What Supplements Might be Missing from your Health Regimen?

[onawah]

DMSO Is a Miraculous Therapy for Pain and Tissue Injury
Analysis by A Midwestern Doctor
October 25, 2024
https://articles.mercola.com/sites/a...&rid=148258852

https://media.mercola.com/ImageServe...injury-pdf.pdf

(Many hyperlinks in the article not embedded here)

"Story at-a-glance
The standard approach for managing pain and musculoskeletal injuries often involves NSAIDs (e.g., ibuprofen), which are linked to serious risks, including tens of thousands of deaths annually
DMSO is a highly effective, natural pain reliever that has helped individuals disabled by chronic pain (e.g., from failed spinal surgery or severe arthritis) regain their quality of life.
It also addresses conditions that other therapies struggle to alleviate like complex regional pain syndrome
DMSO is effective in promoting wound healing and healthy scar formation, making it remarkable for surgical recovery and burns
DMSO has an 80% to 90% success rate for treating a wide range of musculoskeletal conditions, including arthritis, back and neck strains, sprains, bursitis, and traumatic injuries.
Its rapid and dramatic effects have made it popular among professional athletes for quick recovery

Modern medicine often sidelines "miracle" drugs that work too well. Despite decades of evidence showing that the naturally occurring chemical Dimethyl Sulfoxide (DMSO) is a remarkably safe and versatile treatment for a range of challenging conditions — such as strokes, head trauma, spinal cord injuries, dementia, and even Down Syndrome — it has been largely overlooked.
See; https://www.midwesterndoctor.com/p/d...ons-from-brain

This sidelining is particularly remarkable as DMSO is also one of the most effective treatments for acute and chronic pain, musculoskeletal injuries, and chronic degenerative conditions (e.g., arthritis).

DMSO, Nature’s Healer
DMSO is a powerful, natural compound with several unique properties that make it an incredibly versatile healing agent:

Rapid absorption — When applied to the skin or ingested, DMSO quickly spreads throughout the body.

Cellular protection — It shields cells from lethal stressors like burns, frostbite, blood loss, radiation, and shockwaves, and can rescue already damaged cells on the verge of dying.

Safety profile — DMSO is extremely safe,1 and in almost all cases, its only side effects are temporary skin irritation or creating a garlic-like odor. In contrast, the standard of care (NSAIDs) kill tens of thousands of Americans each year and are the leading cause of drug induced hospital admissions.

Conduction blocking — DMSO selectively blocks pain signals from small nerve fibers (e.g., C fibers)2,3,4 which are often involved in chronic pain (e.g., DMSO is one of the most effective treatments for complex regional pain syndrome). This blocking effect is reversible and doesn't cause tolerance.

Choline esterase inhibition — By inhibiting acetylcholinesterase,5,6,7,8 DMSO boosts acetylcholine levels, enhancing parasympathetic function and reducing pain.

Anti-inflammatory action9 — DMSO is incredibly effective at rapidly reducing inflammation (e.g., it lowers inflammatory cytokines, scavenges free radicals, and drains edema that would otherwise compress tissues).

Muscle relaxation — DMSO rapidly relaxes skeletal muscles, easing pain from tension and spasms.10,11,12

DMSO and Tissue Healing
DMSO greatly improves wound healing (e.g., from burns or surgeries). For example:

•A study of 1371 chronic skin wounds that had often remained unhealed for years (e.g., infected ulcers or severe burns) found 95.04% had a rapid and complete recovery (e.g., no burn scars).13 Likewise, a systematic review found DMSO effectively treated ulcers.14

•Numerous studies show that DMSO accelerates limb regeneration in animals15 and surgical wound healing in humans.16 It also enhances the viability of skin grafts and flaps, offering benefits for plastic and reconstructive surgery.17,18,19,20,21,22

•Animal studies have shown DMSO increases the tensile strength of surgical scars23,24 (which significantly improves surgical outcomes), decreases experimentally induced intestinal adhesions25 (a common complication of abdominal surgeries) by 80%, prevents hypertrophic (excessive) scar formation.26

•Human studies show DMSO can flatten and loosen keloid scars27 and gradually eliminate subcutaneous fibrosis induced by radiation.28

•Finally, DMSO is also sometimes used to repair keloid scars. For example, in one study of ten people with keloids, applying 50% to 80% DMSO a couple of times a day induced scar flattening with the loosening of the collagen surrounding the fibrous bundles.29 Similarly, another study found DMSO eliminated (through a gradual softening and reduction of it).30

DMSO and Musculoskeletal Injuries
Many of the early adopters of DMSO went from skeptics to believers because of the rapid and dramatic improvements they saw from it healing acute injuries (e.g., as they had patients with debilitating bursitis in the shoulder recovering within minutes of receiving DMSO).

As it was far safer and more effective than any other way to treat musculoskeletal injuries, joint disorders or chronic pain, DMSO was rapidly adopted by doctors and pharmaceutical companies across the country (e.g., millions were invested to bring DMSO products to market and hundreds of thousands of Americans had life-changing benefits from it).

https://x.com/MidwesternDoc/status/1845727169273868623

Unfortunately, as DMSO’s use was skyrocketing, on November 10, 1965, the FDA decided to globally ban all research on it by falsely claiming it was incredibly dangerous. Because of this, there was an explosion and then sudden disappearance of DMSO research, which sadly continued even with Congress repeatedly trying to get the FDA to overturn their indefensible prohibition of DMSO.

Note: A detailed review of DMSO’s extensive safety data and toxicology studies can be viewed here. https://www.midwesterndoctor.com/p/t...ory-and-safety

As a result, very little knowledge now exists of DMSO’s use in human musculoskeletal injuries other than it existing in a few FDA approved products (where it typically is combined with another agent). Remarkably however, it is fully permitted in veterinary medicine (which led to a lot of Americans using DMSO that was "meant for horses") where it is frequently utilized for musculoskeletal injuries. Those forgotten studies include:

A 1964 study,31 where 22 out of 25 patients with subacromial bursitis experienced a rapid improvement within 30 minutes of DMSO, while in chronic cases 32 of 40 patients improved and in some patients, a reduction in shoulder calcium deposits was also noted (which in a later 1967 study,32 were shown on X-ray to disappear following DMSO).








In that study, its author (a former president of the Aerospace Medical Association43) remarked:

"I am convinced that the topical application of DMSO in the treatment of acute musculoskeletal conditions is a striking and significant therapeutic contribution. During the period of time I conducted clinical investigation with this medication, I practically discarded physical therapy as treatment for musculoskeletal problems because the rehabilitation of my patients was so prompt with DMSO.

There was little or no necessity to prescribe narcotics and tranquilizers since pain was promptly mitigated following topical application of DMSO."

He then conducted a follow-up double-blind study44 on patients with sprains, strains, bursitis, or tendinitis which found DMSO significantly improved those conditions and reduced the time patients lost from work.

A 1994 blinded study45 gave 157 patients with acute tendinopathies (e.g., tennis elbow) 10% DMSO gel or a placebo ointment three times a day for 14 days within 3 days of symptoms starting. Pain of movement under loading and the mobility of the joints were significantly improved after, respectively, 3 and 7 days of treatment with DMSO. After 14 days on DMSO, a further improvement was observed, and 44% of the patients (and 9% of placebo) were pain-free.

Note: DMSO has also been reported to be effective for carpal tunnel syndrome46 (and other hand issues like trigger fingers). For those struggling with carpal tunnel syndrome, I discussed our approaches to the disorder here. https://www.midwesterndoctor.com/p/t...-carpal-tunnel

Finally, a 1967 analysis47 of 76 studies using topically applied (90%) DMSO for musculoskeletal conditions found 72% improved. Specifically:



Note: The review also included 102 Traumas (contusion, fracture, etc.), 29 Tenosynovitis, 27 Neuritis, 20 Muscle spasms, 20 unspecified types of arthritis, and 220 miscellaneous issues (e.g., fibrositis, epicondylitis, synovitis, calcific tendinitis).

To quote the authors:

"It is difficult to declare that a drug has efficacy on the basis of uncontrolled studies in a heterogeneous group of diseases. However, from these data and from discussions with many of our investigators, we feel that DMSO is a unique and effective agent for the treatment of many acute musculoskeletal disorders.

Beneficial results are unpredictable, but they occur frequently and are sometimes dramatic, particularly in acute conditions, which require low doses and short treatment periods. In chronic conditions, improvement occurs at a lower rate and is less dramatic."

Finally, at a symposium on DMSO,48 data on 9,521 patients were presented, which showed DMSO was effective therapy in a wide variety of acute traumatic conditions, in acute and chronic subacromial bursitis, osteoarthritis, gouty arthritis, and in some patients with rheumatoid arthritis (along with other conditions such as early Dupuytren’s contracture).

Note: A later 1981 study49 also found DMSO was superior to indomethacin in the treatment of gout.

Sports Injuries
"What I like about DMSO is that you don’t have to interrupt your training every time you get a minor pull or sprain. It doesn’t pump you up like certain pills. It’s simply a very useful thing to use for simple athletic injuries.

Some people have told me that you shouldn't use it because it might mask the pain of a serious injury, but a good athlete knows his body well. Even when I’m using DMSO, I know when I can push and when I can’t." — Al Oerter, a discus thrower and the first American to win 4 consecutive Olympic gold medals.50

One of the greatest challenges professional athletes face are sports injuries which prevent them from returning to the field, particularly since many sports injuries are a product of micro-injuries building up until a critical point is passed (e.g., from adhesions and scars in the soft tissue).

In turn, since DMSO both heals micro-injuries and rapidly treats traumatic injury (returning them to full functionality), DMSO was rapidly adopted by professional athletes once they realized what it could do for their careers (and being off the field was often devastating to their careers).

In turn, due to the voice their position afforded them, a few professional athletes (e.g., Atlanta Falcons Quarterback June Jones51 — who now is a coach52) became some of the most impactful advocates for DMSO (e.g., Jones stated in Congressional testimony53 that "veterinary" DMSO was widely used but athletes were afraid of publicly discussing it). Likewise, in 2013, a Dallas Cowboys Lineman stated:54

"You get it [from] the veterinarian and it goes right to the bloodstream. It’s an ointment that’s like anti-inflammatory. You put it on your skin and you put it on a muscle, and I guarantee you, in about 30 minutes you’d feel it. It wasn’t on the list [of banned substances] ... we used DMSO and people knew it. Everyone knew about it."

Furthermore, in his riveting testimony, Jones provided cases that left the Congressmen in disbelief, such as a teammate with a bone chip and a torn ligament (which would require months of recovery and hence end their season) taking DMSO immediately after the injury and 7 or 8 days later returning to the field (with the bone chip remaining but no longer causing issues).

Likewise, at that Congressional hearing, the former team physician for the Oakland Raiders55 testified that he’d used 70% topical DMSO on a careful and controlled basis for his players 20 to 30 times a year for 5 years. From this, he observed that DMSO was the most beneficial when given in the first 3 to 4 days of an acute injury where a muscle or joint had severe swelling, particularly of the extremities, especially the ankle, elbow, hands, or wrist.

Overall, he stated that DMSO provided good to excellent results 70% to 80% of the time (e.g., through reduced pain and swelling) and the players felt they were able to return to play 50% to 75% faster than they had from similar injuries in the past. Conversely, they did not find DMSO was helpful for chronic injuries, but this may have been due to it not being used long enough for the effects to kick in.

Note: He also emphasized that DMSO would transform the field of occupational medicine. I fully agree with his assessment, especially given just how frequently Worker’s Comp fails to help its patients.

Similarly, podiatrist Lowell Scott Weil (who was the physician for both the Chicago Bears and the United States Olympic gymnastics team) used DMSO on a regular basis (particularly injured gymnasts).

After 12 years of using it, he shared,56 he’d seen it rapidly heal injuries (e.g., he had a gymnast who suffered an ankle sprain expected to end her season, but instead quickly recovered and made the U.S. Olympic team, and a football player who tore his hamstring but was able to rapidly return to the field).

Overall, he had a 60% treatment success rate and saw the best response to DMSO for tendinitis, myositis, and post-injury situations such as muscle pulls, ankle sprains, strains, and tears of the soft tissue (and conversely the only side effects he had were skin irritation). Additionally, he also used it for arthritic patients (especially rheumatoid arthritis) with many having dramatic relief. Many other compelling anecdotes exist.

For example, this book57 discusses the experience of an Oregon State track coach and early adopter of DMSO who had many amazing stories of DMSO treating hamstring and achilles tendon injuries such as an athlete being able to return to the field at full capacity 3 days after a normally disqualifying hamstring injury and the story of a blind long distance runner who was able to run due to DMSO fixing musculoskeletal injuries and (according to the author) then played a pivotal role in opening the sport to women.

Note: A major problem in certain sports like football is repeated concussions (which are now recognized to put them at risk for cognitive impairment and dementia later in life). As discussed in the first part of this series, https://www.midwesterndoctor.com/p/d...ons-from-brain
...in addition to treating strokes and spinal cord injuries, DMSO is also immensely helpful for mitigating the effects of concussions.

Research also directly demonstrates DMSO’s utility in sports medicine:

•A 1965 study58 treated 47 injured athletes from a wide range of sports (e.g., tennis, diving, or wrestling) by applying 90% DMSO applied to the injured areas 3 times a day initially and then after 2 days, twice a day. The 30 acute traumas (e.g., sprains, strains, dislocations, serious cuts) were observed to rapidly resolve, sometimes "so spectacularly as to compel us to urge our patients to observe greatest caution in order to avoid further damage to a joint."

The 10 chronic conditions (e.g., tennis elbow) and 7 conditions resulting from prolonged immobilization also responded rapidly and those athletes were often able to quickly return to the field. These results and the lack of observed adverse events led the investigators to argue DMSO urgently needed to become the standard of care in sports medicine.

•A study59 of 78 patients (mostly athletes) with overstrained tendons received Dolobene gel (15% DMSO, dexpanthenol and heparin) for 2 to 3 weeks, with over 50% having a significant improvement of symptoms and those improvements including a 94% improvement in pain, a 55% improvement of swelling, 95% improvement of redness and 92% improvement of warmth.

•A study60 gave Dolobene gel to 30 athletes with soft tissue injuries of the upper and lower extremities twice daily for 4 weeks. There were 4 athletes with contusion of the shoulder, 8 with distortion and contusion of the knee joint, 8 with muscle, tendon and ligament lesions, and 10 with distortion of the ankle joint.

Following DMSO, 10 had an excellent response (improvement), 5 had an excellent to good response, 10 had a good response and 5 had a moderate response. Specifically, pain, inflammation, swelling, reabsorption of hematomas, tenderness and recovery time were assessed.

•A study61 gave Dolobene gel and ultrasound to 15 subjects who had received a blunt tissue trauma (without fracture) to the lower extremity within the last 24 hours. Compared to 15 placebos, the treatment resulted in a faster relief of pain, reduction of edema, and recovery of mobility.

•A 1966 study62 of 28 professional baseball players found that giving them DMSO after injuries caused their downtime be one third of what was observed by the treating physician in the previous year with 42 players.

Note: While not quite the same as getting tackled, I’ve also come across cases63 of individuals taking DMSO immediately after getting hit by a car while crossing the street (which caused injuries but no fractures) and immediately fully recovering.

Conclusion
Many of the benefits of DMSO are so extraordinary that they understandably invite a healthy degree of skepticism, and it is for that reason I have spent months carefully compiling the evidence behind it. Likewise, after presenting the initial case for DMSO to the readership of the Forgotten Side of Medicine, I put out a call for what those who’d tried DMSO had experienced.

In those comments, dozens of readers reported remarkable experiences of DMSO, many of which mirror those described throughout this article, but also other even more remarkable ones (e.g., for a child with Down Syndrome, a man with Parkinson’s and a woman who had severed her spinal cord).

The suppression of DMSO has always deeply bothered me, and in turn, I feel incredibly grateful to be alive at a time when the world is ready to learn of the suppressed medical truths many before me (e.g., the DMSO researchers) devoted their lives to bring to humanity.

Furthermore, I believe this is just the start, as beyond open platforms like Twitter (X) rapidly eroding the public’s trust in corrupt medical dogmas, I know through trusted confidants directly connected to RFK Jr. that the next four years offers an unprecedented opportunity to begin rectifying many of the previously insurmountable problems that have plagued our health care system and make America Healthy Again.

Author's note: This is an abridged version of a longer article that goes into greater detail on the points mentioned here, others not as extensively covered (e.g., the wealth of evidence DMSO is a life-changing pain treatment), and guidance for topical DMSO use (e.g., dosing, therapeutic precautions and where to obtain it).

That article and its additional references can be read here (along with a companion article discussing DMSO’s remarkable utility for a variety of musculoskeletal injuries and chronic pain conditions and an article about how DMSO treats a variety of "incurable" autoimmune and genetic disorders).

A Note from Dr. Mercola About the Author
A Midwestern Doctor (AMD) is a board-certified physician from the Midwest and a longtime reader of Mercola.com. I appreciate AMD's exceptional insight on a wide range of topics and am grateful to share it. I also respect AMD’s desire to remain anonymous since AMD is still on the front lines treating patients. To find more of AMD's work, be sure to check out The Forgotten Side of Medicine on Substack."

Sources and References
1 The Forgotten Side of Medicine, October 12, 2024
2, 3 Exp Neurol. 1969 Jun;24(2):272-6
4 Neurosci Lett. 1993 Feb 19;150(2):145-8
5 ACS Chem Neurosci. 2017 Dec 20;8(12):2618-2625. doi: 10.1021/acschemneuro.7b00344. Epub 2017 Oct 16
6 Brain Res. 1991 Dec 6;566(1-2):329-32. doi: 10.1016/0006-8993(91)91719-h
7 Biochem Pharmacol. 1983 Jan 1;32(1):151-8
8 Nature. 1966 Oct 22;212(5060):405
9 The Forgotten Side of Medicine, September 29, 2024
10 Proc Soc Exp Biol Med. 1966 May;122(1):103-7
11 Ann N Y Acad Sci. March 1967, Volume 141, Issue 1, Pages 310-325
12 DMSO Symposium. Vienna: Berlin, Saladruck. Vol. 21. 1966
13 Ann N Y Acad Sci. 1975 Jan 27:243:408-11
14 Wounds UK 15(15):361-370, November 2003
15 Ann N Y Acad Sci. January 1975, Volume 243, Issue 1, Pages 257-268
16 Klin Khir (1962). 19881):1-3
17 DMSO.org, March 12, 1993
18, 22 Aesthet Surg J. 2005 Mar-Apr;25(2):201-9
19 Otolaryngol Head Neck Surg. 1994 Feb;110(2):228-31
20, 21 Plast Reconstr Surg. 2007 Dec;120(7):1819-1822
23 Am Surg. 1966 Jun;32(6):421-4
24 La Presse Medicale, 01 Jan 1967, 75(1):20
25 Arch Surg. 1965 Dec;91(6):920-3
26 J Plast Reconstr Aesthet Surg. 2017 Apr;70(4):509-517
27, 29 Ann N Y Acad Sci. March 1967, Volume 141, Issue 1, Pages 638-645
28, 30 Ann N Y Acad Sci. 1967 Mar 15;141(1):603-12
31 Northwest Med. 1964 Mar:63:167-8
32, 34, 35 Ann N Y Acad Sci. March 1967, Volume 141, Issue 1, Pages 506-516
33 JAMA. 1965;192(4):309-313
36 Ann N Y Acad Sci. March 1967, Volume 141, Issue 1, Pages 586-598
37 Ann N Y Acad Sci. 1967 Mar 15;141(1):572-85
38 Ann N Y Acad Sci. March 1967, Volume 141, Issue 1, Pages 532-550
39 A Midwest Doctor, September 25, 2024
40 Ann N Y Acad Sci. 1967 Mar 15;141(1):599-602
41 Ann N Y Acad Sci. 1967 Mar 15;141(1):569-71
42 Ann N Y Acad Sci. March 1967, Volume 141, Issue 1, Pages 496-505
43 Aeropsace Medical Association
44 Curr Ther Res Clin Exp. 1971 Aug;13(8):536-40
45 Fortschr Med. 1994 Apr 10;112(10):142-6
46, 63 Amazon, The DMSO Handbook for Doctors
47, 48 Ann N Y Acad Sci. March 1967, Volume 141, Issue 1, Pages 517-523
49 Terapevticheskii Arkhiv, 01 Jan 1981, 53(7):127-129
50 Amazon, DMSO: The True Story of a Remarkable Pain-Killing Drug
51, 53 UPI Archives, December 17, 1981
52 Wikipedia, June Jones
54 New York Post, February 8, 2013
55 Dr. Graham Reedy (Archived)
56 Amazon, DMSO: Nature's Healer
57 Amazon, The Persecuted Drug: The Story of DMSO
58 Gazz. Intern. Med. Chir. 70 (1965): 1605
59, 60, 61 Springer Book Archive, DMSO, 1985, Neue Erfahrungen in der Behandlung des Sehnenüberlastungssyndroms, Pages 54–57
62 DMSO Symposium. Saladruck, Berlin, 1966

[meat suit]

DMSO sounds very interesting, I have never tried it.
I have an ongoing shoulder/arm issue that might benefit.
Does anybody have a recommendation for a UK available brand ?

[Listkov]

DSMO is an interesting one. Biggest downside is that if you take too much your sweat will start smelling like it. Like garlic, I might've blown a pretty big opportunity because of it

I use it as a solvent for transdermal (on the skin) application of vitamins and supplements. It drastically increases the bioavailability of most of them you can get in powder form. Sometimes dissolves better if you add a little alcohol. The corollary to this enhanced bioavailability is that it applies for everything. So don't let it touch most plastics or you'll be getting an equal dose of pepsi bottle extract into your bloodstream

[Vangelo]

I have been using DMSO topically for a week now with significant reduction in pain (better than 66% easy). Within 2 hours of the first application I noticed a difference. I have significant pain in my Achilles and the side of my heel. I purchased the roll on product with 70% DMSO and 30% Aloe. I shake the container before application and I wash my feet and then rinse with bottled water to make sure there is no chlorine or fluoride residue from my tap water.

[grapevine]

The Supplements That ACTUALLY WORK

Source: https://youtube.com/watch?v=KHTDAnsSO5k

If you’re wondering about supplements for specific health issues, this is for you. In this video, we’re going to talk about the best supplements for a range of common health conditions. Learn about the top supplements that have worked for thousands of people!

0:00 Introduction: Best supplements for health conditions
1:39 Vitamin D benefits
3:39 Magnesium glycinate
6:06 Betaine hydrochloride
6:40 Zinc carnosine
6:50 Selenium
7:32 Vitamin B1
8:21 Calcium lactate
8:48 Iron
8:58 Potassium
9:15 Coenzyme Q10
9:25 Tocotrienols
9:45 TUDCA
10:07 Iodine
10:20 Vitamin C
10:30 Probiotics and biotin
10:44 Manganese and NAC
11:00 Mastic gum and melatonin
11:22 Niacin
11:35 Clove oil

25 TOP SUPPLEMENTS THAT REALLY WORK (Downloadable File): https://drbrg.co/40hy54r
1. Vitamin D is one of the best supplements for immune support. It can help with autoimmune diseases, cancer, and AIDS. It’s also beneficial for the following health concerns:
•Depression
•Glaucoma
•Low back pain
•Hip pain
•Deep bone pain
•Tumors
•Hair loss
•Dermatitis

Always take vitamin D supplements with cofactors magnesium, zinc, and vitamin K2

2. Magnesium glycinate is beneficial for the following:
•Blood sugar
•Migraines
•Sleep
•Prevents clotting
•Supports healthy blood pressure
•Prevents muscle cramps
•Prevents arrhythmias
•Improves energy
•Prevents kidney stones

3. Betaine hydrochloride helps with heartburn and indigestion. It helps to acidify the stomach and keep the valve at the top of the stomach closed.

4. Zinc carnosine is the best remedy for ulcers and can help calm down gastritis.

5. Selenium is beneficial for people with AIDS and Hashimoto’s.

6. Vitamin B1 is an excellent remedy for nervous tension, worry, stress, anxiety, and restless legs syndrome.

7. Benfotiamine is a fat-soluble form of vitamin B1 that’s beneficial for peripheral nerve issues.

8. Calcium lactate is beneficial for chronic coughing.

9. Iron is beneficial for low blood pressure and energy, but choose food sources of iron rather than supplements.

10. Potassium is essential and often beneficial for salt-sensitive people. You need 4700 mg every day!

11. Coenzyme Q10 is essential if you’re on statins.

12. Tocotrienols are the most potent form of vitamin E. They are beneficial for fibrosis, chest pain, infertility, and the arteries.

13. TUDCA is a type of bile salt that is even good for neurological problems!

14. Iodine helps with fibrocystic breast and regulates excess estrogen.

15. Vitamin C is good for collagen and bleeding gums.

16. Probiotics are vital, especially if you consume a lot of diet sodas.

17. Biotin is beneficial for your hair, nails, and skin.

18. Manganese is good for tourettes and tics.

19. NAC supports the liver and can help eliminate toxins

20. Mastic gum can help with gastritis.

21. Melatonin is beneficial for sleep.

22. Niacin is good for anything related to cholesterol.

23. Clove oil is beneficial for tooth or gum pain.

Dr. Eric Berg DC Bio:
Dr. Berg, age 59, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media.

[onawah]

Industry Scandal: The Loss of Nutrients

Posted by onawah (here)
Industry Scandal: The Loss of Nutrients
by Dr. Joseph Mercola
November 02, 2024
https://articles.mercola.com/sites/a...&rid=154123558

https://media.mercola.com/ImageServe...t-loss-pdf.pdf

Source: https://youtube.com/watch?v=Ax0SIbxgqDw

"Story at-a-glance
Modern farming practices and seed hybridization have significantly reduced the nutritional content of fruits and vegetables over the past 60 years, with average declines of 16% for calcium, 27% for vitamin C and 50% for iron
The focus on higher yields, longer shelf life and visual appeal in crop development has led to a trade-off in nutrient density, particularly evident in hybrid tomatoes compared to heirloom varieties
Four multinational corporations control two-thirds of the global seed market, leading to loss of biodiversity, farmer dependence on hybrid seeds and exploitative labor practices in seed production
The nutrient decline in produce contributes to increased risk of deficiencies, reduced antioxidant intake and rising chronic diseases, leading to greater reliance on dietary supplements
Solutions include supporting seed banks, practicing regenerative agriculture, increasing consumer awareness and implementing policies that prioritize soil health, protect farmers' rights and enforce fair labor practices in seed production

The documentary "Industry Scandal: The Loss of Nutrients" exposes how modern farming practices and seed hybridization have dramatically reduced the nutritional content of our fruits and vegetables over the past 60 years.

The evidence is clear: the food on our plates today is a shadow of what our grandparents ate. Not only has flavor been sacrificed on the altar of productivity and shelf-life, but critical vitamins and minerals have plummeted as well. This nutrient collapse has profound implications for public health that we're only beginning to understand.

The Ghost of Vegetables Past
The filmmakers begin their investigation at an unlikely location — the French Academy of Agriculture. Hidden away in this venerable institution, they discover a food composition table from 60 years ago detailing the exact nutrient content of fruits and vegetables at that time. Armed with this historical data, they set out to compare it to modern nutrient levels. The results are striking:1

"We discovered a little-known fact: fruit and vegetables have lost some of their vitamins and minerals. Take green beans for example: in 1960 they contained 65 milligrams (mg) of calcium for every 100 grams. In 2017 they contain no more than 48.5 milligrams. That's a quarter less calcium. The same thing for vitamin C — 19 mg at the time versus 13.6 mg."

This wasn't an isolated case. Examining data for the 70 most consumed fruits and vegetables revealed an alarming trend. According to the film, which is also known as "Seeds of Profit":2

"The results show a dramatic deterioration in the space of 60 years. All 70 fruit and vegetables have lost an average of 16% of their calcium, 27% of their vitamin C, and almost less than half of their iron levels."

These findings align with research conducted in the U.S. and U.K. American biochemist Donald Davis analyzed nutrient changes in 43 vegetables between 1950 and 1999, reaching similar conclusions.3 Davis’ study found statistically significant declines in six nutrients: protein, calcium, phosphorus, iron, riboflavin and vitamin C.

The median declines ranged from 6% for protein to 38% for riboflavin (vitamin B2), and the researchers suggest that these declines are most likely explained by changes in cultivated varieties between 1950 and 1999. Specifically, they said there may be "trade-offs between crop yield and nutrient content" in the newer varieties.

The Culprit: Agricultural ‘Progress’
What's behind this nutrient collapse? The documentary points to several factors, all stemming from the industrialization of agriculture:

•Hybridization for higher yields — Over the past 50 years, seed companies have focused on developing hybrid varieties that maximize yield and visual appeal. As Davis explains, "I think that most of these declines are caused by increases in yield. When yields go up, there's less nutrients per weight of the food. A lot of agricultural scientists may not know about how big these effects are. This is kind of embarrassing. They're always wanting to increase yield."4

This focus on quantity over quality has come at a steep nutritional cost. The tomato, for instance, has seen some of the largest nutrient declines — losing a quarter of its calcium and more than half of its vitamins.

•The quest for eternal shelf life — Perhaps the most egregious example of sacrificing nutrition for commercial gain is the development of the "long shelf life" tomato. In the 1970s and 1980s, Israeli researchers created a hybrid tomato that decays much more slowly after being picked.

While this innovation reduced waste and revolutionized the global tomato market, it came with serious downsides. As Haim Rabinowitch, professor emeritus at The Hebrew University of Jerusalem, one of the developers, admits:5

"The genes for ripening inhibition carry with them some negative traits. For instance, flavor deteriorates and we [have] less nutrients. But I didn't know because we never measured it. Only later in the '90s and the early 2000s, we started looking into the quality traits. I offered a project like that to many seed companies. I even gave it a name. I called it ‘ACE’ tomato.

Why ACE? Vitamins A, C and E, and I said it will be much healthier tomato. We don't have it in supermarkets, this variety. The industries, they don't care."The Nutrient Gap: Heirloom vs Hybrid
In a revealing experiment, the filmmakers compared a modern hybrid tomato to an heirloom variety. The results were stark:

After one week, the heirloom tomato showed signs of decay and was no longer fit for sale. The hybrid looked unchanged.
After two weeks, the heirloom was moldy. The hybrid still appeared fresh.
It took 25 days for the hybrid to become unsellable — extending shelf life from three days to over three weeks.
But this longevity comes at a steep price. When tasted, the hybrid was described as "tasteless" compared to the flavorful heirloom. To quantify the nutrient differences, the documentary team had both tomatoes analyzed in an accredited laboratory. The results were eye-opening:6

"The hybrid tomato contains a significantly lower level of the five nutrients analyzed. It contains 63% less calcium, 29% less magnesium, and 72% less vitamin C. The levels of lycopene and polyphenols, two antioxidants that help fight cardiovascular diseases, are two times lower in the hybrid than in the farmer's variety tomato."

This data provides clear evidence that the push for longer shelf life and higher yields has dramatically reduced the nutritional value of our produce.

The Global Seed Oligopoly
As the documentary reveals, the push for hybrid seeds is being driven by a handful of multinational corporations that dominate the global seed market. Just four companies — Bayer (formerly Monsanto), Corteva (formerly DuPont), Syngenta and Limagrain — control two-thirds of all seeds sold worldwide.7,8 This concentration of power has serious implications:

1.Loss of biodiversity — As uniform hybrid varieties replace traditional seeds, we're losing genetic diversity at an alarming rate. The Food and Agriculture Organization (FAO) of the United Nations reports that 75% of global agrobiodiversity has been lost due to the adoption of "improved" varieties.9

2.Farmer dependence — Hybrid seeds don't reproduce true-to-type, forcing farmers to buy new seeds each year. This creates a cycle of dependence on seed companies.

3.Skyrocketing seed prices — The documentary reveals that some tomato seed varieties now sell for up to $450,000 per kilogram — more than double the price of gold.10

4.Exploitative labor practices — To keep costs down, seed production is often outsourced to developing countries where child labor and below-minimum wage payments are common.

The Dark Side of Seed Production
The widespread use of child labor in hybrid seed production is featured in the documentary. In India's Karnataka state, a major hub for vegetable seed production, researchers found that 10% of workers in seed fields are children under 14 — despite laws prohibiting child labor.11 Why are children employed? As Davuluri Venkateswarlu, author of "Soiled Seeds," a report on the issue, explains:12

"The hybridization activity is very, very delicate. It requires a lot of skills. The children are preferred because they can do these repetitive activities very faster than adults, and also they are more obedient. Two children can do the work of three adults. That is the kind of calculation farmers have."

Even adult workers face exploitation. Women working in tomato seed fields earn just $2.80 per day — 40% below India's legal minimum wage. Yet these seeds will sell for tens of thousands of dollars per kilogram in Europe and North America.

This exploitation persists because multinational seed companies turn a blind eye to the practices of their local subcontractors. When confronted, they hide behind vague statements about "promoting decent working conditions" without taking concrete action.

The Health Implications
The health implications of this nutrient collapse in our food supply are immense. While the full impact is still being studied, we can draw some alarming conclusions:

1.Increased risk of nutrient deficiencies — As fruits and vegetables contain fewer vitamins and minerals, it becomes harder to meet your nutritional needs through diet alone. This may contribute to the rise in deficiencies we're seeing, particularly in minerals like magnesium and trace elements.

2.Reduced antioxidant intake — The dramatic drop in vitamin C, lycopene and polyphenols means we're getting far fewer protective antioxidants from our produce. This could increase vulnerability to oxidative stress and related chronic diseases.

3.Link to rising chronic disease — While many factors contribute to the increase in chronic diseases like heart disease and diabetes, the depletion of protective nutrients in our food supply plays a role.

4.Hidden hunger — Even people eating what appears to be a healthy diet rich in fruits and vegetables are getting far fewer nutrients than they realize. This "hidden hunger" has wide-ranging health effects.

5.Increased reliance on supplements — As food becomes less nutritious, more people will turn to dietary supplements to meet their nutritional needs. While supplements have their place, they're not a perfect replacement for nutrients obtained from whole foods.

The Path Forward: Reclaiming Our Food
The situation seems dire, but there are rays of hope. Around the world, farmers, researchers and citizens are working to preserve agricultural biodiversity and promote more nutritious food production. Here are some key initiatives:

•Seed banks and exchanges — Organizations like Kokopelli in France are working to preserve heirloom and traditional seed varieties. Their "Seeds Without Borders" program distributes these seeds to farmers and gardeners worldwide, helping to maintain genetic diversity.

As noted in the documentary, "By conserving these endangered seeds, we are taking back the choice to plant or eat non-standardized fruit and vegetables which are the best produce for both our planet and our health."13 Supporting these seed preservation efforts is crucial for maintaining biodiversity and giving farmers alternatives to hybrid seeds.

•Regenerative agriculture — Farming practices that focus on building healthy soils increase the nutrient content of crops. By moving away from chemical-intensive methods and embracing techniques like cover cropping, composting and diverse crop rotations, we can produce more nutritious food while improving environmental health.

•Consumer awareness and demand — As consumers become more aware of the nutrient issue, they can drive change through their purchasing decisions. Choosing heirloom varieties, supporting local farmers using diverse seed stocks and demanding more transparent labeling all make a difference.

•Policy changes — At a broader level, we need policies that incentivize farming practices that enhance soil health and nutrient uptake, protect farmers' rights to save and exchange seeds, and enforce fair labor practices in seed production globally.

How to Protect Your Nutrient Intake and Support a More Nutritious Food System
The loss of nutrients in our food supply is a silent crisis that demands urgent attention. By understanding the problem and taking action — both in our personal choices and by advocating for systemic change — we can work toward a future where our food nourishes us as nature intended.

The path to truly healthy food isn't through further industrialization or genetic modification. Instead, we must look to the wisdom of traditional farming methods, embrace biodiversity and prioritize nutrient density. Our health, and the health of future generations, depends on it. To protect your health and support a more nutritious food system, consider:

Choosing heirloom and open-pollinated varieties when possible — These often have higher nutrient levels and better flavor than hybrid varieties.

Supporting local farmers and farmers markets — Small-scale producers are more likely to grow diverse, nutrient-dense crops.

Grow your own — Even a small garden or a few containers provide incredibly nutritious produce.

Opt for organic — While not a guarantee of higher nutrients, organic produce is less likely to contain harmful pesticide residues.

Eat a diverse diet — Don't rely on just a few fruits and vegetables — incorporate a wide variety to ensure you're getting a broad spectrum of nutrients.

Consider targeted supplementation — While whole foods should be the foundation of your diet, high-quality supplements can help fill nutrient gaps.

Support organizations working to preserve seed diversity and promote sustainable agriculture.

Stay informed and spread awareness — Share this information with friends and family to help drive change."

Sources and References
1 YouTube, Moconomy, Industry Scandal: The Loss of Nutrients July 20, 2024, 1:12
2, 4 YouTube, Moconomy, Industry Scandal: The Loss of Nutrients July 20, 2024, 1:53
3 J Am Coll Nutr. 2004 Dec;23(6):669-82. doi: 10.1080/07315724.2004.10719409
5 YouTube, Moconomy, Industry Scandal: The Loss of Nutrients July 20, 2024, 13:10
6 YouTube, Moconomy, Industry Scandal: The Loss of Nutrients July 20, 2024, 20:57
7 Equal Exchange Center, From Alternative Trade to Corporate Consolidation
8 YouTube, Moconomy, Industry Scandal: The Loss of Nutrients July 20, 2024, 43:08
9 FAO.org, What Is Happening to Agrobiodiversity?
10 YouTube, Moconomy, Industry Scandal: The Loss of Nutrients July 20, 2024, 26:47
11 YouTube, Moconomy, Industry Scandal: The Loss of Nutrients July 20, 2024, 27:59
12 YouTube, Moconomy, Industry Scandal: The Loss of Nutrients July 20, 2024, 33:04
13 YouTube, Moconomy, Industry Scandal: The Loss of Nutrients July 20, 2024, 49:06

[grapevine]

The Muscle Growth Doctor: Exercise At Night Is A Terrible Idea! Grip Strength = Disease! Andy Galpin

Source: https://youtube.com/watch?v=hQ78Hpwrt80

(2:28:37)
Dr Andy Galpin, PhD, is Professor of Kinesiology (the study of movement) at California State University, Fullerton. He is the Co-Director of the Center for Sport Performance and Founder/Director of the Biochemistry and Molecular Exercise Physiology Laboratory.

00:00 Intro
02:49 Enhancing People's Physical & Cognitive Performance
04:54 Why You Care About Human Performance?
10:37 What's Your Academic Background
11:36 What's the Range of People That Come to You & What Do They Want Fixing?
14:21 What Stops Us from Reaching Our Optimal Performance?
20:51 How Vitamin Deficiencies Affect Our Body
24:35 Why We Don't Get Accurate Results from Blood Tests
28:20 You Need to Understand Why Your Body Markers Are Down
32:23 Why People Struggle to Sleep
37:21 How to Improve Your Sleep
42:57 Is 8h the Optimal Sleep Time?
48:32 The Misconceptions of Sleep Debt
50:49 The Power of Doing Tasks at Your Usual Circadian Times
55:02 Environmental Factors That Affect Our Sleep
01:04:55 Create the Optimal Environment for Restorative Sleep
01:06:34 Sleep Debt
01:09:50 How to Stop Travels Disrupting Your Sleep
01:12:06 How Important Is Your Heart Rate Variability (HRV)?
01:13:33 The Impact of Keto Diet and Carbs on Your HRV?
01:16:16 The Effects of Introducing Carbs Back into Your Diet
01:18:20 How to Have a Healthy HRV?
01:23:15 Good Morning Routines for Improved HRV
01:27:52 Does Red Light Have an Effect on Our Bodies?
01:30:14 The Importance of Choosing the Right Training Exercises
01:31:08 Gain Muscle Mass and Stay Lean
01:34:57 When to Eat When Exercising
01:36:56 Best Training for Best & Lasting Performance
01:39:00 The Death Dangers of Falling at 60+ Years Old
01:42:09 What Is VO2 Max?
01:44:41 What VO2 Max Says About Your Health
01:49:11 People Don't Believe Their Health Problems Can Be Fixed
01:52:02 The Exercise and Steps to Improve VO2 Max
01:54:21 To Build Muscle You Need to Add Variations to Your Exercise Routine
01:58:31 Creatine Benefits for Your Body
02:03:47 Fat Loss
02:11:08 Depriving Yourself from Food Isn't Beneficial in Weight Loss
02:12:12 Why Should You Do Strength Before Endurance?
02:12:36 How Technology Will Shape Our Health
02:18:18 The Impact of Minimizing Stressors in Our Lives
02:24:21 Last Guest Question

[onawah]

Dimethyl Sulfoxide (DMSO): Benefits, Uses and Side Effects

Posted by onawah (here)
Dimethyl Sulfoxide (DMSO): Benefits, Uses and Side Effects
by Dr. Joseph Mercola
November 08, 2024
https://articles.mercola.com/sites/a...&rid=158368727

https://media.mercola.com/ImageServe...ffects-pdf.pdf

Source: https://youtube.com/watch?v=QGhd21VaYv4

"Story at-a-glance
DMSO is an organosulfur compound used as a topical pain reliever and anti-inflammatory agent. It activates cellular stress responses at low to moderate levels, boosting resilience against future threats
Research shows DMSO inhibits cancer cell growth and triggers apoptosis in various cancer cell lines, suggesting promise as a targeted therapy for slowing or stopping cancer progression
In a mouse model of Alzheimer's, low-dose DMSO improved visual function, likely due to its antioxidant properties. It may be useful as an early intervention in neurodegenerative diseases
DMSO is related to MSM, which has shown benefits for joint health. It also exhibits antibacterial properties, inhibiting growth of various bacterial strains at relatively low concentrations
While promising, DMSO has side effects including garlic-like odor and skin irritation. It increases absorption of other substances and may interact with certain medications, necessitating caution in its use
You may have heard of dimethyl sulfoxide (DMSO), an organosulfur compound, as a remedy for joint pain or inflammation. DMSO is produced both naturally and synthetically. It's found in trace amounts in certain foods and widely used as a solvent in scientific research and industrial processes due to its ability to dissolve organic compounds.

In medicine, DMSO is used as a topical pain reliever and anti-inflammatory agent. It’s approved by the U.S. Food and Drug Administration for the treatment of interstitial cystitis, also known as bladder pain syndrome, a chronic condition that causes bladder pain, pressure and discomfort.1

DMSO is also used as a cryoprotectant to prevent cell damage during freezing.2 This compound shows promise for benefitting many health conditions, but it has a complex relationship with your cells. Recent research on yeast cells, for instance, reveals that DMSO's effects depend heavily on concentration and exposure time, influencing whether the compound is healing or harmful.3

DMSO: A Cellular Stressor That Builds Resilience
At low and moderate levels, DMSO activates cellular stress responses that boost your resilience. However, at higher concentrations or with prolonged exposure, it impairs cell growth and may even prove toxic. Too little DMSO didn't trigger the response, while too much overwhelmed the cells' defenses.

The key lies in how DMSO interacts with cell membranes and energy production. Short-term exposure to moderate DMSO levels didn't significantly damage yeast cell membranes or reduce their metabolic activity.4 But it did trigger stress response genes, priming cells to better handle future threats, explaining some of DMSO's protective effects.

The study found that DMSO activated yeast cells' environmental stress response (ESR) program at certain concentrations. This cellular alarm system, triggered by various mild stresses, prepares cells to better handle future, potentially more severe challenges.

It's a bit like how exercise stresses your body in the short term but ultimately makes you stronger. This stress response activation helps explain why DMSO is helpful in cryopreservation or as a protective agent against radiation damage.

At higher doses though, DMSO began to interfere with cell division and survival. Your cells' preferred energy source plays a surprisingly important role in how well they tolerate DMSO. The study found that yeast cells using primarily aerobic respiration, which relies heavily on oxygen, were most sensitive to DMSO's toxic effects. In contrast, cells using fermentation or a mix of fermentation and respiration fared better.

This difference likely stems from how DMSO interacts with mitochondria, your cell's power plants. Cells with highly active mitochondria are more vulnerable to factors that disrupt their delicate balance, including DMSO at higher doses. The compound may destabilize mitochondrial membranes, leading to increased production of harmful reactive oxygen species (ROS).

The researchers found that lowering oxygen levels in the yeast's environment increased their DMSO tolerance across the board. This suggests that DMSO's effects are closely tied to oxygen-dependent processes in your cells.

An Ally in the Fight Against Cancer
Studies reveal DMSO has another unexpected benefit: fighting cancer. Researchers investigated DMSO's impact on both leukemia cells (representing blood cancers) and epithelial cancer cells (representing solid tumors).5 They found that DMSO significantly inhibited cell growth in all tested cancer cell lines, including MV4-11 and TF-1a leukemia cells, as well as Hep-G2 liver cancer cells and MCF7 breast cancer cells.

This inhibition was both dose and time-dependent, with noticeable effects starting at concentrations as low as 2% DMSO. At 10% DMSO, growth inhibition reached up to 69% in some cell lines after 72 hours of exposure. This suggests DMSO could be used as a targeted therapy to slow down or stop cancer growth.

The study didn't just stop at observing growth inhibition — it explored how DMSO affects cancer cells. Using a trypan blue assay, which distinguishes between live and dead cells, the researchers found that 5% DMSO increased cell death rates from about 2% to 3% to 15% to 19% in leukemia cells after 48 hours. This indicates that DMSO isn't just slowing cancer cell division; it's actively killing these harmful cells.6

Under the microscope, DMSO-treated cancer cells showed significant changes in morphology. The cells shrank, their density decreased and, most importantly, their nuclei began to fragment. These nuclear fragments, visible as multiple dots within nondividing cells, are a hallmark of apoptosis, or programmed cell death.

The higher the DMSO concentration, the more pronounced these effects became. Even the adherent epithelial cancer cells, which normally form a smooth monolayer in culture, began to detach and cluster when exposed to DMSO. These observations suggest that DMSO could be triggering the cancer cells' built-in self-destruct mechanisms.

DMSO Activates Cancer Cells' Self-Destruct Sequence
Digging deeper into the molecular mechanisms, the researchers uncovered how DMSO sets off a cascade of events leading to cancer cell death. They found that DMSO significantly decreased levels of CDK2 and cyclin A — crucial proteins that regulate cell division. The CDK2-cyclin A complex, which plays a key role in driving cells from one phase of the cell cycle to the next, was particularly affected.7

By disrupting these regulators, DMSO effectively puts the brakes on cancer cell proliferation. But perhaps most tellingly, DMSO triggered DNA fragmentation in the treated cancer cells. This is considered a definitive sign of apoptosis, as it represents the cell systematically destroying its own genetic material. The researchers confirmed this by detecting increased levels of activated caspase 3, an enzyme central to the execution of apoptosis.

Interestingly, they didn't see activation of caspase 9, suggesting that DMSO triggers apoptosis through the extrinsic pathway rather than the intrinsic mitochondrial pathway. This specific mechanism could be crucial in developing targeted cancer therapies that don't harm healthy cells.

The study suggests that even at relatively low concentrations, DMSO has profound effects on cancer cell health and survival. Moreover, because DMSO is already widely used and well-tolerated in many medical contexts, it could potentially be fast-tracked for cancer treatment studies.

DMSO Improves Visual Function in Alzheimer's Model
Early animal studies raised some concerns about DMSO causing eye problems, particularly affecting the lens. These findings were not found to translate to humans,8 however, and recent research offers a more reassuring perspective for those considering DMSO as part of their health regimen.

Research using a mouse model of Alzheimer's revealed that DMSO, even at very low concentrations, significantly improves visual function.9 The study focused on 5xFAD mice, which are genetically engineered to develop Alzheimer's-like symptoms. These mice typically experience a decline in contrast sensitivity, an important aspect of vision that's also affected in human Alzheimer's patients.

Remarkably, when treated with just .01% DMSO in their drinking water, the mice showed a marked improvement in their contrast sensitivity. This improvement was comparable to the effects seen with R-carvedilol, a drug specifically being investigated for Alzheimer's treatment.

The fact that such a low dose of DMSO could produce these benefits is particularly intriguing, as it suggests DMSO's therapeutic effects may have been underestimated in previous research where it was used merely as a vehicle for other drugs.

Early Intervention Potential with DMSO
The study's findings point to DMSO's antioxidant properties as a mechanism for its beneficial effects. DMSO is well-known as a powerful scavenger of hydroxyl free radicals, which contribute to oxidative stress, a factor in the development and progression of Alzheimer's disease. The researchers observed that DMSO treatment corrected abnormalities in the retina that are associated with oxidative stress.

Specifically, they found that DMSO normalized the thickness of a particular layer in the retina (the ELM-RPE layer) that becomes contracted in the presence of oxidative stress. This correction suggests that DMSO is actively combating oxidative damage in the retinal tissue. Given that your retina is essentially an extension of your brain, these findings imply that DMSO could be providing similar protective effects throughout the central nervous system.

This is particularly exciting because oxidative stress is believed to be one of the earliest events in the development of Alzheimer's, occurring even before the appearance of characteristic amyloid plaques and tau tangles.

Given these findings, there’s potential for DMSO as an early intervention in Alzheimer's disease. The study focused on relatively young mice (4 months old) that were just beginning to show signs of visual impairment.10 The fact that DMSO was able to improve function at this early stage suggests it could be particularly valuable as a preventative measure or early treatment.

Early intervention is crucial in Alzheimer's disease, as by the time cognitive symptoms become apparent, significant brain damage has often already occurred. If DMSO can help protect against oxidative stress and maintain neuronal health from the earliest stages of the disease process, it could slow or even prevent the progression to full-blown Alzheimer's.

Moreover, the safety profile of DMSO at low doses is well-established, making it an attractive option for long-term use in at-risk individuals.

Beyond the Brain: DMSO's Wider Implications
While this study focused on visual function and retinal health, its implications reach far beyond Alzheimer's disease. The protective effects of DMSO observed in the retina extend to other tissues and organs throughout your body. Oxidative stress is implicated in a wide range of age-related conditions, from cardiovascular disease to arthritis.

For instance, DMSO is closely related to another compound that could benefit your joint health: methylsulfonylmethane (MSM). DMSO is a precursor to MSM, and both compounds share similar sulfur-based structures. Like DMSO, MSM has been shown to have significant anti-inflammatory effects, especially for joint pain. A randomized, double-blind, placebo-controlled trial in Japan explored the effects of MSM on mild knee joint pain in healthy individuals.11

Participants who took 2 grams of MSM daily for 12 weeks experienced significant improvements in their knee health compared to those taking a placebo. The study used a comprehensive measure of knee health (the Japanese Knee Osteoarthritis Measure) and found that MSM not only improved knee-specific symptoms but also enhanced overall health conditions.

This research suggests the sulfur-containing compounds in both DMSO and MSM may offer a range of health benefits, from neuroprotection to joint pain relief.

Given that DMSO can be converted to MSM in your body, using DMSO might provide some of the joint health benefits associated with MSM, in addition to its neuroprotective effects and anti-inflammatory and pain-relieving properties. These actions make DMSO an intriguing compound for overall health maintenance as you age.

DMSO's ability to inhibit and kill a range of bacteria — even at low concentrations — has also been known for decades. Researchers tested DMSO against several bacterial strains, including Staphylococcus aureus, β-hemolytic streptococci, Corynebacterium acnes, Escherichia coli and Proteus species.12

They found that a 20% concentration of DMSO was enough to inhibit the growth of all these bacteria. So, even at relatively low concentrations, DMSO can effectively stop bacterial reproduction.

DMSO Risks, Dosing Suggestions and Other Considerations
While DMSO shows promising benefits, it's important to approach its use with caution and awareness. As with any supplement or treatment, DMSO has side effects and contraindications that you need to be aware of. The most common side effect is a garlic-like taste or breath odor, which occurs because DMSO breaks down into dimethyl sulfide in your body. Some people may also experience skin irritation when DMSO is applied topically.

DMSO also increases the absorption of other substances through your skin, amplifying the effects of medications. This means you need to be careful about what comes into contact with your skin when using DMSO topically. It's also important to note that DMSO interacts with certain medications, including blood thinners and steroids.

Additionally, high concentrations may cause liver damage if used improperly. Pregnant women and those with liver disease should use caution when considering DMSO. As always, I recommend consulting with a holistic health care practitioner to determine if DMSO is right for you.

Proper product selection and dosing are key to getting the best results. A Midwestern Doctor recommends looking for DMSO that has at least 99.9% purity and, if liquid, is stored in glass. For topical dosing, start with 70% and dilute it 50/50 with water. Gradually work your way up to the full-strength product as long as no skin irritation occurs. You can also progress to a 100% DMSO product if you have thick scars or are using it for specific health conditions.

For oral dosage, a typical starting dose is 0.5 to 1 teaspoon (of 70% or 100%). You may gradually increase the dose as long as you are tolerating it well. The maximum safe dosage is up for debate, but generally 3 teaspoons is considered the upper limit. Keep in mind that since DMSO has an unpleasant taste, you’ll likely want to mix it with milk or juice when consuming it orally. Be sure to mix it well so the DMSO doesn’t settle at the bottom.

Remember, while DMSO shows promise, it's not a miracle cure. It should be considered as part of a holistic approach to health, including a nutrient-dense diet, regular exercise, stress management and other lifestyle factors that support your overall well-being. Used responsibly and under proper guidance, DMSO could be a valuable tool in your health arsenal, particularly for its antioxidant, neuroprotective, anticancer and anti-inflammatory properties."

Sources and References
1 Mayo Clinic, Dimethyl sulfoxide
2 National Library of Medicine, PubChem, Dimethyl Sulfoxide
3, 4 Scientific Reports volume 14, Article number: 21974 (2024)
5, 6, 7 Journal of Medical Discovery 2020; 5(4)
8 Arch Ophthalmol. 1968;79(4):423-427. doi: 10.1001/archopht.1968.03850040425011
9, 10 Acta Neuropathol Commun. 2024 May 31;12:85
11 Nutrients. 2023 Jun 30;15(13):2995. doi: 10.3390/nu15132995
12 JAMA. 1965;193(11):923-928. doi: 10.1001/jama.1965.03090110061015

[meat suit]

Posted by meat suit (here)
DMSO sounds very interesting, I have never tried it.
I have an ongoing shoulder/arm issue that might benefit.
Does anybody have a recommendation for a UK available brand ?

Update🤙😁
So, bought 70/30 dmso/aloe vera gel and the book.
Within 10 days of application to my shoulder/arm I am back to nearly normal function and very little remaining pain.
This stuff is amazing. Nothing else I tried over many months has initiated so much healing for this issue.
I could feel it working from the first application.
Wow

[Mike]

I've been taking cacao recently and it is nothing short of remarkable

[Bill Ryan]

Posted by Mike (here)
I've been taking cacao recently and it is nothing short of remarkable

Mike, can you say more? Do you mean raw cacao, the basic ingredient of chocolate, with nothing else added? Assuming so, how do you take it, and how much, and what benefits do you experience?

(Raw cacao is available everywhere in Ecuador. I make wonderful home-made chocolate from it with added coconut oil and honey, nothing else. )

[onawah]

I've been using raw organic cacao powder for a long time,and it has really helped me with my chocolate addiction.
(I eat organic as much as possible, but organic chocolate bars are expensive and always contain sugar (or some kind of unhealthy substitute).
What I do instead is use raw, organic cacao powder to make hot chocolate (but not too hot), cake frosting or fudge sauce with soft butter, cream or sour cream, raw honey, and a pinch of salt.
Heated slighly (not too much or it destroys the nutrients in raw cacao and honey), it makes a great fudge sauce to serve over ice cream.
I add vanilla just before eating, but not when I make up the mixture, otherwise it makes for an unpleasant chemical reaction.
Raw cacao powder is a health food, whereas heat-treated cacao, which is what usually happens to it when it's made into commercial products, is not.
Another great inexpensive health food is raw Maca powder.
See: https://projectavalon.net/forum4/sho...=1#post1065843

[Sirus]

Posted by Bill Ryan (here)

Posted by Mike (here)
I've been taking cacao recently and it is nothing short of remarkable

Mike, can you say more? Do you mean raw cacao, the basic ingredient of chocolate, with nothing else added? Assuming so, how do you take it, and how much, and what benefits do you experience?

(Raw cacao is available everywhere in Ecuador. I make wonderful home-made chocolate from it with added coconut oil and honey, nothing else. )

Please share your recipe

[Bill Ryan]

Posted by Sirus (here)
Please share your recipe

Ha. A bunch of cacao, and some dollops of honey and coconut oil. It's different every time, and I just dip my finger in it to check it's sweet but not too sweet.

I melt it all in a pan, which takes just a few minutes. Then I pour it into a soup dish, which goes into the freezer to set. I sometimes add chia seeds, raisins, nuts, chopped dates, or anything else that comes to hand. It's better than anything I've ever bought commercially.

This is the end product:

[Mike]

Posted by Bill Ryan (here)

Posted by Mike (here)
I've been taking cacao recently and it is nothing short of remarkable

Mike, can you say more? Do you mean raw cacao, the basic ingredient of chocolate, with nothing else added? Assuming so, how do you take it, and how much, and what benefits do you experience?

(Raw cacao is available everywhere in Ecuador. I make wonderful home-made chocolate from it with added coconut oil and honey, nothing else. )

Sure no prob.

It's organic cacao powder, no sweeteners added (not to be confused with cocoa). I mix it in a full fat yogurt with brewers yeast, creatine, and collagen, and it's been like rocket fuel. Even on it's own it has almost the same effect. I've taken countless supplements over the years and this one stands alone. It's really something else.

I take 2 doses a day. Each dose = 1 tablespoon.

Even the best supplements I've used over the years only allowed a painfully slow crawl up the ladder to health, one rung at a time. This stuff has shot me miles up the ladder in one go, and I can actually see some daylight and possibilities.

As I've mentioned many times over the years, I've really been struggling with this mitochondrial heart stuff. I saw a study that involved a group of people suffering from mitochondrial heart failure that took cacao over the course of 3 months and nearly totally recovered. I'm pretty jaded now, but that made an impression on me. I noticed a difference on only my second dose. My heart feels more relaxed, I breathe easier, I think faster and clearer, and my overall endurance has improved significantly. I'm excited to see where I'll be in 3 months. I'll keep everyone filled in on my progress.

P.S. that cacao chocolate you make sounds delicious!

[meat suit]

This is the rescent Joe Rogan podcast with Mel Gibson.
The mention the 'brica'? Thing at about 137.00, a fat loss thing..
Does anybody know what that is?

Source: https://youtube.com/watch?v=1rYtrS5IbrQ

[Bill Ryan]

Posted by meat suit (here)
This is the rescent Joe Rogan podcast with Mel Gibson.
The mention the 'brica'? Thing at about 137.00, a fat loss thing..
Does anybody know what that is?

Source: https://youtube.com/watch?v=1rYtrS5IbrQ

~~~

He's referring to health coach Gary Brecka.

https://www.garybrecka.com

[meat suit]

Thank you😁

[onawah]

Raw cacao generates stem cells

Or click here: https://www.youtube.com/shorts/9A6BiqKoW8o

The HEALTHIEST POWDER for Your Body and Overall Health! Dr. Mandell
motivationaldoc
9.58M subscribers
Dec 19, 2023

"Cacao is extremely high in antioxidants, which help protect your cells from oxidation and aging. Raw cacao contains more than 20x’s the amount of antioxidants in blueberries (ORAC value score). It's packed with flavonoids. These nutrients have been shown to help lower blood pressure and improve blood flow to the brain and heart.
Cacao improves circulation and hydration in the skin. Circulation stimulates new blood flow to the surface of the skin, keeping it healthy and glowing
Cacao is a potent anti-inflammatory, it soothes redness and blemishes, improving the skin’s complexion.
Cacao has high amounts of iron and magnesium and is the richest food source of these nutrients."

Source: https://youtube.com/watch?v=4PmXyZM_Y-o

Posted by onawah (here)
I've been using raw organic cacao powder for a long time,and it has really helped me with my chocolate addiction.
(I eat organic as much as possible, but organic chocolate bars are expensive and always contain sugar (or some kind of unhealthy substitute).
What I do instead is use raw, organic cacao powder to make hot chocolate (but not too hot), cake frosting or fudge sauce with soft butter, cream or sour cream, raw honey, and a pinch of salt.
Heated slighly (not too much or it destroys the nutrients in raw cacao and honey), it makes a great fudge sauce to serve over ice cream.
I add vanilla just before eating, but not when I make up the mixture, otherwise it makes for an unpleasant chemical reaction.
Raw cacao powder is a health food, whereas heat-treated cacao, which is what usually happens to it when it's made into commercial products, is not.
Another great inexpensive health food is raw Maca powder.
See: https://projectavalon.net/forum4/sho...=1#post1065843

[onawah]

Fiber Found in Everyday Foods Helps Remove Forever Chemicals from Your Body
Analysis by Dr. Joseph Mercola
July 17, 2025
https://articles.mercola.com/sites/a...&rid=341963886

https://media.mercola.com/ImageServe...micals-pdf.pdf

Source: https://youtube.com/watch?v=LG5vr3N4t7E

"Story at-a-glance
A specific type of fiber called beta-glucan, found in oats and barley, was shown to reduce levels of harmful PFAS chemicals in the blood within just four weeks
Participants who consumed beta-glucan experienced significant drops in legacy PFAS compounds like PFOA and PFOS, which are linked to cancer and hormone disruption
The fiber group was the only one to show a meaningful reduction in the seven most high-risk PFAS chemicals identified by the National Academies of Sciences, including those that raise your risk for thyroid disease, cancer and ulcerative colitis
In a follow-up study using mice, animals exposed to high PFAS levels but fed beta-glucan had lower blood PFAS, improved fat metabolism and less liver stress compared to controls
The key to beta-glucan’s effect is its gel-forming action in your gut, which traps PFAS and interrupts their reabsorption cycle, allowing your body to eliminate them through stool

Most people have no idea they're carrying around a hidden chemical load that their bodies weren't designed to handle. But the reality is, we're living in a world saturated with per- and polyfluoroalkyl substances, commonly known as PFAS. These synthetic compounds are engineered to resist heat, water and oil — and they don't just stay on the surface.

Once these substances enter your bloodstream, they're incredibly hard to get rid of. That's why researchers are searching for real, practical solutions. Many believe that detoxing PFAS is a lost cause — that once they're in your body, they're in for good. But new evidence suggests otherwise.

It turns out your gut, not your liver or kidneys, is one key to turning this around. And the solution doesn't involve harsh protocols or extreme diets. It starts with something as simple as how you digest your food — and whether the right kind of fiber is present to help carry these chemicals out.

If you've ever wondered why you're dealing with persistent fatigue, inflammation, hormone problems or chronic digestive issues, PFAS could be part of the story. These chemicals hijack your system slowly and silently. But there's now a realistic path to lowering that burden, and it starts by focusing on what's happening in your gut.

Source: https://youtube.com/watch?v=xOk45cs_99k

Four Weeks of Fiber Lowered Toxic PFAS in the Blood
A study published in Environmental Health evaluated 72 adult men with elevated LDL cholesterol who were already enrolled in a trial testing oat beta-glucan's effects on cholesterol.1

Beta-glucans are a type of soluble fiber found in oats and barley that form a gel-like substance in your gut, helping to trap and remove compounds like bile acids and, as this study explored, PFAS as well. PFAS chemicals, also known as "forever chemicals," are notoriously hard to remove from the body, so the researchers wanted to know: could a fiber intervention make a dent?

•Participants received either a fiber-rich supplement or a placebo for four weeks — All participants followed the original protocol, consuming either an oat beta-glucan drink (1 gram (g) of beta-glucan and 1.9 g total fiber per serving, three times daily) or a brown rice drink with no active fiber. Blood samples were collected at baseline and after four weeks to measure 17 different PFAS types.

•PFAS levels dropped significantly but only in the fiber group for legacy PFAS — While short-chain PFAS decreased in both groups, likely due to their shorter half-lives, the study found that only the group consuming beta-glucan showed significant reductions in long-chain PFAS known to persist for years in the body.

These included perfluorooctanoic acid (PFOA) and perfluorooctanesulfonate (PFOS) — two of the most studied PFAS compounds, both associated with increased cancer and hormone disruption risks.

•PFAS reductions occurred even in men with exposure levels typical of the general population — Researchers noted that all participants had detectable PFAS levels at the start of the study. The levels of certain PFAS were higher than previously reported in Canadian populations, suggesting rising background exposure. Despite this, the beta-glucan intervention still reduced PFAS levels, showing promise even for people without known occupational or high-dose environmental exposure.

•Only the fiber group saw a drop in the most concerning types of PFAS — These specific PFAS, identified by the U.S. National Academies of Sciences, Engineering, and Medicine (NASEM), are known to increase the risk for serious health issues like thyroid disease, kidney problems, ulcerative colitis and certain cancers.

If your blood level of these seven PFAS reaches just 2 nanograms per milliliter, doctors are advised to monitor your cholesterol, blood pressure during pregnancy and breast cancer risk. At 20 nanograms per milliliter, the recommendations expand to include regular screening for thyroid disease, testicular cancer and more. In the study, only the fiber group had a meaningful reduction in this high-risk PFAS group.

•The proposed mechanism is the fiber's ability to trap PFAS in your digestive tract — Researchers believe the gel-forming fiber worked because PFAS share biochemical properties with bile acids — compounds already known to bind to beta-glucan and get flushed out in feces. PFAS and bile acids are both amphipathic, meaning they have both water-loving and fat-loving parts. This allows them to interact with fiber gels and get excreted rather than reabsorbed.

Most PFAS don't leave your body easily. Once excreted into the bile, they're typically reabsorbed in your intestine, returning to your liver in a loop. Beta-glucan breaks this cycle by holding PFAS in your gut, giving your body a chance to eliminate them through stool rather than cycling them back into your bloodstream.

Oat Beta-Glucan Helped Mice Eliminate PFAS
In a related study published in Toxicology and Applied Pharmacology, researchers from Boston University used mice to examine whether oat beta-glucan could reduce the body's PFAS load.2 They exposed mice to a mixture of seven PFAS compounds in drinking water while feeding them diets that included either inulin, a non-gel-forming fiber, or oat beta-glucan — a gel-forming fiber.

•Despite drinking more contaminated water, fiber-fed mice had lower PFAS in their blood — The mice fed beta-glucan consumed more PFAS-contaminated water, yet ended up with lower blood levels of some of the most harmful PFAS. This suggests that the fiber helped block reabsorption of PFAS in the gut. In other words, even when these mice took in more of the toxic chemicals, their bodies were better at flushing them out before they could circulate back into the bloodstream.

•Mice on the fiber diet had better fat metabolism and lower liver fat — The beta-glucan-fed mice showed lower liver triglycerides and reduced fat accumulation in the small intestine and fat tissue overall. This matters because PFAS have been linked to metabolic disruption and fatty liver disease. These findings suggest that fiber offers a double benefit: lowering toxic load while improving fat regulation in the body.

•Fiber-fed mice experienced better lipid balance without triggering other stress responses — The researchers also looked at markers of liver stress and detoxification. A key enzyme linked to chemical detox was lower in the fiber-fed group during the cleansing phase, indicating that their bodies were under less toxic stress after PFAS exposure.

How to Reduce Your PFAS Burden with Targeted Fiber and Smarter Food Choices
If you're dealing with fatigue, hormone issues or unexplained weight gain, and you've already cleaned up your water, cookware and household products, you could be missing the last piece of the puzzle: what's stuck inside your body. PFAS aren't just external threats; they're internal ones too.

Once these forever chemicals get in, they linger for years unless you take direct steps to push them out. Here's where smart, gut-focused nutrition comes in. The right type of fiber, at the right time, makes a meaningful difference in your toxic load. But timing and your gut's condition matter. So, if you're trying to reduce PFAS levels in your system, start here:

1.Check your gut health first — If you regularly feel bloated after meals, go days without a bowel movement or have frequent loose stools, your gut likely isn't ready for high-fiber foods. Don't guess — listen to your symptoms. These are signs that your microbiome is imbalanced and your gut lining is inflamed or damaged. For now, avoid complex carbs and stick to simpler ones like fruit and white rice while your gut settles down.

2.Avoid fiber and fermentable carbs if your digestion is impaired — A damaged gut can't handle even "healthy" foods. Beans, leafy greens, cruciferous veggies and whole grains all ferment quickly and feed the wrong microbes when your gut is compromised. That drives more bloating, inflammation and gas. In this phase, you want fuel that doesn't backfire — whole fruit and cooked starches that digest cleanly without fermenting too fast.

3.Reintroduce fermentable fibers in small amounts once your gut calms — When your bloating stops and your digestion becomes regular, that's your green light. Start with resistant starches like cooked-and-cooled white potatoes or green bananas. These feed butyrate-producing bacteria — the kind that protect your gut lining and regulate inflammation. Slowly add in garlic, leeks and onions. Keep portions small and build up as your tolerance improves.

4.Eat foods high in beta-glucans once your gut is stable — Oats and barley contain beta-glucan, which binds to PFAS in your digestive tract and helps your body eliminate them through your stool. Once your digestion is in good shape, make this fiber part of your daily routine. Other good sources include organic rye, maitake and shiitake mushrooms, and seaweed like kombu.

Be mindful of your portions though, as most seaweeds contain polyunsaturated fats, including linoleic acid, which is harmful to your health in excessive amounts. Choose whole, minimally processed forms of beta-glucans whenever possible to get the most benefit.

5.Cut off PFAS exposure at the source — While you work to flush them out, don't let more in. Use a water filter certified for PFAS. Stop storing food in nonstick containers or wrappers. Replace your nonstick cookware with stainless steel, ceramic or enameled cast iron. Skip stain-resistant treatments on clothes and furniture. PFAS are everywhere, but the more you avoid them now, the less your body has to fight later.

FAQs About Removing PFAS with Fiber
Q: What are PFAS and why are they dangerous?

A: PFAS are synthetic chemicals used in nonstick cookware, food packaging, stain-resistant fabrics and firefighting foams. They build up in your blood, liver and fat tissues and don't easily break down. Long-term exposure has been linked to liver damage, hormone disruption, cancer, immune suppression and infertility.

Q: How do PFAS stay in my body for so long?

A: Once PFAS enter your system, usually through contaminated water or food, they're reabsorbed in your intestines and recirculated back to your liver in a loop. This recycling is what gives PFAS such long half-lives — many remain in your body for years unless that cycle is broken.

Q: Does fiber really help remove PFAS from my body?

A: Yes. Clinical research in humans and animals has shown that gel-forming fibers like oat beta-glucan bind PFAS in your gut and stop them from being reabsorbed. This allows your body to eliminate them through stool, reducing your overall PFAS burden over time.

Q: Should I add fiber to my diet immediately?

A: Not necessarily. If you have symptoms of gut dysfunction, like bloating, constipation, loose stools or food intolerances, you need to heal your gut first. Starting fiber too soon makes things worse. Begin with simple, low-fiber carbs like whole fruit or white rice, then reintroduce fiber slowly once your digestion stabilizes.

Q: What are the best ways to lower PFAS exposure and support detox?

A: Avoid sources of new PFAS exposure. Use PFAS-certified water filters, stop using nonstick cookware and stain-resistant products, and limit packaged foods. Once your gut is ready, include small amounts of beta-glucan-rich foods like organic oats or barley. Over time, this helps reduce PFAS levels while also improving your gut health and immune resilience."

+ Sources and References
1 Environmental Health March 15, 2025
2 Toxicology and Applied Pharmacology February 2025, Volume 495, 117188