Two words:
"Parasitical encumbrance"
The very definition of the witnessing of negative potential, in/by developed macro intellect in any base systems of complex dimensionally enabled quantum differential (time, 3d space, gravity, etc).
Any form of 'out of time' or FTL (anti-gravity, dimensional travel, quantum coupling, warp speeds, etc) that is extant in such an environment, will drastically decrease the ability for parasitical encumbrance to exist in said systems.
http://en.wikipedia.org/wiki/Cymothoa_exigua