Defeating biofilm forming bacteria in skin conditions [Archive]

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Bob

14th September 2016, 17:18

Bacteria can develop defences against our immune system.

Besides changing their internal gene codes (mutating) those which have been known to survive, can create a resistant coating called a "biofilm" which protects the bacteria from being recognized by the immune system.

Bacteria then can flourish and not be attacked.

Most often with any skin condition the invading bacteria can be a staph or strep species. Another form called pseudomonas can invade.

This is where it gets interesting -

Early on Rife noted in his studies of cancers, that there was a bacteria present, a fungus present and a virus present.. His logic was to break the pathogen cycle by attacking one or more of the invaders, thusly allowing the immune system to pick up the debris.

I looked into this many years ago (in the late 1980's) to see which methods were most effective in dealing with viruses, fungi and bacteria - ozone provided a really good solution for wide spectrum.

Traditionally, chlorine is used in some form of chlorine-oxygen molecule but it can have irritation and the adjustment level of chlorine-oxygen application is a bit of an art, getting the concentration just right..

When one is washing with a good soap - biofilms can be broken down, and the bacteria or fungus can be effectively neutralized. There are synergistic bacteria which live on the skin (and inside), which go after competing bacteria, and they themselves in the correct amounts won't become a problem (with a normal healthy immune system).

When things go wrong -

Out of balances upset cycles. Diet, stress, trauma, pollution and toxic overloads can upset balances.

Healthy bacteria may no longer be able to fight the dangerous bacteria. At that point some form of additional support becomes necessary.

I looked at Rife's logic and understanding at least some of the methods I came up with an experimental liquid salve for external application to specific spots on the skin that just don't seem to heal naturally (keeping such clean, washed, etc.)

The logic was to develop an all-in-one substance which is compatible with the skin to not burn it, or damage it, but to get past bacterial and fungal "biofilms" and to have components within to allow what is called "scaffolding" or a method for skin to re-knit itself, to build up without scar formations.

Also following Rife's logic, VIRUSES had to be addressed.. One of the nasty invaders opportunistic at that is the Herpes series of viruses (also noted in some human cancers)..

My choice of ingredients chosen then were to find common OVER-THE-COUNTER substances which could be used, blended together, and easily applied (dabbed with a cotton swab) onto an affected area.

Here are the ingredients that I found:

Tolnaftate Antifungal (Generic brand)
Terbinafine Antifungal (Generic brand)
Baby bottom High Zinc protectorant (zinc oxide content at least 40 percent used for "Diaper Rash" distributed by Wal-Mart)
Triple Antibiotic (Generic Brand - consisting of Polymyxin B sulfate, Bacitracin Zinc, Neomycin Sulfate, and optionally, Pramoxine HCL (a pain reliever)
Povidone Iodine Solution (Generic, not normal iodine/alcohol)
ChlorHexidine (Generic, obtainable from Walgreens, as a skin antiseptic cleanser)
Eucalyptus Essential Oil
Tea Tree Essential Oil

Mixing ratios (this can be scaled, but I prefer to mix up fresh batches when the smaller batch is used up)

1 squirt (a line length) of the two anti-fungals 1 inch long.
1 squirt (a line length) of the Diaper Rash Zinc Oxide, 1 inch long.
1/2 squirt (a line length) of the Triple Antibiotic, 1/2 inch long.

MIX COMPLETELY in a small container (like a miniature travel container that can hold 1 ounce).

It would be then a smooth paste, whitish in color, slightly translucent in appearance.

With an eye dropper, add in 3 drops of the Eucalyptus oil to the blended mixture. Mix well and completely.

With an eye dropper add in 2 drops of Tea Tree oil to the blended mixture. Mix well and completely.

With an eye dropper add in 10 drops of ChlorHexidine mixing completely while adding the drops, so that everything is uniform, and there are no lumps.

The aroma should be pretty smooth at this point.

Lastly add in the Povidone Iodine solution, drop-wise, one drop at a time, while stirring. The color of the mixture should start to change, from whitish to slightly light yellow as you add in the Povidone Iodine. This takes a bit of finesse to get it just right..

Add the Povidone Iodine dropwise while stirring/mixing well until the color no longer is light yellow but starts to change to a darker shade, like a dark mustard. Stop at that point, and continue to stir. The salve mixture at this point may be a bit liquidy, and the darker color may lighten up a bit. That is OK.

Keep it closed and out of any excessive heat (room temp is OK).

I use a Q-Tip dipped in and then apply to any skin issues, like twice a day, being sure that the skin is clean. I've noticed that after 3 days, any issue is cleared up.

The generics are EQUATE products.

Obviously if any allergic rash starts up discontinue application, and wash off, and if the condition doesn't improve seek additional medical care.

This is my research, it's not a recommendation to treat or cure. It is an interesting combination of substances, which attack bacteria and fungi which form biofilms, and the zinc is useful in attacking viruses.

I noticed that the Baby Bottom "Diaper Rash Relief" product contains cod liver oil, rich in Vitamin A.

I would think one could add in a drop or two of Vitamin E for the benifits of that.

I've used this mixture on lots of strange "spots" which certainly looked like they could turn into nasty issues, and found some amazing results.

References:

Biofilms - http://www.ncbi.nlm.nih.gov/pubmed/18703525
Herpes virus - http://www.webmd.com/vitamins-supplements/condition-1808-Herpes+simplex+virus+HSV.aspx?query=
Scaffolding (tissue) - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587658/

One additional note - this one is most often missed as it is a "matter of fact" note - Robert. O. Becker noted that when tissues are being regrown, (called healing) that a very slight voltage forms which causes the CELLS to migrate into and close up a wound.

Zinc, Silver oxide are useful to evoke a tissue potential, provided that they are properly applied exactly to the HOLE in the tissue (or absorbed in the SCAB). When the conductive ion (silver/zinc) is extended too FAR surrounding the scab, onto the healthy tissue, the potential gradient (that minute electrical current) doesn't form, and the cells can be killed instead of new cells forming to heal..

Overdoing it with too much conductive ions to induce that polarity then can be not a good thing..

Precisely applying such to the scab, or the trauma point then is key.

A little know fact about how tissue heals. (http://www.ncbi.nlm.nih.gov/pubmed/12016344)

Becker et-al were able to regrow finger tips using that technique, applying actual low voltage, electrical DC current in the proper polarity to "pull" the cells and to induce de-differentiation and reforming into proper cells (nerves bones, skin, muscle). Red blood cells have the method within to MORPH in other words, and STEM CELLS don't need to be used with that MORPHING technique..

Such has been some of my research from the 1980's - hope it helps understand biofilms better!

Images:

http://image.slidesharecdn.com/biofilm-150803160954-lva1-app6892/95/biofilm-details-treatment-specifics-3-638.jpg

https://dailymed.nlm.nih.gov/dailymed/archives/image.cfm?archiveid=49838&type=img&name=povidone-iodine-10-percent-solution-1.jpg

https://www.enasco.com/prod/images/products/39/AC118621l.jpg

https://i5.walmartimages.com/asr/fcf249de-dbcd-4204-b93a-61bbf6a665db_1.4af49ccb8a2511e991af1ead430a285f.jpeg

https://i5.walmartimages.com/asr/64796a8a-f359-423c-99b8-c0907804d217_1.b01965009f7c1e7509d5bc3efb4410ea.jpeg

https://www.drugs.com/otc/114048/EQUATE%20MAXIMUM%20STRENGTH%20%20DIAPER%20RASH%20RELIEF.jpg

http://cc.amazingcounters.com/counter.php?i=3190880&c=9572953

conk

14th September 2016, 17:40

Was just discussing this subject with my Functional M.D. yesterday. Our discussion was more particular to internal biofilms that make it difficult to eradicate Lyme, Epstein Barr, and other crafty little bugs that learn how to hide from antibiotics. I had been using an enzymatic approach to break down the film, then assault the pathogen with agents like Cat's Claw, Olive Leaf Extract, Oregano Oil, and many others. The doctor advised me to take care, that our beneficial bacteria also utilize biofilms to protect themselves. Got to do some more homework now.

Sunny-side-up

14th September 2016, 17:58

Great post Bob.

A natural liquid I came across many years ago is Kombucha.

It is a fantastic drink and lotion.

I used to make gallons of very strong versions.
I used to even have enough to bath in, makes you feel like your talked allover.

It can be washed over burns and forms a ultra fine layer to keep the air away from the burn.

A friend of mine was diagnosed with MRSA' he was a drinker and bather of my Kombucha, he was told one day by a very supprised Dr that his MRSA seems to have gone? :)

Anyways Bob you might try combining your brew with some.

Of course it's a non MSM so side effects? Brew your own to limit any.

TargeT

14th September 2016, 18:00

I usually just use coconut oil (from my understanding it's antiviral/antifungal/antibacterial) sometimes I toss in some colloidal silver... seems like it works on anything I've thrown it at.

avid

14th September 2016, 18:34

Colloidal silver seems to blast most stuff, sorry Bob, but you're way over most folks' heads/abilities/resources in your eloquent and scientific post above, which is almost certainly much better than me saying "colloidal silver". We can only manage basics in most circumstances.
However, please can folk who are able to utilise all Bob's recommendations give us feedback, as every cure is so important, and certainly the advice of an expert should be utilised to the full. ❤️
Can't access some products in other countries 🙁

Bob

14th September 2016, 19:00

Thanks to ALL who have posted related to what they use - much appreciated and a great set of additional ingredients to add. I would try the Kombucha mushroom as a powder (have to determine the concentration needed), and add an amount of the Coconut oil. The silver oxide/zinc combination as a dried powder would be needed as the colloidal silver liquid I think is much diluted. Again the exact amount to be determined.

For the conductive ion, my logic was to use the IODINE in the Povidone mixture, and because there is a type of adhering substance within the Povidone, that to me meant that it could act like a bit of a "scaffold" to help with giving direction for the new cells for healing. A SCAB is a type of scaffold you know, so scab formation is generally needed for a HOLE to heal correctly..

IF Biofilms form, they are what is called an insulator (a shield like plastic) which technically is a di-electric substance... so the HOLE is kept open and not properly healing (lesions in other words) thereby allowing the bacteria fungi and virus' perfect opportunity to flourish at the detriment of the body..

One of the co-researchers studying under Dr. Robert O. Becker came up with a silver-oxide impregnated bandage so that the antimicrobial properties of topical silver (silver applied in a band-aid) could be used to create that ELECTRICAL micro-current to help close up wounds. I found a proper dose of the conductive ion directly to the SCAB, and NOT the surrounding tissues was much better to create and KEEP that micro-voltage potential across the scab, for the new cells to grow without mutation.

That VOLTAGE potential in other words is essential during healthy tissue growth.. That opened up a LOT of understanding to Becker who realized that INTERFERING VOLTAGES from powerlines, or cellphones these days, or high powered transmitters CAN UPSET the normal healing. Becker lead the protests against powerline and transmitters messing with body health (such as cancers forming)..

SO that minute proper voltage, NOT being interfered with is part of the essential aspect of tissue healing...

One big issue is when diabetic leg lesions start to form to get such immediately being healed (with the proper cell voltage to close the wounds, and biofilms cleared).. Becker's co-researcher's found that silver-oxide bandages applied to the legs of the diabetic wounds would help provide the needed voltages..

avid

14th September 2016, 19:57

TargeT

14th September 2016, 20:09

Bob

14th September 2016, 20:09

Wow! Amazing explanations. Hard-wire where possible? We live in a microwave sick society, and it's being encouraged to unlock from tv aeriels, etc etc. Our homes will just buzz and frazzle us and our brains, no natural healing possible in such circumstances?

Becker brought to us understanding about the necessity for proper cellular formed micro-currents and voltages. He even showed how when chicken embryos were bathed in outside electrical currents while growing that they would be come distorted. Distortions these days sometimes we call them tumors, or cancerous growths..

My logic is based on the idea of a biopacer as far as whole body micro-energetic pacing. As the body is holographic energetically expressed (3D electric fields), just applying a single dimensional field to a 3D system only leads to partial regrowth, which is what Becker and others saw with their micro-current stimulation effects of severed limbs.. Such as with rats, they cut off limbs at the shoulder of the rat, and only the portion at the shoulder grew.. Point being there is a dielectric separation between the shoulder and each limb part, (elbow, hand, fingers) and each separation point in 3D blocks the signal of a microcurrent..

A finger-tip in their studies could regrow as there was no "dielectric" junction (the knuckle, the joints of the fingers) to get in the way of the micro-current. So I started my studies in full 3D holographic fields to understand shielding and potential restoration. (long story for another thread)..

The point being though, micro-currents are needed for a tissue wound to heal, and that the "dielectric" (the insulator) to the path of current for the cells blocks the proper pattern from allowing cells to migrate into. When a trachea for instance (windpipe) is re-grown, a mechanical scaffold is created in 3D and then cells from a tissue culture are allowed to grow onto the scaffold, all while maintaining the proper microcurrent charge to allow the cells to migrate in the right direction..

In the concept of the skin salve, the idea is to have a scaffolding material plus the method to create the proper micro-cellular charge JUST at the wound site (or injury site)..

When we have interference from outside energies from powerlines, transmitters, those microcellular currents are deviated, and any odd patterns appearing within those cellular currents then can give rise to distortions in the body/organ pattern.. (cancers, tumors, deformities).

In the thread a biochemical "body electric" concept is looked at.

TargeT

14th September 2016, 20:12

Bob

14th September 2016, 20:13

Bob

14th September 2016, 20:20

so... are reptiles/amphibians more like super conductors for the microelectric currents? they run "cooler" over all and can regrow limbs (in general) or does that phenomenon occur due to something else in this theory?

WOW - what a concept - never thought of looking at it in that way, why reptiles and amphibians have such good abilities to limb re-grown... I always thought it had to do with a different neural circuit, a different electrical pattern which was more consistent across their tissues..

Such amazing doorways would be able to be opened understanding better these micro-cellular currents !

fourty-two

14th September 2016, 20:29

Bob

14th September 2016, 20:51

Great post, Bob. I have found - that on my body- Betadine (name Brand) works slightly better than generic povidone iodine.
Do you think applying a smear of DMSO on the skin before the mixture would be benificial?

An excellent observation and thoughtful question !

I chose the Povidone because of the glue-like material within, which forms a simple scaffold. I bet one could use the actual scaffolding molecules that are used for instance for helping with wounds on Horses (TargeT do you know of that substance being used to facilitate wound closure on them?).

Here is the technical history of Povidone -

Povidone-iodine (PVP-I), brand name Wokadine, Pyodine, and Betadine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine.

It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. It is less toxic than tincture of iodine (iodine alcohol mixture).

The substance called Poly-Vinyl-Pyrro-lidone ( separated out the word so it could be pronounced easier) acts as the scaffold, or that which holds the structure in a type of membrane..

If one looks at tissues for instance in which the top layer of skin is torn off, rapidly before the blood covers it, a thin membrane starts to form the basis for the first bottom layer of the scaffold.

The body then basically has the necessary scaffold mechanism for the cells to move onto from the red blood cells.. Then the red blood cells morph - amazing really, that because the whole body's electrical pattern exists in 3D form (an electrical hologram so to speak) in the DNA, when triggered the cell becomes what is needed to match the appropriate cell at the body location where they are exposed.. (Of course that opens up amazing thoughts about how far can body morphing go.. hmmm besides just reconstructive healing..

On the DMSO question - I've experimented with it and found it can cause too deep a penetration. I was looking at the substances within the Triple Antibiotic, and the Baby Bottom Rash as the carrier into the tissues to not get in TOO deeply.. I really like TargeT's idea to add some Coconut oil..

== update ==

I think I will update the thought here on the DMSO pre-addition to the skin. It's used to get substances IN rapidly - whether or not it is rapid penetration into the capillaries which is the mechanism in tissues, or muscles I am not exactly sure..

I suppose if one has a deep penetrating issue where biofim bacteria and fungi have reached, it may be a life saver !! But experience says it can convey deeply any of those substances on the skin. It MAY be an excellent bio-film destroyer in itself. I think such warrants more use on testing cell cultures, and bacteria/fungal petri-dish like "PLATES" to see exactly what it does to those things..

Here is some background on DMSO

Dimethyl sulfoxide (DMSO) is an organo-sulfur compound with the formula (CH3)2SO. - That is METHANE (from the wood pulp that it is extracted from, plus Sulfur plus Oxygen)..

This colorless liquid is an important polar aprotic solvent that dissolves both polar and nonpolar compounds and is miscible in a wide range of organic solvents as well as water.

It has a relatively high melting point.

DMSO has the unusual property that many individuals perceive a garlic-like taste in the mouth after contact with the skin.

DMSO is used to alter DNA during certain manipulations. SO the potential to allow bacteria and fungi to have ACCESS to one's DNA may not be a good idea.. For that reason.. It is frequently compounded with antifungal medications, enabling them to penetrate not just skin but also toenails and fingernails.

Double edges sword? I don't know on the DMSO - that's some of the data on it.

Sunny-side-up

15th September 2016, 13:07

A very inportant post, thx Bob

Thank you for reminding me that we are all: Bio, Electal, chemical bodies, and not forgeting the other dimensional, spiritual aspects to our exsistance as material beings.

I like your minds view and attempts to create something great in the pandoras box we call reality.

So on a side note you started me thinking of Orgon energy, the so called 'Life-Force-Energy' of this universe.

Now organite is a combination of materials and effects.
Quatz-crystal held under presure within a solidified resin (Not sure about the resin aspect of the organite devices)
I believe the Iron/metal particals are used to deflect and or absorb negative energies, not directly needed to generate Orgon (might be woung there)

So in relation to your OP, you started me wondering if an advanced Orgonite could be made, advanced as in a liquid soloution or mabe even micro versions as powder?
A liquid form that could be spred over a wond (Included in a treament)
Instead of the resin causing a presure on the quartz (Which in the liquide would be micro particals of quartz etc) maybe there could be some kind of chemical agent added to cause induce a presure on the quatz?
I like the idea, if safe for human consumption, of a drinkable Organ producing elixia :)
Wild thoughts from some one who has no real clue to what I'm talking about hehe, but thoughts induced by your clued up mind there Bob :sun:

Bob

15th September 2016, 15:58

A very inportant post, thx Bob

Thank you for reminding me that we are all: Bio, Electal, chemical bodies, and not forgeting the other dimensional, spiritual aspects to our exsistance as material beings.

[..]

Hia - keeping constant with the OP, and expanding along the lines of the electrical nature, Orgonne would fall into reaching within that physical structure. In the actual making of Orgonne the structure resembles layering, like an onion, of layers, each layer alternating, conductor metal, electric insulator, conductor metal, electric insulator. The spacing between the layers sets up the WAVELENGTH of the electromagnetics which get trapped or stored. The wavelengths of Reich's orgonne layering comes out into the far infra-red through near infra-red range,

Atoms can very easily vibrate within that range, and they have resonances with far-infra-red and near infra-red wavelengths. So one can say, an orgonne system can charge up certain atoms (and molecules which are groups of atoms).

I would think a more "molecularly" compatible substance consisting of let's say a "holographic-metalized" "glucose" (sugar) would be biologically compatible. In the 1990's I developed a method of creating such layers, atom by atom, with vibratory patterns lain within.. I used sugar, making such a type of "rock candy". It had all the orgonne component's effects without a potential for metals toxicity. Metals toxicity can be quite a problem, and folks have tried making "residual metal" drinks before, with disasterous consequences. (Their processes were what they were calling, "plasmatic" instead of defining it as "orgonne-ic", but the issue being, toxic metals are not good for one. )

The holographic version (what would be called an electronic field representation of something, but not a physical substance) of "gold" was used with a compatible sugar. The sugar concentrate was grown in the presence of the "holographic field". So within the crystal growth, each sugar crystal would have "virtual components of gold".. And that matrix grew to quite some size, and the "feeling" coming off such reported by testers was 10,000 X greater than any physically created orgonne assembly..

I looked at then if the other important molecules and atoms could be layered in as well, and for a few years (1991-1995) did some betatesting with our group. We abandoned the research after the data was obtained - I suppose someday we'll get back into it. My goal at that time was what could we create such as "virtual nutrients", or a way to synthetically create food without having to have to kill plants, or directly using sun energy (as electricity), and "holographic field structure" as the patterns - growing "organic crystals" without needing the "plant".. So no death involved, but pure life cycle energy was the result.. Kinda advanced for this society, maybe lightyears past the mindset of shortage manipulation, "economy", and control..

Bob

15th September 2016, 20:50

Next couple posts, I will bring up the characteristics of the various substances listed in the OP.

First of all, the idea of TISSUE SCAFFOLDING is what I want to look at.

An EAR (external structure we recognize as an ear) has a shape. If one took a group of let's say human cells and put them in a Petri-Dish and "grew them" without any "scaffold" there would be a mass of cells, and it certainly would not show the shape of the external ear. To grow the ear some structure has to be created such as the "cartilage" of the "ear" that has the shape. The cells then placed onto a properly "micro-current-charged" cartilage will then over time, grow in the shape of an ear..

Polyvinylpyrrolidone (povidone) within the Povidone Iodine, is a polymer which is capable of forming large scaffolds. Here is what it looks like. I used a 3D (cross-eyed viewable representation) image. Those who do soft-focus, or cross eyed viewing can see the depth in the virtual "center" image in virtual 3D (without glasses).

http://chanlo.com/images/poly-1.jpg

Onto and within this scaffold the iodine (the metallic ion) plus the other substances form a 3D geometry allowing the cells (in the wound or infection, or injury) to have some protection for outside additional contamination, as well as forming the underside of a "polymer-like scab", similar to a natural scab that the body would create from blood cells, plasma "fibrinogen" and T-Cells.

This "scaffold" molecule is water soluble, so it can easily be washed away if desired, and capable of dealing with bodily fluids allow such to integrate into the polymer scaffold.

Some background on the polymer. During World War 2, when there was a shortage of even Whole Blood for transfusions and Blood Plasma (the clear stuff without the red blood cells), this polymer was added to what plasma they had to "extend" the usefulness.

One could not just add water to extend plasma, as the missing "fibrinogen" (the body's natural scaffolding) had to be somehow replaced. Povidone, the scaffolding polymer came to the rescue and amounted to saving countless lives with blood plasma extended with this safe polymer.

Bob

16th September 2016, 00:01

It is interesting the Chlor-Hexi-Dine (chlorhexidine) also consists of scaffold-like molecule - here is an image of how the molecule is lain out:

https://upload.wikimedia.org/wikipedia/commons/3/3e/Chlorhexidine_3D_ball.png

It is listed as an antiseptic substance with bactericidal characteristics. It is used often in pre-operative surgery to clean skin. Studies have shown that bacteria can NOT develop resistance to this substance.

It is also used in certain cosmetics (also as an additive to creams, toothpaste, deodorants, and antiperspirants). Nepal is the first country in the world to use chlorhexidine to treat the umbilical cord of newborn babies.

For use in animals, chlorhexidine is used as a topical disinfectant of wounds. It is also more beneficial to wound healing than using saline solutions alone.

Chlorhexidine is active against Gram-positive and Gram-negative organisms, facultative anaerobes, aerobes, and yeasts.

It is particularly effective against Gram-positive bacteria (in concentrations ≥ 1 µg/l). Significantly higher concentrations (10 to more than 73 μg/ml) are required for Gram-negative bacteria and fungi.

Chlorhexidine plus gluconic acid creates a substance called "ChlorHexidine Gluconate" which has been used to stop and prevent gingivitis and facilitate healthy gum regrowth.

It is commonly used to manage skin infections in dogs. In addition to this, it is an active ingredient in teat disinfectant products used within the dairy farming industry.

It is considered safe, although it is not recommended to be swallowed.

Bob

16th September 2016, 00:19

Terbinafine is prescribed to treat fungal infections in adults.

It is commonly prescribed for fungal nail infections and is sometimes prescribed for fungal skin infections. It works by killing the fungus causing the infection.

Terbinafine is available in a very dilute CREME or as oral (Rx) tablets for systemic fungal treatment.

We are only going to look at the topical (skin use) which has a very low level of the active ingredient. The topical version is used to treat a variety of fungal skin infections such as ringworm, athlete's foot, and jock itch. This medication is also used to treat a skin condition known as pityriasis (tinea versicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs. It is available Over-The-Counter (OTC).

Terbinafine is increasingly used in combination with other antifungal agents to treat resistant fungal infections. We are using the synergistic effect of adding Tolnaftate (the other antifungal) to the mixture.

Walgreens makes a Terbinafine Hydrochloride Cream at a 1% strength. The tube is about 0.53oz. Do not get this in the eyes or mouth.

User comments of the Topical 1% Terbinafine cream:

Just brought this a few days ago and it stopped the itchy, red and moisture of the jock itch. This stuff is great. After just one day things where better, after 2 days it was almost gone, and on the third day is was gone. I keep using the cream for the rest of the week to be sure it was dead and buried. I will be keeping this in the house from now on.

It has shown me that is a very good antifungal.

Bob

16th September 2016, 00:33

Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.

It is OTC and may be sold without medical prescription in most jurisdictions. It is supplied as a cream, powder, spray, and liquid aerosol. Tolnaftate is used to treat fungal conditions such as jock itch, athlete's foot and ringworm.

Tolnaftate has been found to be generally slightly less effective than azoles when used to treat tinea pedis (athlete's foot).

It is useful when dealing with ringworm, especially when passed from pets to humans. Did you catch that? One can pick up an opportunistic fungal infection from a cat scratch, or a dog scratch from their nails, or brushing an infected area with a hand or arm, or hanging out where your cat or dog sleeps (when you are not looking - they just love your couch seat !)

One of the leading "trade named" versions of tolnaftate is called Tinactin(r). (Much more expensive than the generic tolnaftate). This is pretty much the generic treatment found when folks end up with some type of fungal infection. It has had hundreds of millions of successful uses. It should not be taken internally, and should be kept away from the eyes. When there is a typical body fungus that tolnaftate can't handle, usually terbinafine will, and visa versa. It has been used to treat yeast infections of the skin.

Bob

16th September 2016, 00:59

Getting into the ingredients of the "Triple Antibiotic" skin cream.

Polymyxin B is an antibiotic primarily used for resistant Gram-negative infections. It's bactericidal action works against almost all Gram-negative bacilli except the Proteus and Neisseria genera. It has little to no effect on gram-positive bacteria. Polymyxin B has been used to treat urinary tract infections and meningitis caused by Pseudomonas aeruginosa and Haemophilus influenzae.

Bacitracin is primarily used as a topical preparation - it is not to be used internally. It is typically used for the prevention of wound infections. Bacitracin considered as a broad spectrum antibiotic. It targets both Gram-positive and Gram-negative bacteria, especially those that cause skin infections. The following represents susceptibility data for a few medically significant microorganisms: Staphylococcus aureus – ≤0.03 μg/mL – 700 μg/mL, Staphylococcus epidermidis – 0.25 μg/mL – >16 μg/mL, and Streptococcus pyogenes – 0.5 μg/mL – >16 μg/mL

Neomycin is an aminoglycoside antibiotic found in many topical medications such as creams, ointments, and eyedrops. The discovery of neomycin dates back to 1949. It was discovered in the lab of Selman Waksman. Neomycin belongs to aminoglycoside class of antibiotics that contain two or more aminosugars connected by glycosidic bonds. Neomycin has good activity against Gram-positive and Gram-negative bacteria. It is especially good at treating Enterobacter cloacae: >16 μg/ml, Escherichia coli: 1 μg/ml, and Proteus vulgaris: 0.25 μg/ml.

The combination of those three are the typical ingredients used in the over-the-counter product called "triple antibiotic".

A 4th component is often used, as a very weak local pain killer called: Pramoxine HCL. Pramoxine is used to temporarily relieve itching and pain caused by minor skin irritation such as minor burns/cuts/scrapes, sunburn, eczema, insect bites, cold sores, or rashes from poison ivy, poison oak, or poison sumac. The Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in humans.

I prefer to use the "triple antibiotic" with the Pramoxine component because some skin issues do have itching and pain associated. I've found this product available over the counter at WalMart stores.

http://cc.amazingcounters.com/counter.php?i=3190880&c=9572953

Pam

16th September 2016, 03:11

Bob

16th September 2016, 04:50

This is a really interesting thread. In my experience as a nurse biofilm was very problematic when it formed on catheters internally, those used to access the bloodstream or to remove urine.

This can pose a most difficult situation allowing for chronic infection in catheters that are meant to stay in place for a longer time.

Much of the time even the strongest of antibiotics would not be able to penetrate the slimy biofilm coating.

Enzymes that were injected and left within the catheter could be very effective in breaking down the biofilm.

I have also seen success with large amounts of enzymes have been taken for internal biofilm that grows in the urinary bladder. In my experience biofilm is more problematic internally then it would be externally.

Hia - I added some white space in-between the lines for clarity. I certainly follow that logic clearly, e.coli being notorious for urinary tract (catheter induced) infections.. (UTI's)

Here is one particular ORAL biofilm method study, of all things CONCENTRATED Cranberry Juice:

Title: Cranberry juice consumption may reduce biofilms on uroepithelial cells: pilot study in spinal cord injured patients.

Reid G1, Hsiehl J, Potter P, Mighton J, Lam D, Warren D, Stephenson J.
Author information

Abstract
STUDY DESIGN:
A pilot study of 15 spinal cord injured patients.

OBJECTIVE:
To determine whether alteration of fluid intake and use of cranberry juice altered the bacterial biofilm load in the bladder.

SETTING:
London, Ontario, Canada.

METHODS:
Urine samples were collected on day 0 (start of study), on day 7 following each patient taking one glass of water three times daily in addition to normal diet, and on day 15 following each patient taking one glass of cranberry juice thrice daily. One urine sample was sent for culture and a second processed to harvest, examine by light microscopy and Gram stain non-squamous uroepithelial cells to generate bacterial adhesion per 50 cells data.

RESULTS:
The results showed that cranberry juice intake significantly reduced the biofilm load compared to baseline (P=0.013). This was due to a reduction in adhesion of Gram negative (P=0.054) and Gram positive (P=0.022) bacteria to cells. Water intake did not significantly reduce the bacterial adhesion or biofilm presence.

CONCLUSION:
The findings provide evidence in support of further, larger clinical trials into the use of functional foods, particularly cranberry juice, to reduce the risk of UTI in a patient population highly susceptible to morbidity and mortality associated with drug resistant uropathogens.

Reference Source: http://www.ncbi.nlm.nih.gov/pubmed/11224011

Bob

22nd September 2016, 22:55

I've found for really stubborn skin issues that increasing the amount of ChlorHexidine by 3x works really well. Stubborn issues would be a redness around the scab that doesn't start to change to a more brownish color instead of fiery reddish.. Apparently the ChlorHexidine has a way of penetrating the surrounding area where the biofilm may have build up (thinking out loud) and removes such allowing the other substances to defeat the virus, bacteria and/or fungi.

I've also watched this work on small "hives" like spots that for some reason erupt for no apparent reason. I suspect a skin pore is being attacked, which then a rapid immune response kicks in, but the immune response is not adequate to go after what embedded itself in the pore. With early acne issues, sulfur and resorcinol was used (see: https://www.drugs.com/cons/resorcinol-and-sulfur-topical.html). I can't say I have been a fan of either of those two, but they have been staples for many years for youth afflicted by terrible skin acne. Resorcinol/sulfur terribly peels the skin while it is killing off the staph skin infection. Very harsh.

Getting some tissue/skin penetration without too much spread, (cautious use of Di-Methyl Sulfoxide, DMSO?) seems to be a good idea, but it seems like too much would not be good.