Alzheimer's: prevention and cure

[onawah]

Free video summit on prevention and cure for Alzheimer's

I get a newsletter from NaturalHealth365, all about alternative approaches to health, and this was in their latest issue:

NaturalHealth365 subscribers,

As you know, I just completed the Alzheimer's and Dementia Summit - in honor of my father.
The response was tremendous - because so many lives are being affected by this horrible disease.
Conventionally speaking, everything we've been told about Alzheimer's disease is nonsense!
Western medicine tells us that there 'is no cure for Alzheimer's disease.' And, that's exactly what my own family believes.
Most doctors merely evaluate a patient and prescribe ineffective (expensive) drugs that offer unwanted side effects.
But, what you won't hear about on Fox News, CNN, or even HBO is that in just a few short weeks, everything you've heard about Alzheimer's is about to change ... (for the better!)
Because that's when my friend Jeremy releases a groundbreaking new video series about natural ways to REVERSE Alzheimer's.
This is a wonderful follow-up to the Alzheimer's and Dementia Summit and I'm glad to see that this topic is getting the attention it deserves.
Click here to watch the preview of this FREE, 12-day event.

Source: https://youtube.com/watch?v=sXXucOu7rd0

The Alzheimer's Association won't be happy about this
In this upcoming video event, the most brilliant minds in Alzheimer’s research have come together in a free 12-day docu-series to share everything they’ve learned about REVERSING Alzheimer's disease.
(Sign up here: http://event.awakeningfromalzheimers...2c/?f1428=1014 )
This isn’t pie-in-the-sky wishful thinking. The 14 doctors interviewed for this event are reversing Alzheimer’s right now (today) - for hundreds of patients!
The event is called Awakening from Alzheimer’s, and it’s an inspiring beacon of hope for the millions around the world who’ve been touched by this devastating disease.
It’s hard to describe how it feels to finally see that Alzheimer’s CAN be defeated, and hear the stories of people who have actually done it.
You’ll just have to experience it for yourself.


To your continued success and great health,

-Jonathan Landsman, Host
NaturalHealth365.com

PS: Make no mistake - there are powerful forces at work that do NOT want you to see this kind of empowering information. The simple truth is that it's in their best interests to keep YOU in the dark!

But, they're in for a BIG surprise - when this video get out!

[Olaf]

According to Dr. Bodo Kuklinski the main causes for "Alzheimer" are:

• Beta blockers
• ACE inhibitors
• other hypertonus medicals
• statins (cholesterol lowering agents)

My observations fit into this.

[Mercedes]

The video sounds very promising but doesn't give a hint as to what is the treatment or cure, and that music is so uplifting, I've heard it before. I hope it is truthful.

[Longjohn]

Dear Friends,

I haven't seen any of these videos yet, but there are several other sources of information on Alzheimer's cures that might interest you. I list them below.

1) There have been many references to the recent work carried out by Dr. Dale Bredesen of UCLA. See the following links to get started:

http://newsroom.ucla.edu/releases/me...for-first-time

https://www.sciencedaily.com/release...0616071933.htm

There is also a book called 'The Atlas of Natural Cures' by Dr. Glenn Rothfeld that describes this and other interesting natural healing methods well:

https://pro.nutritionandhealing.com/...im&g=10&h=true

2) The Aged Garlic Extract (AGE) cure:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941700/

https://www.nexusmagazine.com/produc...-garlic-detail

http://www.totalhealthmagazine.com/C...EART-MIND.html

3) TC-2153 from Yale University:

http://news.yale.edu/2014/08/06/sear...r-step-forward

http://theselfimprovementgenie.com/5...estore-memory/

http://memoryhealerprogramreviews.strikingly.com/

If you need some more information, I will do my best to help you.

Kind regards,

John

[petra]

I stumbled on this one through one of my more trustworthy Facebook contacts this morning, and not able to confirm any of this, but sounds very promising! I'm including the part about Aluminum below

https://longevitybox.net/82-year-old...ing-her-diet-2

----quote from article below---

In an article titled Strong evidence linking Aluminum to Alzheimer’s, recently published in The Hippocratic Post website, Exley explained that:

“We already know that the aluminium content of brain tissue in late-onset or sporadic Alzheimer’s disease is significantly higher than is found in age-matched controls. So, individuals who develop Alzheimer’s disease in their late sixties and older also accumulate more aluminium in their brain tissue than individuals of the same age without the disease.

Even higher levels of aluminium have been found in the brains of individuals, diagnosed with an early-onset form of sporadic (usually late onset) Alzheimer’s disease, who have experienced an unusually high exposure to aluminium through the environment (e.g. Camelford) or through their workplace. This means that Alzheimer’s disease has a much earlier age of onset, for example, fifties or early sixties, in individuals who have been exposed to unusually high levels of aluminium in their everyday lives.”

His most recent study, published by the Journal of Trace Elements in Medicine and Biology in December 2016, titled: Aluminium in brain tissue in familial Alzheimer’s disease, is one of the many studies that he and his team have conducted on the subject of aluminum over the years. However, this study in particular is believed to be of significant value, because it is the first time that scientists have measured the level of aluminum in the brain tissue of individuals diagnosed with familial Alzheimer’s disease. (Alzheimer’s disease or AD is considered to be familial if two or more people in a family suffer from the disease.)

According to their paper, the concentrations of aluminum found in brain tissue donated by individuals who died with a diagnosis of familial AD, was the highest level ever measured in human brain tissue.

Professor Exley wrote:

“We now show that some of the highest levels of aluminium ever measured in human brain tissue are found in individuals who have died with a diagnosis of familial Alzheimer’s disease.

The levels of aluminium in brain tissue from individuals with familial Alzheimer’s disease are similar to those recorded in individuals who died of an aluminium-induced encephalopathy while undergoing renal dialysis.”

[Hughe]

Source: https://on.rt.com/awb2

Drug reverses age-related cognitive decline within days, potentially turning the tide on diseases like Alzheimer’s and dementia


A new study tested how effective a drug called ISRIB was in reversing age-related declines in memory and mental flexibility in mice. The team of scientists from the University of California, San Francisco (UCSF) found startling results.

The research suggests age-related cognitive losses may be caused by a kind of reversible physiological “blockage” rather than more “permanent degradation,” according to researcher Susanna Rosi.
Read more
Birth control for men? Scientists discover how to spot ‘winning’ sperm in breakthrough for non-hormonal male contraceptives Birth control for men? Scientists discover how to spot ‘winning’ sperm in breakthrough for non-hormonal male contraceptives

Instead, it appears that cognitive capacities are not irrevocably lost but have been blocked and lay dormant as a result of a mechanism known as the integrated stress response (ISR). This blockage is triggered by a “vicious cycle of cellular stress,” according to Peter Walter, a professor in the UCSF Department of Biochemistry and Biophysics.

Previous studies on mice involving ISRIB found that even brief treatment with the drug can restore normal brain function after a traumatic brain injury almost overnight.

Scientists view traumatic brain injuries as analogous to accelerated, age-related cognitive decline, so they wanted to test the drug in that arena by rebooting cells' protein production machinery after they become throttled by the mechanism.

The unwanted stress response can typically be triggered in response to irregularities in protein production in a cell, which may indicate viral infection or the presence of cancer. It slows down the cell's protein synthesis machinery as a precaution, but if it stays switched on for too long it can seriously impair cell function with drastic consequences for cognitive function.

“We've seen how ISRIB restores cognition in animals with traumatic brain injury, which in many ways is like a sped-up version of age-related cognitive decline,” said Rosi. “It may seem like a crazy idea, but asking whether the drug could reverse symptoms of aging itself was just a logical next step.”

In the new study, researchers trained mice to escape from a maze by finding a hidden platform, a difficult task involving lots of recall which is typically challenging for older mice.

Older animals who received small daily doses of ISRIB during their three-day training performed as well as their younger counterparts and far better than their contemporaries who didn't receive the treatment.

Weeks later, they trained the same mice to escape a maze whose exit changed on a daily basis, requiring more ongoing and adaptive mental flexibility than a mere recall task. The results mirrored the previous experiment, with treated elderly mice matching their younger counterparts and outperforming untreated older mice.

Researchers also conducted brain analyses the day after ISRIB treatment had been administered. To their astonishment, they found that the telltale signatures of neuronal ageing disappeared overnight: Electrical activity sparked more vibrantly in response to stimulation, much like a more youthful brain, while cells also appeared vastly more interconnected with each other.

The research may have far-reaching applications including treatments for degenerative neurological disorders such as Alzheimer's, dementia, multiple sclerosis and Parkinson's among others.

To sweeten the deal even further, researchers have observed no serious side effects, itself rather puzzling for such a critical mechanism. They suspect the dearth of side effects is due to the relatively low dose, in combination with quick effect.

“It almost seems too good to be true, but with ISRIB we seem to have hit a sweet spot for manipulating the ISR with an ideal therapeutic window,” Walter says.

[onawah]

Cheese Is One of the Most Neuroprotective Foods
by Dr. Joseph Mercola
February 20, 2021
https://articles.mercola.com/sites/a...rid=1088745401

"STORY AT-A-GLANCE
Out of 49 whole foods, cheese was “by far” the most protective food when it comes to avoiding age-related cognitive problems
Those who ate cheese daily had better fluid intelligence scores over time; red wine and lamb consumption also had a favorable effect
The researchers concluded that modifying your daily meal plans may minimize cognitive decline while adding cheese, red wine and weekly lamb may improve long-term cognitive function
When you eat natural cheese, you get valuable fats, proteins, vitamins, minerals and amino acids that protect your brain and overall health; raw grass fed cheese is best in terms of nutritional punch


What you eat has a powerful effect on brain health and can even influence your cognitive function long-term. In particular, a study of 1,787 adults revealed that out of 49 whole foods, cheese was “by far” the most protective food when it comes to avoiding age-related cognitive problems.1

Cheese has been unfairly vilified due to its saturated fat content, when in reality it’s a wholesome food that provides key nutrients many people are lacking, including healthy fats and vitamins. As the featured study shows, eating cheese daily may be a simple way to keep your brain sharp, even into your later years.

Eat Cheese Daily to Protect Your Brain
Researchers from Iowa State University measured what’s known as fluid intelligence (FI) among the study participants, who ranged in age from 46 to 77 when the study was completed. Fluid intelligence is the ability to “think on the fly” or solve problems without any prior knowledge of the problem at hand.

Research suggests that greater decline in fluid intelligence as you age is associated with an increased risk of Alzheimer’s disease,2 but dietary changes may influence fluid intelligence.

The study evaluated self-reported intake of 49 foods, including fruits and vegetables, fish, meat, bread, coffee and wine, and compared it to fluid intelligence trajectories among the participants, some of whom had a family history of Alzheimer’s disease while some did not.

Those who ate cheese daily had better fluid intelligence scores over time, while red wine consumption also had a favorable effect. Consuming lamb weekly also led to improved FI outcomes.3 Study author Auriel Willette, an assistant professor in Food Science and Human Nutrition, said in a news release:4

"I was pleasantly surprised that our results suggest that responsibly eating cheese and drinking red wine daily are not just good for helping us cope with our current COVID-19 pandemic, but perhaps also dealing with an increasingly complex world that never seems to slow down.

While we took into account whether this was just due to what well-off people eat and drink, randomized clinical trials are needed to determine if making easy changes in our diet could help our brains in significant ways."

The researchers concluded that modifying your daily meal plans may minimize cognitive decline while adding cheese, red wine and weekly lamb may improve long-term cognitive function.5 Study author Brandon Klinedinst, a neuroscience Ph.D. candidate at Iowa State, further highlighted the power of diet on your long-term brain health:6

"Depending on the genetic factors you carry, some individuals seem to be more protected from the effects of Alzheimers, while other seem to be at greater risk. That said, I believe the right food choices can prevent the disease and cognitive decline altogether.

Perhaps the silver bullet we're looking for is upgrading how we eat. Knowing what that entails contributes to a better understanding of Alzheimer's and putting this disease in a reverse trajectory."

Cheese Is a Brain Food
Cheese isn’t widely known as a “brain food” — but it should be. For instance, consuming mold-fermented cheese, like camembert, for three months had beneficial effects on brain-derived neurotrophic factor (BDNF) levels in older women with mild cognitive decline.7

BDNF is highly involved in the growth and survival of nerve cells specifically,8 and low levels of BDNF have been connected to the development of dementia and Alzheimer’s disease,9,10 as well as other brain disorders such as Parkinson’s disease, Huntington’s disease and schizophrenia.11

Bioactive peptides produced by milk fermentation during the cheese-making process may also have antioxidant properties that play a role in enhancing cognitive ability.12

Intake of camembert cheese has been shown to prevent Alzheimer’s disease in an animal study, and it’s thought that novel lactopeptides in fermented dairy products may improve memory function and cognitive decline.13 When researchers screened peptides generated from whey proteins during cheese manufacturing, Trp-Tyr (WY)-containing peptides were found to improve memory function in mice.14

They worked by inhibiting monoamine oxidase-B activity (MAO-B) — MAO-B has been suggested as a biomarker of neuroinflammation in neurodegenerative disorders15 — thereby helping to prevent age-related cognitive decline.16 A host of other studies also hint at the brain protective potential of cheese, including:

Consuming cheese or other dairy products once a week was associated with higher cognitive function than not consuming it17
Over 17 years of follow-up, greater milk and dairy intake reduced the risk of dementia, especially Alzheimer’s disease, in the Japanese population18
Among men, high intake of dairy products was significantly associated with better short-term memory19
Why Cheese Is Good for You
Cheese contains nutrients that are beneficial for your whole body, including the powerful nutritional triad of calcium, vitamin D and vitamin K2, which together channel calcium into your bones and teeth while keeping it out of your arteries.

Aside from natto, cheese is the food with the highest menaquinone, or vitamin K2, concentrations, but levels vary depending on the type of cheese. Dutch hard cheeses such as gouda and edam have relatively high concentrations, as do French cheeses such as Munster cheese.20

In addition to bone health, vitamin K2’s role in heart health is well-noted. In fact, in one study, those who had the highest amount of vitamin K2 were 52% less likely to experience severe calcification in their arteries and 57% less likely to die from heart disease over a seven- to 10-year period.21

When you eat cheese, you also get high-quality protein and amino acids, omega-3 fats and vitamins and minerals, including calcium, zinc, phosphorus, vitamins A, D, B2 (riboflavin), and B12.22 You’ll also get beneficial CLA (conjugated linoleic acid), a powerful cancer-fighter, particularly when you eat grass fed cheese.

Cheese Wards Off Chronic Disease
The nutrients in cheese add up to whole-body effects that may help prevent chronic disease even outside of your brain. In a study published in BMJ Open Diabetes Research and Care, for instance, researchers noted that participants who ate at least two servings of dairy products each day had a lower risk of high blood pressure and Type 2 diabetes.23 In addition, they were at lower risk for metabolic syndrome.

“Emerging evidence suggests that dairy foods, particularly whole fat dairy and fermented dairy (e.g., cheese or yogurt), may influence diverse pathways and have favorable metabolic effects,” the researchers explained.24 This is another way cheese may be neuroprotective, as conditions like diabetes take a toll on your brain health. Diabetes even ages your brain about five years faster than normal.25

An inverse relationship has also been found between the daily amount of fermented dairy consumed and the development of heart disease. For instance, those who had the highest intake of fermented dairy products had a 27% lower risk of heart disease in one study.26

Greater cheese consumption, in particular, is also linked with a lower risk of heart disease.27 Writing in the British Journal of Nutrition, researchers noted that dairy products shouldn’t be vilified due to their fat content but, rather, “The whole food matrix should be considered,” and:28

“Based on experimental and prospective studies to date, it seems plausible that manufacturing processes, such as fermentation, could influence how different dairy products affect the development of CVD [cardiovascular disease].

Fermentation process includes adding live bacteria to dairy foods, which can act as probiotics and result in multiple cardiometabolic benefits. Some of these bacteria, used for example in cheese making, form vitamin K2, which has been associated with lower risk of CHD [coronary heart disease].”

The Type of Cheese Matters
All cheese is not created equal, particularly if it’s highly processed. Processed cheese or “cheese food” is not a health food and should be avoided, while natural cheese is a whole food — a simple fermented dairy product made with nothing more than a few basic ingredients — milk, starter culture, salt and an enzyme called rennet.

You can tell a natural cheese by its label, which will state the name of the cheese variety, such as "cheddar cheese," "blue cheese," or "brie." Real cheese requires refrigeration. Taking it up a notch is grass fed cheese, which is made from the milk of grass fed cows. There are a number of reasons to seek out grass fed dairy products as much as possible.

For foodies, the seasonal variations in flavor are a huge draw. For the health-conscious, milk from cows raised primarily on pasture has been shown to be higher in many nutrients, including vitamin E, beta-carotene and the healthy fats omega-3 and CLA.29

On an environmental level, grass fed dairy also has a considerably reduced footprint compared to the way most dairy is produced on concentrated animal feeding operations (CAFOs). You may find grass fed dairy farmers who have not yet gone through (or who cannot afford to go through) the USDA’s organic certification process. In that case, speak to the farmer directly to find out about how the animals are raised.

You can also look for the American Grassfed Association (AGA) logo, a much-needed grass fed standards and certification for American-grown grass fed meat and dairy.30 Raw grass fed cheese is also highly recommended and, because raw cheese is not pasteurized, natural enzymes in the milk are preserved, increasing its nutritional punch.

Overall, grass fed cheese is a healthy whole food to include in your diet, one that offers protection for your brain and your health as a whole. It’s not, however, the only food that’s beneficial for your brain. If you’re looking for more tips on what to eat to protect your cognitive function, focus on avoiding processed fast foods and eating plenty of brain-boosting foods, like small cold-water fish, cruciferous veggies, leafy greens and pastured, organic eggs, instead."

Sources and References
1, 4, 6 Science Daily December 10, 2020
2, 3, 5 J Alzheimers Dis. 2020;78(3):1245-1257. doi: 10.3233/JAD-201058
7 J Am Med Dir Assoc. 2019 Dec;20(12):1509-1514.e2. doi: 10.1016/j.jamda.2019.06.023. Epub 2019 Sep 24
8 Arch Med Sci. 2015;11(6):1164-78
9 Aging Dis. 2015;6(5):331-41
10 Int J Mol Sci. 2019;20(2)
11 J Biomed Sci. 2016;23:17
12 British Journal of Nutrition February 22, 2011
13, 14, 16, 17 Neurobiology of Aging December 2018, Volume 72, Pages 23-31
15 Science Direct, Monoamine Oxidase B
18 Journal of the American Geriatrics Society June 10, 2014
19 Clinical Nutrition April 2016, Volume 35, Issue 2, Pages 507-513
20 Nutrients. 2018 Apr; 10(4): 446
21 The Journal of Nutrition November 1, 2004: 134(11); 3100-3105 (The Rotterdam Study)
22 Dairy Council of California
23, 24 BMJ Open Diabetes Research and Care, 2020;8:e000826. doi: 10.1136/bmjdrc-2019-000826
25 Ann Intern Med. 2014;161(11):785-793
26 British Journal of Nutrition, 2018;120(11)
27 Eur J Nutr. 2017 Dec;56(8):2565-2575. doi: 10.1007/s00394-016-1292-z. Epub 2016 Aug 12
28 British Journal of Nutrition October 29, 2018
29 La Crosse Tribune December 19, 2013
30 American Grassfed December 21, 2016