means you’re not getting a restorative night’s sleep when you drink. Further, acetaldehyde toxicity can alter DNA methylation and gene expression, which raises your cancer risk as well.

How to Mitigate Some of Alcohol’s Harmful Effects
I don’t recommend drinking alcohol, and the best way to avoid its harmful effects is to simply not drink it. If you do plan to have an alcoholic beverage, however, N-acetylcysteine (NAC) supplementation can be used as a preventive measure when taken beforehand. NAC is a derivative of the amino acid cysteine, which not only boosts glutathione levels but also helps mitigate acetaldehyde toxicity, a primary cause of hangover symptoms.

Taking at least 200 milligrams of NAC about 30 minutes before drinking may help reduce alcohol's toxic effects. The efficacy of NAC is thought to be enhanced when combined with vitamin B1 (thiamine). Additionally, vitamin B6 may help alleviate hangover symptoms.

Since alcohol consumption depletes B vitamins, which are necessary for alcohol elimination from your body, taking a B vitamin supplement before and after drinking can be beneficial. However, it's crucial to note that this approach does not protect against alcohol poisoning or other serious risks associated with excessive drinking.

Therefore, it's essential to consume alcohol responsibly and in moderation, regardless of any preventive measures taken. For optimal health, however, consider avoiding alcohol completely and instead exploring alternative methods for stress reduction and social interaction that don't involve drinking."

- Sources and References
1 YouTube, Andrew Huberman, What Alcohol Does to Your Body, Brain & Health August 22, 2022, 10:52
2 Nature Communications, Volume 13, Article number: 1175 (2022)
3 Front. Neurosci., 05 July 2019
4, 5 Molecular Nutrition & Food Research
6 YouTube, Andrew Huberman, What Alcohol Does to Your Body, Brain & Health August 22, 2022, 55:12
7 PLOS One May 14, 2014
8 Scientific Reports, Volume 7, Article number: 4462 (2017)
9 PNAS October 6, 2014
10 JAMA Network Open March 31, 2023
11 The Hill July 9, 2024
12 Alcohol November 2000, Volume 22, Issue 3, Pages 123-127

RMF808
15th September 2024, 04:48
No doubt removing alcohol and sugars from your life allow the human body to work better but through working in the bar scene for 15 years I have found that most who drink don’t want to quit or can’t. It’s beyond a physical craving but an escape from their minds.

Finding peace within would help deter alcoholism but this is a problem far bigger than just alcohol. The problem is sugar and the Atkins diet.breakfast cereals, sodas, yogurt, coconut water on & on. If and when people decide to go sugar free, the options we have are aspartame, sucralose and a few other chemicals that do even worse things to our body like cancer & pineal gland calcification. Buuut, that is going to need to find another thread.


The Atkinson diet says that carbs are the devil and people just eat it up. A huge problem with this is that fiber is a carbohydrate and it helps regulate sugar uptake into our cells. Working like a door guy at a bar or a ticket checker at a concert. Rather than allowing everyone just rush into the venue, there is a cadence developed by being checked at the door.


Ask any doctor or just search some research sites like NCBI, PubMed etc and all the info is there. I came across this wondering about which people had the longest lifespan on the planet. I found that it was the people of Okinawa and they were out gardening at over 100 years old. Even though they got 70% of their daily caloric intake from carbohydrates.

They eat what they grow without processing the fiber out of it. Just like any white bread, white rice, white tortillas all have the fiber (carbs) removed from the food. Leading to obesity and diabetes.

I didn’t just read something online and regurgitate it, I put it into practice with my 84 year old grandmother who had diabetes for 50 years. She didn’t want to change because she always had candy in her purse. She was a child of the depression and gained an affinity for sweets. Rather than making her quit eating what she liked, I found out what could help regulate what she was already doing. People do t want to change deep down.

After my super secret methods, she went to her doctor of 22 years and he had some “faulty test results”. They ran the tests 3 times and they all came back showing she no longer had diabetes. He recommended going to another doctor and he ran the test twice. Both showing no diabetes.

The secret was chia seeds… She was still sneaking her candy bars all the while I was adding chia seeds to salads, banana mango smoothies, chocolate chia pudding and more. That simple addition of fiber to her diet began to help her body regulate the sugar rush into her system. Also, for every ( I forget the exact number 1/2g or 1g) gram of fiber she ate, she was supposed to reduce the amount of insulin she was taking in half. She wasn’t even considering fiber when calculating how much insulin to give herself.

When I told them to ask the doctor, he confirmed this. Apparently, he had forgotten to mention any of this in all of his years treating her but seemed to have the answer when the question was asked.

He got paid to keep her on insulin using all of the diabetic garb like needles, meters, internal regulation modules etc.

Though she dealt with all of the finger pricks for over 50 years, she died with no diabetes.

The End….

…Or is it just the beginning for you & yours?

onawah
15th September 2024, 08:39
Raw organic honey is a wonderful sweetener, and has many health benefits.

If and when people decide to go sugar free, the options we have are aspartame, sucralose and a few other chemicals that do even worse things to our body like cancer & pineal gland calcification. Buuut, that is going to need to find another thread.

onawah
3rd October 2024, 03:11
Why Even ‘Moderate’ Drinking Is Harming Your Health
Analysis by Dr. Joseph Mercola
September 29, 2024
https://articles.mercola.com/sites/articles/archive/2024/09/29/alcohol-moderate-drinking.aspx?ui=8d3c7e22a03f5300d2e3338a0f080d2da3add85bca35e09236649153e4675f72&sd=20110604&cid_source=dnl&cid_medium=email&cid_content=art1ReadMore&cid=20240929&foDate=true&mid=DM1637074&rid=130062611

https://media.mercola.com/ImageServer/Public/2024/September/PDF/alcohol-moderate-drinking-pdf.pdf

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"Story at-a-glance
Moderate alcohol consumption, once thought to be harmless or even beneficial, is now recognized as detrimental to health, with no safe level of alcohol consumption
Alcohol negatively impacts multiple bodily systems, including mitochondrial function, gut health, hormone balance and nutrient levels. It significantly increases cancer risk, contributing to 1 in 3 cancers
The alcohol industry's "moderation" guidelines are misleading. If Americans followed these, alcohol sales would drop by 70% to 80%. Overconsumption is widespread
A growing "sober curious" movement recognizes the benefits of reducing or eliminating alcohol consumption. About 41% of Americans are currently looking to quit or cut back
Strategies for reducing alcohol intake include education, community support, addressing root causes, nutritional support and reframing your relationship with alcohol as a positive health choice
I've had many eye-opening moments that have shifted my understanding of what truly contributes to wellness and longevity. Recently, I had one such revelation about a substance many take for granted as being relatively harmless, or even beneficial, in moderation: alcohol.

I interviewed Dr. Brooke Scheller, a doctor of clinical nutrition, founder of Functional Sobriety (a nutrition-based program for alcohol reduction) and author of "How to Eat to Change How You Drink," who has done extensive research on the health impacts of alcohol consumption.

We discuss how misguided and dangerous the common beliefs around "moderate" drinking really are. I'm compelled to share these insights with you, as I believe this information could be transformative for your health.

The Myth of ‘Healthy’ Moderate Drinking
Many believe that having a glass of wine with dinner or a cocktail to unwind is not only acceptable but even good for health. Red wine has been touted for its antioxidants, and studies have suggested moderate drinkers live longer than both heavy drinkers and teetotalers. Scheller and I discussed how deeply flawed and misleading this research is:1

"There's now more studies, larger body studies that are showing that the small amounts, the ‘moderate’ amount of alcohol that we previously thought was providing some benefit, we're looking at those studies now and saying those were flawed studies.

The control group of folks that they were using who were non-drinkers were either non-drinkers because they previously had an alcohol issue or they were non-drinkers because they already had preexisting health conditions like cardiovascular disease."

In reality, there is no safe level of alcohol consumption when it comes to your health. Every drink causes damage to your body on a cellular level. As Scheller emphasized:2

"My perspective is that no amount of alcohol is the safest, and I think that even one drink per day is having an effect on your health. And if you are someone who is diabetic, pre-diabetic, you have cancer, increased risk for cancer, if you have an autoimmune condition, if you have hormone imbalances, GI issues, that one drink is affecting those symptoms.

I do think that even at the lowest amounts that you could be consuming it, if you are looking to optimize health, the answer is none."

The Widespread Impact of Alcohol on Health
Alcohol's negative effects are pervasive throughout the body. Beyond liver damage and the risks of intoxication, alcohol:

Impairs mitochondrial function,3 accelerating aging

Disrupts your gut microbiome4

Depletes crucial nutrients

Impacts hormones like leptin and ghrelin

Increases cancer risk dramatically5

Contributes to insulin resistance and metabolic dysfunction6

Exacerbates anxiety and depression

Scheller pointed out that alcohol plays a much bigger role in many chronic health conditions than many currently recognize:7

"I think that alcohol consumption is playing a much larger role in societal health concerns than we are really able to understand right now. And some of that is under-reporting and people, again, not really recognizing how much alcohol maybe they're having, doctors maybe not asking their patients how much alcohol they're consuming."

One of the most alarming statistics Scheller shared is that alcohol may contribute to 1 in 3 cancers — and she believes this estimate could even be low:8

"I agree that I think that number might actually be higher, that it might be more than 1 in 3. Again, depending on how much people are consuming this ... We know that alcohol is linked to cancers where there's direct impact of alcohol, so mouth, throat, esophageal, colon cancer, but also hormone-specific cancers like breast cancer."

This cancer risk exists even at low levels of consumption, again highlighting that there is no "safe" amount when it comes to alcohol and cancer risk.

To understand why alcohol is so harmful, you need to look at what happens in your body when you drink.

Processing alcohol uses a lot of energy. This can deplete vital nutrients and cofactors. This energetic demand places significant strain on your body’s resources, impacting your health. Also, this process creates harmful byproducts. One is acetaldehyde, a toxic compound that can damage cells. This not only affects the cells directly but also has broader implications for the body’s physiological balance.

The disruption affects the endocrine system. It can imbalance hormones and blood sugar levels. These imbalances can cause mood swings and energy spikes and crashes. They can also lead to long-term health issues like diabetes and thyroid dysfunction. Furthermore, your liver, which plays a critical role in detoxifying harmful substances, can become impaired.

When your liver is overwhelmed, its efficiency in processing other toxins diminishes, which can lead to an accumulation of toxins in the body.

Moreover, the impact extends to your gastrointestinal tract. The damage to your gut lining and the disrupted microbiome harm digestive health and immune function. The microbiome is the complex community of microorganisms in the digestive system. It can cause digestive issues, infections, and long-term health problems. The effects of processing challenging substances highlight the need for mindful consumption. We also need good nutrition to stay healthy.

Further, alcohol produces similar damaging compounds to excessive omega-6 fats, like linoleic acid. When they're metabolized, they turn into something called OXLAMs, which is oxidized linoleic metabolites. And what's consistent with all of those molecules is they're reactive aldehydes.

Alcohol turns into a reactive aldehyde, which is called acid aldehyde, and these reactive aldehydes wreak havoc throughout your body, damaging mitochondria and accelerating aging at a cellular level.

The Unrecognized Epidemic of Alcohol Overconsumption
Problematic drinking is also prevalent in our society. Scheller shared some startling statistics:9

"If alcohol was consumed in moderation — like the alcohol industry puts that little disclaimer on the bottle — if every American did only consume that one or two drinks per day, alcohol sales would be cut by something like 70% to 80%. That means we are purchasing much more alcohol than we need for everyone to have that one or two drinks per day."

She also noted that during the pandemic, women's alcohol intake increased by a staggering 41%.10 Clearly, our cultural norms around drinking are leading to widespread overconsumption, even among those who don't consider themselves to have a "drinking problem." Fortunately, Scheller sees a cultural shift beginning to take place:11

"We're at a pretty pivotal moment societally with alcohol. Over the last couple of years post-pandemic, we're seeing that there was a huge surge in alcohol intake during the pandemic ... But post-pandemic, we're seeing this huge trend toward sober curiosity, people who are looking to cut back and to limit their intake."

She cited that about 41% of Americans are currently looking to quit drinking or cut back. This growing "sober curious" movement recognizes that you don't need to hit rock bottom or label yourself an alcoholic to decide that drinking less (or not at all) could improve your life.

Scheller's Personal Journey to Sobriety
Scheller shared her own powerful story of transitioning to an alcohol-free lifestyle, which may serve as motivation for others looking to become sober:12

"I didn't have a rock bottom transition like you might see in a movie. I didn't get a DUI. I didn't lose a job. I didn't have anything blow up in my life, but I was experiencing massive amounts of anxiety and mental health concerns that were really heavily being affected by my alcohol consumption."

She realized her drinking had escalated quickly during the pandemic, starting earlier each day. This scared her enough to explore full sobriety. What she discovered transformed her life:13

"I look at what has happened because of my sobriety and because of putting down alcohol, and another part of why I'm so passionate about this is because I see this with my clients as well, that the blocks that we have in our life, the challenges that we're going through, we think alcohol is helping, and it's actually hindering us in so many ways.

And when we remove alcohol, sometimes that is the one catalyst that we need in order to improve our physical health, our mental health, our relationships, our careers, our financials, all of the things that are a struggle."

Strategies for Reducing or Eliminating Alcohol
For those interested in exploring life with less (or no) alcohol, Scheller offered several helpful suggestions:14

1.Get curious and educate yourself — Read books, listen to podcasts and learn about the health impacts of alcohol.

2.Find community support — Scheller runs an online community called the Functional Sobriety Network. There are many other support groups and resources available as well.

3.Examine your social media — Unfollow accounts that glamorize drinking and follow sober influencers instead.

4.Address the root causes — Look at why you drink — stress, social pressure, habit — and find healthier alternatives.

5.Support your body nutritionally — Supplements like L-theanine, L-glutamine, NAC, B-complex vitamins and milk thistle can help with cravings and support detoxification.

6.Stabilize blood sugar — Increasing protein intake and eating regularly helps reduce alcohol cravings.

7.Be open about your choice — Scheller encourages people to simply say they're not drinking for their health if asked.

One of the most powerful shifts Scheller advocates for is changing how you think about alcohol in your life in order to reframe your relationship with drinking:15

"Previously, the only people who did quit drinking were people that identified themselves as having a problem or maybe had to quit. And so the first thing I'll say if you're listening and you're interested is you don't have to have a problem to decide that you want to explore this. You don't need to even be that regular of a drinker for you to say, 'You know what? This is something I may want to explore.'"

In other words, choosing not to drink is a positive, empowering decision for your health — not a punishment or deprivation.

The Bigger Picture: Optimizing Mitochondrial Health
I'll admit, before diving into this research, I bought into many of the common myths about alcohol. I thought having a drink or two occasionally was relatively harmless, maybe even beneficial. Now, I see things very differently.

I used to drink alcohol a few times a year. Now, since I've learned this information, I don’t drink any alcohol at all. I encourage everyone reading this to seriously reevaluate their relationship with alcohol. Look at the research yourself. Consider whether the fleeting pleasure of a drink is worth the very real damage it causes to your body.

This deeper understanding of alcohol's impact ties into my broader research on what truly drives health and longevity: mitochondrial function. In my upcoming book, "Your Guide to Cellular Health: Unlocking the Science of Longevity and Joy," I explore how optimizing your mitochondria is the key to preventing and reversing chronic disease.

Alcohol is just one of several major factors that damage mitochondria and accelerate aging. Others include excess omega-6 fats, electromagnetic field (EMF) exposure and endocrine-disrupting chemicals. By eliminating these harmful inputs and supporting your cellular health, you can dramatically improve your vitality and lifespan.

A Cultural Shift in the Making
Scheller and I both believe we're at the beginning of a major cultural shift in how we view alcohol — similar to the changing attitudes around smoking in previous decades. As more people recognize the true health impacts of drinking, choosing an alcohol-free lifestyle will likely become increasingly common and accepted.

This shift won't happen overnight, but each person who decides to cut back or quit contributes to changing the narrative. As Scheller put it:16

"We need to be more loud and bold about it. It's, again, a big reason why in my experience, I didn't feel like I wanted to be someone who lived in the shadows about this, who was anonymous about this topic, because it is time for a change. We are on the precipice, I think, of a cultural shift around it, and it's up to each of us to take that step for ourselves and for our lives."

A Call to Rethink Your Relationship with Alcohol
I'm more convinced than ever that alcohol has no place in a truly health-optimized lifestyle. The risks far outweigh any perceived benefits or momentary pleasure. I encourage you to take an honest look at your own drinking habits. Could reducing or eliminating alcohol improve your health, energy and overall quality of life? The research strongly suggests it would.

Remember, you don't need to label yourself an alcoholic or hit rock bottom to decide that drinking less is a positive choice. "Your health and wellness is a perfectly good excuse for you to say, 'Hey, I'm not drinking right now,' or, 'I'm trying to cut back because I know that it's having a negative effect on my health,'" Scheller said.17

I encourage you to explore some of the resources Scheller mentioned, including her book "How to Eat to Change How You Drink" or her Functional Sobriety Network. Educate yourself on the true impacts of alcohol and consider what life might be like with less of it — or none at all.

Your future self — with better health, clearer thinking and quite possibly a longer lifespan — will thank you for making this change. Let's work together to create a culture where choosing not to drink is seen as the smart, health-conscious decision it truly is."

- Sources and References
1, 2, 7, 8, 9, 11, 12, 13, 14, 15, 16, 17 Youtube, Dr. Mercola, Why Even ‘Moderate’ Drinking Is Harming Your Health — Interview With Dr. Brooke Scheller
3 Int. J. Mol. Sci. 2023, 24(10), 8650
4 Gut Microbes. 2024 Jan-Dec;16(1):2392874. doi: 10.1080/19490976.2024.2392874. Epub 2024 Aug 20
5 American Association for Cancer Research, Cancer Progress Report 2024, page 52
6 J Physiol. 2023 Dec;601(24):5617-5633. doi: 10.1113/JP285362. Epub 2023 Nov 22
10 JAMA Netw Open. 2020;3(9):e2022942. doi:10.1001/jamanetworkopen.2020.22942