New Superbug NDM-1

[HORIZONS]

Well, if you follow this kind of info - here is a new one to be watching. If we say goodbye to H1N1 we can say hello to NDM-1.

Worldwide Superbug Threat Frightening
http://www.foodconsumer.org/newsite/Non-food/Disease/6666.html

Researchers at Cardiff University, the Health Protection Agency (HPA) and International colleagues reported finding a new gene, New Delhi metallo-beta-lactamase 1 (NDM-1), which alters bacteria, making them resistant to virtually all known antibiotics.

Found largely in E. coli bacteria, the most common cause of urinary tract infections, and on DNA structures, the gene can be easily reproduced and passed onto other types of bacteria.

In an article published this week in the journal Lancet Infectious Diseases, researchers note that the potential of NDM-1 spreading worldwide is "clear and frightening."

Count...


Oops - should read NDM-1 (can someone fix the title?)

[conk]

Created in a lab somewhere? Here come the vaccine scares. "Get your shot today"!!!

[morguana]

Will fix title for you shortly

*groans* it was just a matter of time for a super bug of this type to come into being
Thanks horizons, I will ask my sis and mum about this, to see what they have heard though the medical
grape vine. I would love to see more traditional mess being used for everyday illness's, it's hardly suprising
that bacteria is fighting back and becoming antibiotic immune.
M

[bashi]

This is not a fast exploding pandemic, but a slowly growing multi-resistance.
Here an article from June 2009:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786356/

[Bomack]

Actually it's not very surprising, to me anyway. The H1N1 Pandemic turned out to be pretty much of a dud, so they will continue experimenting. But I was a little surprised that they announced it so soon. Just yesterday it was reported in the mainstream media that the W.H.O. has "DECIDED" that the H1N1 Pandemic is over:


GENEVA — The World Health Organization declared the swine flu pandemic officially over Tuesday, months after many national authorities started canceling vaccine orders and shutting down hot lines as the disease ebbed from the headlines.http://www.foxnews.com/story/0,2933,598983,00.html

And using their fear-mongering tactics, they're already "prepping" the masses for the next.

Here are two more mainstream articles on this new superbug:

Reuters: http://www.foxnews.com/story/0,2933,599142,00.html

Researchers said on Wednesday they had found a new gene called New Delhi metallo-beta-lactamase, or NDM-1, in patients in South Asia and in Britain.

NDM-1 makes bacteria highly resistant to almost all antibiotics, including the most powerful class called carbapenems, and experts say there are no new drugs on the horizon to tackle it.

AP: http://apnews.myway.com//article/20100811/D9HHD2N80.html

People traveling to India for medical procedures have brought back to Britain a new gene that allows any bacteria to become a superbug, and scientists are warning this type of drug resistance could soon appear worldwide.

It's almost as if they're initially testing the publics response to the fear factor to determine whether or not it will be fruitful for them to proceed. Among other agendas, IT'S ALL ABOUT THE MONEY!

Thanks HORIZONS!

[HORIZONS]

And using their fear-mongering tactics, they're already "prepping" the masses for the next...
It's almost as if they're initially testing the publics response to the fear factor to determine whether or not it will be fruitful for them to proceed. Among other agendas, IT'S ALL ABOUT THE MONEY!


At this stage of "the game" I would have to agree with your observation.

[Bomack]

This is not a fast exploding pandemic, but a slowly growing multi-resistance.
Here an article from June 2009:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786356/



Hey bashi, Good find!

In your article, FROM A YEAR AGO, it was reported as a new gene and yet in TODAYS articles it is reported as a new gene.

After reading your article I think it may be a good idea to save it for possible future reference (in case it should disappear)!

Bob

[Kristoffer]

The virus is based in india so far, one dead of it in brussels, he was infected by it during a hospitalstay in pacistan.

Not really time to vomit by fear just yet, we all know how the "pig flu" went, just another reason to get their poisions inside your body...

Play on the reptilebrain of ours "if you dont do this you die" ..... "WHERES MA FLU SHOT!!!!"

[PINEAL-PILOT-IN MERKABAH]

say goodbye to h1n1 say hello to ndm-1. say hello to mms say goodbye to all pathogens,viruses and parasites. just make sure you have enough lemon and or lime to mix it with.

[Ross]

One big problem In India is that you can buy Antibiotics over any counter without prescription, this leads to many not being well informed and not finishing the course. In turn this allows the bacteria to become more resistent.

[Bomack]

say goodbye to h1n1 say hello to ndm-1. say hello to mms say goodbye to all pathogens,viruses and parasites. just make sure you have enough lemon and or lime to mix it with.

Personal Facts/Experience:

For years in the A.F. I was FORCED to take a flu shot (among other things). Every year I caught the flu and one year I was deathly sick from it (the shot?). Since I left (1985) I have REFUSED to take a flu shot, and I have NEVER had the flu.

My mom passed-on with pneumonia. Every year since, around the anniversary of her passing, I caught pneumonia and one year my fever was so high (almost 106F. Yes you read that right) i went into coma for two days. The doctors thought for sure that I would suffer brain damage. I did not. I started using MMS two years ago and I have now gone two years without so-much as the sniffles.

Is it all just in my head? Is it my mind controlling my body (mind over matter)? I don't know. Possibly. But what I do know is it (MMS) works for me. These are MY facts and I'm sticking to it!

Bob

[Bomack]

India rejects superbug links

Right on the heels of the Great Swine Flu Pandemic, the first announcements to the world of this "New Superbug" are reminiscent of the beginnings of the H1N1 outbreak. But I don't recall Mexico ever denouncing the reports that the first case of Swine Flu originated there.

If they continue on with making this the next pandemic I suspect that this article will soon disappear into the mists. I've seen CNN do this many times before so read it while you have a chance!


New Delhi, India (CNN) -- India has rejected findings of British scientists about a new form of drug-resistant "superbug" infecting patients who have traveled to the South Asian nation for treatment.
The Indian health ministry insisted in a written statement Thursday that such organisms were present universally.
"[T]his is a phenomenon which occurs in nature -- in the environment, may be intestines of humans and animals universally. There might be billions of such happenings at any moment," the ministry said.
Health authorities in the country, seen as a cost-effective destination for foreign medical tourists, claimed similar plasmids have been reported from the United States, Israel and Greece as well. [...]"While such organisms may be circulating more commonly in the world due to international travel but to link this with the safety of surgery hospitals in India and citing isolated examples to show that due to presence of such organism in Indian environment, India is not a safe place to visit is wrong," the ministry said.
It also objected to the naming of the superbug as New Delhi metallo-lactamase-1 and dismissed claims Indian hospitals were not safe for treatment.

http://www.cnn.com/2010/HEALTH/08/13/india.superbug.reaction/index.html

[Bomack]

Just found this posted (today's date) on Jane Burgermeister's blog (http://birdflu666.wordpress.com/):


Superbug more hype than substance, says Indian scientist: Lancet study funded by pharma
August 16, 2010
August 13, 2010 6:01 PM

Controversy over NDM-1 ‘Superbug’ Ignites Uproar in India

From CBS news:

http://www.cbsnews.com/8301-501465_162-20013644-501465.html

A study in a British medical journal reporting the existence of a drug-resistant “superbug” has ignited a controversy within Indian medical circles.

The Lancet Infectious Diseases reported that antibiotics have proved so far ineffective against a bacterial gene, which was found in patients traveling to South Asia for medical treatment. NDM-1 has been linked to the overuse of antibiotics. Lancet found that 37 Britons receiving medical treatment in South Asia carried NDM-1 back with them to the United Kingdom.

“The potential of NDM-1 to be a worldwide public health problem is great, and co-ordinated international surveillance is needed,” Lancet wrote on its website.

The Indian health establishment has since downplayed the report. Karthikeyan Kumarasamy, lead author of a March report in the Journal of the Association of Physicians in India outlining the risks posed by NDM-1, now says the warnings have been overblown.

“It’s all hype and not as bad as it sounds,” Kumarasamy was quoted by India’s Hindustan Times. “The threat of the NDM-1 is not that big as, say, H1NI (swine flu),the popular press has since deemed it.”

“The conclusion that the bacteria was transmitted from India is hypothetical. Unless we analyze samples from across the globe to trace its origin, we can only speculate,” he continued.

NDM-1, an acronym for New Delhi metallo-lactamase-1, was identified last year after an Indian hospital admitted a patient from Sweden. Meanwhile, AFP is reporting the first NDM-1-related death, an unidentified Belgian man who was treated in Pakistan following an automobile accident.

The controversy over the report of a so-called superbug has also left the Indian government particularly displeased with some officials pointing a finger of blame at foreign pharmaceutical firms for fanning the flames. Speaking with the Bombay News.net, Health Minister Ghulam Nabi Azad said the Lancet study had been underwritten by foreign drug makers.

“It (superbug) is universal and is found in the intestine of humans and animals. It is wrong to say that it is found only in India and Pakistan. They say it was found in patients who visit India and Pakistan. The study nowhere mentions if the bacteria were found even before those persons visited India.” In a similar vein, opposition leader S.S. Ahluwalia was quoted in the The Hindustan Times quoted saying: “It may be a sinister design of multinational companies around the world,” he said, adding that with globalization, it was not just populations that were migrating, but also virus [sic] and bacteria.”

[MariaDine]

- A new superbug from India could spread around the world -- in part because of medical tourism -- and scientists say there are almost no drugs to treat it.

Researchers said on Wednesday they had found a new gene called New Delhi metallo-beta-lactamase, or NDM-1, in patients in South Asia and in Britain.

U.S. health officials said on Wednesday there had been three cases so far in the United States -- all from patients who received recent medical care in India, a country where people often travel in search of affordable healthcare.

Read the news here


http://www.reuters.com/article/idUSTRE67A0YU20100811

[Shairia]

Here we go again. This must be the 2nd wave of an engineered pandemic. Line up for your vaccines because we all know they must have one in production.

[tron]

Superbug's revenge take 2...
quiet on the set!...
and rolling.....;)
http://www.studiosanning.shawbiz.ca/legion_of_super-heroes/membership/reservists/lana_lang/insect_queen_applicant.jpg

[Curative]

http://birdflu666.wordpress.com/2010/08/16/superbug-more-hype-than-substance-says-indian-scientist-lancet-scare-mongering-study-funded-by-pharma/

'The controversy over the report of a so-called super-bug has also left the Indian government particularly displeased with some officials pointing a finger of blame at foreign pharmaceutical firms for fanning the flames. Speaking with the Bombay News.net, Health Minister Ghulam Nabi Azad said the Lancet study had been underwritten by foreign drug makers.'

[Fredkc]

Speaking with the Bombay News.net, Health Minister Ghulam Nabi Azad said the Lancet study had been underwritten by foreign drug makers.

Gee, why am I not surprised.
My current "alternate source" for diabetic meds is a company in India.
Now over 90 days into using this source, I remain surprisingly flu-free.
Neither do I have any unexplained cravings for Indian food, or conversion to Hinduism.

It does look like I have temporarily escaped the "Medical Prayer Wheel" though. (oops. that sounds terribly like a Hindu thought, huh?)
The "wheel" goes like this:
1. Never provide a cure when there is more money in "treatment".
2. Since the condition is now permanent, the wheel is now reality... lets see how many can jump on and ride.
3. Even though the condition is permanent, the doctor never writes a prescription for more than 90 days. (return business assured)
4. Since doctor availability is controlled by an insurance company (changing this to a govt. office changes nothing) The insurance co. gets a piece of me too.
5. Government decrees escaping from this wheel as "dangerous", therefore illegal. (Now the govt gets a cut, through prosecution).

And all of this over a "generic" pill whose retail value is between 10 and 20 cents.

So many rice bowls, so few shekels.... sigh
Fred

[Bomack]

China to boost surveillance of superbug that resists antibiotics
By the CNN Wire Staff
September 9, 2010 -- Updated 0455 GMT (1255 HKT)

Beijing, China (CNN) -- China's capital will step up surveillance of antibiotic-resistant bacteria in response to a superbug that first emerged in South Asia and is spreading globally, state media said.

The Beijing Municipal Health Bureau will create a network to monitor major medical institutions by year's end, the China Daily newspaper reported.

Cases of the NDM-1 superbug, as it's commonly known, have been reported in countries such as Australia, Britain, Canada, Japan, the Netherlands, Sweden and the United States. China has not detected the bacteria, but is at risk of an outbreak because of geography, global travel and the overuse of antibiotics.

The improper use of antibiotics has led to one of the world's most pressing public health problems, according to the U.S. Centers for Disease Control and Prevention. Antibiotics cure bacterial infections, not viral infections such as colds and flu.

Many bacteria have become resistant to commonly prescribed antibiotics, leading to longer illnesses, more doctor visits or longer hospital stays, and the need for more expensive and toxic treatment, the CDC says. Some resistant infections can lead to death.

The New Delhi metallo-lactamase-1 (NDM-1) gene is thought to have emerged in India or Pakistan. But India has rejected British scientists' findings that travelers picked up the bacteria when they went to India for inexpensive medical treatment, including cosmetic surgery. The Indian health ministry says such organisms are present universally.

http://edition.cnn.com/2010/WORLD/asiapcf/09/09/china.lookout.for.superbugs/index.html#fbid=ip6p5aB1jF1&wom=false

Notice the countries they have listed where NDM-1 has been reported. Interesting.

[irishspirit]

no doubt in my mind this is another one made in a lab.

However, to use India as the source is a good call by the PTB. The reason I say that is because of the way the country is. Poverty in India is widespread with the nation estimated to have a third of the world's poor: Source: http://en.wikipedia.org/wiki/Poverty_in_India Rats room freely on the streets and humans beings are exposed to some of the worst conditions on the planet.

Therefore, it will not shock people as much as say, swine flu in Asia at the wrong time of the year.

[Harley]

And the big scare begins!! Just out today:


HEALTH ALERT! UPDATE: New Drug-Resistant Superbugs Found in 3 States
Published September 14, 2010 | Associated Press

BOSTON – An infectious-disease nightmare is unfolding: Bacteria that have been made resistant to nearly all antibiotics by an alarming new gene have sickened people in three states and are popping up all over the world, health officials reported Monday.

The U.S. cases and two others in Canada all involve people who had recently received medical care in India, where the problem is widespread. A British medical journal revealed the risk last month in an article describing dozens of cases in Britain in people who had gone to India for medical procedures.

How many deaths the gene may have caused is unknown; there is no central tracking of such cases. So far, the gene has mostly been found in bacteria that cause gut or urinary infections.
Scientists have long feared this — a very adaptable gene that hitches onto many types of common germs and confers broad drug resistance, creating dangerous "superbugs."

"It's a great concern," because drug resistance has been rising and few new antibiotics are in development, said Dr. M. Lindsay Grayson, director of infectious diseases at the University of Melbourne in Australia. "It's just a matter of time" until the gene spreads more widely person-to-person, he said.

Grayson heads an American Society for Microbiology conference in Boston, which was buzzing with reports of the gene, called NDM-1 and named for New Delhi.

The U.S. cases occurred this year in people from California, Massachusetts and Illinois, said Brandi Limbago, a lab chief at the Centers for Disease Control and Prevention. Three types of bacteria were involved, and three different mechanisms let the gene become part of them.

"We want physicians to look for it," especially in patients who have traveled recently to India or Pakistan, she said.

What can people do?

Don't add to the drug resistance problem, experts say. Don't pressure your doctors for antibiotics if they say they aren't needed, use the ones you are given properly, and try to avoid infections by washing your hands.

The gene is carried by bacteria that can spread hand-to-mouth, which makes good hygiene very important.

It's also why health officials are so concerned about where the threat is coming from, said Dr. Patrice Nordmann, a microbiology professor at South-Paris Medical School. India is an overpopulated country that overuses antibiotics and has widespread diarrheal disease and many people without clean water.

"The ingredients are there" for widespread transmission, he said. "It's going to spread by plane all over the world."

The U.S. patients were not related. The California woman needed hospital care after being in a car accident in India. The Illinois man had pre-existing medical problems and a urinary catheter, and is thought to have contracted an infection with the gene while traveling in India. The case from Massachusetts involved a woman from India who had surgery and chemotherapy for cancer there and then traveled to the U.S.

Lab tests showed their germs were not killed by the types of drugs normally used to treat drug-resistant infections, including "the last-resort class of antibiotics that physicians go to," Limbago said.

She did not know how the three patients were treated, but all survived.

Doctors have tried treating some of these cases with combinations of antibiotics, hoping that will be more effective than individual ones are. Some have resorted to using polymyxins — antibiotics used in the 1950s and '60s that were unpopular because they can harm the kidneys.

The two Canadian cases were treated with a combination of antibiotics, said Dr. Johann Pitout of the University of Calgary in Alberta, Canada. One case was in Alberta, the other in British Columbia.

Both patients had medical emergencies while traveling in India. They developed urinary infections that were discovered to have the resistance gene once they returned home to Canada, Pitout said.

The CDC advises any hospitals that find such cases to put the patient in medical isolation, check the patient's close contacts for possible infection, and look for more infections in the hospital.
Any case "should raise an alarm," Limbago said.
http://www.foxnews.com/health/2010/09/14/update-new-drug-resistant-superbugs-states/

Have A Nice Day!

Harley

[HORIZONS]

Thanks for the update Harley - excuse me while I go wash my hands.

And you have a great day as well :pop2:

[Harley]

Marc Siegel M.D. is an associate professor of medicine at NYU Langone Medical Center and a Fox News Medical contributor.


OPINION

5 Things You Should Know About the New Superbug
By Marc Siegel
Published September 14, 2010 | FoxNews.com

When you think of a so-called "superbug" you probably think of what’s known as MRSA (methicillin-resistant staph aureus), a bacteria resistant to many antibiotics that has been found in hospitals for decades and more recently has even appeared in gyms. But this bacteria is generally treatable, and the hype surrounding it has been greater than the risk posed to patients.

But now a new superbug is emerging that is more worrisome. A garden variety bacteria that invades the intestine, causing diarrhea, or the bladder, causing a urinary tract infection, has now acquired a gene (NDM-1) that renders it resistant to almost all antibiotics.

This bacteria has spread in India and is now jumping to other countries (including the U.S.) when people travel to India for medical tourism.

Here are a few points to keep in mind:

1. Bacteria grow in millions of colonies, and in order to survive they seek to gain resistance to the drugs that kill them.

2. India is an overpopulated country that overuses antibiotics, which increases the chance of resistance developing in patients.

3. Drug companies are not making new antibiotics to fight these bacteria, because it isn't profitable enough for them.

4. Hospitals and clinics are helping to spread these bacteria, by not using proper hygiene and disinfection techniques.

5. Even though I am concerned about this emerging bacteria, the chances that you or anyone in your family will get it are still extremely low, even if you travel to India.

http://www.foxnews.com/opinion/2010/09/14/dr-marc-siegel-superbug-mrsa-bacteria-india-drug-resistance-antibiotics/

Have A Nice Day!

Harley

[HORIZONS]

Even more news on this - This is starting to really be played up.

http://www.boston.com/news/local/massachusetts/articles/2010/09/14/superbug_patient_treated_at_mgh/

‘Superbug’ patient treated at MGH
Arrival of the germ in US casts a spotlight on global spread of drug-resistant bacteria

By Stephen Smith
Globe Staff / September 14, 2010

A person infected with a “superbug’’ that is sparking fears around the world was treated earlier this year in a Massachusetts hospital, disease trackers said yesterday. The patient had recently traveled from India, a hot spot for the germ, which is immune to many common antibiotics.
cont...

[irishspirit]

When you think of a so-called "superbug" you probably think of what’s known as MRSA (methicillin-resistant staph aureus), a bacteria resistant to many antibiotics that has been found in hospitals for decades and more recently has even appeared in gyms. But this bacteria is generally treatable, and the hype surrounding it has been greater than the risk posed to patients.

But now a new superbug is emerging that is more worrisome. A garden variety bacteria that invades the intestine, causing diarrhea, or the bladder, causing a urinary tract infection, has now acquired a gene (NDM-1) that renders it resistant to almost all antibiotics.

This bacteria has spread in India and is now jumping to other countries (including the U.S.) when people travel to India for medical tourism.

http://www.foxnews.com/opinion/2010/09/14/dr-marc-siegel-superbug-mrsa-bacteria-india-drug-resistance-antibiotics/

Now, remembering that the Commonwealth Games are currently ongoing in India, this to me would suggest that before long, we will have this world wide. One does wonder.

[shadowstalker]

Odd my landlord goes there a couple times a year, he left left the other day to go.
I guess we will be mailing our rent checks again.

[Harley]

Hi irishspirit!

Just wanted to let you know there are THREE other threads on this subject.

MODS (in-case you want to know)

http://projectavalon.net/forum4/showthread.php?4853-FDA-mandated-recall-of-MMS&highlight=ndm-1

http://projectavalon.net/forum4/showthread.php?4715-New-Superbug-NDM-1&highlight=ndm-1

http://projectavalon.net/forum4/showthread.php?4862-Scientists-find-new-superbug-spreading-from-India-Reuters-Agency&highlight=ndm-1

Thanks!

[Beth]

Thanks Harley, merged.

[HORIZONS]

When you think of a so-called "superbug" you probably think of what’s known as MRSA (methicillin-resistant staph aureus), a bacteria resistant to many antibiotics that has been found in hospitals for decades and more recently has even appeared in gyms. But this bacteria is generally treatable, and the hype surrounding it has been greater than the risk posed to patients.

But now a new superbug is emerging that is more worrisome. A garden variety bacteria that invades the intestine, causing diarrhea, or the bladder, causing a urinary tract infection, has now acquired a gene (NDM-1) that renders it resistant to almost all antibiotics.

This bacteria has spread in India and is now jumping to other countries (including the U.S.) when people travel to India for medical tourism.

http://www.foxnews.com/opinion/2010/09/14/dr-marc-siegel-superbug-mrsa-bacteria-india-drug-resistance-antibiotics/

Now, remembering that the Commonwealth Games are currently ongoing in India, this to me would suggest that before long, we will have this world wide. One does wonder.

Good point! Hopefully we wont see anything come from this.

[HORIZONS]

http://www.ibtimes.com/art/services/?url=http://www.dailyfinance.com/story/eight-deadly-superbugs-lurking-in-hospitals/19647632/?icid=fbuzz|eight-deadly-superbugs-lurking-in-hospitals/19647632/


Eight Deadly Superbugs Lurking in Hospitals


Increasingly, the hospital is becoming a dangerous place to spend time. Even if you are there for surgery and all goes smoothly, a superbug could get you, with very serious, life-altering consequences -- including possibly death.

Superbugs -- bacteria strains resistant to antibiotics -- are on the rise. Today, according to Dr. Philip Tierno, Director of Clinical Microbiology and Immunology at the Langone Medical Center at New York University, there are 2.5 million infections annually worldwide which result in about 100,000 needless deaths and cost billions of dollars in additional treatments.

One particularly deadly infection is MRSA (methicillin resistant staphylococcus aureus). While hospitals generally don't publicize cases of patients acquiring such superbugs, one incident was widely covered in the media two years ago. In that case, Alonzo Smith, an 18-year old high school football player in Kissimmee, Florida, became sick after being infected by MRSA. It was not clear where he first came in contact with the infection -- in the school's locker room or in the hospital. But it tragically killed the youngster.

One year before his death, the Center for Disease Control and Prevention reported that MRSA causes 19,000 deaths every year in the U.S., which is more than HIV/AIDS causes. The study pointed out that the number was particularly ominous because 20% of those who get the bacteria die from it and increasingly, its victims are young, healthy people like Alonzo Smith.

cont...