Transduction and Modern Illnesses: Can "Wild" Strains Gene Swap with "Tamed" Ones? (Autism.)

[Tesla_WTC_Solution]

Scientific Expose

Tesla: I found an old NIH paper this morning while writing this post, hypothesizing that a sub-acute tetanus infection may account for symptoms of autism. Please read this thread and tell me what you think about the idea, and why the NIH left it as a mere hypothesis instead of proving it to be true themselves.

When the story came out a year or two ago regarding German E. Coli strains testing positive for Yersinia Pestis genes, I should have been a little more concerned about people understanding what this means. People were hospitalized, and didn't some of them die?

http://en.wikipedia.org/wiki/Transduction_(genetics)

Transduction is the process by which DNA is transferred from one bacterium to another by a virus.[1] It also refers to the process whereby foreign DNA is introduced into another cell via a viral vector. Transduction does not require physical contact between the cell donating the DNA and the cell receiving the DNA (which occurs in conjugation), and it is DNAase resistant (transformation is susceptible to DNAase). Transduction is a common tool used by molecular biologists to stably introduce a foreign gene into a host cell's genome.

I became interested in transduction (without knowing the word for it, actually) because of research done by my ex-boyfriend. He worked extensively with other scientists in a multi-national effort to develop more effective viral vectors for swapping genes in bacterial DNA.

Just before the outbreak of Black Plague-tainted E. Coli, traced to and blamed on German farms, I had emailed this man in hopes of him explaining whether or not he was aware of the possibility that his technology would enable gene swapping in the wild, in situations outside the laboratory, with potential to affect the quality of life of innocent human beings.

I never did hear back from him on whether or not his technology was capable of altering the natural flora present in the human intestines. I would imagine that my question was disturbing, if not well-timed. Within weeks of my correspondence, I heard about the outbreak of Y. Pestis-laced E. Coli in Germany.

http://socioecohistory.wordpress.com...onized-e-coli/

Germany’s E.Coli SuperBug Found To Contain Bubonic Plague DNA! Is the World Facing Genetically Modified, Weaponized E. Coli?

Dr. Rima Reports: Weaponized e. Coli Found to Contain Plague DNA
They tell us the “Super bug E. coli 0104:H” is terrorizing Germany, causing otherwise healthy people to develop Hemolytic-Uremic Syndrome (HUS) in which their kidneys fail, their red blood cells explode and then, tragically, they die.
…
E. coli is found in the guts of every mammal and is generally harmless. In fact, it is present in massive quantities: half of the volume of the normal bowel excretion is made up of their huge numbers. But when a good germ goes wrong, it can cause disease in the host or anyone who picks it up through contamination or lack of hygiene.
-
And E. coli 0104:H4 has gone very, very wrong, with, it would appear, quite a bit of help from its friends. Mike Adams, the intrepid Health Ranger, revealed to the English speaking world that this extraordinarily aggressive E. coli (from a family of bugs which are normally passive and non-aggressive in the extreme) had been systematically genetically altered through laboratory manipulation, to be totally resistant to 8 classes of antibiotics.
-
Natural News Article Link: http://www.naturalnews.com/032623_ec...egetables.html
….
Helge Karch, the director of the Robert Koch Institute (Germany’s CDC). who heads a consulting laboratory at the Münster University Hospital in Germany says that he has discovered that the super killer contains DNA from E. coli, which is what he expected. It also contains (unexpectedly for those who don’t expect such genocidal manipulations) DNA from the organism that causes plague, responsible for wiping out a quarter of Europe’s population during the Black Death (1348-1351).

You guys ask about psychic experiences a lot on Avalon. Well, I emailed my European friend about this research within months of the Germany outbreak. Within two weeks of the outbreak, I had published an article showing how Y. Pestis and E. Coli are commonly used in the lab and that the target of some viral vector development projects was being able to swap specific genes between the two diseases. The blog was taken offline many months later for unrelated reasons.

Yersinia Pestis
Escheria Coli
Clostridia
Clostridium Tetani

Transduction and ability to alter gut flora in children

Since we know now that E Coli and Bubonic plague can gene swap, what about Clostridium? Is it possible that getting a Tetanus shot after being exposed to other Clostridium strains might enable a dangerous gene swap, putting tetanus toxin genes into another strain of Clostridia harbored in the gut?

Would doctors know what to look for, or even expect to find low levels of toxins normally produced by a Tetanus infection and not Difficile?

Is there a link between Tetanus vaccine and abnormal gut flora in kids?

Clostridia

http://treatautism.ca/biomedical-tre...a-and-viruses/

Research by Dr. Sidney Finegold compared the gut flora of children with regressive ASD to neurotypical children. The results show that clostridial counts were higher in the children with autism. The number of clostridial species found in the stools of children with ASD was greater than in the stools of neurotypical children. Children with ASD had 9 species of Clostridium not found in the neurotypical group. The neurotypical group showed only 3 species not found in children with autism. In all, there were 25 different clostridial species found. In stomach and small intestine specimens, the most striking finding was total absence of Clostridia from neurotypical children and significant numbers of such bacteria from children with autism.

These studies demonstrate significant alterations in the upper and lower intestinal flora of children with late-onset ASD and may provide insights into the nature of this disorder.

Research by Dr. Derrick McFabe, at the University of Western Ontario, has explored aquired Clostridia infection and it’s relation to autism spectrum disorder. In his study, rodents injected with propionic acid (from Clostridial species) displayed autism like behaviours including:

Spinning
Repetitive behaviours
Seizures / convulsions
Pushing away
Hyperactivity
Altered social interaction and impairment in “play” like behaviour

Here are some ways that Clostridia could play a role in autism:

Too much Clostridia
Impaired immune activity
Damage to digestive tract
Nutrient deficiencies
Inflammation
Diet

http://en.wikipedia.org/wiki/Tetanus

Tetanus (from Ancient Greek: τέτανος tetanos “taut”, and τείνειν teinein "to stretch") is a medical condition characterized by a prolonged contraction of skeletal muscle fibers.[1] The primary symptoms are caused by tetanospasmin, a neurotoxin produced by the Gram-positive, rod-shaped, obligate anaerobic bacterium Clostridium tetani.[2]

Infection generally occurs through wound contamination and often involves a cut or deep puncture wound. As the infection progresses, muscle spasms develop in the jaw (thus the name "lockjaw") and elsewhere in the body.[2] Infection can be prevented by proper immunization or post-exposure prophylaxis.[3]

Can Clostridia genes be swapped using a virus? YES.

http://microbewiki.kenyon.edu/index....ni_and_Tetanus

The origin of the plasmid pE88 is still unclear. Over 50% of the ORFs on the plasmid are unique to C. tetani (Brüggemann 2003). Toxin genes are currently—or were in their evolutionary history—part of a flexible clostridial gene pool. Many of the toxin genes in pathogenic Clostridium species are on plasmids or capable of transduction by phages (Brüggemann 2005).

C. botulinum, which produces various forms of the botulinum neurotoxin (BoNT), has been shown to transfer its toxin-encoding plasmid by conjugation. In one study, a tagged BoNT-encoding plasmid was transferred from one strain of C. botulinum to another. Bacteriophages for transduction were not observed, and gene transfer was not inhibited by DNase, ruling out transformation of free-floating DNA (Marshall 2010). The epsilon-toxin plasmids in C. perfringens Type D have also been shown to be transferable to other cells by conjugation (Hughes 2007). Given this evidence, and the fact TeTx is quite similar to BoNT, it seems highly probable that the TeTx plasmid was acquired via some form of horizontal gene transfer, though it has clearly undergone its own divergent evolution since that point.

So they've known this since 2005 and we still get tetanus shots whether or not Clostridia is in our guts.

"Transduction is especially important because it explains one mechanism by which antibiotic drugs become ineffective due to the transfer of antibiotic-resistance genes between bacteria."

What does the NIH say about a link between autism and tetanus?
Wait, it's still a hypothesis because the NIH doesn't really want to know what causes autism symptoms.

http://www.ncbi.nlm.nih.gov/pubmed/9881820

Med Hypotheses. 1998 Aug;51(2):133-44.
Autism and Clostridium tetani.
Bolte ER.

Abstract
Autism is a severe developmental disability believed to have multiple etiologies. This paper outlines the possibility of a subacute, chronic tetanus infection of the intestinal tract as the underlying cause for symptoms of autism observed in some individuals. A significant percentage of individuals with autism have a history of extensive antibiotic use.

Oral antibiotics significantly disrupt protective intestinal microbiota, creating a favorable environment for colonization by opportunistic pathogens. Clostridium tetani is an ubiquitous anaerobic bacillus that produces a potent neurotoxin. Intestinal colonization by C. tetani, and subsequent neurotoxin release, have been demonstrated in laboratory animals which were fed vegetative cells.

The vagus nerve is capable of transporting tetanus neurotoxin (TeNT) and provides a route of ascent from the intestinal tract to the CNS. This route bypasses TeNT's normal preferential binding sites in the spinal cord, and therefore the symptoms of a typical tetanus infection are not evident. Once in the brain, TeNT disrupts the release of neurotransmitters by the proteolytic cleavage of synaptobrevin, a synaptic vesicle membrane protein. This inhibition of neurotransmitter release would explain a wide variety of behavioral deficits apparent in autism.

Lab animals injected in the brain with TeNT have exhibited many of these behaviors. Some children with autism have also shown a significant reduction in stereotyped behaviors when treated with antimicrobials effective against intestinal clostridia. When viewed as sequelae to a subacute, chronic tetanus infection, many of the puzzling abnormalities of autism have a logical basis. A review of atypical tetanus cases, and strategies to test the validity of this paper's hypothesis, are included.
PMID: 9881820 [PubMed - indexed for MEDLINE]

[Bob]

Posted by Tesla_WTC_Solution (here)

Scientific Expose

Tesla: I found an old NIH paper this morning while writing this post, hypothesizing that a sub-acute tetanus infection may account for symptoms of autism. Please read this thread and tell me what you think about the idea, and why the NIH left it as a mere hypothesis instead of proving it to be true themselves.

When the story came out a year or two ago regarding German E. Coli strains testing positive for Yersinia Pestis genes, I should have been a little more concerned about people understanding what this means. People were hospitalized, and didn't some of them die?

http://en.wikipedia.org/wiki/Transduction_(genetics)

Transduction is the process by which DNA is transferred from one bacterium to another by a virus.[1] It also refers to the process whereby foreign DNA is introduced into another cell via a viral vector. Transduction does not require physical contact between the cell donating the DNA and the cell receiving the DNA (which occurs in conjugation), and it is DNAase resistant (transformation is susceptible to DNAase). Transduction is a common tool used by molecular biologists to stably introduce a foreign gene into a host cell's genome.

I became interested in transduction (without knowing the word for it, actually) because of research done by my ex-boyfriend. He worked extensively with other scientists in a multi-national effort to develop more effective viral vectors for swapping genes in bacterial DNA.

Just before the outbreak of Black Plague-tainted E. Coli, traced to and blamed on German farms, I had emailed this man in hopes of him explaining whether or not he was aware of the possibility that his technology would enable gene swapping in the wild, in situations outside the laboratory, with potential to affect the quality of life of innocent human beings.

I never did hear back from him on whether or not his technology was capable of altering the natural flora present in the human intestines. I would imagine that my question was disturbing, if not well-timed. Within weeks of my correspondence, I heard about the outbreak of Y. Pestis-laced E. Coli in Germany.

(snipped)

Tesla - in one word - Y E S

That is the problem also with the Monsanto transduction "experiments", that the transducer doesn't always shut off, and just possibly why people appear to be having cellulose fibres showing up in the skin and calling it Morgellons.. Playing around with transduction vectors in the field in the wild is the most insane horrific program ever explored - in line with nano-particle release in the field - heck nanomachines are supposed to replace the wildness of the transduction viri..

[Flash]

Very interesting Tesla, many thanks.