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Thread: How to check if Charlie Ward's "flu vaccine" claims are true or false

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    Scotland Avalon Member
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    Default How to check if Charlie Ward's "flu vaccine" claims are true or false

    #dyor It's no use following Youtube rumours on a "faith" or "dismissal" basis.

    1. Go to the OECD coverage statistics for over-65's and a reasonable sample of countries. Get a spreadsheet and enter the coverage rates in 1 column

    2. Go to the Covid-19 realtime statistics and cross-reference each country's "Deaths/1M pop" figure. This is the most reliable since deaths per case is all over the place due to wide differences in testing. (Tip: click on the column header for that column to sort in descending order. That brings all the "problem" countries to the top. Notice the significant difference between the top 10-15 and the rest). Populate column 2 of your spreadsheet with these figures

    3. You need to distinctly account for the adjuvanted/non-adjuvanted status. It is a distinct medicating component that's added to the vaccine in order to generate a more powerful immune response. The reason this is important is because:
    • it's only given to over-65's and certain immuno-comprimised groups (the OECD data above applies to over-65's, so compatible)
    • its use is delineated by health jurisdiction. Some health ministries have an over-65 adjuvanted policy, some don't (so compatible with the death rate data which is also grouped by country)
    • while the vaccine changes from year to year, the adjuvant doesn't and recipients are re-medicated with it each year. The adjuvant is squaline (shark oil) in an oil-in-water emulsion which is stabilised with an additive called Polysorbate 80
    4. In column 3 of your spreadsheet, identify the health juristictions which have non-adjuvanted vaccination policies for over-65 and immunocompromised. Set their coverage rates to zero while copying the other coverage rates across from column 1.

    You'll end up with 2 graphs: 1 with death rate against influenza vaccine coverage in general and 1 against adjuvant coverage. Step 3 is slightly non-trivial and requires a bit of work. Even at that, definitive figures are quite opaque. See below.

    ****** SIDE NOTE: *****

    This is an extremely important public health consciousness exercise whatever side of the "vaccine debate" people find themselves on since the public are the consumers of these medication products yet the statistical data is quite opaque beyond generalised coverage rates.

    Everyone must participate. If people are not numerate then get someone who is to assist and help each other validate information resources. Otherwise we are sitting on our hands with our thumbs in our mouths listening to random Youtubers mouth off. The work is supposed to be done by an activity called "pharma covigilance" but if this institutionalised process ever comes up with "uncomfortable results" it's unlikely that they'd be instantly made available. For example, having spoken to healthcare professionals in the UK I'm fairly certain that Covid-19 deaths are not being cross referenced to medication history and primary care records, at least not officially that I'm aware of and certainly not openly. Also, there are simply a myriad of conflicts of interests involved and the more the public are familiar with what they are consuming, the less they'll be manipulable by scare stories (in either direction). I'm sorry but there really is no other way than to do the research YOURSELF or in well informed groups in order to arrive at a more informed perspective than is provided by random Youtube comments, albeit assisted by professionals that you trust if necessary. (Though this being a simple statistical exercise should not require anything other than counting skills).

    Regarding step 3 above, the OECD statistics make no distinction between adjuvanted and non-adjuvanted coverage even though the vaccine and adjuvant are distinct medications. (So distinct in fact that the adjuvant can be contracted for manufacture even when the vaccine doesn't yet exist).

    To determine this information it's necessary to go to each country's health ministry websites or other indirect sources. In the abscence of officially stated policy, some guesswork may be required via recourse to indirect resources such as news items covering vaccine contracts placed by health authorities with vaccine manufacturers or teaching resources created by local healthcare professionals. (More publicly available & accurate information on this would be helpful in terms of supporting confidence in vaccine performance).

    3 general categories emerge with specific regard to adjuvant use:
    A: Current, unambiguous adopters (Health juristictions that unambiguously recommend the adjuvanted version to over-65's, care homes & immuno-compromised)

    B: Historical adopters (May be currently licensed or unlicensed, may have had a previous swine flu - Pandemrix- campaign)

    C: Non-adopters

    Here's some links to start you off. Don't be lazy now

    Europe: Background to Adjuvanted Influenza Vaccine Licensing

    The adjuvanted flu vaccine has a history of use in most European countries, however is only licensed in some of them at the present time according to EU licensing tables.

    In general, the adjuvanted vaccine is licensed for over 65’s in:

    Some European Union countries (Spain + Italy have the longest continuous use reportedly) + UK
    United States
    Canada

    See:
    https://www.arznei-telegramm.de/html...009075_01.html

    https://www.ecdc.europa.eu/en/season...luenza-vaccine

    Country by country table:
    https://www.ecdc.europa.eu/en/public...-201920-season

    And background to the MF59 adverse event in Italy and subsequent suspension by some EU countries:
    https://www.tandfonline.com/doi/pdf/...5.2017.1420448

    USA: Background:

    Quadrivalent version trials carried out in Boston and North Carolina (Dukes University Medical Centre)
    https://clinicaltrials.gov/ct2/show/NCT03183908

    Chile

    Statistics on types of vaccine, composition (with particular regard to adjuvants) and coverage for Chile are not very easy to acquire. However this document produced by the Chilean ministry of health (Ministereo de Salud) does specifically state the Vaccine brands being deployed for the year 2017.

    https://www.minsal.cl/wp-content/upl...umococcica.pdf


    The Spanish association of Vaccinology has a useful table with which to cross-reference brand names in the Hispanic world to vaccine content, in particular whether or not they are adjuvanted.

    https://www.vacunas.org/vacunacion-7/

    New Zealand
    This document has been published by the New Zealand Immunisation Advisory Centre:
    https://www.influenza.org.nz/2020-fu...uenza-vaccines

    It indicates the vaccine brands being deployed for the 2020 flu season.

    https://immunisationhandbook.health....s/afluria-quad
    https://immunisationhandbook.health....influvac-tetra

    Israel
    The Health Ministry of Israel does not appear to publish specific guidance as to vaccine brand or type recommendations on its publicly accessible pages. However one of the largest of its state-mandated health organisations (Clalit) appears to use a quadrivalent nasal-spray vaccine.

    https://www.clalit.co.il/he/medical/....aspx?idd=8007

    https://web.archive.org/web/20180119...cinations.html

    https://www.health.gov.il/English/To...n_Elderly.aspx

    https://www.businesswire.com/news/ho...-2018-2019-Flu

    Belgium

    https://www.ema.europa.eu/en/news/no...d-deaths-italy
    
Note also that the Belgian government’s scientific committee for coronavirus has stated that Belgian death rates “should be halved” to obtain a comparable statistic with other countries due to their reporting protocol.

    https://www.politico.eu/article/why-...-toll-so-high/
    https://www.bostonglobe.com/2020/04/...ropes-capital/

    See also:
    https://archpublichealth.biomedcentr...-7367-68-3-109

    https://www.lemonde.fr/planete/artic...5770_3244.html
    https://medicalxpress.com/news/2014-...u-vaccine.html
    https://www.vaccination-info.be/maladie/grippe/
    https://www.gsk.com/en-gb/media/pres...e-development/

    Singapore

    https://www.parkwayshenton.com/healt...get-vaccinated

    http://activeage.co/new-four-strain-...-in-singapore/

    https://www.raffleshealth.com/flu-va...sultation.html

    https://www.moh.gov.sg/news-highligh...r-the-schedule

    Vaccine coverage in Singapore:
    https://www.todayonline.com/singapor...ne-jabs-adults

    https://trialsjournal.biomedcentral....808-8#ref-CR18


    The Netherlands

    https://www.rivm.nl/bibliotheek/rapporten/2019-0002.pdf
    
Also:
    https://www.rivm.nl/griep-griepprik/...en/griepvaccin

    Brazil
    Historically there were substantial emergency vaccination programs deployed in 2015 and 2016 in response to the Zika and H1N1 (swine flu) viruses.

    https://pubmed.ncbi.nlm.nih.gov/22609010/
    http://rsaude.com.br/florianopolis/m...nza-2017/12355
    https://www.bbc.co.uk/news/world-latin-america-36145181

    https://saude.abril.com.br/medicina/...meca-em-abril/

    Iceland

    https://www.landlaeknir.is/servlet/f...0s%C3%B6gu.pdf

    https://www.heilsugaeslan.is/um-hh/f...ri-influensu-/

    https://www.landlaeknir.is/gaedi-og-...gegn-influensu

    https://www.serlyfjaskra.is/FileRepo...e%C3%B0ill.pdf

    Australia:

    https://www.abc.net.au/news/2018-02-...o-know/9461766
    https://www.ebs.tga.gov.au/ebs/picmi...02006111016933
    https://www.eurosurveillance.org/con...#html_fulltext
    https://www.health.gov.au/health-top...tion-service-0
    https://theconversation.com/heres-wh...s-so-bad-86605

    Czech Republic

    https://www.ockovacicentrum.cz/cz/vaxigrip-tetra

    https://vakciny.avenier.cz/cz/chripkova-sezona-20192020

    Germany
    https://www.pei.de/DE/arzneimittel/i...enza-node.html

    Portugal

    https://www.dgs.pt/directrizes-da-dg...-14102019.aspx

    Japan

    https://www.nibiohn.go.jp/CVAR/adjuvant.html

    Sweden

    https://www.snih.org/tales-of-the-pa...psy-in-sweden/

    https://www.janusinfo.se/nyheter/nyh...2b301d37a.html

    https://medikament.se/l%C3%A4kemedel...019-injektion-

    https://www.folkhalsomyndigheten.se/...pper-15100.pdf

    Northern Ireland

    https://www.publichealth.hscni.net/n...al-flu-vaccine

    Republic of Ireland

    https://www.hse.ie/eng/health/immuni.../chapter11.pdf

    France

    https://pubmed.ncbi.nlm.nih.gov/15599987/

    https://www.has-sante.fr/upload/docs...-46-16_310.pdf

    Korea

    https://www.ncbi.nlm.nih.gov/pmc/art...MC6312896/#B15

    See:
    https://koreauniv.pure.elsevier.com/...for-the-elderl

    https://synapse.koreamed.org/DOIx.ph....2017.49.4.247

    Norway

    https://www.seqirus.com/news/fluad-tetra-chmp

    Currently available flu vaccine brands in Norway:
    https://vaksinebestilling.fhi.no/pro...luensavaksiner

    Estonia
    https://www.virtuaalkliinik.ee/uudis...gripivaktsiini

    Slovenia

    https://www.adm.si/Nasveti?n/9HND3SWV


    Turkey

    http://www.medikalteknik.com.tr/gskd...ortluk-koruma/
    https://istanbulalerjimerkezi.com.tr/grip-asisi/

    Hungary

    https://www.webbeteg.hu/gyogyszerker...tegtajekoztato

    Finland

    https://perusterveys.fi/influenssarokotus/
    https://thl.fi/fi/web/infektiotaudit...fluenssarokote
    https://www.keski-uudenmaansote.fi/a...ssarokotukset/

    Denmark

    https://www.ssi.dk/produkter-og-ydel...tion-2019-2020
    http://xnet.dkma.dk/indlaegsseddel/P...=16307&lang=da

    http://xnet.dkma.dk/indlaegsseddel/P...id=926&lang=da

    8. Brand Names

    https://www.drugs.com/ppa/influenza-...activated.html
    https://vk.ovg.ox.ac.uk/vk/vaccine-ingredients#MF59
    Last edited by indigopete; 27th July 2020 at 13:33.

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    Default Re: How to check if Charlie Ward's "flu vaccine" claims are true or false

    Part 2 - Technical Stuff

    Here is some background technical info for anyone that's interested. Much of it is general microbiology background and not necessarily directly related to vaccines. Some of it covers autoimmunological phenomena that describe the type of "cytokin storm" event that occurs in Covid-19 deaths. (i.e. patients that ostensibly die from Covid-19 rather than with it).

    The UK.GOV Public Health England website describes 2 general types of vaccine: Quadravalent influenza vaccines and adjuvanted trivalent vaccines.

    https://www.gov.uk/government/public...n-primary-care
    https://www.cdc.gov/flu/prevent/adjuvant.htm

    There are generally 2 types of adjuvant in general use according to commonly available resources - aluminium salts (the “traditional one) and the more currently used emulsified squaline (shark oil) which dates back to 1997 which is used in proprietary owned, patented adjuvants. The earliest use appears to have been in Italy, then Spain. It had a “hiccup” around 2012 and some countries suspended its use, but later research concluded that the adjuvant was not the cause of the adverse events cited and use was resumed by some countries.

    In 2016 it became licensed in the United States (only for over 65’s) and has been in use in the UK since around 2017.

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685699/

    https://www.cdc.gov/flu/prevent/adjuvant.htm

    Description of Adjuvanted Influenza Vaccines including comprehensive table of vaccine types, brand names and adjuvant:
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861793/

    Covid-19 Lethal Symptoms Description
    https://science.sciencemag.org/conte...b8925.full.pdf
    https://www.sciencedirect.com/scienc...59610120300927

    Description of the “oil in water emulsion” approach and overview of all the current flu vaccine adjuvants:
    https://www.medscape.com/viewarticle/589163_2
    https://www.sciencedirect.com/scienc...43661815001711

    Detailed paper on mechanism:
    https://synapse.koreamed.org/Synapse.../ic-45-159.pdf

    Policy documents on influenza vaccination:
    https://assets.publishing.service.go...April_2019.pdf

    https://www.england.nhs.uk/wp-conten...IV-vaccine.pdf

    Cell biology background papers:
    https://www.nature.com/articles/s41577-020-0304-7
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149857/
    https://www.cell.com/immunity/fullte...613(09)00065-X

    Fighting COVID-19 exhausts T cells
    https://cvi.asm.org/content/21/7/989

    Other studies on adjuvanted vs non-adjuvanted vaccine & immunogenecity:
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724206/
    https://www.cell.com/immunity/fullte...613(10)00367-5
    https://cancerimmunolres.aacrjournal...ontent/1/3/145
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780956/
    https://pubmed.ncbi.nlm.nih.gov/28925801/
    https://pubmed.ncbi.nlm.nih.gov/18294741/

    History of the “Adjuvant Concept”
    https://www.tandfonline.com/doi/full...5.2016.1225635

    Guardian article:
    https://www.theguardian.com/society/...ve-flu-vaccine

    WHO page on Squalene-Based adjuvants:
    https://www.who.int/vaccine_safety/c...nd_answers/en/

    History of branded adjuvant
    https://pubmed.ncbi.nlm.nih.gov/23256736/

    Brand names:
    https://adisinsight.springer.com/drugs/800013987

    https://markets.businessinsider.com/...ing-1027839984

    European countries where adjuvanted influenza vaccines are approved:
    https://www.ema.europa.eu/en/documen.../201903_en.pdf

    Adjuvanted flu vaccine approved in US for “seniors”:
    https://www.webmd.com/cold-and-flu/n...mmune-response

    Wikipedia vaccine brands:
    https://en.wikipedia.org/wiki/Season...vaccine_brands

    Hispanic world brands:
    https://www.vacunas.org/vacunacion-7/

    This document contains some detailed technical information on the immunogenicity of the branded adjuvant contained in the influenza vaccine:
    https://www.canada.ca/en/public-heal...-2020.html#IV1

    Adjuvant Concerns at the time of H1N1:
    https://web.archive.org/web/20140703...f-destruction/

    Answered:
    http://www.nejm.org/doi/full/10.1056/NEJMoa073121


    An early case adverse event: (Possibly unrelated)
    https://www.nejm.org/doi/full/10.1056/NEJMoa063842

    European Medicines Agency withdrawal assessment report:
    https://www.ema.europa.eu/en/documen...diatric_en.pdf

    Related British Medical Journal (BMJ) Articles:
    https://www.bmj.com/content/369/bmj.m1931
    https://www.bmj.com/content/346/bmj.f3037

    Market Segment Analyses for Flu Vaccines:
    https://www.prnewswire.com/news-rele...300771932.html

    Technical Papers: Dendritic cell & vascular interaction
    https://elemental.medium.com/coronav...g-2c4032481ab2
    https://www.cell.com/trends/immunolo...906(07)00185-8
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780311/
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300500/

    Programmed Necrosis
    https://www.nature.com/articles/s41418-018-0179-3
    https://www.nature.com/articles/nrm3683
    https://pubmed.ncbi.nlm.nih.gov/29237267/
    https://www.novusbio.com/antibody-ne...-and-autophagy
    https://www.cell.com/immunity/fullte...613(16)30210-2
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760320/
    https://en.wikipedia.org/wiki/RIPK1
    https://www.sciencedirect.com/topics...-biology/ripk1

    Molecular mechanisms of squalene:
    https://read.qxmd.com/read/32515732/...endent-pathway


    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591922/

    Mechanisms of necroptosis in T cells
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135356/
    https://pubmed.ncbi.nlm.nih.gov/32035657/

    Interferon Stimulated Genes
    https://www.cell.com/cell/fulltext/S...674(20)30500-6
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030454/
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313732/
    Last edited by indigopete; 27th July 2020 at 13:35.

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    Default Re: How to check if Charlie Ward's "flu vaccine" claims are true or false

    Ok, so in summary, what did you find?

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    Default Re: How to check if Charlie Ward's "flu vaccine" claims are true or false

    I don't want to post my personal conclusions though it should be a reasonably trivial exercise to detect either the presence or absence of at least some fundamental patterns in that data, certainly at the extremes.

    I did this research for myself, understanding the limitations of the data and my own personal biases to come to an informed personal view over conflicting claims "out there". But I'm not an authority on this subject and my conclusions wouldn't be either. On the other hand, the public domain resources cited above are reasonably authoritative, though not comprehensive, and people should use them to inform themselves to the extent they see fit.

    If they simply want a source of confirmation bias there is a smorgasbord of stated claim/counterclaim over the relationship between influenza vaccines and Covid-19 deaths out there to suit every taste.
    Last edited by indigopete; 27th July 2020 at 19:00.

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    Default Re: How to check if Charlie Ward's "flu vaccine" claims are true or false


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    Default Re: How to check if Charlie Ward's "flu vaccine" claims are true or false

    Quote Posted by indigopete (here)
    This looks "re-assuring": https://twitter.com/NeilClark66/stat...81814295961600
    The FDA he says “is the gold standard” of testing and ensuring safety and efficacy of the vaccines he wants us to have 2 or more doses of. What a slimy POS. He can’t even sit still when he spews this lying crap with an arrogant smug look on his face.

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