DMSO Info

[Naza]

I searched the site & hadn't noticed a thread devoted solely to DMSO so, I thought I'd throw in some informational links for those with the time/interest. (if I missed it, my apologies)
I'm just starting to use DMSO myself, I will post about my personal findings as I go.
I took my first internal dose today. (1 dropper in a glass of water, followed by more water) Will do a full teaspoon for tomorrow's dose.
If anyone has used DMSO and has any input, please share :)
If I come across any good links to add, I'll do so.

http://books.google.com/books?id=mLAyJBF1sVoC&pg=PA218&lpg=PA218&dq=dmso+for+tinnitus&source=bl&ots=cUWjwos3wT&sig=Nkyfawf0F0KFuxwUuCFZN1Hp_rc&hl=en&sa=X&ei=8BrhU6HnE4OHyATH8IHICw&ved=0CGwQ6AEwBg#v=onepage&q=dmso%20for%20tinnitus&f=false
http://www.health-science-spirit.com/msm.html
http://www.health-matrix.net/2011/03/15/dmso-the-real-miracle-solution/
http://cassiopaea.org/forum/index.php?topic=17014.0
http://www.drdavidwilliams.com/stop-muscle-cramps/#dmso
http://www.dmso.org/articles/information/muir.htm
http://www.naturalnews.com/037485_dmso_inflammation_muscle_pain.html#
http://www.sott.net/article/228453-DMSO-The-Real-Miracle-Solution

[WhiteFeather]

Heres another Link, and great stuff DMSO. Nice Thread Naza. ;)
http://www.lef.org/magazine/mag2007/jul2007_cover_dmso_01.htm

[Tesseract]

I've used it from time to time as a solvent, but never medicinally, although I am aware of some of the claims. As most articles point out, DMSO (dimethylsulfoxide) passes through skin very easily, and if anything is pre-dissolved in the DMSO, that will more than likely pass through as well. That can be a good or bad thing, depending on what the dissolved species is. It's also worth pointing out that there are some concerns about the toxicity of this chemical, as there are with almost any organic solvent. There are some details on the wikipedia page. Personally, I think it's benign enough to experiment with carefully, and given that there is already some history there, but one should be careful and maybe dig deeper into what kind of dosages have been safely used before - including where it is applied directly to the skin.

I advise not to keep it in plastic containers, as it will destroy certain plastics pretty easily, and may leach out toxic plasticisers from others.

[DeDukshyn]

We used to sell that at work in a capsule ... I imagine long since banned by Health Canada as a supplement ...

I tried DMAE and I'll have to say, I still keep my eyes out for this ... the dreams .. so vivid, more real than real, and you remember them all ...

That said, DMSO sounds a lot like MSM; Likely being an organic form of sulphur. sulphur is likely the real hero here, but it needs a carrier -- pure sulphur is not absorbable by the human body.

[fourty-two]

Jim Humble included a feference to DMSO involving application (of his product mixed with it) to the skin.

[johnwills]

A couple more links

http://www.livestrong.com/dmso/
http://www.micheldogna.fr/le-dmso-article-6-19-237.html (French Language)

[Rainbowheart]

a lot of different articles you can find here:

http://www.naturalnews.com

just enter "dmso" in the SEARCH field

[Timreh]

My mother has had a "frozen shoulder" for around 8 or 9 years (a chronic condition where the tissue around the shoulder joint tightens or seizes up and becomes inflamed, causing pain and limiting movement), she had undergone acupuncture, physiotherapy etc etc.. all with limited or temporary relief.

Last night she showed me a bottle of DMSO (dimethyl sulfoxide) she said 2 weeks ago a friend introduced her to it and applied it once topically to the skin around her shoulder, within 2 hrs her shoulder was completely healed, where she previously had very limited range of motion and considerable discomfort she now had full range of motion and was completely pain free.. I watched her swinging her arm around effortlessly.
Absolutely definitely worked!
I am getting my hands on some.. :thumb:

[Laurel]

I bought a bottle of DMSO about a month ago. I originally tried it on a cold sore and it worked. After researching it a bit, I found an article about an athlete who tore a ligament in his ankle and healed it with DMSO. A few years ago I tore 4 ligaments in my ankle and went through physical therapy instead of surgery. It started flaring up and I tried DMSO for about a week without much help. My injury is probably too old to heal.

What I did find is that DMSO is very strong carrier and easily passes through membrane. You have to be very careful that the area is thoroughly cleaned before applying it. Anything that comes in contact with the DMSO may be absorbed. On the good side, I think this is why it works so well with MMS.

Naza, please let us know how it works for you.

[Sue (Ayt)]

I read this newer study today, and thought it would make a good addition to this thread. (It is a pdf)

DMSO inhibits growth and induces apoptosis through extrinsic pathway in human cancer cells
Hu, Tang; Villarroel, Ariana; Duff, Angela; Ruiz, Izabella; Almeida, Adrian.
Journal of Medical Discovery; Philadelphia Vol. 5, Iss. 4, (2020): 1,211. DOI:10.24262/jmd.5.4.20055

https://www.proquest.com/openview/06527232a660b6867effa2ff8f68deed/1?pq-origsite=gscholar&cbl=2050635

[Vangelo]

I have been using DMSO topically for a week now with significant reduction in pain (better than 66% easy). Within 2 hours of the first application I noticed a difference. I have significant pain in my Achilles and the side of my heel. I purchased the roll on product with 70% DMSO and 30% Aloe. I shake the container before application and I wash my feet and then rinse with bottled water to make sure there is no chlorine or fluoride residue from my tap water.

[onawah]

DMSO Could Save Millions from Brain and Spinal Injury

DMSO Could Save Millions from Brain and Spinal Injury
Analysis by A Midwestern Doctor
October 11, 2024
https://articles.mercola.com/sites/articles/archive/2024/10/11/dimethyl-sulfoxide-dmso.aspx?ui=8d3c7e22a03f5300d2e3338a0f080d2da3add85bca35e09236649153e4675f72&sd=20110604&cid_source=dnl&cid_medium=email&cid_content=art1ReadMore&cid=20241011&foDate=true&mid=DM1642580&rid=138437677

https://media.mercola.com/ImageServer/Public/2024/October/PDF/dimethyl-sulfoxide-dmso-pdf.pdf

"Story at-a-glance
DMSO is a remarkably safe chemical that protects cells from otherwise fatal stressors (e.g., freezing, burning, shockwaves, ischemia)
Since the heart, brain, and spinal cord are particularly vulnerable to injury, DMSO can produce miraculous results when those injuries happen
Despite decades of research, many serious shortcomings exist with how we treat strokes (including brain bleeds), heart attacks, and spinal cord injuries
As I will show here, had the FDA not sabotaged DMSO’s adoption, in addition to countless lives being saved, millions could have been protected from a lifetime of disability or paralysis

If I were stranded on a desert island or knew the world was ending and I could only bring a few therapies with me, one of them, without a doubt, would be DMSO. This is because:

It effectively addresses acute injuries (e.g., sprains) and chronic musculoskeletal disorders (e.g., arthritis).
It’s one of the most effective pain killers in existence.
It treats severe, often incurable illnesses and prevents long-term disability.
It’s one of the safest medically active substances available.
Yet, despite it taking the world by storm in the 1960s and thousands of studies being performed that corroborated its benefits, outside of it being a laboratory chemical or an alternative therapy some people use for joint pain, few are even aware of DMSO’s existence.

This was due to the FDA waging a multi-decade long war against DMSO (despite widespread outcry from Congress and the public).

What Is DMSO?
Dimethyl Sulfoxide (DMSO) exists throughout nature1 and has two breakdown products within the body.

https://media.mercola.com/ImageServer/public/2024/September/what-is-dmso.jpg

Most of it is oxidized to methylsulfonylmethane (MSM — a commonly used joint healing supplement), while a small amount is reduced to DMS and gives rise to DMSO’s characteristic "side effect" a distinctive garlic or clam-like odor that is excreted through the mouth and skin for a few hours that some individuals have difficulty tolerating.

Note: Individuals with insufficient oxidation (who are in a state of reductive stress) are more likely to produce DMS. In turn, when this is addressed, their "DMSO odor" often disappears.

Due to its unique chemistry, DMSO has two remarkable properties:

It acts as a near-universal solvent (e.g., it interacts with a vast range of biomolecules).2,3
It’s able to pass through biological membranes without damaging them (something to my knowledge, nothing else can do).4
Because of this, DMSO will rapidly enter the body (including the brain) regardless of its route of administration (e.g., within 5 minutes after going on the skin it can be found in the blood,5 and within an hour it can be found within the bones6), but simultaneously does not accumulate within the body.7

DMSO, in turn, has an almost endless number of uses as it can be applied in almost any manner. Almost any drug or substance can be combined with it and administered through the skin (e.g., steroids, NSAIDs, vitamin C, or hydrogen peroxide). In many cases, the effect of those drugs is enhanced, and simultaneously, their toxicity is reduced (although, in some cases, the toxicity increases).

Cellular Protection
DMSO’s ability to spread throughout the body (including into the brain) initially seems concerning — however rather than be toxic to cells, DMSO heals them and protects them from damage from many otherwise lethal stressors (e.g., heat, blood loss, radiation, sonic shockwaves).

For example, since DMSO does not expand when it freezes and greatly lowers the freezing point of cells, it was a revolutionary substance for preserving frozen cells,8 and likewise, many cases exist of DMSO saving the fingers or toes that otherwise would have required amputation.

Note: Due to the intense scrutiny DMSO received, thousands of papers have been published on its biological effects (including numerous animal safety studies and one where humans were exposed to 3 to 30 times the typical dose for 90 days9) — all of which did not report any significant side effects from DMSO.

In turn, those studies found the most common side effect (affecting 50% to 75% of users) is (reversible) irritation at the site when 70% DMSO is applied topically on the skin (which can be easily mitigated) and the most significant was an allergic reaction in approximately 1 out of every 2000 people (which can easily be screened for).

Circulatory Disorders
DMSO is remarkably effective in managing circulatory disorders, effectively protecting tissues and enhancing blood flow by removing excess fluid, improving circulation, and dissolving clots. Its benefits are particularly evident in conditions like Raynaud’s syndrome, where it eliminated symptoms in 50% of patients,10 and in diabetic circulatory issues, with studies showing over a 94% success11 rate in treating diabetic ulcers.

DMSO also works wonders for varicose veins, often providing noticeable improvements within minutes by strengthening vessel walls and enhancing capillary circulation. In a study of 67 patients with varicose ulcers,12 remarkable responses were documented, even in chronic cases. Additionally, DMSO has been shown to help many other circulatory disorders:13,14

https://media.mercola.com/ImageServer/public/2024/September/dmso-condition.jpg
https://media.mercola.com/ImageServer/public/2024/September/dmso-condition-1.jpg

Key mechanisms behind DMSO’s effectiveness include:

•Heart function — It can increase or decrease heart contractions without affecting rhythm, enhancing cardiac output and simultaneously dilates critical blood vessels.15

•Anticlotting properties — DMSO prevents blood clot formation in the body, reduces clot promoting prostaglandins, and is a powerful platelet deaggregator.16,17,18 Its ability to safely block platelet bonding, scavenge harmful radicals, and inhibit tissue factor expression makes DMSO a standout in circulatory health.19

https://media.mercola.com/ImageServer/public/2024/September/dmso-cardiac-actions.jpg

Given all of these protective and circulatory enhancing properties, DMSO is an immensely promising treatment for heart attacks and heart attack recovery,20 and this benefit has been demonstrated in numerous animal studies.21,22 Likewise, I and colleagues have had a few situations arise where DMSO was administered to someone having a heart attack and successfully treated it.

Note: We’ve also had some success treating heart attacks by rapidly restoring someone’s physiologic zeta potential.

DMSO and Strokes
Roughly 3.1% of adult Americans have experienced a stroke23 (a figure we expect to rise from the COVID-19 vaccines). Each year, this translates to about 800,000 people in the United States having a stroke, in 2022, 165,393 dying and between 20% to 40% of survivors experiencing long term disability.24

Because of the harm strokes pose to society, and the rate at which brain tissue deteriorates once its blood supply is lost, the medical system prioritizes treating strokes as soon as possible.

Strokes come in two main types: ischemic (caused by clots blocking blood flow) and hemorrhagic (due to ruptured blood vessels). The standard treatment for ischemic strokes is tPA,25 a clot-busting drug. However, administering tPA can be deadly if the stroke is hemorrhagic, so patients must first wait for a CT scan before receiving it.

Furthermore, tPA is only effective within a limited time frame (up to 3 to 4.5 hours26), and only a small percentage of patients (1.8% to 8.5%) actually receive it. Among those who do, only 13%27 see significant improvement. Additionally, tPA can cause serious bleeding complications28 (e.g., 6.4% risk29 of a symptomatic brain bleed) and can’t eliminate larger clots.

In short, strokes remain a leading cause of death and disability worldwide.30 This highlights the need for a better treatment that can safely:

Effectively treat ischemic strokes

Has no risk of worsening a hemorrhagic stroke

Could easily be taken at home, and more importantly, be quickly given on ambulances

Protected brain tissue from dying

Prevented reperfusion injuries

Healed damaged brain tissue after a stroke

DMSO has been known for over 50 years to do just that. For example, a 2002 trial with DMSO combined with fructose diphosphate (FDP — a source of cellular energy) indicated that 63% of elderly patients experienced improved neurological status when treated within 12 hours of a stroke, compared to only 20% with standard care.31

https://media.mercola.com/ImageServer/public/2024/September/dmso-fdp.jpg
https://media.mercola.com/ImageServer/public/2024/September/dmso-angiogram.jpg

One of the most important aspects of this trial was that while DMSO is the most helpful when given immediately after a stroke, the trial showed DMSO could save the neurons long after the stroke had happened.32

https://media.mercola.com/ImageServer/public/2024/September/dmso-stroke.png

Given the existing options for strokes, a trial like this should have been immediately replicated by premier institutions around the world — but instead almost no one even knows it happened.

Note: Numerous animal studies (listed here) have also demonstrated DMSO’s effectiveness in treating ischemic strokes. Sadly this revolutionary medical treatment remains a forgotten side of medicine.

After I learned how unconscionable the FDA’s prohibition against DMSO was, I made a point to begin telling people I felt were at risk of a stroke to stock DMSO at home, and since then, I’ve had instances where someone (or their caretaker) called me up, described a stroke, I gave them instructions on what to do (since they already had DMSO at home), and by the time they got to the ER, the stroke was "resolved."

Note: In my opinion, IV DMSO would have been ideal (and more effective) in those situations, but in each case, it was not feasible to implement.

Likewise, many compelling cases have been recorded33 of individuals who treated their strokes with DMSO:

"A Los Angeles school teacher suffered a major stroke just after Christmas, found unconscious at home. Immediately, she was treated with DMSO: first applied topically to her head and then given by intramuscular injection — all without ever going to the hospital, thanks to a family friend's advice.

Remarkably, she regained consciousness later that day and continued daily DMSO treatments. By the time school resumed in January, she was back teaching, fully recovered and without any mention of her ordeal. She continued her teaching career until retirement, healthy and free of disability."

In another case, a woman in a coma for three months after a stroke showed no signs of life. Daily topical DMSO treatment was started, and within a month, her brain began to respond. After four months, she returned home and began a regimen of daily DMSO in water alongside topical applications. Three years later, she was living a normal life with only a slight speech defect, claiming her memory was sharper than her husband’s.

Note: There are also many reported cases of individuals who took DMSO for musculoskeletal or pain disorders (by far the most common use of DMSO) who then experienced a permanent improvement of stroke symptoms.

Hemorrhagic Strokes and Traumatic Brain Injuries
While ischemic strokes are difficult to treat, hemorrhagic ones (and other traumatic brain injuries) are even more challenging, and after decades, there has been surprisingly little progress in neurologic intensive care, particularly in preventing long-term paralysis and disability.34

"It was, as if the hand of God had somehow touched the [experimental] animal’s forehead. ‘I don’t believe it,’ I stammered. But it was true. I felt a tingling in my spine because this reawakening of a virtually dead animal had all the markings of a medical breakthrough.

Instead, the discovery, the potential for saving lives and the continued research that should have uncovered other uses for dimethyl sulfoxide and similar agents was quietly laid to rest in the coffers of forgotten medicine."

Note: Dr. Jack de la Torre’s observations were partly based on the fact he saw numerous animals with flatlined EEGs (which typically precede brain death and then actual death) have the EEGs come back within 10 minutes of receiving DMSO.

https://media.mercola.com/ImageServer/public/2024/September/dmso-eeg.jpg

In cases of severe brain bleeds, key challenges like increased intracranial pressure (ICP) and inflammation can severely damage brain tissue. Common treatments often fail, leading to further complications (e.g., the most commonly used ICP lowering agents like mannitol can create a "rebound ICP" which is higher than it was at the start).

Remarkably, DMSO35 effectively lowers ICP36 without the rebound effect seen with other agents, while enhancing cerebral blood flow and reducing inflammation.

Research shows DMSO can significantly improve outcomes in traumatic brain injuries. In several studies, patients with elevated ICP experienced rapid decreases in pressure and improved neurological function after DMSO treatment. For instance, one study demonstrated a drop in ICP within 30 minutes for patients with closed head trauma, leading to long-term neurological improvement.37

Additionally, DMSO also addresses many other critical aspects of traumatic brain injuries and brain bleeds (which under conventional care requires many different drugs):

https://media.mercola.com/ImageServer/public/2024/September/dmso-pathologic-event.png

Animal studies further support these findings, showing DMSO's ability to reduce brain swelling and improve survival rates in models of brain injury. Its unique properties make it a standout option in neurocritical care, addressing multiple challenges associated with brain injuries.38 To put all of this into context:

"A January 11, 1981, a news report39 in the Ocala Star Banner [page 6], carried the headline: 'DOCTOR CLAIMS DMSO SAVED 11.' The story read:

SAN DIEGO (AP) — A doctor at the University of San Diego credits the controversial drug DMSO with saving the lives of 11 people who suffered severe head injuries. Dr. Perry E. Camp, a UCSD Medical School neurosurgeon, said Friday that dimethyl sulfoxide was effective for 11 of 30 people judged near death and for which other lifesaving methods have proved useless.

'To take patients like that and have even one out of 10 survive is phenomenal,' Camp said. 'The fact that we have any survivorship at all ... doesn’t sound like much, but it is extremely encouraging,' Camp said."

Sadly, however, despite the immense amount of research conducted and these results being dramatically better than what the standard of care can offer, this remains an almost completely forgotten side of medicine.

Note: Many of the same principles hold true for concussions, and the pioneers of DMSO felt it was an essential treatment for athletes after they experienced one — particularly since unhealed concussions can predispose the athlete to long-term cognitive issues (e.g., both boxers and professional football players have a threefold risk of dementia).40,41

Spinal Cord Injuries
"We used to think that the damage caused at the moment of injury in a severe head or spinal cord injury was irreversible. But now there are animal studies and a handful of clinical cases that tell us something different. There is still a little bit of time before the injured cells die.

Based on what we’ve seen in animal studies and a handful of human situations, we think that if you can treat a head injury victim within a few hours of the injury, or a spinal cord victim within one hour, there is a good chance of preventing death or the paralysis that would otherwise occur." — Dr. Jack de la Torre

As much of the same pathology that causes permanent damage in the brain also occurs in the spinal cord (the loss of blood flow and compressive post-traumatic swelling), DMSO can produce miraculous results.42 Despite decades of research, steroids remain the standard treatment, even though they’re largely ineffective and come with significant side effects.43 In fact, spinal surgeons often use steroids simply to avoid lawsuits.44

The greatest success comes when DMSO is administered intravenously within 90 minutes of injury.45 For example, dogs that were expected to be paralyzed after spinal cord trauma regained nearly normal function after DMSO treatment.

Numerous other animal studies have also shown46 DMSO prevents spinal cord injuries from causing paralysis, and in humans numerous miraculous stories exist, such as a 16-year-old quadriplegic girl gradually regained organ function and eventually walked after a year of DMSO therapy. Even older injuries see results — one man, paralyzed for 12 years, regained some feeling and movement after using a DMSO lotion.

Cognitive Impairment and Dementia
Since many neurological disorders are linked to poor blood flow to the brain, previous traumas (e.g., concussions or microstrokes), the accumulation of misfolded proteins or an autoimmune process (all things DMSO is also remarkably effective at treating), it stands to reason that many cognitive disorders would respond to DMSO.

In turn, we find that much in the same way DMSO reverses many other complications of aging (e.g., skin issue, hair loss, poor organ function) IV DMSO is one of the most effective antiaging therapies for the brain (along with ultraviolet blood irradiation or improving the physiologic zeta potential).

Likewise, IV DMSO is one of the only therapies I know of which can help challenging neurological diseases like Multiple Sclerosis, Parkinson’s and ALS. Likewise, I periodically come across anecdotes of DMSO consuming centenarians who have no cognitive impairment despite their age. Numerous animal and human studies demonstrate this. For example:

•18 patients with probable Alzheimer’s disease47 were treated with DMSO and tested regularly for nine months, with great improvements being noted after only three months of treatment, and becoming especially noticeable after six months of treatment. Areas of improvement included memory, concentration, and communication alongside a significant decrease of disorientation in time and space.

•100 patients with cerebrovascular diseases48 (e.g., a previous stroke, cerebral embolism, or a hardening of the arteries of the brain), many of whom were senile received DMSO orally and through intramuscular injections over the course of 50 days. In addition to their coronary heart disease (i.e., atherosclerosis) and high blood pressure improving in 96.12% of them, the observing neurologist noted that their cognition, mood and behavior improved.

•A study of49 104 elderly adults with a disease process causing impaired cognition found DMSO was highly favorable for both their cognitive and psychiatric function.

Note: Since many psychiatric conditions are neurological in nature, DMSO has also been shown to be remarkably effectively here (e.g., a study50 found it had a 100% success rate in treating acute schizophrenia, and an excellent effect on psychosis from manic-depression or alcoholism, chronic schizophrenia, anxiety and obsessive compulsive disorder).

Conclusion
DMSO was discovered during a time when the scientific community was open to exploring unconventional ideas, as science had not yet been handcuffed by a grant system designed to thwart unconventional ideas. In turn, thousands of studies were published on its potential, thanks to dedicated researchers with strong institutional support.

However, despite this promising research, the FDA suppressed its development, consigning years of scientific effort and countless animal sacrifices to the dustbin of history.

This is particularly tragic given the immense suffering caused by conditions that DMSO could potentially alleviate. Decades of research and billions of dollars later, conventional medicine still struggles to treat many of these disorders effectively. Dr. Pierre Kory, after reviewing this article, shared my sentiments:

"In over 15 years of running ICUs and treating brain injuries, strokes, and bleeds, it saddens and infuriates me to know an intervention like DMSO could’ve helped so many. The treatments I relied on were often limited or came with major risks."

My goal in presenting this work is to give DMSO another chance to flourish and help those in need. I sincerely thank you for your attention and allowing me to do this!

Author's note: This is an abridged version of a longer article about the remarkable utility of DMSO which goes into greater detail on the points mentioned here (e.g., stroke recovery and spinal cord paralysis or how DMSO protects tissues from a variety of stressors), others not covered (e.g., the wealth of evidence DMSO can treat immensely challenging conditions like amyloidosis and Down Syndrome), and the protocols for internal DMSO use.

That article and its additional references can be read here (along with a companion article discussing DMSO’s remarkable utility for a variety of musculoskeletal injuries and chronic pain conditions).

A Note from Dr. Mercola About the Author
A Midwestern Doctor (AMD) is a board-certified physician from the Midwest and a longtime reader of Mercola.com. I appreciate AMD's exceptional insight on a wide range of topics and am grateful to share it. I also respect AMD’s desire to remain anonymous since AMD is still on the front lines treating patients. To find more of AMD's work, be sure to check out The Forgotten Side of Medicine on Substack."

+ Sources and References
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3, 4, 5 Ann N Y Acad Sci. 1975 Jan 27:243:20-3. doi: 10.1111/j.1749-6632.1975.tb25340.x
6 Annals of NYAOS, March 1967, Volume 141, Issue 1, Pages 85-95
7 J Clin Oncol. 1998 Feb;16(2):610-5. doi: 10.1200/JCO.1998.16.2.610
8 Cryobiology. 1987 Feb;24(1):11-6. doi: 10.1016/0011-2240(87)90003-4
9 The Human Toxicology of Dimethyl Sulfoxide, August 25, 2011 (Archived)
10 DMSO, The True Story of a Remarkable Pain-Killing Drug, January 1981 (Archived)
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13 Ann N Y Acad Sci. 1975 Jan 27:243:403-7. doi: 10.1111/j.1749-6632.1975.tb25382.x
14 Annals of NYAOS, March 1967, Volume 141, Issue 1, Pages 586-598
15, 16 Ann N Y Acad Sci. 1975 Jan 27:243:110-21. doi: 10.1111/j.1749-6632.1975.tb25350.x
17, 19, 46 The Forgotten Side of Medicine, September 16, 2024
18 Prostaglandins. 1976 Apr;11(4):599-607. doi: 10.1016/0090-6980(76)90063-0
20, 35 Pharmacological Reports, 2009, 61, Pages 225-235 (Archived)
21 J Cardiovasc Pharmacol. 2010 Jan;55(1):106-9. doi: 10.1097/FJC.0b013e3181c87a65
22 Amazon, The Persecuted Drug: The Story of DMSO
23 CDC, Cerebrovascular Disease or Stroke
24 Brain Neurorehabil. 2022 Mar; 15(1): e5
25 NINDS, Tissue Plasminogen Activator for Acute Ischemic Stroke (Alteplase, Activase®)
26 Stroke, Volume 40, Number 6, doi: 10.1161/STROKEAHA.108.544171
27 Arch Neurol. 2008;65(11):1429-1433. doi: 10.1001/archneur.65.11.1429
28, 29 Neurohospitalist. 2011 Jul; 1(3): 138–147
30 Journal of the American Heart Association, Volume 11, Number 21, doi: 10.1161/JAHA.122.027044
31 Neurol Res 2002; 24: 73-80
32 Neurol Res. 2002 Jan;24(1):73-80. doi: 10.1179/016164102101199567
33 Amazon, The DMSO Handbook for Doctors
34 Ciba Found Symp. 1975:(34):3-21. doi: 10.1002/9780470720165.ch2
36 Neurosurgery. 1981 Jul;9(1):28-33. doi: 10.1227/00006123-198107000-00005
37 Eur J Clin Pharmacol. 1991;40(1):113-4. doi: 10.1007/BF00315149
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39 Google News, Ocala Star Banner, January 11, 1981
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[onawah]

DMSO Is a Miraculous Therapy for Pain and Tissue Injury

DMSO Is a Miraculous Therapy for Pain and Tissue Injury
Analysis by A Midwestern Doctor
October 25, 2024
https://articles.mercola.com/sites/articles/archive/2024/10/25/dmso-pain-tissue-injury.aspx?ui=8d3c7e22a03f5300d2e3338a0f080d2da3add85bca35e09236649153e4675f72&sd=20110604&cid_source=dnl&cid_medium=email&cid_content=art1ReadMore&cid=20241025_HL2&foDate=true&mid=DM1649019&rid=148258852

https://media.mercola.com/ImageServer/Public/2024/October/PDF/dmso-pain-tissue-injury-pdf.pdf

(Many hyperlinks in the article not embedded here)

"Story at-a-glance
The standard approach for managing pain and musculoskeletal injuries often involves NSAIDs (e.g., ibuprofen), which are linked to serious risks, including tens of thousands of deaths annually
DMSO is a highly effective, natural pain reliever that has helped individuals disabled by chronic pain (e.g., from failed spinal surgery or severe arthritis) regain their quality of life.
It also addresses conditions that other therapies struggle to alleviate like complex regional pain syndrome
DMSO is effective in promoting wound healing and healthy scar formation, making it remarkable for surgical recovery and burns
DMSO has an 80% to 90% success rate for treating a wide range of musculoskeletal conditions, including arthritis, back and neck strains, sprains, bursitis, and traumatic injuries.
Its rapid and dramatic effects have made it popular among professional athletes for quick recovery

Modern medicine often sidelines "miracle" drugs that work too well. Despite decades of evidence showing that the naturally occurring chemical Dimethyl Sulfoxide (DMSO) is a remarkably safe and versatile treatment for a range of challenging conditions — such as strokes, head trauma, spinal cord injuries, dementia, and even Down Syndrome — it has been largely overlooked.
See; https://www.midwesterndoctor.com/p/dmso-could-save-millions-from-brain

This sidelining is particularly remarkable as DMSO is also one of the most effective treatments for acute and chronic pain, musculoskeletal injuries, and chronic degenerative conditions (e.g., arthritis).

DMSO, Nature’s Healer
DMSO is a powerful, natural compound with several unique properties that make it an incredibly versatile healing agent:

Rapid absorption — When applied to the skin or ingested, DMSO quickly spreads throughout the body.

Cellular protection — It shields cells from lethal stressors like burns, frostbite, blood loss, radiation, and shockwaves, and can rescue already damaged cells on the verge of dying.

Safety profile — DMSO is extremely safe,1 and in almost all cases, its only side effects are temporary skin irritation or creating a garlic-like odor. In contrast, the standard of care (NSAIDs) kill tens of thousands of Americans each year and are the leading cause of drug induced hospital admissions.

Conduction blocking — DMSO selectively blocks pain signals from small nerve fibers (e.g., C fibers)2,3,4 which are often involved in chronic pain (e.g., DMSO is one of the most effective treatments for complex regional pain syndrome). This blocking effect is reversible and doesn't cause tolerance.

Choline esterase inhibition — By inhibiting acetylcholinesterase,5,6,7,8 DMSO boosts acetylcholine levels, enhancing parasympathetic function and reducing pain.

Anti-inflammatory action9 — DMSO is incredibly effective at rapidly reducing inflammation (e.g., it lowers inflammatory cytokines, scavenges free radicals, and drains edema that would otherwise compress tissues).

Muscle relaxation — DMSO rapidly relaxes skeletal muscles, easing pain from tension and spasms.10,11,12

DMSO and Tissue Healing
DMSO greatly improves wound healing (e.g., from burns or surgeries). For example:

•A study of 1371 chronic skin wounds that had often remained unhealed for years (e.g., infected ulcers or severe burns) found 95.04% had a rapid and complete recovery (e.g., no burn scars).13 Likewise, a systematic review found DMSO effectively treated ulcers.14

•Numerous studies show that DMSO accelerates limb regeneration in animals15 and surgical wound healing in humans.16 It also enhances the viability of skin grafts and flaps, offering benefits for plastic and reconstructive surgery.17,18,19,20,21,22

•Animal studies have shown DMSO increases the tensile strength of surgical scars23,24 (which significantly improves surgical outcomes), decreases experimentally induced intestinal adhesions25 (a common complication of abdominal surgeries) by 80%, prevents hypertrophic (excessive) scar formation.26

•Human studies show DMSO can flatten and loosen keloid scars27 and gradually eliminate subcutaneous fibrosis induced by radiation.28

•Finally, DMSO is also sometimes used to repair keloid scars. For example, in one study of ten people with keloids, applying 50% to 80% DMSO a couple of times a day induced scar flattening with the loosening of the collagen surrounding the fibrous bundles.29 Similarly, another study found DMSO eliminated (through a gradual softening and reduction of it).30

DMSO and Musculoskeletal Injuries
Many of the early adopters of DMSO went from skeptics to believers because of the rapid and dramatic improvements they saw from it healing acute injuries (e.g., as they had patients with debilitating bursitis in the shoulder recovering within minutes of receiving DMSO).

As it was far safer and more effective than any other way to treat musculoskeletal injuries, joint disorders or chronic pain, DMSO was rapidly adopted by doctors and pharmaceutical companies across the country (e.g., millions were invested to bring DMSO products to market and hundreds of thousands of Americans had life-changing benefits from it).

https://x.com/MidwesternDoc/status/1845727169273868623

Unfortunately, as DMSO’s use was skyrocketing, on November 10, 1965, the FDA decided to globally ban all research on it by falsely claiming it was incredibly dangerous. Because of this, there was an explosion and then sudden disappearance of DMSO research, which sadly continued even with Congress repeatedly trying to get the FDA to overturn their indefensible prohibition of DMSO.

Note: A detailed review of DMSO’s extensive safety data and toxicology studies can be viewed here. https://www.midwesterndoctor.com/p/the-remarkable-history-and-safety

As a result, very little knowledge now exists of DMSO’s use in human musculoskeletal injuries other than it existing in a few FDA approved products (where it typically is combined with another agent). Remarkably however, it is fully permitted in veterinary medicine (which led to a lot of Americans using DMSO that was "meant for horses") where it is frequently utilized for musculoskeletal injuries. Those forgotten studies include:

A 1964 study,31 where 22 out of 25 patients with subacromial bursitis experienced a rapid improvement within 30 minutes of DMSO, while in chronic cases 32 of 40 patients improved and in some patients, a reduction in shoulder calcium deposits was also noted (which in a later 1967 study,32 were shown on X-ray to disappear following DMSO).

https://media.mercola.com/ImageServer/public/2024/October/1965-study-img.png
https://media.mercola.com/ImageServer/public/2024/October/1967-study-table-4.png
https://media.mercola.com/ImageServer/public/2024/October/1967-table.png
https://media.mercola.com/ImageServer/public/2024/October/musculoskeletal-disorders.png
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https://media.mercola.com/ImageServer/public/2024/October/blinded-study-table.png
In that study, its author (a former president of the Aerospace Medical Association43) remarked:

"I am convinced that the topical application of DMSO in the treatment of acute musculoskeletal conditions is a striking and significant therapeutic contribution. During the period of time I conducted clinical investigation with this medication, I practically discarded physical therapy as treatment for musculoskeletal problems because the rehabilitation of my patients was so prompt with DMSO.

There was little or no necessity to prescribe narcotics and tranquilizers since pain was promptly mitigated following topical application of DMSO."

He then conducted a follow-up double-blind study44 on patients with sprains, strains, bursitis, or tendinitis which found DMSO significantly improved those conditions and reduced the time patients lost from work.

A 1994 blinded study45 gave 157 patients with acute tendinopathies (e.g., tennis elbow) 10% DMSO gel or a placebo ointment three times a day for 14 days within 3 days of symptoms starting. Pain of movement under loading and the mobility of the joints were significantly improved after, respectively, 3 and 7 days of treatment with DMSO. After 14 days on DMSO, a further improvement was observed, and 44% of the patients (and 9% of placebo) were pain-free.

Note: DMSO has also been reported to be effective for carpal tunnel syndrome46 (and other hand issues like trigger fingers). For those struggling with carpal tunnel syndrome, I discussed our approaches to the disorder here. https://www.midwesterndoctor.com/p/the-forgotten-history-of-carpal-tunnel

Finally, a 1967 analysis47 of 76 studies using topically applied (90%) DMSO for musculoskeletal conditions found 72% improved. Specifically:

https://media.mercola.com/ImageServer/public/2024/October/overall-therapeutic-result.png

Note: The review also included 102 Traumas (contusion, fracture, etc.), 29 Tenosynovitis, 27 Neuritis, 20 Muscle spasms, 20 unspecified types of arthritis, and 220 miscellaneous issues (e.g., fibrositis, epicondylitis, synovitis, calcific tendinitis).

To quote the authors:

"It is difficult to declare that a drug has efficacy on the basis of uncontrolled studies in a heterogeneous group of diseases. However, from these data and from discussions with many of our investigators, we feel that DMSO is a unique and effective agent for the treatment of many acute musculoskeletal disorders.

Beneficial results are unpredictable, but they occur frequently and are sometimes dramatic, particularly in acute conditions, which require low doses and short treatment periods. In chronic conditions, improvement occurs at a lower rate and is less dramatic."

Finally, at a symposium on DMSO,48 data on 9,521 patients were presented, which showed DMSO was effective therapy in a wide variety of acute traumatic conditions, in acute and chronic subacromial bursitis, osteoarthritis, gouty arthritis, and in some patients with rheumatoid arthritis (along with other conditions such as early Dupuytren’s contracture).

Note: A later 1981 study49 also found DMSO was superior to indomethacin in the treatment of gout.

Sports Injuries
"What I like about DMSO is that you don’t have to interrupt your training every time you get a minor pull or sprain. It doesn’t pump you up like certain pills. It’s simply a very useful thing to use for simple athletic injuries.

Some people have told me that you shouldn't use it because it might mask the pain of a serious injury, but a good athlete knows his body well. Even when I’m using DMSO, I know when I can push and when I can’t." — Al Oerter, a discus thrower and the first American to win 4 consecutive Olympic gold medals.50

One of the greatest challenges professional athletes face are sports injuries which prevent them from returning to the field, particularly since many sports injuries are a product of micro-injuries building up until a critical point is passed (e.g., from adhesions and scars in the soft tissue).

In turn, since DMSO both heals micro-injuries and rapidly treats traumatic injury (returning them to full functionality), DMSO was rapidly adopted by professional athletes once they realized what it could do for their careers (and being off the field was often devastating to their careers).

In turn, due to the voice their position afforded them, a few professional athletes (e.g., Atlanta Falcons Quarterback June Jones51 — who now is a coach52) became some of the most impactful advocates for DMSO (e.g., Jones stated in Congressional testimony53 that "veterinary" DMSO was widely used but athletes were afraid of publicly discussing it). Likewise, in 2013, a Dallas Cowboys Lineman stated:54

"You get it [from] the veterinarian and it goes right to the bloodstream. It’s an ointment that’s like anti-inflammatory. You put it on your skin and you put it on a muscle, and I guarantee you, in about 30 minutes you’d feel it. It wasn’t on the list [of banned substances] ... we used DMSO and people knew it. Everyone knew about it."

Furthermore, in his riveting testimony, Jones provided cases that left the Congressmen in disbelief, such as a teammate with a bone chip and a torn ligament (which would require months of recovery and hence end their season) taking DMSO immediately after the injury and 7 or 8 days later returning to the field (with the bone chip remaining but no longer causing issues).

Likewise, at that Congressional hearing, the former team physician for the Oakland Raiders55 testified that he’d used 70% topical DMSO on a careful and controlled basis for his players 20 to 30 times a year for 5 years. From this, he observed that DMSO was the most beneficial when given in the first 3 to 4 days of an acute injury where a muscle or joint had severe swelling, particularly of the extremities, especially the ankle, elbow, hands, or wrist.

Overall, he stated that DMSO provided good to excellent results 70% to 80% of the time (e.g., through reduced pain and swelling) and the players felt they were able to return to play 50% to 75% faster than they had from similar injuries in the past. Conversely, they did not find DMSO was helpful for chronic injuries, but this may have been due to it not being used long enough for the effects to kick in.

Note: He also emphasized that DMSO would transform the field of occupational medicine. I fully agree with his assessment, especially given just how frequently Worker’s Comp fails to help its patients.

Similarly, podiatrist Lowell Scott Weil (who was the physician for both the Chicago Bears and the United States Olympic gymnastics team) used DMSO on a regular basis (particularly injured gymnasts).

After 12 years of using it, he shared,56 he’d seen it rapidly heal injuries (e.g., he had a gymnast who suffered an ankle sprain expected to end her season, but instead quickly recovered and made the U.S. Olympic team, and a football player who tore his hamstring but was able to rapidly return to the field).

Overall, he had a 60% treatment success rate and saw the best response to DMSO for tendinitis, myositis, and post-injury situations such as muscle pulls, ankle sprains, strains, and tears of the soft tissue (and conversely the only side effects he had were skin irritation). Additionally, he also used it for arthritic patients (especially rheumatoid arthritis) with many having dramatic relief. Many other compelling anecdotes exist.

For example, this book57 discusses the experience of an Oregon State track coach and early adopter of DMSO who had many amazing stories of DMSO treating hamstring and achilles tendon injuries such as an athlete being able to return to the field at full capacity 3 days after a normally disqualifying hamstring injury and the story of a blind long distance runner who was able to run due to DMSO fixing musculoskeletal injuries and (according to the author) then played a pivotal role in opening the sport to women.

Note: A major problem in certain sports like football is repeated concussions (which are now recognized to put them at risk for cognitive impairment and dementia later in life). As discussed in the first part of this series, https://www.midwesterndoctor.com/p/dmso-could-save-millions-from-brain
...in addition to treating strokes and spinal cord injuries, DMSO is also immensely helpful for mitigating the effects of concussions.

Research also directly demonstrates DMSO’s utility in sports medicine:

•A 1965 study58 treated 47 injured athletes from a wide range of sports (e.g., tennis, diving, or wrestling) by applying 90% DMSO applied to the injured areas 3 times a day initially and then after 2 days, twice a day. The 30 acute traumas (e.g., sprains, strains, dislocations, serious cuts) were observed to rapidly resolve, sometimes "so spectacularly as to compel us to urge our patients to observe greatest caution in order to avoid further damage to a joint."

The 10 chronic conditions (e.g., tennis elbow) and 7 conditions resulting from prolonged immobilization also responded rapidly and those athletes were often able to quickly return to the field. These results and the lack of observed adverse events led the investigators to argue DMSO urgently needed to become the standard of care in sports medicine.

•A study59 of 78 patients (mostly athletes) with overstrained tendons received Dolobene gel (15% DMSO, dexpanthenol and heparin) for 2 to 3 weeks, with over 50% having a significant improvement of symptoms and those improvements including a 94% improvement in pain, a 55% improvement of swelling, 95% improvement of redness and 92% improvement of warmth.

•A study60 gave Dolobene gel to 30 athletes with soft tissue injuries of the upper and lower extremities twice daily for 4 weeks. There were 4 athletes with contusion of the shoulder, 8 with distortion and contusion of the knee joint, 8 with muscle, tendon and ligament lesions, and 10 with distortion of the ankle joint.

Following DMSO, 10 had an excellent response (improvement), 5 had an excellent to good response, 10 had a good response and 5 had a moderate response. Specifically, pain, inflammation, swelling, reabsorption of hematomas, tenderness and recovery time were assessed.

•A study61 gave Dolobene gel and ultrasound to 15 subjects who had received a blunt tissue trauma (without fracture) to the lower extremity within the last 24 hours. Compared to 15 placebos, the treatment resulted in a faster relief of pain, reduction of edema, and recovery of mobility.

•A 1966 study62 of 28 professional baseball players found that giving them DMSO after injuries caused their downtime be one third of what was observed by the treating physician in the previous year with 42 players.

Note: While not quite the same as getting tackled, I’ve also come across cases63 of individuals taking DMSO immediately after getting hit by a car while crossing the street (which caused injuries but no fractures) and immediately fully recovering.

Conclusion
Many of the benefits of DMSO are so extraordinary that they understandably invite a healthy degree of skepticism, and it is for that reason I have spent months carefully compiling the evidence behind it. Likewise, after presenting the initial case for DMSO to the readership of the Forgotten Side of Medicine, I put out a call for what those who’d tried DMSO had experienced.

In those comments, dozens of readers reported remarkable experiences of DMSO, many of which mirror those described throughout this article, but also other even more remarkable ones (e.g., for a child with Down Syndrome, a man with Parkinson’s and a woman who had severed her spinal cord).

The suppression of DMSO has always deeply bothered me, and in turn, I feel incredibly grateful to be alive at a time when the world is ready to learn of the suppressed medical truths many before me (e.g., the DMSO researchers) devoted their lives to bring to humanity.

Furthermore, I believe this is just the start, as beyond open platforms like Twitter (X) rapidly eroding the public’s trust in corrupt medical dogmas, I know through trusted confidants directly connected to RFK Jr. that the next four years offers an unprecedented opportunity to begin rectifying many of the previously insurmountable problems that have plagued our health care system and make America Healthy Again.

Author's note: This is an abridged version of a longer article that goes into greater detail on the points mentioned here, others not as extensively covered (e.g., the wealth of evidence DMSO is a life-changing pain treatment), and guidance for topical DMSO use (e.g., dosing, therapeutic precautions and where to obtain it).

That article and its additional references can be read here (along with a companion article discussing DMSO’s remarkable utility for a variety of musculoskeletal injuries and chronic pain conditions and an article about how DMSO treats a variety of "incurable" autoimmune and genetic disorders).

A Note from Dr. Mercola About the Author
A Midwestern Doctor (AMD) is a board-certified physician from the Midwest and a longtime reader of Mercola.com. I appreciate AMD's exceptional insight on a wide range of topics and am grateful to share it. I also respect AMD’s desire to remain anonymous since AMD is still on the front lines treating patients. To find more of AMD's work, be sure to check out The Forgotten Side of Medicine on Substack."

Sources and References
1 The Forgotten Side of Medicine, October 12, 2024
2, 3 Exp Neurol. 1969 Jun;24(2):272-6
4 Neurosci Lett. 1993 Feb 19;150(2):145-8
5 ACS Chem Neurosci. 2017 Dec 20;8(12):2618-2625. doi: 10.1021/acschemneuro.7b00344. Epub 2017 Oct 16
6 Brain Res. 1991 Dec 6;566(1-2):329-32. doi: 10.1016/0006-8993(91)91719-h
7 Biochem Pharmacol. 1983 Jan 1;32(1):151-8
8 Nature. 1966 Oct 22;212(5060):405
9 The Forgotten Side of Medicine, September 29, 2024
10 Proc Soc Exp Biol Med. 1966 May;122(1):103-7
11 Ann N Y Acad Sci. March 1967, Volume 141, Issue 1, Pages 310-325
12 DMSO Symposium. Vienna: Berlin, Saladruck. Vol. 21. 1966
13 Ann N Y Acad Sci. 1975 Jan 27:243:408-11
14 Wounds UK 15(15):361-370, November 2003
15 Ann N Y Acad Sci. January 1975, Volume 243, Issue 1, Pages 257-268
16 Klin Khir (1962). 1988:(1):1-3
17 DMSO.org, March 12, 1993
18, 22 Aesthet Surg J. 2005 Mar-Apr;25(2):201-9
19 Otolaryngol Head Neck Surg. 1994 Feb;110(2):228-31
20, 21 Plast Reconstr Surg. 2007 Dec;120(7):1819-1822
23 Am Surg. 1966 Jun;32(6):421-4
24 La Presse Medicale, 01 Jan 1967, 75(1):20
25 Arch Surg. 1965 Dec;91(6):920-3
26 J Plast Reconstr Aesthet Surg. 2017 Apr;70(4):509-517
27, 29 Ann N Y Acad Sci. March 1967, Volume 141, Issue 1, Pages 638-645
28, 30 Ann N Y Acad Sci. 1967 Mar 15;141(1):603-12
31 Northwest Med. 1964 Mar:63:167-8
32, 34, 35 Ann N Y Acad Sci. March 1967, Volume 141, Issue 1, Pages 506-516
33 JAMA. 1965;192(4):309-313
36 Ann N Y Acad Sci. March 1967, Volume 141, Issue 1, Pages 586-598
37 Ann N Y Acad Sci. 1967 Mar 15;141(1):572-85
38 Ann N Y Acad Sci. March 1967, Volume 141, Issue 1, Pages 532-550
39 A Midwest Doctor, September 25, 2024
40 Ann N Y Acad Sci. 1967 Mar 15;141(1):599-602
41 Ann N Y Acad Sci. 1967 Mar 15;141(1):569-71
42 Ann N Y Acad Sci. March 1967, Volume 141, Issue 1, Pages 496-505
43 Aeropsace Medical Association
44 Curr Ther Res Clin Exp. 1971 Aug;13(8):536-40
45 Fortschr Med. 1994 Apr 10;112(10):142-6
46, 63 Amazon, The DMSO Handbook for Doctors
47, 48 Ann N Y Acad Sci. March 1967, Volume 141, Issue 1, Pages 517-523
49 Terapevticheskii Arkhiv, 01 Jan 1981, 53(7):127-129
50 Amazon, DMSO: The True Story of a Remarkable Pain-Killing Drug
51, 53 UPI Archives, December 17, 1981
52 Wikipedia, June Jones
54 New York Post, February 8, 2013
55 Dr. Graham Reedy (Archived)
56 Amazon, DMSO: Nature's Healer
57 Amazon, The Persecuted Drug: The Story of DMSO
58 Gazz. Intern. Med. Chir. 70 (1965): 1605
59, 60, 61 Springer Book Archive, DMSO, 1985, Neue Erfahrungen in der Behandlung des Sehnenüberlastungssyndroms, Pages 54–57
62 DMSO Symposium. Saladruck, Berlin, 1966

[RunningDeer]

A couple more links

http://www.livestrong.com/dmso/
http://www.micheldogna.fr/le-dmso-article-6-19-237.html (French Language)

https://i.imgur.com/qQSaluZ.gif
DMSO.store (https://dmso.store/) - You’ll find cross links there, as well.
DMSO for Eyes (https://projectavalon.net/forum4/showthread.php?119909-DMSO-for-Eyes-Glaucoma-Cataracts-Strain-Vision-Retinitis-and-the-Organ-Responsible-for-Eye-Care&p=1527798&viewfull=1#post1527798): Glaucoma, Cataracts, Strain, Vision, Retinitis and the Organ Responsible for Eye Care

[Flash]

A couple more links

http://www.livestrong.com/dmso/
http://www.micheldogna.fr/le-dmso-article-6-19-237.html (French Language)

https://i.imgur.com/qQSaluZ.gif
DMSO.store (https://dmso.store/) - You’ll find cross links there, as well.
DMSO for Eyes (https://projectavalon.net/forum4/showthread.php?119909-DMSO-for-Eyes-Glaucoma-Cataracts-Strain-Vision-Retinitis-and-the-Organ-Responsible-for-Eye-Care&p=1527798&viewfull=1#post1527798): Glaucoma, Cataracts, Strain, Vision, Retinitis and the Organ Responsible for Eye Care

Asking the question what is DMSO? here from wikipedia: Le diméthylsulfoxyde noté aussi DMSO est un solvant polaire organosulfuré, aprotique, de formule C2H6OS.

Then what does it do to humans and why?

Dimethylsulfoxide (DMSO) is a chemical that dissolves many organic and inorganic substances. It's available as a prescription drug and dietary supplement. DMSO helps medicines get through the skin and can affect proteins, carbohydrates, fats, and water in the body.

Toxicity. DMSO is a non-toxic solvent with a median lethal dose higher than ethanol (DMSO: LD50, oral, rat, 14,500 mg/kg; ethanol: LD50, oral, rat, 7,060 mg/kg). DMSO can cause contaminants, toxins, and medicines to be absorbed through the skin, which may cause unexpected effects.

LOTS of potential side effects

You should also not use DMSO without talking to your doctor if you have: Diabetes. Asthma. Liver and kidney conditions.

It is an industrial solvent, with very little research on its use for human ailments, so I would just be careful in its use. For example, being diabetic, I would definitely think twice before using it.

[RunningDeer]

Asking the question what is DMSO? here from wikipedia: Le diméthylsulfoxyde noté aussi DMSO est un solvant polaire organosulfuré, aprotique, de formule C2H6OS.

Then what does it do to humans and why?

Dimethylsulfoxide (DMSO) is a chemical that dissolves many organic and inorganic substances. It's available as a prescription drug and dietary supplement. DMSO helps medicines get through the skin and can affect proteins, carbohydrates, fats, and water in the body.

Toxicity. DMSO is a non-toxic solvent with a median lethal dose higher than ethanol (DMSO: LD50, oral, rat, 14,500 mg/kg; ethanol: LD50, oral, rat, 7,060 mg/kg). DMSO can cause contaminants, toxins, and medicines to be absorbed through the skin, which may cause unexpected effects.

LOTS of potential side effects

You should also not use DMSO without talking to your doctor if you have: Diabetes. Asthma. Liver and kidney conditions.

It is an industrial solvent, with very little research on its use for human ailments, so I would just be careful in its use. For example, being diabetic, I would definitely think twice before using it.



Hi Flash https://i.imgur.com/LAk0Fum.gif

I put DMSO is in the same alternative category as: 1) MMS 2) Hydrogen Peroxide (food grade) 3) Turpentine (100% pure pine gum). They are the Grandma remedies that today’s medical and pharmaceutical complex shouts:

”Stay Away!” “Poison!” “Onions grow out of your ears.” https://i.imgur.com/g4GnQbK.gif


If I’m talking with a stranger about alternative healing methods, I share what I’ve experimented with and add check with your doctor because everyone is different. But for myself? I don’t check with doctors. I’d wager a guess that if they’ve heard of these low cost, alternative solutions, they'd regurgitate what they were either brainwashed, paid off, or programed to say.

I gave a cursory checked of diabetes in my DMSO book. Nothing is mentioned in the Table of Contents, Chapter 3: DMSO Precautions, or Index. I should add that I don’t have diabetes, so my antenna wasn’t up when I read the book a couple of years ago.

In terms of research? I’d wager another guess as to whichever way you want to see it, it’ll be there. It’s the nature of this PSYPO video game. FWIW, I stopped counting after twenty-three DMSO books for sale @ Amazon (https://www.amazon.com/s?k=dmso+books&crid=Z0OVQ0BD3TVB&sprefix=DMSO+books,aps,127&ref=nb_sb_ss_ts-doa-p_1_10). And to save time, I’ll repost a quote of what ”Mindfulness with Kiran” suggests in the video below:




“While there are tons of health benefits of taking DMSO – you MUST do your research. Read everything about DMSO that you can get your hands on. Often, the reviews on the Amazon website can provide great insights into how people have benefitted from taking DMSO (both internally and externally).”


https://i.imgur.com/EkQUDnr.gif

Repost (https://projectavalon.net/forum4/showthread.php?119909-DMSO-for-Eyes-Glaucoma-Cataracts-Strain-Vision-Retinitis-and-the-Organ-Responsible-for-Eye-Care&p=1527952&viewfull=1#post1527952):



I purchased the "99.9% pure DMSO - Pharmaceutical grade, High purity" (no garlic smell) & "2 oz Amber Glass Bottles (https://www.amazon.com/dp/B00V73OA6O?psc=1&ref=ppx_yo2ov_dt_b_product_details), with Glass Eye Droppers" for the different strengths that I make up: eye drops and other strengths for internal and external uses.

I gathered the info from the web but decided to purchase Amandha Vollmer's book. There's also a Kindle edition.


Healing with DMSO: The Complete Guide to Safe and Natural Treatments

https://i.imgur.com/TTf4GXN.jpg




Author: “Amandha Dawn Vollmer holds a degree of Doctor of Naturopathic Medicine from the Canadian College of Naturopathic Medicine in Toronto and a Bachelor of Science in Agricultural Biotechnology.” 

Some chapter info found @ HealingwithDMSO.com (https://healingwithdmso.com).


Alexander M. Saytzeff, a Russian doctor, discovered DMSO in 1866. The use commercially was in the 1950s.

Here's a partial list from Pg. 21 "DMSO’s Activities", and other graphics.


Has antimicrobial properties
Is a muscle relaxant
Increases production of white cells and macrophages, import cells for the immune system
Increases cell membrane permeability, allowing for removal of toxins
Is radioprotective, reducing the mutagenic and lethal effects of x-rays
Is an excellent heavy metal detoxifier, binding to aluminum, mercury, cadmium, arsenic, and nickel and eliminating them though urination and sweating
Is an effective pain killer, blocking nerves conducting pain signals
Is a bacteriostatic agent, meaning it inhibits the growth of bacteria
Acts as a diuretic
Reduces inflammation and swelling by affecting inflammatory chemicals
Increases delivery of oxygen to the cells
Has a calming effect on the central nervous system
Protects the cells from mechanical damage more rapidly than pharmaceutical drugs


https://i.imgur.com/mYcrcjn.jpg

Chapters
https://i.imgur.com/UPcgp3P.jpg

Amandha Volimer links:


Amandha Vollmer Interviews (https://www.youtube.com/results?search_query=amandha+d+vollmer)
Videos on Amandha Vollmer @ Yummy.Doctor (https://yummy.doctor/video/)
HealingwithDMSO.com (https://healingwithdmso.com) - book info


Amazon summary (https://www.amazon.com/dp/1646040023?psc=1&ref=ppx_yo2ov_dt_b_product_details):



Discover the benefits that DMSO can bring to your first-aid kit, from safely soothing headaches to easing arthritis pain, in this easy-to-use, fact-filled handbook.

This science-backed guide will help you understand how DMSO works, why it works, and the many ways you can harness its power to heal your aches, pains, and other ailments, all in an easy-to-read and friendly way. DMSO (dimethyl sulfoxide) is a natural substance that comes from wood, and, when applied topically, can offer a host of pain-relieving benefits. Healing with DMSO will dispel the myths and falsehoods surrounding this substance while presenting the latest research-backed facts on how you can reap DMSO’s many benefits.

From dosages to application methods, you’ll be presented with all the information needed to find the best and safest method for using DMSO at home. Discover how you can use DMSO to speed your body’s healing process from wounds, burns, and muscle injuries. This book will help you understand how you can safely and effectively use DMSO to treat everything from headaches and inflammation to osteoarthritis and rheumatoid arthritis, all without the use of prescription medication!



https://i.imgur.com/EkQUDnr.gif

DMSO Benefits My 30 Day Experiment with UNBELIEVABLE Results (10 min)



March 31, 2021
Mindfulness with Kiran

Are you wondering about DMSO health benefits? And how can you use DMSO to improve your health? Then you are in the right place.

DMSO is a natural, non-toxic organic compound that is a by-product of paper making. Many people also call DMSO a 'Miracle Solution' because it can heal many ailments. From managing Arthritis pain to stimulate hair growth to healing soft tissue injuries and burn marks & scars - the list of DMSO benefits is endless.

In this week’s video, I share my results of taking DMSO internally for 30 days. Funny story that started on this challenge but, I share that in the video. When you do something for 30 days you start to see the impact of that activity on y our mind/body/spirit rather easily.

While there are tons of health benefits of taking DMSO – you MUST do your research. Read everything about DMSO that you can get your hands on. Often, the reviews on the Amazon website can provide great insights into how people have benefitted from taking DMSO (both internally and externally).

The results of my 30-day challenge convinced me that DMSO is an absolute must-have in my first aid. It is one supplement that my mind often goes to when I need extra support with healing inflammation.

aTO3wK7JRTc


:heart:

[onawah]

I think you would probably change your mind about DMSO's safey if you read the articles here from Dr. Mercola.



A couple more links

http://www.livestrong.com/dmso/
http://www.micheldogna.fr/le-dmso-article-6-19-237.html (French Language)

https://i.imgur.com/qQSaluZ.gif
DMSO.store (https://dmso.store/) - You’ll find cross links there, as well.
DMSO for Eyes (https://projectavalon.net/forum4/showthread.php?119909-DMSO-for-Eyes-Glaucoma-Cataracts-Strain-Vision-Retinitis-and-the-Organ-Responsible-for-Eye-Care&p=1527798&viewfull=1#post1527798): Glaucoma, Cataracts, Strain, Vision, Retinitis and the Organ Responsible for Eye Care

Asking the question what is DMSO? here from wikipedia: Le diméthylsulfoxyde noté aussi DMSO est un solvant polaire organosulfuré, aprotique, de formule C2H6OS.

Then what does it do to humans and why?

Dimethylsulfoxide (DMSO) is a chemical that dissolves many organic and inorganic substances. It's available as a prescription drug and dietary supplement. DMSO helps medicines get through the skin and can affect proteins, carbohydrates, fats, and water in the body.

Toxicity. DMSO is a non-toxic solvent with a median lethal dose higher than ethanol (DMSO: LD50, oral, rat, 14,500 mg/kg; ethanol: LD50, oral, rat, 7,060 mg/kg). DMSO can cause contaminants, toxins, and medicines to be absorbed through the skin, which may cause unexpected effects.

LOTS of potential side effects

You should also not use DMSO without talking to your doctor if you have: Diabetes. Asthma. Liver and kidney conditions.

It is an industrial solvent, with very little research on its use for human ailments, so I would just be careful in its use. For example, being diabetic, I would definitely think twice before using it.

[onawah]

How DMSO Treats 'Incurable' Autoimmune and Contractile Disorders
Analysis by A Midwestern Doctor
November 01, 2024
https://articles.mercola.com/sites/articles/archive/2024/11/01/dmso-autoimmune-contractile-disorders.aspx?ui=8d3c7e22a03f5300d2e3338a0f080d2da3add85bca35e09236649153e4675f72&sd=20110604&cid_source=dnl&cid_medium=email&cid_content=art1ReadMore&cid=20241101_HL2&foDate=true&mid=DM1652502&rid=153574795

https://media.mercola.com/ImageServer/Public/2024/November/PDF/dmso-autoimmune-contractile-disorders-pdf.pdf

(Many hyperlinks in the article not embedded here, but can be found in the pdf.)
Story at-a-glance
Broad healing potential — DMSO, a safe and highly effective treatment, has brought relief to countless people struggling with chronic pain, acute injuries, strokes, and conditions medicine often fails to address
Autoimmune support — Known for its potent anti-inflammatory properties, DMSO is particularly valuable for managing autoimmune conditions like asthma, lupus, multiple sclerosis, and interstitial cystitis
Protein support — Uniquely, DMSO helps stabilize and refold misfolded proteins, offering hope for genetic disorders and diseases with protein build-up (e.g., amyloidosis, Dupuytren’s contracture, Peyronie’s disease).
It’s even shown lifesaving benefits in challenging conditions like scleroderma
In the article, we’ll dive how DMSO helps each of these conditions and the evidence behind these impressive benefits

"Dimethyl sulfoxide (DMSO) is a simple and readily available naturally occurring chemical that rapidly enters the body through the skin and has a variety of remarkable therapeutic properties. When it was discovered, its proponents realized it represented a new therapeutic principle in medicine and once adopted, would completely change how medicine was practiced.

In turn, they conducted thousands of studies demonstrating DMSO’s overwhelming safety and efficacy in hundreds of thousands of people, but unfortunately, the FDA conducted a reprehensible campaign against DMSO1 that eventually made it become a Forgotten Side of Medicine.

https://x.com/MidwesternDoc/status/1845727169273868623

Over the last month, I’ve begun presenting that evidence. For example:

I showed here how DMSO transforms the management of strokes, spinal cord injuries, mental disability and a variety of circulatory disorders (e.g., Raynaud’s, Varicose Veins and Hemorrhoids).
I showed here how DMSO treats chronic pain, arthritis, burns, wounds and traumatic injuries (e.g., sprains and sports injuries) here.
I showed here how DMSO is one of the safest medical substances in existence.
In turn, colleagues such as Pierre Kory have begun using DMSO and reporting remarkable results. Likewise, I’ve received hundreds of extraordinary stories from readers who’ve gotten their lives back thanks to DMSO (which can be read here) and match exactly what the early pioneers of DMSO saw. Today, I will focus on some of the other critical uses for DMSO.

Note: While I have my own preferred brands of DMSO, most formulations work. When purchasing DMSO, if getting the liquid form, it is important to make sure the DMSO is of high purity and stored in a glass container (the gel form also works and is easier to apply but is also more likely to be irritating and not always as potent).

When applying DMSO topically, it is important to make sure you are not allergic to it (with a small skin test), that your skin is clean (so no chemical toxins are accidentally absorbed as well) and to only use the maximum concentration one’s skin easily tolerates (which typically is 70% but can vary from 30% to 100%).

DMSO and Protein Disorders
DMSO offers a groundbreaking approach to treating complex illnesses by stabilizing misfolded proteins,2 a key issue in many genetic disorders. Unlike pricey drugs that attempt to manage these disorders with limited success, DMSO's protein-folding support can treat a broad range of conditions, including cystic fibrosis,3 amyloidosis4,5,6,7 and even challenging neurological diseases.8,9,10 DMSO’s effect here is remarkably universal.

Note: Improving the physiologic zeta potential (an approach we typically use to treat circulatory disorders) can also stabilize protein folding (while worsening it causes aggregation and misfolding). Likewise, DMSO has been shown11 to dissolve numerous enzymes without irreversibly inhibiting them, which authors felt suggested DMSO could compensate for genetically defective enzymes.12

Remarkably, DMSO has shown promise in treating prion diseases like Creutzfeldt-Jakob,13 Alzheimer’s,14 and Parkinson’s. Testimonials reveal DMSO’s power, with reports of improved movement, energy, and coordination. For example, one reader using it for Parkinson's experienced reduced stiffness, faster movement, and improved motor skills.15

While I am very open-minded to unconventional medical ideas and knew DMSO could treat a variety of otherwise incurable neurological diseases (e.g., ALS), there was one thing I always had a bit of difficulty believing.

DMSO allegedly had been shown to cure Down Syndrome, demonstrated both in three clinical trials16,17,18 and remarkable case reports19 that were presented by multiple corroborating medical witnesses in Congressional testimony, along with numerous studies showing DMSO improved the cognition and behavior of developmentally delayed children.20,21,22,23

To explain this impossible benefit, I theorized it was likely due to DMSO’s protein stabilizing benefits, as Down Syndrome is characterized by "the aberrant accumulation of unfolded/misfolded proteins resulting from over-burdened protein quality control systems."24

What I find particularly noteworthy about this is that the "untreatability" of genetic disorders (which typically result from a dysfunctional protein) has justified spending incredible amounts of money on both research and treatments for them (e.g., the industry is still in its early stages but 20.4 billion is already spent each year on gene therapies in the United States25 — which in part explains why there was such a push to bring the unsafe mRNA platform onto the market and open up a massive new drug sector).

In contrast, DMSO is virtually free and has been shown to treat many of these disorders we still do not have a good option for.

Collagen Disorders
Abnormal collagen buildup contributes to many diseases, including rheumatologic and degenerative aging conditions. DMSO, known for addressing protein buildup, also "softens" collagen, benefiting various collagen disorders. It helps by:

Regulating MMP-9 activity to support orderly healing, reducing fibrotic diseases.26
Reducing adhesions from surgery27 and eliminating radiation-induced fibrosis.28
Treating keloids29 by loosening collagen bundles30 to flatten scars.
Strengthening incisions31 and scars to prevent excessive scar formation32 post-surgery.
Note: Many other reports of DMSO benefitting collagen disorders (e.g., this symposium, which provided data on 9,521 patients with a variety of conditions such as Dupuytren's contractures33) also exist.

DMSO has shown promising effects on collagen-related disorders like Dupuytren’s and Peyronie's, both of which involve abnormal collagen buildup. Early studies, including one from 1965,34 showed that DMSO improved range of motion in scleroderma and reduced plaque in Dupuytren’s contracture.

This condition involves thickened collagen in the palm, causing finger contractures. Standard treatments like collagen-digesting injections, needle aponeurotomy, or surgery can have complications and high recurrence rates.35 Early reports noted that long-term DMSO use led to improvements, with 3 out of 3 patients responding positively in one study,36 and partial or complete remissions in others.37

However, effectiveness seems higher when DMSO is used early, at higher concentrations, and over a prolonged period.

Peyronie’s Disease
Peyronie’s causes painful scarring and curvature of the penis, and while treatments exist, they often don't fully resolve the issue. DMSO, especially when applied early, has been reported to reduce plaque size and pain. Notably, Dr. Stanley Jacob in Portland saw relief in about half of his patients.38 Research from the Cleveland Urologists found that 6 of 13 men saw enough improvement to resume normal intercourse,39 with some experiencing reduced plaques or even complete resolution.

Note: While DMSO does not have a 100% cure rate for Dupuytren's or Peyronie's, it often works and unlike the other options is devoid of side effects. Because DMSO works best when used early and can be applied discreetly at home, it offers a powerful and accessible option for those dealing with these conditions — especially Peyronie's disease.

Rheumatoid Arthritis Contractures
DMSO has also proven useful for flexion contractures from rheumatoid arthritis, where it increased joint flexibility by 20 to 30 degrees without relapse after a follow-up.40

Fibrodysplasia Ossificans Progressiva (FOP)FOP, a rare genetic disorder causing muscles and ligaments to progressively turn into bone, is usually considered terminal and incurable. Yet, patients in studies have improved from DMSO (e.g., one regained some shoulder and hand movement and saw smaller calcified lumps).41

Scleroderma
"During the eight months I have been testing DMS:

I have been able to walk and drive a car (I had been consigned to a wheelchair by doctors at the University of Michigan Medical Center)
My terrible swallowing problem due to a calcified esophagus has improved, although I still eat baby food meats
I still have nine fingers left, free so far from amputation
I'm fighting for a change in drug evaluation to give thousands of other people a future of some promise."42

Scleroderma is a devastating disease characterized by hardening and thickening of the skin, starting with blood vessels and potentially spreading to muscles, joints, and internal organs, where it often becomes fatal.43 Despite years of research, options remain limited, with poor survival rates and frequent complications like ulcers, impaired mobility, and loss of fingers or toes due to poor circulation.44

Early research found DMSO to be remarkably helpful for scleroderma, often prompting patient protests against the FDA’s refusal to approve it.45 Studies showed DMSO’s effectiveness in healing ulcers, softening hardened skin, improving circulation, and even reducing collagen buildup.

In a landmark study of 42 scleroderma patients,46 62% experienced notable improvements, with a few even achieving remission. Many patients had to continue DMSO use to maintain benefits, but the results were life-changing.

Note: This study was initially inspired by the recognition that DMSO is very effective at treating pain, and scleroderma is often quite painful.

In a later study at the Cleveland Clinic, DMSO increased joint flexibility, restored skin suppleness, and improved grip strength.47 Russian researchers also observed rapid improvements in over 90% of scleroderma patients, with many experiencing no relapses up to five years later.48

Testimonials from patients, including a passionate plea before Congress, highlighted DMSO's potential as a safe and impactful treatment — though it's still rare for modern rheumatologists to know much about it.49 Additionally, numerous rheumatologists surveyed by Congress found it effective for scleroderma.50

Other Autoimmune Conditions
In the first two parts of this series51,52 I provided extensive research demonstrating DMSO’s ability to prevent or resolve experimentally induced inflammation (or tissue necrosis) and research mapping out DMSO’s specific anti-inflammatory properties (e.g., it inhibits numerous inflammatory cytokines), and a wealth of data showing it was an effective treatment for rheumatoid arthritis.

DMSO in turn, is well recognized for its anti-inflammatory actions, and some of my colleagues have used it for this purpose for years. Likewise, many authors have discussed its use in a variety of autoimmune disorders (e.g., this author discussed how DMSO can often be quite helpful for idiopathic thrombocytopenic purpura53). In the section below, I will discuss its use in a few key autoimmune conditions.

1.Interstitial cystitis (IC)

•Overview — IC, also known as painful bladder syndrome, can drastically affect quality of life, leading to frequent and urgent urination — sometimes up to 50 times a day — often accompanied by pelvic pain, bladder inflammation, and even blood in the urine.

•DMSO treatment — Administered as RIMSO-50, DMSO has FDA approval specifically for IC. It works by alleviating pain54 and reducing inflammation55 in the bladder wall, promoting relaxation of bladder muscles56 and preventing scar tissue formation.57

•Results — Clinical reports show that many patients experience substantial relief, with response rates varying between studies but often demonstrating a significant reduction in symptoms such as pain and urgency.58,59,60,61,62

2.Lupus

•Overview — Lupus is a complex autoimmune disease that can cause widespread inflammation and damage to various body systems. Patients often struggle with chronic symptoms and find traditional treatments inadequate.

•DMSO applications — Reports suggest that DMSO may effectively alleviate symptoms in lupus patients, even those unresponsive to steroids. Notably, some cases have shown DMSO leading to remission of lupus-related interstitial cystitis,63 demonstrating its multifaceted benefits.

•Potential impact — As a potential alternative or adjunct therapy,64 DMSO offers hope for those seeking better management of their lupus symptoms.

3.Asthma

•Overview — Asthma is characterized by inflammation and narrowing of the airways, leading to difficulty breathing. Traditional treatments often rely on bronchodilators and corticosteroids.

•DMSO benefits — Research indicates that DMSO may reduce the severity of asthma symptoms, particularly when used in conjunction with other therapies. Some studies report65 that DMSO can decrease the frequency and dosage of asthma medications required, with some patients even eliminating the need for medications altogether.

•Impact — This could significantly enhance the quality of life for asthma sufferers, providing them with more control over their condition.

4.Multiple sclerosis (MS)

•Overview — MS is a chronic disease affecting the central nervous system, leading to a range of neurological symptoms that can vary greatly between individuals and often cannot be fully managed with conventional care.

•DMSO benefits — A Russian study of 34 MS patients found DMSO provided significant benefit to them.66

•DMSO case studies — Anecdotal evidence reveals that some MS patients have experienced remarkable improvements following DMSO treatment.67

Note: There was also a reported case68 of Stanley Jacob treating a patient with ALS which resulted in "some instant, overnight and slightly delayed wonders of therapy," and this user reported69 she saw it visibly improve the condition. In our own experience IV DMSO is one of the only things which can treat ALS (typically it halts the progression of the disease).

5.Uveitis

•Overview — Uveitis is an inflammation of the middle layer of the eye, which can cause pain, light sensitivity, and vision changes.

•DMSO research — Studies conducted on dogs with uveitis have shown that DMSO effectively reduces both inflammation and intraocular pressure.70

•Human application potential — This promising research suggests that DMSO could be explored as a treatment option for humans suffering from similar inflammatory eye conditions, particularly since DMSO treats many other ocular disorders.

6.Inflammatory bowel diseases (IBD)

•Overview — Conditions like gastritis, ulcerative colitis and Crohn's disease lead to chronic inflammation of the digestive tract, resulting in symptoms like abdominal pain, diarrhea, and fatigue.

•Efficacy of DMSO — Research highlights DMSO’s potential to reduce relapse rates and inflammatory markers when added to standard therapies for ulcerative colitis.71

•Clinical significance — By enhancing the effectiveness of existing treatments, DMSO may provide a pathway to better management of IBD72 and improved patient outcomes. Many of my colleagues find DMSO is exceptionally helpful for IBD.

7.Myasthenia gravis (MG)

•Overview — MG is an autoimmune disorder that affects communication between nerves and muscles, leading to weakness and fatigue.

•DMSO mechanism — Animal studies indicate that DMSO can reduce levels of acetylcholine receptor antibodies,73 which play a crucial role in the disease's pathology.

•Future directions — While human studies are lacking, this research opens the door for potential therapeutic strategies involving DMSO in managing MG.

Note: DMSO has also been shown to suppress thyroid autoantibodies74 (a common cause of hypothyroidism).

8.Sjogren's syndrome — Sjogren's syndrome (autoimmunity of the parotid gland) results in a loss of saliva and the mouth becoming very dry. Since it is a very difficult condition to treat, this table within a larger study75 caught my eye:

https://media.mercola.com/ImageServer/public/2024/October/dmso-efficacy.jpg

Conclusion
At the time these discoveries were made more than fifty years ago, they were revolutionary, many still are (e.g., conventional medicine still cannot treat many of the conditions described here and clinically, DMSO remains one of the most anti-inflammatory agents available to us).

As a result, many physicians and desperate patients from around the country fought to make DMSO be legalized, but outside of its narrow indication for interstitial cystitis, the FDA refused to relent76 — even after many congressional representatives and senators spent decades trying to force the FDA to.

Rather, it was only after the public became so disgusted with the FDA conducting police style raids against natural medicine and Congress passed the 1994 DSHEA Act77 which prohibited the FDA from regulating naturally occurring supplements that things changed (as DMSO occurs in nature).

Sadly, by the time this happened, the damage was done and very few remembered the incredible potential DMSO had to transform the entire practice of medicine — despite the fact hundreds of thousands of Americans were using DMSO in the not too distant past.

Worse still, these monopolistic tactics never stopped, and so many remarkable therapies which could have helped all of humanity have been erased by the medical industry (e.g., consider how hard the FDA fought to bury hydroxychloroquine and ivermectin during COVID-19 so the unconscionable mRNA vaccines would face no competition).

Fortunately (due to the rapid diffusion of information facilitated by social media), these tactics have provoked such a strong backlash that an extraordinary, a once-in-a-lifetime opportunity has been created, and next week we will at last have a chance to fix this dysfunctional paradigm:



Robert F. Kennedy Jr
@RobertKennedyJr
FDA’s war on public health is about to end. This includes its aggressive suppression of psychedelics, peptides, stem cells, raw milk, hyperbaric therapies, chelating compounds, ivermectin, hydroxychloroquine, vitamins, clean foods, sunshine, exercise, nutraceuticals and anything else that advances human health and can't be patented by Pharma. If you work for the FDA and are part of this corrupt system, I have two messages for you: 1. Preserve your records, and 2. Pack your bags.
4:25 PM · Oct 25, 2024


In turn, I feel incredibly blessed to live in an era where The Forgotten Sides of Medicine can at last be rediscovered and to have been given the opportunity by the natural health community to help make that happen. For decades I never imagined what we are seeing now could ever be possible.

Author's note: This is an abridged version of a longer article that goes into greater detail on the points mentioned here, examines the unusual mechanisms that allow DMSO to treat so many different inflammatory conditions, and provides guidance for personal DMSO use (e.g., dosing, therapeutic precautions and where to obtain it).

That article and its additional references can be read here (along with a companion article discussing DMSO’s life-changing utility for a variety of musculoskeletal injuries and chronic pain conditions).

A Note from Dr. Mercola About the Author
A Midwestern Doctor (AMD) is a board-certified physician from the Midwest and a longtime reader of Mercola.com. I appreciate AMD's exceptional insight on a wide range of topics and am grateful to share it. I also respect AMD’s desire to remain anonymous since AMD is still on the front lines treating patients. To find more of AMD's work, be sure to check out The Forgotten Side of Medicine on Substack.https://www.midwesterndoctor.com/

- Sources and References
1 The Forgotten Side of Medicine
2 Handb Exp Pharmacol. 2006:(172):405-16
3 American Journal of Physiology, Cell Physiology, Volume 275, Issue 2, August 1998, Pages C599-C607
4 Eur J Clin Invest. 1977 Apr;7(2):149-50
5 Amyloidosis Academic 1976
6 Virchows Arch A Pathol Anat Histol. 1979;384(1):45-52
7 Proc Soc Exp Biol Med. 1981 Nov;168(2):172-4
8, 9 Biochim Biophys Acta. 1988 Sep 2;962(1):59-65
10 Pediatrics International, Volume 29, Issue 3, June 1987, Pages 433-440
11, 12 Annals NYAS, Volume 141, Issue 1, Biological Actions of Dimethyl Sulfoxide, March 1967, Pages 291-299
13 Brain Res Mol Brain Res. 2004 Apr 7;123(1-2):37-44
14 DMSO.org, New Possibilities in the Treatment of Patients with Alzheimer's Disease
15 The Forgotten Side of Medicine, comment
16 Ann N Y Acad Sci. 1975 Jan 27:243:421-31
17 Ann N Y Acad Sci. 1975 Jan 27:243:449-59
18, 19, 20, 51 The Forgotten Side of Medicine, September 15, 2024
21 Ann N Y Acad Sci. 1975 Jan 27:243:432-48
22 Rev. Med. Valparaíso. 1969 Dec;22(4)
23 Revista Chilena de Pediatria
24 J Alzheimers Dis. 2018;62(1):347–359
25 Gene Therapy, Volume 30, Pages 761–773 (2023)
26 J Toxicol Environ Health A. 2011;74(20):1319-22
27 Arch Surg. 1965 Dec;91(6):920-3
28 Ann N Y Acad Sci. 1967 Mar 15;141(1):603-12
29 Ann N Y Acad Sci. March 1967, Pages 638-645
30 Ann N Y Acad Sci. 1983:411:364-8
31 Am Surg. 1966 Jun;32(6):421-4
32 J Plast Reconstr Aesthet Surg. 2017 Apr;70(4):509-517
33 Ann N Y Acad Sci. 1967 Mar 15;141(1):517-23
34, 36 JAMA. 1965;192(4):309-313
35 The Bone & Joint Journal, 2018;100-B(9):1138–1145
37 Annals NYAS, March 1967, Volume 141, Issue 1, Pages 506-516
38 Amazon, DMSO: The True Story of a Remarkable Pain-Killing Drug
39 Annals NYAS, March 1967, Volume 141, Issue 1, Pages 551-554
40 Ann N Y Acad Sci. 1983:411:309-15
41 The Forgotten Side of Medicine, October 20, 2024
42, 68 Amazon, The Persecuted Drug: The Story of DMSO
43 Wikipedia, Scleroderma
44 Arch Phys Med Rehabil. 1992 Sep;73(9):811-3
45 Cleveland Clinic Quarterly, Volume 32, April 1965
46 Annals NYAS, March 1967, Volume 141, Issue 1, Pages 613-629
47 Annals NYAS, Volume 411, Issue 1, June 1983, Pages 120-130
48 Kazan Medical Journal 1974 Volume 55 No. 4
49, 50, 52 The Forgotten Side of Medicine, September 29, 2024
53 Amazon, The DMSO Handbook: A New Paradigm in Healthcare
54 Urology. 1997 May;49(5A Suppl):105-7
55 J Urol. 1972 Mar;107(3):377-80
56 Br J Pharmacol. 2007 Aug;151(7):1014-24
57 Urology. 1987 Apr;29(4 Suppl):17-21
58, 59 J Urol. 1967 Dec;98(6):671-2
60 Urology. 1978 Mar;11(3):215-20.
61 Scand J Urol Nephrol. 1978;12(2):129-31
62 J Urol. 1988 Jul;140(1):36-9
63, 64 Urology, Volume 23, Number 2, February 1984, pp. 125-127
65 Rev. Med. Valparaiso, December 1969
66 Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(9):1330-3
67 Amazon, The DMSO Handbook for Doctors
69 X, Kym Car, October 5, 2024
70 Am J Vet Res. 1989 Nov;50(11):1877-82
71 J Lab Clin Med. 1992 Jun;119(6):710-7
72 DMSO.org, Role of oxygen-derived free radical scavengers in the management of recurrent attacks of ulcerative colitis, Part 1
73 Nature. 1980 Dec 25;288(5792):733-4
74 Clinical Immunology and Immunopathology Volume 25, Issue 1, October 1982, Pages 53-58
75 Annals NYAS, Volume 411, Issue 1, June 1983, Pages 309-315
76 The Forgotten Side of Medicine, October 26, 2022
77 Office of Dietary Supplements, October 25, 1994

[onawah]

Dimethyl Sulfoxide (DMSO): Benefits, Uses and Side Effects
by Dr. Joseph Mercola
November 08, 2024
https://articles.mercola.com/sites/articles/archive/2024/11/08/dimethyl-sulfoxide-dmso-benefits-side-effects.aspx?ui=8d3c7e22a03f5300d2e3338a0f080d2da3add85bca35e09236649153e4675f72&sd=20110604&cid_source=dnl&cid_medium=email&cid_content=art1ReadMore&cid=20241108_HL2&foDate=true&mid=DM1655794&rid=158368727

https://media.mercola.com/ImageServer/Public/2024/November/PDF/dimethyl-sulfoxide-dmso-benefits-side-effects-pdf.pdf

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"Story at-a-glance
DMSO is an organosulfur compound used as a topical pain reliever and anti-inflammatory agent. It activates cellular stress responses at low to moderate levels, boosting resilience against future threats
Research shows DMSO inhibits cancer cell growth and triggers apoptosis in various cancer cell lines, suggesting promise as a targeted therapy for slowing or stopping cancer progression
In a mouse model of Alzheimer's, low-dose DMSO improved visual function, likely due to its antioxidant properties. It may be useful as an early intervention in neurodegenerative diseases
DMSO is related to MSM, which has shown benefits for joint health. It also exhibits antibacterial properties, inhibiting growth of various bacterial strains at relatively low concentrations
While promising, DMSO has side effects including garlic-like odor and skin irritation. It increases absorption of other substances and may interact with certain medications, necessitating caution in its use
You may have heard of dimethyl sulfoxide (DMSO), an organosulfur compound, as a remedy for joint pain or inflammation. DMSO is produced both naturally and synthetically. It's found in trace amounts in certain foods and widely used as a solvent in scientific research and industrial processes due to its ability to dissolve organic compounds.

In medicine, DMSO is used as a topical pain reliever and anti-inflammatory agent. It’s approved by the U.S. Food and Drug Administration for the treatment of interstitial cystitis, also known as bladder pain syndrome, a chronic condition that causes bladder pain, pressure and discomfort.1

DMSO is also used as a cryoprotectant to prevent cell damage during freezing.2 This compound shows promise for benefitting many health conditions, but it has a complex relationship with your cells. Recent research on yeast cells, for instance, reveals that DMSO's effects depend heavily on concentration and exposure time, influencing whether the compound is healing or harmful.3

DMSO: A Cellular Stressor That Builds Resilience
At low and moderate levels, DMSO activates cellular stress responses that boost your resilience. However, at higher concentrations or with prolonged exposure, it impairs cell growth and may even prove toxic. Too little DMSO didn't trigger the response, while too much overwhelmed the cells' defenses.

The key lies in how DMSO interacts with cell membranes and energy production. Short-term exposure to moderate DMSO levels didn't significantly damage yeast cell membranes or reduce their metabolic activity.4 But it did trigger stress response genes, priming cells to better handle future threats, explaining some of DMSO's protective effects.

The study found that DMSO activated yeast cells' environmental stress response (ESR) program at certain concentrations. This cellular alarm system, triggered by various mild stresses, prepares cells to better handle future, potentially more severe challenges.

It's a bit like how exercise stresses your body in the short term but ultimately makes you stronger. This stress response activation helps explain why DMSO is helpful in cryopreservation or as a protective agent against radiation damage.

At higher doses though, DMSO began to interfere with cell division and survival. Your cells' preferred energy source plays a surprisingly important role in how well they tolerate DMSO. The study found that yeast cells using primarily aerobic respiration, which relies heavily on oxygen, were most sensitive to DMSO's toxic effects. In contrast, cells using fermentation or a mix of fermentation and respiration fared better.

This difference likely stems from how DMSO interacts with mitochondria, your cell's power plants. Cells with highly active mitochondria are more vulnerable to factors that disrupt their delicate balance, including DMSO at higher doses. The compound may destabilize mitochondrial membranes, leading to increased production of harmful reactive oxygen species (ROS).

The researchers found that lowering oxygen levels in the yeast's environment increased their DMSO tolerance across the board. This suggests that DMSO's effects are closely tied to oxygen-dependent processes in your cells.

An Ally in the Fight Against Cancer
Studies reveal DMSO has another unexpected benefit: fighting cancer. Researchers investigated DMSO's impact on both leukemia cells (representing blood cancers) and epithelial cancer cells (representing solid tumors).5 They found that DMSO significantly inhibited cell growth in all tested cancer cell lines, including MV4-11 and TF-1a leukemia cells, as well as Hep-G2 liver cancer cells and MCF7 breast cancer cells.

This inhibition was both dose and time-dependent, with noticeable effects starting at concentrations as low as 2% DMSO. At 10% DMSO, growth inhibition reached up to 69% in some cell lines after 72 hours of exposure. This suggests DMSO could be used as a targeted therapy to slow down or stop cancer growth.

The study didn't just stop at observing growth inhibition — it explored how DMSO affects cancer cells. Using a trypan blue assay, which distinguishes between live and dead cells, the researchers found that 5% DMSO increased cell death rates from about 2% to 3% to 15% to 19% in leukemia cells after 48 hours. This indicates that DMSO isn't just slowing cancer cell division; it's actively killing these harmful cells.6

Under the microscope, DMSO-treated cancer cells showed significant changes in morphology. The cells shrank, their density decreased and, most importantly, their nuclei began to fragment. These nuclear fragments, visible as multiple dots within nondividing cells, are a hallmark of apoptosis, or programmed cell death.

The higher the DMSO concentration, the more pronounced these effects became. Even the adherent epithelial cancer cells, which normally form a smooth monolayer in culture, began to detach and cluster when exposed to DMSO. These observations suggest that DMSO could be triggering the cancer cells' built-in self-destruct mechanisms.

DMSO Activates Cancer Cells' Self-Destruct Sequence
Digging deeper into the molecular mechanisms, the researchers uncovered how DMSO sets off a cascade of events leading to cancer cell death. They found that DMSO significantly decreased levels of CDK2 and cyclin A — crucial proteins that regulate cell division. The CDK2-cyclin A complex, which plays a key role in driving cells from one phase of the cell cycle to the next, was particularly affected.7

By disrupting these regulators, DMSO effectively puts the brakes on cancer cell proliferation. But perhaps most tellingly, DMSO triggered DNA fragmentation in the treated cancer cells. This is considered a definitive sign of apoptosis, as it represents the cell systematically destroying its own genetic material. The researchers confirmed this by detecting increased levels of activated caspase 3, an enzyme central to the execution of apoptosis.

Interestingly, they didn't see activation of caspase 9, suggesting that DMSO triggers apoptosis through the extrinsic pathway rather than the intrinsic mitochondrial pathway. This specific mechanism could be crucial in developing targeted cancer therapies that don't harm healthy cells.

The study suggests that even at relatively low concentrations, DMSO has profound effects on cancer cell health and survival. Moreover, because DMSO is already widely used and well-tolerated in many medical contexts, it could potentially be fast-tracked for cancer treatment studies.

DMSO Improves Visual Function in Alzheimer's Model
Early animal studies raised some concerns about DMSO causing eye problems, particularly affecting the lens. These findings were not found to translate to humans,8 however, and recent research offers a more reassuring perspective for those considering DMSO as part of their health regimen.

Research using a mouse model of Alzheimer's revealed that DMSO, even at very low concentrations, significantly improves visual function.9 The study focused on 5xFAD mice, which are genetically engineered to develop Alzheimer's-like symptoms. These mice typically experience a decline in contrast sensitivity, an important aspect of vision that's also affected in human Alzheimer's patients.

Remarkably, when treated with just .01% DMSO in their drinking water, the mice showed a marked improvement in their contrast sensitivity. This improvement was comparable to the effects seen with R-carvedilol, a drug specifically being investigated for Alzheimer's treatment.

The fact that such a low dose of DMSO could produce these benefits is particularly intriguing, as it suggests DMSO's therapeutic effects may have been underestimated in previous research where it was used merely as a vehicle for other drugs.

Early Intervention Potential with DMSO
The study's findings point to DMSO's antioxidant properties as a mechanism for its beneficial effects. DMSO is well-known as a powerful scavenger of hydroxyl free radicals, which contribute to oxidative stress, a factor in the development and progression of Alzheimer's disease. The researchers observed that DMSO treatment corrected abnormalities in the retina that are associated with oxidative stress.

Specifically, they found that DMSO normalized the thickness of a particular layer in the retina (the ELM-RPE layer) that becomes contracted in the presence of oxidative stress. This correction suggests that DMSO is actively combating oxidative damage in the retinal tissue. Given that your retina is essentially an extension of your brain, these findings imply that DMSO could be providing similar protective effects throughout the central nervous system.

This is particularly exciting because oxidative stress is believed to be one of the earliest events in the development of Alzheimer's, occurring even before the appearance of characteristic amyloid plaques and tau tangles.

Given these findings, there’s potential for DMSO as an early intervention in Alzheimer's disease. The study focused on relatively young mice (4 months old) that were just beginning to show signs of visual impairment.10 The fact that DMSO was able to improve function at this early stage suggests it could be particularly valuable as a preventative measure or early treatment.

Early intervention is crucial in Alzheimer's disease, as by the time cognitive symptoms become apparent, significant brain damage has often already occurred. If DMSO can help protect against oxidative stress and maintain neuronal health from the earliest stages of the disease process, it could slow or even prevent the progression to full-blown Alzheimer's.

Moreover, the safety profile of DMSO at low doses is well-established, making it an attractive option for long-term use in at-risk individuals.

Beyond the Brain: DMSO's Wider Implications
While this study focused on visual function and retinal health, its implications reach far beyond Alzheimer's disease. The protective effects of DMSO observed in the retina extend to other tissues and organs throughout your body. Oxidative stress is implicated in a wide range of age-related conditions, from cardiovascular disease to arthritis.

For instance, DMSO is closely related to another compound that could benefit your joint health: methylsulfonylmethane (MSM). DMSO is a precursor to MSM, and both compounds share similar sulfur-based structures. Like DMSO, MSM has been shown to have significant anti-inflammatory effects, especially for joint pain. A randomized, double-blind, placebo-controlled trial in Japan explored the effects of MSM on mild knee joint pain in healthy individuals.11

Participants who took 2 grams of MSM daily for 12 weeks experienced significant improvements in their knee health compared to those taking a placebo. The study used a comprehensive measure of knee health (the Japanese Knee Osteoarthritis Measure) and found that MSM not only improved knee-specific symptoms but also enhanced overall health conditions.

This research suggests the sulfur-containing compounds in both DMSO and MSM may offer a range of health benefits, from neuroprotection to joint pain relief.

Given that DMSO can be converted to MSM in your body, using DMSO might provide some of the joint health benefits associated with MSM, in addition to its neuroprotective effects and anti-inflammatory and pain-relieving properties. These actions make DMSO an intriguing compound for overall health maintenance as you age.

DMSO's ability to inhibit and kill a range of bacteria — even at low concentrations — has also been known for decades. Researchers tested DMSO against several bacterial strains, including Staphylococcus aureus, β-hemolytic streptococci, Corynebacterium acnes, Escherichia coli and Proteus species.12

They found that a 20% concentration of DMSO was enough to inhibit the growth of all these bacteria. So, even at relatively low concentrations, DMSO can effectively stop bacterial reproduction.

DMSO Risks, Dosing Suggestions and Other Considerations
While DMSO shows promising benefits, it's important to approach its use with caution and awareness. As with any supplement or treatment, DMSO has side effects and contraindications that you need to be aware of. The most common side effect is a garlic-like taste or breath odor, which occurs because DMSO breaks down into dimethyl sulfide in your body. Some people may also experience skin irritation when DMSO is applied topically.

DMSO also increases the absorption of other substances through your skin, amplifying the effects of medications. This means you need to be careful about what comes into contact with your skin when using DMSO topically. It's also important to note that DMSO interacts with certain medications, including blood thinners and steroids.

Additionally, high concentrations may cause liver damage if used improperly. Pregnant women and those with liver disease should use caution when considering DMSO. As always, I recommend consulting with a holistic health care practitioner to determine if DMSO is right for you.

Proper product selection and dosing are key to getting the best results. A Midwestern Doctor recommends looking for DMSO that has at least 99.9% purity and, if liquid, is stored in glass. For topical dosing, start with 70% and dilute it 50/50 with water. Gradually work your way up to the full-strength product as long as no skin irritation occurs. You can also progress to a 100% DMSO product if you have thick scars or are using it for specific health conditions.

For oral dosage, a typical starting dose is 0.5 to 1 teaspoon (of 70% or 100%). You may gradually increase the dose as long as you are tolerating it well. The maximum safe dosage is up for debate, but generally 3 teaspoons is considered the upper limit. Keep in mind that since DMSO has an unpleasant taste, you’ll likely want to mix it with milk or juice when consuming it orally. Be sure to mix it well so the DMSO doesn’t settle at the bottom.

Remember, while DMSO shows promise, it's not a miracle cure. It should be considered as part of a holistic approach to health, including a nutrient-dense diet, regular exercise, stress management and other lifestyle factors that support your overall well-being. Used responsibly and under proper guidance, DMSO could be a valuable tool in your health arsenal, particularly for its antioxidant, neuroprotective, anticancer and anti-inflammatory properties."

Sources and References
1 Mayo Clinic, Dimethyl sulfoxide
2 National Library of Medicine, PubChem, Dimethyl Sulfoxide
3, 4 Scientific Reports volume 14, Article number: 21974 (2024)
5, 6, 7 Journal of Medical Discovery 2020; 5(4)
8 Arch Ophthalmol. 1968;79(4):423-427. doi: 10.1001/archopht.1968.03850040425011
9, 10 Acta Neuropathol Commun. 2024 May 31;12:85
11 Nutrients. 2023 Jun 30;15(13):2995. doi: 10.3390/nu15132995
12 JAMA. 1965;193(11):923-928. doi: 10.1001/jama.1965.03090110061015

[Frankie Pancakes]

I will look at the variety of remarkable benefits that have been observed for DMSO for conditions within the head. These results, I believe are a product of DMSO:

Being able to increase microcirculation and treat circulatory or neurological disorders6 (e.g., strokes, traumatic head injuries, spinal cord injuries, and dementia or mental disability). Being able to re-awaken cells that were dormant or on the verge of dying due to a previous stressor.7
Being able to increase parasympathetic activity.8 Having strong anti-inflammatory properties.9
Having antibacterial properties.10 Being able to easily pass through biological membranes without harming them11 and spread throughout the body (while also carrying anything mixed with it into the body).12

https://www.theburningplatform.com/2024/11/23/how-dmso-heals-the-eyes-ears-nose-mouth-and-throat/#more-354700

[onawah]

How DMSO Revolutionizes Skin Care and Dermatology
Analysis by A Midwestern Doctor
December 27, 2024
https://articles.mercola.com/sites/articles/archive/2024/12/27/dmso-skin-care-dermatology.aspx?ui=8d3c7e22a03f5300d2e3338a0f080d2da3add85bca35e09236649153e4675f72&sd=20110604&cid_source=dnl&cid_medium=email&cid_content=art1ReadMore&cid=20241227_HL2&foDate=true&mid=DM1678749&rid=193003373

https://media.mercola.com/ImageServer/Public/2024/December/PDF/dmso-skin-care-dermatology-pdf.pdf

(Hyperlinks in the article not embedded here)

"Story at-a-glance
DMSO has unique therapeutic properties that address the root causes of various illnesses, including many skin-related issues
DMSO protects the skin from damage (e.g., radiation, chemotherapy, freezing, blood loss) and promotes the healing of injuries like burns, chronic wounds, and surgical incisions
It also addresses common dermatological conditions like hair loss, psoriasis, shingles, herpes, skin cancer, lichen sclerosis, acne, eczema, sunburn, and skin infections
DMSO treats circulatory disorders such as hemorrhoids, varicose veins, venous and diabetic ulcers, and Raynaud’s
DMSO also helps with issues such as nail problems, pruritus, mastitis, insect/animal bites, and skin growths. The article reviews how DMSO can be used for each of those conditions


Dimethyl Sulfoxide (DMSO) is a remarkably safe and naturally occurring substance1 (provided you use it correctly) that rapidly improves a variety of conditions medicine struggles with — particularly chronic pain.2 For reference, those conditions included:

Strokes, paralysis, a wide range of neurological disorders (e.g., Down Syndrome and dementia) and many circulatory disorders (e.g., Raynaud’s, varicose veins, hemorrhoids), which I discussed here.

A wide range of tissue injuries such as sprains, concussions, burns, surgical incisions, spinal cord injuries (discussed here).

Chronic pain (e.g., from a bad disc, bursitis, arthritis or complex regional pain syndrome), which I discussed here.

A wide range of autoimmune, protein, and contractile disorders such as scleroderma, amyloidosis, and interstitial cystitis (discussed here).

A variety of head conditions, such as tinnitus, vision loss, dental problems, and sinusitis (discussed here).

A wide range of internal organ diseases such as pancreatitis, infertility, liver cirrhosis, and endometriosis (discussed here).

This begs an obvious question — if a substance capable of doing all of that exists, why does almost no one know about it? Simply put, like many other promising therapies, it fell victim to a pernicious campaign by the FDA which kept it away from America despite decades of scientific research, Congressional protest, and thousands of people pleading for the FDA to reconsider their actions. Consider for example this 60 Minutes program about DMSO that aired on March 23, 1980:
https://x.com/i/status/1845727169273868623

Fortunately, we have now entered an unprecedented era where the FDA’s war against natural medicine is at last coming to an end:
https://media.mercola.com/ImageServer/public/2024/December/rfk-jr-tweet-x.jpg

C4yfP_tTiMg

DMSO and the Skin
DMSO is able to treat so many different conditions because its therapeutic properties (e.g., being highly anti-inflammatory,4 improving circulation,5 stabilizing proteins6 and rescuing cells trapped in the cell danger response7) underlie many different disorders. In turn, individuals who take it for one issue will frequently observe other issues fix themselves as well — particularly since DMSO rapidly spreads throughout the body once administered.8

As a result, since opening up this topic, I’ve received over a thousand reports from readers who have had almost unbelievable results from DMSO — many of which came from surprised readers who had a condition I had not yet covered improve (e.g., better sleep and more vivid dreams9).

Note: Unexpected improvements are also commonly reported from other systemic therapies that treat the root cause of disease like ultraviolet blood irradiation (a therapy which has numerous effects that overlap with DMSO’s).

Since DMSO is often applied through the skin, the DMSO field quickly noticed DMSO helped a lot of skin conditions, to the point some doctors began using DMSO10 as their default treatment for challenging dermatologic cases when they weren’t sure what else to do (as it often worked and posed no risk to their patients).

Likewise, I’ve received a large number of reports from readers that discovered DMSO greatly helped a variety of skin condition. These include:

It causing aging skin to be rejuvenated and look much younger and healthier (e.g., it happened in a few days to a 101 year old grandmother,11 another reader reported incredibly smooth skin,12 another reported clearer skin13 and another reported14 smoother skin on her face despite not applying it there and another reported15 it improved crepey skin on the neck and sun damaged skin on the chest). Likewise, this reader reported a significant improvement of ancient stretch marks.16

A dramatic improvement of chronic hemorrhoids,17,18,19 spider veins,20 and varicose veins.21,22,23,24,25,26,27,28,29

Dozens of acute burns30 rapidly recovering and severe burns healing (e.g., a reader astonished by the complete recovery of a ten year old third-degree finger pad burn,31 a reader who had it rapidly treat blistering burns on the thighs,32 a father recovered from a severe electrical fire burn),33 and sunburns.34

Accelerating the healing of bruises35,36 (including from IV lines37 or traumatic falls.38,39) along with it dissipating capillary bleeds under the skin40,41 and reducing leg swelling.42

Accelerating the healing of an ear surgery43 a significant leg rash (that followed a traumatic impact)44 and a punctured cuticle.45

Genital herpes (including outbreaks where nothing else worked).46,47

Mastitis48 and other bacterial and fungal skin infections.49,50,51

Classic dermatologic conditions like actinic keratosis,52 hidradenitis suppurativa,53 lichen planus,54 lichen sclerosis,55 lumps,56 elbow and eyelid growths,57,58 moles,59 sebaceous cysts,60 and plantar warts,61 psoriasis,62 rosacea63 and severe chronic itching,64 skin tags,65 seborrheic keratosis.66

It being miraculous for poison ivy,67 and fire ant bites68,69 along with using it for a black widow bite,70 or pit viper bites.71

Large abscess in cat,72 oozing cysts in a Golden Retriever73 and severe vasculitis in a dog.74

Other challenging skin conditions that lacks safe or effective treatment option (e.g., "a miserable one nothing else worked on").75,76

As I will show in this article, those same effects have also been reported throughout the medical literature — yet remarkably, the dermatologic profession remains unaware of it.

Skin Microcirculation
I presently believe two of the most critical things for skin health is its microcirculation and the minute fluid movement within its interstitium77 (a newly discovered organ system that conducts interstitial fluid throughout the body I realized has many parallels to Chinese’s medicine’s twelfth organ, the Triple Burner78).

C4yfP_tTiMg

A myriad of skin conditions in turn respond to improving these circulations (e.g., by improving the skin’s zeta potential or applying DMSO). Likewise, we believe the health of this circulation determines if sunlight can be transferred into the body through the skin and function as a critical nutrient for the body or if it is unable to and prolonged sunlight exposure instead burns the skin.

Note: This transfer is also heavily influenced by the health of the mitochondrial electron transport chain (which like Dr. Mercola I believe is a key component of health). Additionally, it is often heavily influenced by what we eat (e.g., changing one’s diet can significantly improve their metabolism of sunlight and reduce their tendency to sunburn).

Protecting the Skin
Many of DMSO’s therapeutic properties come from its ability to protect tissues79 (e.g., the brain and the internal organs) from danger and death. Numerous studies in turn, corroborate DMSO’s ability to protect the skin:

DMSO can treat tissue damage from chemotherapy drugs that cause ulcers by leaking into surrounding areas (as shown by many studies,80 including one where it protected the eyelids from chemotherapy injected in their vicinity81).
It protects skin during freezing and thawing82,83,84 include a case where DMSO saved fingers from frostbite that would otherwise require amputation.85
DMSO protects skin cells from radiation damage86,87,88,89,90,91 and shields skin from gamma radiation exposure.92
DMSO reduces skin irritation caused by pulsed ruby lasers and enhances healing when combined with a low dose of a topical steroid.93
It protects surgically created skin flaps from dying due to poor blood flow94,95,96,97,98,99,100,101,102,103,104 (including in a rat model of smokers105) and shows promise in plastic surgery applications.106
Burns
The protective mechanism of DMSO which most commonly applies to the skin is its remarkable utility for burns and sunburns (e.g., I’ve received over a dozen reports of it immediately healing a cooking burn).

DMSO in turn has been shown to treat a variety of burns (e.g., superficial burns107 or partial thickness burn wounds108) without being prone to producing infections.

Studies, such as one by Russian burn specialists,109 found DMSO superior to other existing treatments. It has also been shown to prevent severe acid burns110 from worsening and helps heal alkali burns to the esophagus111 and eyes by inhibiting destructive inflammation.112

Note: In one extraordinary instance DMSO was reported to rescue a child’s finger that had been charred black after being held in a light socket.113

Venous Disorders
Presently, I believe many venous disorders arise from a combination of weakened blood vessels which is often due to inadequate nutrition and an impaired physiologic zeta potential (discussed further here) which creates congestion in the veins.

Furthermore, this becomes much more problematic if the blood vessels are weakened, a very common issue in patients with hypermobility (who tend to also be much more vulnerable to pharmaceutical injuries) due to them also having looser blood vessel walls.

Since DMSO is venotropic (enhances venous function), anti-inflammatory,114 and eliminates pain,115 a group of investigators tested116 a spray containing DMSO plus a few other medications on ulcers and over three years found:

https://media.mercola.com/ImageServer/public/2024/December/double-blind-treatment.jpg

Others also had success with this spray. In one double-blind study, it healed the veins of patients who had recovered from DVTs,117 while another team found it decreased the visible hyperpigmentation and indurations in post-thrombotic patients and improved the healing of veins that were operated on.118,119,120

Note: While there are numerous studies showing DMSO’s utility for varicose veins, I am not aware of any on its use in hemorrhoids. That said, Stanley Jacob (the pioneer of DMSO) reported successfully treating hemorrhoids with DMSO,121 another DMSO author (who studied under Jacob) also uses DMSO to treat hemorrhoids,122 and Merck reported it improved recovery after their surgical removal.123

Lastly, I was recently sent pictures showing two different people’s leg before DMSO and then 24 hours after:124,125

https://media.mercola.com/ImageServer/public/2024/December/dmso-legs.jpg
https://media.mercola.com/ImageServer/public/2024/December/dmso-veins.jpg

Wound Healing
DMSO is highly effective in healing tissue throughout the body. For example:

A veterinary study showed DMSO applied to open horse wounds promoted healthy granulation, reduced excessive growth, and disinfected contaminated wounds without pus formation.126
It accelerates wound healing in diabetic and nondiabetic mice127 and enhances tissue regeneration in burned skin.128 DMSO even speeds up the regeneration of lost limbs in newts by 2 to 3 days.129
A 1998 Russian study found that DMSO accelerates surgical wound healing and provides infection control, consistent with other studies on its effectiveness in wound recovery.130
A large number of studies also show that DMSO can prevent surgical incisions from developing adhesions or keloid scars, and in many cases reduce or eliminate scars.131
Ulcers
DMSO’s ability to both heal tissue and restore tissue blood supply (e.g., it frequently treats Raynaud’s disease132) makes it uniquely suited to treat challenging chronic nonhealing ulcers:

•A study evaluated the use of local DMSO for 20 diabetics with peripheral neuropathy and perforating foot ulcers. Complete healing occurred in 14 (70%) patients after 4 to 15 weeks of daily treatment, whereas in controls receiving conventional treatment, only 2 out of 20 recovered.133

•A study reported on the 1371 Chilean dermatologic patients they treated over 22 months who received a DMSO spray also containing other pharmacologic agents.134

skin affections treated
Of those patients (many of whom had not responded to years of treatment), 1,313 (95.04%) were completely restored or cured, and the patients were enabled to return to their usual activities — a dramatic effect that could not be obtained by any other available therapy. The other 4.96%, for various reasons, prematurely suspended treatment, and hence were no longer possible to observe or assess.

Note: 100% of the burn patients recovered, with none having the deforming scars typically seen after severe burns.

•A systematic review found that DMSO had low toxicity and was beneficial for wound healing and analgesia (particularly with ulcers).135

Mixed Studies
Numerous studies evaluated DMSO’s effects on a variety of dermatologic conditions and hence cannot be grouped into a single category. A study of 152 patients136 found DMSO dramatically helped all of the following patient cases:

67 varicose ulcers

7 shingles

10 herpes simplex (on the penis or the face)

8 impetigo

42 pityriasis versicolor

6 ingrown toenails and infected nails (here the improvement was only temporary)

2 pityriasis rosea

3 first and second degree burns

4 skin grafts

The paper also included photographs of some of these results:

dmso herpes face
dmso varicose ulcer
Another study found137 DMSO helped most of the following cases:

Keloids and hypertrophic scars (16 out of 23)

Peyronie's disease (1 out of 3)

Dupuytren's contractures (6 out of 9)

Scleroderma and sclerodermic changes (7 out of 11)

Palmoplantar keratoderma (17 out of 21)

Infiltrative processes of the lower limbs (6 out of 9)

Granuloma annulare (3 out of 5)

Hypertrophic lichen planus (3 out of 4)

Common warts (2 out of 4)

Burns (4 out of 4)

Shingles and post shingles neuralgia (10 out of 11)

Fibromas (2 out of 2)

A veterinary practice also reported138 remarkable results for mammary gland engorgement, interdigital cysts, chronic inflammatory reactions to vaccinations, flea bite allergies and severe dermatitis of the nail bed.

Common Dermatologic Conditions
DMSO has also been shown to help a variety of other skin conditions including:

Hair loss — For over 40 years, DMSO has proven effective in stimulating hair growth by improving microcirculation and rescuing hair-producing cells,139 especially when used early in the process. It has also helped individuals experiencing hair loss due to chemotherapy.

Note: One of the most common hair loss treatments, finasteride, is quite toxic and if possible should be avoided.

Acne and eczema — DMSO has been reported to treat acne and reduce scarring,140 though no formal studies confirm this. Initial clinical guidance from Merck has noted positive results, and unpublished studies by Jacob showed improvement in 9 out 9 cases of dermatitis.141 DMSO has also been used to treat skin abscesses142 and pustular diseases.

Note: DMSO has also been found to treat suppurative (pustular) diseases.143,144

Psoriasis — Several studies have explored DMSO's use for psoriasis:

A 1967 study showed improvements with low concentrations, followed by a worsening (possibly due to an excessive DMSO dose).145
A 1973 study of 33 patients with severe psoriasis found that an extract of camptotheca nuts dissolved in 70% DMSO was a "quick, effective and convenient treatment," as a year later, 21 had a complete resolution of the disease, while the remaining 12 had greatly improved.146
A 1989 study found DMSO when combined with heparin treating persistent psoriasis plaques 54.3% had a complete resolution, 40% a partial, and 5.7% no benefit.147
A 2009 study found DMSO, combined with topical corticosteroids, was very effective in treatment-resistant plaque-type psoriasis and could completely clear it in 3 to 4 weeks.148
Note: Limited data also supports the use of DMSO for lichen planus and lichen sclerosis.149

Severe itching (pruritus) — DMSO has been found effective in treating itching caused by amyloidosis, with significant relief in about four weeks.150 It also had a 90% success rate for pruritus ani (anal itching).151

Mastitis — A few of my colleagues use topically applied DMSO to treat mastitis in lactating women. This use is supported by a double-blind study that applied topical DMSO to women with chronic cystic mastitis for one month.152

Note: Numerous studies have also found DMSO is also very helpful for bovine mastitis.153

Bites — DMSO is often helpful for insect, dog, and snake bites.154 It has been used to treat venom from pit viper bites, preventing sloughing and scarring.155

Skin growths and cancers — DMSO is reported to eliminate benign skin growths,156 such as seborrheic keratosis and skin tags. Users have found it effective in reducing mole size and improving keloid scars.157 Additionally, DMSO has been shown to have significant value in the treatment of skin cancer.

Conclusion
One of the major issues in medicine is that we are taught to view the body as an amalgamation of separate parts and each disease is hence viewed as an isolated condition (that often demands its own proprietary drug and its own specialist). In truth, there is a vast degree of interconnectedness to the body, and frequently, only a generalist who can grasp a full picture of the body can identify the actual cause of a patient’s illness.

In dermatology, there is some recognition of this, as while dermatologists are trained to diagnose over 3,000 different diseases,158 they also are taught that many specific skin lesions are representative of certain illnesses deeper inside the body (e.g., a cancer).

However, as I’ve shown here, I believe DMSO’s ability to treat so many different skin conditions goes a step further and indicates that many dermatologic illnesses should instead be viewed as symptoms of key disease processes that underlie a wide range of medical disorders — a view which has been held by many schools of natural medicine throughout history.

Fortunately, we may at last be at a point where this is changing, as the unsustainability of our healthcare system that causes it to cost more each year (currently over 17.3% of GDP)159 while simultaneously producing worse and worse health outcomes (currently America’s healthcare outcomes rank last amongst the affluent nations)160 is at last reaching the point it cannot be continued.

As such, there is now an interest in the Forgotten Sides of Medicine unlike anything I have seen in my lifetime, and it is my sincere hope things like DMSO’s incredible ability to treat the skin can open the doors to many of its other even more remarkable uses.

Author's note: This is an abridged version of a longer article that goes into greater detail on the points discussed here, how DMSO is used for each of the conditions mentioned (along with other integrative approaches we’ve found help many of those skin conditions), and provides guidance for personal DMSO use (e.g., dosing, therapeutic precautions and where to obtain it). That article and its additional references can be read here.

A Note from Dr. Mercola About the Author
A Midwestern Doctor (AMD) is a board-certified physician from the Midwest and a longtime reader of Mercola.com. I appreciate AMD's exceptional insight on a wide range of topics and am grateful to share it. I also respect AMD’s desire to remain anonymous since AMD is still on the front lines treating patients. To find more of AMD's work, be sure to check out The Forgotten Side of Medicine on Substack.


+ Sources and References
https://media.mercola.com/PDF/References/dmso-skin-care-dermatology-ref.pdf

[haroldsails]

DMSO, Red Light Therapy, Methylene Blue, plus The Frontline Doctors suggested supplements, and staying active as I close in on 80. I am throwing everything into my quest to stay out of the clutches of a system that betrayed our trust. I am not afraid of dying, but of losing my personal sovereignty to a system with dubious intentions. Harold

[onawah]

DMSO a Miraculous Therapy for Chronic Pain and Musculoskeletal Injuries
A Midwestern Doctor
Sep 29, 2024
https://www.midwesterndoctor.com/p/dmso-is-a-miraculous-therapy-for

(This very long article is the one that Dr. Mercola has been quoting in his several articles about DMSO.)


"•The standard approach for treating pain and musculoskeletal injuries typically involves giving NSAIDs (e.g., ibuprofen), and in more severe cases, opioids. Unfortunately, these drugs are extremely dangerous (e.g., each one kills tens of thousands of people each year), but nonetheless have remained the standard of care for decades.

•DMSO is a remarkably effective pain-killing agent, in many cases allowing individuals who’d been disabled for years by their pain (e.g., a failed spine surgery or severe arthritis—DMSO’s most popular use) to get their lives back. Furthermore, it can treat many types of pain other therapies do not work on (e.g., complex regional pain syndrome).

•DMSO is a highly effective therapy for healing wounds and creating healthy scars, making it particularly helpful for recovering from surgery.

•DMSO is incredibly effective for healing a wide range of acute and chronic musculoskeletal injuries (e.g., arthritis, headaches, neck and back strains, restless leg syndrome, sprained ankles, trigeminal neuralgia and numerous traumatic injuries). It typically has an 80-90% success rate and often has an instant and dramatic effect. This use was particularly popular with professional athletes, as it allowed many of them to quickly return to the field rather than be out for the rest of the season.

•In this article, I will review the scientific literature that explains how DMSO provides pain relief and healing, the vast body of evidence (comprising of thousands of patients) showing it indeed does, and our preferred DMSO home treatment protocols for pain, arthritis, and musculoskeletal injury (along with the best sources for procuring DMSO).

One of the curious facets of Western Medicine is that while money is always spent on “research,” whenever the occasional miracle drug comes out that works too well with a wide range of applications, it is inevitably consigned to the dustbin of history regardless of the data put forward for it.

In the first part of this series (which provides important context for this article), I listed the decades of evidence that demonstrates the simple (naturally occurring) chemical Dimethyl Sulfoxide (DMSO) is a remarkably safe drug that completely transforms the care of many challenging and insurmountable illnesses (e.g., strokes, severe head trauma, spinal cord injuries, amyloidosis, Down’s Syndrome and dementia).
Note: after publishing the first article, I received many correspondences from readers who said DMSO was life saving when they had a stroke, many more testimonials on Twitter, and a few stories where it was used to treat a pet’s stroke (e.g., this reader’s dog).

However, while each of these applications, particularly DMSO’s utility in strokes, would completely change medicine and how those lifelong illnesses affect our society (and were what drove many doctors to spend decades researching DMSO), none of that accounts for why DMSO took America by storm and campaigns were launched (that members of Congress eventually joined) to overturn the FDA’s embargo on DMSO.

Rather, it was because DMSO solved three of the most common problems in medicine:

•It quickly heals a wide variety of musculoskeletal injuries (e.g., those routinely experienced by professional athletes or a chronic back injury leading to partial disability).

•It effectively treats a variety of joint disorders (e.g., rheumatoid arthritis).

•It’s an extremely effective and very safe painkiller.

Because of this, it was miraculous for many with chronic pain and disability (e.g., from osteoarthritis or a failed spinal surgery), particularly since all other pain-killing medications have significant (and frequently lethal) side effects and worse still—often don’t even work.

Note: a key theme to consider throughout this article is the immense difference in toxicity between DMSO and its conventional alternatives (such as corticosteroids and gabapentin). For example, NSAIDS and opioids each kill tens of thousands of Americans each year, whereas in over 60 years of use by millions of people, DMSO has not been linked to a single death. Likewise, NSAIDS are the leading cause of drug induced hospital admissions (because they are toxic to the heart and small intestine and particularly toxic to kidneys and stomach), whereas a systematic review of all published DMSO studies found the side effects associated with DMSO (e.g., typically skin irritation or a garlic-like odor and occasionally nausea, vomiting or diarrhea ) were minor and transient. Likewise, it’s very easy to overdose on an NSAID or Opioid, whereas a meticulous human study found taking 90 days of DMSO at 3-30 times the standard dosage did not cause any toxicity and was well tolerated by the research subjects (whereas almost any other drug would be extremely dangerous at doses that high)."

Much more at the link

[onawah]

DMSO Transforms the Treatment of Infectious Diseases
Analysis by A Midwestern Doctor
January 17, 2025
https://articles.mercola.com/sites/articles/archive/2025/01/17/dmso-infectious-diseases.aspx?ui=8d3c7e22a03f5300d2e3338a0f080d2da3add85bca35e09236649153e4675f72&sd=20110604&cid_source=dnl&cid_medium=email&cid_content=art1ReadMore&cid=20250117&foDate=true&mid=DM1689555&rid=207437322

"Story at-a-glance
Dimethyl sulfoxide (DMSO) is a safe, naturally occurring substance with properties that make it effective for treating various medical conditions, including pain, injuries, wounds, strokes, spine injuries, autoimmune disorders, cancer, and internal organ diseases
DMSO has broad antimicrobial properties, protects against microbial toxins, combats antibiotic resistance, and helps deliver healing deep into the body to treat otherwise inaccessible infections
DMSO studies have generated evidence supporting its role in treating cancer and autoimmune disorders through its unique antimicrobial properties
DMSO is highly effective against viruses like herpes and shingles, as well as conditions like feline panleukopenia in cats
DMSO also proves valuable in treating persistent fungal and parasitic infections

Introduction
DMSO is a remarkably safe and naturally occurring substance (provided you use it correctly1) that rapidly improves a variety of conditions medicine struggles with — particularly chronic pain. For reference, those conditions included:

Strokes, paralysis, a wide range of neurological disorders (e.g., Down Syndrome and dementia), and many circulatory disorders (e.g., Raynaud’s, varicose veins, hemorrhoids), which I discussed here.

A wide range of tissue injuries such as sprains, concussions, burns, surgical incisions, and spinal cord injuries (discussed here).

Chronic pain (e.g., from a bad disc, bursitis, arthritis, or complex regional pain syndrome), which I discussed here.

A wide range of autoimmune, protein, and contractile disorders such as scleroderma, amyloidosis, and interstitial cystitis (discussed here).

A variety of head conditions, such as tinnitus, vision loss, dental problems, and sinusitis (discussed here).

A wide range of internal organ diseases such as pancreatitis, infertility, liver cirrhosis, and endometriosis (discussed here).

A wide range of skin conditions such as burns, varicose veins, acne, hair loss, ulcers, skin cancer, and many autoimmune dermatologic diseases (discussed here).

In turn, since I started this series, it struck a cord and I have received over 1400 reports of remarkable responses to DMSO many readers have had (compiled here).

This begs an obvious question — if a substance capable of doing all of that exists, why does almost no one know about it? Simply put, like many other promising therapies, it fell victim to a pernicious campaign by the FDA which kept it away from America despite decades of scientific research, Congressional protest, and thousands of people pleading for the FDA to reconsider its actions. Consider for example, this 60 Minutes program about DMSO that aired on March 23, 1980:

In the 1960s a miraculous treatment for chronic pain, traumatic injury, strokes and spinal cord paralysis was discovered that spread across America like wildfire—until the FDA buried it.

Here, 60 Minutes exposed the FDA using the same playbook they used throughout COVID-19. A🧵 pic.twitter.com/Bh0dcjNk5w

— A Midwestern Doctor (@MidwesternDoc) October 14, 2024
https://x.com/i/status/1845727169273868623

DMSO and Infectious Diseases
DMSO has a variety of unique therapeutic properties. Some of those make it incredibly well-suited to addressing microbial infections. For example:

•While nontoxic, it has an antiseptic effect that is harmful to microorganisms, especially the smallest ones. This property appears to be the most beneficial for herpes, shingles, and complex conditions with a microbiological component.

•It can remove the antibiotic resistance of bacteria. This is particularly helpful in widespread problematic infections that have gradually developed a resistance to many existing antibiotics (e.g., tuberculosis) and challenging infections that are not responding to antibiotics (e.g., ones that would otherwise require an amputation).

•It can deliver antimicrobial agents to areas that are typically difficult to reach (e.g., deep in a bone) and also directly to regions that would otherwise require a systemic application of the medication.

•It can increase circulation to many parts of the body, something which is often critical for resolving illnesses (as a healthy blood supply allows the immune system to enter and heal diseased areas). Likewise, pretreatment with DMSO has been shown to increase the immune system’s ability to resist a subsequent infection.

•Much in the same way DMSO protects cells from a wide variety of lethal stressors,2 it can also protect them from the harmful effects of bacterial toxins and can mitigate the toxicity of antimicrobial agents taken for a prolonged period.

In short, DMSO can transform the management of infectious diseases.

Shingles and Herpes
Since many people struggle with Herpes (HSV-1 or HSV-2) and Shingles (Herpes Zoster), especially the pain which follows shingles (known as post-herpetic neuralgia or PHN), DMSO has been extensively studied for these uses. In turn, DMSO was found to significantly improve those conditions (and canker sores3), particularly when combined with idoxuridine (IDU), an antiviral that has poor penetration into tissues (and hence does not work alone).

•Herpes simplex

◦A 1965 study4 used 1% IDU in 90% DMSO (and 10% distilled water) in 7 patients with severe cutaneous infections and noted significant improvement in all herpes cases, with the only side effect being slight skin irritation from the solution.

◦A 1966 RCT5 (randomized controlled trial) of 21 patients with recurrent herpes found DMSO halved the durations of outbreaks, and when given with 5% idoxuridine, cut it to a third (with similar results also found in a 1967 study6).

◦A 1983 study7 found that DMSO effectively brought acyclovir (ACV) into the skin, caused a moderate reduction in herpes lesions, and dramatically reduced them when combined with acyclovir.

◦A 1990 RCT8 gave 80% DMSO mixed with 15% IDU to 301 immunocompetent female patients. The duration of pain was reduced by 2.6 days and the healing time to normal skin by 2.3 days.

◦A 2002 cell study9 found 0.65% DMSO reduced herpes viral replication by 50%.

Note: DMSO also helps herpes fever blisters, and DMSO with IDU has been reported to be effective in treating HSV whitlow (herpes on the fingers).10

dmso herpes face
•Shingles and Post Herpetic Neuralgia (PHN)

◦In 1967, a German investigator reported DMSO yielded generally good results in 10 of 11 shingles and PHN cases11 (with similar results being found in another 1967 study12).

◦Two 1970 RCTs showed that IDU in DMSO was at reducing the duration of pain and healing in shingles.13 The patients were delighted, for the pain disappeared within a median of two days.

◦In 1971, Dr. William Campbell Douglass conducted a study of 41 patients with shingles and PHN of whom 73.3% had a good response to DMSO and 13.3% had a fair response.

◦A 1974 RCT14 of 118 shingles patients and a 1992 RCT15 of 171 shingles patients found DMSO and IDU significantly shortened the vesicular phase, healing time, and duration of pain, and it significantly improved post-herpetic neuralgia.

◦A 1981 trial of 46 shingles patients also confirmed the benefit of DMSO and IDU.16

DMSO and Bacterial Infections
DMSO has five key properties that make it effective in treating bacterial infections:

1.Increased bacterial membrane permeability — DMSO enhances bacterial membrane permeability,17 making bacteria more vulnerable to antibiotics, especially those targeting internal structures (e.g., penicillin). This is crucial for treating infections like tuberculosis, which has a tough outer barrier.

2.Direct bacterial breakdown — DMSO can dissolve bacteria, causing their contents to leak out and effectively neutralizing them.

3.Disruption of bacterial function — DMSO interferes with bacterial metabolism by blocking the production of essential membrane proteins, as shown in studies with E. coli.18

4.Improved circulation — DMSO enhances blood flow,19 which helps combat chronic infections often caused by impaired circulation.

5.Protection against bacterial toxins — DMSO mitigates the harmful effects of bacterial toxins, protecting cells from stress.

DMSO also enhances the immune response,20 contrary to concerns about immune suppression, and has been shown to increase resistance to infections like typhus.21

Common Microbes
DMSO has been extensively tested against common infectious bacteria (e.g., staph, strep, E. coli, pseudomonas), both by itself and in combination with antimicrobial therapies.

After a 196422 study showed DMSO inhibited the growth of bacteria, a 1967 study tested it against various microorganisms, and found at sufficient concentrations that DMSO caused those organisms to dissolve into a sediment.23

dmso bacteriostatic bactericidal effect
A 1969 study24 found that 75% DMSO was bactericidal (mainly by causing their internal contents to leak out), while 15% was sufficient to stop bacterial growth.

dmso e coli
DMSO and Head Infections
Since DMSO is effective in eliminating many common microbial infections, it has shown great promise in ENT (ears, nose, and throat) medicine, as many of those diseases result from infections with common bacteria and the inflammatory response to them (particularly since it is often challenging to get antibiotics to the site of the infection).

Much of this was demonstrated in the 1967 publication25 by an ENT doctor who observed that DMSO would often significantly calm inflammation from an infection in the head (including severe ones that were difficult to treat with antibiotics). He compiled all of his cases26 here:

dmso summary of cases
•Eye infections — DMSO can treat various eye conditions, including macular degeneration and eyelid inflammation. In a 1976 study,27 it was combined with antibiotics to successfully treat eye infections. Additionally, DMSO can resolve pink eye after just a few applications.28

•Sinusitis — DMSO helps open blocked nostrils quickly by reducing swelling and promoting tissue healing.29 Studies have shown DMSO significantly alleviates sinusitis symptoms, including one 1967 study30 where most patients had excellent results. It also enhances the effectiveness of antibiotics in treating rhinoscleroma,31 a rare nasal infection.

•Dentistry — DMSO is used in dentistry as a mouthwash, relieving gum pain32 and preventing bleeding. It can alleviate toothache pain and reduce swelling after dental procedures.33 Dentists have found it effective for treating infections and saving loose teeth from periodontitis.34 Many studies35 show DMSO helps improve gum health, treat pulpitis,36 and accelerate healing after tooth extractions.37

Tuberculosis
Despite over a century of work, Tuberculosis remains the world's most deadly microbe (e.g., in 2023, it was estimated38 to have killed 1.25 million people). This is mainly due to this tiny bacteria’s unique characteristics and high aptitude for developing antibiotic resistance.

Because of this, once the early DMSO researchers realized that DMSO could remove antibiotic resistance, their focus immediately went to tuberculosis. In turn, many lab studies39 have demonstrated DMSO’s utility for this challenging infection which has been corroborated in humans:

•A 1969 study40 of 32, 14 showed an absence of tuberculosis secretion and most showed improvement (e.g., reduced endobronchitis, perifocal infiltration and lung tissue destruction).

•A 1980 study41 used DMSO to treat children with pulmonary tuberculosis.

•A 1991 study42 found nebulized DMSO mixed with rifampin over 1 to 2 months was an effective treatment for 148 pulmonary tuberculosis and 18 obstructive bronchitis patients (e.g., it healed the destructive cavities caused by tuberculosis).

Bacterial Toxins
One of the primary reasons bacterial infections sicken and kill is because of the toxins they release. DMSO in turn, has been repeatedly shown to mitigate this. For example:

•DMSO has been shown43 to protect the duodenum from H. pylori induced chronic ulcers.

•In rats, DMSO was shown44 to create a dose dependent reduction in the fluid secretion and mucosal permeability triggered by C. difficile’s toxin (with its maximum inhibition occurring at a 1% concentration). Given how common C. difficile colitis is, this application of DMSO has great promise.

•DMSO was shown to protect cells45 from the shigella bacteria’s toxin46 (which causes severe diarrhea and bloody stools).

•Endotoxaemia occurs in response to bacterial lipopolysaccharide (LPS) entering the bloodstream. A 2008 study of 18 horses47 found DMSO reduced the fevers that followed artificially induced endotoxemia, suggesting DMSO’s utility in treating sepsis, particularly since, DMSO can protect cells48 from the damage LPS causes.

Note: One of the most important characteristics the early adopters of ultraviolet blood irradiation recognized about it was that UVBI could effectively neutralize toxins in the bloodstream (a property that saved a significant number of lives).

Challenging Infections
DMSO has shown promise for many other challenging infections:

Sepsis — DMSO has proven effective in treating septic complications, especially in heart attack survivors. A 1982 study49 showed its success even against antibiotic-resistant bacteria. In 1984 a Russian study50 confirmed DMSO accelerated recovery in critically ill septic patients, with one case of bladder infection improving after using DMSO.

Note: One author cited51 a case of a septic patient with a severe bladder infection who did not respond to antibiotics but recovered once he began taking one teaspoon of DMSO three times a day.

Lung infections — DMSO has treated chronic lung infections, with a 1975 study52 showing rapid recovery in infants with severe respiratory diseases when combined with antibiotics. A 2020 study53 reported that DMSO, combined with ceftriaxone, helped 31 lung abscess patients fully recover without recurrence.

Note: DMSO has also been repeatedly shown54 to effectively treat acute respiratory distress syndrome, a challenging lung condition that frequently follows severe infections and often requires ventilation.

Abdominal infections — DMSO, combined with antibiotics, has effectively treated peritonitis55 and abdominal abscesses.56 It helps concentrate antibiotics in the abdomen,57 providing extended treatment duration, especially for peritonitis, a fatal condition.

Meningitis

A 1978 study58 found DMSO was an effective treatment for meningococcal infections.
A 1987 study59 used DMSO combined with a nuclease to treat meningitis or meningoencephalitis caused by an acute viral respiratory infection.
Osteomyelitis — DMSO has shown significant results in treating bone infections.60 Studies have found that combining DMSO with antibiotics and other therapies like hyperbaric oxygen speeds up recovery and reduces bone damage in both acute and chronic osteomyelitis.61,62,63,64,65,66

Orchitis and epididymitis — In 1986, a Russian physician reported these conditions have an excellent response to DMSO.67

Cancer and autoimmunity — DMSO has been observed to eliminate the unusual bacteria associated with many cancers and autoimmune diseases, which may in part explain its utility for those conditions.

Note: A wealth of evidence also supports DMSO’s use in a variety of challenging veterinary infections.68

Surgery
Three of the major issues encountered in surgery are:

Surgical wounds (or burns) become infected before they seal and heal.
Infections deep within the body need to be cut open so the infection can be drained or removed (or have antibiotics directly applied to it).
Infected tissues must be removed (e.g., amputated) because the infection within them can’t be reached or addressed.
Fortunately, DMSO’s is uniquely suited to address each of these. For example, in this article, I discussed how many studies and reader testimonials show DMSO is a remarkable therapy for burns and wound healing, and here I reviewed the wealth of evidence that DMSO is a highly effective therapy for surgical scar healing.

Likewise, DMSO makes reaching a deep infection within the body possible without surgery. Numerous studies, in turn, demonstrate that DMSO can prevent and treat those infections:

A 1969 case report69 highlighted a patient with a chronic fungal infection (that has high resistance to antifungals) who declined amputation in favor of antifungals dissolved in DMSO which saved his foot.

Note: There are many other cases of DMSO curing a chronic infection that had required amputation.70

A 1978 surgical study71 used DMSO in combination with antibiotics to treat inflammatory infiltrates.

A 1984 study72 used DMSO to treat surgical wound infections.

A 1985 study73 found that injecting DMSO after severe mechanical trauma reduces the risks of a subsequent infection, while a 1984 study74 found that DMSO plus antibiotics prevent open wounds in the hands from developing purulent infections.

A 1990 study75 of 33 patients with phlegmons (inflamed areas under the skin) throughout the body found that a dressing with DMSO and silver nitrate, when compared to those receiving standard treatments, reduced the time required to begin a surgical repair by 2 to 2.5 times.

In 1998, Russian physicians reported that they routinely apply DMSO to surgical wounds as it accelerates healing and provides general infection control.76

Fungal Infections
A 2013 study77 used DMSO and antifungal agents on six different Candida species. It found 0.5% to 1% DMSO had an antifungal effect, but the inhibitory effect (with or without concurrent antifungals) varied significantly.

DMSO can also effectively bring antifungals to many parts of the body. DMSO for instance was shown78 to significantly increase the amount of ketoconazole that enters the brain and can transport griseofulvin79 through the skin (which in a 1974 study80 was used to successfully treat ringworm). Additionally:

A 1965 study81 found DMSO was an effective treatment for ringworm and athlete’s foot, especially when combined with an antifungal.
A 1977 study82 found DMSO (in combination with lidase) was a highly effective treatment for actinomycosis of the face and neck.
A 1997 study83 found DMSO mixed with itraconazole treated fungal infections in horse corneas.
Parasites
There is also some data on how DMSO can treat parasites (e.g., 3% DMSO has been shown to significantly inhibit the growth of Trypanosoma cruzi,84 which causes Chagas disease). However, its primary value is bringing an antiparasitic medication to the region of infection (as parasites can often burrow quite deep into the tissues).

For example, two different 1966 studies (this study85 and this 25 person RCT86) found that DMSO plus an antiparasitic (e.g., 2% topical thiabendazole in 90% DMSO) was an effective treatment for hookworm infections in the skin. DMSO can also be combined with antiparasitic medications to reach challenging parasitic infections deep within the body. For example, a 1984 case report87 discussed DMSO treating a complex amoeba infection of the liver.

Conclusion
Many who’ve worked with DMSO believe it should be routinely utilized for severe infections, particularly those not responding to antibiotic therapy. Fortunately, we are in a unique moment where these forgotten sides of medicine finally have a chance to see the light of day.

Thus, I sincerely hope articles like these can begin to shift the medical system towards adopting a more sophisticated approach to infectious diseases that can help patients struggling with challenging infections.

Author's Note: This is an abridged version of a longer article that goes into greater detail on the points discussed here and provides guidance for personal DMSO use (e.g., dosing, therapeutic precautions and where to obtain it) along with other natural approaches we’ve also found help many of those conditions (e.g., herpes and shingles). That article can be read here.

A Note from Dr. Mercola About the Author
A Midwestern Doctor (AMD) is a board-certified physician from the Midwest and a longtime reader of Mercola.com. I appreciate AMD's exceptional insight on a wide range of topics and am grateful to share it. I also respect AMD’s desire to remain anonymous since AMD is still on the front lines treating patients. To find more of AMD's work, be sure to check out The Forgotten Side of Medicine on Substack."

[onawah]

How DMSO Makes Cancer Treatments More Effective and Much Less Toxic
Analysis by A Midwestern Doctor
May 02, 2025
https://articles.mercola.com/sites/articles/archive/2025/05/02/how-dmso-makes-cancer-treatments-more-effective.aspx

https://media.mercola.com/ImageServer/Public/2025/May/PDF/how-dmso-makes-cancer-treatments-more-effective-pdf.pdf

(Hyperlinks in the article not embedded here.
Personally, I have little interest in pharmaceuticals or chemotherapy, but at the end of this article, there is info about DMSO used in combination with natural substances, and more about why the efficacy of DMSO has been covered up. I've put that part in bold letters.)

"Story at-a-glance


Versatile therapeutic benefits — Dimethyl sulfoxide (DMSO) is a potent compound known for treating a wide range of conditions, including chronic pain, stroke recovery, tissue damage, autoimmune disorders, various skin conditions, and complex infections
Unique role in cancer care — DMSO’s distinctive properties enable it to support the body in combating cancer while safeguarding healthy cells from the harmful effects of chemotherapy and radiation
Enhanced chemotherapy delivery — When paired with chemotherapy, DMSO improves the drug’s ability to penetrate cancer cells that are typically inaccessible, significantly boosting treatment effectiveness
Lower doses, reduced toxicity — By enhancing the potency of chemotherapy, DMSO allows for the use of lower doses, substantially reducing the toxic side effects associated with conventional cancer treatments
Synergistic potential — DMSO demonstrates promising results when combined with various pharmaceutical agents, amplifying their cancer-fighting capabilities


DMSO is a naturally occurring substance that has a variety of unique properties that have immense therapeutic potential. In turn, thousands of studies show DMSO safely treats a wide range of:

•Injuries such as sprains, concussions, burns, surgical incisions, and spinal cord trauma — discussed here.

•Strokes, paralysis, many neurological disorders (e.g., Down syndrome and dementia), and numerous circulatory disorders (e.g., Raynaud's, varicose veins, or hemorrhoids) — discussed here.

•Chronic pain (e.g., from a bad disc, bursitis, arthritis, or complex regional pain syndrome) — discussed here.

•Many autoimmune, protein, and contractile disorders such as scleroderma, amyloidosis, and interstitial cystitis — discussed here.

•Head conditions including tinnitus, vision loss, dental problems, and sinusitis — discussed here.

•Internal organ diseases such as pancreatitis, infertility, liver cirrhosis, and endometriosis — discussed here.

•A wide range of skin conditions such as burns, varicose veins, acne, hair loss, ulcers, skin cancer, and many autoimmune dermatologic diseases — discussed here.

•Many challenging infections such as shingles, herpes, chronic ear or dental infections, and osteomyelitis — discussed here.

Sadly, once the FDA realized the extent to which DMSO would transform medicine, the agency made the decision to erase it from history. As a result, millions of patients whom it helped and the thousands of studies on its therapeutic potential have been largely forgotten. Consider for example, this 1980 60 Minutes program:



A Midwestern Doctor
@MidwesternDoc
In the 1960s a miraculous treatment for chronic pain, traumatic injury, strokes and spinal cord paralysis was discovered that spread across America like wildfire—until the FDA buried it.
Here, 60 Minutes exposed the FDA using the same playbook they used throughout COVID-19. A🧵
2:23 AM · Oct 14, 2024
1.5M Views
1845727169273868623
Fortunately, because DMSO is effective for a wide range of conditions, it's caught on like wildfire over the last six months (e.g., I've already received over 2,000 reports of remarkable responses to DMSO, many for a variety of "incurable" conditions).

@DoctorMercola:2/DMSO-A-Natural-Compound%27s-Potential-in-Cancer-Treatment:a

Potentiating Chemotherapy

Due to the controversy around DMSO, its pioneers chose to downplay its anticancer potential to avoid backlash against "unproven" treatments. As a result, its cancer-fighting properties remain largely unknown. For example, earlier in this series, I presented hundreds of studies that show:

•DMSO effectively treats cancer pain (which is often very challenging to address).

•Dramatically reduces many of the complications experienced from radiation therapy and chemotherapy.

•DMSO stops cancers from growing.

•DMSO causes cancerous cells to transform back into normal cells.

One of DMSO's well recognized properties is its ability to dissolve a wide range of other substances and transport them throughout the body thereby allowing topical applications of medications that would otherwise require injection once they are dissolved in DMSO.

More importantly, once inside the body, DMSO allows substances it has dissolved to reach otherwise inaccessible places within the body (e.g., a chronic infection within the bones) and to enter cells that have shielded themselves from medications (e.g., DMSO has been shown to remove the resistance many bacteria have to antibiotics).

Many of these same challenges exist with treating cancer. Fortunately, in the same manner DMSO increases the potency of many antimicrobial therapies, it does the same for chemotherapy. This is extremely important because:

•It increases the likelihood that a cancer therapy protocol will be successful, particularly in resistant cancers.

•It allows lower chemotherapy doses to be used, which significantly decreases the toxicity to normal cells and thereby addresses one of the largest issues with conventional cancer treatments.

For example, since the blood-brain barrier shields brain cancers from chemotherapies, higher (toxic) chemotherapy doses need to be used to treat those cancers.

In turn, since DMSO passes through the blood brain barrier and concentrates inside tumors (e.g., one study found DMSO had a 1.5X increase in brain tumors1 while another found it can detect brain tumors that cannot be detected with conventional contrast agents),2 independent physicians have mixed chemotherapy with DMSO to treat brain cancers.3

Note: Since the toxicity of normal doses of chemotherapy is such a pressing issue, a variety of approaches have been developed over the years to increase its potency (a few of which we've found to be very helpful). One of the most well-known approaches is insulin potentiation therapy, which uses the higher concentrations of insulin receptors cancer cells have to trick cancer cells into consuming more of the chemotherapy.4,5

Cytoplasmic Barriers
One of the major issues with treating cancers is that cancer cells can become resistant to chemotherapy. After observing that cancerous epidermal cells (unlike normal cells) were able to resist cytotoxic (chemotherapy) drugs entering them by creating a fibrin-like "cytoplasmic barrier," three different studies discovered that mixing the drugs with DMSO allowed them to penetrate cancerous cells.6,7,8 Furthermore:

•Another study found that cancer cells had a disordered cytoskeleton (which is now well recognized) and an impermeable barrier around the cell that resisted chemotherapy drugs from entering.9

https://media.mercola.com/ImageServer/Public/2025/April/polarized-light-cytoskeleton.jpg

When DMSO was added, it allowed cytoskeleton-targeting drugs to enter the cells and dramatically increased their potency (e.g., making a dose of 1/30th to 1/1000th of their usual dose needed).10

•A later 2022 study found that 1% DMSO significantly altered the cytoskeleton of melanoma cells (e.g., how they attached to their extracellular surroundings) but not normal cells,11 and that when DMSO was combined with CaS (which releases ions that can trigger programmed cell death), the there was no noticeable effect on the skeleton of normal cells, but there was heavy disruption to the cytoskeleton of cancerous cells.

https://media.mercola.com/ImageServer/public/2025/April/dmso-cell-control.jpg

Cancer Treatment Studies
Many animal and human studies (which I compiled here) have also demonstrated that DMSO enhances the potency of chemotherapy. For example:

•A 1975 study of 65 patients with incurable cancers (most of which had received conventional therapies) were injected with a low dose of cyclophosphamide mixed in DMSO with GABA, GABOB, and acetylglutamine.12

Objective or subjective remissions were obtained in 57 of the 65 patients (e.g., many went from being in extreme pain to being pain free), and almost all of those with lymphomas or breast cancers had complete recoveries, while about half of those with other incurable cancers recovered.

https://media.mercola.com/ImageServer/public/2025/April/incurable-cancers-recovered.jpg

Note: This study also found that patients who could not otherwise tolerate cyclophosphamide were able to with DMSO.

•A 1975 rat study found that oral DMSO increased the potency of cyclophosphamide,13 which in turn required lowering the cyclophosphamide dose to avoid creating toxicity (which the authors felt could potentially make a safer and more effective dosing regimen for cyclophosphamide).

They also found DMSO increased the survival times in advanced cancers by potentiating the following drugs 6-mercaptopurine, Methotrexate, Chlorambucil, Vinblastine, Procarbazine, CCNU, MCCNU, BCNU, Daunomycin, Nitrogen mustard, Dianhydrogalactitol, Norbornyl, and Adriamycin.

In contrast, no benefit was seen with cytosine arabinoside, vincristine, and 5-fluorouracil, all of which did not have the lowered toxicity threshold observed with cyclophosphamide.

Note: An ambitious follow-up project was made to test various other anticancer drugs. However, just as clinical trials were scheduled to start, they were halted by a jurisdictional dispute within the FDA.14

•A follow-up 1983 study then determined that DMSO did not increase the toxicity of any chemotherapy drug, but with oral administrations, did temporarily increase (for 2 to 3 hours) its initial levels in the body, thereby increasing their effectiveness.15 It also found that DMSO being added reduced the overall growth of the tumors and that certain cancers had a higher response to DMSO being added in than others.

•A 1987 study of patients with cervical cancer found that applying metronidazole dissolved in DMSO to the cervix increased the tumor's regression following radiation therapy.16

•A 1988 study provides the most detailed data on how DMSO potentiated chemotherapy agents (particularly against breast cancers) along with shedding light on the innate anticancer activity of DMSO:17

/https://media.mercola.com/ImageServer/public/2025/April/anticancer-activity-of-dmso.jpg

Note: A follow-up study by those authors found that 10% DMSO greatly enhanced the potency of a variety of anticancer drugs on ovarian cancer cells.18

•In rats treated for bladder cancer with doxorubicin, adding 10% DMSO caused a 7.1 fold increase in bladder concentration (while 50% caused a 12.1 fold increase) and a 9.3 to 9.6 fold increase in the lymph nodes. Mixing doxorubicin in 5% DMSO reduced the amount of doxorubicin needed to eliminate cancer by 44%.19

•A 2021 Ukrainian study of 52 patients with bladder cancer who had it surgically removed found that giving intravesical DMSO in conjunction with chemotherapy significantly reduced the 5-year recurrence, and there were no side effects from doing so.20

https://media.mercola.com/ImageServer/public/2025/April/relapse-rates-in-groups.jpg

Specific Chemotherapies
•Cisplatin studies — One of the most extensively tested DMSO combinations is with cisplatin, a drug that has shown significant promise for pairing with DMSO. However, it is also a concern because DMSO can bind to platinum-containing drugs (such as cisplatin, carboplatin, and oxaliplatin) and partially inactivate them.21

However, when tested in cell cultures and animals, DMSO typically increases the efficacy and reduces the toxicity of Cisplatin (but in some cases reduces Cisplatin's efficacy). For example:

◦In a 1982 study of dogs with bladder cancer, mixing DMSO with cisplatin caused a threefold increase in how much was absorbed into the bladder muscle22 (which is similar to what this study found).23

◦A 1991 rat study found that giving DMSO with cisplatin reduced its kidney toxicity (and weight loss) but did not reduce its toxicity to carcinosarcoma.24

◦A 1995 study of rats with experimentally induced bladder cancer found that combining DMSO with cisplatin decreased the depth of cancer invasion compared to cisplatin alone or to placebo.25

◦A 2008 study found that mixing cisplatin with DMSO reduced both its neurotoxicity and toxicity to cancer cells,26 with the decrease in neurotoxicity being approximately twice the reduction in cancer cell toxicity. It also significantly decreased cisplatin's toxicity to the kidneys and slowed its elimination from the body.

◦A 2015 mouse study showed DMSO reduced the kidney toxicity of cisplatin, increased its reduction in tumor size,27 and increased the survival time in animals who received it. Likewise, another study found that DMSO increased cisplatin's efficacy and decreased its toxicity.28

◦A 2019 study found that DMSO doubled the toxicity of cisplatin to lung cancer cells (thereby making a much lower therapeutic dose needed) and reduced the cancer cells' resistance to chemotherapy drugs.29

•Other chemotherapy studies — DMSO has also been shown to enhance the efficacy of a variety of other cancer drugs:

◦A 1986 study found DMSO increased acute lymphocytic leukemia (ALL) sensitivity to nitrogen mustard in a dose-dependent fashion (the compound cyclophosphamide is derived from).30

◦A 1989 study found that DMSO enhanced the ability of cisplatin, 5-FU, and cyclophosphamide to slow aggressive (implanted) prostate cancers.31

◦A 1994 case report detailed two AIDS patients with Kaposi's sarcoma who were successfully treated with topical DMSO mixed with bleomycin, with no toxicity being observed.32

◦A 1998 study found that DMSO increased the potency of 5-fluorouracil and doxorubicin.33

◦A 2001 study found that DMSO induced differentiation in human breast cancer cells and increased their sensitivity to doxorubicin.34

◦A 2004 study found that DMSO caused a 71.7% growth inhibition of breast cancer cells at 96 hours and improved the safety and efficacy of the cancer drug gemcitabine.35

◦A recent study found that DMSO significantly reduced the growth of prostate cancer cells, and this effect increased when it was given concurrently with nelfinavir.36

Lastly, DMSO when combined with 5-fluorouracil (5-FU), has repeatedly been found to treat skin cancers and warts. For example, a 1967 study found DMSO significantly increased 5-FU's potency and made 5% able to locally treat keratoacanthoma, superficial basal cell, and early stage squamous cell carcinoma without causing any adverse effects37 and likewise, this study used DMSO to enhance 5-FU's ability to treat seborrheic keratosis.38

•Photodynamic therapy — Photodynamic therapy works by combining a photosensitizer (e.g., 5-ALA) with light in tumors, generating a reactive chemical that destroys the cancer. DMSO has also repeatedly been found to enhance this treatment:

◦A 1995 study found that mixing 5-ALA with 2% EDTA and 2% DMSO eliminated 85.4% of basal cell carcinomas (BCC) in 48 patients, 100% of superficial squamous cell carcinomas (SCC) in 5 patients, partially improved 2 ulcerated SCCs, and overall to more than double the response to 5-ALA photodynamic therapy.39

◦Another 1995 study treated 763 BCCs in 122 patients, using either 5-ALA, 5-ALA with DMSO as a pretreatment, or 5-ALA plus DMSO plus EDTA. DMSO plus EDTA was shown to improve 5-ALA penetration depth significantly, doubled ALA-induced porphyrin production (a key part of photodynamic therapy), and almost doubled the response to treatment.40

◦A 2009 study found DMSO plus 5-ALA photodynamic therapy entirely eliminated 55 out of 60 basal cell cancers (with a good cosmetic outcome), of which 81% did not recur after 6 years (with 91% not recurring if two rather than one treatment was given).41

◦In another 2009 study, 19 cases of Bowen's disease (early SCC) and 15 BCCs received a single course of photodynamic therapy with DMSO and EDTA. At 3 months, 91.2% of the tumors were gone, while at 60 months, 57.7% of Bowen's disease and 63.3% of BCCs had not recurred.42

•Other pharmaceutical combinations — Other (less toxic) drugs have also shown promise for cancer when combined with DMSO. For example:

◦Since cervical cells can easily be gently scraped off and examined, a team of researchers evaluated how a variety of substances caused them to transform into cancers or caused cancerous cells to differentiate into normal cells.43

From this, they found that while DMSO alone did very little, if it was combined with a small amount of dexamethasone, within 2 to 3 weeks, it rapidly transformed the cancerous cells (e.g., carcinomas in situ or metastatic cervical cancers lesions) to normal ones and healed the surrounding tissue (e.g., malignant tissues, typically red, granular, and friable, became smooth, pink, and resilient with diminished bleeding and vascularity), and at the time of publication, reported successfully treating six out of six patients, including one with metastatic cancer.

Note: DMSO in combination with colchicine has also been used to treat skin cancer.44

◦A 2015 study found that DMSO significantly increased the toxicity of organotin polyethers on various cancer cells.45

◦One approach to eliminating cancer is using a magnetic molecule that can be heated with a magnetic field. When a 2021 study attached that substance to DMSO,46 it was found to be an effective treatment for cervical cancer and significantly enhance the potency of the cancer drug carmustine.47

Note: There are also many papers that found DMSO containing drugs (e.g., ruthenium-based ones) effectively eliminate cancers48 and in some cases will selectively target metastatic tumors.49

Natural Combination Therapies
In the same way that DMSO potentiates chemotherapy, it can also enhance the effects of natural compounds. For example:

•A 1969 study found that DMSO, when combined with heat and vitamin A, selectively targeted cancer cells.50

•A 2018 study found that DMSO and a plant extract selectively arrested cell growth and induced cell death of colon cancer cells.51

•A 2023 study found that when fatty acids were isolated from the urine of healthy cows and mixed with DMSO, it was an effective therapy against breast cancer cells.52

Currently, I believe the most promising use of DMSO is to potentiate a natural therapy, as these compounds have minimal toxicity (so little risk exists when potentiating them). Some of the most extraordinary benefits I have seen from DMSO combination therapy came from combining it with a natural therapy, which was known to be effective against cancer.

For example, numerous clinical trials have shown that when DMSO is combined with baking soda,53 it not only treats cancer but also significantly decreases the pain and symptomatology experienced from advanced cancers being treated with chemotherapy, with these benefits greatly exceeding those available in the existing medical arsenal. Likewise, other natural therapies used to treat cancer (e.g., vitamin C) have also demonstrated synergistic efficacy with DMSO.

Since there are so many potential combinations with DMSO, most of them have never been tested, and many synergistic combinations remain to be discovered. Fortunately however, one remarkable one has been, DMSO mixed hematoxylin (a dye commonly used in pathology, which like DMSO, comes from a tree).

This combination selectively targets cancer cells (as it will only stain cancerous tissues once injected), has virtually no toxicity, and over the decades has shown a success rate of between 80% to 90% in treating a variety of otherwise challenging (and often "incurable") cancers.

Note: This combination was discovered roughly 60 years ago, but despite the FDA receiving remarkable data on its safety and efficacy over the years, like many other promising cancer cures, it was buried. Fortunately, an underground network of practitioners kept the treatment alive, and recently one doctor who spent fifteen years refining the therapy shared all of his remarkable data with me (which is discussed here).

Conclusion
The practice of medicine is shaped by a set of deeply ingrained assumptions — many of which can be harmful to patients. For example, the blanket belief that all vaccines are "safe and effective" persists despite a vast body of evidence linking childhood vaccinations to a wide range of chronic illnesses.

In oncology, one such assumption is that cancer is an unstoppable disease that demands brutal treatments merely to offer a chance at survival. As I've aimed to show here, this belief rests on a shaky foundation, as even when conventional cancer therapies — often highly toxic — are deemed necessary, their damaging effects can be significantly reduced when combined with compounds like DMSO (while simultaneously their efficacy can be increased).

The medical establishment's excessive greed and overreach during the COVID-19 era opened many eyes, leading people to question long-held narratives. If effective treatments for COVID were actively suppressed, it's only natural to wonder: could the same be true for cancer?

This wave of critical thinking helped spark the Make America Healthy Again (MAHA) Movement, which is now working to overturn decades of harmful public health policies that have consistently prioritized profit over people. I believe we are facing a once-in-a-lifetime opportunity to reexamine the flawed foundations of modern medicine — and that this series has shown how a single, overlooked compound could dramatically reshape the way we treat cancer.

Author's Note: This is an abridged version of a longer article that reviews the point mentioned here in more detail. It also discusses how DMSO reduces cancer pain, the complications of radiation therapy and chemotherapy, and how it greatly enhances the effectiveness of both conventional and natural cancer treatments.

That article (along with guidance for using DMSO) can be read here. Additionally, a companion article on how DMSO and a natural dye can transform cancer treatment can be read here.

A Note from Dr. Mercola About the Author
A Midwestern Doctor (AMD) is a board-certified physician from the Midwest and a longtime reader of Mercola.com. I appreciate AMD's exceptional insight on a wide range of topics and am grateful to share it. I also respect AMD's desire to remain anonymous since AMD is still on the front lines treating patients. To find more of AMD's work, be sure to check out The Forgotten Side of Medicine on Substack."

- Sources and References
1, 2 NMR Biomed., 26: 173-184
3, 5 Beulah Land Press, 2002 (Archived)
4 Iptq.com (Archived)
6 Naturwissenschaften 56, 465 (1969)
7 Annales Medicinae Experimentalis et Biologiae Fenniae, 01 Jan 1969, 47(4):253-258
8 Acta radiologica. Supplementum, 01 Jan 1971, 307:1-222
9 Ann N Y Acad Sci. 1983:411:372-4
10 Wikipedia, Cytoskeletal Drugs
11 The FASEB Journal, Volume 36, Issue 1, May 2022
12 Annals of the New York Academy of Sciences, 243: 412-420
13 Ann N Y Acad Sci. 1975 Jan 27:243:194-208
14 Amazon, The Persecuted Drug: The Story of DMSO
15 Ann N Y Acad Sci. 1983:411:150-60
16 Med Radiol (Mosk). 1987 Feb;32(2):35-7
17 Am J Surg. 1988 May;155(5):672-6
18 American Journal of Obstetrics and Gynecology, Volume 159, Issue 4, October 1988, Pages 848-852
19 JNCI: Journal of the National Cancer Institute, Volume 84, Issue 7, April 1992, Pages 510–515
20 Pharmacology Online Archives, 2021, Volume 2, 690-698
21 Cancer Res (2014) 74 (14): 3913–3922
22 The Journal of the American Osteopathic Association, Volume 83, Number 4, 1983, Pages 103-106
23 The Japanese Journal of Urology 84 (5), 961-, 1993-05-20
24 Anticancer Research, 01 Sep 1991, 11(5):1939-1942
25 The Japanese Journal of Urology, 1995, Vol. 86, No. 1, p. 175
26 NeuroToxicology, Volume 29, Issue 3, May 2008, Pages 444-452
27 Cancer Cell Int 15, 104 (2015)
28 Chemosensitizing and Nephroprotective Effect of Dimethyl Sulfoxide in Cisplatin Treated Animals, Accessed April 2025
29 International Journal of Pharmacology, Year: 2019 | Volume: 15 | Issue: 5 | Page No.: 586-592
30 International Journal of Radiation Oncology* Biology* Physics, Volume 12, Issue 7, Part 1, July 1986, Pages 1165-1169
31 The Prostate, Volume 15, Issue 3, 1989, Pages 221-232
32 Acta Derm Veneriol (Stockh) (74)
33 Breast Diseases of the Senologic-International-Society, OPORTO, Portugal, 31 May - 04 June 1998, Pages 605-611
34 Chin. J. Cancer Res. 13, 27–30 (2001)
35 Neoplasma, 51, 6, 2004
36 DeBusk College of Osteopathic Medicine, Lincoln Memorial University (LMU-DCOM)
37, 38 Annals of the New York Academy of Sciences, Volume 141, Issue 1, March 1967, Pages 428-436
39 Journal of Photochemistry and Photobiology B: Biology, Volume 28, Issue 3, June 1995, Pages 213-218
40 Proceedings Volume 2371, 5th International Photodynamic Association Biennial Meeting; (1995)
41 J Eur Acad Dermatol Venereol. 2009 Jan;23(1):58-66
42 Photodiagnosis Photodyn Ther. 2009 Sep-Dec;6(3-4):207-13
43 Annals of the New York Academy of Sciences, 141: 414-422
44 Vestn Dermatol Venerol. 1980 Oct:(10):59-61
45 Journal of the Chinese Advanced Materials Society, 1(4), 294–304
46, 47 Journal of Nanoscience and Nanotechnology, Volume 21, Number 12, December 2021, pp. 6196-6204(9)
48, 53 The Forgotten Side of Medicine, March 15, 2025
49 Drug Invest 8, 150–161 (1994)
50 Archiv fur Geschwulstforschung, 01 Jan 1969, 33(4):331-344
51 Nutrition and Cancer, 71(7), 1181–1188
52 Biomedicines 2023, 11(3), 889

[Mike]

How much DMSO should an averaged sized person take daily, if taken orally? Roughly?

It's mixed with water, correct?

[onawah]

I have only used it topically, and I can't imagine ingesting it. Topically, it itches and burns a LOT for about 15 minutes after applying.
But it may come in a different form than the liquid that can be purchased over the counter, if it's meant to be taken orally, or to be injected.
I would be very careful, until you know for sure.


How much DMSO should an averaged sized person take daily, if taken orally? Roughly?

It's mixed with water, correct?

[Mike]

I have only used it topically, and I can't imagine ingesting it. Topically, it itches and burns a LOT for about 15 minutes after applying.
But it may come in a different form than the liquid that can be purchased over the counter, if it's meant to be taken orally, or to be injected.
I would be very careful, until you know for sure.


How much DMSO should an averaged sized person take daily, if taken orally? Roughly?

It's mixed with water, correct?


I had some liquid DMSO a while ago, and the book posted by Paula, but I never earnestly gave it a shot (and God knows where that book is now).

Now I want to give it a shot, and am looking for some basic instructions if anyone can provide them.

[leavesoftrees]

I have only used it topically, and I can't imagine ingesting it. Topically, it itches and burns a LOT for about 15 minutes after applying.

The DMSO I use doesnt itch and burn - bought off Amazon from Germany. Maybe you have a sensitivity to it or there is something not right with the product you are using

I make a formula of equal parts
CBD infused coconut oil
DMSO
Emu oil
Castor oil
Apply to affected joints deeply massaging into the joint. Excellent for arthritis

[meat suit]

I have only used it topically, and I can't imagine ingesting it. Topically, it itches and burns a LOT for about 15 minutes after applying.

The DMSO I use doesnt itch and burn - bought off Amazon from Germany. Maybe you have a sensitivity to it or there is something not right with the product you are using

I make a formula of equal parts
CBD infused coconut oil
DMSO
Emu oil
Castor oil
Apply to affected joints deeply massaging into the joint. Excellent for arthritis

I think itchyness is an individual thing..
I use a 70%dmso/30% aloe vera gel topically.
I am the only one in my family that gets itchy from it, and only when applied to my back.
My arms, legs etc. dont itch...

[onevoice]

I saw this video a few days ago. I really liked her presentation and the simplicity of her formula. She says basically to use 2 parts castor oil with 1 part DMSO. There are other variation she states as well. I liked that she focuses on dealing with neuropathy as my wife has it as well and will try this formula as soon as possible.
SjopkuUuacQ

[Harmony]

Mike, we have another thread about DMSO too that you might find the information you need :heart:
DMSO for Eyes: Glaucoma, Cataracts, Strain, Vision, Retinitis and the Organ Responsible for Eye Care (https://projectavalon.net/forum4/showthread.php?119909-DMSO-for-Eyes-Glaucoma-Cataracts-Strain-Vision-Retinitis-and-the-Organ-Responsible-for-Eye-Care)

[silver birch]

No PUN intended as I know we have very few mouse brains as members. :cat:

According to all-knowing Wikipedia ... ,
"DMSO exposure to developing mouse brains can produce brain degeneration. This neurotoxicity could be detected at doses as low as 0.3 mL/kg, a level exceeded in children exposed to DMSO during bone marrow transplant.[53] "

So, if you are around 80 kg, the limit is 24 ml pure DMSO.


The problem with itching and pain, and regarding internal use, the potential risk of hurting mucous membranes, is mainly a result of the quick heating and reaction when undiluted DMSO is applied to some tissue containing water.

Commercial preparations tend to not be stronger than about 50% relative to water content.
As DMSO do not dissolve oils, they have minor reduction in the irritability.




My latest use is with Hematoxylin, that is the red dye from wood, attaching to some cancer cells and killing them
in combination with DMSO.


I took :

2 g of the purest Hematoxylin powder i could find, that is, 97%+
150 ml sterile water (let cool, not to heat upp too much when mixed with DMSO)
1 tea spoon Carragenan iota dissolved in the cool water and then heated again to 70 deg C
(let cool, not to heat upp too much when mixed with DMSO)
150 ml 99.9% DMSO

Mix well and store in glass jar in the fridge. (Carragenan iota is anti-virus and -bacterial, and gives a gel, making it easier to eat without colouring everything)

Took orally 5 ml three times a day until jar empty.

The taste is sweet. Can of course be mixed with drink too.


After a few days, I could feel some birth-marks itching, and then falling silent. At least two small ones healed and fell off after a week, so there may have been some benefit.


As we do not have pain sensors in the brain, hopefully any cancers there, are murdered at the same time.

All info is for educational purposes only ... (and entertainment?)

[onawah]

It may be that I have just not diluted the DMSO enough, and that is why I experience the itching and burning.
Be sure to buy DMSO only in glass bottles, not in plastic as it can break down the plastic.

[onawah]

Apologies--I've corrected it now in the previous post, and what I meant to write is that you should be sure to buy DMSO only in glass bottles, and not in plastic since it is a solvent and can break down plastic, of which apparently we already have enough in our bodies now!

It may be that I have just not diluted the DMSO enough, and that is why I experience the itching and burning.
Be sure to buy DMSO only in glass bottles, not in plastic as it can break down the plastic.

[seekingtruth]

Thanks to OP and everyone who has contributed to this thread. You've convinced me to try it for a few things - tinnitus, macular degeneration, and something similar to a frozen shoulder.

I'm a little nervous about trying it for tinnitus as under no circumstances do I want to make it worse. Tinnitus is the worst, it robs you of quality of life. But seeing there is a book written exclusively on this topic gives me hope, I really need to dig into this more. (Anyone who has experience of DMSO and tinnitus, please do let me know how you got on.)

So I think I will test it on the other issues first, and go from there.

Thanks again, I will update in a few!

[silver birch]

I have not treated tinnitus, but my latest use of DMSO (with Hematoxylin) in rel high dosage, did not create any tinnitus at least.

Just a friendly reminder to anyone having a frozen shoulder fx, as I discovered many years ago,
do not take a lot of Aspirin as it cause temporary tinnitus. I told my doctor that I had tinnitus so I could not sleep, but he didn't ask what pain killer I took for the shoulder.

As our friend Wikipedia knows
"Large doses of salicylate, a metabolite of aspirin, cause temporary tinnitus (ringing in the ears) based on experiments in rats, as the action on arachidonic acid and NMDA receptors cascade.[219]" :cat:

[seekingtruth]

As our friend Wikipedia knows
"Large doses of salicylate, a metabolite of aspirin, cause temporary tinnitus (ringing in the ears) based on experiments in rats, as the action on arachidonic acid and NMDA receptors cascade.[219]" :cat:

Thanks for the heads up, did not know that.

[TrumanCash]

Getting Started with DMSO Webinars by Amanda Vollmer

Amanda Vollmer (ADV) is a Professional Holistic Health Practitioner (ADV) who holds a degree of Doctor of Naturopathic Medicine from the Canadian College of Naturopathic Medicine in Toronto and a Bachelor of Science in Agricultural Biotechnology.

Amanda has had a lot of information about DMSO and experience with it. RunningDeer has info on her book in a previous post here (https://projectavalon.net/forum4/showthread.php?74073-DMSO-Info&p=1639629&viewfull=1#post1639629). I watched her most recent paid webinar, DMSO Stroke Protocol.

Here some links to her free webinars on DMSO:

Learning About DMSO: A Beginner Class -- https://yummy.doctor/video-list/learning-about-dmso-a-beginner-class-with-amandha-vollmer-adv/

Understanding DMSO: Unlocking the Power of Terrain Healing -- https://yummy.doctor/video-list/understanding-dmso-unlocking-the-power-of-terrain-healing-with-amandha-vollmer-adv/

DMSO For Beauty: Supporting Skin, Hair & Youthfulness -- https://yummy.doctor/video-list/dmso-for-beauty-supporting-skin-hair-youthfulness/

Discover the Power of DMSO: Safe Use for Healing & Emergency Care -- https://yummy.doctor/video-list/discover-the-power-of-dmso-safe-use-for-healing-and-emergency-care/

DMSO and Respiratory Health: Cleansing & Terrain Support -- https://yummy.doctor/video-list/dmso-and-respiratory-health-cleansing-terrain-support/

DMSO Decoded: 45 Myths Busted with Facts & Clinical Experience -- https://yummy.doctor/video-list/dmso-decoded-45-myths-busted-with-facts-and-clinical-experience/

COMING SOON: DMSO and Natural Remedies for Pets – Join us November 15th! -- https://streamyard.com/watch/zbrxsi36Ddqy

Advance Your Knowledge with DMSO Masterclasses

For those ready to take their learning to the next level, the DMSO Masterclasses offer in-depth guidance, practical demonstrations, and advanced terrain-based protocols

These Masterclasses are exclusively available for purchase through a private, paid membership at Yummy.Doctor

Once a member purchases a specific Masterclass, access to that event and its recording becomes available through the corresponding private group inside the membership dashboard.

Each Masterclass is a separate product, which means access is limited to the exact session you’ve purchased — ensuring every participant has a personalized and focused learning experience.

Whether you’re seeking deeper insight into DMSO for pain, detoxification, skin healing, or neurological support, these sessions provide the detailed, natural healing applications you won’t find anywhere else.

Paid DMSO Masterclasses for Members:

1. DMSO for Chronic Pain, Arthritis & Mobility

2. DMSO Detox Protocols: Strategic Terrain Cleansing

3. DMSO for Skin, Scars & Wound Healing: Advanced Protocols

4. DMSO for Neurological Regeneration: Brain & Nerve Support

5. DMSO Stroke Protocol

Each session blends science, terrain wisdom, and practical instruction; empowering you to confidently bring DMSO into your natural healing routine.

Her website is https://yummy.doctor/

Holistic Living Videos with Amandha Vollmer which includes DMSO videos:
https://yummy.doctor/video/?mc_cid=a89f0e25cd

[Ravenlocke]

Hello Everyone,

I just got some DMSO from Amazon but it is 99.99 pharmaceutical grade (which needs to be diluted), so I also purchased this book on DMSO before I try using DMSO. I got the book because I wanted to know how to dilute it for safe use.

The book is easy to read from how DMSO came about, and used and how it can be used safely for many ailments. She explains how DMSO interacts with the body as well.

She also has a chapter on Pet use and formulas for dilutions for pets.

Healing with DMSO

the complete guide to safe and natural treatments for managing pain, inflammation, and other chronic ailments with dimethyl sulfoxide.

Author: Amandha Vollmer

Here is a link to the book on Amazon ,


https://www.amazon.com/dp/1646040023/ref=sspa_dk_detail_0?psc=1&pd_rd_i=1646040023&pd_rd_w=FfurY&content-id=amzn1.sym.953c7d66-4120-4d22-a777-f19dbfa69309&pf_rd_p=953c7d66-4120-4d22-a777-f19dbfa69309&pf_rd_r=1BSAA915WE991MYR2EZT&pd_rd_wg=FG690&pd_rd_r=f3f85b07-7d7d-4a2e-a8ba-4280124f0cbd&sp_csd=d2lkZ2V0TmFtZT1zcF9kZXRhaWwy


Also there are quite a few books on healing with DMSO but I picked the above book as a starting point.


Take care all.

[Ravenlocke]

Vigilant Fox 🦊

Jul 7
Replying to
@VigilantFox
and
@MidwesternDoc
DMSO concentrates in tumors, enhances chemotherapy, reduces doses, and lowers toxicity.

Studies show dramatic improvements—even in brain cancers!

Some doctors now pair it with ivermectin and fenbendazole for powerful synergy.

https://x.com/VigilantFox/status/1942267012023206348

1942267012023206348

[Ravenlocke]

Vigilant Fox 🦊

Nov 3
Replying to
@VigilantFox
and
@MidwesternDoc
DMSO gives people the ability to heal themselves—outside the control of the medical system.

That’s why the medical establishment buried it.

And that’s why it’s resurfacing now.

https://x.com/VigilantFox/status/1985433238249037916?s=20

1985433238249037916



[https://x.com/VigilantFox/status/1985426658376237245

1985426658376237245

[Ravenlocke]

Vigilant Fox 🦊

Jun 20
When DMSO was banned by the FDA, veterinarians didn’t have to stop using it.

That’s why so many Americans turned to horse-grade DMSO after the FDA crackdown.

It was their only way to access real healing—without a prescription.

Even today, some of the best DMSO is sold as “not for human use.”

Where have we heard this before?





One key caution: DMSO penetrates the skin deeply and can carry other chemicals with it.

You must always wash the area first—and avoid perfumes, pesticides, or metals near the application site.

That’s how powerful it is.

https://x.com/VigilantFox/status/1936157556054917436

1936157556054917436

[Ravenlocke]

Vigilant Fox 🦊

Jun 20
Thankfully, DMSO is legal again as a dietary supplement, thanks to the DSHEA Act.

You can buy it online—liquid, gel, or roller.

But the medical system still won’t touch it. No insurance. No mainstream doctors. No awareness.

Why? Because it would bankrupt the pain industry and bring about real healing.

But that’s fine. It’s time we finally take our health, wellbeing, and healing into our own hands. We know ourselves better than Big Pharma does.

https://x.com/VigilantFox/status/1936157884175598062

1936157884175598062

[Ravenlocke]

The 3 part video below is an interview DR Stanley Jacob did many years ago about DMSO on 60 minutes, and it also shows various people that healed themselves and also DR Stanley asking the Head of the FDA at that time if DMSO had killed anyone, you can listen to the answer that the head of the FDA responded to Dr Stanley Jacob


Part1

u0i7jARfKeI


Part2

icfh4x2vxbA

Part3

gvHNN2XbkqU

[Ravenlocke]

A Midwestern Doctor


Nov 7
This is a recent update from the man with terminal COPD who was able to cure it with nebulized DMSO. He is mostly recovered now and many others have also reported similar results asthma, severe COPD, and other "incurable" lung disease.🧵

https://x.com/MidwesternDoc/status/1986885372597395861

1986885372597395861

A Midwestern Doctor

Nov 7
This was the video
@RebeccaTig
sent me in July showing how Dan began reversing terminal COPD with DMSO and he regained hope for life plus a second video a few months later showing how much he continued to improve.

This story was quite profound and hence was seen by millions.

https://x.com/MidwesternDoc/status/1986885381648708059

1986885381648708059


Since posting this article, I have received dozens of stories like these of miraculous DMSO COPD recoveries



A Midwestern Doctor

Nov 7
DMSO also has a truly remarkable ability to save failing organs. One colleague recently shared it spared a scleroderma patient from a lung transplant and treated sarcoidosis in another, while another colleague successfully restored a lung succumbing to cystic fibrosis

https://x.com/MidwesternDoc/status/1986885384685453312

1986885384685453312


https://x.com/MidwesternDoc/status/1986885390007972279

1986885390007972279



https://x.com/MidwesternDoc/status/1987227033685139600

1987227033685139600

[thepainterdoug]

Some DMSO use and experience thus far. I bought pharma grade glass bottled DMSO. Amazon, delivered before I could log off. Along with that, some high quality castor oil in bottle

Mixed One to one in clean glass jar with glass dropper. Right now Im targeting my left forearm and back of hand for an unknown burning symptom that happens intermittently for the last 2 years.
And my right elbow, which wont straighten for about 10 years now, an ice hockey injury

1 week in. I have yet to have the burning under the skin. The elbow is no better or worse regarding the long standing injury.

The unexpected= the age spots on the back of my hand have disappeared in one weeks time. I also have a subtle sense of being in a little better health.

Im applying the mixture twice a day