The poisoning of America: Glyphosate, Statins and Vaccines

[onawah]

New Study Shows Glyphosate's Harmful Effect on Gut Bacteria
Even Low Levels of Glyphosate Alter Your Gut Microbiota
by Dr. Joseph Mercola
June 02, 2023
https://www.advancedbionutritionals....BoCb7MQAvD_BwE

https://media.mercola.com/ImageServe...obiota-pdf.pdf

"STORY AT-A-GLANCE
Gut microbiota composition was significantly impacted when mice were exposed to glyphosate at levels approximating the U.S. Acceptable Daily Intake of 1.75 mg/kg of body weight
Proinflammatory T cells and Lipocalin-2, a marker of intestinal inflammation, increased after low-dose glyphosate exposure
Low-dose glyphosate exposure also reduced the abundance of beneficial bacteria, including Bifidobacterium pseudolongum and Lactobacillus sp in the gut
Low levels of glyphosate also decreased microbial short-chain fatty acid (SCFA) biosynthesis pathways, an adverse effect, since SCFAs modulate gene expression, leading to increases in beneficial anti-inflammatory regulatory T cells
You can reduce your exposure to glyphosate by eating organic foods; saturating your body with glycine may help provide some protection from glyphosate toxicity

About 8.6 billion kilograms of glyphosate, equivalent to about 18.9 billion pounds, have been applied to agricultural fields and other land worldwide since 1974. The majority — up to two-thirds — was used in the last decade.1

Glyphosate is a key ingredient in herbicides like Roundup, which in its earlier days was advertised as "biodegradable" and "environmentally friendly." Monsanto even went so far as to claim it "left the soil clean" — until they were found guilty of false advertising because the chemical is actually dangerous to the environment.2

It’s toxic to humans, too, and is capable of altering gut microbiota, among other health risks. Perhaps most concerning of all, given that glyphosate has been widely detected in food and water, these changes occur even at low levels of exposure.

Low-Dose Exposure to Glyphosate Disrupts Gut Homeostasis
A team of University of Iowa researchers exposed mice to glyphosate at levels approximating the U.S. Acceptable Daily Intake of 1.75 mg/kg of body weight. When their fecal samples were analyzed, they found the exposure “significantly impacts gut microbiota composition,” including altering gut homeostasis. Proinflammatory T cells and Lipocalin-2, a marker of intestinal inflammation, increased after low-dose glyphosate exposure.3

Glyphosate kills plants by inhibiting the 5-enolpyruvylshikimate-3 phosphate synthase (EPSPS) enzyme. EPSPS is an enzymatic step in the shikimate pathway,4 which is involved in the synthesis of the essential aromatic amino acids phenylalanine, tyrosine and tryptophan.5

Since mammals do not have the shikimate pathway, it was suggested that glyphosate would not affect human health. However, some microorganisms do have the shikimate pathway, and it’s via this link that many of glyphosate’s adverse effects in humans may occur. According to the study:6

“Trillions of bacteria (gut microbiota) living in the human gut play a critical role in maintaining the healthy state of the human through the regulation of several host physiological processes, including the development and maintenance of the immune, endocrine, and nervous systems.

As bacteria utilize the shikimate pathway, glyphosate could alter gut microbiota composition by inhibiting gut bacteria harboring glyphosate sensitive EPSPS enzymes. Multiple in vitro studies have verified that many gut resident microbes are sensitive to glyphosate exposure.”

In addition to increasing fecal pH levels and proinflammatory markers, the study found low-dose glyphosate exposure reduced the abundance of beneficial bacteria, including Bifidobacterium pseudolongum and Lactobacillus sp. It also decreased microbial short-chain fatty acid (SCFA) biosynthesis pathways, an adverse effect, since SCFAs modulate gene expression, leading to increases in beneficial anti-inflammatory regulatory T cells.7

In short, the team explained, “We found that glyphosate exposure, at doses similar to the U.S. ADI, can alter gut microbiota composition and modulate the neuro-immune-endocrine system resulting in a proinflammatory environment.”8

Glyphosate May Disrupt Glycine Homeostasis


Source: https://www.bitchute.com/video/AXEAGQoUJ8o/


Stephanie Seneff, a senior research scientist at the Massachusetts Institute of Technology (MIT), has been studying glyphosate for years and has been a champion for helping to understand how and why glyphosate is so dangerous.

The increase in glyphosate usage in the U.S., as well as in Canada, is extremely well correlated with the concurrent increase in the incidence of multiple diseases, including breast cancer, pancreatic cancer, kidney cancer, thyroid cancer, liver cancer, bladder cancer and myeloid leukemia.9

Research scientist Anthony Samsel is one of Seneff’s co-authors, and together they’ve suggested that one of the ways glyphosate is harmful is via disruption of glycine homeostasis. Glyphosate has a glycine molecule as part of its structure (hence the “gly” in glyphosate). Glycine is a very common amino acid your body uses to make proteins.

Samsel and Seneff believe your body can substitute glyphosate and its metabolite aminomethylphosphonic acid (AMPA) into peptides and proteins, which results in damaged peptides and proteins being produced. According to Seneff as she explains in the video above:

“I believe that in certain proteins, in certain spots, glyphosate is able to get into the protein by mistake in place of the amino acid glycine. And to understand that glyphosate is a complete glycine molecule. It's a perfect match to glycine. Except that it has extra materials stuck onto its nitrogen atom.

… the protein that's going to recognize glycine in order to put it into DNA has to leave the nitrogen atom outside of its pocket because the nitrogen has to hook up with the next amino acid. So the fact that the nitrogen has some stuff on it doesn't matter to it. It says, ‘Oh, I have to fit exactly glycine very tightly.’

Glycine is the smallest amino acid. And in order to distinguish glycine from all the other amino acids all I need to do is make sure that I make a tiny space that fits only glycine …

Glyphosate will fit because it's a perfect glycine molecule. Except the nitrogen is sticking outside of that pocket so that it could hook. So the extra stuff on nitrogen is not constrained. This is important because I think a lot of people think, ‘Oh, it can't happen.’”

Going back to EPSPS, the bacterial version of EPSPS inserted into glyphosate-resistant Roundup Ready crop has alanine instead of glycine. But, according to Seneff, if you change the glycine into alanine by adding one extra methyl group, it ruins the protein.

“This is absolutely terrifying,” Seneff says. “They knew, ‘First we've got to get rid of glycine.’ And then that takes a hit on the enzyme. The enzyme doesn't work as well because it's got alanine there. It's got that extra methyl group that's in the way — the same problem that glyphosate causes.”

The arguments for why glyphosate specifically disrupts proteins that depend on glycine for phosphate binding are described more fully in a paper Seneff published together with colleagues arguing that glyphosate is a major factor in kidney failure among young agricultural workers in Central America.10


Source: https://www.bitchute.com/video/56u1O5hNAaEw/


Deuterium is a naturally occurring isotope of hydrogen. Provided your cell is healthy, it has deuterium-depleting enzymes and organelles that help remove deuterium from your cells. If your mitochondria are damaged by glyphosate, they're not going to be able to eliminate the deuterium properly. This is another way glyphosate contributes to chronic disease, Seneff says.

Your cells are surrounded by structured water, which is negatively charged and contributes to your body's energy production by supplying deuterium-depleted hydrogen to lysosomes and mitochondria. The structured water is maintained by sulfates, which makes sulfate extremely important for health.

Deuterium is everywhere, naturally, but your body has developed an intricate way to make it harmless by trapping it in the structured water, where it's beneficial, as it actually supports the creation of structured water.

Problems arise when you cannot make enough structured water to sequester it all. Then, the deuterium gets loose, causing mitochondrial dysfunction, impairing energy production and contributing to chronic disease.

Glyphosate, however, makes sulfate dysfunctional, which in turn destroys structured water, resulting in impaired energy production in the cell.11 The process is complex, but it’s important for understanding how and why glyphosate is such a pernicious and insidious toxin. Seneff explains more about deuterium and how glyphosate contributes to its buildup in your body in our video interview above.

Glyphosate Linked to Liver, Kidney Diseases
Since at least 2014, published papers have exposed a link between glyphosate exposure and chronic kidney disease of unknown etiology (CKDu) in Sri Lankan farmers.12 It’s been suggested that consumption of glyphosate-contaminated water may contribute to chronic kidney disease by facilitating the transport of heavy metals such as arsenic and cadmium into the kidneys.13

In 2019, researchers again named agricultural chemicals, including glyphosate and paraquat, as possible primary factors in CKDu, noting, “[G]lyphosate causes insidious harm through its action as an amino acid analogue of glycine, and … this interferes with natural protective mechanisms against other exposures.”14

A number of animal studies have linked glyphosate to liver damage as well, including one that dates back to 1979, which showed the chemical could disrupt mitochondria in rat livers.15

Glyphosate is also known to trigger the production of reactive oxygen species, leading to oxidative stress. As noted in Scientific Reports, “Elevation in oxidative stress markers is detected in rat liver and kidney after subchronic exposure to GBH [glyphosate-based herbicides] at the United States permitted glyphosate concentration of 700 μg/L in drinking water.”16,17

Researchers from King’s College London also showed an “ultra-low dose” of glyphosate-based herbicides was damaging in rats, leading to signs of non-alcoholic fatty liver disease.18 People living agricultural regions, like Salinas Valley, California, may be particularly at risk.

In a study of children in Salinas Valley, exposure to glyphosate and its degradation product aminomethylphosphonic acid (AMPA) was found to increase the risk of liver and cardiometabolic disorders in early adulthood, which could trigger the development of additional diseases later in life, including liver cancer, diabetes and heart disease.19

Glyphosate Is Virtually Everywhere — How to Avoid It
More than 80% of U.S. children and adults, ages 6 years and up, have detectable levels of glyphosate in their urine, according to data from the U.S. Centers for Disease Control and Prevention.20,21 Out of 2,310 urine samples that were collected as part of the National Health and Nutrition Examination Survey (NHANES), 1,885 contained glyphosate levels at or above the detection limit.

Even if you don’t live near an agricultural area or use glyphosate-containing herbicides in your garden, you’re likely being exposed via contaminated food and water. Fruits, fruit juices, vegetables, oatmeal and cereals are all likely sources of glyphosate in your diet.22

The use of glyphosate as a desiccant (drying agent) may be particularly problematic because it’s sprayed so near to harvest, which could result in higher residue levels and greater exposures to consumers.23 In 2020, food giant Kellogg announced they’re phasing out the use of glyphosate as a desiccant by 2025,24 but many other food manufacturers are still using this toxic chemical.

You can reduce your glyphosate exposure by primarily consuming organic foods. If you’re wondering what your levels are, HRI Labs has developed home test kits for both water and urine, available in my online store. I do not make a profit from the sale of these kits. I only provide them as a service of convenience.

The urine test kit reveals the amount of glyphosate you’ve been exposed to in the past two to three weeks, while the hair test shows accumulated exposure over the past three to four months.

If your levels are high, fermented foods, particularly kimchi, are potent chelators of these kinds of chemicals. Taking activated charcoal after a questionable meal can help bind and excrete chemicals as well. Remember to stay well-hydrated to facilitate the removal of toxins through your liver, kidneys and skin.

Glycine supplementation may also be a good option to help detoxify glyphosate, because to eliminate glyphosate, you need to saturate your body with glycine. Dr. Dietrich Klinghardt, who is a specialist in metal toxicity and its connection to chronic infections, recommends taking 1 teaspoon (4 grams) of glycine powder twice a day for a few weeks and then lowering the dose to one-fourth teaspoon (1 gram) twice a day.

This forces the glyphosate out of your system, allowing it to be eliminated through your urine. Considering glycine has additional benefits for longevity and disease prevention, this is a solid strategy for protection.

There are a wide variety of other uses for glycine, which is why I take about 15 grams every day, primarily with protein like eggs and beef as it rebalances the methionine to glycine ratio to decrease methionine’s negative impacts on your metabolism.

Additionally, you can use organic, grass-fed collagen, which is naturally rich in glycine. You can boost your collagen intake by making homemade bone broth using bones and connective tissue from grass-fed, organically raised animals, enjoying health benefits and helping reduce your glyphosate load at the same time."

+ Sources and References
1, 3, 4, 6, 7, 8 Environmental Toxicology and Pharmacology June 2023, Volume 100, 104149
2 BBC October 15, 2009
5, 9 Journal of Biological Physics and Chemistry January 2015, 15(3):121-159
10 Journal of Environmental Research and Public Health 2019, 16, 2734
11 Seneff and G Nigh. Sulfate’s Critical Role for Maintaining Exclusion Zone Water: Dietary Factors Leading to Deficiencies. Water 2019; 11: 22-42
12, 13 Int J Environ Res Public Health. 2014 Feb; 11(2): 2125–2147
14 Int J Environ Res Public Health. 2019 Jul 31;16(15). pii: E2734. doi: 10.3390/ijerph16152734
15 Environ. Contam. Toxicol. (1979) 22: 357
16, 18 Scientific Reports January 9, 2017
17 Environmental Toxicology and Pharmacology November 2012, Volume 34, Issue 3, Pages 811-818
19 Environmental Health Perspectives March 1, 2023
20 U.S. CDC, National Health and Nutrition Examination Survey, Glyphosate in Urine June 2022
21 Substack, Carey Gillam, UnSpun July 9, 2022
22 U.S. CDC, Diet Is a Factor in Contact With Glyphosate
23 Environmental Health News October 30, 2017
24 Kellogg’s Open for Breakfast

[Bill Ryan]

Bumping this thread with onawah's new post on the Poisoning the Food Supply thread:

~~~

Understanding Glyphosate's Growing Presence in Agriculture and Its Effects on Human Health

Analysis by Ashley Armstrong
January 28, 2025

https://articles.mercola.com/sites/a...an-health.aspx

https://media.mercola.com/ImageServe...health-pdf.pdf

(Bold letters my emphasis)

Story at-a-glance

• Glyphosate has become the most widely used herbicide in history, with usage increasing 100 to 300-fold since the late 1970s, resulting in its presence in 60% to 80% of the general population through food, water, and air exposure.
• Research has shown glyphosate can accumulate in the kidney, liver, colon, and brain, cross the blood-brain barrier, and has been found in human breast milk, indicating it doesn't simply get excreted as claimed.
• A two-year study found that exposure to Roundup (a glyphosate-based herbicide) at doses far below permissible levels caused organ damage and increased tumor incidence, particularly mammary tumors in female test subjects.
• Glyphosate has been identified as an endocrine disruptor, showing eight out of 10 key characteristics associated with endocrine-disrupting chemicals, and can affect future generations through epigenetic changes.
• Studies show switching to an organic diet can reduce urinary glyphosate levels by about 71% within six days, with the highest sources of exposure being conventional grains, processed foods, and the "Dirty Dozen" produce items.

A pesticide is any substance or mixture of substances designed to kill, repel, or control pests. Let’s break it down into the two components: The term "pest" refers to any organism (insects, weeds, rodents, fungi, bacteria, etc.) that is considered harmful or undesirable, particularly in agricultural settings. And then "-cide" is a suffix derived from the Latin word "caedere," meaning "to kill."

It is commonly used in words to indicate something that kills or destroys, such as herbicide (kills plants), insecticide (kills insects), and fungicide (kills fungi).

Pesticides serve as an umbrella term for substances targeting pests, with subcategories defined by the type of pest being addressed, such as herbicides for weeds, insecticides for insects, fungicides for fungi, and rodenticides for rodents.

There are natural options that can be highly effective in controlling pests, including neem oil, pyrethrins extracted from specific flowers, rotenone derived from plant roots, diatomaceous earth, Bacillus thuringiensis (a bacteria-based solution), sulfur, garlic and pepper extracts, and copper-based compounds. Many of these options are used in organic agriculture.

And then there are chemical agents. The types of synthetic pesticides commonly used in conventional agriculture include:

Pesticide category Main target Examples

• Insecticides Insects Cypermethrin, chlorpyrifos, malathion, imidacloprid, and the now banned DDT
• Herbicides Weeds Glyphosate, 2,4-D, atrazine, dicamba, paraquat, glufosinate
• Fungicides Fungi, molds and mildew Mancozeb, chlorothalonil, azoxystrobin, propiconazole
• Rodenticides Rodents like rats and mice Warfarin
• Nematicides Parasitic nematodes (roundworms) Fenamiphos, oxamyl, 1,3-dichloropropene
• Bactericides Bacteria Kasugamycin, streptomycin, oxytetracycline
• Miticides/acaricides Mites and ticks Abamectin, bifenazate, fenpyroximate

Waging chemical warfare against natural biological systems inevitably has consequences — Mother Nature will always prevail! While the widespread use of synthetic pesticides in global agriculture is driven by their ability to boost crop yields and produce cheap, abundant food.

This chemical-dependent farming system is deeply rooted in government policies and the profit-driven business models of Big Ag corporations.

Government subsidies, shaped by powerful agricultural lobbying, prioritize high-yield, chemical-intensive methods, which inadvertently fosters conditions that favor pesticide use, and favor chemical solutions over natural alternatives.

This system is further entrenched by the business model of major chemical corporations. These companies develop and patent pesticides, securing exclusive rights to their products for years. This monopolistic control allows them to command premium prices and substantial profits.

Their market power is further amplified by offering comprehensive agricultural packages that bundle pesticides with seeds and fertilizers, creating a cycle of dependency that reinforces their industry dominance.

It is important to keep this in mind when assessing mainstream messaging about the "safety" of glyphosate and other pesticide usage — of course they don’t want you to think these are bad since that is a threat to their business model!

Occasional pesticide use may not be that big of a deal, but our current agricultural system's heavy dependence on these chemicals has severe implications for both environmental and human health.

In this article, let’s focus on glyphosate and why we should be concerned that it dominates our agriculture system. (There are of course problems with other pesticides, too!). The evidence as a whole suggests we need to be cautious of our long-term exposure!

Source: https://youtube.com/watch?v=yMG2HvYaZls

So What Is Glyphosate?
Glyphosate is a synthetic, non-specific, systemic herbicide that kills many types of weeds and other vegetation by disrupting with the "shikimate pathway," a biochemical pathway that essential for plant survival. Since this pathway is absent in human cells, international "authorities" consider glyphosate to have no toxicity in humans. However, increasing evidence suggests otherwise.1

Glyphosate is the active ingredient in many herbicide products, including the popular "Roundup" product. These are referred to as glyphosate-based formulations (GBFs). GBFs unfortunately contain a range of other problematic chemicals in addition to glyphosate.2 GBFs are used in agriculture, commercial, industrial, and residential settings due to its broad-spectrum herbicidal properties.

The second most common use of glyphosate, after agriculture, is in landscape and turf management which include gardens, lawns, public spaces, parks, alongside roads and on golf courses.

In the grand scheme of things, glyphosate is still relatively "new." And it is a common trend in industry that many things aren’t officially labeled as a "health hazard" *until* they start causing major health problems, since there’s way too much money to be made by big businesses in the meantime! (Two examples include DDT and agent orange — which weren’t banned until they were proven to cause serious health problems). Science often lags industry!

So let’s recap briefly — In 1964, the patent was issued for use of glyphosate as a metal chelating and descaling agent to clean out mineral deposits in pipes and boilers. Then in 1971, glyphosate was patented as an herbicide after the discovery of its herbicidal properties.

In 1974, glyphosate was first sold to farmers by Monsanto, the company that was recently acquired by Bayer. Since the late 1970s, the use of glyphosate-based herbicides has increased between 100 to 300-fold!3

Glyphosate has become the most widely used chemical herbicide in history (for agriculture, commercial, industrial and residential settings) due to its broad-spectrum herbicidal properties. Tragically, this compound, which has been classified as a "probable carcinogen" by the International Agency for Research on Cancer,4 is now pervasive in our food, water, and air.

The surge in global pesticide use can be traced to a fundamental shift in agricultural practices — the transition to industrial farming, particularly through the advent of genetically engineered crops in the mid-1990s. These GMO crops were engineered with a specific purpose: to either produce their own insecticides or withstand powerful herbicides, or both.

Today, this technology dominates major crops, with approximately 94% of soybean production now using genetically engineered seeds designed to resist Monsanto-Bayer's glyphosate-based Roundup herbicide.

Before "Roundup Ready" crops, farmers had to carefully limit herbicide application to avoid damaging their crops. But with plants engineered to withstand glyphosate, farmers could spray more frequently and intensively. Between 1990 and 2014, glyphosate use exploded from 7.7 million pounds to 250 million pounds — a staggering 1,347% increase.

However, glyphosate's reach extends beyond just GMO agriculture through an unexpected practice: pre-harvest desiccation. So, Glyphosate isn’t just used to kill weeds — farmers have discovered they can use glyphosate as a drying agent on non-GMO crops, particularly in regions with short growing seasons and wet harvests. This "desiccation" practice involves spraying crops with glyphosate shortly before harvest to force uniform drying and enable earlier harvesting.

Originally developed in 1980s Scotland to address unreliable grain drying conditions, the technique has spread globally, leading to a 400% increase in glyphosate use on non-GMO wheat alone over the past two decades.5

"The herbicide, glyphosate, is applied to wheat crops before harvest to encourage ripening resulting in higher glyphosate residues in commercial wheat products within North America."6

Desiccation has now expanded to numerous crops including barley, oats, corn, lentils, beans, chickpeas, potatoes, millet, sugar beets and others. This widespread adoption of glyphosate, both in GMO cultivation and as a pre-harvest desiccant in non-GMO crops, helps explain why the global glyphosate market is projected to grow from $10.92 billion in 2024 to $11.89 billion in 2025, representing an 8.9% annual growth rate.

A common misconception is that "non-GMO" labeling equates to chemical-free farming. However, the "non-GMO" label only signifies that the crops have not been genetically modified; it does not address whether pesticides or herbicides were used during cultivation. In fact, pesticides are commonly applied to non-GMO crops.

It also unfortunately means we are being exposed to much higher levels than ever before, in the food we eat and in the feed consumed by livestock.

When animals consume grains and other feed crops treated with glyphosate, traces of the chemical can accumulate in their systems, ultimately resulting in higher levels of glyphosate residues in meat and dairy products, raising concerns about the potential health implications of chronic low-level glyphosate exposure throughout the food chain.

Health Consequences of Glyphosate
Now that we understand a little more of the backstory of glyphosate infiltration into the food system — what’s the big deal? Why should we care?

Monsanto originally claimed Roundup was safe based on a 90-day trial in rats. Well, one research group wanted to put this to the test and extend this 90-day trial to two years.7 The results are very concerning!

"Our study design was based on that of the Monsanto investigation in order to make the two experiments comparable, but we extended the period of observation from Monsanto's 90 days to 2 years. We also used three doses of GMOs (instead of Monsanto's two) and Roundup to determine treatment dose response, including any possible non-linear as well as linear effects.

This allowed us to follow in detail the potential health effects and their possible origins due to the direct or indirect consequences of the genetic modification itself in the NK603 GM maize, or due to the R herbicide formulation used on the GM maize (and not G alone), or both ...

We then also tested for the first time three doses (rather than the two usually employed in 90-day protocols) of the R-tolerant NK603 GM maize alone, the GM maize treated with R, and R alone at very low environmentally relevant doses, starting below the range of levels permitted by regulatory authorities in drinking water and in GM feed ...

Our findings show that the differences in multiple organ functional parameters seen from the consumption of NK603 GM maize for 90 days escalated over 2 years into severe organ damage in all types of test diets. This included the lowest dose of R administered (0.1 ppb, 50 ng/L G equivalent) of R formulation administered, which is well below permitted MRLs in both the USA (0.7 mg/L) and European Union (100 ng/L).

Surprisingly, there was also a clear trend in increased tumor incidence, especially mammary tumors in female animals, in a number of the treatment groups. Our data highlight the inadequacy of 90-day feeding studies and the need to conduct long-term (2 years) investigations to evaluate the life-long impact of GM food consumption and exposure to complete pesticide formulations."

There was organ damage when the study was extended to two years at a Roundup dose far below permissible levels in the U.S. and the E.U. Additionally, tumor incidence, particularly mammary tumors in females, increased in several treatment groups.

The results emphasize the inadequacy of short-term (90-day) studies and the importance of long-term research to fully assess the health risks of GM food and pesticide formulations. Unfortunately, there is currently no long-term data on the effects of glyphosate exposure in humans (this is pretty hard to accomplish in a well-controlled environment).

But does this mean we shouldn’t be concerned of the alarming data in animals? NO! Just because something doesn’t immediately kill you does not make it safe. Long term chronic exposure is a huge health threat.

And since glyphosate is present in 60% to 80% of the general population,8 we actually may be part of an ongoing, real-time experiment on its long-term health effects as we speak. Let’s dive in a little more to see what recent research says about the potential health concerns of glyphosate exposure. (There is plenty of evidence showing us it is not safe!)

Stored in the Body/Bioaccumulates
While many point to the fact that glyphosate is water soluble, so it is "easily excreted" by the body — they forget about these glyphosate-based-formulations where other ingredients are mixed in, such as surfactants.

Studies show accumulation in the kidney, liver and colon9,10,11 and in human biological fluids, representing a severe human health risk.

Studies also demonstrate that glyphosate can cross the blood-brain barrier and accumulate in the brain in a dose-dependent manner, increasing the risk of neurodegenerative diseases like Alzheimer’s.12

The presence of glyphosate in human breast milk13 is concerning for many health experts since it suggests that this chemical, despite being ‘water soluble, is accumulating in tissues and passing through biological barriers in ways that are not well understood!

Inflammation and DNA Damage
There are several studies documenting that it can induce inflammation and oxidative stress in various types of cells.14,15,16,17,18,19,20,21,22,23,24 As a result, glyphosate can increase DNA damage, significantly increasing cancer risks25,26,27,28,29 and kidney and liver dysfunction.30,31,32,33

Endocrine Disruption
Glyphosate has been shown to disrupt endocrine function34,35,36 and can lead to hormonal imbalances by influencing key hormonal pathways in the body.37,38

A 2020 review paper concluded that glyphosate exhibits eight out of 10 key characteristics associated with "endocrine disrupting chemicals," suggesting that glyphosate-based herbicides alter the biosynthesis of sex hormones.39

Roundup concentrations in the range of 10^3 times below the "MRL" can induce endocrine disturbances in human cells.40

Other alarming findings include that glyphosate can reduce sperm motility41,42 can interfere with protein synthesis, which can suppress spermatogenesis and cell growth,43 and decrease serum testosterone in young male rats.44

Impacts Next Generation Through Epigenetics
There is also data demonstrating that glyphosate not only impacts an individual’s health but also impacts the health of their descendants through epigenetic changes by interfering with normal methylation processes and gene expression.45,46

Perinatal exposure to low doses of glyphosate formulations impaired female reproductive performance and induced fetal growth retardation and structural congenital anomalies in mammal F2 offspring.47

Exposure to glyphosate at doses deemed "safe" for human health during gestation significantly increased anogenital distance (AGD) in both male and female rat pups. AGD is the measurement between the anus and the genitalia and is often used as a biological marker in toxicology and reproductive studies to assess the effects of endocrine-disrupting chemicals.

Changes in AGD, particularly during development, can indicate hormonal imbalances or disruptions caused by environmental exposures, such as pesticides or other chemicals. Additionally, treatment with Roundup delayed the onset of first estrus and was associated with elevated serum testosterone levels in adult rats.48

Disrupts Gut Health
Regulatory agencies claim glyphosate is harmless to humans because we don’t have the shikimate pathway that glyphosate targets. Well, the microbes in our gut contain this pathway! Oops! Humans are made up of approximately 30 trillion human cells and about 39 trillion microbial cells, meaning the microbes in our gut slightly outnumber our human cells.

Glyphosate targets the shikimate pathway by inhibiting the activity of a key enzyme in this pathway, 3-phosphoshikimate 1-carboxyvinyltransferase (EPSPS), which is present in many of the microbes in our gut, disrupting gut health and throwing off our natural gut balance.

Glyphosate-sensitive Class I EPSPS enzymes are found in all bacteria, but its impact varies significantly among species. The Human Microbiome Project found that 732 out of 941 bacteria species in our gut have at least one copy of the gene that glyphosate targets. This means that 55% of our gut bacteria are sensitive to glyphosate, 38% are resistant, and 7% are unclassified.49



"Commensal bacteria (the ‘good guys’) appear to be more susceptible to glyphosate, as they are more likely to possess glyphosate-sensitive Class I EPSPS enzymes than potentially pathogenic bacteria, thereby promoting dysbiosis."

Beneficial bacteria are more likely to possess Class I EPSPS enzymes which makes them susceptible to dying off, and opportunistic pathogens in the gut are more likely to possess glyphosate-resistant Class II EPSPS enzymes, allowing them to thrive under glyphosate exposure.

In other words — glyphosate hinders the growth of beneficial gut bacteria while promoting the growth of pathogenic bacteria, leading to dysbiosis.

"Glyphosate residues on food could cause dysbiosis, given that opportunistic pathogens are more resistant to glyphosate compared to commensal bacteria.50

Here, we evaluate the literature surrounding glyphosate’s effects on the gut microbiome and conclude that glyphosate residues on food could cause dysbiosis, given that opportunistic pathogens are more resistant to glyphosate compared to commensal bacteria."51



Glyphosate is designed to kill weeds and microorganisms in the soil, but our digestive systems contain trillions of microorganisms. So yes, glyphosate and glyphosate-based-herbicides negatively impact gut health52,53,54 by inducing inflammation55 and causing dysbiosis.

This has negative systemic implications since gut health impacts the whole body including mood, brain function, and immunity. And unfortunately, this gut impact wasn’t really considered when the "safe" human intake standards were created.

Scientists frequently discuss how the negative gut impacts are not considered when "regulatory agencies" set the "acceptable daily intake" (ADI), which is determined by dividing the no-observed-effect-level (NOEL) by a safety factor.

"However, only direct glyphosate toxicity was considered when determining the NOEL. Alarmingly, glyphosate’s influence over health through secondary means, such as the gut microbiome, was never considered. Given that the gut microbiome is critical for our overall health and disease susceptibility, glyphosate residues on wheat may contribute to dysbiosis, thereby affecting our overall health."56

Compounding Impacts
Research suggests that the health risks associated with glyphosate exposure are even more pronounced when it comes to glyphosate-based herbicides (GBHs), or "Glyphosate-Based-Formulations (GBFs)," rather than pure glyphosate,57,58,59 likely due to the cumulative toxic effects of the additional chemicals involved.

While pure glyphosate is used in some cases, it is typically found as part of a GBH/GBF, where it is combined with other ingredients to enhance its ability to penetrate plant tissues more effectively.

For example — it has been shown that Roundup is more toxic than glyphosate alone.60 Roundup includes the co-formulant polyethoxylated tallow amine (POEA) which has been demonstrated to have toxic effects.61,62

The issue is further complicated by the proprietary nature of most of these GBHs/GBFs, where the ingredients and their relative proportions remain undisclosed. This lack of transparency poses a significant challenge for researchers, who are left in the dark about the specific components, their quantities, and the potential synergistic effects when these chemicals interact.

Adding to the concern, crops are often treated with a "cocktail" of agrochemicals in industrial ag, including other herbicides alongside GBHs. For example, research has shown that glyphosate’s cytotoxic effects can intensify when combined with other herbicides, such as Paraquat.63 This synergistic interaction suggests that even low levels of glyphosate residues in our food supply could have serious health consequences when combined with other widely used agrochemicals.

Alarmingly, this synergistic phenomenon has never been thoroughly studied, leaving a critical gap in our understanding of the full risks posed by these chemical concoctions.

Highest Sources
Glyphosate enters the human body through inhalation, ingestion, or contaminated food.64 And as a systemic herbicide, it is deeply absorbed by plants and moves throughout, including the roots, stems, and fruits. This means glyphosate cannot be washed off produce and isn’t broken down by cooking or heating.65,66

So, the best strategy is to reduce exposure through mindful food sourcing when you can. Processed foods are the most likely source of glyphosate contamination, making it another compelling reason to reduce or eliminate their consumption!

Studies consistently show that switching to an organic diet (since glyphosate is not allowed in organic agriculture) or choosing foods that are tested to be low in glyphosate, dramatically reduce glyphosate levels in the body.67,68 In one study, an organic diet intervention reduced urinary glyphosate levels by 70.93% and its main metabolite AMPA by 76.71% within six days.69 A diet higher in organic food is also associated with a reduced risk of cancer.70

When it comes to grains, choosing organic (or knowing a chemical free, regeneratively grown source) is essential. Grains, including wheat, corn, soy, rice, oats, and beans, often contain the highest concentrations of pesticides since many are genetically modified (and thus sprayed throughout the season), and non-GMO grains are frequently desiccated with glyphosate-based-herbicides before harvest, which increases pesticide residue.

The Environmental Working Group (EWG) routinely tests food for pesticides, and one of the highest sources tested are a common breakfast staple in many homes: Quaker Oatmeal Squares (since the oats are likely desiccated right before harvest).71 A light glyphosate bath on your breakfast cereal — yum!

For produce, aim to buy organic whenever possible, but try to prioritize sourcing organic for the "Dirty Dozen" to reduce your pesticide exposure — the 12 fruits and vegetables with the highest pesticide residues, according to the EWG’s 2024 report,72 include strawberries, spinach, kale, collard greens, mustard greens, grapes, peaches, pears, nectarines, apples, peppers, cherries, blueberries, and lettuce.

When it comes to meat, eggs, and dairy, if you are buying these at the grocery store — organic is the best choice. Glyphosate accumulates in eggs73,74,75,76 and glyphosate is present in the meat of cattle and in the urine of cows that consume contaminated food.77

But better yet is getting to know your local farmer. Not all farmers can afford the organic certification process, but many are committed to sustainable, chemical-free practices. And "organic" is not required for something to be chemical free. Instead, know your farmer and ask about their farming practices!

Supporting these farmers and farm cooperatives is a great way to make a positive impact on your health, the agricultural system as a whole, and the environment.

Conclusion
Regulatory agencies establish "tolerable limits" for glyphosate, but these limits overlook potential long-term and cumulative effects, fueling concerns about its safety in animal feed and the broader food chain. While some food samples may fall below the U.S. Environmental Protection Agency’s (EPA) "allowable daily intake" (ADI) of 1.75 mg per kg of body weight, critics argue that this threshold is fundamentally flawed.

Plus, why is the U.S. limit nearly six times higher than the European Union’s ADI of 0.3 mg per kg? Why does such a significant disparity exist?

The ADI fails to account for recent evidence linking glyphosate to probable carcinogenicity, its pervasive presence in food and water, the evidence of severe gut disruption, and its potential role as an endocrine disruptor, which could affect hormone levels differently across various stages of human development.

Additionally, safety tests were based only on isolated glyphosate, ignoring the compounded toxicity of commercial formulations containing other harmful chemicals. Compounding the risk, glyphosate residues from multiple food sources accumulate, amplifying exposure day to day.

In conclusion, the widespread presence of glyphosate in our bodies, combined with regulatory gaps and the herbicide’s persistent nature in food, calls for urgent action. By being more mindful of our food choices, we can take meaningful steps to reduce exposure and protect our health from the potential long-term effects of this pervasive chemical.

Supporting food systems that do not rely on toxic pesticides is a crucial step toward shifting agriculture from the bottom up. You can make a difference by supporting organic and regenerative farmers.

Think of it as voting with your fork (or spoon) — you're essentially voting against the chemical-based conventional farming system!

Real, lasting change will likely not come from the top down, as Big Ag continues to profit from harmful practices. By empowering and supporting sustainable, pesticide-free farming, we can create a healthier future for future generations to come."

About the Author
Ashley Armstrong is passionate about helping others restore metabolic health and in creating an alternative food system low in PUFAs and low in toxic agrochemicals like glyphosate.

Armstrong is the co-founder of Angel Acres Egg Club, which specializes in low-PUFA (polyunsaturated fat) eggs that are shipped to all 50 states. Recent laboratory testing has confirmed that Angel Acres eggs are completely free of glyphosate!

This achievement reflects a commitment to quality and a unique partnership with row crop farmers who practice regenerative agriculture practices to produce the low-PUFA chicken feed ingredients and do not use agrochemicals.

Armstrong also co-founded Nourish Food Club, which ships low-PUFA chicken, low-PUFA pork, beef, cheese, A2 dairy and traditional sourdough to all 50 states. While the egg club has memberships open, Nourish Food Club has a temporary waiting list.

- Sources and References
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2 Mass.gov, Glyphosate Scientific Review Revised Draft Phase 2 Report
3 North Dakota State University of Agriculture and Applied Science, March 2018, Pre-harvest Glyphosate Timing in Oats and Final Oat Quality
4 WHO, International Agency for Research on Cancer, March 20, 2015
5 The Healthy Home Economist, The Real Reason Wheat Is Toxic (it’s not the gluten)
6, 50, 51, 56 Front Microbiol. 2020 Sep 25;11:556729
7, 40 Environ Sci Eur. 2014 Jun 24;26(1):14
8 J. Verbr. Lebensm. 10, 3–12 (2015)
9 Front. Toxicol., September 18, 2024, Sec. Regulatory Toxicology, Volume 6
10 Journal of Immunotoxicology, 17(1), 163–174
12 J Neuroinflammation 19, 193 (2022), Abstract
13 Moms Across America, April 7, 2014
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16 Toxicology. 2017 Jul 15:387:67-80
17 Environ Int. 2020 Feb:135:105414
18, 30 Environ Toxicol Pharmacol. 2009 Nov;28(3):379-85
19, 31 Environ Health. 2015 Aug 25:14:70
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21, 33 Front Immunol. 2014 Oct 7:5:491
22 Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18581-6
23 Toxicology. 2014 Nov 5:325:42-51
25 International Agency for Research on Cancer, Some Organophosphate Insecticides and Herbicides
26 J Epidemiol Community Health. 2016 Aug;70(8):741-5
27 Leuk Lymphoma. 2002 May;43(5):1043-9
28 Food Chem Toxicol. 2018 Oct:120:510-522
29 Exp Mol Med. 2015 Aug 28;47(8):e179
34 3 Biotech. 2018 Oct;8(10):438
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36 Vet Anim Sci. 2020 Jun 24:10:100126
37, 59 Front Endocrinol (Lausanne). 2021 Mar 15;12:627210
38 Beyond Pesticides, November 25, 2022
39 U.S. Right to Know, November 13, 2020
41 Toxics. 2017 Dec 21;6(1):2
42 Int J Environ Res Public Health. 2018 May 30;15(6):1117
43 ACS Omega. 2021 Jun 2;6(23):14848–14857
44 CDC, Agency for Toxic Substances and Disease Registry, Glyphosate
45 Toxicol In Vitro. 2020 Mar:63:104736
46 Front Endocrinol (Lausanne). 2021 May 21:12:671991
47 Arch Toxicol. 2018 Aug;92(8):2629-2643
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53 Interdiscip Toxicol. 2013 Dec;6(4):159–184
55 Ecotoxicol Environ Saf. 2020 Jan 15:187:109846
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64, 66 Sustainability 2018, 10(4), 950
65 Int J Hyg Environ Health. 2012 Nov;215(6):570-6
67 EWG, August 11, 2020
68 Environmental Health News, August 11, 2020
69 Environ Res. 2020 Oct:189:109898
70 JAMA Intern Med. 2018;178(12):1597-1606
71 EWG, October 24, 2018
72 EWG, The Dirty Dozen™
73 The Alliance for Natural Health USA, April 19, 2016
74 Sci Rep. 2020 Apr 14;10(1):6349
75 Sci Rep. 2021 Sep 29;11:19290
76 SciELO, Food Sci. Technol 37 (3), July-Sept 2017
77 J Environ Anal Toxicol 2014, 4:2

"https://articles.mercola.com/sites/articles/archive/2025/01/28/glyphosate-agriculture-human-health.aspx?ui=8d3c7e22a03f5300d2e3338a0f080d2da3add85bca35e09236649153e4675f72&sd=20110604&cid_sour ce=dnl&cid_medium=email&cid_content=art1ReadMore&cid=20250128&foDate=true&mid=DM1695055&rid=21511412 9

Also see: Dr. Stephanie Seneff – HOW GLYPHOSATE DESTROYS YOUR GUT
https://projectavalon.net/forum4/sho...=1#post1330468

[Ravenlocke]

The Solari Report | Catherine Austin Fitts

How's That for the Old Switcheroo!


https://x.com/solari_the/status/2024661939624751260

[Ravenlocke]

Thomas Massie


This week I will introduce the “No Immunity for Glyphosate Act” to undo the recent Executive Order which promotes glyphosate (Round-Up) and insulates manufacturers from liability. #MAHA

https://x.com/RepThomasMassie/status...64921816830409

HealthRanger
@HealthRanger
·
16h
Ask yourself why they spray glyphosate on WHEAT products when there's no such thing as glyphosate-resistant (GMO) wheat.

They spray it AFTER the crop is done growing. They spray it as a drying agent.

So no, glyphosate doesn't grow wheat. It doesn't do anything other than poison the food supply and cause cancer and microbiome depletion, hormonal problems, infertility, critical mineral depletion and other toxic effects.

Glyphosate is derived from nerve agent chemical weapons and shares elements of the same organophosphate molecular structure.


https://x.com/HealthRanger/status/2024743076334326186

[Ravenlocke]

Tom Renz

🚨🚨🚨Breaking - Is THIS why the administration is fighting so hard to protect cancer-causing glyphosate?

Bayer Pharmaceuticals has worked with both Ballard Partners and Mercury LLC. Susie Wiles, the President’s Chief of Staff, was a lobbyist for both companies and Pfizer. Pam Bondi was a lobbyist at Ballard Partners. This is profoundly important in understanding why the Administration would take such an unpopular position on an issue so important to MAHA in an election season.

Trump’s CoS, Susie Wiles, and Pam Bondi both worked for Ballard Partners; Wiles was a managing partner at Mercury. It appears their lobbying didn’t end when they took their positions with the administration.

BTW - for anyone still failing to understand the EO and effective immunity, it is important to note that by calling glyphosate a national security concern and stating that the Sec of Ag should ensure they do not “endanger the corporate viability” of glyphosate producers, the Administration is providing new defenses and demonstrating that the DOJ will continue to fight against liability for people sickened by these poisons. Bondi has already submitted documents to the SCOTUS attempting to block liability in the glyphosate cases.
@HealthRanger

@VigilantFox

https://x.com/RenzTom/status/2026405497210024220

https://x.com/RenzTom/status/2026461356254261752

https://x.com/RenzTom/status/2026526613286859059

[Ravenlocke]

HealthRanger

Pam Bondi's DOJ is arguing for glyphosate immunity in federal court

https://x.com/HealthRanger/status/2026340690922197419

[sdv]

Weeds develop 'immunity' to herbicides, or at the very least, you have to keep spraying because every few months they will pop up again.vOne of the best ways to keep weeds away is to physically pull them from the ground, with roots. Really!

Pesticides? Bees are needed for pollination. Many of the wildlife that is needed to grow healthy plants get killed along with the 'pests'. I live in a large agricultural valley. A lot of farmers are now growing crops in a controlled environment (literally covering large fields with net), whoch is protection against pests. Bee hives are brought in for pollination.

Artificial fertilizer results in unnaturally large fruit and vegetables, which are not as tasty. (Actually all of these practises result in less tasty produce so more use of artificial flavourants in canned and preserved goods.)

Humanity has gotten itself into a cycle of artificiality in the production of food, which not only results in profitability for some but survival of an entire industry of production and supply chains dedicated to controlling politics, survival and obscene enrichment for a few 'at the top'.

Geez, there are enough natural dangers for humans to contend with on this planet. That our own species would be poisoning us through food, water and medicines is obscene. A related current scandal:

The National Consumer Commission has launched an inquiry in the wake of a study by the University of the Free State on potentially harmful chemicals in sanitary pads and liners.

The endocrine-disrupting chemicals are linked to health complications such as hormonal imbalance, infertility, endometriosis, and cancer. Millions of South African women and girls use these products monthly.
https://www.timeslive.co.za/news/sou...search-report/

[Ravenlocke]

Andrew Kaufman MD
@AndrewKaufmanMD
·
Feb 26
Are these moves MAHA?

Cheap drug deals that push Ozempic?
Glyphosate being sprayed on our food?
Do you support wearable technology and AI doctors?

Many people are still under the two-party spell and believe that Trump and RFK Jr. are working for the health of Americans while every move they make is in service to the pharmaceutical companies and chemical companies.

It’s time to leave the old system behind and that means no more trusting experts or three-letter agencies for your health.

It’s time to be your own health authority.

Andrew Kaufman MD

Feb 26
Are these moves MAHA?

Cheap drug deals that push Ozempic?
Glyphosate being sprayed on our food?
Do you support wearable technology and AI doctors?

Many people are still under the two-party spell and believe that Trump and RFK Jr. are working for the health of Americans while every move they make is in service to the pharmaceutical companies and chemical companies.

It’s time to leave the old system behind and that means no more trusting experts or three-letter agencies for your health.

It’s time to be your own health authority.

Start here:

https://x.com/AndrewKaufmanMD/status...60591290507697

[Ravenlocke]

Andrew Kaufman MD

Feb 23
When I was working in psychiatry and I started to taper children off of their psych meds, the group that fought me the hardest was the teachers.

They were afraid of these children, and mistakenly feared that taking them off meds would cause violence and upheaval. I had to tolerate being lectured by the facility administration more than once, but I carried on with my mission.
Well, in the end, I was completely vindicated.

It turned out that the teenagers I worked with didn’t become more violent, but less so.
I’ve watched lives change in powerful ways.

With more awareness and intentional changes, I’ve seen people gain better control over their behavior, sleep more deeply, and feel more balanced overall. Their physical health improved too and many patients actually lost weight, built strength, and felt more energized in their bodies.
Mental balance doesn’t come from adding more drugs.

It comes from addressing the root causes like stress, lifestyle, trauma, and environment.

Join me for a free masterclass this month where I’ll dive into the truth about psych meds and how you can taper off without harming yourself.

I am going to help you break the cycle you’re in so you can liberate yourself and heal without having to rely on harmful interventions.

https://x.com/AndrewKaufmanMD/status...01702193602928